LPO cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LPO
Entrez Gene ID	4025
Full Name	lactoperoxidase
Synonyms	SPO
General protein information	Preferred Names lactoperoxidase Names lactoperoxidase salivary peroxidase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q22
Summary	This gene encodes a member of the peroxidase family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Following its secretion from salivary, mammary, and other mucosal glands, this enzyme catalyzes the generation of the antimicrobial substance hypothiocyanous acid. This gene is present in a gene cluster on chromosome 17. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016].
Disorder MIM:	150205

mRNA and Protein(s)

mRNA	Protein	Name
NM_006151.2	NP_006142.1	lactoperoxidase isoform 1 preproprotein
NM_006151.3	NP_006142.1	lactoperoxidase isoform 1 preproprotein
XM_011524808.2	XP_011523110.1	lactoperoxidase isoform X1
XM_011524810.2	XP_011523112.1	lactoperoxidase isoform X2
NM_001160102.1	NP_001153574.1	lactoperoxidase isoform 3 preproprotein

Pathways from BioSystems

Homologies

Homo sapiens (human)	LPO	NP_006142.1
	LPO	XP_001106438.1
Pan troglodytes (chimpanzee)	LPO	XP_003315682.1
Rattus norvegicus (Norway rat)	Lpo	NP_001099299.1
Canis lupus familiaris (dog)	LPO	XP_548231.3
Bos taurus (cattle)	LPO	NP_776358.1
Mus musculus (house mouse)	Lpo	NP_536345.2

Gene Ontology
Bibliography

Related articles in PubMed

Design of anti-thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2-mercaptoimidazole at 2.30 ? resolution.
Sirohi HV, Singh PK, Iqbal N, Sharma P, Singh AK, Kaur P, Sharma S, Singh TP
Proteins85(10)1882-1890(2017 Oct)

The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H. pylori.
Li H, Zhou Y, Zheng Y, Guo H, Gao L, Chen P, Feng D, Wu L, Yang M, Qi Y, Guo H, Chang Y, Chu FF, Gao Q
Digestive diseases and sciences61(8)2328-37(2016 08)

Uric acid and thiocyanate as competing substrates of lactoperoxidase.
Seidel A, Parker H, Turner R, Dickerhof N, Khalilova IS, Wilbanks SM, Kettle AJ, Jameson GN
The Journal of biological chemistry289(32)21937-49(2014 Aug)

The assessment of sIgA, histatin-5, and lactoperoxidase levels in saliva of adolescents with dental caries.
Gornowicz A, Tokajuk G, Bielawska A, Maciorkowska E, Jab?o?ski R, W?jcicka A, Bielawski K
Medical science monitor : international medical journal of experimental and clinical research201095-100(2014 Jun)

The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17.
Sakamaki K, Kanda N, Ueda T, Aikawa E, Nagata S
Cytogenetics and cell genetics88(3-4)246-8(2000)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The crystal structure of the complex of LPO with MZY showed that MZY bound to LPO in the substrate-binding site on the distal heme side. MZY was oriented in the substrate-binding site in such a way that the sulfur atom is at a distance of 2.58 A from the heme iron
Title: Design of anti-thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2-mercaptoimidazole at 2.30 ? resolution.

LPO mRNA was undetectable in the gastric mucosa.
Title: The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H. pylori.

establish urate as a likely physiological substrate for LPO that will influence host defense and give rise to reactive electrophilic metabolites
Title: Uric acid and thiocyanate as competing substrates of lactoperoxidase.

High intensity of caries is associated with increased levels of some salivary components - sIgA, histatin-5 and lactoperoxidase.
Title: The assessment of sIgA, histatin-5, and lactoperoxidase levels in saliva of adolescents with dental caries.

Oral peroxidase activity as a marker of chronic alcohol abuse may help in the diagnosis of alcoholism.
Title: The effect of chronic alcohol intoxication and smoking on the activity of oral peroxidase.

The following LPO gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LPO cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03090	NM_001160102.1 Latest version!	Homo sapiens lactoperoxidase (LPO), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05404	NM_006151.3 Latest version!	Homo sapiens lactoperoxidase (LPO), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu58763	XM_011524808.2 Latest version!	Homo sapiens lactoperoxidase (LPO), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu58765	XM_011524810.2 Latest version!	Homo sapiens lactoperoxidase (LPO), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu05404	NM_006151.2	Homo sapiens lactoperoxidase (LPO), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LPO ( NM_001160102.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153574.1 Homo sapiens lactoperoxidase (LPO), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu03090
Clone ID Related Accession (Same CDS sequence)	NM_001160102.1
Accession Version	NM_001160102.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1890bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	lactoperoxidase isoform 3 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB230339.1, EF579964.1, U39573.1 and M58151.1. Transcript Variant: This variant (3) lacks two alternate exons in the 5' coding region, compared to variant 1. The resulting isoform (3) lacks an internal segment near the N-terminus, compared to isoform 1. This isoform is thought to be secreted but the sites of proteolytic processing have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF579964.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2150585 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGGTCC TTCTCCATCT CCCAGCCCTC CTGGCTTCCC TCATCTTGCT TCAGGCTGCA 
GCATCTACCA CAAGAGATCC CAGCCTGGAC TTGACTTCAC TGTCTCTGGA GGTGGGCTGT 
GGTGCTCCTG CTCCCGTGGT GAGATGCGAC CCGTGCAGCC CTTACCGCAC CATTACGGGA 
GACTGCAATA ACAGGAGGAA GCCTGCGCTG GGCGCCGCCA ACAGGGCTCT GGCGCGCTGG 
CTGCCCGCGG AGTACGAGGA CGGGCTCTCC CTGCCCTTCG GCTGGACGCC GGGGAAGACG 
CGCAACGGCT TCCCTCTCCC GCTGGCCCGG GAGGTATCTA ACAAGATTGT TGGCTATCTG 
AATGAGGAGG GTGTTCTGGA CCAAAACAGG TCCCTGCTCT TCATGCAGTG GGGTCAGATT 
GTGGATCATG ACCTGGACTT TGCCCCTGAC ACCGAGCTGG GGAGTAGCGA GTACTCCAAA 
GCCCAGTGTG ATGAGTACTG TATCCAGGGA GACAACTGCT TCCCCATCAT GTTCCCACCC 
AATGACCCCA AGGCGGGGAC TCAAGGGAAA TGCATGCCTT TCTTCCGAGC TGGGTTCGTC 
TGCCCCACTC CACCCTACAA GTCCCTGGCC CGAGAGCAGA TCAACGCTCT GACCTCCTTC 
CTGGATGCCA GCTTTGTGTA CAGCTCCGAG CCAAGCCTGG CCAGCCGCCT CCGCAACCTC 
AGCAGCCCCC TGGGCCTCAT GGCTGTCAAC CAGGAGGTCT CAGACCATGG ACTACCCTAC 
CTGCCCTATG ACAGCAAGAA GCCAAGCCCC TGTGAGTTCA TCAACACCAC TGCCCGTGTG 
CCCTGCTTCC TGGCAGGAGA TTCTCGAGCC TCAGAGCATA TTCTGCTGGC CACATCCCAC 
ACCCTCTTTC TCCGCGAGCA TAACCGGCTG GCCAGAGAAC TAAAGAGACT CAACCCTCAG 
TGGGATGGAG AGAAGCTCTA CCAGGAAGCC CGGAAAATCC TGGGAGCCTT CGTGCAGATT 
ATCACCTTTA GGGACTACCT ACCCATTTTG CTAGGTGACC ACATGCAGAA GTGGATACCC 
CCATATCAAG GCTACAGTGA ATCTGTGGAT CCCAGAATTT CCAATGTCTT CACCTTCGCC 
TTCCGCTTTG GCCACTTGGA GGTCCCCTCT AGTATGTTCC GCCTGGATGA GAATTATCAG 
CCATGGGGGC CAGAACCAGA ACTCCCCCTC CACACCCTCT TCTTCAACAC TTGGAGGATG 
GTCAAAGATG GTGGAATTGA TCCTCTGGTG CGGGGCCTGC TGGCCAAGAA ATCCAAGCTG 
ATGAAACAGA ATAAAATGAT GACTGGAGAG CTGCGCAACA AGCTTTTCCA GCCAACTCAC 
AGGATCCATG GCTTTGACCT GGCTGCCATC AACACACAGC GTTGCCGGGA CCATGGGCAA 
CCTGGGTACA ATTCCTGGAG AGCCTTCTGT GACCTCTCAC AGCCGCAGAC ACTAGAGGAG 
TTGAACACAG TGCTGAAGAG CAAGATGCTG GCCAAGAAGT TACTGGGTCT CTACGGGACC 
CCTGACAACA TCGACATCTG GATAGGGGCC ATTGCTGAGC CGCTGGTGGA AAGGGGTCGG 
GTGGGGCCTC TCCTGGCCTG CCTCTTGGGC AAGCAGTTCC AGCAGATCCG TGATGGAGAC 
AGGTTCTGGT GGGAAAACCC TGGGGTCTTC ACGAACGAGC AGAAGGACTC TCTACAGAAA 
ATGTCCTTCT CACGCCTTGT CTGTGACAAC ACCCGCATCA CCAAGGTCCC ACGGGACCCA 
TTCTGGGCCA ACAGCTACCC CTATGACTTC GTGGATTGCT CAGCCATCGA CAAGCTGGAC 
CTGTCACCCT GGGCCTCAGT GAAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153574.1
CDS	317..2206
Translation	MRVLLHLPALLASLILLQAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN

Target ORF information:

RefSeq Version	NM_001160102.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lactoperoxidase (LPO), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001160102.1

ORF Insert Sequence:

ATGAGGGTCC TTCTCCATCT CCCAGCCCTC CTGGCTTCCC TCATCTTGCT TCAGGCTGCA 
GCATCTACCA CAAGAGATCC CAGCCTGGAC TTGACTTCAC TGTCTCTGGA GGTGGGCTGT 
GGTGCTCCTG CTCCCGTGGT GAGATGCGAC CCGTGCAGCC CTTACCGCAC CATTACGGGA 
GACTGCAATA ACAGGAGGAA GCCTGCGCTG GGCGCCGCCA ACAGGGCTCT GGCGCGCTGG 
CTGCCCGCGG AGTACGAGGA CGGGCTCTCC CTGCCCTTCG GCTGGACGCC GGGGAAGACG 
CGCAACGGCT TCCCTCTCCC GCTGGCCCGG GAGGTATCTA ACAAGATTGT TGGCTATCTG 
AATGAGGAGG GTGTTCTGGA CCAAAACAGG TCCCTGCTCT TCATGCAGTG GGGTCAGATT 
GTGGATCATG ACCTGGACTT TGCCCCTGAC ACCGAGCTGG GGAGTAGCGA GTACTCCAAA 
GCCCAGTGTG ATGAGTACTG TATCCAGGGA GACAACTGCT TCCCCATCAT GTTCCCACCC 
AATGACCCCA AGGCGGGGAC TCAAGGGAAA TGCATGCCTT TCTTCCGAGC TGGGTTCGTC 
TGCCCCACTC CACCCTACAA GTCCCTGGCC CGAGAGCAGA TCAACGCTCT GACCTCCTTC 
CTGGATGCCA GCTTTGTGTA CAGCTCCGAG CCAAGCCTGG CCAGCCGCCT CCGCAACCTC 
AGCAGCCCCC TGGGCCTCAT GGCTGTCAAC CAGGAGGTCT CAGACCATGG ACTACCCTAC 
CTGCCCTATG ACAGCAAGAA GCCAAGCCCC TGTGAGTTCA TCAACACCAC TGCCCGTGTG 
CCCTGCTTCC TGGCAGGAGA TTCTCGAGCC TCAGAGCATA TTCTGCTGGC CACATCCCAC 
ACCCTCTTTC TCCGCGAGCA TAACCGGCTG GCCAGAGAAC TAAAGAGACT CAACCCTCAG 
TGGGATGGAG AGAAGCTCTA CCAGGAAGCC CGGAAAATCC TGGGAGCCTT CGTGCAGATT 
ATCACCTTTA GGGACTACCT ACCCATTTTG CTAGGTGACC ACATGCAGAA GTGGATACCC 
CCATATCAAG GCTACAGTGA ATCTGTGGAT CCCAGAATTT CCAATGTCTT CACCTTCGCC 
TTCCGCTTTG GCCACTTGGA GGTCCCCTCT AGTATGTTCC GCCTGGATGA GAATTATCAG 
CCATGGGGGC CAGAACCAGA ACTCCCCCTC CACACCCTCT TCTTCAACAC TTGGAGGATG 
GTCAAAGATG GTGGAATTGA TCCTCTGGTG CGGGGCCTGC TGGCCAAGAA ATCCAAGCTG 
ATGAAACAGA ATAAAATGAT GACTGGAGAG CTGCGCAACA AGCTTTTCCA GCCAACTCAC 
AGGATCCATG GCTTTGACCT GGCTGCCATC AACACACAGC GTTGCCGGGA CCATGGGCAA 
CCTGGGTACA ATTCCTGGAG AGCCTTCTGT GACCTCTCAC AGCCGCAGAC ACTAGAGGAG 
TTGAACACAG TGCTGAAGAG CAAGATGCTG GCCAAGAAGT TACTGGGTCT CTACGGGACC 
CCTGACAACA TCGACATCTG GATAGGGGCC ATTGCTGAGC CGCTGGTGGA AAGGGGTCGG 
GTGGGGCCTC TCCTGGCCTG CCTCTTGGGC AAGCAGTTCC AGCAGATCCG TGATGGAGAC 
AGGTTCTGGT GGGAAAACCC TGGGGTCTTC ACGAACGAGC AGAAGGACTC TCTACAGAAA 
ATGTCCTTCT CACGCCTTGT CTGTGACAAC ACCCGCATCA CCAAGGTCCC ACGGGACCCA 
TTCTGGGCCA ACAGCTACCC CTATGACTTC GTGGATTGCT CAGCCATCGA CAAGCTGGAC 
CTGTCACCCT GGGCCTCAGT GAAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LPO ( NM_006151.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006142.1 Homo sapiens lactoperoxidase (LPO), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05404
Clone ID Related Accession (Same CDS sequence)	NM_006151.2 , NM_006151.3
Accession Version	NM_006151.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2139bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	lactoperoxidase isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB230339.1, BC107166.1, U39573.1 and M58151.1. On May 12, 2009 this sequence version replaced NM_006151.1. Transcript Variant: This variant (1) represents the longest and predominant transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U39573.1, BX648309.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGGTCC TTCTCCATCT CCCAGCCCTC CTGGCTTCCC TCATCTTGCT TCAGGCTGCA 
GCATCTACCA CAAGAGCGCA GACTACCAGA ACCTCTGCCA TCTCCGATAC TGTGAGTCAG 
GCCAAGGTCC AAGTCAACAA GGCCTTCCTG GACTCCCGAA CCAGGCTGAA GACCGCCATG 
AGCTCTGAGA CTCCCACCAG CCGACAGCTC TCAGAATACC TCAAGCATGC CAAAGGCCGG 
ACGCGCACAG CCATCCGCAA TGGACAGGTG TGGGAGGAGT CTTTAAAGAG ACTGAGGCAG 
AAGGCATCCT TGACCAATGT CACAGATCCC AGCCTGGACT TGACTTCACT GTCTCTGGAG 
GTGGGCTGTG GTGCTCCTGC TCCCGTGGTG AGATGCGACC CGTGCAGCCC TTACCGCACC 
ATTACGGGAG ACTGCAATAA CAGGAGGAAG CCTGCGCTGG GCGCCGCCAA CAGGGCTCTG 
GCGCGCTGGC TGCCCGCGGA GTACGAGGAC GGGCTCTCCC TGCCCTTCGG CTGGACGCCG 
GGGAAGACGC GCAACGGCTT CCCTCTCCCG CTGGCCCGGG AGGTATCTAA CAAGATTGTT 
GGCTATCTGA ATGAGGAGGG TGTTCTGGAC CAAAACAGGT CCCTGCTCTT CATGCAGTGG 
GGTCAGATTG TGGATCATGA CCTGGACTTT GCCCCTGACA CCGAGCTGGG GAGTAGCGAG 
TACTCCAAAG CCCAGTGTGA TGAGTACTGT ATCCAGGGAG ACAACTGCTT CCCCATCATG 
TTCCCACCCA ATGACCCCAA GGCGGGGACT CAAGGGAAAT GCATGCCTTT CTTCCGAGCT 
GGGTTCGTCT GCCCCACTCC ACCCTACAAG TCCCTGGCCC GAGAGCAGAT CAACGCTCTG 
ACCTCCTTCC TGGATGCCAG CTTTGTGTAC AGCTCCGAGC CAAGCCTGGC CAGCCGCCTC 
CGCAACCTCA GCAGCCCCCT GGGCCTCATG GCTGTCAACC AGGAGGTCTC AGACCATGGA 
CTACCCTACC TGCCCTATGA CAGCAAGAAG CCAAGCCCCT GTGAGTTCAT CAACACCACT 
GCCCGTGTGC CCTGCTTCCT GGCAGGAGAT TCTCGAGCCT CAGAGCATAT TCTGCTGGCC 
ACATCCCACA CCCTCTTTCT CCGCGAGCAT AACCGGCTGG CCAGAGAACT AAAGAGACTC 
AACCCTCAGT GGGATGGAGA GAAGCTCTAC CAGGAAGCCC GGAAAATCCT GGGAGCCTTC 
GTGCAGATTA TCACCTTTAG GGACTACCTA CCCATTTTGC TAGGTGACCA CATGCAGAAG 
TGGATACCCC CATATCAAGG CTACAGTGAA TCTGTGGATC CCAGAATTTC CAATGTCTTC 
ACCTTCGCCT TCCGCTTTGG CCACTTGGAG GTCCCCTCTA GTATGTTCCG CCTGGATGAG 
AATTATCAGC CATGGGGGCC AGAACCAGAA CTCCCCCTCC ACACCCTCTT CTTCAACACT 
TGGAGGATGG TCAAAGATGG TGGAATTGAT CCTCTGGTGC GGGGCCTGCT GGCCAAGAAA 
TCCAAGCTGA TGAAACAGAA TAAAATGATG ACTGGAGAGC TGCGCAACAA GCTTTTCCAG 
CCAACTCACA GGATCCATGG CTTTGACCTG GCTGCCATCA ACACACAGCG TTGCCGGGAC 
CATGGGCAAC CTGGGTACAA TTCCTGGAGA GCCTTCTGTG ACCTCTCACA GCCGCAGACA 
CTAGAGGAGT TGAACACAGT GCTGAAGAGC AAGATGCTGG CCAAGAAGTT ACTGGGTCTC 
TACGGGACCC CTGACAACAT CGACATCTGG ATAGGGGCCA TTGCTGAGCC GCTGGTGGAA 
AGGGGTCGGG TGGGGCCTCT CCTGGCCTGC CTCTTGGGCA AGCAGTTCCA GCAGATCCGT 
GATGGAGACA GGTTCTGGTG GGAAAACCCT GGGGTCTTCA CGAACGAGCA GAAGGACTCT 
CTACAGAAAA TGTCCTTCTC ACGCCTTGTC TGTGACAACA CCCGCATCAC CAAGGTCCCA 
CGGGACCCAT TCTGGGCCAA CAGCTACCCC TATGACTTCG TGGATTGCTC AGCCATCGAC 
AAGCTGGACC TGTCACCCTG GGCCTCAGTG AAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006142.1
CDS	317..2455
Translation	MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN

Target ORF information:

RefSeq Version	NM_006151.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lactoperoxidase (LPO), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006151.2

ORF Insert Sequence:

ATGAGGGTCC TTCTCCATCT CCCAGCCCTC CTGGCTTCCC TCATCTTGCT TCAGGCTGCA 
GCATCTACCA CAAGAGCGCA GACTACCAGA ACCTCTGCCA TCTCCGATAC TGTGAGTCAG 
GCCAAGGTCC AAGTCAACAA GGCCTTCCTG GACTCCCGAA CCAGGCTGAA GACCGCCATG 
AGCTCTGAGA CTCCCACCAG CCGACAGCTC TCAGAATACC TCAAGCATGC CAAAGGCCGG 
ACGCGCACAG CCATCCGCAA TGGACAGGTG TGGGAGGAGT CTTTAAAGAG ACTGAGGCAG 
AAGGCATCCT TGACCAATGT CACAGATCCC AGCCTGGACT TGACTTCACT GTCTCTGGAG 
GTGGGCTGTG GTGCTCCTGC TCCCGTGGTG AGATGCGACC CGTGCAGCCC TTACCGCACC 
ATTACGGGAG ACTGCAATAA CAGGAGGAAG CCTGCGCTGG GCGCCGCCAA CAGGGCTCTG 
GCGCGCTGGC TGCCCGCGGA GTACGAGGAC GGGCTCTCCC TGCCCTTCGG CTGGACGCCG 
GGGAAGACGC GCAACGGCTT CCCTCTCCCG CTGGCCCGGG AGGTATCTAA CAAGATTGTT 
GGCTATCTGA ATGAGGAGGG TGTTCTGGAC CAAAACAGGT CCCTGCTCTT CATGCAGTGG 
GGTCAGATTG TGGATCATGA CCTGGACTTT GCCCCTGACA CCGAGCTGGG GAGTAGCGAG 
TACTCCAAAG CCCAGTGTGA TGAGTACTGT ATCCAGGGAG ACAACTGCTT CCCCATCATG 
TTCCCACCCA ATGACCCCAA GGCGGGGACT CAAGGGAAAT GCATGCCTTT CTTCCGAGCT 
GGGTTCGTCT GCCCCACTCC ACCCTACAAG TCCCTGGCCC GAGAGCAGAT CAACGCTCTG 
ACCTCCTTCC TGGATGCCAG CTTTGTGTAC AGCTCCGAGC CAAGCCTGGC CAGCCGCCTC 
CGCAACCTCA GCAGCCCCCT GGGCCTCATG GCTGTCAACC AGGAGGTCTC AGACCATGGA 
CTACCCTACC TGCCCTATGA CAGCAAGAAG CCAAGCCCCT GTGAGTTCAT CAACACCACT 
GCCCGTGTGC CCTGCTTCCT GGCAGGAGAT TCTCGAGCCT CAGAGCATAT TCTGCTGGCC 
ACATCCCACA CCCTCTTTCT CCGCGAGCAT AACCGGCTGG CCAGAGAACT AAAGAGACTC 
AACCCTCAGT GGGATGGAGA GAAGCTCTAC CAGGAAGCCC GGAAAATCCT GGGAGCCTTC 
GTGCAGATTA TCACCTTTAG GGACTACCTA CCCATTTTGC TAGGTGACCA CATGCAGAAG 
TGGATACCCC CATATCAAGG CTACAGTGAA TCTGTGGATC CCAGAATTTC CAATGTCTTC 
ACCTTCGCCT TCCGCTTTGG CCACTTGGAG GTCCCCTCTA GTATGTTCCG CCTGGATGAG 
AATTATCAGC CATGGGGGCC AGAACCAGAA CTCCCCCTCC ACACCCTCTT CTTCAACACT 
TGGAGGATGG TCAAAGATGG TGGAATTGAT CCTCTGGTGC GGGGCCTGCT GGCCAAGAAA 
TCCAAGCTGA TGAAACAGAA TAAAATGATG ACTGGAGAGC TGCGCAACAA GCTTTTCCAG 
CCAACTCACA GGATCCATGG CTTTGACCTG GCTGCCATCA ACACACAGCG TTGCCGGGAC 
CATGGGCAAC CTGGGTACAA TTCCTGGAGA GCCTTCTGTG ACCTCTCACA GCCGCAGACA 
CTAGAGGAGT TGAACACAGT GCTGAAGAGC AAGATGCTGG CCAAGAAGTT ACTGGGTCTC 
TACGGGACCC CTGACAACAT CGACATCTGG ATAGGGGCCA TTGCTGAGCC GCTGGTGGAA 
AGGGGTCGGG TGGGGCCTCT CCTGGCCTGC CTCTTGGGCA AGCAGTTCCA GCAGATCCGT 
GATGGAGACA GGTTCTGGTG GGAAAACCCT GGGGTCTTCA CGAACGAGCA GAAGGACTCT 
CTACAGAAAA TGTCCTTCTC ACGCCTTGTC TGTGACAACA CCCGCATCAC CAAGGTCCCA 
CGGGACCCAT TCTGGGCCAA CAGCTACCCC TATGACTTCG TGGATTGCTC AGCCATCGAC 
AAGCTGGACC TGTCACCCTG GGCCTCAGTG AAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LPO ( NM_006151.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006142.1 Homo sapiens lactoperoxidase (LPO), transcript variant 1, mRNA.

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CloneID	OHu05404
Clone ID Related Accession (Same CDS sequence)	NM_006151.2 , NM_006151.3
Accession Version	NM_006151.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2139bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	lactoperoxidase isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC107166.1, U39573.1 and M58151.1. On May 17, 2019 this sequence version replaced NM_006151.2. Transcript Variant: This variant (1) represents the longest and predominant transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U39573.1, BX648309.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000262290.9/ ENSP00000262290.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGGTCC TTCTCCATCT CCCAGCCCTC CTGGCTTCCC TCATCTTGCT TCAGGCTGCA 
GCATCTACCA CAAGAGCGCA GACTACCAGA ACCTCTGCCA TCTCCGATAC TGTGAGTCAG 
GCCAAGGTCC AAGTCAACAA GGCCTTCCTG GACTCCCGAA CCAGGCTGAA GACCGCCATG 
AGCTCTGAGA CTCCCACCAG CCGACAGCTC TCAGAATACC TCAAGCATGC CAAAGGCCGG 
ACGCGCACAG CCATCCGCAA TGGACAGGTG TGGGAGGAGT CTTTAAAGAG ACTGAGGCAG 
AAGGCATCCT TGACCAATGT CACAGATCCC AGCCTGGACT TGACTTCACT GTCTCTGGAG 
GTGGGCTGTG GTGCTCCTGC TCCCGTGGTG AGATGCGACC CGTGCAGCCC TTACCGCACC 
ATTACGGGAG ACTGCAATAA CAGGAGGAAG CCTGCGCTGG GCGCCGCCAA CAGGGCTCTG 
GCGCGCTGGC TGCCCGCGGA GTACGAGGAC GGGCTCTCCC TGCCCTTCGG CTGGACGCCG 
GGGAAGACGC GCAACGGCTT CCCTCTCCCG CTGGCCCGGG AGGTATCTAA CAAGATTGTT 
GGCTATCTGA ATGAGGAGGG TGTTCTGGAC CAAAACAGGT CCCTGCTCTT CATGCAGTGG 
GGTCAGATTG TGGATCATGA CCTGGACTTT GCCCCTGACA CCGAGCTGGG GAGTAGCGAG 
TACTCCAAAG CCCAGTGTGA TGAGTACTGT ATCCAGGGAG ACAACTGCTT CCCCATCATG 
TTCCCACCCA ATGACCCCAA GGCGGGGACT CAAGGGAAAT GCATGCCTTT CTTCCGAGCT 
GGGTTCGTCT GCCCCACTCC ACCCTACAAG TCCCTGGCCC GAGAGCAGAT CAACGCTCTG 
ACCTCCTTCC TGGATGCCAG CTTTGTGTAC AGCTCCGAGC CAAGCCTGGC CAGCCGCCTC 
CGCAACCTCA GCAGCCCCCT GGGCCTCATG GCTGTCAACC AGGAGGTCTC AGACCATGGA 
CTACCCTACC TGCCCTATGA CAGCAAGAAG CCAAGCCCCT GTGAGTTCAT CAACACCACT 
GCCCGTGTGC CCTGCTTCCT GGCAGGAGAT TCTCGAGCCT CAGAGCATAT TCTGCTGGCC 
ACATCCCACA CCCTCTTTCT CCGCGAGCAT AACCGGCTGG CCAGAGAACT AAAGAGACTC 
AACCCTCAGT GGGATGGAGA GAAGCTCTAC CAGGAAGCCC GGAAAATCCT GGGAGCCTTC 
GTGCAGATTA TCACCTTTAG GGACTACCTA CCCATTTTGC TAGGTGACCA CATGCAGAAG 
TGGATACCCC CATATCAAGG CTACAGTGAA TCTGTGGATC CCAGAATTTC CAATGTCTTC 
ACCTTCGCCT TCCGCTTTGG CCACTTGGAG GTCCCCTCTA GTATGTTCCG CCTGGATGAG 
AATTATCAGC CATGGGGGCC AGAACCAGAA CTCCCCCTCC ACACCCTCTT CTTCAACACT 
TGGAGGATGG TCAAAGATGG TGGAATTGAT CCTCTGGTGC GGGGCCTGCT GGCCAAGAAA 
TCCAAGCTGA TGAAACAGAA TAAAATGATG ACTGGAGAGC TGCGCAACAA GCTTTTCCAG 
CCAACTCACA GGATCCATGG CTTTGACCTG GCTGCCATCA ACACACAGCG TTGCCGGGAC 
CATGGGCAAC CTGGGTACAA TTCCTGGAGA GCCTTCTGTG ACCTCTCACA GCCGCAGACA 
CTAGAGGAGT TGAACACAGT GCTGAAGAGC AAGATGCTGG CCAAGAAGTT ACTGGGTCTC 
TACGGGACCC CTGACAACAT CGACATCTGG ATAGGGGCCA TTGCTGAGCC GCTGGTGGAA 
AGGGGTCGGG TGGGGCCTCT CCTGGCCTGC CTCTTGGGCA AGCAGTTCCA GCAGATCCGT 
GATGGAGACA GGTTCTGGTG GGAAAACCCT GGGGTCTTCA CGAACGAGCA GAAGGACTCT 
CTACAGAAAA TGTCCTTCTC ACGCCTTGTC TGTGACAACA CCCGCATCAC CAAGGTCCCA 
CGGGACCCAT TCTGGGCCAA CAGCTACCCC TATGACTTCG TGGATTGCTC AGCCATCGAC 
AAGCTGGACC TGTCACCCTG GGCCTCAGTG AAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006142.1
CDS	159..2297
Translation	MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN

Target ORF information:

RefSeq Version	NM_006151.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lactoperoxidase (LPO), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006151.3

ORF Insert Sequence:

ATGAGGGTCC TTCTCCATCT CCCAGCCCTC CTGGCTTCCC TCATCTTGCT TCAGGCTGCA 
GCATCTACCA CAAGAGCGCA GACTACCAGA ACCTCTGCCA TCTCCGATAC TGTGAGTCAG 
GCCAAGGTCC AAGTCAACAA GGCCTTCCTG GACTCCCGAA CCAGGCTGAA GACCGCCATG 
AGCTCTGAGA CTCCCACCAG CCGACAGCTC TCAGAATACC TCAAGCATGC CAAAGGCCGG 
ACGCGCACAG CCATCCGCAA TGGACAGGTG TGGGAGGAGT CTTTAAAGAG ACTGAGGCAG 
AAGGCATCCT TGACCAATGT CACAGATCCC AGCCTGGACT TGACTTCACT GTCTCTGGAG 
GTGGGCTGTG GTGCTCCTGC TCCCGTGGTG AGATGCGACC CGTGCAGCCC TTACCGCACC 
ATTACGGGAG ACTGCAATAA CAGGAGGAAG CCTGCGCTGG GCGCCGCCAA CAGGGCTCTG 
GCGCGCTGGC TGCCCGCGGA GTACGAGGAC GGGCTCTCCC TGCCCTTCGG CTGGACGCCG 
GGGAAGACGC GCAACGGCTT CCCTCTCCCG CTGGCCCGGG AGGTATCTAA CAAGATTGTT 
GGCTATCTGA ATGAGGAGGG TGTTCTGGAC CAAAACAGGT CCCTGCTCTT CATGCAGTGG 
GGTCAGATTG TGGATCATGA CCTGGACTTT GCCCCTGACA CCGAGCTGGG GAGTAGCGAG 
TACTCCAAAG CCCAGTGTGA TGAGTACTGT ATCCAGGGAG ACAACTGCTT CCCCATCATG 
TTCCCACCCA ATGACCCCAA GGCGGGGACT CAAGGGAAAT GCATGCCTTT CTTCCGAGCT 
GGGTTCGTCT GCCCCACTCC ACCCTACAAG TCCCTGGCCC GAGAGCAGAT CAACGCTCTG 
ACCTCCTTCC TGGATGCCAG CTTTGTGTAC AGCTCCGAGC CAAGCCTGGC CAGCCGCCTC 
CGCAACCTCA GCAGCCCCCT GGGCCTCATG GCTGTCAACC AGGAGGTCTC AGACCATGGA 
CTACCCTACC TGCCCTATGA CAGCAAGAAG CCAAGCCCCT GTGAGTTCAT CAACACCACT 
GCCCGTGTGC CCTGCTTCCT GGCAGGAGAT TCTCGAGCCT CAGAGCATAT TCTGCTGGCC 
ACATCCCACA CCCTCTTTCT CCGCGAGCAT AACCGGCTGG CCAGAGAACT AAAGAGACTC 
AACCCTCAGT GGGATGGAGA GAAGCTCTAC CAGGAAGCCC GGAAAATCCT GGGAGCCTTC 
GTGCAGATTA TCACCTTTAG GGACTACCTA CCCATTTTGC TAGGTGACCA CATGCAGAAG 
TGGATACCCC CATATCAAGG CTACAGTGAA TCTGTGGATC CCAGAATTTC CAATGTCTTC 
ACCTTCGCCT TCCGCTTTGG CCACTTGGAG GTCCCCTCTA GTATGTTCCG CCTGGATGAG 
AATTATCAGC CATGGGGGCC AGAACCAGAA CTCCCCCTCC ACACCCTCTT CTTCAACACT 
TGGAGGATGG TCAAAGATGG TGGAATTGAT CCTCTGGTGC GGGGCCTGCT GGCCAAGAAA 
TCCAAGCTGA TGAAACAGAA TAAAATGATG ACTGGAGAGC TGCGCAACAA GCTTTTCCAG 
CCAACTCACA GGATCCATGG CTTTGACCTG GCTGCCATCA ACACACAGCG TTGCCGGGAC 
CATGGGCAAC CTGGGTACAA TTCCTGGAGA GCCTTCTGTG ACCTCTCACA GCCGCAGACA 
CTAGAGGAGT TGAACACAGT GCTGAAGAGC AAGATGCTGG CCAAGAAGTT ACTGGGTCTC 
TACGGGACCC CTGACAACAT CGACATCTGG ATAGGGGCCA TTGCTGAGCC GCTGGTGGAA 
AGGGGTCGGG TGGGGCCTCT CCTGGCCTGC CTCTTGGGCA AGCAGTTCCA GCAGATCCGT 
GATGGAGACA GGTTCTGGTG GGAAAACCCT GGGGTCTTCA CGAACGAGCA GAAGGACTCT 
CTACAGAAAA TGTCCTTCTC ACGCCTTGTC TGTGACAACA CCCGCATCAC CAAGGTCCCA 
CGGGACCCAT TCTGGGCCAA CAGCTACCCC TATGACTTCG TGGATTGCTC AGCCATCGAC 
AAGCTGGACC TGTCACCCTG GGCCTCAGTG AAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LPO ( XM_011524808.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011523110.1 Homo sapiens lactoperoxidase (LPO), transcript variant X1, mRNA.

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CloneID	OHu58763
Clone ID Related Accession (Same CDS sequence)	XM_011524808.2
Accession Version	XM_011524808.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lactoperoxidase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524808.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGGTCC TTCTCCATCT CCCAGCCCTC CTGGCTTCCC TCATCTTGCT TCAGGCTGCA 
GCATCTACCA CAAGAGCGCA GACTACCAGA ACCTCTGCCA TCTCCGATAC TGTGAGTCAG 
GCCAAGGTCC AAGTCAACAA GGCCTTCCTG GACTCCCGAA CCAGGCTGAA GACCGCCATG 
AGCTCTGAGA CTCCCACCAG CCGACAGCTC TCAGAATACC TCAAGCATGC CAAAGGCCGG 
ACGCGCACAG CCATCCGCAA TGGACAGGTG TGGGAGGAGT CTTTAAAGAG ACTGAGGCAG 
AAGGCATCCT TGACCAATGT CACAGATCCC AGCCTGGACT TGACTTCACT GTCTCTGGAG 
GTGGGCTGTG GTGCTCCTGC TCCCGTGGTG AGATGCGACC CGTGCAGCCC TTACCGCACC 
ATTACGGGAG ACTGCAATAA CAGGAGGAAG CCTGCGCTGG GCGCCGCCAA CAGGGCTCTG 
GCGCGCTGGC TGCCCGCGGA GTACGAGGAC GGGCTCTCCC TGCCCTTCGG CTGGACGCCG 
GGGAAGACGC GCAACGGCTT CCCTCTCCCG CTGGCCCGGG AGGTATCTAA CAAGATTGTT 
GGCTATCTGA ATGAGGAGGG TGTTCTGGAC CAAAACAGGT CCCTGCTCTT CATGCAGTGG 
GGTCAGATTG TGGATCATGA CCTGGACTTT GCCCCTGACA CCGAGCTGGG GAGTAGCGAG 
TACTCCAAAG CCCAGTGTGA TGAGTACTGT ATCCAGGGAG ACAACTGCTT CCCCATCATG 
TTCCCACCCA ATGACCCCAA GGCGGGGACT CAAGGGAAAT GCATGCCTTT CTTCCGAGCT 
GGGTTCGTCT GCCCCACTCC ACCCTACAAG TCCCTGGCCC GAGAGCAGAT CAACGCTCTG 
ACCTCCTTCC TGGATGCCAG CTTTGTGTAC AGCTCCGAGC CAAGCCTGGC CAGCCGCCTC 
CGCAACCTCA GCAGCCCCCT GGGCCTCATG GCTGTCAACC AGGAGGTCTC AGACCATGGA 
CTACCCTACC TGCCCTATGA CAGCAAGAAG CCAAGCCCCT GTGAGTTCAT CAACACCACT 
GCCCGTGTGC CCTGCTTCCT GGCAGGTGGA ATTGATCCTC TGGTGCGGGG CCTGCTGGCC 
AAGAAATCCA AGCTGATGAA ACAGAATAAA ATGATGACTG GAGAGCTGCG CAACAAGCTT 
TTCCAGCCAA CTCACAGGAT CCATGGCTTT GACCTGGCTG CCATCAACAC ACAGCGTTGC 
CGGGACCATG GGCAACCTGG GTACAATTCC TGGAGAGCCT TCTGTGACCT CTCACAGCCG 
CAGACACTAG AGGAGTTGAA CACAGTGCTG AAGAGCAAGA TGCTGGCCAA GAAGTTACTG 
GGTCTCTACG GGACCCCTGA CAACATCGAC ATCTGGATAG GGGCCATTGC TGAGCCGCTG 
GTGGAAAGGG GTCGGGTGGG GCCTCTCCTG GCCTGCCTCT TGGGCAAGCA GTTCCAGCAG 
ATCCGTGATG GAGACAGGTT CTGGTGGGAA AACCCTGGGG TCTTCACGAA CGAGCAGAAG 
GACTCTCTAC AGAAAATGTC CTTCTCACGC CTTGTCTGTG ACAACACCCG CATCACCAAG 
GTCCCACGGG ACCCATTCTG GGCCAACAGC TACCCCTATG ACTTCGTGGA TTGCTCAGCC 
ATCGACAAGC TGGACCTGTC ACCCTGGGCC TCAGTGAAGA ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011523110.1
CDS	193..1917
Translation	MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN

Target ORF information:

RefSeq Version	XM_011524808.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lactoperoxidase (LPO), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524808.2

ORF Insert Sequence:

ATGAGGGTCC TTCTCCATCT CCCAGCCCTC CTGGCTTCCC TCATCTTGCT TCAGGCTGCA 
GCATCTACCA CAAGAGCGCA GACTACCAGA ACCTCTGCCA TCTCCGATAC TGTGAGTCAG 
GCCAAGGTCC AAGTCAACAA GGCCTTCCTG GACTCCCGAA CCAGGCTGAA GACCGCCATG 
AGCTCTGAGA CTCCCACCAG CCGACAGCTC TCAGAATACC TCAAGCATGC CAAAGGCCGG 
ACGCGCACAG CCATCCGCAA TGGACAGGTG TGGGAGGAGT CTTTAAAGAG ACTGAGGCAG 
AAGGCATCCT TGACCAATGT CACAGATCCC AGCCTGGACT TGACTTCACT GTCTCTGGAG 
GTGGGCTGTG GTGCTCCTGC TCCCGTGGTG AGATGCGACC CGTGCAGCCC TTACCGCACC 
ATTACGGGAG ACTGCAATAA CAGGAGGAAG CCTGCGCTGG GCGCCGCCAA CAGGGCTCTG 
GCGCGCTGGC TGCCCGCGGA GTACGAGGAC GGGCTCTCCC TGCCCTTCGG CTGGACGCCG 
GGGAAGACGC GCAACGGCTT CCCTCTCCCG CTGGCCCGGG AGGTATCTAA CAAGATTGTT 
GGCTATCTGA ATGAGGAGGG TGTTCTGGAC CAAAACAGGT CCCTGCTCTT CATGCAGTGG 
GGTCAGATTG TGGATCATGA CCTGGACTTT GCCCCTGACA CCGAGCTGGG GAGTAGCGAG 
TACTCCAAAG CCCAGTGTGA TGAGTACTGT ATCCAGGGAG ACAACTGCTT CCCCATCATG 
TTCCCACCCA ATGACCCCAA GGCGGGGACT CAAGGGAAAT GCATGCCTTT CTTCCGAGCT 
GGGTTCGTCT GCCCCACTCC ACCCTACAAG TCCCTGGCCC GAGAGCAGAT CAACGCTCTG 
ACCTCCTTCC TGGATGCCAG CTTTGTGTAC AGCTCCGAGC CAAGCCTGGC CAGCCGCCTC 
CGCAACCTCA GCAGCCCCCT GGGCCTCATG GCTGTCAACC AGGAGGTCTC AGACCATGGA 
CTACCCTACC TGCCCTATGA CAGCAAGAAG CCAAGCCCCT GTGAGTTCAT CAACACCACT 
GCCCGTGTGC CCTGCTTCCT GGCAGGTGGA ATTGATCCTC TGGTGCGGGG CCTGCTGGCC 
AAGAAATCCA AGCTGATGAA ACAGAATAAA ATGATGACTG GAGAGCTGCG CAACAAGCTT 
TTCCAGCCAA CTCACAGGAT CCATGGCTTT GACCTGGCTG CCATCAACAC ACAGCGTTGC 
CGGGACCATG GGCAACCTGG GTACAATTCC TGGAGAGCCT TCTGTGACCT CTCACAGCCG 
CAGACACTAG AGGAGTTGAA CACAGTGCTG AAGAGCAAGA TGCTGGCCAA GAAGTTACTG 
GGTCTCTACG GGACCCCTGA CAACATCGAC ATCTGGATAG GGGCCATTGC TGAGCCGCTG 
GTGGAAAGGG GTCGGGTGGG GCCTCTCCTG GCCTGCCTCT TGGGCAAGCA GTTCCAGCAG 
ATCCGTGATG GAGACAGGTT CTGGTGGGAA AACCCTGGGG TCTTCACGAA CGAGCAGAAG 
GACTCTCTAC AGAAAATGTC CTTCTCACGC CTTGTCTGTG ACAACACCCG CATCACCAAG 
GTCCCACGGG ACCCATTCTG GGCCAACAGC TACCCCTATG ACTTCGTGGA TTGCTCAGCC 
ATCGACAAGC TGGACCTGTC ACCCTGGGCC TCAGTGAAGA ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LPO ( XM_011524810.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011523112.1 Homo sapiens lactoperoxidase (LPO), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu58765
Clone ID Related Accession (Same CDS sequence)	XM_011524810.2
Accession Version	XM_011524810.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lactoperoxidase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524810.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATAATT CCTGGCACAT GTTCCCACCC AATGACCCCA AGGCGGGGAC TCAAGGGAAA 
TGCATGCCTT TCTTCCGAGC TGGGTTCGTC TGCCCCACTC CACCCTACAA GTCCCTGGCC 
CGAGAGCAGA TCAACGCTCT GACCTCCTTC CTGGATGCCA GCTTTGTGTA CAGCTCCGAG 
CCAAGCCTGG CCAGCCGCCT CCGCAACCTC AGCAGCCCCC TGGGCCTCAT GGCTGTCAAC 
CAGGAGGTCT CAGACCATGG ACTACCCTAC CTGCCCTATG ACAGCAAGAA GCCAAGCCCC 
TGTGAGTTCA TCAACACCAC TGCCCGTGTG CCCTGCTTCC TGGCAGGAGA TTCTCGAGCC 
TCAGAGCATA TTCTGCTGGC CACATCCCAC ACCCTCTTTC TCCGCGAGCA TAACCGGCTG 
GCCAGAGAAC TAAAGAGACT CAACCCTCAG TGGGATGGAG AGAAGCTCTA CCAGGAAGCC 
CGGAAAATCC TGGGAGCCTT CGTGCAGATT ATCACCTTTA GGGACTACCT ACCCATTTTG 
CTAGGTGACC ACATGCAGAA GTGGATACCC CCATATCAAG GCTACAGTGA ATCTGTGGAT 
CCCAGAATTT CCAATGTCTT CACCTTCGCC TTCCGCTTTG GCCACTTGGA GGTCCCCTCT 
AGTATGTTCC GCCTGGATGA GAATTATCAG CCATGGGGGC CAGAACCAGA ACTCCCCCTC 
CACACCCTCT TCTTCAACAC TTGGAGGATG GTCAAAGATG GTGGAATTGA TCCTCTGGTG 
CGGGGCCTGC TGGCCAAGAA ATCCAAGCTG ATGAAACAGA ATAAAATGAT GACTGGAGAG 
CTGCGCAACA AGCTTTTCCA GCCAACTCAC AGGATCCATG GCTTTGACCT GGCTGCCATC 
AACACACAGC GTTGCCGGGA CCATGGGCAA CCTGGGTACA ATTCCTGGAG AGCCTTCTGT 
GACCTCTCAC AGCCGCAGAC ACTAGAGGAG TTGAACACAG TGCTGAAGAG CAAGATGCTG 
GCCAAGAAGT TACTGGGTCT CTACGGGACC CCTGACAACA TCGACATCTG GATAGGGGCC 
ATTGCTGAGC CGCTGGTGGA AAGGGGTCGG GTGGGGCCTC TCCTGGCCTG CCTCTTGGGC 
AAGCAGTTCC AGCAGATCCG TGATGGAGAC AGGTTCTGGT GGGAAAACCC TGGGGTCTTC 
ACGAACGAGC AGAAGGACTC TCTACAGAAA ATGTCCTTCT CACGCCTTGT CTGTGACAAC 
ACCCGCATCA CCAAGGTCCC ACGGGACCCA TTCTGGGCCA ACAGCTACCC CTATGACTTC 
GTGGATTGCT CAGCCATCGA CAAGCTGGAC CTGTCACCCT GGGCCTCAGT GAAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011523112.1
CDS	551..1930
Translation	MHNSWHMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN

Target ORF information:

RefSeq Version	XM_011524810.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lactoperoxidase (LPO), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524810.2

ORF Insert Sequence:

ATGCATAATT CCTGGCACAT GTTCCCACCC AATGACCCCA AGGCGGGGAC TCAAGGGAAA 
TGCATGCCTT TCTTCCGAGC TGGGTTCGTC TGCCCCACTC CACCCTACAA GTCCCTGGCC 
CGAGAGCAGA TCAACGCTCT GACCTCCTTC CTGGATGCCA GCTTTGTGTA CAGCTCCGAG 
CCAAGCCTGG CCAGCCGCCT CCGCAACCTC AGCAGCCCCC TGGGCCTCAT GGCTGTCAAC 
CAGGAGGTCT CAGACCATGG ACTACCCTAC CTGCCCTATG ACAGCAAGAA GCCAAGCCCC 
TGTGAGTTCA TCAACACCAC TGCCCGTGTG CCCTGCTTCC TGGCAGGAGA TTCTCGAGCC 
TCAGAGCATA TTCTGCTGGC CACATCCCAC ACCCTCTTTC TCCGCGAGCA TAACCGGCTG 
GCCAGAGAAC TAAAGAGACT CAACCCTCAG TGGGATGGAG AGAAGCTCTA CCAGGAAGCC 
CGGAAAATCC TGGGAGCCTT CGTGCAGATT ATCACCTTTA GGGACTACCT ACCCATTTTG 
CTAGGTGACC ACATGCAGAA GTGGATACCC CCATATCAAG GCTACAGTGA ATCTGTGGAT 
CCCAGAATTT CCAATGTCTT CACCTTCGCC TTCCGCTTTG GCCACTTGGA GGTCCCCTCT 
AGTATGTTCC GCCTGGATGA GAATTATCAG CCATGGGGGC CAGAACCAGA ACTCCCCCTC 
CACACCCTCT TCTTCAACAC TTGGAGGATG GTCAAAGATG GTGGAATTGA TCCTCTGGTG 
CGGGGCCTGC TGGCCAAGAA ATCCAAGCTG ATGAAACAGA ATAAAATGAT GACTGGAGAG 
CTGCGCAACA AGCTTTTCCA GCCAACTCAC AGGATCCATG GCTTTGACCT GGCTGCCATC 
AACACACAGC GTTGCCGGGA CCATGGGCAA CCTGGGTACA ATTCCTGGAG AGCCTTCTGT 
GACCTCTCAC AGCCGCAGAC ACTAGAGGAG TTGAACACAG TGCTGAAGAG CAAGATGCTG 
GCCAAGAAGT TACTGGGTCT CTACGGGACC CCTGACAACA TCGACATCTG GATAGGGGCC 
ATTGCTGAGC CGCTGGTGGA AAGGGGTCGG GTGGGGCCTC TCCTGGCCTG CCTCTTGGGC 
AAGCAGTTCC AGCAGATCCG TGATGGAGAC AGGTTCTGGT GGGAAAACCC TGGGGTCTTC 
ACGAACGAGC AGAAGGACTC TCTACAGAAA ATGTCCTTCT CACGCCTTGT CTGTGACAAC 
ACCCGCATCA CCAAGGTCCC ACGGGACCCA TTCTGGGCCA ACAGCTACCC CTATGACTTC 
GTGGATTGCT CAGCCATCGA CAAGCTGGAC CTGTCACCCT GGGCCTCAGT GAAGAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Design of anti-thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2-mercaptoimidazole at 2.30 ? resolution.
Proteins85(10)1882-1890(2017 Oct)
Sirohi HV,Singh PK,Iqbal N,Sharma P,Singh AK,Kaur P,Sharma S,Singh TP

The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H. pylori.
Digestive diseases and sciences61(8)2328-37(2016 08)
Li H,Zhou Y,Zheng Y,Guo H,Gao L,Chen P,Feng D,Wu L,Yang M,Qi Y,Guo H,Chang Y,Chu FF,Gao Q

Uric acid and thiocyanate as competing substrates of lactoperoxidase.
The Journal of biological chemistry289(32)21937-49(2014 Aug)
Seidel A,Parker H,Turner R,Dickerhof N,Khalilova IS,Wilbanks SM,Kettle AJ,Jameson GN

The assessment of sIgA, histatin-5, and lactoperoxidase levels in saliva of adolescents with dental caries.
Medical science monitor : international medical journal of experimental and clinical research201095-100(2014 Jun)
Gornowicz A,Tokajuk G,Bielawska A,Maciorkowska E,Jab?o?ski R,W?jcicka A,Bielawski K

The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17.
Cytogenetics and cell genetics88(3-4)246-8(2000)
Sakamaki K,Kanda N,Ueda T,Aikawa E,Nagata S

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LPO cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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