LOXL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LOXL2
Entrez Gene ID	4017
Full Name	lysyl oxidase like 2
Synonyms	LOR,LOR2,WS9-14
General protein information	Preferred Names lysyl oxidase like 2 Names lysyl oxidase homolog 2 lysyl oxidase related 2 lysyl oxidase-like 2 delta e13 lysyl oxidase-like 2 protein lysyl oxidase-like protein 2 lysyl oxidase-related protein 2 lysyl oxidase-related protein WS9-14
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p21.3
Summary	This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008].
Disorder MIM:	606663

mRNA and Protein(s)

mRNA	Protein	Name
NM_002318.3	NP_002309.1	lysyl oxidase homolog 2 precursor
NM_002318.2	NP_002309.1	lysyl oxidase homolog 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LOXL2	NP_002309.1
Rattus norvegicus (Norway rat)	Loxl2	NP_001099517.2
	LOXL2	XP_001105440.2
Gallus gallus (chicken)	LOXL2	XP_003642594.1
Xenopus tropicalis (tropical clawed frog)	loxl2	NP_001135520.1
Mus musculus (house mouse)	Loxl2	NP_201582.2
Danio rerio (zebrafish)	loxl2b	NP_001074095.1
Drosophila melanogaster (fruit fly)	lox2	NP_523806.2
Canis lupus familiaris (dog)	LOXL2	XP_543244.3
Bos taurus (cattle)	LOXL2	NP_001092523.1
Anopheles gambiae (African malaria mosquito)	SCRAL1	XP_312996.1

Gene Ontology

The following LOXL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LOXL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16599	NM_002318.3 Latest version!	Homo sapiens lysyl oxidase like 2 (LOXL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
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OHu16599	NM_002318.2	Homo sapiens lysyl oxidase like 2 (LOXL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LOXL2 ( NM_002318.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002309.1 Homo sapiens lysyl oxidase like 2 (LOXL2), mRNA.

Price & Availability↑

CloneID	OHu16599
Clone ID Related Accession (Same CDS sequence)	NM_002318.3 , NM_002318.2
Accession Version	NM_002318.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2325bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	lysyl oxidase homolog 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC104561.3, U89942.1, BC020481.1 and AC090197.23. On May 17, 2019 this sequence version replaced NM_002318.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.118831.1, AK222477.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000389131.8/ ENSP00000373783.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGC CTCTGTGCTC CCACCTCTGC AGCTGCCTGG CTATGCTGGC CCTCCTGTCC 
CCCCTGAGCC TGGCACAGTA TGACAGCTGG CCCCATTACC CCGAGTACTT CCAGCAACCG 
GCTCCTGAGT ATCACCAGCC CCAGGCCCCC GCCAACGTGG CCAAGATTCA GCTGCGCCTG 
GCTGGGCAGA AGAGGAAGCA CAGCGAGGGC CGGGTGGAGG TGTACTATGA TGGCCAGTGG 
GGCACCGTGT GCGATGACGA CTTCTCCATC CACGCTGCCC ACGTCGTCTG CCGGGAGCTG 
GGCTACGTGG AGGCCAAGTC CTGGACTGCC AGCTCCTCCT ACGGCAAGGG AGAAGGGCCC 
ATCTGGTTAG ACAATCTCCA CTGTACTGGC AACGAGGCGA CCCTTGCAGC ATGCACCTCC 
AATGGCTGGG GCGTCACTGA CTGCAAGCAC ACGGAGGATG TCGGTGTGGT GTGCAGCGAC 
AAAAGGATTC CTGGGTTCAA ATTTGACAAT TCGTTGATCA ACCAGATAGA GAACCTGAAT 
ATCCAGGTGG AGGACATTCG GATTCGAGCC ATCCTCTCAA CCTACCGCAA GCGCACCCCA 
GTGATGGAGG GCTACGTGGA GGTGAAGGAG GGCAAGACCT GGAAGCAGAT CTGTGACAAG 
CACTGGACGG CCAAGAATTC CCGCGTGGTC TGCGGCATGT TTGGCTTCCC TGGGGAGAGG 
ACATACAATA CCAAAGTGTA CAAAATGTTT GCCTCACGGA GGAAGCAGCG CTACTGGCCA 
TTCTCCATGG ACTGCACCGG CACAGAGGCC CACATCTCCA GCTGCAAGCT GGGCCCCCAG 
GTGTCACTGG ACCCCATGAA GAATGTCACC TGCGAGAATG GGCTACCGGC CGTGGTGAGT 
TGTGTGCCTG GGCAGGTCTT CAGCCCTGAC GGACCCTCAA GATTCCGGAA AGCGTACAAG 
CCAGAGCAAC CCCTGGTGCG ACTGAGAGGC GGTGCCTACA TCGGGGAGGG CCGCGTGGAG 
GTGCTCAAAA ATGGAGAATG GGGGACCGTC TGCGACGACA AGTGGGACCT GGTGTCGGCC 
AGTGTGGTCT GCAGAGAGCT GGGCTTTGGG AGTGCCAAAG AGGCAGTCAC TGGCTCCCGA 
CTGGGGCAAG GGATCGGACC CATCCACCTC AACGAGATCC AGTGCACAGG CAATGAGAAG 
TCCATTATAG ACTGCAAGTT CAATGCCGAG TCTCAGGGCT GCAACCACGA GGAGGATGCT 
GGTGTGAGAT GCAACACCCC TGCCATGGGC TTGCAGAAGA AGCTGCGCCT GAACGGCGGC 
CGCAATCCCT ACGAGGGCCG AGTGGAGGTG CTGGTGGAGA GAAACGGGTC CCTTGTGTGG 
GGGATGGTGT GTGGCCAAAA CTGGGGCATC GTGGAGGCCA TGGTGGTCTG CCGCCAGCTG 
GGCCTGGGAT TCGCCAGCAA CGCCTTCCAG GAGACCTGGT ATTGGCACGG AGATGTCAAC 
AGCAACAAAG TGGTCATGAG TGGAGTGAAG TGCTCGGGAA CGGAGCTGTC CCTGGCGCAC 
TGCCGCCACG ACGGGGAGGA CGTGGCCTGC CCCCAGGGCG GAGTGCAGTA CGGGGCCGGA 
GTTGCCTGCT CAGAAACCGC CCCTGACCTG GTCCTCAATG CGGAGATGGT GCAGCAGACC 
ACCTACCTGG AGGACCGGCC CATGTTCATG CTGCAGTGTG CCATGGAGGA GAACTGCCTC 
TCGGCCTCAG CCGCGCAGAC CGACCCCACC ACGGGCTACC GCCGGCTCCT GCGCTTCTCC 
TCCCAGATCC ACAACAATGG CCAGTCCGAC TTCCGGCCCA AGAACGGCCG CCACGCGTGG 
ATCTGGCACG ACTGTCACAG GCACTACCAC AGCATGGAGG TGTTCACCCA CTATGACCTG 
CTGAACCTCA ATGGCACCAA GGTGGCAGAG GGCCACAAGG CCAGCTTCTG CTTGGAGGAC 
ACAGAATGTG AAGGAGACAT CCAGAAGAAT TACGAGTGTG CCAACTTCGG CGATCAGGGC 
ATCACCATGG GCTGCTGGGA CATGTACCGC CATGACATCG ACTGCCAGTG GGTTGACATC 
ACTGACGTGC CCCCTGGAGA CTACCTGTTC CAGGTTGTTA TTAACCCCAA CTTCGAGGTT 
GCAGAATCCG ATTACTCCAA CAACATCATG AAATGCAGGA GCCGCTATGA CGGCCACCGC 
ATCTGGATGT ACAACTGCCA CATAGGTGGT TCCTTCAGCG AAGAGACGGA AAAAAAGTTT 
GAGCACTTCA GCGGGCTCTT AAACAACCAG CTGTCCCCGC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002309.1
CDS	251..2575
Translation	MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ

Target ORF information:

RefSeq Version	NM_002318.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lysyl oxidase like 2 (LOXL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002318.3

ORF Insert Sequence:

ATGGAGAGGC CTCTGTGCTC CCACCTCTGC AGCTGCCTGG CTATGCTGGC CCTCCTGTCC 
CCCCTGAGCC TGGCACAGTA TGACAGCTGG CCCCATTACC CCGAGTACTT CCAGCAACCG 
GCTCCTGAGT ATCACCAGCC CCAGGCCCCC GCCAACGTGG CCAAGATTCA GCTGCGCCTG 
GCTGGGCAGA AGAGGAAGCA CAGCGAGGGC CGGGTGGAGG TGTACTATGA TGGCCAGTGG 
GGCACCGTGT GCGATGACGA CTTCTCCATC CACGCTGCCC ACGTCGTCTG CCGGGAGCTG 
GGCTACGTGG AGGCCAAGTC CTGGACTGCC AGCTCCTCCT ACGGCAAGGG AGAAGGGCCC 
ATCTGGTTAG ACAATCTCCA CTGTACTGGC AACGAGGCGA CCCTTGCAGC ATGCACCTCC 
AATGGCTGGG GCGTCACTGA CTGCAAGCAC ACGGAGGATG TCGGTGTGGT GTGCAGCGAC 
AAAAGGATTC CTGGGTTCAA ATTTGACAAT TCGTTGATCA ACCAGATAGA GAACCTGAAT 
ATCCAGGTGG AGGACATTCG GATTCGAGCC ATCCTCTCAA CCTACCGCAA GCGCACCCCA 
GTGATGGAGG GCTACGTGGA GGTGAAGGAG GGCAAGACCT GGAAGCAGAT CTGTGACAAG 
CACTGGACGG CCAAGAATTC CCGCGTGGTC TGCGGCATGT TTGGCTTCCC TGGGGAGAGG 
ACATACAATA CCAAAGTGTA CAAAATGTTT GCCTCACGGA GGAAGCAGCG CTACTGGCCA 
TTCTCCATGG ACTGCACCGG CACAGAGGCC CACATCTCCA GCTGCAAGCT GGGCCCCCAG 
GTGTCACTGG ACCCCATGAA GAATGTCACC TGCGAGAATG GGCTACCGGC CGTGGTGAGT 
TGTGTGCCTG GGCAGGTCTT CAGCCCTGAC GGACCCTCAA GATTCCGGAA AGCGTACAAG 
CCAGAGCAAC CCCTGGTGCG ACTGAGAGGC GGTGCCTACA TCGGGGAGGG CCGCGTGGAG 
GTGCTCAAAA ATGGAGAATG GGGGACCGTC TGCGACGACA AGTGGGACCT GGTGTCGGCC 
AGTGTGGTCT GCAGAGAGCT GGGCTTTGGG AGTGCCAAAG AGGCAGTCAC TGGCTCCCGA 
CTGGGGCAAG GGATCGGACC CATCCACCTC AACGAGATCC AGTGCACAGG CAATGAGAAG 
TCCATTATAG ACTGCAAGTT CAATGCCGAG TCTCAGGGCT GCAACCACGA GGAGGATGCT 
GGTGTGAGAT GCAACACCCC TGCCATGGGC TTGCAGAAGA AGCTGCGCCT GAACGGCGGC 
CGCAATCCCT ACGAGGGCCG AGTGGAGGTG CTGGTGGAGA GAAACGGGTC CCTTGTGTGG 
GGGATGGTGT GTGGCCAAAA CTGGGGCATC GTGGAGGCCA TGGTGGTCTG CCGCCAGCTG 
GGCCTGGGAT TCGCCAGCAA CGCCTTCCAG GAGACCTGGT ATTGGCACGG AGATGTCAAC 
AGCAACAAAG TGGTCATGAG TGGAGTGAAG TGCTCGGGAA CGGAGCTGTC CCTGGCGCAC 
TGCCGCCACG ACGGGGAGGA CGTGGCCTGC CCCCAGGGCG GAGTGCAGTA CGGGGCCGGA 
GTTGCCTGCT CAGAAACCGC CCCTGACCTG GTCCTCAATG CGGAGATGGT GCAGCAGACC 
ACCTACCTGG AGGACCGGCC CATGTTCATG CTGCAGTGTG CCATGGAGGA GAACTGCCTC 
TCGGCCTCAG CCGCGCAGAC CGACCCCACC ACGGGCTACC GCCGGCTCCT GCGCTTCTCC 
TCCCAGATCC ACAACAATGG CCAGTCCGAC TTCCGGCCCA AGAACGGCCG CCACGCGTGG 
ATCTGGCACG ACTGTCACAG GCACTACCAC AGCATGGAGG TGTTCACCCA CTATGACCTG 
CTGAACCTCA ATGGCACCAA GGTGGCAGAG GGCCACAAGG CCAGCTTCTG CTTGGAGGAC 
ACAGAATGTG AAGGAGACAT CCAGAAGAAT TACGAGTGTG CCAACTTCGG CGATCAGGGC 
ATCACCATGG GCTGCTGGGA CATGTACCGC CATGACATCG ACTGCCAGTG GGTTGACATC 
ACTGACGTGC CCCCTGGAGA CTACCTGTTC CAGGTTGTTA TTAACCCCAA CTTCGAGGTT 
GCAGAATCCG ATTACTCCAA CAACATCATG AAATGCAGGA GCCGCTATGA CGGCCACCGC 
ATCTGGATGT ACAACTGCCA CATAGGTGGT TCCTTCAGCG AAGAGACGGA AAAAAAGTTT 
GAGCACTTCA GCGGGCTCTT AAACAACCAG CTGTCCCCGC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LOXL2 ( NM_002318.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002309.1 Homo sapiens lysyl oxidase like 2 (LOXL2), mRNA.

Price & Availability↑

CloneID	OHu16599
Clone ID Related Accession (Same CDS sequence)	NM_002318.3 , NM_002318.2
Accession Version	NM_002318.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2325bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-09
Organism	Homo sapiens(human)
Product	lysyl oxidase homolog 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC104561.3, U89942.1, BC020481.1 and AC090197.23. On Jun 15, 2005 this sequence version replaced NM_002318.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.3919.1, U89942.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGC CTCTGTGCTC CCACCTCTGC AGCTGCCTGG CTATGCTGGC CCTCCTGTCC 
CCCCTGAGCC TGGCACAGTA TGACAGCTGG CCCCATTACC CCGAGTACTT CCAGCAACCG 
GCTCCTGAGT ATCACCAGCC CCAGGCCCCC GCCAACGTGG CCAAGATTCA GCTGCGCCTG 
GCTGGGCAGA AGAGGAAGCA CAGCGAGGGC CGGGTGGAGG TGTACTATGA TGGCCAGTGG 
GGCACCGTGT GCGATGACGA CTTCTCCATC CACGCTGCCC ACGTCGTCTG CCGGGAGCTG 
GGCTACGTGG AGGCCAAGTC CTGGACTGCC AGCTCCTCCT ACGGCAAGGG AGAAGGGCCC 
ATCTGGTTAG ACAATCTCCA CTGTACTGGC AACGAGGCGA CCCTTGCAGC ATGCACCTCC 
AATGGCTGGG GCGTCACTGA CTGCAAGCAC ACGGAGGATG TCGGTGTGGT GTGCAGCGAC 
AAAAGGATTC CTGGGTTCAA ATTTGACAAT TCGTTGATCA ACCAGATAGA GAACCTGAAT 
ATCCAGGTGG AGGACATTCG GATTCGAGCC ATCCTCTCAA CCTACCGCAA GCGCACCCCA 
GTGATGGAGG GCTACGTGGA GGTGAAGGAG GGCAAGACCT GGAAGCAGAT CTGTGACAAG 
CACTGGACGG CCAAGAATTC CCGCGTGGTC TGCGGCATGT TTGGCTTCCC TGGGGAGAGG 
ACATACAATA CCAAAGTGTA CAAAATGTTT GCCTCACGGA GGAAGCAGCG CTACTGGCCA 
TTCTCCATGG ACTGCACCGG CACAGAGGCC CACATCTCCA GCTGCAAGCT GGGCCCCCAG 
GTGTCACTGG ACCCCATGAA GAATGTCACC TGCGAGAATG GGCTACCGGC CGTGGTGAGT 
TGTGTGCCTG GGCAGGTCTT CAGCCCTGAC GGACCCTCAA GATTCCGGAA AGCGTACAAG 
CCAGAGCAAC CCCTGGTGCG ACTGAGAGGC GGTGCCTACA TCGGGGAGGG CCGCGTGGAG 
GTGCTCAAAA ATGGAGAATG GGGGACCGTC TGCGACGACA AGTGGGACCT GGTGTCGGCC 
AGTGTGGTCT GCAGAGAGCT GGGCTTTGGG AGTGCCAAAG AGGCAGTCAC TGGCTCCCGA 
CTGGGGCAAG GGATCGGACC CATCCACCTC AACGAGATCC AGTGCACAGG CAATGAGAAG 
TCCATTATAG ACTGCAAGTT CAATGCCGAG TCTCAGGGCT GCAACCACGA GGAGGATGCT 
GGTGTGAGAT GCAACACCCC TGCCATGGGC TTGCAGAAGA AGCTGCGCCT GAACGGCGGC 
CGCAATCCCT ACGAGGGCCG AGTGGAGGTG CTGGTGGAGA GAAACGGGTC CCTTGTGTGG 
GGGATGGTGT GTGGCCAAAA CTGGGGCATC GTGGAGGCCA TGGTGGTCTG CCGCCAGCTG 
GGCCTGGGAT TCGCCAGCAA CGCCTTCCAG GAGACCTGGT ATTGGCACGG AGATGTCAAC 
AGCAACAAAG TGGTCATGAG TGGAGTGAAG TGCTCGGGAA CGGAGCTGTC CCTGGCGCAC 
TGCCGCCACG ACGGGGAGGA CGTGGCCTGC CCCCAGGGCG GAGTGCAGTA CGGGGCCGGA 
GTTGCCTGCT CAGAAACCGC CCCTGACCTG GTCCTCAATG CGGAGATGGT GCAGCAGACC 
ACCTACCTGG AGGACCGGCC CATGTTCATG CTGCAGTGTG CCATGGAGGA GAACTGCCTC 
TCGGCCTCAG CCGCGCAGAC CGACCCCACC ACGGGCTACC GCCGGCTCCT GCGCTTCTCC 
TCCCAGATCC ACAACAATGG CCAGTCCGAC TTCCGGCCCA AGAACGGCCG CCACGCGTGG 
ATCTGGCACG ACTGTCACAG GCACTACCAC AGCATGGAGG TGTTCACCCA CTATGACCTG 
CTGAACCTCA ATGGCACCAA GGTGGCAGAG GGCCACAAGG CCAGCTTCTG CTTGGAGGAC 
ACAGAATGTG AAGGAGACAT CCAGAAGAAT TACGAGTGTG CCAACTTCGG CGATCAGGGC 
ATCACCATGG GCTGCTGGGA CATGTACCGC CATGACATCG ACTGCCAGTG GGTTGACATC 
ACTGACGTGC CCCCTGGAGA CTACCTGTTC CAGGTTGTTA TTAACCCCAA CTTCGAGGTT 
GCAGAATCCG ATTACTCCAA CAACATCATG AAATGCAGGA GCCGCTATGA CGGCCACCGC 
ATCTGGATGT ACAACTGCCA CATAGGTGGT TCCTTCAGCG AAGAGACGGA AAAAAAGTTT 
GAGCACTTCA GCGGGCTCTT AAACAACCAG CTGTCCCCGC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002309.1
CDS	340..2664
Translation	MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ

Target ORF information:

RefSeq Version	NM_002318.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysyl oxidase like 2 (LOXL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002318.2

ORF Insert Sequence:

ATGGAGAGGC CTCTGTGCTC CCACCTCTGC AGCTGCCTGG CTATGCTGGC CCTCCTGTCC 
CCCCTGAGCC TGGCACAGTA TGACAGCTGG CCCCATTACC CCGAGTACTT CCAGCAACCG 
GCTCCTGAGT ATCACCAGCC CCAGGCCCCC GCCAACGTGG CCAAGATTCA GCTGCGCCTG 
GCTGGGCAGA AGAGGAAGCA CAGCGAGGGC CGGGTGGAGG TGTACTATGA TGGCCAGTGG 
GGCACCGTGT GCGATGACGA CTTCTCCATC CACGCTGCCC ACGTCGTCTG CCGGGAGCTG 
GGCTACGTGG AGGCCAAGTC CTGGACTGCC AGCTCCTCCT ACGGCAAGGG AGAAGGGCCC 
ATCTGGTTAG ACAATCTCCA CTGTACTGGC AACGAGGCGA CCCTTGCAGC ATGCACCTCC 
AATGGCTGGG GCGTCACTGA CTGCAAGCAC ACGGAGGATG TCGGTGTGGT GTGCAGCGAC 
AAAAGGATTC CTGGGTTCAA ATTTGACAAT TCGTTGATCA ACCAGATAGA GAACCTGAAT 
ATCCAGGTGG AGGACATTCG GATTCGAGCC ATCCTCTCAA CCTACCGCAA GCGCACCCCA 
GTGATGGAGG GCTACGTGGA GGTGAAGGAG GGCAAGACCT GGAAGCAGAT CTGTGACAAG 
CACTGGACGG CCAAGAATTC CCGCGTGGTC TGCGGCATGT TTGGCTTCCC TGGGGAGAGG 
ACATACAATA CCAAAGTGTA CAAAATGTTT GCCTCACGGA GGAAGCAGCG CTACTGGCCA 
TTCTCCATGG ACTGCACCGG CACAGAGGCC CACATCTCCA GCTGCAAGCT GGGCCCCCAG 
GTGTCACTGG ACCCCATGAA GAATGTCACC TGCGAGAATG GGCTACCGGC CGTGGTGAGT 
TGTGTGCCTG GGCAGGTCTT CAGCCCTGAC GGACCCTCAA GATTCCGGAA AGCGTACAAG 
CCAGAGCAAC CCCTGGTGCG ACTGAGAGGC GGTGCCTACA TCGGGGAGGG CCGCGTGGAG 
GTGCTCAAAA ATGGAGAATG GGGGACCGTC TGCGACGACA AGTGGGACCT GGTGTCGGCC 
AGTGTGGTCT GCAGAGAGCT GGGCTTTGGG AGTGCCAAAG AGGCAGTCAC TGGCTCCCGA 
CTGGGGCAAG GGATCGGACC CATCCACCTC AACGAGATCC AGTGCACAGG CAATGAGAAG 
TCCATTATAG ACTGCAAGTT CAATGCCGAG TCTCAGGGCT GCAACCACGA GGAGGATGCT 
GGTGTGAGAT GCAACACCCC TGCCATGGGC TTGCAGAAGA AGCTGCGCCT GAACGGCGGC 
CGCAATCCCT ACGAGGGCCG AGTGGAGGTG CTGGTGGAGA GAAACGGGTC CCTTGTGTGG 
GGGATGGTGT GTGGCCAAAA CTGGGGCATC GTGGAGGCCA TGGTGGTCTG CCGCCAGCTG 
GGCCTGGGAT TCGCCAGCAA CGCCTTCCAG GAGACCTGGT ATTGGCACGG AGATGTCAAC 
AGCAACAAAG TGGTCATGAG TGGAGTGAAG TGCTCGGGAA CGGAGCTGTC CCTGGCGCAC 
TGCCGCCACG ACGGGGAGGA CGTGGCCTGC CCCCAGGGCG GAGTGCAGTA CGGGGCCGGA 
GTTGCCTGCT CAGAAACCGC CCCTGACCTG GTCCTCAATG CGGAGATGGT GCAGCAGACC 
ACCTACCTGG AGGACCGGCC CATGTTCATG CTGCAGTGTG CCATGGAGGA GAACTGCCTC 
TCGGCCTCAG CCGCGCAGAC CGACCCCACC ACGGGCTACC GCCGGCTCCT GCGCTTCTCC 
TCCCAGATCC ACAACAATGG CCAGTCCGAC TTCCGGCCCA AGAACGGCCG CCACGCGTGG 
ATCTGGCACG ACTGTCACAG GCACTACCAC AGCATGGAGG TGTTCACCCA CTATGACCTG 
CTGAACCTCA ATGGCACCAA GGTGGCAGAG GGCCACAAGG CCAGCTTCTG CTTGGAGGAC 
ACAGAATGTG AAGGAGACAT CCAGAAGAAT TACGAGTGTG CCAACTTCGG CGATCAGGGC 
ATCACCATGG GCTGCTGGGA CATGTACCGC CATGACATCG ACTGCCAGTG GGTTGACATC 
ACTGACGTGC CCCCTGGAGA CTACCTGTTC CAGGTTGTTA TTAACCCCAA CTTCGAGGTT 
GCAGAATCCG ATTACTCCAA CAACATCATG AAATGCAGGA GCCGCTATGA CGGCCACCGC 
ATCTGGATGT ACAACTGCCA CATAGGTGGT TCCTTCAGCG AAGAGACGGA AAAAAAGTTT 
GAGCACTTCA GCGGGCTCTT AAACAACCAG CTGTCCCCGC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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LOXL2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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