L1CAM cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	L1CAM
Entrez Gene ID	3897
Full Name	L1 cell adhesion molecule
Synonyms	CAML1,CD171,HSAS,HSAS1,MASA,MIC5,N-CAM-L1,N-CAML1,NCAM-L1,S10,SPG1
General protein information	Preferred Names L1 cell adhesion molecule Names neural cell adhesion molecule L1 antigen identified by monoclonal antibody R1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq28
Summary	The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013].
Disorder MIM:	308840
Disorder Html:	Hydrocephalus due to aqueductal stenosis, 307000 (3); MASA syndrome, 303350 (3); CRASH syndrome, 303350 (3); Hydrocephalus with Hirschsprung disease, 307000 (3); Hydrocephalus with congenital idiopathic intestinal pseudoobstruction, 307000 (3); Corpus callosum, partial agenesis of, 304100 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000425.5	NP_000416.1	neural cell adhesion molecule L1 isoform 1 precursor
NM_001143963.2	NP_001137435.1	neural cell adhesion molecule L1 isoform 3 precursor
NM_000425.4	NP_000416.1	neural cell adhesion molecule L1 isoform 1 precursor
NM_024003.3	NP_076493.1	neural cell adhesion molecule L1 isoform 2 precursor
NM_001278116.1	NP_001265045.1	neural cell adhesion molecule L1 isoform 1 precursor
NM_001278116.2	NP_001265045.1	neural cell adhesion molecule L1 isoform 1 precursor

Pathways from BioSystems

Homologies

	L1CAM	XP_001087861.1
Gallus gallus (chicken)	L1CAM	NP_990484.1
Danio rerio (zebrafish)	nadl1.2	NP_571436.1
Danio rerio (zebrafish)	nadl1.1	NP_571458.1
Mus musculus (house mouse)	L1cam	NP_032504.3
Rattus norvegicus (Norway rat)	L1cam	NP_059041.1
Bos taurus (cattle)	L1CAM	NP_001179364.1
Xenopus tropicalis (tropical clawed frog)	l1cam	NP_001096185.1
Homo sapiens (human)	L1CAM	NP_000416.1
Pan troglodytes (chimpanzee)	L1CAM	NP_001180609.1
Canis lupus familiaris (dog)	L1CAM	XP_549364.2

Gene Ontology
Bibliography

Related articles in PubMed

Full-length L1CAM and not its ?2?27 splice variant promotes metastasis through induction of gelatinase expression.
Hauser S, Bickel L, Weinspach D, Gerg M, Sch?fer MK, Pfeifer M, Hazin J, Schelter F, Weidle UH, Ramser J, Volkmann J, Meindl A, Schmitt M, Schr?tzlmair F, Altevogt P, Kr?ger A
PloS one6(4)e18989(2011 Apr)

L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions.
Pfeifer M, Schirmer U, Geismann C, Sch?fer H, Sebens S, Altevogt P
BMC molecular biology1164(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that a deficiency in L1 may partially account for RTT phenotypes.
Title: The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome-derived neural precursor cells.

Data suggest that targeted therapy to neural cell adhesion molecule L1 (L1) might be effective in the treatment of retinoblastoma tumors.
Title: L1 increases adhesion-mediated proliferation and chemoresistance of retinoblastoma.

The differential expression timing of CD184 and CD171 permits identification and enrichment of RGCs from retinal organoids at differing maturation states from committed progenitors to differentiating neurons.
Title: Temporal expression of CD184(CXCR4) and CD171(L1CAM) identifies distinct early developmental stages of human retinal ganglion cells in embryonic stem cell derived retina.

This study examined the spatiotemporal distribution of L1CAM in the early human fetal period by means of immunohistochemistry and in situ hybridization. In advanced differentiated epithelia such as those of the gastrointestinal system, L1CAM localization vanishes. In epithelia, however, which undergo further development such as those of the urogenital system, L1CAM is further needed for their fully establishment.
Title: L1CAM in the Early Enteric and Urogenital System.

Mutations involving L1 cell adhesion molecule is associated with chemotherapy-resistant urothelial carcinoma.
Title: Clonal evolution of chemotherapy-resistant urothelial carcinoma.

The following L1CAM gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the L1CAM cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27607	NM_000425.5 Latest version!	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu27607	NM_001278116.2 Latest version!	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu16880	NM_001143963.2 Latest version!	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$881.30 $1259.00
OHu27467	NM_024003.3 Latest version!	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$888.30 $1269.00
View Old Accession Versions >>
OHu27607	NM_000425.4	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu27607	NM_001278116.1	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

L1CAM ( NM_000425.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000416.1 Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27607
Clone ID Related Accession (Same CDS sequence)	NM_000425.5 , NM_000425.4 , NM_001278116.1 , NM_001278116.2
Accession Version	NM_000425.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	neural cell adhesion molecule L1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY119527.1, BC126229.1 and BC025843.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_000425.4. Transcript Variant: This variant (1, also known as FL-L1CAM) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 4. Variants 1 and 4 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC136447.1, AK289754.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG GTCCCTGGAG 
AGTGACAACG AGGAGAAGGC CTTTGGCAGC AGCCAGCCAT CGCTCAACGG GGACATCAAG 
CCCCTGGGCA GTGACGACAG CCTGGCCGAT TATGGGGGCA GCGTGGATGT TCAGTTCAAC 
GAGGATGGTT CGTTCATTGG CCAGTACAGT GGCAAGAAGG AGAAGGAGGC GGCAGGGGGC 
AATGACAGCT CAGGGGCCAC TTCCCCCATC AACCCTGCCG TGGCCCTAGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000416.1
CDS	179..3952
Translation	MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE

Target ORF information:

RefSeq Version	NM_000425.5
Organism	Homo sapiens(human)
Definition	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000425.5

ORF Insert Sequence:

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG GTCCCTGGAG 
AGTGACAACG AGGAGAAGGC CTTTGGCAGC AGCCAGCCAT CGCTCAACGG GGACATCAAG 
CCCCTGGGCA GTGACGACAG CCTGGCCGAT TATGGGGGCA GCGTGGATGT TCAGTTCAAC 
GAGGATGGTT CGTTCATTGG CCAGTACAGT GGCAAGAAGG AGAAGGAGGC GGCAGGGGGC 
AATGACAGCT CAGGGGCCAC TTCCCCCATC AACCCTGCCG TGGCCCTAGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

L1CAM ( NM_000425.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000416.1 Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27607
Clone ID Related Accession (Same CDS sequence)	NM_000425.5 , NM_000425.4 , NM_001278116.1 , NM_001278116.2
Accession Version	NM_000425.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	neural cell adhesion molecule L1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY119527.1, BC126229.1, BC025843.1 and AI361399.1. This sequence is a reference standard in the RefSeqGene project. On May 11, 2013 this sequence version replaced NM_000425.3. Transcript Variant: This variant (1, also known as FL-L1CAM) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 4. Variants 1 and 4 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M77640.1, BC126229.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG GTCCCTGGAG 
AGTGACAACG AGGAGAAGGC CTTTGGCAGC AGCCAGCCAT CGCTCAACGG GGACATCAAG 
CCCCTGGGCA GTGACGACAG CCTGGCCGAT TATGGGGGCA GCGTGGATGT TCAGTTCAAC 
GAGGATGGTT CGTTCATTGG CCAGTACAGT GGCAAGAAGG AGAAGGAGGC GGCAGGGGGC 
AATGACAGCT CAGGGGCCAC TTCCCCCATC AACCCTGCCG TGGCCCTAGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000416.1
CDS	210..3983
Translation	MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE

Target ORF information:

RefSeq Version	NM_000425.4
Organism	Homo sapiens(human)
Definition	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000425.4

ORF Insert Sequence:

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG GTCCCTGGAG 
AGTGACAACG AGGAGAAGGC CTTTGGCAGC AGCCAGCCAT CGCTCAACGG GGACATCAAG 
CCCCTGGGCA GTGACGACAG CCTGGCCGAT TATGGGGGCA GCGTGGATGT TCAGTTCAAC 
GAGGATGGTT CGTTCATTGG CCAGTACAGT GGCAAGAAGG AGAAGGAGGC GGCAGGGGGC 
AATGACAGCT CAGGGGCCAC TTCCCCCATC AACCCTGCCG TGGCCCTAGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

L1CAM ( NM_001278116.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265045.1 Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 4, mRNA.

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CloneID	OHu27607
Clone ID Related Accession (Same CDS sequence)	NM_000425.5 , NM_000425.4 , NM_001278116.1 , NM_001278116.2
Accession Version	NM_001278116.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	neural cell adhesion molecule L1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA122729.1, BC126229.1, BC025843.1 and AI361399.1. Transcript Variant: This variant (4) represents the longest transcript and its 5' UTR structure is inferred based on experimental data in PMID 20799950. Variants 1 and 4 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: M77640.1, BC126229.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG GTCCCTGGAG 
AGTGACAACG AGGAGAAGGC CTTTGGCAGC AGCCAGCCAT CGCTCAACGG GGACATCAAG 
CCCCTGGGCA GTGACGACAG CCTGGCCGAT TATGGGGGCA GCGTGGATGT TCAGTTCAAC 
GAGGATGGTT CGTTCATTGG CCAGTACAGT GGCAAGAAGG AGAAGGAGGC GGCAGGGGGC 
AATGACAGCT CAGGGGCCAC TTCCCCCATC AACCCTGCCG TGGCCCTAGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265045.1
CDS	219..3992
Translation	MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE

Target ORF information:

RefSeq Version	NM_001278116.1
Organism	Homo sapiens(human)
Definition	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278116.1

ORF Insert Sequence:

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG GTCCCTGGAG 
AGTGACAACG AGGAGAAGGC CTTTGGCAGC AGCCAGCCAT CGCTCAACGG GGACATCAAG 
CCCCTGGGCA GTGACGACAG CCTGGCCGAT TATGGGGGCA GCGTGGATGT TCAGTTCAAC 
GAGGATGGTT CGTTCATTGG CCAGTACAGT GGCAAGAAGG AGAAGGAGGC GGCAGGGGGC 
AATGACAGCT CAGGGGCCAC TTCCCCCATC AACCCTGCCG TGGCCCTAGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

L1CAM ( NM_001278116.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265045.1 Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 4, mRNA.

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CloneID	OHu27607
Clone ID Related Accession (Same CDS sequence)	NM_000425.5 , NM_000425.4 , NM_001278116.1 , NM_001278116.2
Accession Version	NM_001278116.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	neural cell adhesion molecule L1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA122729.1, BC126229.1 and BC025843.1. On May 17, 2019 this sequence version replaced NM_001278116.1. Transcript Variant: This variant (4) represents the longest transcript and its 5' UTR structure is inferred based on experimental data in PMID 20799950. Variants 1 and 4 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AK289754.1, M77640.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000370060.7/ ENSP00000359077.1 RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG GTCCCTGGAG 
AGTGACAACG AGGAGAAGGC CTTTGGCAGC AGCCAGCCAT CGCTCAACGG GGACATCAAG 
CCCCTGGGCA GTGACGACAG CCTGGCCGAT TATGGGGGCA GCGTGGATGT TCAGTTCAAC 
GAGGATGGTT CGTTCATTGG CCAGTACAGT GGCAAGAAGG AGAAGGAGGC GGCAGGGGGC 
AATGACAGCT CAGGGGCCAC TTCCCCCATC AACCCTGCCG TGGCCCTAGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265045.1
CDS	218..3991
Translation	MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE

Target ORF information:

RefSeq Version	NM_001278116.2
Organism	Homo sapiens(human)
Definition	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278116.2

ORF Insert Sequence:

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG GTCCCTGGAG 
AGTGACAACG AGGAGAAGGC CTTTGGCAGC AGCCAGCCAT CGCTCAACGG GGACATCAAG 
CCCCTGGGCA GTGACGACAG CCTGGCCGAT TATGGGGGCA GCGTGGATGT TCAGTTCAAC 
GAGGATGGTT CGTTCATTGG CCAGTACAGT GGCAAGAAGG AGAAGGAGGC GGCAGGGGGC 
AATGACAGCT CAGGGGCCAC TTCCCCCATC AACCCTGCCG TGGCCCTAGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

L1CAM ( NM_001143963.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137435.1 Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16880
Clone ID Related Accession (Same CDS sequence)	NM_001143963.2
Accession Version	NM_001143963.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3747bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	neural cell adhesion molecule L1 isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC126229.1, EF506611.1, BC025843.1 and AI361399.1. On May 11, 2013 this sequence version replaced NM_001143963.1. Transcript Variant: This variant (3, also known as SV-L1CAM) lacks two alternate in-frame exons, one in the 5' coding region and the other (neuron-specific exon) in the 3' coding region, compared to variant 4. The resulting isoform (3) is shorter, and lacks an internal segment in the N-terminus and is missing a tyrosine-based sorting motif in the C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF506611.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATTGAT GGAGCCACCT GTCATCACGG AACAGTCTCC ACGGCGCCTG 
GTTGTCTTCC CCACAGATGA CATCAGCCTC AAGTGTGAGG CCAGTGGCAA GCCCGAAGTG 
CAGTTCCGCT GGACGAGGGA TGGTGTCCAC TTCAAACCCA AGGAAGAGCT GGGTGTGACC 
GTGTACCAGT CGCCCCACTC TGGCTCCTTC ACCATCACGG GCAACAACAG CAACTTTGCT 
CAGAGGTTCC AGGGCATCTA CCGCTGCTTT GCCAGCAATA AGCTGGGCAC CGCCATGTCC 
CATGAGATCC GGCTCATGGC CGAGGGTGCC CCCAAGTGGC CAAAGGAGAC AGTGAAGCCC 
GTGGAGGTGG AGGAAGGGGA GTCAGTGGTT CTGCCTTGCA ACCCTCCCCC AAGTGCAGAG 
CCTCTCCGGA TCTACTGGAT GAACAGCAAG ATCTTGCACA TCAAGCAGGA CGAGCGGGTG 
ACGATGGGCC AGAACGGCAA CCTCTACTTT GCCAATGTGC TCACCTCCGA CAACCACTCA 
GACTACATCT GCCACGCCCA CTTCCCAGGC ACCAGGACCA TCATTCAGAA GGAACCCATT 
GACCTCCGGG TCAAGGCCAC CAACAGCATG ATTGACAGGA AGCCGCGCCT GCTCTTCCCC 
ACCAACTCCA GCAGCCACCT GGTGGCCTTG CAGGGGCAGC CATTGGTCCT GGAGTGCATC 
GCCGAGGGCT TTCCCACGCC CACCATCAAA TGGCTGCGCC CCAGTGGCCC CATGCCAGCC 
GACCGTGTCA CCTACCAGAA CCACAACAAG ACCCTGCAGC TGCTGAAAGT GGGCGAGGAG 
GATGATGGCG AGTACCGCTG CCTGGCCGAG AACTCACTGG GCAGTGCCCG GCATGCGTAC 
TATGTCACCG TGGAGGCTGC CCCGTACTGG CTGCACAAGC CCCAGAGCCA TCTATATGGG 
CCAGGAGAGA CTGCCCGCCT GGACTGCCAA GTCCAGGGCA GGCCCCAACC AGAGGTCACC 
TGGAGAATCA ACGGGATCCC TGTGGAGGAG CTGGCCAAAG ACCAGAAGTA CCGGATTCAG 
CGTGGCGCCC TGATCCTGAG CAACGTGCAG CCCAGTGACA CAATGGTGAC CCAATGTGAG 
GCCCGCAACC GGCACGGGCT CTTGCTGGCC AATGCCTACA TCTACGTTGT CCAGCTGCCA 
GCCAAGATCC TGACTGCGGA CAATCAGACG TACATGGCTG TCCAGGGCAG CACTGCCTAC 
CTTCTGTGCA AGGCCTTCGG AGCGCCTGTG CCCAGTGTTC AGTGGCTGGA CGAGGATGGG 
ACAACAGTGC TTCAGGACGA ACGCTTCTTC CCCTATGCCA ATGGGACCCT GGGCATTCGA 
GACCTCCAGG CCAATGACAC CGGACGCTAC TTCTGCCTGG CTGCCAATGA CCAAAACAAT 
GTTACCATCA TGGCTAACCT GAAGGTTAAA GATGCAACTC AGATCACTCA GGGGCCCCGC 
AGCACAATCG AGAAGAAAGG TTCCAGGGTG ACCTTCACGT GCCAGGCCTC CTTTGACCCC 
TCCTTGCAGC CCAGCATCAC CTGGCGTGGG GACGGTCGAG ACCTCCAGGA GCTTGGGGAC 
AGTGACAAGT ACTTCATAGA GGATGGGCGC CTGGTCATCC ACAGCCTGGA CTACAGCGAC 
CAGGGCAACT ACAGCTGCGT GGCCAGTACC GAACTGGATG TGGTGGAGAG TAGGGCACAG 
CTCTTGGTGG TGGGGAGCCC TGGGCCGGTG CCACGGCTGG TGCTGTCCGA CCTGCACCTG 
CTGACGCAGA GCCAGGTGCG CGTGTCCTGG AGTCCTGCAG AAGACCACAA TGCCCCCATT 
GAGAAATATG ACATTGAATT TGAGGACAAG GAAATGGCGC CTGAAAAATG GTACAGTCTG 
GGCAAGGTTC CAGGGAACCA GACCTCTACC ACCCTCAAGC TGTCGCCCTA TGTCCACTAC 
ACCTTTAGGG TTACTGCCAT AAACAAATAT GGCCCCGGGG AGCCCAGCCC GGTCTCTGAG 
ACTGTGGTCA CACCTGAGGC AGCCCCAGAG AAGAACCCTG TGGATGTGAA GGGGGAAGGA 
AATGAGACCA CCAATATGGT CATCACGTGG AAGCCGCTCC GGTGGATGGA CTGGAACGCC 
CCCCAGGTTC AGTACCGCGT GCAGTGGCGC CCTCAGGGGA CACGAGGGCC CTGGCAGGAG 
CAGATTGTCA GCGACCCCTT CCTGGTGGTG TCCAACACGT CCACCTTCGT GCCCTATGAG 
ATCAAAGTCC AGGCCGTCAA CAGCCAGGGC AAGGGACCAG AGCCCCAGGT CACTATCGGC 
TACTCTGGAG AGGACTACCC CCAGGCAATC CCTGAGCTGG AAGGCATTGA AATCCTCAAC 
TCAAGTGCCG TGCTGGTCAA GTGGCGGCCG GTGGACCTGG CCCAGGTCAA GGGCCACCTC 
CGCGGATACA ATGTGACGTA CTGGAGGGAG GGCAGTCAGA GGAAGCACAG CAAGAGACAT 
ATCCACAAAG ACCATGTGGT GGTGCCCGCC AACACCACCA GTGTCATCCT CAGTGGCTTG 
CGGCCCTATA GCTCCTACCA CCTGGAGGTG CAGGCCTTTA ACGGGCGAGG ATCGGGGCCC 
GCCAGCGAGT TCACCTTCAG CACCCCAGAG GGAGTGCCTG GCCACCCCGA GGCGTTGCAC 
CTGGAGTGCC AGTCGAACAC CAGCCTGCTG CTGCGCTGGC AGCCCCCACT CAGCCACAAC 
GGCGTGCTCA CCGGCTACGT GCTCTCCTAC CACCCCCTGG ATGAGGGGGG CAAGGGGCAA 
CTGTCCTTCA ACCTTCGGGA CCCCGAACTT CGGACACACA ACCTGACCGA TCTCAGCCCC 
CACCTGCGGT ACCGCTTCCA GCTTCAGGCC ACCACCAAAG AGGGCCCTGG TGAAGCCATC 
GTACGGGAAG GAGGCACTAT GGCCTTGTCT GGGATCTCAG ATTTTGGCAA CATCTCAGCC 
ACAGCGGGTG AAAACTACAG TGTCGTCTCC TGGGTCCCCA AGGAGGGCCA GTGCAACTTC 
AGGTTCCATA TCTTGTTCAA AGCCTTGGGA GAAGAGAAGG GTGGGGCTTC CCTTTCGCCA 
CAGTATGTCA GCTACAACCA GAGCTCCTAC ACGCAGTGGG ACCTGCAGCC TGACACTGAC 
TACGAGATCC ACTTGTTTAA GGAGAGGATG TTCCGGCACC AAATGGCTGT GAAGACCAAT 
GGCACAGGCC GCGTGAGGCT CCCTCCTGCT GGCTTCGCCA CTGAGGGCTG GTTCATCGGC 
TTTGTGAGTG CCATCATCCT CCTGCTCCTC GTCCTGCTCA TCCTCTGCTT CATCAAGCGC 
AGCAAGGGCG GCAAATACTC AGTGAAGGAT AAGGAGGACA CCCAGGTGGA CTCTGAGGCC 
CGACCGATGA AAGATGAGAC CTTCGGCGAG TACAGTGACA ACGAGGAGAA GGCCTTTGGC 
AGCAGCCAGC CATCGCTCAA CGGGGACATC AAGCCCCTGG GCAGTGACGA CAGCCTGGCC 
GATTATGGGG GCAGCGTGGA TGTTCAGTTC AACGAGGATG GTTCGTTCAT TGGCCAGTAC 
AGTGGCAAGA AGGAGAAGGA GGCGGCAGGG GGCAATGACA GCTCAGGGGC CACTTCCCCC 
ATCAACCCTG CCGTGGCCCT AGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137435.1
CDS	109..3855
Translation	MVVALRYVWPLLLCSPCLLIQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE

Target ORF information:

RefSeq Version	NM_001143963.2
Organism	Homo sapiens(human)
Definition	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143963.2

ORF Insert Sequence:

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATTGAT GGAGCCACCT GTCATCACGG AACAGTCTCC ACGGCGCCTG 
GTTGTCTTCC CCACAGATGA CATCAGCCTC AAGTGTGAGG CCAGTGGCAA GCCCGAAGTG 
CAGTTCCGCT GGACGAGGGA TGGTGTCCAC TTCAAACCCA AGGAAGAGCT GGGTGTGACC 
GTGTACCAGT CGCCCCACTC TGGCTCCTTC ACCATCACGG GCAACAACAG CAACTTTGCT 
CAGAGGTTCC AGGGCATCTA CCGCTGCTTT GCCAGCAATA AGCTGGGCAC CGCCATGTCC 
CATGAGATCC GGCTCATGGC CGAGGGTGCC CCCAAGTGGC CAAAGGAGAC AGTGAAGCCC 
GTGGAGGTGG AGGAAGGGGA GTCAGTGGTT CTGCCTTGCA ACCCTCCCCC AAGTGCAGAG 
CCTCTCCGGA TCTACTGGAT GAACAGCAAG ATCTTGCACA TCAAGCAGGA CGAGCGGGTG 
ACGATGGGCC AGAACGGCAA CCTCTACTTT GCCAATGTGC TCACCTCCGA CAACCACTCA 
GACTACATCT GCCACGCCCA CTTCCCAGGC ACCAGGACCA TCATTCAGAA GGAACCCATT 
GACCTCCGGG TCAAGGCCAC CAACAGCATG ATTGACAGGA AGCCGCGCCT GCTCTTCCCC 
ACCAACTCCA GCAGCCACCT GGTGGCCTTG CAGGGGCAGC CATTGGTCCT GGAGTGCATC 
GCCGAGGGCT TTCCCACGCC CACCATCAAA TGGCTGCGCC CCAGTGGCCC CATGCCAGCC 
GACCGTGTCA CCTACCAGAA CCACAACAAG ACCCTGCAGC TGCTGAAAGT GGGCGAGGAG 
GATGATGGCG AGTACCGCTG CCTGGCCGAG AACTCACTGG GCAGTGCCCG GCATGCGTAC 
TATGTCACCG TGGAGGCTGC CCCGTACTGG CTGCACAAGC CCCAGAGCCA TCTATATGGG 
CCAGGAGAGA CTGCCCGCCT GGACTGCCAA GTCCAGGGCA GGCCCCAACC AGAGGTCACC 
TGGAGAATCA ACGGGATCCC TGTGGAGGAG CTGGCCAAAG ACCAGAAGTA CCGGATTCAG 
CGTGGCGCCC TGATCCTGAG CAACGTGCAG CCCAGTGACA CAATGGTGAC CCAATGTGAG 
GCCCGCAACC GGCACGGGCT CTTGCTGGCC AATGCCTACA TCTACGTTGT CCAGCTGCCA 
GCCAAGATCC TGACTGCGGA CAATCAGACG TACATGGCTG TCCAGGGCAG CACTGCCTAC 
CTTCTGTGCA AGGCCTTCGG AGCGCCTGTG CCCAGTGTTC AGTGGCTGGA CGAGGATGGG 
ACAACAGTGC TTCAGGACGA ACGCTTCTTC CCCTATGCCA ATGGGACCCT GGGCATTCGA 
GACCTCCAGG CCAATGACAC CGGACGCTAC TTCTGCCTGG CTGCCAATGA CCAAAACAAT 
GTTACCATCA TGGCTAACCT GAAGGTTAAA GATGCAACTC AGATCACTCA GGGGCCCCGC 
AGCACAATCG AGAAGAAAGG TTCCAGGGTG ACCTTCACGT GCCAGGCCTC CTTTGACCCC 
TCCTTGCAGC CCAGCATCAC CTGGCGTGGG GACGGTCGAG ACCTCCAGGA GCTTGGGGAC 
AGTGACAAGT ACTTCATAGA GGATGGGCGC CTGGTCATCC ACAGCCTGGA CTACAGCGAC 
CAGGGCAACT ACAGCTGCGT GGCCAGTACC GAACTGGATG TGGTGGAGAG TAGGGCACAG 
CTCTTGGTGG TGGGGAGCCC TGGGCCGGTG CCACGGCTGG TGCTGTCCGA CCTGCACCTG 
CTGACGCAGA GCCAGGTGCG CGTGTCCTGG AGTCCTGCAG AAGACCACAA TGCCCCCATT 
GAGAAATATG ACATTGAATT TGAGGACAAG GAAATGGCGC CTGAAAAATG GTACAGTCTG 
GGCAAGGTTC CAGGGAACCA GACCTCTACC ACCCTCAAGC TGTCGCCCTA TGTCCACTAC 
ACCTTTAGGG TTACTGCCAT AAACAAATAT GGCCCCGGGG AGCCCAGCCC GGTCTCTGAG 
ACTGTGGTCA CACCTGAGGC AGCCCCAGAG AAGAACCCTG TGGATGTGAA GGGGGAAGGA 
AATGAGACCA CCAATATGGT CATCACGTGG AAGCCGCTCC GGTGGATGGA CTGGAACGCC 
CCCCAGGTTC AGTACCGCGT GCAGTGGCGC CCTCAGGGGA CACGAGGGCC CTGGCAGGAG 
CAGATTGTCA GCGACCCCTT CCTGGTGGTG TCCAACACGT CCACCTTCGT GCCCTATGAG 
ATCAAAGTCC AGGCCGTCAA CAGCCAGGGC AAGGGACCAG AGCCCCAGGT CACTATCGGC 
TACTCTGGAG AGGACTACCC CCAGGCAATC CCTGAGCTGG AAGGCATTGA AATCCTCAAC 
TCAAGTGCCG TGCTGGTCAA GTGGCGGCCG GTGGACCTGG CCCAGGTCAA GGGCCACCTC 
CGCGGATACA ATGTGACGTA CTGGAGGGAG GGCAGTCAGA GGAAGCACAG CAAGAGACAT 
ATCCACAAAG ACCATGTGGT GGTGCCCGCC AACACCACCA GTGTCATCCT CAGTGGCTTG 
CGGCCCTATA GCTCCTACCA CCTGGAGGTG CAGGCCTTTA ACGGGCGAGG ATCGGGGCCC 
GCCAGCGAGT TCACCTTCAG CACCCCAGAG GGAGTGCCTG GCCACCCCGA GGCGTTGCAC 
CTGGAGTGCC AGTCGAACAC CAGCCTGCTG CTGCGCTGGC AGCCCCCACT CAGCCACAAC 
GGCGTGCTCA CCGGCTACGT GCTCTCCTAC CACCCCCTGG ATGAGGGGGG CAAGGGGCAA 
CTGTCCTTCA ACCTTCGGGA CCCCGAACTT CGGACACACA ACCTGACCGA TCTCAGCCCC 
CACCTGCGGT ACCGCTTCCA GCTTCAGGCC ACCACCAAAG AGGGCCCTGG TGAAGCCATC 
GTACGGGAAG GAGGCACTAT GGCCTTGTCT GGGATCTCAG ATTTTGGCAA CATCTCAGCC 
ACAGCGGGTG AAAACTACAG TGTCGTCTCC TGGGTCCCCA AGGAGGGCCA GTGCAACTTC 
AGGTTCCATA TCTTGTTCAA AGCCTTGGGA GAAGAGAAGG GTGGGGCTTC CCTTTCGCCA 
CAGTATGTCA GCTACAACCA GAGCTCCTAC ACGCAGTGGG ACCTGCAGCC TGACACTGAC 
TACGAGATCC ACTTGTTTAA GGAGAGGATG TTCCGGCACC AAATGGCTGT GAAGACCAAT 
GGCACAGGCC GCGTGAGGCT CCCTCCTGCT GGCTTCGCCA CTGAGGGCTG GTTCATCGGC 
TTTGTGAGTG CCATCATCCT CCTGCTCCTC GTCCTGCTCA TCCTCTGCTT CATCAAGCGC 
AGCAAGGGCG GCAAATACTC AGTGAAGGAT AAGGAGGACA CCCAGGTGGA CTCTGAGGCC 
CGACCGATGA AAGATGAGAC CTTCGGCGAG TACAGTGACA ACGAGGAGAA GGCCTTTGGC 
AGCAGCCAGC CATCGCTCAA CGGGGACATC AAGCCCCTGG GCAGTGACGA CAGCCTGGCC 
GATTATGGGG GCAGCGTGGA TGTTCAGTTC AACGAGGATG GTTCGTTCAT TGGCCAGTAC 
AGTGGCAAGA AGGAGAAGGA GGCGGCAGGG GGCAATGACA GCTCAGGGGC CACTTCCCCC 
ATCAACCCTG CCGTGGCCCT AGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

L1CAM ( NM_024003.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_076493.1 Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 2, mRNA.

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CloneID	OHu27467
Clone ID Related Accession (Same CDS sequence)	NM_024003.3
Accession Version	NM_024003.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	neural cell adhesion molecule L1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC126229.1, M74387.1, BC025843.1 and AI361399.1. On May 11, 2013 this sequence version replaced NM_024003.2. Transcript Variant: This variant (2) lacks an alternate in-frame neuron-specific exon in the 3' coding region, compared to variant 4. The resulting isoform (2) is shorter and lacks an internal segment containing a tyrosine-based sorting motif, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M74387.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG TGACAACGAG 
GAGAAGGCCT TTGGCAGCAG CCAGCCATCG CTCAACGGGG ACATCAAGCC CCTGGGCAGT 
GACGACAGCC TGGCCGATTA TGGGGGCAGC GTGGATGTTC AGTTCAACGA GGATGGTTCG 
TTCATTGGCC AGTACAGTGG CAAGAAGGAG AAGGAGGCGG CAGGGGGCAA TGACAGCTCA 
GGGGCCACTT CCCCCATCAA CCCTGCCGTG GCCCTAGAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076493.1
CDS	109..3870
Translation	MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE

Target ORF information:

RefSeq Version	NM_024003.3
Organism	Homo sapiens(human)
Definition	Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024003.3

ORF Insert Sequence:

ATGGTCGTGG CGCTGCGGTA CGTGTGGCCT CTCCTCCTCT GCAGCCCCTG CCTGCTTATC 
CAGATCCCCG AGGAATATGA AGGACACCAT GTGATGGAGC CACCTGTCAT CACGGAACAG 
TCTCCACGGC GCCTGGTTGT CTTCCCCACA GATGACATCA GCCTCAAGTG TGAGGCCAGT 
GGCAAGCCCG AAGTGCAGTT CCGCTGGACG AGGGATGGTG TCCACTTCAA ACCCAAGGAA 
GAGCTGGGTG TGACCGTGTA CCAGTCGCCC CACTCTGGCT CCTTCACCAT CACGGGCAAC 
AACAGCAACT TTGCTCAGAG GTTCCAGGGC ATCTACCGCT GCTTTGCCAG CAATAAGCTG 
GGCACCGCCA TGTCCCATGA GATCCGGCTC ATGGCCGAGG GTGCCCCCAA GTGGCCAAAG 
GAGACAGTGA AGCCCGTGGA GGTGGAGGAA GGGGAGTCAG TGGTTCTGCC TTGCAACCCT 
CCCCCAAGTG CAGAGCCTCT CCGGATCTAC TGGATGAACA GCAAGATCTT GCACATCAAG 
CAGGACGAGC GGGTGACGAT GGGCCAGAAC GGCAACCTCT ACTTTGCCAA TGTGCTCACC 
TCCGACAACC ACTCAGACTA CATCTGCCAC GCCCACTTCC CAGGCACCAG GACCATCATT 
CAGAAGGAAC CCATTGACCT CCGGGTCAAG GCCACCAACA GCATGATTGA CAGGAAGCCG 
CGCCTGCTCT TCCCCACCAA CTCCAGCAGC CACCTGGTGG CCTTGCAGGG GCAGCCATTG 
GTCCTGGAGT GCATCGCCGA GGGCTTTCCC ACGCCCACCA TCAAATGGCT GCGCCCCAGT 
GGCCCCATGC CAGCCGACCG TGTCACCTAC CAGAACCACA ACAAGACCCT GCAGCTGCTG 
AAAGTGGGCG AGGAGGATGA TGGCGAGTAC CGCTGCCTGG CCGAGAACTC ACTGGGCAGT 
GCCCGGCATG CGTACTATGT CACCGTGGAG GCTGCCCCGT ACTGGCTGCA CAAGCCCCAG 
AGCCATCTAT ATGGGCCAGG AGAGACTGCC CGCCTGGACT GCCAAGTCCA GGGCAGGCCC 
CAACCAGAGG TCACCTGGAG AATCAACGGG ATCCCTGTGG AGGAGCTGGC CAAAGACCAG 
AAGTACCGGA TTCAGCGTGG CGCCCTGATC CTGAGCAACG TGCAGCCCAG TGACACAATG 
GTGACCCAAT GTGAGGCCCG CAACCGGCAC GGGCTCTTGC TGGCCAATGC CTACATCTAC 
GTTGTCCAGC TGCCAGCCAA GATCCTGACT GCGGACAATC AGACGTACAT GGCTGTCCAG 
GGCAGCACTG CCTACCTTCT GTGCAAGGCC TTCGGAGCGC CTGTGCCCAG TGTTCAGTGG 
CTGGACGAGG ATGGGACAAC AGTGCTTCAG GACGAACGCT TCTTCCCCTA TGCCAATGGG 
ACCCTGGGCA TTCGAGACCT CCAGGCCAAT GACACCGGAC GCTACTTCTG CCTGGCTGCC 
AATGACCAAA ACAATGTTAC CATCATGGCT AACCTGAAGG TTAAAGATGC AACTCAGATC 
ACTCAGGGGC CCCGCAGCAC AATCGAGAAG AAAGGTTCCA GGGTGACCTT CACGTGCCAG 
GCCTCCTTTG ACCCCTCCTT GCAGCCCAGC ATCACCTGGC GTGGGGACGG TCGAGACCTC 
CAGGAGCTTG GGGACAGTGA CAAGTACTTC ATAGAGGATG GGCGCCTGGT CATCCACAGC 
CTGGACTACA GCGACCAGGG CAACTACAGC TGCGTGGCCA GTACCGAACT GGATGTGGTG 
GAGAGTAGGG CACAGCTCTT GGTGGTGGGG AGCCCTGGGC CGGTGCCACG GCTGGTGCTG 
TCCGACCTGC ACCTGCTGAC GCAGAGCCAG GTGCGCGTGT CCTGGAGTCC TGCAGAAGAC 
CACAATGCCC CCATTGAGAA ATATGACATT GAATTTGAGG ACAAGGAAAT GGCGCCTGAA 
AAATGGTACA GTCTGGGCAA GGTTCCAGGG AACCAGACCT CTACCACCCT CAAGCTGTCG 
CCCTATGTCC ACTACACCTT TAGGGTTACT GCCATAAACA AATATGGCCC CGGGGAGCCC 
AGCCCGGTCT CTGAGACTGT GGTCACACCT GAGGCAGCCC CAGAGAAGAA CCCTGTGGAT 
GTGAAGGGGG AAGGAAATGA GACCACCAAT ATGGTCATCA CGTGGAAGCC GCTCCGGTGG 
ATGGACTGGA ACGCCCCCCA GGTTCAGTAC CGCGTGCAGT GGCGCCCTCA GGGGACACGA 
GGGCCCTGGC AGGAGCAGAT TGTCAGCGAC CCCTTCCTGG TGGTGTCCAA CACGTCCACC 
TTCGTGCCCT ATGAGATCAA AGTCCAGGCC GTCAACAGCC AGGGCAAGGG ACCAGAGCCC 
CAGGTCACTA TCGGCTACTC TGGAGAGGAC TACCCCCAGG CAATCCCTGA GCTGGAAGGC 
ATTGAAATCC TCAACTCAAG TGCCGTGCTG GTCAAGTGGC GGCCGGTGGA CCTGGCCCAG 
GTCAAGGGCC ACCTCCGCGG ATACAATGTG ACGTACTGGA GGGAGGGCAG TCAGAGGAAG 
CACAGCAAGA GACATATCCA CAAAGACCAT GTGGTGGTGC CCGCCAACAC CACCAGTGTC 
ATCCTCAGTG GCTTGCGGCC CTATAGCTCC TACCACCTGG AGGTGCAGGC CTTTAACGGG 
CGAGGATCGG GGCCCGCCAG CGAGTTCACC TTCAGCACCC CAGAGGGAGT GCCTGGCCAC 
CCCGAGGCGT TGCACCTGGA GTGCCAGTCG AACACCAGCC TGCTGCTGCG CTGGCAGCCC 
CCACTCAGCC ACAACGGCGT GCTCACCGGC TACGTGCTCT CCTACCACCC CCTGGATGAG 
GGGGGCAAGG GGCAACTGTC CTTCAACCTT CGGGACCCCG AACTTCGGAC ACACAACCTG 
ACCGATCTCA GCCCCCACCT GCGGTACCGC TTCCAGCTTC AGGCCACCAC CAAAGAGGGC 
CCTGGTGAAG CCATCGTACG GGAAGGAGGC ACTATGGCCT TGTCTGGGAT CTCAGATTTT 
GGCAACATCT CAGCCACAGC GGGTGAAAAC TACAGTGTCG TCTCCTGGGT CCCCAAGGAG 
GGCCAGTGCA ACTTCAGGTT CCATATCTTG TTCAAAGCCT TGGGAGAAGA GAAGGGTGGG 
GCTTCCCTTT CGCCACAGTA TGTCAGCTAC AACCAGAGCT CCTACACGCA GTGGGACCTG 
CAGCCTGACA CTGACTACGA GATCCACTTG TTTAAGGAGA GGATGTTCCG GCACCAAATG 
GCTGTGAAGA CCAATGGCAC AGGCCGCGTG AGGCTCCCTC CTGCTGGCTT CGCCACTGAG 
GGCTGGTTCA TCGGCTTTGT GAGTGCCATC ATCCTCCTGC TCCTCGTCCT GCTCATCCTC 
TGCTTCATCA AGCGCAGCAA GGGCGGCAAA TACTCAGTGA AGGATAAGGA GGACACCCAG 
GTGGACTCTG AGGCCCGACC GATGAAAGAT GAGACCTTCG GCGAGTACAG TGACAACGAG 
GAGAAGGCCT TTGGCAGCAG CCAGCCATCG CTCAACGGGG ACATCAAGCC CCTGGGCAGT 
GACGACAGCC TGGCCGATTA TGGGGGCAGC GTGGATGTTC AGTTCAACGA GGATGGTTCG 
TTCATTGGCC AGTACAGTGG CAAGAAGGAG AAGGAGGCGG CAGGGGGCAA TGACAGCTCA 
GGGGCCACTT CCCCCATCAA CCCTGCCGTG GCCCTAGAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Full-length L1CAM and not its ?2?27 splice variant promotes metastasis through induction of gelatinase expression.
PloS one6(4)e18989(2011 Apr)
Hauser S,Bickel L,Weinspach D,Gerg M,Sch?fer MK,Pfeifer M,Hazin J,Schelter F,Weidle UH,Ramser J,Volkmann J,Meindl A,Schmitt M,Schr?tzlmair F,Altevogt P,Kr?ger A

L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions.
BMC molecular biology1164(2010 Aug)
Pfeifer M,Schirmer U,Geismann C,Sch?fer H,Sebens S,Altevogt P

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L1CAM cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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