SMAD3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SMAD3
Entrez Gene ID	4088
Full Name	SMAD family member 3
Synonyms	HSPC193,HsT17436,JV15-2,LDS1C,LDS3,MADH3
General protein information	Preferred Names SMAD family member 3 Names mothers against decapentaplegic homolog 3 MAD homolog 3 MAD, mothers against decapentaplegic homolog 3 SMA- and MAD-related protein 3 SMAD, mothers against DPP homolog 3 hMAD-3 hSMAD3 mad homolog JV15-2 mad protein homolog mad3 mothers against DPP homolog 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q22.33
Summary	The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009].
Disorder MIM:	603109
Disorder Html:	Loeys-Dietz syndrome 3, 613795 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005902.3	NP_005893.1	mothers against decapentaplegic homolog 3 isoform 1
NM_001145102.1	NP_001138574.1	mothers against decapentaplegic homolog 3 isoform 2
NM_001145103.1	NP_001138575.1	mothers against decapentaplegic homolog 3 isoform 3
XM_011521559.2	XP_011519861.1	mothers against decapentaplegic homolog 3 isoform X1
NM_005902.4	NP_005893.1	mothers against decapentaplegic homolog 3 isoform 1
NM_001145104.1	NP_001138576.1	mothers against decapentaplegic homolog 3 isoform 4
XM_011521559.3	XP_011519861.1	mothers against decapentaplegic homolog 3 isoform X1
XM_011521560.1	XP_011519862.1	mothers against decapentaplegic homolog 3 isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SMAD3	NP_001164300.1
Bos taurus (cattle)	SMAD3	NP_001192734.1
Mus musculus (house mouse)	Smad3	NP_058049.3
Homo sapiens (human)	SMAD3	NP_005893.1
	SMAD3	XP_001111262.1
Rattus norvegicus (Norway rat)	Smad3	NP_037227.1
Drosophila melanogaster (fruit fly)	Smox	NP_511079.1
Xenopus tropicalis (tropical clawed frog)	smad3	NP_001008436.1
Pan troglodytes (chimpanzee)	SMAD3	XP_001159972.2
Gallus gallus (chicken)	SMAD3	NP_989806.1
Danio rerio (zebrafish)	smad3b	NP_778258.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009777	XP_318870.3

Gene Ontology
Bibliography

Related articles in PubMed

Galangin enhances TGF-?1-mediated growth inhibition by suppressing phosphorylation of threonine 179 residue in Smad3 linker region.
Kwak MK, Yang KM, Park J, Lee S, Park Y, Hong E, Sun EJ, An H, Park S, Pang K, Lee J, Kang JM, Kim P, Ooshima A, Kim SJ
Biochemical and biophysical research communications494(3-4)706-713(2017 12)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Particularly, galangin effectively inhibits phosphorylation of the Thr-179 site at Smad3 linker region through suppression of CDK4 phosphorylation. Thus, galangin can be a promising candidate as a selective inhibitor to suppress phosphorylation of Smad3 linker region.
Title: Galangin enhances TGF-?1-mediated growth inhibition by suppressing phosphorylation of threonine 179 residue in Smad3 linker region.

SMAD3 transcription facttor binds RNA with large internal loops or bulges with high apparent affinity, suggesting a biological role for RNA binding by SMAD3.
Title: The SMAD3 transcription factor binds complex RNA structures with high affinity.

cPLA2alpha activates PI3K/AKT and inhibits Smad2/3 during epithelial-mesenchymal transition of hepatocellular carcinoma cells.
Title: cPLA2? activates PI3K/AKT and inhibits Smad2/3 during epithelial-mesenchymal transition of hepatocellular carcinoma cells.

c-Abl promotes TGF-beta-induced SKIP/Smad3 interaction.
Title: Enhancement of TGF-?-induced Smad3 activity by c-Abl-mediated tyrosine phosphorylation of its coactivator SKI-interacting protein (SKIP).

Therefore, our results demonstrate that autophagy counteracts the EndoMT process triggered by TGF-beta2 by decreasing the phosphorylation level of Smad3.
Title: Autophagy regulates Endothelial-Mesenchymal transition by decreasing the phosphorylation level of Smad3.

The following SMAD3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SMAD3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19966	NM_005902.4 Latest version!	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu23553	NM_001145104.1 Latest version!	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu23803	NM_001145102.1 Latest version!	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu58827	XM_011521559.3 Latest version!	Homo sapiens SMAD family member 3 (SMAD3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu23848	NM_001145103.1 Latest version!	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu58828	XM_011521560.1 Latest version!	Homo sapiens SMAD family member 3 (SMAD3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu19966	NM_005902.3	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu58827	XM_011521559.2	Homo sapiens SMAD family member 3 (SMAD3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SMAD3 ( NM_005902.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005893.1 Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19966
Clone ID Related Accession (Same CDS sequence)	NM_005902.3 , NM_005902.4
Accession Version	NM_005902.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	mothers against decapentaplegic homolog 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF058230.1, BC050743.1, U76622.1, AI991957.1, BG251847.1, BX506233.1, BQ917888.1, BM551682.1, BM722372.1, BE905995.1, AL110265.1, AF151027.1 and AA493306.1. This sequence is a reference standard in the RefSeqGene project. On or before Sep 20, 2004 this sequence version replaced NM_015400.1, NM_005902.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.67621.1, BC050743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTCCA TCCTGCCTTT CACTCCCCCG ATCGTGAAGC GCCTGCTGGG CTGGAAGAAG 
GGCGAGCAGA ACGGGCAGGA GGAGAAATGG TGCGAGAAGG CGGTCAAGAG CCTGGTCAAG 
AAACTCAAGA AGACGGGGCA GCTGGACGAG CTGGAGAAGG CCATCACCAC GCAGAACGTC 
AACACCAAGT GCATCACCAT CCCCAGGTCC CTGGATGGCC GGTTGCAGGT GTCCCATCGG 
AAGGGGCTCC CTCATGTCAT CTACTGCCGC CTGTGGCGAT GGCCAGACCT GCACAGCCAC 
CACGAGCTAC GGGCCATGGA GCTGTGTGAG TTCGCCTTCA ATATGAAGAA GGACGAGGTC 
TGCGTGAATC CCTACCACTA CCAGAGAGTA GAGACACCAG TTCTACCTCC TGTGTTGGTG 
CCACGCCACA CAGAGATCCC GGCCGAGTTC CCCCCACTGG ACGACTACAG CCATTCCATC 
CCCGAAAACA CTAACTTCCC CGCAGGCATC GAGCCCCAGA GCAATATTCC AGAGACCCCA 
CCCCCTGGCT ACCTGAGTGA AGATGGAGAA ACCAGTGACC ACCAGATGAA CCACAGCATG 
GACGCAGGTT CTCCAAACCT ATCCCCGAAT CCGATGTCCC CAGCACATAA TAACTTGGAC 
CTGCAGCCAG TTACCTACTG CGAGCCGGCC TTCTGGTGCT CCATCTCCTA CTACGAGCTG 
AACCAGCGCG TCGGGGAGAC ATTCCACGCC TCGCAGCCAT CCATGACTGT GGATGGCTTC 
ACCGACCCCT CCAATTCGGA GCGCTTCTGC CTAGGGCTGC TCTCCAATGT CAACAGGAAT 
GCAGCAGTGG AGCTGACACG GAGACACATC GGAAGAGGCG TGCGGCTCTA CTACATCGGA 
GGGGAGGTCT TCGCAGAGTG CCTCAGTGAC AGCGCTATTT TTGTCCAGTC TCCCAACTGT 
AACCAGCGCT ATGGCTGGCA CCCGGCCACC GTCTGCAAGA TCCCACCAGG ATGCAACCTG 
AAGATCTTCA ACAACCAGGA GTTCGCTGCC CTCCTGGCCC AGTCGGTCAA CCAGGGCTTT 
GAGGCTGTCT ACCAGTTGAC CCGAATGTGC ACCATCCGCA TGAGCTTCGT CAAAGGCTGG 
GGAGCGGAGT ACAGGAGACA GACTGTGACC AGTACCCCCT GCTGGATTGA GCTGCACCTG 
AATGGGCCTT TGCAGTGGCT TGACAAGGTC CTCACCCAGA TGGGCTCCCC AAGCATCCGC 
TGTTCCAGTG TGTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005893.1
CDS	299..1576
Translation	MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

Target ORF information:

RefSeq Version	NM_005902.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005902.3

ORF Insert Sequence:

ATGTCGTCCA TCCTGCCTTT CACTCCCCCG ATCGTGAAGC GCCTGCTGGG CTGGAAGAAG 
GGCGAGCAGA ACGGGCAGGA GGAGAAATGG TGCGAGAAGG CGGTCAAGAG CCTGGTCAAG 
AAACTCAAGA AGACGGGGCA GCTGGACGAG CTGGAGAAGG CCATCACCAC GCAGAACGTC 
AACACCAAGT GCATCACCAT CCCCAGGTCC CTGGATGGCC GGTTGCAGGT GTCCCATCGG 
AAGGGGCTCC CTCATGTCAT CTACTGCCGC CTGTGGCGAT GGCCAGACCT GCACAGCCAC 
CACGAGCTAC GGGCCATGGA GCTGTGTGAG TTCGCCTTCA ATATGAAGAA GGACGAGGTC 
TGCGTGAATC CCTACCACTA CCAGAGAGTA GAGACACCAG TTCTACCTCC TGTGTTGGTG 
CCACGCCACA CAGAGATCCC GGCCGAGTTC CCCCCACTGG ACGACTACAG CCATTCCATC 
CCCGAAAACA CTAACTTCCC CGCAGGCATC GAGCCCCAGA GCAATATTCC AGAGACCCCA 
CCCCCTGGCT ACCTGAGTGA AGATGGAGAA ACCAGTGACC ACCAGATGAA CCACAGCATG 
GACGCAGGTT CTCCAAACCT ATCCCCGAAT CCGATGTCCC CAGCACATAA TAACTTGGAC 
CTGCAGCCAG TTACCTACTG CGAGCCGGCC TTCTGGTGCT CCATCTCCTA CTACGAGCTG 
AACCAGCGCG TCGGGGAGAC ATTCCACGCC TCGCAGCCAT CCATGACTGT GGATGGCTTC 
ACCGACCCCT CCAATTCGGA GCGCTTCTGC CTAGGGCTGC TCTCCAATGT CAACAGGAAT 
GCAGCAGTGG AGCTGACACG GAGACACATC GGAAGAGGCG TGCGGCTCTA CTACATCGGA 
GGGGAGGTCT TCGCAGAGTG CCTCAGTGAC AGCGCTATTT TTGTCCAGTC TCCCAACTGT 
AACCAGCGCT ATGGCTGGCA CCCGGCCACC GTCTGCAAGA TCCCACCAGG ATGCAACCTG 
AAGATCTTCA ACAACCAGGA GTTCGCTGCC CTCCTGGCCC AGTCGGTCAA CCAGGGCTTT 
GAGGCTGTCT ACCAGTTGAC CCGAATGTGC ACCATCCGCA TGAGCTTCGT CAAAGGCTGG 
GGAGCGGAGT ACAGGAGACA GACTGTGACC AGTACCCCCT GCTGGATTGA GCTGCACCTG 
AATGGGCCTT TGCAGTGGCT TGACAAGGTC CTCACCCAGA TGGGCTCCCC AAGCATCCGC 
TGTTCCAGTG TGTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMAD3 ( NM_005902.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005893.1 Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19966
Clone ID Related Accession (Same CDS sequence)	NM_005902.3 , NM_005902.4
Accession Version	NM_005902.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	mothers against decapentaplegic homolog 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC087482.9 and AC012568.7. On Nov 23, 2018 this sequence version replaced NM_005902.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.67621.1, BC050743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000327367.9/ ENSP00000332973.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGTCCA TCCTGCCTTT CACTCCCCCG ATCGTGAAGC GCCTGCTGGG CTGGAAGAAG 
GGCGAGCAGA ACGGGCAGGA GGAGAAATGG TGCGAGAAGG CGGTCAAGAG CCTGGTCAAG 
AAACTCAAGA AGACGGGGCA GCTGGACGAG CTGGAGAAGG CCATCACCAC GCAGAACGTC 
AACACCAAGT GCATCACCAT CCCCAGGTCC CTGGATGGCC GGTTGCAGGT GTCCCATCGG 
AAGGGGCTCC CTCATGTCAT CTACTGCCGC CTGTGGCGAT GGCCAGACCT GCACAGCCAC 
CACGAGCTAC GGGCCATGGA GCTGTGTGAG TTCGCCTTCA ATATGAAGAA GGACGAGGTC 
TGCGTGAATC CCTACCACTA CCAGAGAGTA GAGACACCAG TTCTACCTCC TGTGTTGGTG 
CCACGCCACA CAGAGATCCC GGCCGAGTTC CCCCCACTGG ACGACTACAG CCATTCCATC 
CCCGAAAACA CTAACTTCCC CGCAGGCATC GAGCCCCAGA GCAATATTCC AGAGACCCCA 
CCCCCTGGCT ACCTGAGTGA AGATGGAGAA ACCAGTGACC ACCAGATGAA CCACAGCATG 
GACGCAGGTT CTCCAAACCT ATCCCCGAAT CCGATGTCCC CAGCACATAA TAACTTGGAC 
CTGCAGCCAG TTACCTACTG CGAGCCGGCC TTCTGGTGCT CCATCTCCTA CTACGAGCTG 
AACCAGCGCG TCGGGGAGAC ATTCCACGCC TCGCAGCCAT CCATGACTGT GGATGGCTTC 
ACCGACCCCT CCAATTCGGA GCGCTTCTGC CTAGGGCTGC TCTCCAATGT CAACAGGAAT 
GCAGCAGTGG AGCTGACACG GAGACACATC GGAAGAGGCG TGCGGCTCTA CTACATCGGA 
GGGGAGGTCT TCGCAGAGTG CCTCAGTGAC AGCGCTATTT TTGTCCAGTC TCCCAACTGT 
AACCAGCGCT ATGGCTGGCA CCCGGCCACC GTCTGCAAGA TCCCACCAGG ATGCAACCTG 
AAGATCTTCA ACAACCAGGA GTTCGCTGCC CTCCTGGCCC AGTCGGTCAA CCAGGGCTTT 
GAGGCTGTCT ACCAGTTGAC CCGAATGTGC ACCATCCGCA TGAGCTTCGT CAAAGGCTGG 
GGAGCGGAGT ACAGGAGACA GACTGTGACC AGTACCCCCT GCTGGATTGA GCTGCACCTG 
AATGGGCCTT TGCAGTGGCT TGACAAGGTC CTCACCCAGA TGGGCTCCCC AAGCATCCGC 
TGTTCCAGTG TGTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005893.1
CDS	554..1831
Translation	MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

Target ORF information:

RefSeq Version	NM_005902.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005902.4

ORF Insert Sequence:

ATGTCGTCCA TCCTGCCTTT CACTCCCCCG ATCGTGAAGC GCCTGCTGGG CTGGAAGAAG 
GGCGAGCAGA ACGGGCAGGA GGAGAAATGG TGCGAGAAGG CGGTCAAGAG CCTGGTCAAG 
AAACTCAAGA AGACGGGGCA GCTGGACGAG CTGGAGAAGG CCATCACCAC GCAGAACGTC 
AACACCAAGT GCATCACCAT CCCCAGGTCC CTGGATGGCC GGTTGCAGGT GTCCCATCGG 
AAGGGGCTCC CTCATGTCAT CTACTGCCGC CTGTGGCGAT GGCCAGACCT GCACAGCCAC 
CACGAGCTAC GGGCCATGGA GCTGTGTGAG TTCGCCTTCA ATATGAAGAA GGACGAGGTC 
TGCGTGAATC CCTACCACTA CCAGAGAGTA GAGACACCAG TTCTACCTCC TGTGTTGGTG 
CCACGCCACA CAGAGATCCC GGCCGAGTTC CCCCCACTGG ACGACTACAG CCATTCCATC 
CCCGAAAACA CTAACTTCCC CGCAGGCATC GAGCCCCAGA GCAATATTCC AGAGACCCCA 
CCCCCTGGCT ACCTGAGTGA AGATGGAGAA ACCAGTGACC ACCAGATGAA CCACAGCATG 
GACGCAGGTT CTCCAAACCT ATCCCCGAAT CCGATGTCCC CAGCACATAA TAACTTGGAC 
CTGCAGCCAG TTACCTACTG CGAGCCGGCC TTCTGGTGCT CCATCTCCTA CTACGAGCTG 
AACCAGCGCG TCGGGGAGAC ATTCCACGCC TCGCAGCCAT CCATGACTGT GGATGGCTTC 
ACCGACCCCT CCAATTCGGA GCGCTTCTGC CTAGGGCTGC TCTCCAATGT CAACAGGAAT 
GCAGCAGTGG AGCTGACACG GAGACACATC GGAAGAGGCG TGCGGCTCTA CTACATCGGA 
GGGGAGGTCT TCGCAGAGTG CCTCAGTGAC AGCGCTATTT TTGTCCAGTC TCCCAACTGT 
AACCAGCGCT ATGGCTGGCA CCCGGCCACC GTCTGCAAGA TCCCACCAGG ATGCAACCTG 
AAGATCTTCA ACAACCAGGA GTTCGCTGCC CTCCTGGCCC AGTCGGTCAA CCAGGGCTTT 
GAGGCTGTCT ACCAGTTGAC CCGAATGTGC ACCATCCGCA TGAGCTTCGT CAAAGGCTGG 
GGAGCGGAGT ACAGGAGACA GACTGTGACC AGTACCCCCT GCTGGATTGA GCTGCACCTG 
AATGGGCCTT TGCAGTGGCT TGACAAGGTC CTCACCCAGA TGGGCTCCCC AAGCATCCGC 
TGTTCCAGTG TGTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMAD3 ( NM_001145104.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138576.1 Homo sapiens SMAD family member 3 (SMAD3), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu23553
Clone ID Related Accession (Same CDS sequence)	NM_001145104.1
Accession Version	NM_001145104.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	mothers against decapentaplegic homolog 3 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA977882.1, DA755047.1 and AC012568.7. Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (4) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300614.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACCACA GCATGGACGC AGGTTCTCCA AACCTATCCC CGAATCCGAT GTCCCCAGCA 
CATAATAACT TGGACCTGCA GCCAGTTACC TACTGCGAGC CGGCCTTCTG GTGCTCCATC 
TCCTACTACG AGCTGAACCA GCGCGTCGGG GAGACATTCC ACGCCTCGCA GCCATCCATG 
ACTGTGGATG GCTTCACCGA CCCCTCCAAT TCGGAGCGCT TCTGCCTAGG GCTGCTCTCC 
AATGTCAACA GGAATGCAGC AGTGGAGCTG ACACGGAGAC ACATCGGAAG AGGCGTGCGG 
CTCTACTACA TCGGAGGGGA GGTCTTCGCA GAGTGCCTCA GTGACAGCGC TATTTTTGTC 
CAGTCTCCCA ACTGTAACCA GCGCTATGGC TGGCACCCGG CCACCGTCTG CAAGATCCCA 
CCAGGATGCA ACCTGAAGAT CTTCAACAAC CAGGAGTTCG CTGCCCTCCT GGCCCAGTCG 
GTCAACCAGG GCTTTGAGGC TGTCTACCAG TTGACCCGAA TGTGCACCAT CCGCATGAGC 
TTCGTCAAAG GCTGGGGAGC GGAGTACAGG AGACAGACTG TGACCAGTAC CCCCTGCTGG 
ATTGAGCTGC ACCTGAATGG GCCTTTGCAG TGGCTTGACA AGGTCCTCAC CCAGATGGGC 
TCCCCAAGCA TCCGCTGTTC CAGTGTGTCT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138576.1
CDS	93..785
Translation	MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

Target ORF information:

RefSeq Version	NM_001145104.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145104.1

ORF Insert Sequence:

ATGAACCACA GCATGGACGC AGGTTCTCCA AACCTATCCC CGAATCCGAT GTCCCCAGCA 
CATAATAACT TGGACCTGCA GCCAGTTACC TACTGCGAGC CGGCCTTCTG GTGCTCCATC 
TCCTACTACG AGCTGAACCA GCGCGTCGGG GAGACATTCC ACGCCTCGCA GCCATCCATG 
ACTGTGGATG GCTTCACCGA CCCCTCCAAT TCGGAGCGCT TCTGCCTAGG GCTGCTCTCC 
AATGTCAACA GGAATGCAGC AGTGGAGCTG ACACGGAGAC ACATCGGAAG AGGCGTGCGG 
CTCTACTACA TCGGAGGGGA GGTCTTCGCA GAGTGCCTCA GTGACAGCGC TATTTTTGTC 
CAGTCTCCCA ACTGTAACCA GCGCTATGGC TGGCACCCGG CCACCGTCTG CAAGATCCCA 
CCAGGATGCA ACCTGAAGAT CTTCAACAAC CAGGAGTTCG CTGCCCTCCT GGCCCAGTCG 
GTCAACCAGG GCTTTGAGGC TGTCTACCAG TTGACCCGAA TGTGCACCAT CCGCATGAGC 
TTCGTCAAAG GCTGGGGAGC GGAGTACAGG AGACAGACTG TGACCAGTAC CCCCTGCTGG 
ATTGAGCTGC ACCTGAATGG GCCTTTGCAG TGGCTTGACA AGGTCCTCAC CCAGATGGGC 
TCCCCAAGCA TCCGCTGTTC CAGTGTGTCT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMAD3 ( NM_001145102.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138574.1 Homo sapiens SMAD family member 3 (SMAD3), transcript variant 2, mRNA.

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CloneID	OHu23803
Clone ID Related Accession (Same CDS sequence)	NM_001145102.1
Accession Version	NM_001145102.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 963bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	mothers against decapentaplegic homolog 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA453132.1, AK316017.1, U76622.1 and AC012568.7. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK316017.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTGT GTGAGTTCGC CTTCAATATG AAGAAGGACG AGGTCTGCGT GAATCCCTAC 
CACTACCAGA GAGTAGAGAC ACCAGTTCTA CCTCCTGTGT TGGTGCCACG CCACACAGAG 
ATCCCGGCCG AGTTCCCCCC ACTGGACGAC TACAGCCATT CCATCCCCGA AAACACTAAC 
TTCCCCGCAG GCATCGAGCC CCAGAGCAAT ATTCCAGAGA CCCCACCCCC TGGCTACCTG 
AGTGAAGATG GAGAAACCAG TGACCACCAG ATGAACCACA GCATGGACGC AGGTTCTCCA 
AACCTATCCC CGAATCCGAT GTCCCCAGCA CATAATAACT TGGACCTGCA GCCAGTTACC 
TACTGCGAGC CGGCCTTCTG GTGCTCCATC TCCTACTACG AGCTGAACCA GCGCGTCGGG 
GAGACATTCC ACGCCTCGCA GCCATCCATG ACTGTGGATG GCTTCACCGA CCCCTCCAAT 
TCGGAGCGCT TCTGCCTAGG GCTGCTCTCC AATGTCAACA GGAATGCAGC AGTGGAGCTG 
ACACGGAGAC ACATCGGAAG AGGCGTGCGG CTCTACTACA TCGGAGGGGA GGTCTTCGCA 
GAGTGCCTCA GTGACAGCGC TATTTTTGTC CAGTCTCCCA ACTGTAACCA GCGCTATGGC 
TGGCACCCGG CCACCGTCTG CAAGATCCCA CCAGGATGCA ACCTGAAGAT CTTCAACAAC 
CAGGAGTTCG CTGCCCTCCT GGCCCAGTCG GTCAACCAGG GCTTTGAGGC TGTCTACCAG 
TTGACCCGAA TGTGCACCAT CCGCATGAGC TTCGTCAAAG GCTGGGGAGC GGAGTACAGG 
AGACAGACTG TGACCAGTAC CCCCTGCTGG ATTGAGCTGC ACCTGAATGG GCCTTTGCAG 
TGGCTTGACA AGGTCCTCAC CCAGATGGGC TCCCCAAGCA TCCGCTGTTC CAGTGTGTCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138574.1
CDS	379..1341
Translation	MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

Target ORF information:

RefSeq Version	NM_001145102.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145102.1

ORF Insert Sequence:

ATGGAGCTGT GTGAGTTCGC CTTCAATATG AAGAAGGACG AGGTCTGCGT GAATCCCTAC 
CACTACCAGA GAGTAGAGAC ACCAGTTCTA CCTCCTGTGT TGGTGCCACG CCACACAGAG 
ATCCCGGCCG AGTTCCCCCC ACTGGACGAC TACAGCCATT CCATCCCCGA AAACACTAAC 
TTCCCCGCAG GCATCGAGCC CCAGAGCAAT ATTCCAGAGA CCCCACCCCC TGGCTACCTG 
AGTGAAGATG GAGAAACCAG TGACCACCAG ATGAACCACA GCATGGACGC AGGTTCTCCA 
AACCTATCCC CGAATCCGAT GTCCCCAGCA CATAATAACT TGGACCTGCA GCCAGTTACC 
TACTGCGAGC CGGCCTTCTG GTGCTCCATC TCCTACTACG AGCTGAACCA GCGCGTCGGG 
GAGACATTCC ACGCCTCGCA GCCATCCATG ACTGTGGATG GCTTCACCGA CCCCTCCAAT 
TCGGAGCGCT TCTGCCTAGG GCTGCTCTCC AATGTCAACA GGAATGCAGC AGTGGAGCTG 
ACACGGAGAC ACATCGGAAG AGGCGTGCGG CTCTACTACA TCGGAGGGGA GGTCTTCGCA 
GAGTGCCTCA GTGACAGCGC TATTTTTGTC CAGTCTCCCA ACTGTAACCA GCGCTATGGC 
TGGCACCCGG CCACCGTCTG CAAGATCCCA CCAGGATGCA ACCTGAAGAT CTTCAACAAC 
CAGGAGTTCG CTGCCCTCCT GGCCCAGTCG GTCAACCAGG GCTTTGAGGC TGTCTACCAG 
TTGACCCGAA TGTGCACCAT CCGCATGAGC TTCGTCAAAG GCTGGGGAGC GGAGTACAGG 
AGACAGACTG TGACCAGTAC CCCCTGCTGG ATTGAGCTGC ACCTGAATGG GCCTTTGCAG 
TGGCTTGACA AGGTCCTCAC CCAGATGGGC TCCCCAAGCA TCCGCTGTTC CAGTGTGTCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMAD3 ( XM_011521559.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519861.1 Homo sapiens SMAD family member 3 (SMAD3), transcript variant X1, mRNA.

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CloneID	OHu58827
Clone ID Related Accession (Same CDS sequence)	XM_011521559.2 , XM_011521559.3
Accession Version	XM_011521559.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	mothers against decapentaplegic homolog 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011521559.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGTCCA TCCTGCCTTT CACTCCCCCG ATCGTGAAGC GCCTGCTGGG CTGGAAGAAG 
GGCGAGCAGA ACGGGCAGGA GGAGAAATGG TGCGAGAAGG CGGTCAAGAG CCTGGTCAAG 
AAACTCAAGA AGACGGGGCA GCTGGACGAG CTGGAGAAGG CCATCACCAC GCAGAACGTC 
AACACCAAGT GCATCACCAT CCCCAGGTCC CTGGATGGCC GGTTGCAGGT GTCCCATCGG 
AAGGGGCTCC CTCATGTCAT CTACTGCCGC CTGTGGCGAT GGCCAGACCT GCACAGCCAC 
CACGAGCTAC GGGCCATGGA GCTGTGTGAG TTCGCCTTCA ATATGAAGAA GGACGAGGTC 
TGCGTGAATC CCTACCACTA CCAGAGAGTA GAGACACCAG AGACCCCACC CCCTGGCTAC 
CTGAGTGAAG ATGGAGAAAC CAGTGACCAC CAGATGAACC ACAGCATGGA CGCAGGTTCT 
CCAAACCTAT CCCCGAATCC GATGTCCCCA GCACATAATA ACTTGGACCT GCAGCCAGTT 
ACCTACTGCG AGCCGGCCTT CTGGTGCTCC ATCTCCTACT ACGAGCTGAA CCAGCGCGTC 
GGGGAGACAT TCCACGCCTC GCAGCCATCC ATGACTGTGG ATGGCTTCAC CGACCCCTCC 
AATTCGGAGC GCTTCTGCCT AGGGCTGCTC TCCAATGTCA ACAGGAATGC AGCAGTGGAG 
CTGACACGGA GACACATCGG AAGAGGCGTG CGGCTCTACT ACATCGGAGG GGAGGTCTTC 
GCAGAGTGCC TCAGTGACAG CGCTATTTTT GTCCAGTCTC CCAACTGTAA CCAGCGCTAT 
GGCTGGCACC CGGCCACCGT CTGCAAGATC CCACCAGGAT GCAACCTGAA GATCTTCAAC 
AACCAGGAGT TCGCTGCCCT CCTGGCCCAG TCGGTCAACC AGGGCTTTGA GGCTGTCTAC 
CAGTTGACCC GAATGTGCAC CATCCGCATG AGCTTCGTCA AAGGCTGGGG AGCGGAGTAC 
AGGAGACAGA CTGTGACCAG TACCCCCTGC TGGATTGAGC TGCACCTGAA TGGGCCTTTG 
CAGTGGCTTG ACAAGGTCCT CACCCAGATG GGCTCCCCAA GCATCCGCTG TTCCAGTGTG 
TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519861.1
CDS	458..1603
Translation	MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

Target ORF information:

RefSeq Version	XM_011521559.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SMAD family member 3 (SMAD3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521559.2

ORF Insert Sequence:

ATGTCGTCCA TCCTGCCTTT CACTCCCCCG ATCGTGAAGC GCCTGCTGGG CTGGAAGAAG 
GGCGAGCAGA ACGGGCAGGA GGAGAAATGG TGCGAGAAGG CGGTCAAGAG CCTGGTCAAG 
AAACTCAAGA AGACGGGGCA GCTGGACGAG CTGGAGAAGG CCATCACCAC GCAGAACGTC 
AACACCAAGT GCATCACCAT CCCCAGGTCC CTGGATGGCC GGTTGCAGGT GTCCCATCGG 
AAGGGGCTCC CTCATGTCAT CTACTGCCGC CTGTGGCGAT GGCCAGACCT GCACAGCCAC 
CACGAGCTAC GGGCCATGGA GCTGTGTGAG TTCGCCTTCA ATATGAAGAA GGACGAGGTC 
TGCGTGAATC CCTACCACTA CCAGAGAGTA GAGACACCAG AGACCCCACC CCCTGGCTAC 
CTGAGTGAAG ATGGAGAAAC CAGTGACCAC CAGATGAACC ACAGCATGGA CGCAGGTTCT 
CCAAACCTAT CCCCGAATCC GATGTCCCCA GCACATAATA ACTTGGACCT GCAGCCAGTT 
ACCTACTGCG AGCCGGCCTT CTGGTGCTCC ATCTCCTACT ACGAGCTGAA CCAGCGCGTC 
GGGGAGACAT TCCACGCCTC GCAGCCATCC ATGACTGTGG ATGGCTTCAC CGACCCCTCC 
AATTCGGAGC GCTTCTGCCT AGGGCTGCTC TCCAATGTCA ACAGGAATGC AGCAGTGGAG 
CTGACACGGA GACACATCGG AAGAGGCGTG CGGCTCTACT ACATCGGAGG GGAGGTCTTC 
GCAGAGTGCC TCAGTGACAG CGCTATTTTT GTCCAGTCTC CCAACTGTAA CCAGCGCTAT 
GGCTGGCACC CGGCCACCGT CTGCAAGATC CCACCAGGAT GCAACCTGAA GATCTTCAAC 
AACCAGGAGT TCGCTGCCCT CCTGGCCCAG TCGGTCAACC AGGGCTTTGA GGCTGTCTAC 
CAGTTGACCC GAATGTGCAC CATCCGCATG AGCTTCGTCA AAGGCTGGGG AGCGGAGTAC 
AGGAGACAGA CTGTGACCAG TACCCCCTGC TGGATTGAGC TGCACCTGAA TGGGCCTTTG 
CAGTGGCTTG ACAAGGTCCT CACCCAGATG GGCTCCCCAA GCATCCGCTG TTCCAGTGTG 
TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMAD3 ( XM_011521559.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519861.1 Homo sapiens SMAD family member 3 (SMAD3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58827
Clone ID Related Accession (Same CDS sequence)	XM_011521559.2 , XM_011521559.3
Accession Version	XM_011521559.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mothers against decapentaplegic homolog 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011521559.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGTCCA TCCTGCCTTT CACTCCCCCG ATCGTGAAGC GCCTGCTGGG CTGGAAGAAG 
GGCGAGCAGA ACGGGCAGGA GGAGAAATGG TGCGAGAAGG CGGTCAAGAG CCTGGTCAAG 
AAACTCAAGA AGACGGGGCA GCTGGACGAG CTGGAGAAGG CCATCACCAC GCAGAACGTC 
AACACCAAGT GCATCACCAT CCCCAGGTCC CTGGATGGCC GGTTGCAGGT GTCCCATCGG 
AAGGGGCTCC CTCATGTCAT CTACTGCCGC CTGTGGCGAT GGCCAGACCT GCACAGCCAC 
CACGAGCTAC GGGCCATGGA GCTGTGTGAG TTCGCCTTCA ATATGAAGAA GGACGAGGTC 
TGCGTGAATC CCTACCACTA CCAGAGAGTA GAGACACCAG AGACCCCACC CCCTGGCTAC 
CTGAGTGAAG ATGGAGAAAC CAGTGACCAC CAGATGAACC ACAGCATGGA CGCAGGTTCT 
CCAAACCTAT CCCCGAATCC GATGTCCCCA GCACATAATA ACTTGGACCT GCAGCCAGTT 
ACCTACTGCG AGCCGGCCTT CTGGTGCTCC ATCTCCTACT ACGAGCTGAA CCAGCGCGTC 
GGGGAGACAT TCCACGCCTC GCAGCCATCC ATGACTGTGG ATGGCTTCAC CGACCCCTCC 
AATTCGGAGC GCTTCTGCCT AGGGCTGCTC TCCAATGTCA ACAGGAATGC AGCAGTGGAG 
CTGACACGGA GACACATCGG AAGAGGCGTG CGGCTCTACT ACATCGGAGG GGAGGTCTTC 
GCAGAGTGCC TCAGTGACAG CGCTATTTTT GTCCAGTCTC CCAACTGTAA CCAGCGCTAT 
GGCTGGCACC CGGCCACCGT CTGCAAGATC CCACCAGGAT GCAACCTGAA GATCTTCAAC 
AACCAGGAGT TCGCTGCCCT CCTGGCCCAG TCGGTCAACC AGGGCTTTGA GGCTGTCTAC 
CAGTTGACCC GAATGTGCAC CATCCGCATG AGCTTCGTCA AAGGCTGGGG AGCGGAGTAC 
AGGAGACAGA CTGTGACCAG TACCCCCTGC TGGATTGAGC TGCACCTGAA TGGGCCTTTG 
CAGTGGCTTG ACAAGGTCCT CACCCAGATG GGCTCCCCAA GCATCCGCTG TTCCAGTGTG 
TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519861.1
CDS	43..1188
Translation	MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

Target ORF information:

RefSeq Version	XM_011521559.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SMAD family member 3 (SMAD3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521559.3

ORF Insert Sequence:

ATGTCGTCCA TCCTGCCTTT CACTCCCCCG ATCGTGAAGC GCCTGCTGGG CTGGAAGAAG 
GGCGAGCAGA ACGGGCAGGA GGAGAAATGG TGCGAGAAGG CGGTCAAGAG CCTGGTCAAG 
AAACTCAAGA AGACGGGGCA GCTGGACGAG CTGGAGAAGG CCATCACCAC GCAGAACGTC 
AACACCAAGT GCATCACCAT CCCCAGGTCC CTGGATGGCC GGTTGCAGGT GTCCCATCGG 
AAGGGGCTCC CTCATGTCAT CTACTGCCGC CTGTGGCGAT GGCCAGACCT GCACAGCCAC 
CACGAGCTAC GGGCCATGGA GCTGTGTGAG TTCGCCTTCA ATATGAAGAA GGACGAGGTC 
TGCGTGAATC CCTACCACTA CCAGAGAGTA GAGACACCAG AGACCCCACC CCCTGGCTAC 
CTGAGTGAAG ATGGAGAAAC CAGTGACCAC CAGATGAACC ACAGCATGGA CGCAGGTTCT 
CCAAACCTAT CCCCGAATCC GATGTCCCCA GCACATAATA ACTTGGACCT GCAGCCAGTT 
ACCTACTGCG AGCCGGCCTT CTGGTGCTCC ATCTCCTACT ACGAGCTGAA CCAGCGCGTC 
GGGGAGACAT TCCACGCCTC GCAGCCATCC ATGACTGTGG ATGGCTTCAC CGACCCCTCC 
AATTCGGAGC GCTTCTGCCT AGGGCTGCTC TCCAATGTCA ACAGGAATGC AGCAGTGGAG 
CTGACACGGA GACACATCGG AAGAGGCGTG CGGCTCTACT ACATCGGAGG GGAGGTCTTC 
GCAGAGTGCC TCAGTGACAG CGCTATTTTT GTCCAGTCTC CCAACTGTAA CCAGCGCTAT 
GGCTGGCACC CGGCCACCGT CTGCAAGATC CCACCAGGAT GCAACCTGAA GATCTTCAAC 
AACCAGGAGT TCGCTGCCCT CCTGGCCCAG TCGGTCAACC AGGGCTTTGA GGCTGTCTAC 
CAGTTGACCC GAATGTGCAC CATCCGCATG AGCTTCGTCA AAGGCTGGGG AGCGGAGTAC 
AGGAGACAGA CTGTGACCAG TACCCCCTGC TGGATTGAGC TGCACCTGAA TGGGCCTTTG 
CAGTGGCTTG ACAAGGTCCT CACCCAGATG GGCTCCCCAA GCATCCGCTG TTCCAGTGTG 
TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMAD3 ( NM_001145103.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138575.1 Homo sapiens SMAD family member 3 (SMAD3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu23848
Clone ID Related Accession (Same CDS sequence)	NM_001145103.1
Accession Version	NM_001145103.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	mothers against decapentaplegic homolog 3 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298139.1, U76622.1 and AC012568.7. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298139.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTTGCC TGCACCCTAG GCAAACGTGG AAAGGCGCAG CTCTGGTACA CCGGAAAGCA 
TGGTGGATGG GGAGGTCCCT GGATGGCCGG TTGCAGGTGT CCCATCGGAA GGGGCTCCCT 
CATGTCATCT ACTGCCGCCT GTGGCGATGG CCAGACCTGC ACAGCCACCA CGAGCTACGG 
GCCATGGAGC TGTGTGAGTT CGCCTTCAAT ATGAAGAAGG ACGAGGTCTG CGTGAATCCC 
TACCACTACC AGAGAGTAGA GACACCAGTT CTACCTCCTG TGTTGGTGCC ACGCCACACA 
GAGATCCCGG CCGAGTTCCC CCCACTGGAC GACTACAGCC ATTCCATCCC CGAAAACACT 
AACTTCCCCG CAGGCATCGA GCCCCAGAGC AATATTCCAG AGACCCCACC CCCTGGCTAC 
CTGAGTGAAG ATGGAGAAAC CAGTGACCAC CAGATGAACC ACAGCATGGA CGCAGGTTCT 
CCAAACCTAT CCCCGAATCC GATGTCCCCA GCACATAATA ACTTGGACCT GCAGCCAGTT 
ACCTACTGCG AGCCGGCCTT CTGGTGCTCC ATCTCCTACT ACGAGCTGAA CCAGCGCGTC 
GGGGAGACAT TCCACGCCTC GCAGCCATCC ATGACTGTGG ATGGCTTCAC CGACCCCTCC 
AATTCGGAGC GCTTCTGCCT AGGGCTGCTC TCCAATGTCA ACAGGAATGC AGCAGTGGAG 
CTGACACGGA GACACATCGG AAGAGGCGTG CGGCTCTACT ACATCGGAGG GGAGGTCTTC 
GCAGAGTGCC TCAGTGACAG CGCTATTTTT GTCCAGTCTC CCAACTGTAA CCAGCGCTAT 
GGCTGGCACC CGGCCACCGT CTGCAAGATC CCACCAGGAT GCAACCTGAA GATCTTCAAC 
AACCAGGAGT TCGCTGCCCT CCTGGCCCAG TCGGTCAACC AGGGCTTTGA GGCTGTCTAC 
CAGTTGACCC GAATGTGCAC CATCCGCATG AGCTTCGTCA AAGGCTGGGG AGCGGAGTAC 
AGGAGACAGA CTGTGACCAG TACCCCCTGC TGGATTGAGC TGCACCTGAA TGGGCCTTTG 
CAGTGGCTTG ACAAGGTCCT CACCCAGATG GGCTCCCCAA GCATCCGCTG TTCCAGTGTG 
TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138575.1
CDS	7..1152
Translation	MSCLHPRQTWKGAALVHRKAWWMGRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

Target ORF information:

RefSeq Version	NM_001145103.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SMAD family member 3 (SMAD3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145103.1

ORF Insert Sequence:

ATGTCTTGCC TGCACCCTAG GCAAACGTGG AAAGGCGCAG CTCTGGTACA CCGGAAAGCA 
TGGTGGATGG GGAGGTCCCT GGATGGCCGG TTGCAGGTGT CCCATCGGAA GGGGCTCCCT 
CATGTCATCT ACTGCCGCCT GTGGCGATGG CCAGACCTGC ACAGCCACCA CGAGCTACGG 
GCCATGGAGC TGTGTGAGTT CGCCTTCAAT ATGAAGAAGG ACGAGGTCTG CGTGAATCCC 
TACCACTACC AGAGAGTAGA GACACCAGTT CTACCTCCTG TGTTGGTGCC ACGCCACACA 
GAGATCCCGG CCGAGTTCCC CCCACTGGAC GACTACAGCC ATTCCATCCC CGAAAACACT 
AACTTCCCCG CAGGCATCGA GCCCCAGAGC AATATTCCAG AGACCCCACC CCCTGGCTAC 
CTGAGTGAAG ATGGAGAAAC CAGTGACCAC CAGATGAACC ACAGCATGGA CGCAGGTTCT 
CCAAACCTAT CCCCGAATCC GATGTCCCCA GCACATAATA ACTTGGACCT GCAGCCAGTT 
ACCTACTGCG AGCCGGCCTT CTGGTGCTCC ATCTCCTACT ACGAGCTGAA CCAGCGCGTC 
GGGGAGACAT TCCACGCCTC GCAGCCATCC ATGACTGTGG ATGGCTTCAC CGACCCCTCC 
AATTCGGAGC GCTTCTGCCT AGGGCTGCTC TCCAATGTCA ACAGGAATGC AGCAGTGGAG 
CTGACACGGA GACACATCGG AAGAGGCGTG CGGCTCTACT ACATCGGAGG GGAGGTCTTC 
GCAGAGTGCC TCAGTGACAG CGCTATTTTT GTCCAGTCTC CCAACTGTAA CCAGCGCTAT 
GGCTGGCACC CGGCCACCGT CTGCAAGATC CCACCAGGAT GCAACCTGAA GATCTTCAAC 
AACCAGGAGT TCGCTGCCCT CCTGGCCCAG TCGGTCAACC AGGGCTTTGA GGCTGTCTAC 
CAGTTGACCC GAATGTGCAC CATCCGCATG AGCTTCGTCA AAGGCTGGGG AGCGGAGTAC 
AGGAGACAGA CTGTGACCAG TACCCCCTGC TGGATTGAGC TGCACCTGAA TGGGCCTTTG 
CAGTGGCTTG ACAAGGTCCT CACCCAGATG GGCTCCCCAA GCATCCGCTG TTCCAGTGTG 
TCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMAD3 ( XM_011521560.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519862.1 Homo sapiens SMAD family member 3 (SMAD3), transcript variant X2, mRNA.

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CloneID	OHu58828
Clone ID Related Accession (Same CDS sequence)	XM_011521560.1
Accession Version	XM_011521560.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mothers against decapentaplegic homolog 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGACTT TTGCCCCAAA CTGTGGACAG AGCGTATGTC CTGAGCGAGG ATCAACTCTG 
TCCCTGGATG GCCGGTTGCA GGTGTCCCAT CGGAAGGGGC TCCCTCATGT CATCTACTGC 
CGCCTGTGGC GATGGCCAGA CCTGCACAGC CACCACGAGC TACGGGCCAT GGAGCTGTGT 
GAGTTCGCCT TCAATATGAA GAAGGACGAG GTCTGCGTGA ATCCCTACCA CTACCAGAGA 
GTAGAGACAC CAGTTCTACC TCCTGTGTTG GTGCCACGCC ACACAGAGAT CCCGGCCGAG 
TTCCCCCCAC TGGACGACTA CAGCCATTCC ATCCCCGAAA ACACTAACTT CCCCGCAGGC 
ATCGAGCCCC AGAGCAATAT TCCAGAGACC CCACCCCCTG GCTACCTGAG TGAAGATGGA 
GAAACCAGTG ACCACCAGAT GAACCACAGC ATGGACGCAG GTTCTCCAAA CCTATCCCCG 
AATCCGATGT CCCCAGCACA TAATAACTTG GACCTGCAGC CAGTTACCTA CTGCGAGCCG 
GCCTTCTGGT GCTCCATCTC CTACTACGAG CTGAACCAGC GCGTCGGGGA GACATTCCAC 
GCCTCGCAGC CATCCATGAC TGTGGATGGC TTCACCGACC CCTCCAATTC GGAGCGCTTC 
TGCCTAGGGC TGCTCTCCAA TGTCAACAGG AATGCAGCAG TGGAGCTGAC ACGGAGACAC 
ATCGGAAGAG GCGTGCGGCT CTACTACATC GGAGGGGAGG TCTTCGCAGA GTGCCTCAGT 
GACAGCGCTA TTTTTGTCCA GTCTCCCAAC TGTAACCAGC GCTATGGCTG GCACCCGGCC 
ACCGTCTGCA AGATCCCACC AGGATGCAAC CTGAAGATCT TCAACAACCA GGAGTTCGCT 
GCCCTCCTGG CCCAGTCGGT CAACCAGGGC TTTGAGGCTG TCTACCAGTT GACCCGAATG 
TGCACCATCC GCATGAGCTT CGTCAAAGGC TGGGGAGCGG AGTACAGGAG ACAGACTGTG 
ACCAGTACCC CCTGCTGGAT TGAGCTGCAC CTGAATGGGC CTTTGCAGTG GCTTGACAAG 
GTCCTCACCC AGATGGGCTC CCCAAGCATC CGCTGTTCCA GTGTGTCTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519862.1
CDS	385..1515
Translation	MWTFAPNCGQSVCPERGSTLSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

Target ORF information:

RefSeq Version	XM_011521560.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SMAD family member 3 (SMAD3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521560.1

ORF Insert Sequence:

ATGTGGACTT TTGCCCCAAA CTGTGGACAG AGCGTATGTC CTGAGCGAGG ATCAACTCTG 
TCCCTGGATG GCCGGTTGCA GGTGTCCCAT CGGAAGGGGC TCCCTCATGT CATCTACTGC 
CGCCTGTGGC GATGGCCAGA CCTGCACAGC CACCACGAGC TACGGGCCAT GGAGCTGTGT 
GAGTTCGCCT TCAATATGAA GAAGGACGAG GTCTGCGTGA ATCCCTACCA CTACCAGAGA 
GTAGAGACAC CAGTTCTACC TCCTGTGTTG GTGCCACGCC ACACAGAGAT CCCGGCCGAG 
TTCCCCCCAC TGGACGACTA CAGCCATTCC ATCCCCGAAA ACACTAACTT CCCCGCAGGC 
ATCGAGCCCC AGAGCAATAT TCCAGAGACC CCACCCCCTG GCTACCTGAG TGAAGATGGA 
GAAACCAGTG ACCACCAGAT GAACCACAGC ATGGACGCAG GTTCTCCAAA CCTATCCCCG 
AATCCGATGT CCCCAGCACA TAATAACTTG GACCTGCAGC CAGTTACCTA CTGCGAGCCG 
GCCTTCTGGT GCTCCATCTC CTACTACGAG CTGAACCAGC GCGTCGGGGA GACATTCCAC 
GCCTCGCAGC CATCCATGAC TGTGGATGGC TTCACCGACC CCTCCAATTC GGAGCGCTTC 
TGCCTAGGGC TGCTCTCCAA TGTCAACAGG AATGCAGCAG TGGAGCTGAC ACGGAGACAC 
ATCGGAAGAG GCGTGCGGCT CTACTACATC GGAGGGGAGG TCTTCGCAGA GTGCCTCAGT 
GACAGCGCTA TTTTTGTCCA GTCTCCCAAC TGTAACCAGC GCTATGGCTG GCACCCGGCC 
ACCGTCTGCA AGATCCCACC AGGATGCAAC CTGAAGATCT TCAACAACCA GGAGTTCGCT 
GCCCTCCTGG CCCAGTCGGT CAACCAGGGC TTTGAGGCTG TCTACCAGTT GACCCGAATG 
TGCACCATCC GCATGAGCTT CGTCAAAGGC TGGGGAGCGG AGTACAGGAG ACAGACTGTG 
ACCAGTACCC CCTGCTGGAT TGAGCTGCAC CTGAATGGGC CTTTGCAGTG GCTTGACAAG 
GTCCTCACCC AGATGGGCTC CCCAAGCATC CGCTGTTCCA GTGTGTCTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Galangin enhances TGF-?1-mediated growth inhibition by suppressing phosphorylation of threonine 179 residue in Smad3 linker region.
Biochemical and biophysical research communications494(3-4)706-713(2017 12)
Kwak MK,Yang KM,Park J,Lee S,Park Y,Hong E,Sun EJ,An H,Park S,Pang K,Lee J,Kang JM,Kim P,Ooshima A,Kim SJ

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SMAD3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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