LCP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LCP1
Entrez Gene ID	3936
Full Name	lymphocyte cytosolic protein 1
Synonyms	CP64,HEL-S-37,L-PLASTIN,LC64P,LPL,PLS2
General protein information	Preferred Names lymphocyte cytosolic protein 1 Names plastin-2 L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P) LCP-1 Lymphocyte cytosolic protein-1 (plasmin) bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)) epididymis secretory protein Li 37
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q14.13
Summary	Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008].
Disorder MIM:	153430

mRNA and Protein(s)

mRNA	Protein	Name
NM_002298.5	NP_002289.2	plastin-2
NM_002298.4	NP_002289.2	plastin-2
XM_005266374.2	XP_005266431.1	plastin-2 isoform X1
XM_005266374.1	XP_005266431.1	plastin-2 isoform X1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004071	XP_309626.4
Kluyveromyces lactis	KLLA0F19778g	XP_455968.1
Magnaporthe oryzae (rice blast fungus)	MGG_04478	XP_003710980.1
Arabidopsis thaliana (thale cress)	FIM2	NP_198420.1
Oryza sativa (rice)	Os02g0588300	NP_001047274.1
Homo sapiens (human)	LCP1	NP_002289.2
Pan troglodytes (chimpanzee)	LCP1	XP_001158161.1
Rattus norvegicus (Norway rat)	Lcp1	NP_001012044.1
Gallus gallus (chicken)	LCP1	NP_001008440.1
Drosophila melanogaster (fruit fly)	Fim	NP_523385.1
Caenorhabditis elegans (roundworm)	plst-1	NP_500061.4
Saccharomyces cerevisiae (baker's yeast)	SAC6	NP_010414.3
Schizosaccharomyces pombe (fission yeast)	fim1	NP_596289.1
	LCP1	XP_002800787.1
Canis lupus familiaris (dog)	LCP1	XP_005633943.1
Mus musculus (house mouse)	Lcp1	NP_032905.2
Danio rerio (zebrafish)	lcp1	NP_571395.1
Arabidopsis thaliana (thale cress)	AT2G04750	NP_178552.1
Xenopus tropicalis (tropical clawed frog)	lcp1	NP_001015721.1
Bos taurus (cattle)	LCP1	NP_001029892.1
Eremothecium gossypii	AGOS_AGR069C	NP_986734.2
Neurospora crassa	NCU03992	XP_956577.2

Gene Ontology
Bibliography

Related articles in PubMed

Angiotensin II regulates phosphorylation of actin-associated proteins in human podocytes.
Schenk LK, M?ller-Kerutt A, Klosowski R, Wolters D, Schaffner-Reckinger E, Weide T, Pavenst?dt H, Vollenbr?ker B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(11)5019-5035(2017 Nov)

AP4 modulated by the PI3K/AKT pathway promotes prostate cancer proliferation and metastasis of prostate cancer via upregulating L-plastin.
Chen C, Cai Q, He W, Lam TB, Lin J, Zhao Y, Chen X, Gu P, Huang H, Xue M, Liu H, Su F, Huang J, Zheng J, Lin T
Cell death & disease8(10)e3060(2017 Oct)

The Roles of Actin-Binding Domains 1 and 2 in the Calcium-Dependent Regulation of Actin Filament Bundling by Human Plastins.
Schwebach CL, Agrawal R, Lindert S, Kudryashova E, Kudryashov DS
Journal of molecular biology429(16)2490-2508(2017 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

AngII-dependent phosphorylation of LCP1 in cultured podocytes was mediated by the kinases ERK, p90 ribosomal S6 kinase, PKA, or PKC. LCP1 phosphorylation increased filopodia formation.
Title: Angiotensin II regulates phosphorylation of actin-associated proteins in human podocytes.

In this study, the authors found that the actin filament bundling abilities of PLS1 and PLS2 were similarly sensitive to Ca(2+) (pCa50 ~6.4), whereas PLS3 was less sensitive (pCa50 ~5.9).
Title: The Roles of Actin-Binding Domains 1 and 2 in the Calcium-Dependent Regulation of Actin Filament Bundling by Human Plastins.

The findings support a mechanism in which miR-375 suppresses RUNX1 levels, resulting in reduced vimentin and L-plastin expression. Knockdown of RUNX1, L-plastin, and vimentin resulted in significant reductions in cell invasion in vitro, indicating the functional significance of miR-375 regulation of specific proteins involved in head and neck squamous cell carcinoma (HNSCC) invasion.
Title: miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin.

L-plastin regulates the stability of the immune synapse of naive and effector T-cells. (Review)
Title: L-plastin regulates the stability of the immune synapse of naive and effector T-cells.

elevated L-plastin expression promotes elongation and reduces protrusion density in cells with relatively lower L-plastin than fascin levels.
Title: Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia.

The following LCP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LCP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17576	NM_002298.5 Latest version!	Homo sapiens lymphocyte cytosolic protein 1 (LCP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu17576	XM_005266374.2 Latest version!	Homo sapiens lymphocyte cytosolic protein 1 (LCP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
View Old Accession Versions >>
OHu17576	NM_002298.4	Homo sapiens lymphocyte cytosolic protein 1 (LCP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu17576	XM_005266374.1	Homo sapiens lymphocyte cytosolic protein 1 (LCP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LCP1 ( NM_002298.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002289.2 Homo sapiens lymphocyte cytosolic protein 1 (LCP1), mRNA.

Price & Availability↑

CloneID	OHu17576
Clone ID Related Accession (Same CDS sequence)	NM_002298.5 , NM_002298.4 , XM_005266374.2 , XM_005266374.1
Accession Version	NM_002298.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1884bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	plastin-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB156931.1, J02923.1, DA820090.1, BC007673.1, BF893502.1 and AY960627.3. On Nov 22, 2018 this sequence version replaced NM_002298.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC007673.1, SRR1803612.207835.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000323076.7/ ENSP00000315757.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCAGAG GATCAGTGTC CGATGAGGAA ATGATGGAGC TCAGAGAAGC TTTTGCCAAA 
GTTGATACTG ATGGCAATGG ATACATCAGC TTCAATGAGT TGAATGACTT GTTCAAGGCT 
GCTTGCTTGC CTTTGCCTGG GTATAGAGTA CGAGAAATTA CAGAAAACCT GATGGCTACA 
GGTGATCTGG ACCAAGATGG AAGGATCAGC TTTGATGAGT TTATCAAGAT TTTCCATGGC 
CTAAAAAGCA CAGATGTTGC CAAGACCTTT AGAAAAGCAA TCAATAAGAA GGAAGGGATT 
TGTGCAATCG GTGGTACTTC AGAGCAGTCT AGCGTTGGCA CCCAACACTC CTATTCAGAG 
GAAGAAAAGT ATGCCTTTGT CAACTGGATA AACAAAGCCC TGGAAAATGA TCCTGATTGT 
CGGCATGTCA TCCCAATGAA CCCAAACACG AATGATCTCT TTAATGCTGT TGGAGATGGC 
ATTGTCCTTT GTAAAATGAT CAACCTGTCA GTGCCAGACA CAATTGATGA AAGAACAATC 
AACAAAAAGA AGCTAACCCC TTTCACCATT CAGGAAAATC TGAACTTGGC TCTGAACTCT 
GCCTCAGCCA TCGGGTGCCA TGTGGTCAAC ATAGGGGCTG AGGACCTGAA GGAGGGGAAG 
CCTTATCTGG TCCTGGGACT TCTGTGGCAA GTCATCAAGA TTGGGTTGTT TGCTGACATT 
GAACTCAGCA GAAATGAAGC TCTGATTGCT CTTTTGAGAG AAGGTGAGAG CCTGGAGGAT 
TTGATGAAAC TCTCCCCTGA AGAGCTCTTG CTGAGGTGGG CTAATTACCA CCTGGAAAAT 
GCAGGCTGCA ACAAAATTGG CAACTTCAGT ACTGACATCA AGGACTCAAA AGCTTATTAC 
CACCTGCTTG AGCAGGTGGC TCCAAAAGGA GATGAAGAAG GTGTTCCTGC TGTTGTTATT 
GACATGTCAG GACTGCGGGA GAAGGATGAC ATCCAGAGGG CAGAATGCAT GCTGCAGCAG 
GCGGAGAGGC TGGGCTGCCG GCAGTTTGTC ACAGCCACAG ATGTTGTCCG AGGGAACCCC 
AAGTTGAACT TGGCTTTTAT TGCCAACCTC TTTAACAGAT ACCCTGCCCT GCACAAACCA 
GAGAACCAGG ACATTGACTG GGGGGCTCTT GAAGGTGAGA CGAGAGAAGA GCGGACATTT 
AGGAACTGGA TGAACTCCCT GGGTGTTAAC CCTCGAGTCA ATCATTTGTA CAGTGACTTA 
TCAGATGCCC TGGTCATCTT CCAGCTCTAT GAAAAGATCA AAGTTCCTGT TGACTGGAAC 
AGAGTAAACA AACCGCCATA CCCCAAACTG GGAGGCAATA TGAAGAAGCT TGAGAATTGT 
AACTACGCGG TAGAATTGGG GAAGAATCAA GCGAAGTTCT CCCTGGTTGG CATCGGTGGA 
CAAGATCTCA ATGAAGGAAA CCGCACTCTC ACACTGGCCT TGATTTGGCA GCTAATGAGA 
AGGTATACAC TGAATATCCT CGAAGAAATT GGTGGTGGCC AGAAGGTCAA TGATGACATT 
ATTGTCAACT GGGTGAATGA AACATTGAGG GAAGCAAAGA AAAGTTCATC CATCTCTAGT 
TTCAAGGACC CGAAGATTAG TACAAGTCTG CCTGTTCTGG ACCTCATCGA TGCCATCCAA 
CCAGGTTCCA TTAACTATGA CCTTCTGAAG ACAGAAAATC TGAATGATGA TGAGAAACTC 
AACAATGCAA AATATGCCAT CTCTATGGCC CGAAAAATTG GAGCAAGAGT GTATGCCCTG 
CCAGAAGACC TGGTTGAAGT GAACCCCAAA ATGGTCATGA CCGTGTTTGC CTGCCTCATG 
GGGAAAGGAA TGAAGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002289.2
CDS	92..1975
Translation	MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV

Target ORF information:

RefSeq Version	NM_002298.5
Organism	Homo sapiens(human)
Definition	Homo sapiens lymphocyte cytosolic protein 1 (LCP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002298.5

ORF Insert Sequence:

ATGGCCAGAG GATCAGTGTC CGATGAGGAA ATGATGGAGC TCAGAGAAGC TTTTGCCAAA 
GTTGATACTG ATGGCAATGG ATACATCAGC TTCAATGAGT TGAATGACTT GTTCAAGGCT 
GCTTGCTTGC CTTTGCCTGG GTATAGAGTA CGAGAAATTA CAGAAAACCT GATGGCTACA 
GGTGATCTGG ACCAAGATGG AAGGATCAGC TTTGATGAGT TTATCAAGAT TTTCCATGGC 
CTAAAAAGCA CAGATGTTGC CAAGACCTTT AGAAAAGCAA TCAATAAGAA GGAAGGGATT 
TGTGCAATCG GTGGTACTTC AGAGCAGTCT AGCGTTGGCA CCCAACACTC CTATTCAGAG 
GAAGAAAAGT ATGCCTTTGT CAACTGGATA AACAAAGCCC TGGAAAATGA TCCTGATTGT 
CGGCATGTCA TCCCAATGAA CCCAAACACG AATGATCTCT TTAATGCTGT TGGAGATGGC 
ATTGTCCTTT GTAAAATGAT CAACCTGTCA GTGCCAGACA CAATTGATGA AAGAACAATC 
AACAAAAAGA AGCTAACCCC TTTCACCATT CAGGAAAATC TGAACTTGGC TCTGAACTCT 
GCCTCAGCCA TCGGGTGCCA TGTGGTCAAC ATAGGGGCTG AGGACCTGAA GGAGGGGAAG 
CCTTATCTGG TCCTGGGACT TCTGTGGCAA GTCATCAAGA TTGGGTTGTT TGCTGACATT 
GAACTCAGCA GAAATGAAGC TCTGATTGCT CTTTTGAGAG AAGGTGAGAG CCTGGAGGAT 
TTGATGAAAC TCTCCCCTGA AGAGCTCTTG CTGAGGTGGG CTAATTACCA CCTGGAAAAT 
GCAGGCTGCA ACAAAATTGG CAACTTCAGT ACTGACATCA AGGACTCAAA AGCTTATTAC 
CACCTGCTTG AGCAGGTGGC TCCAAAAGGA GATGAAGAAG GTGTTCCTGC TGTTGTTATT 
GACATGTCAG GACTGCGGGA GAAGGATGAC ATCCAGAGGG CAGAATGCAT GCTGCAGCAG 
GCGGAGAGGC TGGGCTGCCG GCAGTTTGTC ACAGCCACAG ATGTTGTCCG AGGGAACCCC 
AAGTTGAACT TGGCTTTTAT TGCCAACCTC TTTAACAGAT ACCCTGCCCT GCACAAACCA 
GAGAACCAGG ACATTGACTG GGGGGCTCTT GAAGGTGAGA CGAGAGAAGA GCGGACATTT 
AGGAACTGGA TGAACTCCCT GGGTGTTAAC CCTCGAGTCA ATCATTTGTA CAGTGACTTA 
TCAGATGCCC TGGTCATCTT CCAGCTCTAT GAAAAGATCA AAGTTCCTGT TGACTGGAAC 
AGAGTAAACA AACCGCCATA CCCCAAACTG GGAGGCAATA TGAAGAAGCT TGAGAATTGT 
AACTACGCGG TAGAATTGGG GAAGAATCAA GCGAAGTTCT CCCTGGTTGG CATCGGTGGA 
CAAGATCTCA ATGAAGGAAA CCGCACTCTC ACACTGGCCT TGATTTGGCA GCTAATGAGA 
AGGTATACAC TGAATATCCT CGAAGAAATT GGTGGTGGCC AGAAGGTCAA TGATGACATT 
ATTGTCAACT GGGTGAATGA AACATTGAGG GAAGCAAAGA AAAGTTCATC CATCTCTAGT 
TTCAAGGACC CGAAGATTAG TACAAGTCTG CCTGTTCTGG ACCTCATCGA TGCCATCCAA 
CCAGGTTCCA TTAACTATGA CCTTCTGAAG ACAGAAAATC TGAATGATGA TGAGAAACTC 
AACAATGCAA AATATGCCAT CTCTATGGCC CGAAAAATTG GAGCAAGAGT GTATGCCCTG 
CCAGAAGACC TGGTTGAAGT GAACCCCAAA ATGGTCATGA CCGTGTTTGC CTGCCTCATG 
GGGAAAGGAA TGAAGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCP1 ( NM_002298.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002289.2 Homo sapiens lymphocyte cytosolic protein 1 (LCP1), mRNA.

Price & Availability↑

CloneID	OHu17576
Clone ID Related Accession (Same CDS sequence)	NM_002298.5 , NM_002298.4 , XM_005266374.2 , XM_005266374.1
Accession Version	NM_002298.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1884bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	plastin-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB156931.1, J02923.1, DA820090.1, BC007673.1, BF893502.1 and AY960627.3. On Aug 5, 2008 this sequence version replaced NM_002298.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.177749.1, SRR1803612.207835.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCCAGAG GATCAGTGTC CGATGAGGAA ATGATGGAGC TCAGAGAAGC TTTTGCCAAA 
GTTGATACTG ATGGCAATGG ATACATCAGC TTCAATGAGT TGAATGACTT GTTCAAGGCT 
GCTTGCTTGC CTTTGCCTGG GTATAGAGTA CGAGAAATTA CAGAAAACCT GATGGCTACA 
GGTGATCTGG ACCAAGATGG AAGGATCAGC TTTGATGAGT TTATCAAGAT TTTCCATGGC 
CTAAAAAGCA CAGATGTTGC CAAGACCTTT AGAAAAGCAA TCAATAAGAA GGAAGGGATT 
TGTGCAATCG GTGGTACTTC AGAGCAGTCT AGCGTTGGCA CCCAACACTC CTATTCAGAG 
GAAGAAAAGT ATGCCTTTGT CAACTGGATA AACAAAGCCC TGGAAAATGA TCCTGATTGT 
CGGCATGTCA TCCCAATGAA CCCAAACACG AATGATCTCT TTAATGCTGT TGGAGATGGC 
ATTGTCCTTT GTAAAATGAT CAACCTGTCA GTGCCAGACA CAATTGATGA AAGAACAATC 
AACAAAAAGA AGCTAACCCC TTTCACCATT CAGGAAAATC TGAACTTGGC TCTGAACTCT 
GCCTCAGCCA TCGGGTGCCA TGTGGTCAAC ATAGGGGCTG AGGACCTGAA GGAGGGGAAG 
CCTTATCTGG TCCTGGGACT TCTGTGGCAA GTCATCAAGA TTGGGTTGTT TGCTGACATT 
GAACTCAGCA GAAATGAAGC TCTGATTGCT CTTTTGAGAG AAGGTGAGAG CCTGGAGGAT 
TTGATGAAAC TCTCCCCTGA AGAGCTCTTG CTGAGGTGGG CTAATTACCA CCTGGAAAAT 
GCAGGCTGCA ACAAAATTGG CAACTTCAGT ACTGACATCA AGGACTCAAA AGCTTATTAC 
CACCTGCTTG AGCAGGTGGC TCCAAAAGGA GATGAAGAAG GTGTTCCTGC TGTTGTTATT 
GACATGTCAG GACTGCGGGA GAAGGATGAC ATCCAGAGGG CAGAATGCAT GCTGCAGCAG 
GCGGAGAGGC TGGGCTGCCG GCAGTTTGTC ACAGCCACAG ATGTTGTCCG AGGGAACCCC 
AAGTTGAACT TGGCTTTTAT TGCCAACCTC TTTAACAGAT ACCCTGCCCT GCACAAACCA 
GAGAACCAGG ACATTGACTG GGGGGCTCTT GAAGGTGAGA CGAGAGAAGA GCGGACATTT 
AGGAACTGGA TGAACTCCCT GGGTGTTAAC CCTCGAGTCA ATCATTTGTA CAGTGACTTA 
TCAGATGCCC TGGTCATCTT CCAGCTCTAT GAAAAGATCA AAGTTCCTGT TGACTGGAAC 
AGAGTAAACA AACCGCCATA CCCCAAACTG GGAGGCAATA TGAAGAAGCT TGAGAATTGT 
AACTACGCGG TAGAATTGGG GAAGAATCAA GCGAAGTTCT CCCTGGTTGG CATCGGTGGA 
CAAGATCTCA ATGAAGGAAA CCGCACTCTC ACACTGGCCT TGATTTGGCA GCTAATGAGA 
AGGTATACAC TGAATATCCT CGAAGAAATT GGTGGTGGCC AGAAGGTCAA TGATGACATT 
ATTGTCAACT GGGTGAATGA AACATTGAGG GAAGCAAAGA AAAGTTCATC CATCTCTAGT 
TTCAAGGACC CGAAGATTAG TACAAGTCTG CCTGTTCTGG ACCTCATCGA TGCCATCCAA 
CCAGGTTCCA TTAACTATGA CCTTCTGAAG ACAGAAAATC TGAATGATGA TGAGAAACTC 
AACAATGCAA AATATGCCAT CTCTATGGCC CGAAAAATTG GAGCAAGAGT GTATGCCCTG 
CCAGAAGACC TGGTTGAAGT GAACCCCAAA ATGGTCATGA CCGTGTTTGC CTGCCTCATG 
GGGAAAGGAA TGAAGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002289.2
CDS	239..2122
Translation	MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV

Target ORF information:

RefSeq Version	NM_002298.4
Organism	Homo sapiens(human)
Definition	Homo sapiens lymphocyte cytosolic protein 1 (LCP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002298.4

ORF Insert Sequence:

ATGGCCAGAG GATCAGTGTC CGATGAGGAA ATGATGGAGC TCAGAGAAGC TTTTGCCAAA 
GTTGATACTG ATGGCAATGG ATACATCAGC TTCAATGAGT TGAATGACTT GTTCAAGGCT 
GCTTGCTTGC CTTTGCCTGG GTATAGAGTA CGAGAAATTA CAGAAAACCT GATGGCTACA 
GGTGATCTGG ACCAAGATGG AAGGATCAGC TTTGATGAGT TTATCAAGAT TTTCCATGGC 
CTAAAAAGCA CAGATGTTGC CAAGACCTTT AGAAAAGCAA TCAATAAGAA GGAAGGGATT 
TGTGCAATCG GTGGTACTTC AGAGCAGTCT AGCGTTGGCA CCCAACACTC CTATTCAGAG 
GAAGAAAAGT ATGCCTTTGT CAACTGGATA AACAAAGCCC TGGAAAATGA TCCTGATTGT 
CGGCATGTCA TCCCAATGAA CCCAAACACG AATGATCTCT TTAATGCTGT TGGAGATGGC 
ATTGTCCTTT GTAAAATGAT CAACCTGTCA GTGCCAGACA CAATTGATGA AAGAACAATC 
AACAAAAAGA AGCTAACCCC TTTCACCATT CAGGAAAATC TGAACTTGGC TCTGAACTCT 
GCCTCAGCCA TCGGGTGCCA TGTGGTCAAC ATAGGGGCTG AGGACCTGAA GGAGGGGAAG 
CCTTATCTGG TCCTGGGACT TCTGTGGCAA GTCATCAAGA TTGGGTTGTT TGCTGACATT 
GAACTCAGCA GAAATGAAGC TCTGATTGCT CTTTTGAGAG AAGGTGAGAG CCTGGAGGAT 
TTGATGAAAC TCTCCCCTGA AGAGCTCTTG CTGAGGTGGG CTAATTACCA CCTGGAAAAT 
GCAGGCTGCA ACAAAATTGG CAACTTCAGT ACTGACATCA AGGACTCAAA AGCTTATTAC 
CACCTGCTTG AGCAGGTGGC TCCAAAAGGA GATGAAGAAG GTGTTCCTGC TGTTGTTATT 
GACATGTCAG GACTGCGGGA GAAGGATGAC ATCCAGAGGG CAGAATGCAT GCTGCAGCAG 
GCGGAGAGGC TGGGCTGCCG GCAGTTTGTC ACAGCCACAG ATGTTGTCCG AGGGAACCCC 
AAGTTGAACT TGGCTTTTAT TGCCAACCTC TTTAACAGAT ACCCTGCCCT GCACAAACCA 
GAGAACCAGG ACATTGACTG GGGGGCTCTT GAAGGTGAGA CGAGAGAAGA GCGGACATTT 
AGGAACTGGA TGAACTCCCT GGGTGTTAAC CCTCGAGTCA ATCATTTGTA CAGTGACTTA 
TCAGATGCCC TGGTCATCTT CCAGCTCTAT GAAAAGATCA AAGTTCCTGT TGACTGGAAC 
AGAGTAAACA AACCGCCATA CCCCAAACTG GGAGGCAATA TGAAGAAGCT TGAGAATTGT 
AACTACGCGG TAGAATTGGG GAAGAATCAA GCGAAGTTCT CCCTGGTTGG CATCGGTGGA 
CAAGATCTCA ATGAAGGAAA CCGCACTCTC ACACTGGCCT TGATTTGGCA GCTAATGAGA 
AGGTATACAC TGAATATCCT CGAAGAAATT GGTGGTGGCC AGAAGGTCAA TGATGACATT 
ATTGTCAACT GGGTGAATGA AACATTGAGG GAAGCAAAGA AAAGTTCATC CATCTCTAGT 
TTCAAGGACC CGAAGATTAG TACAAGTCTG CCTGTTCTGG ACCTCATCGA TGCCATCCAA 
CCAGGTTCCA TTAACTATGA CCTTCTGAAG ACAGAAAATC TGAATGATGA TGAGAAACTC 
AACAATGCAA AATATGCCAT CTCTATGGCC CGAAAAATTG GAGCAAGAGT GTATGCCCTG 
CCAGAAGACC TGGTTGAAGT GAACCCCAAA ATGGTCATGA CCGTGTTTGC CTGCCTCATG 
GGGAAAGGAA TGAAGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCP1 ( XM_005266374.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005266431.1 Homo sapiens lymphocyte cytosolic protein 1 (LCP1), transcript variant X1, mRNA.

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CloneID	OHu17576
Clone ID Related Accession (Same CDS sequence)	NM_002298.5 , NM_002298.4 , XM_005266374.2 , XM_005266374.1
Accession Version	XM_005266374.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1884bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	plastin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005266374.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAGAG GATCAGTGTC CGATGAGGAA ATGATGGAGC TCAGAGAAGC TTTTGCCAAA 
GTTGATACTG ATGGCAATGG ATACATCAGC TTCAATGAGT TGAATGACTT GTTCAAGGCT 
GCTTGCTTGC CTTTGCCTGG GTATAGAGTA CGAGAAATTA CAGAAAACCT GATGGCTACA 
GGTGATCTGG ACCAAGATGG AAGGATCAGC TTTGATGAGT TTATCAAGAT TTTCCATGGC 
CTAAAAAGCA CAGATGTTGC CAAGACCTTT AGAAAAGCAA TCAATAAGAA GGAAGGGATT 
TGTGCAATCG GTGGTACTTC AGAGCAGTCT AGCGTTGGCA CCCAACACTC CTATTCAGAG 
GAAGAAAAGT ATGCCTTTGT CAACTGGATA AACAAAGCCC TGGAAAATGA TCCTGATTGT 
CGGCATGTCA TCCCAATGAA CCCAAACACG AATGATCTCT TTAATGCTGT TGGAGATGGC 
ATTGTCCTTT GTAAAATGAT CAACCTGTCA GTGCCAGACA CAATTGATGA AAGAACAATC 
AACAAAAAGA AGCTAACCCC TTTCACCATT CAGGAAAATC TGAACTTGGC TCTGAACTCT 
GCCTCAGCCA TCGGGTGCCA TGTGGTCAAC ATAGGGGCTG AGGACCTGAA GGAGGGGAAG 
CCTTATCTGG TCCTGGGACT TCTGTGGCAA GTCATCAAGA TTGGGTTGTT TGCTGACATT 
GAACTCAGCA GAAATGAAGC TCTGATTGCT CTTTTGAGAG AAGGTGAGAG CCTGGAGGAT 
TTGATGAAAC TCTCCCCTGA AGAGCTCTTG CTGAGGTGGG CTAATTACCA CCTGGAAAAT 
GCAGGCTGCA ACAAAATTGG CAACTTCAGT ACTGACATCA AGGACTCAAA AGCTTATTAC 
CACCTGCTTG AGCAGGTGGC TCCAAAAGGA GATGAAGAAG GTGTTCCTGC TGTTGTTATT 
GACATGTCAG GACTGCGGGA GAAGGATGAC ATCCAGAGGG CAGAATGCAT GCTGCAGCAG 
GCGGAGAGGC TGGGCTGCCG GCAGTTTGTC ACAGCCACAG ATGTTGTCCG AGGGAACCCC 
AAGTTGAACT TGGCTTTTAT TGCCAACCTC TTTAACAGAT ACCCTGCCCT GCACAAACCA 
GAGAACCAGG ACATTGACTG GGGGGCTCTT GAAGGTGAGA CGAGAGAAGA GCGGACATTT 
AGGAACTGGA TGAACTCCCT GGGTGTTAAC CCTCGAGTCA ATCATTTGTA CAGTGACTTA 
TCAGATGCCC TGGTCATCTT CCAGCTCTAT GAAAAGATCA AAGTTCCTGT TGACTGGAAC 
AGAGTAAACA AACCGCCATA CCCCAAACTG GGAGGCAATA TGAAGAAGCT TGAGAATTGT 
AACTACGCGG TAGAATTGGG GAAGAATCAA GCGAAGTTCT CCCTGGTTGG CATCGGTGGA 
CAAGATCTCA ATGAAGGAAA CCGCACTCTC ACACTGGCCT TGATTTGGCA GCTAATGAGA 
AGGTATACAC TGAATATCCT CGAAGAAATT GGTGGTGGCC AGAAGGTCAA TGATGACATT 
ATTGTCAACT GGGTGAATGA AACATTGAGG GAAGCAAAGA AAAGTTCATC CATCTCTAGT 
TTCAAGGACC CGAAGATTAG TACAAGTCTG CCTGTTCTGG ACCTCATCGA TGCCATCCAA 
CCAGGTTCCA TTAACTATGA CCTTCTGAAG ACAGAAAATC TGAATGATGA TGAGAAACTC 
AACAATGCAA AATATGCCAT CTCTATGGCC CGAAAAATTG GAGCAAGAGT GTATGCCCTG 
CCAGAAGACC TGGTTGAAGT GAACCCCAAA ATGGTCATGA CCGTGTTTGC CTGCCTCATG 
GGGAAAGGAA TGAAGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005266431.1
CDS	124..2007
Translation	MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV

Target ORF information:

RefSeq Version	XM_005266374.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lymphocyte cytosolic protein 1 (LCP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005266374.2

ORF Insert Sequence:

ATGGCCAGAG GATCAGTGTC CGATGAGGAA ATGATGGAGC TCAGAGAAGC TTTTGCCAAA 
GTTGATACTG ATGGCAATGG ATACATCAGC TTCAATGAGT TGAATGACTT GTTCAAGGCT 
GCTTGCTTGC CTTTGCCTGG GTATAGAGTA CGAGAAATTA CAGAAAACCT GATGGCTACA 
GGTGATCTGG ACCAAGATGG AAGGATCAGC TTTGATGAGT TTATCAAGAT TTTCCATGGC 
CTAAAAAGCA CAGATGTTGC CAAGACCTTT AGAAAAGCAA TCAATAAGAA GGAAGGGATT 
TGTGCAATCG GTGGTACTTC AGAGCAGTCT AGCGTTGGCA CCCAACACTC CTATTCAGAG 
GAAGAAAAGT ATGCCTTTGT CAACTGGATA AACAAAGCCC TGGAAAATGA TCCTGATTGT 
CGGCATGTCA TCCCAATGAA CCCAAACACG AATGATCTCT TTAATGCTGT TGGAGATGGC 
ATTGTCCTTT GTAAAATGAT CAACCTGTCA GTGCCAGACA CAATTGATGA AAGAACAATC 
AACAAAAAGA AGCTAACCCC TTTCACCATT CAGGAAAATC TGAACTTGGC TCTGAACTCT 
GCCTCAGCCA TCGGGTGCCA TGTGGTCAAC ATAGGGGCTG AGGACCTGAA GGAGGGGAAG 
CCTTATCTGG TCCTGGGACT TCTGTGGCAA GTCATCAAGA TTGGGTTGTT TGCTGACATT 
GAACTCAGCA GAAATGAAGC TCTGATTGCT CTTTTGAGAG AAGGTGAGAG CCTGGAGGAT 
TTGATGAAAC TCTCCCCTGA AGAGCTCTTG CTGAGGTGGG CTAATTACCA CCTGGAAAAT 
GCAGGCTGCA ACAAAATTGG CAACTTCAGT ACTGACATCA AGGACTCAAA AGCTTATTAC 
CACCTGCTTG AGCAGGTGGC TCCAAAAGGA GATGAAGAAG GTGTTCCTGC TGTTGTTATT 
GACATGTCAG GACTGCGGGA GAAGGATGAC ATCCAGAGGG CAGAATGCAT GCTGCAGCAG 
GCGGAGAGGC TGGGCTGCCG GCAGTTTGTC ACAGCCACAG ATGTTGTCCG AGGGAACCCC 
AAGTTGAACT TGGCTTTTAT TGCCAACCTC TTTAACAGAT ACCCTGCCCT GCACAAACCA 
GAGAACCAGG ACATTGACTG GGGGGCTCTT GAAGGTGAGA CGAGAGAAGA GCGGACATTT 
AGGAACTGGA TGAACTCCCT GGGTGTTAAC CCTCGAGTCA ATCATTTGTA CAGTGACTTA 
TCAGATGCCC TGGTCATCTT CCAGCTCTAT GAAAAGATCA AAGTTCCTGT TGACTGGAAC 
AGAGTAAACA AACCGCCATA CCCCAAACTG GGAGGCAATA TGAAGAAGCT TGAGAATTGT 
AACTACGCGG TAGAATTGGG GAAGAATCAA GCGAAGTTCT CCCTGGTTGG CATCGGTGGA 
CAAGATCTCA ATGAAGGAAA CCGCACTCTC ACACTGGCCT TGATTTGGCA GCTAATGAGA 
AGGTATACAC TGAATATCCT CGAAGAAATT GGTGGTGGCC AGAAGGTCAA TGATGACATT 
ATTGTCAACT GGGTGAATGA AACATTGAGG GAAGCAAAGA AAAGTTCATC CATCTCTAGT 
TTCAAGGACC CGAAGATTAG TACAAGTCTG CCTGTTCTGG ACCTCATCGA TGCCATCCAA 
CCAGGTTCCA TTAACTATGA CCTTCTGAAG ACAGAAAATC TGAATGATGA TGAGAAACTC 
AACAATGCAA AATATGCCAT CTCTATGGCC CGAAAAATTG GAGCAAGAGT GTATGCCCTG 
CCAGAAGACC TGGTTGAAGT GAACCCCAAA ATGGTCATGA CCGTGTTTGC CTGCCTCATG 
GGGAAAGGAA TGAAGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LCP1 ( XM_005266374.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005266431.1 Homo sapiens lymphocyte cytosolic protein 1 (LCP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17576
Clone ID Related Accession (Same CDS sequence)	NM_002298.5 , NM_002298.4 , XM_005266374.2 , XM_005266374.1
Accession Version	XM_005266374.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1884bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	plastin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000013.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAGAG GATCAGTGTC CGATGAGGAA ATGATGGAGC TCAGAGAAGC TTTTGCCAAA 
GTTGATACTG ATGGCAATGG ATACATCAGC TTCAATGAGT TGAATGACTT GTTCAAGGCT 
GCTTGCTTGC CTTTGCCTGG GTATAGAGTA CGAGAAATTA CAGAAAACCT GATGGCTACA 
GGTGATCTGG ACCAAGATGG AAGGATCAGC TTTGATGAGT TTATCAAGAT TTTCCATGGC 
CTAAAAAGCA CAGATGTTGC CAAGACCTTT AGAAAAGCAA TCAATAAGAA GGAAGGGATT 
TGTGCAATCG GTGGTACTTC AGAGCAGTCT AGCGTTGGCA CCCAACACTC CTATTCAGAG 
GAAGAAAAGT ATGCCTTTGT CAACTGGATA AACAAAGCCC TGGAAAATGA TCCTGATTGT 
CGGCATGTCA TCCCAATGAA CCCAAACACG AATGATCTCT TTAATGCTGT TGGAGATGGC 
ATTGTCCTTT GTAAAATGAT CAACCTGTCA GTGCCAGACA CAATTGATGA AAGAACAATC 
AACAAAAAGA AGCTAACCCC TTTCACCATT CAGGAAAATC TGAACTTGGC TCTGAACTCT 
GCCTCAGCCA TCGGGTGCCA TGTGGTCAAC ATAGGGGCTG AGGACCTGAA GGAGGGGAAG 
CCTTATCTGG TCCTGGGACT TCTGTGGCAA GTCATCAAGA TTGGGTTGTT TGCTGACATT 
GAACTCAGCA GAAATGAAGC TCTGATTGCT CTTTTGAGAG AAGGTGAGAG CCTGGAGGAT 
TTGATGAAAC TCTCCCCTGA AGAGCTCTTG CTGAGGTGGG CTAATTACCA CCTGGAAAAT 
GCAGGCTGCA ACAAAATTGG CAACTTCAGT ACTGACATCA AGGACTCAAA AGCTTATTAC 
CACCTGCTTG AGCAGGTGGC TCCAAAAGGA GATGAAGAAG GTGTTCCTGC TGTTGTTATT 
GACATGTCAG GACTGCGGGA GAAGGATGAC ATCCAGAGGG CAGAATGCAT GCTGCAGCAG 
GCGGAGAGGC TGGGCTGCCG GCAGTTTGTC ACAGCCACAG ATGTTGTCCG AGGGAACCCC 
AAGTTGAACT TGGCTTTTAT TGCCAACCTC TTTAACAGAT ACCCTGCCCT GCACAAACCA 
GAGAACCAGG ACATTGACTG GGGGGCTCTT GAAGGTGAGA CGAGAGAAGA GCGGACATTT 
AGGAACTGGA TGAACTCCCT GGGTGTTAAC CCTCGAGTCA ATCATTTGTA CAGTGACTTA 
TCAGATGCCC TGGTCATCTT CCAGCTCTAT GAAAAGATCA AAGTTCCTGT TGACTGGAAC 
AGAGTAAACA AACCGCCATA CCCCAAACTG GGAGGCAATA TGAAGAAGCT TGAGAATTGT 
AACTACGCGG TAGAATTGGG GAAGAATCAA GCGAAGTTCT CCCTGGTTGG CATCGGTGGA 
CAAGATCTCA ATGAAGGAAA CCGCACTCTC ACACTGGCCT TGATTTGGCA GCTAATGAGA 
AGGTATACAC TGAATATCCT CGAAGAAATT GGTGGTGGCC AGAAGGTCAA TGATGACATT 
ATTGTCAACT GGGTGAATGA AACATTGAGG GAAGCAAAGA AAAGTTCATC CATCTCTAGT 
TTCAAGGACC CGAAGATTAG TACAAGTCTG CCTGTTCTGG ACCTCATCGA TGCCATCCAA 
CCAGGTTCCA TTAACTATGA CCTTCTGAAG ACAGAAAATC TGAATGATGA TGAGAAACTC 
AACAATGCAA AATATGCCAT CTCTATGGCC CGAAAAATTG GAGCAAGAGT GTATGCCCTG 
CCAGAAGACC TGGTTGAAGT GAACCCCAAA ATGGTCATGA CCGTGTTTGC CTGCCTCATG 
GGGAAAGGAA TGAAGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005266431.1
CDS	137..2020
Translation	MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV

Target ORF information:

RefSeq Version	XM_005266374.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lymphocyte cytosolic protein 1 (LCP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005266374.1

ORF Insert Sequence:

ATGGCCAGAG GATCAGTGTC CGATGAGGAA ATGATGGAGC TCAGAGAAGC TTTTGCCAAA 
GTTGATACTG ATGGCAATGG ATACATCAGC TTCAATGAGT TGAATGACTT GTTCAAGGCT 
GCTTGCTTGC CTTTGCCTGG GTATAGAGTA CGAGAAATTA CAGAAAACCT GATGGCTACA 
GGTGATCTGG ACCAAGATGG AAGGATCAGC TTTGATGAGT TTATCAAGAT TTTCCATGGC 
CTAAAAAGCA CAGATGTTGC CAAGACCTTT AGAAAAGCAA TCAATAAGAA GGAAGGGATT 
TGTGCAATCG GTGGTACTTC AGAGCAGTCT AGCGTTGGCA CCCAACACTC CTATTCAGAG 
GAAGAAAAGT ATGCCTTTGT CAACTGGATA AACAAAGCCC TGGAAAATGA TCCTGATTGT 
CGGCATGTCA TCCCAATGAA CCCAAACACG AATGATCTCT TTAATGCTGT TGGAGATGGC 
ATTGTCCTTT GTAAAATGAT CAACCTGTCA GTGCCAGACA CAATTGATGA AAGAACAATC 
AACAAAAAGA AGCTAACCCC TTTCACCATT CAGGAAAATC TGAACTTGGC TCTGAACTCT 
GCCTCAGCCA TCGGGTGCCA TGTGGTCAAC ATAGGGGCTG AGGACCTGAA GGAGGGGAAG 
CCTTATCTGG TCCTGGGACT TCTGTGGCAA GTCATCAAGA TTGGGTTGTT TGCTGACATT 
GAACTCAGCA GAAATGAAGC TCTGATTGCT CTTTTGAGAG AAGGTGAGAG CCTGGAGGAT 
TTGATGAAAC TCTCCCCTGA AGAGCTCTTG CTGAGGTGGG CTAATTACCA CCTGGAAAAT 
GCAGGCTGCA ACAAAATTGG CAACTTCAGT ACTGACATCA AGGACTCAAA AGCTTATTAC 
CACCTGCTTG AGCAGGTGGC TCCAAAAGGA GATGAAGAAG GTGTTCCTGC TGTTGTTATT 
GACATGTCAG GACTGCGGGA GAAGGATGAC ATCCAGAGGG CAGAATGCAT GCTGCAGCAG 
GCGGAGAGGC TGGGCTGCCG GCAGTTTGTC ACAGCCACAG ATGTTGTCCG AGGGAACCCC 
AAGTTGAACT TGGCTTTTAT TGCCAACCTC TTTAACAGAT ACCCTGCCCT GCACAAACCA 
GAGAACCAGG ACATTGACTG GGGGGCTCTT GAAGGTGAGA CGAGAGAAGA GCGGACATTT 
AGGAACTGGA TGAACTCCCT GGGTGTTAAC CCTCGAGTCA ATCATTTGTA CAGTGACTTA 
TCAGATGCCC TGGTCATCTT CCAGCTCTAT GAAAAGATCA AAGTTCCTGT TGACTGGAAC 
AGAGTAAACA AACCGCCATA CCCCAAACTG GGAGGCAATA TGAAGAAGCT TGAGAATTGT 
AACTACGCGG TAGAATTGGG GAAGAATCAA GCGAAGTTCT CCCTGGTTGG CATCGGTGGA 
CAAGATCTCA ATGAAGGAAA CCGCACTCTC ACACTGGCCT TGATTTGGCA GCTAATGAGA 
AGGTATACAC TGAATATCCT CGAAGAAATT GGTGGTGGCC AGAAGGTCAA TGATGACATT 
ATTGTCAACT GGGTGAATGA AACATTGAGG GAAGCAAAGA AAAGTTCATC CATCTCTAGT 
TTCAAGGACC CGAAGATTAG TACAAGTCTG CCTGTTCTGG ACCTCATCGA TGCCATCCAA 
CCAGGTTCCA TTAACTATGA CCTTCTGAAG ACAGAAAATC TGAATGATGA TGAGAAACTC 
AACAATGCAA AATATGCCAT CTCTATGGCC CGAAAAATTG GAGCAAGAGT GTATGCCCTG 
CCAGAAGACC TGGTTGAAGT GAACCCCAAA ATGGTCATGA CCGTGTTTGC CTGCCTCATG 
GGGAAAGGAA TGAAGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Angiotensin II regulates phosphorylation of actin-associated proteins in human podocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(11)5019-5035(2017 Nov)
Schenk LK,M?ller-Kerutt A,Klosowski R,Wolters D,Schaffner-Reckinger E,Weide T,Pavenst?dt H,Vollenbr?ker B

AP4 modulated by the PI3K/AKT pathway promotes prostate cancer proliferation and metastasis of prostate cancer via upregulating L-plastin.
Cell death & disease8(10)e3060(2017 Oct)
Chen C,Cai Q,He W,Lam TB,Lin J,Zhao Y,Chen X,Gu P,Huang H,Xue M,Liu H,Su F,Huang J,Zheng J,Lin T

The Roles of Actin-Binding Domains 1 and 2 in the Calcium-Dependent Regulation of Actin Filament Bundling by Human Plastins.
Journal of molecular biology429(16)2490-2508(2017 Aug)
Schwebach CL,Agrawal R,Lindert S,Kudryashova E,Kudryashov DS

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LCP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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