LOXL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LOXL1
Entrez Gene ID	4016
Full Name	lysyl oxidase like 1
Synonyms	LOL,LOXL
General protein information	Preferred Names lysyl oxidase like 1 Names lysyl oxidase homolog 1 lysyl oxidase-like protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q24.1
Summary	This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016].
Disorder MIM:	153456
Disorder Html:	{Exfoliation syndrome, susceptibility to}, 177650 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005576.4	NP_005567.2	lysyl oxidase homolog 1 preproprotein
XM_011521555.1	XP_011519857.1	lysyl oxidase homolog 1 isoform X1
NM_005576.3	NP_005567.2	lysyl oxidase homolog 1 preproprotein
XM_011521555.2	XP_011519857.1	lysyl oxidase homolog 1 isoform X1
NM_005576.2	NP_005567.2	lysyl oxidase homolog 1 preproprotein
XM_017022179.1	XP_016877668.1	lysyl oxidase homolog 1 isoform X2

Pathways from BioSystems

Homologies

	LOXL1	XP_001094837.1
Rattus norvegicus (Norway rat)	Loxl1	NP_001012125.1
Xenopus tropicalis (tropical clawed frog)	loxl1	NP_001096301.1
Pan troglodytes (chimpanzee)	LOXL1	XP_003314806.2
Mus musculus (house mouse)	Loxl1	NP_034859.2
Danio rerio (zebrafish)	loxl1	NP_001036790.1
Homo sapiens (human)	LOXL1	NP_005567.2
Bos taurus (cattle)	LOXL1	NP_776808.1
Gallus gallus (chicken)	LOXL1	XP_424060.4

Gene Ontology
Bibliography

Related articles in PubMed

Posttranscriptional Regulation of LOXL1 Expression Via Alternative Splicing and Nonsense-Mediated mRNA Decay as an Adaptive Stress Response.
Berner D, Zenkel M, Pasutto F, Hoja U, Liravi P, Gusek-Schneider GC, Kruse FE, Sch?del J, Reis A, Schl?tzer-Schrehardt U
Investigative ophthalmology & visual science58(13)5930-5940(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings provide evidence for a functional role of alternative splicing coupled to NMD in the posttranscriptional regulation of LOXL1 gene expression and suggest this mechanism to represent a dynamic mode of adapting LOXL1 expression to PEX-associated environmental and nutritional cues.
Title: Posttranscriptional Regulation of LOXL1 Expression Via Alternative Splicing and Nonsense-Mediated mRNA Decay as an Adaptive Stress Response.

A rare protective allele at LOXL1,Tyr407Phe, was identified. It is found exclusively in the Japanese population. It confers 25-fold resistance to XFS. It segregated with the common rs3825942[A] (p.Asp153) in all but 2 patients examined. In spheroids, this haplotype conferred a significant increase in the strength of cellular adhesion in comparison to 3 haplotypes with the wild-type allele.
Title: Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

LOXL1 transcriptional activity was dramatically reduced when a recombinant DNMT3A was concomitantly overexpressed.
Title: Methylation of LOXL1 Promoter by DNMT3A in Aged Human Skin Fibroblasts.

Findings of this current study indicate a different LOXL1 gene expression pattern compared with a recent study that was also performed in the Turkish population.
Title: Association of Lysyl Oxidase-Like 1 Gene Polymorphism in Turkish Patients With Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.

The LOXL1 SNPs, rs1048661 and rs3825942, are associated with PXF in the South Indian population correlating with lowered LOX activity in the aqueous humor. The increased level of total TGF-beta in the aqueous humor of PXF cases is possibly associated with LOX regulation which needs further investigation.
Title: Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-? Levels and LOXL1 Genotype in Pseudoexfoliation.

The following LOXL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LOXL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19180	NM_005576.4 Latest version!	Homo sapiens lysyl oxidase like 1 (LOXL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu85404	XM_017022179.1 Latest version!	Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu58762	XM_011521555.2 Latest version!	Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu19180	NM_005576.3	Homo sapiens lysyl oxidase like 1 (LOXL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu58762	XM_011521555.1	Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu19180	NM_005576.2	Homo sapiens lysyl oxidase-like 1 (LOXL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LOXL1 ( NM_005576.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005567.2 Homo sapiens lysyl oxidase like 1 (LOXL1), mRNA.

Price & Availability↑

CloneID	OHu19180
Clone ID Related Accession (Same CDS sequence)	NM_005576.4 , NM_005576.3 , NM_005576.2
Accession Version	NM_005576.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	lysyl oxidase homolog 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC068542.1, BC015090.2 and BE205920.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_005576.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015090.2, BC068542.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261921.8/ ENSP00000261921.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGGTCTCCCT GACTTGGTCC CAGACCCCAA CTATGTGCAA 
GCATCCACTT ATGTGCAGAG AGCCCACCTG TACTCCCTGC GCTGTGCTGC GGAGGAGAAG 
TGTCTGGCCA GCACAGCCTA TGCCCCTGAG GCCACCGACT ACGATGTGCG GGTGCTACTG 
CGCTTCCCCC AGCGCGTGAA GAACCAGGGC ACAGCAGACT TCCTCCCCAA CCGGCCACGG 
CACACCTGGG AGTGGCACAG CTGCCACCAG CATTACCACA GCATGGACGA GTTCAGCCAC 
TACGACCTAC TGGATGCAGC CACAGGCAAG AAGGTGGCCG AGGGCCACAA GGCCAGTTTC 
TGCCTGGAGG ACAGCACCTG TGACTTCGGC AACCTCAAGC GCTATGCATG CACCTCTCAT 
ACCCAGGGCC TGAGCCCAGG CTGCTATGAC ACCTACAATG CGGACATCGA CTGCCAGTGG 
ATCGACATAA CCGACGTGCA GCCTGGGAAC TACATCCTCA AGGTGCACGT GAACCCAAAG 
TATATTGTTT TGGAGTCTGA CTTCACCAAC AACGTGGTGA GATGCAACAT TCACTACACA 
GGTCGCTACG TTTCTGCAAC AAACTGCAAA ATTGTCCAAT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005567.2
CDS	323..2047
Translation	MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS

Target ORF information:

RefSeq Version	NM_005576.4
Organism	Homo sapiens(human)
Definition	Homo sapiens lysyl oxidase like 1 (LOXL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005576.4

ORF Insert Sequence:

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGGTCTCCCT GACTTGGTCC CAGACCCCAA CTATGTGCAA 
GCATCCACTT ATGTGCAGAG AGCCCACCTG TACTCCCTGC GCTGTGCTGC GGAGGAGAAG 
TGTCTGGCCA GCACAGCCTA TGCCCCTGAG GCCACCGACT ACGATGTGCG GGTGCTACTG 
CGCTTCCCCC AGCGCGTGAA GAACCAGGGC ACAGCAGACT TCCTCCCCAA CCGGCCACGG 
CACACCTGGG AGTGGCACAG CTGCCACCAG CATTACCACA GCATGGACGA GTTCAGCCAC 
TACGACCTAC TGGATGCAGC CACAGGCAAG AAGGTGGCCG AGGGCCACAA GGCCAGTTTC 
TGCCTGGAGG ACAGCACCTG TGACTTCGGC AACCTCAAGC GCTATGCATG CACCTCTCAT 
ACCCAGGGCC TGAGCCCAGG CTGCTATGAC ACCTACAATG CGGACATCGA CTGCCAGTGG 
ATCGACATAA CCGACGTGCA GCCTGGGAAC TACATCCTCA AGGTGCACGT GAACCCAAAG 
TATATTGTTT TGGAGTCTGA CTTCACCAAC AACGTGGTGA GATGCAACAT TCACTACACA 
GGTCGCTACG TTTCTGCAAC AAACTGCAAA ATTGTCCAAT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LOXL1 ( NM_005576.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005567.2 Homo sapiens lysyl oxidase like 1 (LOXL1), mRNA.

Price & Availability↑

CloneID	OHu19180
Clone ID Related Accession (Same CDS sequence)	NM_005576.4 , NM_005576.3 , NM_005576.2
Accession Version	NM_005576.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	lysyl oxidase homolog 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC068542.1, BC015090.2, BE205920.1 and AI565419.1. This sequence is a reference standard in the RefSeqGene project. On Jan 15, 2016 this sequence version replaced NM_005576.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068542.1, BC015090.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGGTCTCCCT GACTTGGTCC CAGACCCCAA CTATGTGCAA 
GCATCCACTT ATGTGCAGAG AGCCCACCTG TACTCCCTGC GCTGTGCTGC GGAGGAGAAG 
TGTCTGGCCA GCACAGCCTA TGCCCCTGAG GCCACCGACT ACGATGTGCG GGTGCTACTG 
CGCTTCCCCC AGCGCGTGAA GAACCAGGGC ACAGCAGACT TCCTCCCCAA CCGGCCACGG 
CACACCTGGG AGTGGCACAG CTGCCACCAG CATTACCACA GCATGGACGA GTTCAGCCAC 
TACGACCTAC TGGATGCAGC CACAGGCAAG AAGGTGGCCG AGGGCCACAA GGCCAGTTTC 
TGCCTGGAGG ACAGCACCTG TGACTTCGGC AACCTCAAGC GCTATGCATG CACCTCTCAT 
ACCCAGGGCC TGAGCCCAGG CTGCTATGAC ACCTACAATG CGGACATCGA CTGCCAGTGG 
ATCGACATAA CCGACGTGCA GCCTGGGAAC TACATCCTCA AGGTGCACGT GAACCCAAAG 
TATATTGTTT TGGAGTCTGA CTTCACCAAC AACGTGGTGA GATGCAACAT TCACTACACA 
GGTCGCTACG TTTCTGCAAC AAACTGCAAA ATTGTCCAAT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005567.2
CDS	327..2051
Translation	MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS

Target ORF information:

RefSeq Version	NM_005576.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lysyl oxidase like 1 (LOXL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005576.3

ORF Insert Sequence:

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGGTCTCCCT GACTTGGTCC CAGACCCCAA CTATGTGCAA 
GCATCCACTT ATGTGCAGAG AGCCCACCTG TACTCCCTGC GCTGTGCTGC GGAGGAGAAG 
TGTCTGGCCA GCACAGCCTA TGCCCCTGAG GCCACCGACT ACGATGTGCG GGTGCTACTG 
CGCTTCCCCC AGCGCGTGAA GAACCAGGGC ACAGCAGACT TCCTCCCCAA CCGGCCACGG 
CACACCTGGG AGTGGCACAG CTGCCACCAG CATTACCACA GCATGGACGA GTTCAGCCAC 
TACGACCTAC TGGATGCAGC CACAGGCAAG AAGGTGGCCG AGGGCCACAA GGCCAGTTTC 
TGCCTGGAGG ACAGCACCTG TGACTTCGGC AACCTCAAGC GCTATGCATG CACCTCTCAT 
ACCCAGGGCC TGAGCCCAGG CTGCTATGAC ACCTACAATG CGGACATCGA CTGCCAGTGG 
ATCGACATAA CCGACGTGCA GCCTGGGAAC TACATCCTCA AGGTGCACGT GAACCCAAAG 
TATATTGTTT TGGAGTCTGA CTTCACCAAC AACGTGGTGA GATGCAACAT TCACTACACA 
GGTCGCTACG TTTCTGCAAC AAACTGCAAA ATTGTCCAAT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LOXL1 ( NM_005576.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005567.2 Homo sapiens lysyl oxidase-like 1 (LOXL1), mRNA.

Price & Availability↑

CloneID	OHu19180
Clone ID Related Accession (Same CDS sequence)	NM_005576.4 , NM_005576.3 , NM_005576.2
Accession Version	NM_005576.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	lysyl oxidase homolog 1 preproprotein
Comment

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGGTCTCCCT GACTTGGTCC CAGACCCCAA CTATGTGCAA 
GCATCCACTT ATGTGCAGAG AGCCCACCTG TACTCCCTGC GCTGTGCTGC GGAGGAGAAG 
TGTCTGGCCA GCACAGCCTA TGCCCCTGAG GCCACCGACT ACGATGTGCG GGTGCTACTG 
CGCTTCCCCC AGCGCGTGAA GAACCAGGGC ACAGCAGACT TCCTCCCCAA CCGGCCACGG 
CACACCTGGG AGTGGCACAG CTGCCACCAG CATTACCACA GCATGGACGA GTTCAGCCAC 
TACGACCTAC TGGATGCAGC CACAGGCAAG AAGGTGGCCG AGGGCCACAA GGCCAGTTTC 
TGCCTGGAGG ACAGCACCTG TGACTTCGGC AACCTCAAGC GCTATGCATG CACCTCTCAT 
ACCCAGGGCC TGAGCCCAGG CTGCTATGAC ACCTACAATG CGGACATCGA CTGCCAGTGG 
ATCGACATAA CCGACGTGCA GCCTGGGAAC TACATCCTCA AGGTGCACGT GAACCCAAAG 
TATATTGTTT TGGAGTCTGA CTTCACCAAC AACGTGGTGA GATGCAACAT TCACTACACA 
GGTCGCTACG TTTCTGCAAC AAACTGCAAA ATTGTCCAAT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_005567.2

Translation

MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS

Target ORF information:

RefSeq Version	NM_005576.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens lysyl oxidase-like 1 (LOXL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005576.2

ORF Insert Sequence:

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGGTCTCCCT GACTTGGTCC CAGACCCCAA CTATGTGCAA 
GCATCCACTT ATGTGCAGAG AGCCCACCTG TACTCCCTGC GCTGTGCTGC GGAGGAGAAG 
TGTCTGGCCA GCACAGCCTA TGCCCCTGAG GCCACCGACT ACGATGTGCG GGTGCTACTG 
CGCTTCCCCC AGCGCGTGAA GAACCAGGGC ACAGCAGACT TCCTCCCCAA CCGGCCACGG 
CACACCTGGG AGTGGCACAG CTGCCACCAG CATTACCACA GCATGGACGA GTTCAGCCAC 
TACGACCTAC TGGATGCAGC CACAGGCAAG AAGGTGGCCG AGGGCCACAA GGCCAGTTTC 
TGCCTGGAGG ACAGCACCTG TGACTTCGGC AACCTCAAGC GCTATGCATG CACCTCTCAT 
ACCCAGGGCC TGAGCCCAGG CTGCTATGAC ACCTACAATG CGGACATCGA CTGCCAGTGG 
ATCGACATAA CCGACGTGCA GCCTGGGAAC TACATCCTCA AGGTGCACGT GAACCCAAAG 
TATATTGTTT TGGAGTCTGA CTTCACCAAC AACGTGGTGA GATGCAACAT TCACTACACA 
GGTCGCTACG TTTCTGCAAC AAACTGCAAA ATTGTCCAAT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LOXL1 ( XM_017022179.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877668.1 Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X3, mRNA.

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CloneID	OHu85404
Clone ID Related Accession (Same CDS sequence)	XM_017022179.1
Accession Version	XM_017022179.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lysyl oxidase homolog 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAAGC TTTTCCAGGA AGTCTTAGCA GCTCCCACAC CGCAGAGCTC GAGATGTCTC 
CCTGACTTGG TCCCAGACCC CAACTATGTG CAAGCATCCA CTTATGTGCA GAGAGCCCAC 
CTGTACTCCC TGCGCTGTGC TGCGGAGGAG AAGTGTCTGG CCAGCACAGC CTATGCCCCT 
GAGGCCACCG ACTACGATGT GCGGGTGCTA CTGCGCTTCC CCCAGCGCGT GAAGAACCAG 
GGCACAGCAG ACTTCCTCCC CAACCGGCCA CGGCACACCT GGGAGTGGCA CAGCTGCCAC 
CAGCATTACC ACAGCATGGA CGAGTTCAGC CACTACGACC TACTGGATGC AGCCACAGGC 
AAGAAGGTGG CCGAGGGCCA CAAGGCCAGT TTCTGCCTGG AGGACAGCAC CTGTGACTTC 
GGCAACCTCA AGCGCTATGC ATGCACCTCT CATACCCAGG GCCTGAGCCC AGGCTGCTAT 
GACACCTACA ATGCGGACAT CGACTGCCAG TGGATCGACA TAACCGACGT GCAGCCTGGG 
AACTACATCC TCAAGGTGCA CGTGAACCCA AAGTATATTG TTTTGGAGTC TGACTTCACC 
AACAACGTGG TGAGATGCAA CATTCACTAC ACAGGTCGCT ACGTTTCTGC AACAAACTGC 
AAAATTGTCC AATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877668.1
CDS	390..1067
Translation	MSKLFQEVLAAPTPQSSRCLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS

Target ORF information:

RefSeq Version	XM_017022179.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022179.1

ORF Insert Sequence:

ATGTCCAAGC TTTTCCAGGA AGTCTTAGCA GCTCCCACAC CGCAGAGCTC GAGATGTCTC 
CCTGACTTGG TCCCAGACCC CAACTATGTG CAAGCATCCA CTTATGTGCA GAGAGCCCAC 
CTGTACTCCC TGCGCTGTGC TGCGGAGGAG AAGTGTCTGG CCAGCACAGC CTATGCCCCT 
GAGGCCACCG ACTACGATGT GCGGGTGCTA CTGCGCTTCC CCCAGCGCGT GAAGAACCAG 
GGCACAGCAG ACTTCCTCCC CAACCGGCCA CGGCACACCT GGGAGTGGCA CAGCTGCCAC 
CAGCATTACC ACAGCATGGA CGAGTTCAGC CACTACGACC TACTGGATGC AGCCACAGGC 
AAGAAGGTGG CCGAGGGCCA CAAGGCCAGT TTCTGCCTGG AGGACAGCAC CTGTGACTTC 
GGCAACCTCA AGCGCTATGC ATGCACCTCT CATACCCAGG GCCTGAGCCC AGGCTGCTAT 
GACACCTACA ATGCGGACAT CGACTGCCAG TGGATCGACA TAACCGACGT GCAGCCTGGG 
AACTACATCC TCAAGGTGCA CGTGAACCCA AAGTATATTG TTTTGGAGTC TGACTTCACC 
AACAACGTGG TGAGATGCAA CATTCACTAC ACAGGTCGCT ACGTTTCTGC AACAAACTGC 
AAAATTGTCC AATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LOXL1 ( XM_011521555.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519857.1 Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X1, mRNA.

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CloneID	OHu58762
Clone ID Related Accession (Same CDS sequence)	XM_011521555.1 , XM_011521555.2
Accession Version	XM_011521555.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	lysyl oxidase homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGTAACTCCT GCTCAGACTC CTGCATGCCC AGGGAGGAAG 
GTGGAGGGGC AGGAACAGGA CGGACAGGCC CCGGGCTCTG GCACATCCTG GGGAACAAGG 
GACCACAAGG ACGGGGGCAG TCTCCAGACT TCCCCTGGGC GCTTGACCCC AGGCCTTGCA 
GGGGAGAGAG CCAGGGCCTC CCTCAGGTCT TTGTTCATGC TGTTTTCCCT GCCGTGGACA 
CCCTTTCCCG CTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519857.1
CDS	334..1671
Translation	MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRVTPAQTPACPGRKVEGQEQDGQAPGSGTSWGTRDHKDGGSLQTSPGRLTPGLAGERARASLRSLFMLFSLPWTPFPAL

Target ORF information:

RefSeq Version	XM_011521555.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521555.1

ORF Insert Sequence:

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGTAACTCCT GCTCAGACTC CTGCATGCCC AGGGAGGAAG 
GTGGAGGGGC AGGAACAGGA CGGACAGGCC CCGGGCTCTG GCACATCCTG GGGAACAAGG 
GACCACAAGG ACGGGGGCAG TCTCCAGACT TCCCCTGGGC GCTTGACCCC AGGCCTTGCA 
GGGGAGAGAG CCAGGGCCTC CCTCAGGTCT TTGTTCATGC TGTTTTCCCT GCCGTGGACA 
CCCTTTCCCG CTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LOXL1 ( XM_011521555.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519857.1 Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58762
Clone ID Related Accession (Same CDS sequence)	XM_011521555.1 , XM_011521555.2
Accession Version	XM_011521555.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lysyl oxidase homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011521555.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGTAACTCCT GCTCAGACTC CTGCATGCCC AGGGAGGAAG 
GTGGAGGGGC AGGAACAGGA CGGACAGGCC CCGGGCTCTG GCACATCCTG GGGAACAAGG 
GACCACAAGG ACGGGGGCAG TCTCCAGACT TCCCCTGGGC GCTTGACCCC AGGCCTTGCA 
GGGGAGAGAG CCAGGGCCTC CCTCAGGTCT TTGTTCATGC TGTTTTCCCT GCCGTGGACA 
CCCTTTCCCG CTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519857.1
CDS	323..1660
Translation	MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRVTPAQTPACPGRKVEGQEQDGQAPGSGTSWGTRDHKDGGSLQTSPGRLTPGLAGERARASLRSLFMLFSLPWTPFPAL

Target ORF information:

RefSeq Version	XM_011521555.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysyl oxidase like 1 (LOXL1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521555.2

ORF Insert Sequence:

ATGGCTCTGG CCCGAGGCAG CCGGCAGCTG GGGGCCCTGG TGTGGGGCGC CTGCCTGTGC 
GTGCTGGTGC ACGGGCAGCA GGCGCAGCCC GGGCAGGGCT CGGACCCCGC CCGCTGGCGG 
CAGCTGATCC AGTGGGAGAA CAACGGGCAG GTGTACAGCT TGCTCAACTC GGGCTCAGAG 
TACGTGCCGG CCGGACCTCA GCGCTCCGAG AGTAGCTCCC GGGTGCTGCT GGCCGGCGCG 
CCCCAGGCCC AGCAGCGGCG CAGCCACGGG AGCCCCCGGC GTCGGCAGGC GCCGTCCCTG 
CCCCTGCCGG GGCGCGTGGG CTCGGACACC GTGCGCGGCC AGGCGCGGCA CCCATTCGGC 
TTTGGCCAGG TGCCCGACAA CTGGCGCGAG GTGGCCGTCG GGGACAGCAC GGGCATGGCC 
CGGGCCCGCA CCTCCGTCTC CCAGCAACGG CACGGGGGCT CCGCCTCCTC GGTCTCGGCT 
TCGGCCTTCG CCAGCACCTA CCGCCAGCAG CCCTCCTACC CGCAGCAGTT CCCCTACCCG 
CAGGCGCCCT TCGTCAGCCA GTACGAGAAC TACGACCCCG CGTCGCGGAC CTACGACCAG 
GGTTTCGTGT ACTACCGGCC CGCGGGCGGC GGCGTGGGCG CGGGGGCGGC GGCCGTGGCC 
TCGGCGGGGG TCATCTACCC CTACCAGCCC CGGGCGCGCT ACGAGGAGTA CGGCGGCGGC 
GAAGAGCTGC CCGAGTACCC GCCTCAGGGC TTCTACCCGG CCCCCGAGAG GCCCTACGTG 
CCGCCGCCGC CGCCGCCCCC CGACGGCCTG GACCGCCGCT ACTCGCACAG TCTGTACAGC 
GAGGGCACCC CCGGCTTCGA GCAGGCCTAC CCTGACCCCG GTCCCGAGGC GGCGCAGGCC 
CATGGCGGAG ACCCACGCCT GGGCTGGTAC CCGCCCTACG CCAACCCGCC GCCCGAGGCG 
TACGGGCCGC CGCGCGCGCT GGAGCCGCCC TACCTGCCGG TGCGCAGCTC CGACACGCCC 
CCGCCGGGTG GGGAGCGGAA CGGCGCGCAG CAGGGCCGCC TCAGCGTGGG CAGCGTGTAC 
CGGCCCAACC AGAACGGCCG CGTAACTCCT GCTCAGACTC CTGCATGCCC AGGGAGGAAG 
GTGGAGGGGC AGGAACAGGA CGGACAGGCC CCGGGCTCTG GCACATCCTG GGGAACAAGG 
GACCACAAGG ACGGGGGCAG TCTCCAGACT TCCCCTGGGC GCTTGACCCC AGGCCTTGCA 
GGGGAGAGAG CCAGGGCCTC CCTCAGGTCT TTGTTCATGC TGTTTTCCCT GCCGTGGACA 
CCCTTTCCCG CTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Posttranscriptional Regulation of LOXL1 Expression Via Alternative Splicing and Nonsense-Mediated mRNA Decay as an Adaptive Stress Response.
Investigative ophthalmology & visual science58(13)5930-5940(2017 Nov)
Berner D,Zenkel M,Pasutto F,Hoja U,Liravi P,Gusek-Schneider GC,Kruse FE,Sch?del J,Reis A,Schl?tzer-Schrehardt U

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LOXL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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