Gene Symbol | LMO2 |
Entrez Gene ID | 4005 |
Full Name | LIM domain only 2 |
Synonyms | LMO-2,RBTN2,RBTNL1,RHOM2,TTG2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]. |
Disorder MIM: | |
Disorder Html: | Leukemia, acute T-cell (2) |