gRNAs
The following PROB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PROB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu12366 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001161546.2 , NM_001161546.1 | |
| Accession Version | NM_001161546.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3048bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-24 | |
| Organism | Homo sapiens(human) | |
| Product | proline-rich basic protein 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AW576390.1, AC135457.2 and AK316483.1. On May 17, 2019 this sequence version replaced NM_001161546.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000434752.4/ ENSP00000416033.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## | |
1 | ATGCTGACCG CGCTCGCCCC GCCAGCCCTG CCTGGGATCC CGAGGCAGCT GCCCACGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001155018.1 |
| CDS | 24..3071 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001161546.2 |
1 | ATGCTGACCG CGCTCGCCCC GCCAGCCCTG CCTGGGATCC CGAGGCAGCT GCCCACGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu12366 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001161546.2 , NM_001161546.1 | |
| Accession Version | NM_001161546.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3048bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-06-23 | |
| Organism | Homo sapiens(human) | |
| Product | proline-rich basic protein 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AW576390.1, AC135457.2 and AK316483.1. On or before Jul 18, 2009 this sequence version replaced XM_374142.4, XM_001721165.2, XM_001722732.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. | |
1 | ATGCTGACCG CGCTCGCCCC GCCAGCCCTG CCTGGGATCC CGAGGCAGCT GCCCACGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001155018.1 |
| CDS | 116..3163 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001161546.1 |
1 | ATGCTGACCG CGCTCGCCCC GCCAGCCCTG CCTGGGATCC CGAGGCAGCT GCCCACGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Variants in SKP1, PROB1, and IL17B genes at keratoconus 5q31.1-q35.3 susceptibility locus identified by whole-exome sequencing. |
Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis. |
