RGS7BP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RGS7BP
Entrez Gene ID	401190
Full Name	regulator of G protein signaling 7 binding protein
Synonyms	R7BP
General protein information	Preferred Names regulator of G protein signaling 7 binding protein Names regulator of G-protein signaling 7-binding protein R7 family-binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q12.3
Summary	This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between the nucleus and the plasma membrane. The encoded protein could be regulated by reversible palmitoylation, which anchors it to the plasma membrane. Depalmitoylation localizes the protein to the nucleus. Polymorphisms in this gene may be associated with risk of aspirin-exacerbated respiratory disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012].
Disorder MIM:	610890

mRNA and Protein(s)

mRNA	Protein	Name
XM_005248502.3	XP_005248559.1	regulator of G-protein signaling 7-binding protein isoform X1
NM_001271890.1	NP_001258819.1	regulator of G-protein signaling 7-binding protein isoform 2
NM_001029875.2	NP_001025046.1	regulator of G-protein signaling 7-binding protein isoform 1
NM_001029875.3	NP_001025046.1	regulator of G-protein signaling 7-binding protein isoform 1
NM_001271891.1	NP_001258820.1	regulator of G-protein signaling 7-binding protein isoform 3
XM_005248502.4	XP_005248559.1	regulator of G-protein signaling 7-binding protein isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	RGS7BP	NP_001025046.1
Pan troglodytes (chimpanzee)	RGS7BP	XP_518191.2
	RGS7BP	XP_001083526.1
Canis lupus familiaris (dog)	RGS7BP	XP_851928.1
Bos taurus (cattle)	RGS7BP	NP_001070398.1
Danio rerio (zebrafish)	rgs7bpa	NP_001070076.1
Xenopus tropicalis (tropical clawed frog)	rgs7bp	XP_002934243.1
Mus musculus (house mouse)	Rgs7bp	NP_084155.2
Rattus norvegicus (Norway rat)	Rgs7bp	NP_001012347.1
Gallus gallus (chicken)	RGS7BP	XP_001234192.2

Gene Ontology
Bibliography

Related articles in PubMed

Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit G?
Scherer SL, Cain MD, Kanai SM, Kaltenbronn KM, Blumer KJ
The Journal of biological chemistry292(24)9906-9918(2017 06)

Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by G?o and R7-binding Protein.
Tayou J, Wang Q, Jang GF, Pronin AN, Orlandi C, Martemyanov KA, Crabb JW, Slepak VZ
The Journal of biological chemistry291(17)9133-47(2016 Apr)

Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients.
Lee EH, Park BL, Park SM, Lee SH, Park SW, Park JS, Uh ST, Kim MK, Choi IS, Cho SH, Hong CS, Lee JY, Choi BW, Shin HD, Park CS
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology106(4)292-300.e6(2011 Apr)

RGS11 interacts preferentially with R7BP over Galpha(oa)--characterization of Gbeta5-free RGS11.
Saleem Y, Kim KS
Biochemical and biophysical research communications386(1)65-70(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data (including data from studies using transgenic mice) suggest that R7BP-RGS7 heterotrimers interact with Galpha13 to augment signaling pathways in neurons that regulate neurite morphogenesis. (R7BP = RGS7 family binding protein; RGS7 = regulator of G-protein signaling 7 protein; Galpha13 = GTP-binding protein alpha subunit 13)
Title: Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit G?

R7-binding protein had a strong inhibitory effect on homo-oligomerization of RGS7.
Title: Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by G?o and R7-binding Protein.

BL3-ht2 of RGS7BP may be an important genetic variant associated with AERD. The haplotype of block 3 may play a protective role against aspirin hypersensitivity in asthma, perhaps by altering the responsiveness of muscarinic receptors.
Title: Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

the successful purification of functionally intact Gbeta5-free recombinant RGS11 was reported that differentially interact with R7BP and Galpha(oa).
Title: RGS11 interacts preferentially with R7BP over Galpha(oa)--characterization of Gbeta5-free RGS11.

The following RGS7BP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RGS7BP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08179	NM_001029875.3 Latest version!	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08425	NM_001271890.1 Latest version!	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu08673	NM_001271891.1 Latest version!	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu39575	XM_005248502.4 Latest version!	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu08179	NM_001029875.2	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu39575	XM_005248502.3	Homo sapiens regulator of G-protein signaling 7 binding protein (RGS7BP), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RGS7BP ( NM_001029875.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001025046.1 Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08179
Clone ID Related Accession (Same CDS sequence)	NM_001029875.2 , NM_001029875.3
Accession Version	NM_001029875.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 7-binding protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA404068.1, AK296443.1, AC008854.3 and BX640900.1. On Dec 11, 2012 this sequence version replaced NM_001029875.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BX640900.1, SRR1660807.91693.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGAGTTCTG CACCGAATGG GCGCAAAAAG CGCCCCAGCC GGTCCACCCG CTCCTCGATC 
TTCCAGATCA GCAAGCCCCC GCTGCAGAGC GGAGATTGGG AGCGCAGGGG CAGCGGCTCC 
GAGAGCGCCC ACAAAACCCA ACGAGCCCTG GACGACTGCA AGATGCTTGT CCAAGAGTTC 
AACACACAAG TGGCCCTGTA CCGAGAGCTG GTCATTTCTA TTGGGGATGT CTCGGTCAGC 
TGCCCCTCAC TCCGGGCGGA AATGCACAAG ACAAGAACCA AAGGCTGTGA AATGGCCCGT 
CAGGCACACC AAAAATTGGC TGCCATCTCA GGCCCGGAAG ATGGTGAGAT CCATCCAGAA 
ATCTGTCGGC TTTACATCCA GCTGCAGTGC TGCTTAGAAA TGTATACCAC AGAGATGCTA 
AAATCCATAT GTCTGCTGGG GTCTCTTCAG TTTCATCGAA AAGGAAAGGA ACCTGGCGGG 
GGAACCAAGA GTTTGGATTG CAAAATTGAG GAGAGTGCTG AAACACCTGC CCTAGAAGAC 
TCCTCATCAT CCCCCGTAGA TAGTCAGCAA CATTCCTGGC AGGTTTCCAC AGACATTGAG 
AACACTGAAA GAGACATGAG AGAAATGAAA AACCTTTTAA GCAAACTCAG GGAAACTATG 
CCTTTACCAT TGAAAAATCA AGATGACAGC AGCCTTCTGA ATCTAACTCC CTACCCCCTG 
GTGAGAAGAC GGAAGAGAAG GTTCTTTGGG CTGTGTTGTC TCATCTCAAG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001025046.1
CDS	679..1452
Translation	MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS

Target ORF information:

RefSeq Version	NM_001029875.2
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001029875.2

ORF Insert Sequence:

ATGAGTTCTG CACCGAATGG GCGCAAAAAG CGCCCCAGCC GGTCCACCCG CTCCTCGATC 
TTCCAGATCA GCAAGCCCCC GCTGCAGAGC GGAGATTGGG AGCGCAGGGG CAGCGGCTCC 
GAGAGCGCCC ACAAAACCCA ACGAGCCCTG GACGACTGCA AGATGCTTGT CCAAGAGTTC 
AACACACAAG TGGCCCTGTA CCGAGAGCTG GTCATTTCTA TTGGGGATGT CTCGGTCAGC 
TGCCCCTCAC TCCGGGCGGA AATGCACAAG ACAAGAACCA AAGGCTGTGA AATGGCCCGT 
CAGGCACACC AAAAATTGGC TGCCATCTCA GGCCCGGAAG ATGGTGAGAT CCATCCAGAA 
ATCTGTCGGC TTTACATCCA GCTGCAGTGC TGCTTAGAAA TGTATACCAC AGAGATGCTA 
AAATCCATAT GTCTGCTGGG GTCTCTTCAG TTTCATCGAA AAGGAAAGGA ACCTGGCGGG 
GGAACCAAGA GTTTGGATTG CAAAATTGAG GAGAGTGCTG AAACACCTGC CCTAGAAGAC 
TCCTCATCAT CCCCCGTAGA TAGTCAGCAA CATTCCTGGC AGGTTTCCAC AGACATTGAG 
AACACTGAAA GAGACATGAG AGAAATGAAA AACCTTTTAA GCAAACTCAG GGAAACTATG 
CCTTTACCAT TGAAAAATCA AGATGACAGC AGCCTTCTGA ATCTAACTCC CTACCCCCTG 
GTGAGAAGAC GGAAGAGAAG GTTCTTTGGG CTGTGTTGTC TCATCTCAAG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS7BP ( NM_001029875.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001025046.1 Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08179
Clone ID Related Accession (Same CDS sequence)	NM_001029875.2 , NM_001029875.3
Accession Version	NM_001029875.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 7-binding protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA404068.1, AK296443.1, AC008854.3 and BX640900.1. On May 17, 2019 this sequence version replaced NM_001029875.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.263544.1, SRR1660807.186953.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000334025.3/ ENSP00000334851.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGAGTTCTG CACCGAATGG GCGCAAAAAG CGCCCCAGCC GGTCCACCCG CTCCTCGATC 
TTCCAGATCA GCAAGCCCCC GCTGCAGAGC GGAGATTGGG AGCGCAGGGG CAGCGGCTCC 
GAGAGCGCCC ACAAAACCCA ACGAGCCCTG GACGACTGCA AGATGCTTGT CCAAGAGTTC 
AACACACAAG TGGCCCTGTA CCGAGAGCTG GTCATTTCTA TTGGGGATGT CTCGGTCAGC 
TGCCCCTCAC TCCGGGCGGA AATGCACAAG ACAAGAACCA AAGGCTGTGA AATGGCCCGT 
CAGGCACACC AAAAATTGGC TGCCATCTCA GGCCCGGAAG ATGGTGAGAT CCATCCAGAA 
ATCTGTCGGC TTTACATCCA GCTGCAGTGC TGCTTAGAAA TGTATACCAC AGAGATGCTA 
AAATCCATAT GTCTGCTGGG GTCTCTTCAG TTTCATCGAA AAGGAAAGGA ACCTGGCGGG 
GGAACCAAGA GTTTGGATTG CAAAATTGAG GAGAGTGCTG AAACACCTGC CCTAGAAGAC 
TCCTCATCAT CCCCCGTAGA TAGTCAGCAA CATTCCTGGC AGGTTTCCAC AGACATTGAG 
AACACTGAAA GAGACATGAG AGAAATGAAA AACCTTTTAA GCAAACTCAG GGAAACTATG 
CCTTTACCAT TGAAAAATCA AGATGACAGC AGCCTTCTGA ATCTAACTCC CTACCCCCTG 
GTGAGAAGAC GGAAGAGAAG GTTCTTTGGG CTGTGTTGTC TCATCTCAAG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001025046.1
CDS	611..1384
Translation	MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS

Target ORF information:

RefSeq Version	NM_001029875.3
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001029875.3

ORF Insert Sequence:

ATGAGTTCTG CACCGAATGG GCGCAAAAAG CGCCCCAGCC GGTCCACCCG CTCCTCGATC 
TTCCAGATCA GCAAGCCCCC GCTGCAGAGC GGAGATTGGG AGCGCAGGGG CAGCGGCTCC 
GAGAGCGCCC ACAAAACCCA ACGAGCCCTG GACGACTGCA AGATGCTTGT CCAAGAGTTC 
AACACACAAG TGGCCCTGTA CCGAGAGCTG GTCATTTCTA TTGGGGATGT CTCGGTCAGC 
TGCCCCTCAC TCCGGGCGGA AATGCACAAG ACAAGAACCA AAGGCTGTGA AATGGCCCGT 
CAGGCACACC AAAAATTGGC TGCCATCTCA GGCCCGGAAG ATGGTGAGAT CCATCCAGAA 
ATCTGTCGGC TTTACATCCA GCTGCAGTGC TGCTTAGAAA TGTATACCAC AGAGATGCTA 
AAATCCATAT GTCTGCTGGG GTCTCTTCAG TTTCATCGAA AAGGAAAGGA ACCTGGCGGG 
GGAACCAAGA GTTTGGATTG CAAAATTGAG GAGAGTGCTG AAACACCTGC CCTAGAAGAC 
TCCTCATCAT CCCCCGTAGA TAGTCAGCAA CATTCCTGGC AGGTTTCCAC AGACATTGAG 
AACACTGAAA GAGACATGAG AGAAATGAAA AACCTTTTAA GCAAACTCAG GGAAACTATG 
CCTTTACCAT TGAAAAATCA AGATGACAGC AGCCTTCTGA ATCTAACTCC CTACCCCCTG 
GTGAGAAGAC GGAAGAGAAG GTTCTTTGGG CTGTGTTGTC TCATCTCAAG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS7BP ( NM_001271890.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258819.1 Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08425
Clone ID Related Accession (Same CDS sequence)	NM_001271890.1
Accession Version	NM_001271890.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 375bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 7-binding protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA211241.1, AK296494.1, AC008854.3 and BX640900.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks two alternate exons in the 5' coding region and uses a downstream start codon compared to variant 1. It encodes isoform 2 which has a shorter N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.183101.1, SRR1803613.248356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGTATACCA CAGAGATGCT AAAATCCATA TGTCTGCTGG GGTCTCTTCA GTTTCATCGA 
AAAGGAAAGG AACCTGGCGG GGGAACCAAG AGTTTGGATT GCAAAATTGA GGAGAGTGCT 
GAAACACCTG CCCTAGAAGA CTCCTCATCA TCCCCCGTAG ATAGTCAGCA ACATTCCTGG 
CAGGTTTCCA CAGACATTGA GAACACTGAA AGAGACATGA GAGAAATGAA AAACCTTTTA 
AGCAAACTCA GGGAAACTAT GCCTTTACCA TTGAAAAATC AAGATGACAG CAGCCTTCTG 
AATCTAACTC CCTACCCCCT GGTGAGAAGA CGGAAGAGAA GGTTCTTTGG GCTGTGTTGT 
CTCATCTCAA GCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258819.1
CDS	192..566
Translation	MYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS

Target ORF information:

RefSeq Version	NM_001271890.1
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271890.1

ORF Insert Sequence:

ATGTATACCA CAGAGATGCT AAAATCCATA TGTCTGCTGG GGTCTCTTCA GTTTCATCGA 
AAAGGAAAGG AACCTGGCGG GGGAACCAAG AGTTTGGATT GCAAAATTGA GGAGAGTGCT 
GAAACACCTG CCCTAGAAGA CTCCTCATCA TCCCCCGTAG ATAGTCAGCA ACATTCCTGG 
CAGGTTTCCA CAGACATTGA GAACACTGAA AGAGACATGA GAGAAATGAA AAACCTTTTA 
AGCAAACTCA GGGAAACTAT GCCTTTACCA TTGAAAAATC AAGATGACAG CAGCCTTCTG 
AATCTAACTC CCTACCCCCT GGTGAGAAGA CGGAAGAGAA GGTTCTTTGG GCTGTGTTGT 
CTCATCTCAA GCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS7BP ( NM_001271891.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258820.1 Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08673
Clone ID Related Accession (Same CDS sequence)	NM_001271891.1
Accession Version	NM_001271891.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 285bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 7-binding protein isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA211241.1, DC342795.1, AC035143.5, AC008854.3 and BX640900.1. Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1, one of which results in a frameshift. The resulting protein (isoform 3) has a shorter N-terminus and a distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: DC342795.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END##

ATGTATACCA CAGAGATGCT AAAATCCATA TGTCTGCTGG GGTCTCTTCA GTTTCATCGA 
AAAGGAAAGG AACCTGGCGG GGGAACCAAG AGTTTGGATT GCAAAATTGA GGAGAGTGCT 
GAAACACCTG CCCTAGAAGA CTCCTCATCA TCCCCCGTAG ATAGTCAGCA ACATTCCTGG 
CAGGTTTCCA CAGACATTGA GAACACTGAA AGACATGAGA GAAATGAAAA ACCTTTTAAG 
CAAACTCAGG GAAACTATGC CTTTACCATT GAAAAATCAA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258820.1
CDS	192..476
Translation	MYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERHERNEKPFKQTQGNYAFTIEKSR

Target ORF information:

RefSeq Version	NM_001271891.1
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271891.1

ORF Insert Sequence:

ATGTATACCA CAGAGATGCT AAAATCCATA TGTCTGCTGG GGTCTCTTCA GTTTCATCGA 
AAAGGAAAGG AACCTGGCGG GGGAACCAAG AGTTTGGATT GCAAAATTGA GGAGAGTGCT 
GAAACACCTG CCCTAGAAGA CTCCTCATCA TCCCCCGTAG ATAGTCAGCA ACATTCCTGG 
CAGGTTTCCA CAGACATTGA GAACACTGAA AGACATGAGA GAAATGAAAA ACCTTTTAAG 
CAAACTCAGG GAAACTATGC CTTTACCATT GAAAAATCAA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS7BP ( XM_005248502.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248559.1 Homo sapiens regulator of G-protein signaling 7 binding protein (RGS7BP), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu39575
Clone ID Related Accession (Same CDS sequence)	XM_005248502.3 , XM_005248502.4
Accession Version	XM_005248502.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 7-binding protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005248502.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTCTG CACCGAATGG GCGCAAAAAG CGCCCCAGCC GGTCCACCCG CTCCTCGATC 
TTCCAGATCA GCAAGCCCCC GCTGCAGAGC GGAGATTGGG AGCGCAGGGG CAGCGGCTCC 
GAGAGCGCCC ACAAAACCCA ACGAGCCCTG GACGACTGCA AGATGCTTGT CCAAGAGTTC 
AACACACAAG TGGCCCTGTA CCGAGAGCTG GTCATTTCTA TTGGGGATGT CTCGGTCAGC 
TGCCCCTCAC TCCGGGCGGA AATGCACAAG ACAAGAACCA AAGGCTGTGA AATGGCCCGT 
CAGGCACACC AAAAATTGGC TGCCATCTCA GGCCCGGAAG ATGGTGAGAT CCATCCAGAA 
ATCTGTCGGC TTTACATCCA GCTGCAGTGC TGCTTAGAAA TGTATACCAC AGAGATGCTA 
AAATCCATAT GTCTGCTGGG GTCTCTTCAG TTTCATCGAA AAGGAAAGGA ACCTGGCGGG 
GGAACCAAGA GTTTGGATTG CAAAATTGAG GAGAGTGCTG AAACACCTGC CCTAGAAGAC 
TCCTCATCAT CCCCCGTAGA TAGTCAGCAA CATTCCTGGC AGGTTTCCAC AGACATTGAG 
AACACTGAAA GACATGAGAG AAATGAAAAA CCTTTTAAGC AAACTCAGGG AAACTATGCC 
TTTACCATTG AAAAATCAAG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248559.1
CDS	2061..2744
Translation	MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERHERNEKPFKQTQGNYAFTIEKSR

Target ORF information:

RefSeq Version	XM_005248502.3
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G-protein signaling 7 binding protein (RGS7BP), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248502.3

ORF Insert Sequence:

ATGAGTTCTG CACCGAATGG GCGCAAAAAG CGCCCCAGCC GGTCCACCCG CTCCTCGATC 
TTCCAGATCA GCAAGCCCCC GCTGCAGAGC GGAGATTGGG AGCGCAGGGG CAGCGGCTCC 
GAGAGCGCCC ACAAAACCCA ACGAGCCCTG GACGACTGCA AGATGCTTGT CCAAGAGTTC 
AACACACAAG TGGCCCTGTA CCGAGAGCTG GTCATTTCTA TTGGGGATGT CTCGGTCAGC 
TGCCCCTCAC TCCGGGCGGA AATGCACAAG ACAAGAACCA AAGGCTGTGA AATGGCCCGT 
CAGGCACACC AAAAATTGGC TGCCATCTCA GGCCCGGAAG ATGGTGAGAT CCATCCAGAA 
ATCTGTCGGC TTTACATCCA GCTGCAGTGC TGCTTAGAAA TGTATACCAC AGAGATGCTA 
AAATCCATAT GTCTGCTGGG GTCTCTTCAG TTTCATCGAA AAGGAAAGGA ACCTGGCGGG 
GGAACCAAGA GTTTGGATTG CAAAATTGAG GAGAGTGCTG AAACACCTGC CCTAGAAGAC 
TCCTCATCAT CCCCCGTAGA TAGTCAGCAA CATTCCTGGC AGGTTTCCAC AGACATTGAG 
AACACTGAAA GACATGAGAG AAATGAAAAA CCTTTTAAGC AAACTCAGGG AAACTATGCC 
TTTACCATTG AAAAATCAAG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS7BP ( XM_005248502.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248559.1 Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu39575
Clone ID Related Accession (Same CDS sequence)	XM_005248502.3 , XM_005248502.4
Accession Version	XM_005248502.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 7-binding protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005248502.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTCTG CACCGAATGG GCGCAAAAAG CGCCCCAGCC GGTCCACCCG CTCCTCGATC 
TTCCAGATCA GCAAGCCCCC GCTGCAGAGC GGAGATTGGG AGCGCAGGGG CAGCGGCTCC 
GAGAGCGCCC ACAAAACCCA ACGAGCCCTG GACGACTGCA AGATGCTTGT CCAAGAGTTC 
AACACACAAG TGGCCCTGTA CCGAGAGCTG GTCATTTCTA TTGGGGATGT CTCGGTCAGC 
TGCCCCTCAC TCCGGGCGGA AATGCACAAG ACAAGAACCA AAGGCTGTGA AATGGCCCGT 
CAGGCACACC AAAAATTGGC TGCCATCTCA GGCCCGGAAG ATGGTGAGAT CCATCCAGAA 
ATCTGTCGGC TTTACATCCA GCTGCAGTGC TGCTTAGAAA TGTATACCAC AGAGATGCTA 
AAATCCATAT GTCTGCTGGG GTCTCTTCAG TTTCATCGAA AAGGAAAGGA ACCTGGCGGG 
GGAACCAAGA GTTTGGATTG CAAAATTGAG GAGAGTGCTG AAACACCTGC CCTAGAAGAC 
TCCTCATCAT CCCCCGTAGA TAGTCAGCAA CATTCCTGGC AGGTTTCCAC AGACATTGAG 
AACACTGAAA GACATGAGAG AAATGAAAAA CCTTTTAAGC AAACTCAGGG AAACTATGCC 
TTTACCATTG AAAAATCAAG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248559.1
CDS	679..1362
Translation	MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERHERNEKPFKQTQGNYAFTIEKSR

Target ORF information:

RefSeq Version	XM_005248502.4
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 7 binding protein (RGS7BP), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248502.4

ORF Insert Sequence:

ATGAGTTCTG CACCGAATGG GCGCAAAAAG CGCCCCAGCC GGTCCACCCG CTCCTCGATC 
TTCCAGATCA GCAAGCCCCC GCTGCAGAGC GGAGATTGGG AGCGCAGGGG CAGCGGCTCC 
GAGAGCGCCC ACAAAACCCA ACGAGCCCTG GACGACTGCA AGATGCTTGT CCAAGAGTTC 
AACACACAAG TGGCCCTGTA CCGAGAGCTG GTCATTTCTA TTGGGGATGT CTCGGTCAGC 
TGCCCCTCAC TCCGGGCGGA AATGCACAAG ACAAGAACCA AAGGCTGTGA AATGGCCCGT 
CAGGCACACC AAAAATTGGC TGCCATCTCA GGCCCGGAAG ATGGTGAGAT CCATCCAGAA 
ATCTGTCGGC TTTACATCCA GCTGCAGTGC TGCTTAGAAA TGTATACCAC AGAGATGCTA 
AAATCCATAT GTCTGCTGGG GTCTCTTCAG TTTCATCGAA AAGGAAAGGA ACCTGGCGGG 
GGAACCAAGA GTTTGGATTG CAAAATTGAG GAGAGTGCTG AAACACCTGC CCTAGAAGAC 
TCCTCATCAT CCCCCGTAGA TAGTCAGCAA CATTCCTGGC AGGTTTCCAC AGACATTGAG 
AACACTGAAA GACATGAGAG AAATGAAAAA CCTTTTAAGC AAACTCAGGG AAACTATGCC 
TTTACCATTG AAAAATCAAG GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit G?
The Journal of biological chemistry292(24)9906-9918(2017 06)
Scherer SL,Cain MD,Kanai SM,Kaltenbronn KM,Blumer KJ

Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by G?o and R7-binding Protein.
The Journal of biological chemistry291(17)9133-47(2016 Apr)
Tayou J,Wang Q,Jang GF,Pronin AN,Orlandi C,Martemyanov KA,Crabb JW,Slepak VZ

Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology106(4)292-300.e6(2011 Apr)
Lee EH,Park BL,Park SM,Lee SH,Park SW,Park JS,Uh ST,Kim MK,Choi IS,Cho SH,Hong CS,Lee JY,Choi BW,Shin HD,Park CS

RGS11 interacts preferentially with R7BP over Galpha(oa)--characterization of Gbeta5-free RGS11.
Biochemical and biophysical research communications386(1)65-70(2009 Aug)
Saleem Y,Kim KS

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

RGS7BP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報