TACSTD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TACSTD2
Entrez Gene ID	4070
Full Name	tumor associated calcium signal transducer 2
Synonyms	EGP-1,EGP1,GA733-1,GA7331,GP50,M1S1,TROP2
General protein information	Preferred Names tumor associated calcium signal transducer 2 Names tumor-associated calcium signal transducer 2 40kD glycoprotein, identified by monoclonal antibody GA733 cell surface glycoprotein TROP2 cell surface glycoprotein Trop-2 epithelial glycoprotein-1 gastrointestinal tumor-associated antigen GA7331 membrane component, chromosome 1, surface marker 1 pancreatic carcinoma marker protein GA733-1 pancreatic carcinoma marker protein GA7331 truncated TACSTD2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p32.1
Summary	This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009].
Disorder MIM:	137290
Disorder Html:	Corneal dystrophy, gelatinous drop-like, 204870 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002353.3	NP_002344.2	tumor-associated calcium signal transducer 2 precursor
NM_002353.2	NP_002344.2	tumor-associated calcium signal transducer 2 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tacstd2	NP_064431.2
	LOC716334	XP_001114599.1
Canis lupus familiaris (dog)	TACSTD2	XP_852842.3
Homo sapiens (human)	TACSTD2	NP_002344.2
Pan troglodytes (chimpanzee)	TACSTD2	XP_513439.2
Bos taurus (cattle)	TACSTD2	XP_002686409.1
Rattus norvegicus (Norway rat)	Tacstd2	NP_001009540.2
Gallus gallus (chicken)	TACSTD2	NP_001264605.1

Gene Ontology
Bibliography

Related articles in PubMed

Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization.
Calabrese G, Crescenzi C, Morizio E, Palka G, Guerra E, Alberti S
Cytogenetics and cell genetics92(1-2)164-5(2001)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results suggested that trop2 facilitated neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway.
Title: Tumor-associated calcium signal transducer 2 regulates neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway.

we compared the diagnostic value of TROP-2 expression in distinguishing between benign and malignant thyroid lesions to those of HBME-1, CK19 and galectin-3
Title: Diagnostic value of TROP-2 expression in papillary thyroid carcinoma and comparison with HBME-1, galectin-3 and cytokeratin 19.

TROP2 may play a crucial role in COPD by affecting basal cells function and thus airway remodeling through increased basal cells hyperplasia
Title: Increased expression of TROP2 in airway basal cells potentially contributes to airway remodeling in chronic obstructive pulmonary disease.

TROP-2 membranous staining is a very sensitive and specific marker for the classic and tall cell variants of papillary thyroid carcinoma, and for papillary microcarcinomas , with high overall specificity for papillary thyroid carcinoma
Title: TROP-2 immunohistochemistry: a highly accurate method in the differential diagnosis of papillary thyroid carcinoma.

Findings suggest that high TROP2 expression identifies distinct cell sub-populations in androgen-sensitive and androgen-independent prostate tumors and that it may be a predictive biomarker for prostate cancer treatment response in androgen-sensitive tumors.
Title: High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells.

The following TACSTD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TACSTD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18030	NM_002353.3 Latest version!	Homo sapiens tumor associated calcium signal transducer 2 (TACSTD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
View Old Accession Versions >>
OHu18030	NM_002353.2	Homo sapiens tumor associated calcium signal transducer 2 (TACSTD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TACSTD2 ( NM_002353.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002344.2 Homo sapiens tumor associated calcium signal transducer 2 (TACSTD2), mRNA.

Price & Availability↑

CloneID	OHu18030
Clone ID Related Accession (Same CDS sequence)	NM_002353.3 , NM_002353.2
Accession Version	NM_002353.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	tumor-associated calcium signal transducer 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AW052118.1, CV027795.1, BM765888.1, CD722224.1 and AI201870.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_002353.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: SRR7346977.534454.1, SRR7346977.611447.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371225.4/ ENSP00000360269.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTCGGG GCCCCGGCCT CGCGCCGCCA CCGCTGCGGC TGCCGCTGCT GCTGCTGGTG 
CTGGCGGCGG TGACCGGCCA CACGGCCGCG CAGGACAACT GCACGTGTCC CACCAACAAG 
ATGACCGTGT GCAGCCCCGA CGGCCCCGGC GGCCGCTGCC AGTGCCGCGC GCTGGGCTCG 
GGCATGGCGG TCGACTGCTC CACGCTGACC TCCAAGTGTC TGCTGCTCAA GGCGCGCATG 
AGCGCCCCCA AGAACGCCCG CACGCTGGTG CGGCCGAGTG AGCACGCGCT CGTGGACAAC 
GATGGCCTCT ACGACCCCGA CTGCGACCCC GAGGGCCGCT TCAAGGCGCG CCAGTGCAAC 
CAGACGTCGG TGTGCTGGTG CGTGAACTCG GTGGGCGTGC GCCGCACGGA CAAGGGCGAC 
CTGAGCCTAC GCTGCGATGA GCTGGTGCGC ACCCACCACA TCCTCATTGA CCTGCGCCAC 
CGCCCCACCG CCGGCGCCTT CAACCACTCA GACCTGGACG CCGAGCTGAG GCGGCTCTTC 
CGCGAGCGCT ATCGGCTGCA CCCCAAGTTC GTGGCGGCCG TGCACTACGA GCAGCCCACC 
ATCCAGATCG AGCTGCGGCA GAACACGTCT CAGAAGGCCG CCGGTGACGT GGATATCGGC 
GATGCCGCCT ACTACTTCGA GAGGGACATC AAGGGCGAGT CTCTATTCCA GGGCCGCGGC 
GGCCTGGACT TGCGCGTGCG CGGAGAACCC CTGCAGGTGG AGCGCACGCT CATCTATTAC 
CTGGACGAGA TTCCCCCGAA GTTCTCCATG AAGCGCCTCA CCGCCGGCCT CATCGCCGTC 
ATCGTGGTGG TCGTGGTGGC CCTCGTCGCC GGCATGGCCG TCCTGGTGAT CACCAACCGG 
AGAAAGTCGG GGAAGTACAA GAAGGTGGAG ATCAAGGAAC TGGGGGAGTT GAGAAAGGAA 
CCGAGCTTGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002344.2
CDS	97..1068
Translation	MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDGPGGRCQCRALGSGMAVDCSTLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCDPEGRFKARQCNQTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAELRRLFRERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDIKGESLFQGRGGLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLTAGLIAVIVVVVVALVAGMAVLVITNRRKSGKYKKVEIKELGELRKEPSL

Target ORF information:

RefSeq Version	NM_002353.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tumor associated calcium signal transducer 2 (TACSTD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002353.3

ORF Insert Sequence:

ATGGCTCGGG GCCCCGGCCT CGCGCCGCCA CCGCTGCGGC TGCCGCTGCT GCTGCTGGTG 
CTGGCGGCGG TGACCGGCCA CACGGCCGCG CAGGACAACT GCACGTGTCC CACCAACAAG 
ATGACCGTGT GCAGCCCCGA CGGCCCCGGC GGCCGCTGCC AGTGCCGCGC GCTGGGCTCG 
GGCATGGCGG TCGACTGCTC CACGCTGACC TCCAAGTGTC TGCTGCTCAA GGCGCGCATG 
AGCGCCCCCA AGAACGCCCG CACGCTGGTG CGGCCGAGTG AGCACGCGCT CGTGGACAAC 
GATGGCCTCT ACGACCCCGA CTGCGACCCC GAGGGCCGCT TCAAGGCGCG CCAGTGCAAC 
CAGACGTCGG TGTGCTGGTG CGTGAACTCG GTGGGCGTGC GCCGCACGGA CAAGGGCGAC 
CTGAGCCTAC GCTGCGATGA GCTGGTGCGC ACCCACCACA TCCTCATTGA CCTGCGCCAC 
CGCCCCACCG CCGGCGCCTT CAACCACTCA GACCTGGACG CCGAGCTGAG GCGGCTCTTC 
CGCGAGCGCT ATCGGCTGCA CCCCAAGTTC GTGGCGGCCG TGCACTACGA GCAGCCCACC 
ATCCAGATCG AGCTGCGGCA GAACACGTCT CAGAAGGCCG CCGGTGACGT GGATATCGGC 
GATGCCGCCT ACTACTTCGA GAGGGACATC AAGGGCGAGT CTCTATTCCA GGGCCGCGGC 
GGCCTGGACT TGCGCGTGCG CGGAGAACCC CTGCAGGTGG AGCGCACGCT CATCTATTAC 
CTGGACGAGA TTCCCCCGAA GTTCTCCATG AAGCGCCTCA CCGCCGGCCT CATCGCCGTC 
ATCGTGGTGG TCGTGGTGGC CCTCGTCGCC GGCATGGCCG TCCTGGTGAT CACCAACCGG 
AGAAAGTCGG GGAAGTACAA GAAGGTGGAG ATCAAGGAAC TGGGGGAGTT GAGAAAGGAA 
CCGAGCTTGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TACSTD2 ( NM_002353.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002344.2 Homo sapiens tumor associated calcium signal transducer 2 (TACSTD2), mRNA.

Price & Availability↑

CloneID	OHu18030
Clone ID Related Accession (Same CDS sequence)	NM_002353.3 , NM_002353.2
Accession Version	NM_002353.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	tumor-associated calcium signal transducer 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AW052118.1, CV027795.1, BM765888.1, CD722224.1 and AI201870.1. This sequence is a reference standard in the RefSeqGene project. On Feb 2, 2008 this sequence version replaced NM_002353.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGGCTCGGG GCCCCGGCCT CGCGCCGCCA CCGCTGCGGC TGCCGCTGCT GCTGCTGGTG 
CTGGCGGCGG TGACCGGCCA CACGGCCGCG CAGGACAACT GCACGTGTCC CACCAACAAG 
ATGACCGTGT GCAGCCCCGA CGGCCCCGGC GGCCGCTGCC AGTGCCGCGC GCTGGGCTCG 
GGCATGGCGG TCGACTGCTC CACGCTGACC TCCAAGTGTC TGCTGCTCAA GGCGCGCATG 
AGCGCCCCCA AGAACGCCCG CACGCTGGTG CGGCCGAGTG AGCACGCGCT CGTGGACAAC 
GATGGCCTCT ACGACCCCGA CTGCGACCCC GAGGGCCGCT TCAAGGCGCG CCAGTGCAAC 
CAGACGTCGG TGTGCTGGTG CGTGAACTCG GTGGGCGTGC GCCGCACGGA CAAGGGCGAC 
CTGAGCCTAC GCTGCGATGA GCTGGTGCGC ACCCACCACA TCCTCATTGA CCTGCGCCAC 
CGCCCCACCG CCGGCGCCTT CAACCACTCA GACCTGGACG CCGAGCTGAG GCGGCTCTTC 
CGCGAGCGCT ATCGGCTGCA CCCCAAGTTC GTGGCGGCCG TGCACTACGA GCAGCCCACC 
ATCCAGATCG AGCTGCGGCA GAACACGTCT CAGAAGGCCG CCGGTGACGT GGATATCGGC 
GATGCCGCCT ACTACTTCGA GAGGGACATC AAGGGCGAGT CTCTATTCCA GGGCCGCGGC 
GGCCTGGACT TGCGCGTGCG CGGAGAACCC CTGCAGGTGG AGCGCACGCT CATCTATTAC 
CTGGACGAGA TTCCCCCGAA GTTCTCCATG AAGCGCCTCA CCGCCGGCCT CATCGCCGTC 
ATCGTGGTGG TCGTGGTGGC CCTCGTCGCC GGCATGGCCG TCCTGGTGAT CACCAACCGG 
AGAAAGTCGG GGAAGTACAA GAAGGTGGAG ATCAAGGAAC TGGGGGAGTT GAGAAAGGAA 
CCGAGCTTGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002344.2
CDS	339..1310
Translation	MARGPGLAPPPLRLPLLLLVLAAVTGHTAAQDNCTCPTNKMTVCSPDGPGGRCQCRALGSGMAVDCSTLTSKCLLLKARMSAPKNARTLVRPSEHALVDNDGLYDPDCDPEGRFKARQCNQTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAELRRLFRERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDIKGESLFQGRGGLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLTAGLIAVIVVVVVALVAGMAVLVITNRRKSGKYKKVEIKELGELRKEPSL

Target ORF information:

RefSeq Version	NM_002353.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tumor associated calcium signal transducer 2 (TACSTD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002353.2

ORF Insert Sequence:

ATGGCTCGGG GCCCCGGCCT CGCGCCGCCA CCGCTGCGGC TGCCGCTGCT GCTGCTGGTG 
CTGGCGGCGG TGACCGGCCA CACGGCCGCG CAGGACAACT GCACGTGTCC CACCAACAAG 
ATGACCGTGT GCAGCCCCGA CGGCCCCGGC GGCCGCTGCC AGTGCCGCGC GCTGGGCTCG 
GGCATGGCGG TCGACTGCTC CACGCTGACC TCCAAGTGTC TGCTGCTCAA GGCGCGCATG 
AGCGCCCCCA AGAACGCCCG CACGCTGGTG CGGCCGAGTG AGCACGCGCT CGTGGACAAC 
GATGGCCTCT ACGACCCCGA CTGCGACCCC GAGGGCCGCT TCAAGGCGCG CCAGTGCAAC 
CAGACGTCGG TGTGCTGGTG CGTGAACTCG GTGGGCGTGC GCCGCACGGA CAAGGGCGAC 
CTGAGCCTAC GCTGCGATGA GCTGGTGCGC ACCCACCACA TCCTCATTGA CCTGCGCCAC 
CGCCCCACCG CCGGCGCCTT CAACCACTCA GACCTGGACG CCGAGCTGAG GCGGCTCTTC 
CGCGAGCGCT ATCGGCTGCA CCCCAAGTTC GTGGCGGCCG TGCACTACGA GCAGCCCACC 
ATCCAGATCG AGCTGCGGCA GAACACGTCT CAGAAGGCCG CCGGTGACGT GGATATCGGC 
GATGCCGCCT ACTACTTCGA GAGGGACATC AAGGGCGAGT CTCTATTCCA GGGCCGCGGC 
GGCCTGGACT TGCGCGTGCG CGGAGAACCC CTGCAGGTGG AGCGCACGCT CATCTATTAC 
CTGGACGAGA TTCCCCCGAA GTTCTCCATG AAGCGCCTCA CCGCCGGCCT CATCGCCGTC 
ATCGTGGTGG TCGTGGTGGC CCTCGTCGCC GGCATGGCCG TCCTGGTGAT CACCAACCGG 
AGAAAGTCGG GGAAGTACAA GAAGGTGGAG ATCAAGGAAC TGGGGGAGTT GAGAAAGGAA 
CCGAGCTTGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization.
Cytogenetics and cell genetics92(1-2)164-5(2001)
Calabrese G,Crescenzi C,Morizio E,Palka G,Guerra E,Alberti S

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

TACSTD2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報