Gene Symbol | M6PR |
Entrez Gene ID | 4074 |
Full Name | mannose-6-phosphate receptor, cation dependent |
Synonyms | CD-M6PR,CD-MPR,MPR 46,MPR-46,MPR46,SMPR |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]. |
Disorder MIM: |