LMNA gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_011509534.1	XP_011507836.1	lamin isoform X2
NM_001257374.2	NP_001244303.1	lamin isoform D
XM_011509534.2	XP_011507836.1	lamin isoform X2
NM_001282625.1	NP_001269554.1	lamin isoform C
NM_001257374.3	NP_001244303.1	lamin isoform D
NM_170707.3	NP_733821.1	lamin isoform A
NM_001282626.1	NP_001269555.1	lamin isoform A-delta50
XM_011509533.1	XP_011507835.1	lamin isoform X1
NM_170707.4	NP_733821.1	lamin isoform A
NM_005572.3	NP_005563.1	lamin isoform C
NM_170708.3	NP_733822.1	lamin isoform A-delta10
NM_001282626.2	NP_001269555.1	lamin isoform A-delta50
NM_001282624.1	NP_001269553.1	lamin isoform E

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27661	NM_001282626.2 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu16808	NM_005572.3 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
OHu16808	NM_001282625.1 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
OHu21250	NM_170707.4 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
OHu20696	NM_170708.3 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu22769	NM_001257374.3 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu27626	NM_001282624.1 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu58735	XM_011509533.1 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu58736	XM_011509534.2 Latest version!	Homo sapiens lamin A/C (LMNA), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu58736	XM_011509534.1	Homo sapiens lamin A/C (LMNA), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu22769	NM_001257374.2	Homo sapiens lamin A/C (LMNA), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu21250	NM_170707.3	Homo sapiens lamin A/C (LMNA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
OHu27661	NM_001282626.1	Homo sapiens lamin A/C (LMNA), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

LMNA ( NM_001282626.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269555.1 Homo sapiens lamin A/C (LMNA), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu27661
Clone ID Related Accession (Same CDS sequence)	NM_001282626.1 , NM_001282626.2
Accession Version	NM_001282626.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1845bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	lamin isoform A-delta50
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA551594.1, AY357727.1, BU685425.1, BU732343.1 and AI872233.1. Transcript Variant: This variant (7) uses an alternate 3' exon structure and thus differs in the 3' coding region and 3' UTR, compared to variant 1. This results in a shorter isoform (A-delta50, also known as progerin) with a distinct C-terminus when compared to isoform prelamin A. Although this isoform has been linked to Hutchinson-Gilford progeria syndrome, it is also found in unaffected individuals and thought to be linked to cellular terminal differentiation and physiological aging (see PubMed IDs: 12702809, 16645051, and 18060063). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY357727.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGG CTCCCACTGC AGCAGCTCGG GGGACCCCGC TGAGTACAAC 
CTGCGCTCGC GCACCGTGCT GTGCGGGACC TGCGGGCAGC CTGCCGACAA GGCATCTGCC 
AGCGGCTCAG GAGCCCAGAG CCCCCAGAAC TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269555.1
CDS	250..2094
Translation	METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQSPQNCSIM

Target ORF information:

RefSeq Version	NM_001282626.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282626.1

ORF Insert Sequence:

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGG CTCCCACTGC AGCAGCTCGG GGGACCCCGC TGAGTACAAC 
CTGCGCTCGC GCACCGTGCT GTGCGGGACC TGCGGGCAGC CTGCCGACAA GGCATCTGCC 
AGCGGCTCAG GAGCCCAGAG CCCCCAGAAC TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_001282626.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269555.1 Homo sapiens lamin A/C (LMNA), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu27661
Clone ID Related Accession (Same CDS sequence)	NM_001282626.1 , NM_001282626.2
Accession Version	NM_001282626.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1845bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	lamin isoform A-delta50
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA551594.1, AY357727.1, BU685425.1, BU732343.1 and AI872233.1. On May 31, 2019 this sequence version replaced NM_001282626.1. Transcript Variant: This variant (7) uses an alternate 3' exon structure and thus differs in the 3' coding region and 3' UTR, compared to variant 1. This results in a shorter isoform (A-delta50, also known as progerin) with a distinct C-terminus when compared to isoform prelamin A. Although this isoform has been linked to Hutchinson-Gilford progeria syndrome, it is also found in unaffected individuals and thought to be linked to cellular terminal differentiation and physiological aging (see PubMed IDs: 12702809, 16645051, and 18060063). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY357727.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGG CTCCCACTGC AGCAGCTCGG GGGACCCCGC TGAGTACAAC 
CTGCGCTCGC GCACCGTGCT GTGCGGGACC TGCGGGCAGC CTGCCGACAA GGCATCTGCC 
AGCGGCTCAG GAGCCCAGAG CCCCCAGAAC TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269555.1
CDS	209..2053
Translation	METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQSPQNCSIM

Target ORF information:

RefSeq Version	NM_001282626.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282626.2

ORF Insert Sequence:

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGG CTCCCACTGC AGCAGCTCGG GGGACCCCGC TGAGTACAAC 
CTGCGCTCGC GCACCGTGCT GTGCGGGACC TGCGGGCAGC CTGCCGACAA GGCATCTGCC 
AGCGGCTCAG GAGCCCAGAG CCCCCAGAAC TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_001282625.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269554.1 Homo sapiens lamin A/C (LMNA), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu16808
Clone ID Related Accession (Same CDS sequence)	NM_001282625.1 , NM_005572.3
Accession Version	NM_001282625.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	lamin isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB270595.1, AK056143.1 and BC000511.2. On Sep 17, 2013 this sequence version replaced NR_047544.1. Transcript Variant: This variant (6) differs in both UTRs and has multiple differences in the coding region compared to variant 1. This results in a shorter isoform (C) with a distinct C-terminus when compared to isoform prelamin A. Both variants 2 and 6 encode the same isoform (C). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK056143.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGT GAGTGGTAGC CGCCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269554.1
CDS	674..2392
Translation	METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHVSGSRR

Target ORF information:

RefSeq Version	NM_001282625.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282625.1

ORF Insert Sequence:

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGT GAGTGGTAGC CGCCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_005572.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005563.1 Homo sapiens lamin A/C (LMNA), transcript variant 2, mRNA.

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CloneID	OHu16808
Clone ID Related Accession (Same CDS sequence)	NM_001282625.1 , NM_005572.3
Accession Version	NM_005572.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	lamin isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA421696.1, X03445.1 and AA558657.1. This sequence is a reference standard in the RefSeqGene project. On Jul 24, 2007 this sequence version replaced NM_005572.2. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1. This results in a shorter isoform (C) with a distinct C-terminus when compared to isoform prelamin A. Both variants 2 and 6 encode the same isoform (C). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.305657.1, X03445.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGT GAGTGGTAGC CGCCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005563.1
CDS	250..1968
Translation	METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHVSGSRR

Target ORF information:

RefSeq Version	NM_005572.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005572.3

ORF Insert Sequence:

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGT GAGTGGTAGC CGCCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_170707.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_733821.1 Homo sapiens lamin A/C (LMNA), transcript variant 1, mRNA.

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CloneID	OHu21250
Clone ID Related Accession (Same CDS sequence)	NM_170707.3 , NM_170707.4
Accession Version	NM_170707.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	lamin isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG822820.1, BC014507.1, AL135927.14 and AI872233.1. On Apr 10, 2012 this sequence version replaced NM_170707.2. Transcript Variant: This variant (1) encodes isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK026584.1, BC014507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGG CTCCCACTGC AGCAGCTCGG GGGACCCCGC TGAGTACAAC 
CTGCGCTCGC GCACCGTGCT GTGCGGGACC TGCGGGCAGC CTGCCGACAA GGCATCTGCC 
AGCGGCTCAG GAGCCCAGGT GGGCGGACCC ATCTCCTCTG GCTCTTCTGC CTCCAGTGTC 
ACGGTCACTC GCAGCTACCG CAGTGTGGGG GGCAGTGGGG GTGGCAGCTT CGGGGACAAT 
CTGGTCACCC GCTCCTACCT CCTGGGCAAC TCCAGCCCCC GAACCCAGAG CCCCCAGAAC 
TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_733821.1
CDS	250..2244
Translation	METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM

Target ORF information:

RefSeq Version	NM_170707.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170707.3

ORF Insert Sequence:

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGG CTCCCACTGC AGCAGCTCGG GGGACCCCGC TGAGTACAAC 
CTGCGCTCGC GCACCGTGCT GTGCGGGACC TGCGGGCAGC CTGCCGACAA GGCATCTGCC 
AGCGGCTCAG GAGCCCAGGT GGGCGGACCC ATCTCCTCTG GCTCTTCTGC CTCCAGTGTC 
ACGGTCACTC GCAGCTACCG CAGTGTGGGG GGCAGTGGGG GTGGCAGCTT CGGGGACAAT 
CTGGTCACCC GCTCCTACCT CCTGGGCAAC TCCAGCCCCC GAACCCAGAG CCCCCAGAAC 
TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_170707.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_733821.1 Homo sapiens lamin A/C (LMNA), transcript variant 1, mRNA.

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CloneID	OHu21250
Clone ID Related Accession (Same CDS sequence)	NM_170707.3 , NM_170707.4
Accession Version	NM_170707.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	lamin isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG822820.1, BC014507.1, AL135927.14 and AI872233.1. On Nov 23, 2018 this sequence version replaced NM_170707.3. Transcript Variant: This variant (1) encodes isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.401940.1, SRR3476690.1068249.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000368300.9/ ENSP00000357283.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGG CTCCCACTGC AGCAGCTCGG GGGACCCCGC TGAGTACAAC 
CTGCGCTCGC GCACCGTGCT GTGCGGGACC TGCGGGCAGC CTGCCGACAA GGCATCTGCC 
AGCGGCTCAG GAGCCCAGGT GGGCGGACCC ATCTCCTCTG GCTCTTCTGC CTCCAGTGTC 
ACGGTCACTC GCAGCTACCG CAGTGTGGGG GGCAGTGGGG GTGGCAGCTT CGGGGACAAT 
CTGGTCACCC GCTCCTACCT CCTGGGCAAC TCCAGCCCCC GAACCCAGAG CCCCCAGAAC 
TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_733821.1
CDS	209..2203
Translation	METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM

Target ORF information:

RefSeq Version	NM_170707.4
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170707.4

ORF Insert Sequence:

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGA AGTGGCCATG 
CGCAAGCTGG TGCGCTCAGT GACTGTGGTT GAGGACGACG AGGATGAGGA TGGAGATGAC 
CTGCTCCATC ACCACCACGG CTCCCACTGC AGCAGCTCGG GGGACCCCGC TGAGTACAAC 
CTGCGCTCGC GCACCGTGCT GTGCGGGACC TGCGGGCAGC CTGCCGACAA GGCATCTGCC 
AGCGGCTCAG GAGCCCAGGT GGGCGGACCC ATCTCCTCTG GCTCTTCTGC CTCCAGTGTC 
ACGGTCACTC GCAGCTACCG CAGTGTGGGG GGCAGTGGGG GTGGCAGCTT CGGGGACAAT 
CTGGTCACCC GCTCCTACCT CCTGGGCAAC TCCAGCCCCC GAACCCAGAG CCCCCAGAAC 
TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_170708.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_733822.1 Homo sapiens lamin A/C (LMNA), transcript variant 3, mRNA.

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CloneID	OHu20696
Clone ID Related Accession (Same CDS sequence)	NM_170708.3
Accession Version	NM_170708.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1905bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	lamin isoform A-delta10
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG822820.1, BC000511.2, AF381029.1, BC014507.1, AL135927.14 and AI872233.1. On Apr 10, 2012 this sequence version replaced NM_170708.2. Transcript Variant: This variant (3) lacks an internal segment of sequence compared to variant 1. The encoded isoform (A delta10), is shorter but has the same C-terminus when compared to isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.262170.1, SRR1803611.195689.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGG CTCCCACTGC 
AGCAGCTCGG GGGACCCCGC TGAGTACAAC CTGCGCTCGC GCACCGTGCT GTGCGGGACC 
TGCGGGCAGC CTGCCGACAA GGCATCTGCC AGCGGCTCAG GAGCCCAGGT GGGCGGACCC 
ATCTCCTCTG GCTCTTCTGC CTCCAGTGTC ACGGTCACTC GCAGCTACCG CAGTGTGGGG 
GGCAGTGGGG GTGGCAGCTT CGGGGACAAT CTGGTCACCC GCTCCTACCT CCTGGGCAAC 
TCCAGCCCCC GAACCCAGAG CCCCCAGAAC TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_733822.1
CDS	250..2154
Translation	METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM

Target ORF information:

RefSeq Version	NM_170708.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170708.3

ORF Insert Sequence:

ATGGAGACCC CGTCCCAGCG GCGCGCCACC CGCAGCGGGG CGCAGGCCAG CTCCACTCCG 
CTGTCGCCCA CCCGCATCAC CCGGCTGCAG GAGAAGGAGG ACCTGCAGGA GCTCAATGAT 
CGCTTGGCGG TCTACATCGA CCGTGTGCGC TCGCTGGAAA CGGAGAACGC AGGGCTGCGC 
CTTCGCATCA CCGAGTCTGA AGAGGTGGTC AGCCGCGAGG TGTCCGGCAT CAAGGCCGCC 
TACGAGGCCG AGCTCGGGGA TGCCCGCAAG ACCCTTGACT CAGTAGCCAA GGAGCGCGCC 
CGCCTGCAGC TGGAGCTGAG CAAAGTGCGT GAGGAGTTTA AGGAGCTGAA AGCGCGCAAT 
ACCAAGAAGG AGGGTGACCT GATAGCTGCT CAGGCTCGGC TGAAGGACCT GGAGGCTCTG 
CTGAACTCCA AGGAGGCCGC ACTGAGCACT GCTCTCAGTG AGAAGCGCAC GCTGGAGGGC 
GAGCTGCATG ATCTGCGGGG CCAGGTGGCC AAGCTTGAGG CAGCCCTAGG TGAGGCCAAG 
AAGCAACTTC AGGATGAGAT GCTGCGGCGG GTGGATGCTG AGAACAGGCT GCAGACCATG 
AAGGAGGAAC TGGACTTCCA GAAGAACATC TACAGTGAGG AGCTGCGTGA GACCAAGCGC 
CGTCATGAGA CCCGACTGGT GGAGATTGAC AATGGGAAGC AGCGTGAGTT TGAGAGCCGG 
CTGGCGGATG CGCTGCAGGA ACTGCGGGCC CAGCATGAGG ACCAGGTGGA GCAGTATAAG 
AAGGAGCTGG AGAAGACTTA TTCTGCCAAG CTGGACAATG CCAGGCAGTC TGCTGAGAGG 
AACAGCAACC TGGTGGGGGC TGCCCACGAG GAGCTGCAGC AGTCGCGCAT CCGCATCGAC 
AGCCTCTCTG CCCAGCTCAG CCAGCTCCAG AAGCAGCTGG CAGCCAAGGA GGCGAAGCTT 
CGAGACCTGG AGGACTCACT GGCCCGTGAG CGGGACACCA GCCGGCGGCT GCTGGCGGAA 
AAGGAGCGGG AGATGGCCGA GATGCGGGCA AGGATGCAGC AGCAGCTGGA CGAGTACCAG 
GAGCTTCTGG ACATCAAGCT GGCCCTGGAC ATGGAGATCC ACGCCTACCG CAAGCTCTTG 
GAGGGCGAGG AGGAGAGGCT ACGCCTGTCC CCCAGCCCTA CCTCGCAGCG CAGCCGTGGC 
CGTGCTTCCT CTCACTCATC CCAGACACAG GGTGGGGGCA GCGTCACCAA AAAGCGCAAA 
CTGGAGTCCA CTGAGAGCCG CAGCAGCTTC TCACAGCACG CACGCACTAG CGGGCGCGTG 
GCCGTGGAGG AGGTGGATGA GGAGGGCAAG TTTGTCCGGC TGCGCAACAA GTCCAATGAG 
GACCAGTCCA TGGGCAATTG GCAGATCAAG CGCCAGAATG GAGATGATCC CTTGCTGACT 
TACCGGTTCC CACCAAAGTT CACCCTGAAG GCTGGGCAGG TGGTGACGAT CTGGGCTGCA 
GGAGCTGGGG CCACCCACAG CCCCCCTACC GACCTGGTGT GGAAGGCACA GAACACCTGG 
GGCTGCGGGA ACAGCCTGCG TACGGCTCTC ATCAACTCCA CTGGGGAAGG CTCCCACTGC 
AGCAGCTCGG GGGACCCCGC TGAGTACAAC CTGCGCTCGC GCACCGTGCT GTGCGGGACC 
TGCGGGCAGC CTGCCGACAA GGCATCTGCC AGCGGCTCAG GAGCCCAGGT GGGCGGACCC 
ATCTCCTCTG GCTCTTCTGC CTCCAGTGTC ACGGTCACTC GCAGCTACCG CAGTGTGGGG 
GGCAGTGGGG GTGGCAGCTT CGGGGACAAT CTGGTCACCC GCTCCTACCT CCTGGGCAAC 
TCCAGCCCCC GAACCCAGAG CCCCCAGAAC TGCAGCATCA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_001257374.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001244303.1 Homo sapiens lamin A/C (LMNA), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu22769
Clone ID Related Accession (Same CDS sequence)	NM_001257374.2 , NM_001257374.3
Accession Version	NM_001257374.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	lamin isoform D
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY027676.1, AK295390.1, BC018863.2, AL135927.14 and AI872233.1. On Sep 17, 2013 this sequence version replaced NM_001257374.1. Transcript Variant: This variant (4) represents use of an alternate promoter and uses an alternate 3' exon structure compared to variant 1. The resulting protein (isoform D) has distinct N- and C-termini and is shorter than isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295390.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2146982 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAACT CTGAGGGCTG CAATACCAAG AAGGAGGGTG ACCTGATAGC TGCTCAGGCT 
CGGCTGAAGG ACCTGGAGGC TCTGCTGAAC TCCAAGGAGG CCGCACTGAG CACTGCTCTC 
AGTGAGAAGC GCACGCTGGA GGGCGAGCTG CATGATCTGC GGGGCCAGGT GGCCAAGCTT 
GAGGCAGCCC TAGGTGAGGC CAAGAAGCAA CTTCAGGATG AGATGCTGCG GCGGGTGGAT 
GCTGAGAACA GGCTGCAGAC CATGAAGGAG GAACTGGACT TCCAGAAGAA CATCTACAGT 
GAGGAGCTGC GTGAGACCAA GCGCCGTCAT GAGACCCGAC TGGTGGAGAT TGACAATGGG 
AAGCAGCGTG AGTTTGAGAG CCGGCTGGCG GATGCGCTGC AGGAACTGCG GGCCCAGCAT 
GAGGACCAGG TGGAGCAGTA TAAGAAGGAG CTGGAGAAGA CTTATTCTGC CAAGCTGGAC 
AATGCCAGGC AGTCTGCTGA GAGGAACAGC AACCTGGTGG GGGCTGCCCA CGAGGAGCTG 
CAGCAGTCGC GCATCCGCAT CGACAGCCTC TCTGCCCAGC TCAGCCAGCT CCAGAAGCAG 
CTGGCAGCCA AGGAGGCGAA GCTTCGAGAC CTGGAGGACT CACTGGCCCG TGAGCGGGAC 
ACCAGCCGGC GGCTGCTGGC GGAAAAGGAG CGGGAGATGG CCGAGATGCG GGCAAGGATG 
CAGCAGCAGC TGGACGAGTA CCAGGAGCTT CTGGACATCA AGCTGGCCCT GGACATGGAG 
ATCCACGCCT ACCGCAAGCT CTTGGAGGGC GAGGAGGAGA GGCTACGCCT GTCCCCCAGC 
CCTACCTCGC AGCGCAGCCG TGGCCGTGCT TCCTCTCACT CATCCCAGAC ACAGGGTGGG 
GGCAGCGTCA CCAAAAAGCG CAAACTGGAG TCCACTGAGA GCCGCAGCAG CTTCTCACAG 
CACGCACGCA CTAGCGGGCG CGTGGCCGTG GAGGAGGTGG ATGAGGAGGG CAAGTTTGTC 
CGGCTGCGCA ACAAGTCCAA TGAGGACCAG TCCATGGGCA ATTGGCAGAT CAAGCGCCAG 
AATGGAGATG ATCCCTTGCT GACTTACCGG TTCCCACCAA AGTTCACCCT GAAGGCTGGG 
CAGGTGGTGA CGATCTGGGC TGCAGGAGCT GGGGCCACCC ACAGCCCCCC TACCGACCTG 
GTGTGGAAGG CACAGAACAC CTGGGGCTGC GGGAACAGCC TGCGTACGGC TCTCATCAAC 
TCCACTGGGG AAGAAGTGGC CATGCGCAAG CTGGTGCGCT CAGTGACTGT GGTTGAGGAC 
GACGAGGATG AGGATGGAGA TGACCTGCTC CATCACCACC ACGGCTCCCA CTGCAGCAGC 
TCGGGGGACC CCGCTGAGTA CAACCTGCGC TCGCGCACCG TGCTGTGCGG GACCTGCGGG 
CAGCCTGCCG ACAAGGCATC TGCCAGCGGC TCAGGAGCCC AGGTGGGCGG ACCCATCTCC 
TCTGGCTCTT CTGCCTCCAG TGTCACGGTC ACTCGCAGCT ACCGCAGTGT GGGGGGCAGT 
GGGGGTGGCA GCTTCGGGGA CAATCTGGTC ACCCGCTCCT ACCTCCTGGG CAACTCCAGC 
CCCCGAACCC AGAGCCCCCA GAACTGCAGC ATCATACAAG AGATGGGAAT GAGGTGGGAG 
GTGGAAGAAG GGAGAAGAAA GGTGAGTTTG AGCTGCCTTC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244303.1
CDS	88..1812
Translation	MGNSEGCNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIIQEMGMRWEVEEGRRKVSLSCLP

Target ORF information:

RefSeq Version	NM_001257374.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257374.2

ORF Insert Sequence:

ATGGGGAACT CTGAGGGCTG CAATACCAAG AAGGAGGGTG ACCTGATAGC TGCTCAGGCT 
CGGCTGAAGG ACCTGGAGGC TCTGCTGAAC TCCAAGGAGG CCGCACTGAG CACTGCTCTC 
AGTGAGAAGC GCACGCTGGA GGGCGAGCTG CATGATCTGC GGGGCCAGGT GGCCAAGCTT 
GAGGCAGCCC TAGGTGAGGC CAAGAAGCAA CTTCAGGATG AGATGCTGCG GCGGGTGGAT 
GCTGAGAACA GGCTGCAGAC CATGAAGGAG GAACTGGACT TCCAGAAGAA CATCTACAGT 
GAGGAGCTGC GTGAGACCAA GCGCCGTCAT GAGACCCGAC TGGTGGAGAT TGACAATGGG 
AAGCAGCGTG AGTTTGAGAG CCGGCTGGCG GATGCGCTGC AGGAACTGCG GGCCCAGCAT 
GAGGACCAGG TGGAGCAGTA TAAGAAGGAG CTGGAGAAGA CTTATTCTGC CAAGCTGGAC 
AATGCCAGGC AGTCTGCTGA GAGGAACAGC AACCTGGTGG GGGCTGCCCA CGAGGAGCTG 
CAGCAGTCGC GCATCCGCAT CGACAGCCTC TCTGCCCAGC TCAGCCAGCT CCAGAAGCAG 
CTGGCAGCCA AGGAGGCGAA GCTTCGAGAC CTGGAGGACT CACTGGCCCG TGAGCGGGAC 
ACCAGCCGGC GGCTGCTGGC GGAAAAGGAG CGGGAGATGG CCGAGATGCG GGCAAGGATG 
CAGCAGCAGC TGGACGAGTA CCAGGAGCTT CTGGACATCA AGCTGGCCCT GGACATGGAG 
ATCCACGCCT ACCGCAAGCT CTTGGAGGGC GAGGAGGAGA GGCTACGCCT GTCCCCCAGC 
CCTACCTCGC AGCGCAGCCG TGGCCGTGCT TCCTCTCACT CATCCCAGAC ACAGGGTGGG 
GGCAGCGTCA CCAAAAAGCG CAAACTGGAG TCCACTGAGA GCCGCAGCAG CTTCTCACAG 
CACGCACGCA CTAGCGGGCG CGTGGCCGTG GAGGAGGTGG ATGAGGAGGG CAAGTTTGTC 
CGGCTGCGCA ACAAGTCCAA TGAGGACCAG TCCATGGGCA ATTGGCAGAT CAAGCGCCAG 
AATGGAGATG ATCCCTTGCT GACTTACCGG TTCCCACCAA AGTTCACCCT GAAGGCTGGG 
CAGGTGGTGA CGATCTGGGC TGCAGGAGCT GGGGCCACCC ACAGCCCCCC TACCGACCTG 
GTGTGGAAGG CACAGAACAC CTGGGGCTGC GGGAACAGCC TGCGTACGGC TCTCATCAAC 
TCCACTGGGG AAGAAGTGGC CATGCGCAAG CTGGTGCGCT CAGTGACTGT GGTTGAGGAC 
GACGAGGATG AGGATGGAGA TGACCTGCTC CATCACCACC ACGGCTCCCA CTGCAGCAGC 
TCGGGGGACC CCGCTGAGTA CAACCTGCGC TCGCGCACCG TGCTGTGCGG GACCTGCGGG 
CAGCCTGCCG ACAAGGCATC TGCCAGCGGC TCAGGAGCCC AGGTGGGCGG ACCCATCTCC 
TCTGGCTCTT CTGCCTCCAG TGTCACGGTC ACTCGCAGCT ACCGCAGTGT GGGGGGCAGT 
GGGGGTGGCA GCTTCGGGGA CAATCTGGTC ACCCGCTCCT ACCTCCTGGG CAACTCCAGC 
CCCCGAACCC AGAGCCCCCA GAACTGCAGC ATCATACAAG AGATGGGAAT GAGGTGGGAG 
GTGGAAGAAG GGAGAAGAAA GGTGAGTTTG AGCTGCCTTC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_001257374.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001244303.1 Homo sapiens lamin A/C (LMNA), transcript variant 4, mRNA.

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CloneID	OHu22769
Clone ID Related Accession (Same CDS sequence)	NM_001257374.2 , NM_001257374.3
Accession Version	NM_001257374.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	lamin isoform D
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK295390.1, BC018863.2, AL135927.14 and AI872233.1. On May 31, 2019 this sequence version replaced NM_001257374.2. Transcript Variant: This variant (4) represents use of an alternate promoter and uses an alternate 3' exon structure compared to variant 1. The resulting protein (isoform D) has distinct N- and C-termini and is shorter than isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295390.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2146982 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAACT CTGAGGGCTG CAATACCAAG AAGGAGGGTG ACCTGATAGC TGCTCAGGCT 
CGGCTGAAGG ACCTGGAGGC TCTGCTGAAC TCCAAGGAGG CCGCACTGAG CACTGCTCTC 
AGTGAGAAGC GCACGCTGGA GGGCGAGCTG CATGATCTGC GGGGCCAGGT GGCCAAGCTT 
GAGGCAGCCC TAGGTGAGGC CAAGAAGCAA CTTCAGGATG AGATGCTGCG GCGGGTGGAT 
GCTGAGAACA GGCTGCAGAC CATGAAGGAG GAACTGGACT TCCAGAAGAA CATCTACAGT 
GAGGAGCTGC GTGAGACCAA GCGCCGTCAT GAGACCCGAC TGGTGGAGAT TGACAATGGG 
AAGCAGCGTG AGTTTGAGAG CCGGCTGGCG GATGCGCTGC AGGAACTGCG GGCCCAGCAT 
GAGGACCAGG TGGAGCAGTA TAAGAAGGAG CTGGAGAAGA CTTATTCTGC CAAGCTGGAC 
AATGCCAGGC AGTCTGCTGA GAGGAACAGC AACCTGGTGG GGGCTGCCCA CGAGGAGCTG 
CAGCAGTCGC GCATCCGCAT CGACAGCCTC TCTGCCCAGC TCAGCCAGCT CCAGAAGCAG 
CTGGCAGCCA AGGAGGCGAA GCTTCGAGAC CTGGAGGACT CACTGGCCCG TGAGCGGGAC 
ACCAGCCGGC GGCTGCTGGC GGAAAAGGAG CGGGAGATGG CCGAGATGCG GGCAAGGATG 
CAGCAGCAGC TGGACGAGTA CCAGGAGCTT CTGGACATCA AGCTGGCCCT GGACATGGAG 
ATCCACGCCT ACCGCAAGCT CTTGGAGGGC GAGGAGGAGA GGCTACGCCT GTCCCCCAGC 
CCTACCTCGC AGCGCAGCCG TGGCCGTGCT TCCTCTCACT CATCCCAGAC ACAGGGTGGG 
GGCAGCGTCA CCAAAAAGCG CAAACTGGAG TCCACTGAGA GCCGCAGCAG CTTCTCACAG 
CACGCACGCA CTAGCGGGCG CGTGGCCGTG GAGGAGGTGG ATGAGGAGGG CAAGTTTGTC 
CGGCTGCGCA ACAAGTCCAA TGAGGACCAG TCCATGGGCA ATTGGCAGAT CAAGCGCCAG 
AATGGAGATG ATCCCTTGCT GACTTACCGG TTCCCACCAA AGTTCACCCT GAAGGCTGGG 
CAGGTGGTGA CGATCTGGGC TGCAGGAGCT GGGGCCACCC ACAGCCCCCC TACCGACCTG 
GTGTGGAAGG CACAGAACAC CTGGGGCTGC GGGAACAGCC TGCGTACGGC TCTCATCAAC 
TCCACTGGGG AAGAAGTGGC CATGCGCAAG CTGGTGCGCT CAGTGACTGT GGTTGAGGAC 
GACGAGGATG AGGATGGAGA TGACCTGCTC CATCACCACC ACGGCTCCCA CTGCAGCAGC 
TCGGGGGACC CCGCTGAGTA CAACCTGCGC TCGCGCACCG TGCTGTGCGG GACCTGCGGG 
CAGCCTGCCG ACAAGGCATC TGCCAGCGGC TCAGGAGCCC AGGTGGGCGG ACCCATCTCC 
TCTGGCTCTT CTGCCTCCAG TGTCACGGTC ACTCGCAGCT ACCGCAGTGT GGGGGGCAGT 
GGGGGTGGCA GCTTCGGGGA CAATCTGGTC ACCCGCTCCT ACCTCCTGGG CAACTCCAGC 
CCCCGAACCC AGAGCCCCCA GAACTGCAGC ATCATACAAG AGATGGGAAT GAGGTGGGAG 
GTGGAAGAAG GGAGAAGAAA GGTGAGTTTG AGCTGCCTTC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244303.1
CDS	35..1759
Translation	MGNSEGCNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIIQEMGMRWEVEEGRRKVSLSCLP

Target ORF information:

RefSeq Version	NM_001257374.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257374.3

ORF Insert Sequence:

ATGGGGAACT CTGAGGGCTG CAATACCAAG AAGGAGGGTG ACCTGATAGC TGCTCAGGCT 
CGGCTGAAGG ACCTGGAGGC TCTGCTGAAC TCCAAGGAGG CCGCACTGAG CACTGCTCTC 
AGTGAGAAGC GCACGCTGGA GGGCGAGCTG CATGATCTGC GGGGCCAGGT GGCCAAGCTT 
GAGGCAGCCC TAGGTGAGGC CAAGAAGCAA CTTCAGGATG AGATGCTGCG GCGGGTGGAT 
GCTGAGAACA GGCTGCAGAC CATGAAGGAG GAACTGGACT TCCAGAAGAA CATCTACAGT 
GAGGAGCTGC GTGAGACCAA GCGCCGTCAT GAGACCCGAC TGGTGGAGAT TGACAATGGG 
AAGCAGCGTG AGTTTGAGAG CCGGCTGGCG GATGCGCTGC AGGAACTGCG GGCCCAGCAT 
GAGGACCAGG TGGAGCAGTA TAAGAAGGAG CTGGAGAAGA CTTATTCTGC CAAGCTGGAC 
AATGCCAGGC AGTCTGCTGA GAGGAACAGC AACCTGGTGG GGGCTGCCCA CGAGGAGCTG 
CAGCAGTCGC GCATCCGCAT CGACAGCCTC TCTGCCCAGC TCAGCCAGCT CCAGAAGCAG 
CTGGCAGCCA AGGAGGCGAA GCTTCGAGAC CTGGAGGACT CACTGGCCCG TGAGCGGGAC 
ACCAGCCGGC GGCTGCTGGC GGAAAAGGAG CGGGAGATGG CCGAGATGCG GGCAAGGATG 
CAGCAGCAGC TGGACGAGTA CCAGGAGCTT CTGGACATCA AGCTGGCCCT GGACATGGAG 
ATCCACGCCT ACCGCAAGCT CTTGGAGGGC GAGGAGGAGA GGCTACGCCT GTCCCCCAGC 
CCTACCTCGC AGCGCAGCCG TGGCCGTGCT TCCTCTCACT CATCCCAGAC ACAGGGTGGG 
GGCAGCGTCA CCAAAAAGCG CAAACTGGAG TCCACTGAGA GCCGCAGCAG CTTCTCACAG 
CACGCACGCA CTAGCGGGCG CGTGGCCGTG GAGGAGGTGG ATGAGGAGGG CAAGTTTGTC 
CGGCTGCGCA ACAAGTCCAA TGAGGACCAG TCCATGGGCA ATTGGCAGAT CAAGCGCCAG 
AATGGAGATG ATCCCTTGCT GACTTACCGG TTCCCACCAA AGTTCACCCT GAAGGCTGGG 
CAGGTGGTGA CGATCTGGGC TGCAGGAGCT GGGGCCACCC ACAGCCCCCC TACCGACCTG 
GTGTGGAAGG CACAGAACAC CTGGGGCTGC GGGAACAGCC TGCGTACGGC TCTCATCAAC 
TCCACTGGGG AAGAAGTGGC CATGCGCAAG CTGGTGCGCT CAGTGACTGT GGTTGAGGAC 
GACGAGGATG AGGATGGAGA TGACCTGCTC CATCACCACC ACGGCTCCCA CTGCAGCAGC 
TCGGGGGACC CCGCTGAGTA CAACCTGCGC TCGCGCACCG TGCTGTGCGG GACCTGCGGG 
CAGCCTGCCG ACAAGGCATC TGCCAGCGGC TCAGGAGCCC AGGTGGGCGG ACCCATCTCC 
TCTGGCTCTT CTGCCTCCAG TGTCACGGTC ACTCGCAGCT ACCGCAGTGT GGGGGGCAGT 
GGGGGTGGCA GCTTCGGGGA CAATCTGGTC ACCCGCTCCT ACCTCCTGGG CAACTCCAGC 
CCCCGAACCC AGAGCCCCCA GAACTGCAGC ATCATACAAG AGATGGGAAT GAGGTGGGAG 
GTGGAAGAAG GGAGAAGAAA GGTGAGTTTG AGCTGCCTTC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( NM_001282624.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269553.1 Homo sapiens lamin A/C (LMNA), transcript variant 5, mRNA.

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CloneID	OHu27626
Clone ID Related Accession (Same CDS sequence)	NM_001282624.1
Accession Version	NM_001282624.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	lamin isoform E
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY027676.1, AK097801.1 and BC000511.2. On Sep 17, 2013 this sequence version replaced NR_047545.1. Transcript Variant: This variant (5) differs in both UTRs and has multiple differences in the coding region compared to variant 1. This variant encodes isoform E, which is shorter and has distinct N- and C-termini compared to isoform prelamin A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK097801.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCCAC TCCTGTGCTT GGGGAACCTG GAGGATGCAA GGGAAAGGAC TGGCACTCTG 
CTGGCACAGC ACCCGGCCTG GGGCAGGACA CGGGCGAAGC CAGGGTCTCC CCTCAATACC 
AAGAAGGAGG GTGACCTGAT AGCTGCTCAG GCTCGGCTGA AGGACCTGGA GGCTCTGCTG 
AACTCCAAGG AGGCCGCACT GAGCACTGCT CTCAGTGAGA AGCGCACGCT GGAGGGCGAG 
CTGCATGATC TGCGGGGCCA GGTGGCCAAG CTTGAGGCAG CCCTAGGTGA GGCCAAGAAG 
CAACTTCAGG ATGAGATGCT GCGGCGGGTG GATGCTGAGA ACAGGCTGCA GACCATGAAG 
GAGGAACTGG ACTTCCAGAA GAACATCTAC AGTGAGGAGC TGCGTGAGAC CAAGCGCCGT 
CATGAGACCC GACTGGTGGA GATTGACAAT GGGAAGCAGC GTGAGTTTGA GAGCCGGCTG 
GCGGATGCGC TGCAGGAACT GCGGGCCCAG CATGAGGACC AGGTGGAGCA GTATAAGAAG 
GAGCTGGAGA AGACTTATTC TGCCAAGCTG GACAATGCCA GGCAGTCTGC TGAGAGGAAC 
AGCAACCTGG TGGGGGCTGC CCACGAGGAG CTGCAGCAGT CGCGCATCCG CATCGACAGC 
CTCTCTGCCC AGCTCAGCCA GCTCCAGAAG CAGCTGGCAG CCAAGGAGGC GAAGCTTCGA 
GACCTGGAGG ACTCACTGGC CCGTGAGCGG GACACCAGCC GGCGGCTGCT GGCGGAAAAG 
GAGCGGGAGA TGGCCGAGAT GCGGGCAAGG ATGCAGCAGC AGCTGGACGA GTACCAGGAG 
CTTCTGGACA TCAAGCTGGC CCTGGACATG GAGATCCACG CCTACCGCAA GCTCTTGGAG 
GGCGAGGAGG AGAGGCTACG CCTGTCCCCC AGCCCTACCT CGCAGCGCAG CCGTGGCCGT 
GCTTCCTCTC ACTCATCCCA GACACAGGGT GGGGGCAGCG TCACCAAAAA GCGCAAACTG 
GAGTCCACTG AGAGCCGCAG CAGCTTCTCA CAGCACGCAC GCACTAGCGG GCGCGTGGCC 
GTGGAGGAGG TGGATGAGGA GGGCAAGTTT GTCCGGCTGC GCAACAAGTC CAATGAGGAC 
CAGTCCATGG GCAATTGGCA GATCAAGCGC CAGAATGGAG ATGATCCCTT GCTGACTTAC 
CGGTTCCCAC CAAAGTTCAC CCTGAAGGCT GGGCAGGTGG TGACGATCTG GGCTGCAGGA 
GCTGGGGCCA CCCACAGCCC CCCTACCGAC CTGGTGTGGA AGGCACAGAA CACCTGGGGC 
TGCGGGAACA GCCTGCGTAC GGCTCTCATC AACTCCACTG GGGAAGAAGT GGCCATGCGC 
AAGCTGGTGC GCTCAGTGAC TGTGGTTGAG GACGACGAGG ATGAGGATGG AGATGACCTG 
CTCCATCACC ACCACGTGAG TGGTAGCCGC CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269553.1
CDS	175..1650
Translation	MQPLLCLGNLEDARERTGTLLAQHPAWGRTRAKPGSPLNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHVSGSRR

Target ORF information:

RefSeq Version	NM_001282624.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282624.1

ORF Insert Sequence:

ATGCAGCCAC TCCTGTGCTT GGGGAACCTG GAGGATGCAA GGGAAAGGAC TGGCACTCTG 
CTGGCACAGC ACCCGGCCTG GGGCAGGACA CGGGCGAAGC CAGGGTCTCC CCTCAATACC 
AAGAAGGAGG GTGACCTGAT AGCTGCTCAG GCTCGGCTGA AGGACCTGGA GGCTCTGCTG 
AACTCCAAGG AGGCCGCACT GAGCACTGCT CTCAGTGAGA AGCGCACGCT GGAGGGCGAG 
CTGCATGATC TGCGGGGCCA GGTGGCCAAG CTTGAGGCAG CCCTAGGTGA GGCCAAGAAG 
CAACTTCAGG ATGAGATGCT GCGGCGGGTG GATGCTGAGA ACAGGCTGCA GACCATGAAG 
GAGGAACTGG ACTTCCAGAA GAACATCTAC AGTGAGGAGC TGCGTGAGAC CAAGCGCCGT 
CATGAGACCC GACTGGTGGA GATTGACAAT GGGAAGCAGC GTGAGTTTGA GAGCCGGCTG 
GCGGATGCGC TGCAGGAACT GCGGGCCCAG CATGAGGACC AGGTGGAGCA GTATAAGAAG 
GAGCTGGAGA AGACTTATTC TGCCAAGCTG GACAATGCCA GGCAGTCTGC TGAGAGGAAC 
AGCAACCTGG TGGGGGCTGC CCACGAGGAG CTGCAGCAGT CGCGCATCCG CATCGACAGC 
CTCTCTGCCC AGCTCAGCCA GCTCCAGAAG CAGCTGGCAG CCAAGGAGGC GAAGCTTCGA 
GACCTGGAGG ACTCACTGGC CCGTGAGCGG GACACCAGCC GGCGGCTGCT GGCGGAAAAG 
GAGCGGGAGA TGGCCGAGAT GCGGGCAAGG ATGCAGCAGC AGCTGGACGA GTACCAGGAG 
CTTCTGGACA TCAAGCTGGC CCTGGACATG GAGATCCACG CCTACCGCAA GCTCTTGGAG 
GGCGAGGAGG AGAGGCTACG CCTGTCCCCC AGCCCTACCT CGCAGCGCAG CCGTGGCCGT 
GCTTCCTCTC ACTCATCCCA GACACAGGGT GGGGGCAGCG TCACCAAAAA GCGCAAACTG 
GAGTCCACTG AGAGCCGCAG CAGCTTCTCA CAGCACGCAC GCACTAGCGG GCGCGTGGCC 
GTGGAGGAGG TGGATGAGGA GGGCAAGTTT GTCCGGCTGC GCAACAAGTC CAATGAGGAC 
CAGTCCATGG GCAATTGGCA GATCAAGCGC CAGAATGGAG ATGATCCCTT GCTGACTTAC 
CGGTTCCCAC CAAAGTTCAC CCTGAAGGCT GGGCAGGTGG TGACGATCTG GGCTGCAGGA 
GCTGGGGCCA CCCACAGCCC CCCTACCGAC CTGGTGTGGA AGGCACAGAA CACCTGGGGC 
TGCGGGAACA GCCTGCGTAC GGCTCTCATC AACTCCACTG GGGAAGAAGT GGCCATGCGC 
AAGCTGGTGC GCTCAGTGAC TGTGGTTGAG GACGACGAGG ATGAGGATGG AGATGACCTG 
CTCCATCACC ACCACGTGAG TGGTAGCCGC CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( XM_011509533.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507835.1 Homo sapiens lamin A/C (LMNA), transcript variant X1, mRNA.

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CloneID	OHu58735
Clone ID Related Accession (Same CDS sequence)	XM_011509533.1
Accession Version	XM_011509533.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1659bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lamin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAACT CTGAGGGCTG CAATACCAAG AAGGAGGGTG ACCTGATAGC TGCTCAGGCT 
CGGCTGAAGG ACCTGGAGGC TCTGCTGAAC TCCAAGGAGG CCGCACTGAG CACTGCTCTC 
AGTGAGAAGC GCACGCTGGA GGGCGAGCTG CATGATCTGC GGGGCCAGGT GGCCAAGCTT 
GAGGCAGCCC TAGGTGAGGC CAAGAAGCAA CTTCAGGATG AGATGCTGCG GCGGGTGGAT 
GCTGAGAACA GGCTGCAGAC CATGAAGGAG GAACTGGACT TCCAGAAGAA CATCTACAGT 
GAGGAGCTGC GTGAGACCAA GCGCCGTCAT GAGACCCGAC TGGTGGAGAT TGACAATGGG 
AAGCAGCGTG AGTTTGAGAG CCGGCTGGCG GATGCGCTGC AGGAACTGCG GGCCCAGCAT 
GAGGACCAGG TGGAGCAGTA TAAGAAGGAG CTGGAGAAGA CTTATTCTGC CAAGCTGGAC 
AATGCCAGGC AGTCTGCTGA GAGGAACAGC AACCTGGTGG GGGCTGCCCA CGAGGAGCTG 
CAGCAGTCGC GCATCCGCAT CGACAGCCTC TCTGCCCAGC TCAGCCAGCT CCAGAAGCAG 
CTGGCAGCCA AGGAGGCGAA GCTTCGAGAC CTGGAGGACT CACTGGCCCG TGAGCGGGAC 
ACCAGCCGGC GGCTGCTGGC GGAAAAGGAG CGGGAGATGG CCGAGATGCG GGCAAGGATG 
CAGCAGCAGC TGGACGAGTA CCAGGAGCTT CTGGACATCA AGCTGGCCCT GGACATGGAG 
ATCCACGCCT ACCGCAAGCT CTTGGAGGGC GAGGAGGAGA GGCTACGCCT GTCCCCCAGC 
CCTACCTCGC AGCGCAGCCG TGGCCGTGCT TCCTCTCACT CATCCCAGAC ACAGGGTGGG 
GGCAGCGTCA CCAAAAAGCG CAAACTGGAG TCCACTGAGA GCCGCAGCAG CTTCTCACAG 
CACGCACGCA CTAGCGGGCG CGTGGCCGTG GAGGAGGTGG ATGAGGAGGG CAAGTTTGTC 
CGGCTGCGCA ACAAGTCCAA TGAGGACCAG TCCATGGGCA ATTGGCAGAT CAAGCGCCAG 
AATGGAGATG ATCCCTTGCT GACTTACCGG TTCCCACCAA AGTTCACCCT GAAGGCTGGG 
CAGGTGGTGA CGATCTGGGC TGCAGGAGCT GGGGCCACCC ACAGCCCCCC TACCGACCTG 
GTGTGGAAGG CACAGAACAC CTGGGGCTGC GGGAACAGCC TGCGTACGGC TCTCATCAAC 
TCCACTGGGG AAGAAGTGGC CATGCGCAAG CTGGTGCGCT CAGTGACTGT GGTTGAGGAC 
GACGAGGATG AGGATGGAGA TGACCTGCTC CATCACCACC ACGGCTCCCA CTGCAGCAGC 
TCGGGGGACC CCGCTGAGTA CAACCTGCGC TCGCGCACCG TGCTGTGCGG GACCTGCGGG 
CAGCCTGCCG ACAAGGCATC TGCCAGCGGC TCAGGAGCCC AGGTGGGCGG ACCCATCTCC 
TCTGGCTCTT CTGCCTCCAG TGTCACGGTC ACTCGCAGCT ACCGCAGTGT GGGGGGCAGT 
GGGGGTGGCA GCTTCGGGGA CAATCTGGTC ACCCGCTCCT ACCTCCTGGG CAACTCCAGC 
CCCCGAACCC AGAGCCCCCA GAACTGCAGC ATCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507835.1
CDS	83..1741
Translation	MGNSEGCNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM

Target ORF information:

RefSeq Version	XM_011509533.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509533.1

ORF Insert Sequence:

ATGGGGAACT CTGAGGGCTG CAATACCAAG AAGGAGGGTG ACCTGATAGC TGCTCAGGCT 
CGGCTGAAGG ACCTGGAGGC TCTGCTGAAC TCCAAGGAGG CCGCACTGAG CACTGCTCTC 
AGTGAGAAGC GCACGCTGGA GGGCGAGCTG CATGATCTGC GGGGCCAGGT GGCCAAGCTT 
GAGGCAGCCC TAGGTGAGGC CAAGAAGCAA CTTCAGGATG AGATGCTGCG GCGGGTGGAT 
GCTGAGAACA GGCTGCAGAC CATGAAGGAG GAACTGGACT TCCAGAAGAA CATCTACAGT 
GAGGAGCTGC GTGAGACCAA GCGCCGTCAT GAGACCCGAC TGGTGGAGAT TGACAATGGG 
AAGCAGCGTG AGTTTGAGAG CCGGCTGGCG GATGCGCTGC AGGAACTGCG GGCCCAGCAT 
GAGGACCAGG TGGAGCAGTA TAAGAAGGAG CTGGAGAAGA CTTATTCTGC CAAGCTGGAC 
AATGCCAGGC AGTCTGCTGA GAGGAACAGC AACCTGGTGG GGGCTGCCCA CGAGGAGCTG 
CAGCAGTCGC GCATCCGCAT CGACAGCCTC TCTGCCCAGC TCAGCCAGCT CCAGAAGCAG 
CTGGCAGCCA AGGAGGCGAA GCTTCGAGAC CTGGAGGACT CACTGGCCCG TGAGCGGGAC 
ACCAGCCGGC GGCTGCTGGC GGAAAAGGAG CGGGAGATGG CCGAGATGCG GGCAAGGATG 
CAGCAGCAGC TGGACGAGTA CCAGGAGCTT CTGGACATCA AGCTGGCCCT GGACATGGAG 
ATCCACGCCT ACCGCAAGCT CTTGGAGGGC GAGGAGGAGA GGCTACGCCT GTCCCCCAGC 
CCTACCTCGC AGCGCAGCCG TGGCCGTGCT TCCTCTCACT CATCCCAGAC ACAGGGTGGG 
GGCAGCGTCA CCAAAAAGCG CAAACTGGAG TCCACTGAGA GCCGCAGCAG CTTCTCACAG 
CACGCACGCA CTAGCGGGCG CGTGGCCGTG GAGGAGGTGG ATGAGGAGGG CAAGTTTGTC 
CGGCTGCGCA ACAAGTCCAA TGAGGACCAG TCCATGGGCA ATTGGCAGAT CAAGCGCCAG 
AATGGAGATG ATCCCTTGCT GACTTACCGG TTCCCACCAA AGTTCACCCT GAAGGCTGGG 
CAGGTGGTGA CGATCTGGGC TGCAGGAGCT GGGGCCACCC ACAGCCCCCC TACCGACCTG 
GTGTGGAAGG CACAGAACAC CTGGGGCTGC GGGAACAGCC TGCGTACGGC TCTCATCAAC 
TCCACTGGGG AAGAAGTGGC CATGCGCAAG CTGGTGCGCT CAGTGACTGT GGTTGAGGAC 
GACGAGGATG AGGATGGAGA TGACCTGCTC CATCACCACC ACGGCTCCCA CTGCAGCAGC 
TCGGGGGACC CCGCTGAGTA CAACCTGCGC TCGCGCACCG TGCTGTGCGG GACCTGCGGG 
CAGCCTGCCG ACAAGGCATC TGCCAGCGGC TCAGGAGCCC AGGTGGGCGG ACCCATCTCC 
TCTGGCTCTT CTGCCTCCAG TGTCACGGTC ACTCGCAGCT ACCGCAGTGT GGGGGGCAGT 
GGGGGTGGCA GCTTCGGGGA CAATCTGGTC ACCCGCTCCT ACCTCCTGGG CAACTCCAGC 
CCCCGAACCC AGAGCCCCCA GAACTGCAGC ATCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( XM_011509534.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507836.1 Homo sapiens lamin A/C (LMNA), transcript variant X2, mRNA.

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CloneID	OHu58736
Clone ID Related Accession (Same CDS sequence)	XM_011509534.1 , XM_011509534.2
Accession Version	XM_011509534.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	lamin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGACCCG ACTGGTGGAG ATTGACAATG GGAAGCAGCG TGAGTTTGAG AGCCGGCTGG 
CGGATGCGCT GCAGGAACTG CGGGCCCAGC ATGAGGACCA GGTGGAGCAG TATAAGAAGG 
AGCTGGAGAA GACTTATTCT GCCAAGCTGG ACAATGCCAG GCAGTCTGCT GAGAGGAACA 
GCAACCTGGT GGGGGCTGCC CACGAGGAGC TGCAGCAGTC GCGCATCCGC ATCGACAGCC 
TCTCTGCCCA GCTCAGCCAG CTCCAGAAGC AGGGCCCTTG GGAGCTCACC AAACCCTCCC 
ACCCCCCTTC AGCTGGCAGC CAAGGAGGCG AAGCTTCGAG ACCTGGAGGA CTCACTGGCC 
CGTGAGCGGG ACACCAGCCG GCGGCTGCTG GCGGAAAAGG AGCGGGAGAT GGCCGAGATG 
CGGGCAAGGA TGCAGCAGCA GCTGGACGAG TACCAGGAGC TTCTGGACAT CAAGCTGGCC 
CTGGACATGG AGATCCACGC CTACCGCAAG CTCTTGGAGG GCGAGGAGGA GAGGCTACGC 
CTGTCCCCCA GCCCTACCTC GCAGCGCAGC CGTGGCCGTG CTTCCTCTCA CTCATCCCAG 
ACACAGGGTG GGGGCAGCGT CACCAAAAAG CGCAAACTGG AGTCCACTGA GAGCCGCAGC 
AGCTTCTCAC AGCACGCACG CACTAGCGGG CGCGTGGCCG TGGAGGAGGT GGATGAGGAG 
GGCAAGTTTG TCCGGCTGCG CAACAAGTCC AATGAGGACC AGTCCATGGG CAATTGGCAG 
ATCAAGCGCC AGAATGGAGA TGATCCCTTG CTGACTTACC GGTTCCCACC AAAGTTCACC 
CTGAAGGCTG GGCAGGTGGT GACGATCTGG GCTGCAGGAG CTGGGGCCAC CCACAGCCCC 
CCTACCGACC TGGTGTGGAA GGCACAGAAC ACCTGGGGCT GCGGGAACAG CCTGCGTACG 
GCTCTCATCA ACTCCACTGG GGAAGAAGTG GCCATGCGCA AGCTGGTGCG CTCAGTGACT 
GTGGTTGAGG ACGACGAGGA TGAGGATGGA GATGACCTGC TCCATCACCA CCACGGCTCC 
CACTGCAGCA GCTCGGGGGA CCCCGCTGAG TACAACCTGC GCTCGCGCAC CGTGCTGTGC 
GGGACCTGCG GGCAGCCTGC CGACAAGGCA TCTGCCAGCG GCTCAGGAGC CCAGGTGGGC 
GGACCCATCT CCTCTGGCTC TTCTGCCTCC AGTGTCACGG TCACTCGCAG CTACCGCAGT 
GTGGGGGGCA GTGGGGGTGG CAGCTTCGGG GACAATCTGG TCACCCGCTC CTACCTCCTG 
GGCAACTCCA GCCCCCGAAC CCAGAGCCCC CAGAACTGCA GCATCATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507836.1
CDS	309..1679
Translation	MRPDWWRLTMGSSVSLRAGWRMRCRNCGPSMRTRWSSIRRSWRRLILPSWTMPGSLLRGTATWWGLPTRSCSSRASASTASLPSSASSRSRALGSSPNPPTPLQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM

Target ORF information:

RefSeq Version	XM_011509534.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509534.1

ORF Insert Sequence:

ATGAGACCCG ACTGGTGGAG ATTGACAATG GGAAGCAGCG TGAGTTTGAG AGCCGGCTGG 
CGGATGCGCT GCAGGAACTG CGGGCCCAGC ATGAGGACCA GGTGGAGCAG TATAAGAAGG 
AGCTGGAGAA GACTTATTCT GCCAAGCTGG ACAATGCCAG GCAGTCTGCT GAGAGGAACA 
GCAACCTGGT GGGGGCTGCC CACGAGGAGC TGCAGCAGTC GCGCATCCGC ATCGACAGCC 
TCTCTGCCCA GCTCAGCCAG CTCCAGAAGC AGGGCCCTTG GGAGCTCACC AAACCCTCCC 
ACCCCCCTTC AGCTGGCAGC CAAGGAGGCG AAGCTTCGAG ACCTGGAGGA CTCACTGGCC 
CGTGAGCGGG ACACCAGCCG GCGGCTGCTG GCGGAAAAGG AGCGGGAGAT GGCCGAGATG 
CGGGCAAGGA TGCAGCAGCA GCTGGACGAG TACCAGGAGC TTCTGGACAT CAAGCTGGCC 
CTGGACATGG AGATCCACGC CTACCGCAAG CTCTTGGAGG GCGAGGAGGA GAGGCTACGC 
CTGTCCCCCA GCCCTACCTC GCAGCGCAGC CGTGGCCGTG CTTCCTCTCA CTCATCCCAG 
ACACAGGGTG GGGGCAGCGT CACCAAAAAG CGCAAACTGG AGTCCACTGA GAGCCGCAGC 
AGCTTCTCAC AGCACGCACG CACTAGCGGG CGCGTGGCCG TGGAGGAGGT GGATGAGGAG 
GGCAAGTTTG TCCGGCTGCG CAACAAGTCC AATGAGGACC AGTCCATGGG CAATTGGCAG 
ATCAAGCGCC AGAATGGAGA TGATCCCTTG CTGACTTACC GGTTCCCACC AAAGTTCACC 
CTGAAGGCTG GGCAGGTGGT GACGATCTGG GCTGCAGGAG CTGGGGCCAC CCACAGCCCC 
CCTACCGACC TGGTGTGGAA GGCACAGAAC ACCTGGGGCT GCGGGAACAG CCTGCGTACG 
GCTCTCATCA ACTCCACTGG GGAAGAAGTG GCCATGCGCA AGCTGGTGCG CTCAGTGACT 
GTGGTTGAGG ACGACGAGGA TGAGGATGGA GATGACCTGC TCCATCACCA CCACGGCTCC 
CACTGCAGCA GCTCGGGGGA CCCCGCTGAG TACAACCTGC GCTCGCGCAC CGTGCTGTGC 
GGGACCTGCG GGCAGCCTGC CGACAAGGCA TCTGCCAGCG GCTCAGGAGC CCAGGTGGGC 
GGACCCATCT CCTCTGGCTC TTCTGCCTCC AGTGTCACGG TCACTCGCAG CTACCGCAGT 
GTGGGGGGCA GTGGGGGTGG CAGCTTCGGG GACAATCTGG TCACCCGCTC CTACCTCCTG 
GGCAACTCCA GCCCCCGAAC CCAGAGCCCC CAGAACTGCA GCATCATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LMNA ( XM_011509534.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507836.1 Homo sapiens lamin A/C (LMNA), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu58736
Clone ID Related Accession (Same CDS sequence)	XM_011509534.1 , XM_011509534.2
Accession Version	XM_011509534.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lamin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011509534.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGACCCG ACTGGTGGAG ATTGACAATG GGAAGCAGCG TGAGTTTGAG AGCCGGCTGG 
CGGATGCGCT GCAGGAACTG CGGGCCCAGC ATGAGGACCA GGTGGAGCAG TATAAGAAGG 
AGCTGGAGAA GACTTATTCT GCCAAGCTGG ACAATGCCAG GCAGTCTGCT GAGAGGAACA 
GCAACCTGGT GGGGGCTGCC CACGAGGAGC TGCAGCAGTC GCGCATCCGC ATCGACAGCC 
TCTCTGCCCA GCTCAGCCAG CTCCAGAAGC AGGGCCCTTG GGAGCTCACC AAACCCTCCC 
ACCCCCCTTC AGCTGGCAGC CAAGGAGGCG AAGCTTCGAG ACCTGGAGGA CTCACTGGCC 
CGTGAGCGGG ACACCAGCCG GCGGCTGCTG GCGGAAAAGG AGCGGGAGAT GGCCGAGATG 
CGGGCAAGGA TGCAGCAGCA GCTGGACGAG TACCAGGAGC TTCTGGACAT CAAGCTGGCC 
CTGGACATGG AGATCCACGC CTACCGCAAG CTCTTGGAGG GCGAGGAGGA GAGGCTACGC 
CTGTCCCCCA GCCCTACCTC GCAGCGCAGC CGTGGCCGTG CTTCCTCTCA CTCATCCCAG 
ACACAGGGTG GGGGCAGCGT CACCAAAAAG CGCAAACTGG AGTCCACTGA GAGCCGCAGC 
AGCTTCTCAC AGCACGCACG CACTAGCGGG CGCGTGGCCG TGGAGGAGGT GGATGAGGAG 
GGCAAGTTTG TCCGGCTGCG CAACAAGTCC AATGAGGACC AGTCCATGGG CAATTGGCAG 
ATCAAGCGCC AGAATGGAGA TGATCCCTTG CTGACTTACC GGTTCCCACC AAAGTTCACC 
CTGAAGGCTG GGCAGGTGGT GACGATCTGG GCTGCAGGAG CTGGGGCCAC CCACAGCCCC 
CCTACCGACC TGGTGTGGAA GGCACAGAAC ACCTGGGGCT GCGGGAACAG CCTGCGTACG 
GCTCTCATCA ACTCCACTGG GGAAGAAGTG GCCATGCGCA AGCTGGTGCG CTCAGTGACT 
GTGGTTGAGG ACGACGAGGA TGAGGATGGA GATGACCTGC TCCATCACCA CCACGGCTCC 
CACTGCAGCA GCTCGGGGGA CCCCGCTGAG TACAACCTGC GCTCGCGCAC CGTGCTGTGC 
GGGACCTGCG GGCAGCCTGC CGACAAGGCA TCTGCCAGCG GCTCAGGAGC CCAGGTGGGC 
GGACCCATCT CCTCTGGCTC TTCTGCCTCC AGTGTCACGG TCACTCGCAG CTACCGCAGT 
GTGGGGGGCA GTGGGGGTGG CAGCTTCGGG GACAATCTGG TCACCCGCTC CTACCTCCTG 
GGCAACTCCA GCCCCCGAAC CCAGAGCCCC CAGAACTGCA GCATCATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507836.1
CDS	411..1781
Translation	MRPDWWRLTMGSSVSLRAGWRMRCRNCGPSMRTRWSSIRRSWRRLILPSWTMPGSLLRGTATWWGLPTRSCSSRASASTASLPSSASSRSRALGSSPNPPTPLQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM

Target ORF information:

RefSeq Version	XM_011509534.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lamin A/C (LMNA), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509534.2

ORF Insert Sequence:

ATGAGACCCG ACTGGTGGAG ATTGACAATG GGAAGCAGCG TGAGTTTGAG AGCCGGCTGG 
CGGATGCGCT GCAGGAACTG CGGGCCCAGC ATGAGGACCA GGTGGAGCAG TATAAGAAGG 
AGCTGGAGAA GACTTATTCT GCCAAGCTGG ACAATGCCAG GCAGTCTGCT GAGAGGAACA 
GCAACCTGGT GGGGGCTGCC CACGAGGAGC TGCAGCAGTC GCGCATCCGC ATCGACAGCC 
TCTCTGCCCA GCTCAGCCAG CTCCAGAAGC AGGGCCCTTG GGAGCTCACC AAACCCTCCC 
ACCCCCCTTC AGCTGGCAGC CAAGGAGGCG AAGCTTCGAG ACCTGGAGGA CTCACTGGCC 
CGTGAGCGGG ACACCAGCCG GCGGCTGCTG GCGGAAAAGG AGCGGGAGAT GGCCGAGATG 
CGGGCAAGGA TGCAGCAGCA GCTGGACGAG TACCAGGAGC TTCTGGACAT CAAGCTGGCC 
CTGGACATGG AGATCCACGC CTACCGCAAG CTCTTGGAGG GCGAGGAGGA GAGGCTACGC 
CTGTCCCCCA GCCCTACCTC GCAGCGCAGC CGTGGCCGTG CTTCCTCTCA CTCATCCCAG 
ACACAGGGTG GGGGCAGCGT CACCAAAAAG CGCAAACTGG AGTCCACTGA GAGCCGCAGC 
AGCTTCTCAC AGCACGCACG CACTAGCGGG CGCGTGGCCG TGGAGGAGGT GGATGAGGAG 
GGCAAGTTTG TCCGGCTGCG CAACAAGTCC AATGAGGACC AGTCCATGGG CAATTGGCAG 
ATCAAGCGCC AGAATGGAGA TGATCCCTTG CTGACTTACC GGTTCCCACC AAAGTTCACC 
CTGAAGGCTG GGCAGGTGGT GACGATCTGG GCTGCAGGAG CTGGGGCCAC CCACAGCCCC 
CCTACCGACC TGGTGTGGAA GGCACAGAAC ACCTGGGGCT GCGGGAACAG CCTGCGTACG 
GCTCTCATCA ACTCCACTGG GGAAGAAGTG GCCATGCGCA AGCTGGTGCG CTCAGTGACT 
GTGGTTGAGG ACGACGAGGA TGAGGATGGA GATGACCTGC TCCATCACCA CCACGGCTCC 
CACTGCAGCA GCTCGGGGGA CCCCGCTGAG TACAACCTGC GCTCGCGCAC CGTGCTGTGC 
GGGACCTGCG GGCAGCCTGC CGACAAGGCA TCTGCCAGCG GCTCAGGAGC CCAGGTGGGC 
GGACCCATCT CCTCTGGCTC TTCTGCCTCC AGTGTCACGG TCACTCGCAG CTACCGCAGT 
GTGGGGGGCA GTGGGGGTGG CAGCTTCGGG GACAATCTGG TCACCCGCTC CTACCTCCTG 
GGCAACTCCA GCCCCCGAAC CCAGAGCCCC CAGAACTGCA GCATCATGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	LMNA
Entrez Gene ID	4000
Full Name	lamin A/C
Synonyms	CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,FPLD2,HGPS,IDC,LDP1,LFP,LGMD1B,LMN1,LMNC,LMNL1,MADA,PRO1
General protein information	Preferred Names lamin A/C Names lamin 70 kDa lamin lamin A/C-like 1 mandibuloacral dysplasia type A prelamin-A/C renal carcinoma antigen NY-REN-32
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q22
Summary	The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012].
Disorder MIM:	150330
Disorder Html:	Emery-Dreifuss muscular dystrophy 2, AD, 181350 (3); Cardiomyopathy, dilated, 1A, 115200 (3); Lipodystrophy, familial partial, type 2, 151660 (3); Emery-Dreifuss muscular dystrophy 3, AR, 616516 (3); Charcot-Marie-Tooth disease, type 2B1, 605588 (3); Muscular dystrophy, congenital, 613205 (3); Muscular dystrophy, limb-girdle, type 1B, 159001 (3); Mandibuloacral dysplasia, 248370 (3); Hutchinson-Gilford progeria, 176670 (3); Restrictive dermopathy, lethal, 275210 (3); Heart-hand syndrome, Slovenian type, 610140 (3); Malouf syndrome, 212112 (3)

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008015	XP_317447.4
	LMNA	XP_001113604.2
Danio rerio (zebrafish)	lmna	NP_694503.1
Pan troglodytes (chimpanzee)	LMNA	NP_001092024.1
Canis lupus familiaris (dog)	LMNA	XP_005622768.1
Mus musculus (house mouse)	Lmna	NP_001002011.2
Rattus norvegicus (Norway rat)	Lmna	NP_001002016.1
Xenopus tropicalis (tropical clawed frog)	lmna	NP_001039148.1
Bos taurus (cattle)	LMNA	NP_001029225.1
Homo sapiens (human)	LMNA	NP_733821.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

LMNA cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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