KRT84 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRT84
Entrez Gene ID	3890
Full Name	keratin 84
Synonyms	HB4,KRTHB4
General protein information	Preferred Names keratin 84 Names keratin, type II cuticular Hb4 K84 hard keratin, type II, 4 keratin 84, type II keratin, hair, basic, 4 type II hair keratin 4 type II hair keratin Hb4 type-II keratin Kb24
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.13
Summary	The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin is contained primarily in the filiform tongue papilla, among other hair keratins. [provided by RefSeq, Jul 2008].
Disorder MIM:	602766

mRNA and Protein(s)

mRNA	Protein	Name
XM_011538335.2	XP_011536637.1	keratin, type II cuticular Hb4 isoform X1
NM_033045.4	NP_149034.2	keratin, type II cuticular Hb4
NM_033045.3	NP_149034.2	keratin, type II cuticular Hb4

Pathways from BioSystems

Homologies

	KRT84	XP_001093676.1
Rattus norvegicus (Norway rat)	Krt84	NP_001008812.1
Mus musculus (house mouse)	Krt84	NP_032500.2
Pan troglodytes (chimpanzee)	KRT84	XP_522389.2
Canis lupus familiaris (dog)	KRT84	XP_543652.1
Bos taurus (cattle)	KRT84	NP_001179264.1
Homo sapiens (human)	KRT84	NP_149034.2
Danio rerio (zebrafish)	si:dkey-222f2.1	XP_696736.2

Gene Ontology
Bibliography

Related articles in PubMed

New consensus nomenclature for mammalian keratins.
Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW
The Journal of cell biology174(2)169-74(2006 Jul)

Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13.
Rogers MA, Edler L, Winter H, Langbein L, Beckmann I, Schweizer J
The Journal of investigative dermatology124(3)536-44(2005 Mar)

Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.
Rogers MA, Winter H, Langbein L, Wolf C, Schweizer J
The Journal of investigative dermatology114(3)464-72(2000 Mar)

The complement of native alpha-keratin polypeptides of hair-forming cells: a subset of eight polypeptides that differ from epithelial cytokeratins.
Heid HW, Werner E, Franke WW
Differentiation; research in biological diversity32(2)101-19(1986)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KRT84 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRT84 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19075	NM_033045.4 Latest version!	Homo sapiens keratin 84 (KRT84), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu19075	XM_011538335.2 Latest version!	Homo sapiens keratin 84 (KRT84), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu19075	NM_033045.3	Homo sapiens keratin 84 (KRT84), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRT84 ( NM_033045.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_149034.2 Homo sapiens keratin 84 (KRT84), mRNA.

Price & Availability↑

CloneID	OHu19075
Clone ID Related Accession (Same CDS sequence)	XM_011538335.2 , NM_033045.4 , NM_033045.3
Accession Version	NM_033045.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	keratin, type II cuticular Hb4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC078865.22 and BC069647.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_033045.3. ##Evidence-Data-START## Transcript exon combination :: BC069647.1, AK314030.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000257951.3/ ENSP00000257951.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 5' end.

ATGTCTTGCC GCTCCTACCG AGTCAGCTCT GGTCACCGGG TGGGCAACTT CAGCTCTTGT 
TCAGCAATGA CACCACAGAA CCTGAATCGC TTCCGGGCCA ACTCTGTCTC CTGTTGGAGT 
GGGCCTGGAT TCCGGGGCCT TGGCAGCTTT GGTAGTCGGA GTGTCATCAC CTTTGGATCG 
TACTCACCCC GGATAGCAGC TGTAGGCTCT CGGCCCATCC ACTGTGGAGT CCGCTTTGGT 
GCTGGCTGTG GGATGGGTTT TGGTGATGGG AGAGGTGTTG GTCTGGGGCC TAGGGCTGAC 
AGCTGTGTTG GTCTGGGCTT TGGAGCTGGC AGTGGCATTG GCTATGGCTT TGGTGGCCCT 
GGCTTTGGTT ACAGAGTTGG AGGGGTTGGA GTCCCAGCAG CCCCATCTAT CACAGCTGTG 
ACTGTGAACA AGAGCCTACT GACCCCCCTC AACCTGGAGA TTGACCCCAA TGCCCAGAGG 
GTGAAGAAGG ATGAGAAGGA GCAAATCAAG ACCCTCAACA ACAAGTTTGC CTCCTTCATT 
GACAAGGTTC GGTTCCTAGA GCAGCAGAAT AAGCTCCTAG AGACCAAGTG GAGCTTCCTC 
CAAGAGCAGA AATGTATCAG GAGCAATCTG GAGCCACTCT TCGAGAGCTA CATCACCAAC 
CTGCGGAGGC AGTTGGAGGT GCTGGTCAGT GATCAGGCCC GGCTCCAGGC TGAGAGGAAC 
CACCTGCAGG ATGTCCTAGA GGGCTTCAAG AAGAAGTATG AAGAGGAAGT GGTATGTCGG 
GCCAATGCTG AGAATGAGTT TGTGGCTCTG AAGAAGGATG TGGATGCAGC TTTCATGAAC 
AAGTCTGATC TCGAGGCCAA CGTGGATACC CTAACTCAGG AAATTGACTT TCTAAAAACG 
CTTTACATGG AGGAAATCCA GTTGCTGCAG TCGCACATCT CAGAGACGTC GGTCATTGTG 
AAGATGGACA ACAGCCGTGA CCTGAACCTT GATGGGATCA TTGCTGAGGT CAAGGCCCAG 
TATGAGGAGG TGGCCAGGCG CAGCCGGGCT GATGCTGAGG CCTGGTACCA GACCAAGTAT 
GAAGAGATGC AGGTGACAGC TGGCCAACAC TGTGACAACC TGCGCAACAT ACGGAACGAG 
ATCAACGAAC TGACCCGCCT GATCCAGAGG CTTAAGGCAG AGATTGAGCA CGCCAAGGCT 
CAGCGTGCCA AGTTGGAGGC TGCAGTGGCC GAGGCCGAGC AGCAGGGCGA GGCGACCCTC 
AGTGATGCCA AATGCAAGCT GGCAGATCTG GAGTGTGCCC TGCAGCAGGC CAAGCAGGAC 
ATGGCGCGGC AGCTGTGCGA GTACCAGGAG CTGATGAATG CCAAGCTGGG CCTGGACATC 
GAGATCGCCA CCTACAGGCG CCTGCTGGAG GGCGAGGAGA GCCGGCTCTG TGAAGGTGTT 
GGACCAGTAA ACATATCCGT CAGCAGCTCC CGGGGCGGCC TGGTGTGCGG GCCTGAGCCT 
TTGGTTGCCG GCTCCACCCT CTCCCGCGGC GGGGTCACCT TCTCAGGTAG CAGCAGCGTC 
TGTGCCACCA GTGGGGTCCT GGCTTCCTGT GGCCCCAGCC TGGGTGGAGC CCGGGTCGCC 
CCGGCCACTG GGGACCTGCT GAGCACTGGC ACAAGGAGTG GCTCCATGCT CATCAGCGAG 
GCCTGTGTCC CCAGCGTCCC CTGCCCCCTG CCCACCCAGG GGGGCTTCAG CAGCTGCAGC 
GGCGGCCGCA GCTCCAGCGT CCGCTTTGTG TCCACCACCA CCTCCTGCCG GACCAAGTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149034.2
CDS	68..1870
Translation	MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTSCRTKY

Target ORF information:

RefSeq Version	NM_033045.4
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 84 (KRT84), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033045.4

ORF Insert Sequence:

ATGTCTTGCC GCTCCTACCG AGTCAGCTCT GGTCACCGGG TGGGCAACTT CAGCTCTTGT 
TCAGCAATGA CACCACAGAA CCTGAATCGC TTCCGGGCCA ACTCTGTCTC CTGTTGGAGT 
GGGCCTGGAT TCCGGGGCCT TGGCAGCTTT GGTAGTCGGA GTGTCATCAC CTTTGGATCG 
TACTCACCCC GGATAGCAGC TGTAGGCTCT CGGCCCATCC ACTGTGGAGT CCGCTTTGGT 
GCTGGCTGTG GGATGGGTTT TGGTGATGGG AGAGGTGTTG GTCTGGGGCC TAGGGCTGAC 
AGCTGTGTTG GTCTGGGCTT TGGAGCTGGC AGTGGCATTG GCTATGGCTT TGGTGGCCCT 
GGCTTTGGTT ACAGAGTTGG AGGGGTTGGA GTCCCAGCAG CCCCATCTAT CACAGCTGTG 
ACTGTGAACA AGAGCCTACT GACCCCCCTC AACCTGGAGA TTGACCCCAA TGCCCAGAGG 
GTGAAGAAGG ATGAGAAGGA GCAAATCAAG ACCCTCAACA ACAAGTTTGC CTCCTTCATT 
GACAAGGTTC GGTTCCTAGA GCAGCAGAAT AAGCTCCTAG AGACCAAGTG GAGCTTCCTC 
CAAGAGCAGA AATGTATCAG GAGCAATCTG GAGCCACTCT TCGAGAGCTA CATCACCAAC 
CTGCGGAGGC AGTTGGAGGT GCTGGTCAGT GATCAGGCCC GGCTCCAGGC TGAGAGGAAC 
CACCTGCAGG ATGTCCTAGA GGGCTTCAAG AAGAAGTATG AAGAGGAAGT GGTATGTCGG 
GCCAATGCTG AGAATGAGTT TGTGGCTCTG AAGAAGGATG TGGATGCAGC TTTCATGAAC 
AAGTCTGATC TCGAGGCCAA CGTGGATACC CTAACTCAGG AAATTGACTT TCTAAAAACG 
CTTTACATGG AGGAAATCCA GTTGCTGCAG TCGCACATCT CAGAGACGTC GGTCATTGTG 
AAGATGGACA ACAGCCGTGA CCTGAACCTT GATGGGATCA TTGCTGAGGT CAAGGCCCAG 
TATGAGGAGG TGGCCAGGCG CAGCCGGGCT GATGCTGAGG CCTGGTACCA GACCAAGTAT 
GAAGAGATGC AGGTGACAGC TGGCCAACAC TGTGACAACC TGCGCAACAT ACGGAACGAG 
ATCAACGAAC TGACCCGCCT GATCCAGAGG CTTAAGGCAG AGATTGAGCA CGCCAAGGCT 
CAGCGTGCCA AGTTGGAGGC TGCAGTGGCC GAGGCCGAGC AGCAGGGCGA GGCGACCCTC 
AGTGATGCCA AATGCAAGCT GGCAGATCTG GAGTGTGCCC TGCAGCAGGC CAAGCAGGAC 
ATGGCGCGGC AGCTGTGCGA GTACCAGGAG CTGATGAATG CCAAGCTGGG CCTGGACATC 
GAGATCGCCA CCTACAGGCG CCTGCTGGAG GGCGAGGAGA GCCGGCTCTG TGAAGGTGTT 
GGACCAGTAA ACATATCCGT CAGCAGCTCC CGGGGCGGCC TGGTGTGCGG GCCTGAGCCT 
TTGGTTGCCG GCTCCACCCT CTCCCGCGGC GGGGTCACCT TCTCAGGTAG CAGCAGCGTC 
TGTGCCACCA GTGGGGTCCT GGCTTCCTGT GGCCCCAGCC TGGGTGGAGC CCGGGTCGCC 
CCGGCCACTG GGGACCTGCT GAGCACTGGC ACAAGGAGTG GCTCCATGCT CATCAGCGAG 
GCCTGTGTCC CCAGCGTCCC CTGCCCCCTG CCCACCCAGG GGGGCTTCAG CAGCTGCAGC 
GGCGGCCGCA GCTCCAGCGT CCGCTTTGTG TCCACCACCA CCTCCTGCCG GACCAAGTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRT84 ( NM_033045.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_149034.2 Homo sapiens keratin 84 (KRT84), mRNA.

Price & Availability↑

CloneID	OHu19075
Clone ID Related Accession (Same CDS sequence)	XM_011538335.2 , NM_033045.4 , NM_033045.3
Accession Version	NM_033045.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	keratin, type II cuticular Hb4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from BC069647.1. This sequence is a reference standard in the RefSeqGene project. On Mar 27, 2006 this sequence version replaced NM_033045.2. ##Evidence-Data-START## Transcript exon combination :: BC069647.1, AK314030.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 5' end.

ATGTCTTGCC GCTCCTACCG AGTCAGCTCT GGTCACCGGG TGGGCAACTT CAGCTCTTGT 
TCAGCAATGA CACCACAGAA CCTGAATCGC TTCCGGGCCA ACTCTGTCTC CTGTTGGAGT 
GGGCCTGGAT TCCGGGGCCT TGGCAGCTTT GGTAGTCGGA GTGTCATCAC CTTTGGATCG 
TACTCACCCC GGATAGCAGC TGTAGGCTCT CGGCCCATCC ACTGTGGAGT CCGCTTTGGT 
GCTGGCTGTG GGATGGGTTT TGGTGATGGG AGAGGTGTTG GTCTGGGGCC TAGGGCTGAC 
AGCTGTGTTG GTCTGGGCTT TGGAGCTGGC AGTGGCATTG GCTATGGCTT TGGTGGCCCT 
GGCTTTGGTT ACAGAGTTGG AGGGGTTGGA GTCCCAGCAG CCCCATCTAT CACAGCTGTG 
ACTGTGAACA AGAGCCTACT GACCCCCCTC AACCTGGAGA TTGACCCCAA TGCCCAGAGG 
GTGAAGAAGG ATGAGAAGGA GCAAATCAAG ACCCTCAACA ACAAGTTTGC CTCCTTCATT 
GACAAGGTTC GGTTCCTAGA GCAGCAGAAT AAGCTCCTAG AGACCAAGTG GAGCTTCCTC 
CAAGAGCAGA AATGTATCAG GAGCAATCTG GAGCCACTCT TCGAGAGCTA CATCACCAAC 
CTGCGGAGGC AGTTGGAGGT GCTGGTCAGT GATCAGGCCC GGCTCCAGGC TGAGAGGAAC 
CACCTGCAGG ATGTCCTAGA GGGCTTCAAG AAGAAGTATG AAGAGGAAGT GGTATGTCGG 
GCCAATGCTG AGAATGAGTT TGTGGCTCTG AAGAAGGATG TGGATGCAGC TTTCATGAAC 
AAGTCTGATC TCGAGGCCAA CGTGGATACC CTAACTCAGG AAATTGACTT TCTAAAAACG 
CTTTACATGG AGGAAATCCA GTTGCTGCAG TCGCACATCT CAGAGACGTC GGTCATTGTG 
AAGATGGACA ACAGCCGTGA CCTGAACCTT GATGGGATCA TTGCTGAGGT CAAGGCCCAG 
TATGAGGAGG TGGCCAGGCG CAGCCGGGCT GATGCTGAGG CCTGGTACCA GACCAAGTAT 
GAAGAGATGC AGGTGACAGC TGGCCAACAC TGTGACAACC TGCGCAACAT ACGGAACGAG 
ATCAACGAAC TGACCCGCCT GATCCAGAGG CTTAAGGCAG AGATTGAGCA CGCCAAGGCT 
CAGCGTGCCA AGTTGGAGGC TGCAGTGGCC GAGGCCGAGC AGCAGGGCGA GGCGACCCTC 
AGTGATGCCA AATGCAAGCT GGCAGATCTG GAGTGTGCCC TGCAGCAGGC CAAGCAGGAC 
ATGGCGCGGC AGCTGTGCGA GTACCAGGAG CTGATGAATG CCAAGCTGGG CCTGGACATC 
GAGATCGCCA CCTACAGGCG CCTGCTGGAG GGCGAGGAGA GCCGGCTCTG TGAAGGTGTT 
GGACCAGTAA ACATATCCGT CAGCAGCTCC CGGGGCGGCC TGGTGTGCGG GCCTGAGCCT 
TTGGTTGCCG GCTCCACCCT CTCCCGCGGC GGGGTCACCT TCTCAGGTAG CAGCAGCGTC 
TGTGCCACCA GTGGGGTCCT GGCTTCCTGT GGCCCCAGCC TGGGTGGAGC CCGGGTCGCC 
CCGGCCACTG GGGACCTGCT GAGCACTGGC ACAAGGAGTG GCTCCATGCT CATCAGCGAG 
GCCTGTGTCC CCAGCGTCCC CTGCCCCCTG CCCACCCAGG GGGGCTTCAG CAGCTGCAGC 
GGCGGCCGCA GCTCCAGCGT CCGCTTTGTG TCCACCACCA CCTCCTGCCG GACCAAGTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149034.2
CDS	49..1851
Translation	MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTSCRTKY

Target ORF information:

RefSeq Version	NM_033045.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 84 (KRT84), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033045.3

ORF Insert Sequence:

ATGTCTTGCC GCTCCTACCG AGTCAGCTCT GGTCACCGGG TGGGCAACTT CAGCTCTTGT 
TCAGCAATGA CACCACAGAA CCTGAATCGC TTCCGGGCCA ACTCTGTCTC CTGTTGGAGT 
GGGCCTGGAT TCCGGGGCCT TGGCAGCTTT GGTAGTCGGA GTGTCATCAC CTTTGGATCG 
TACTCACCCC GGATAGCAGC TGTAGGCTCT CGGCCCATCC ACTGTGGAGT CCGCTTTGGT 
GCTGGCTGTG GGATGGGTTT TGGTGATGGG AGAGGTGTTG GTCTGGGGCC TAGGGCTGAC 
AGCTGTGTTG GTCTGGGCTT TGGAGCTGGC AGTGGCATTG GCTATGGCTT TGGTGGCCCT 
GGCTTTGGTT ACAGAGTTGG AGGGGTTGGA GTCCCAGCAG CCCCATCTAT CACAGCTGTG 
ACTGTGAACA AGAGCCTACT GACCCCCCTC AACCTGGAGA TTGACCCCAA TGCCCAGAGG 
GTGAAGAAGG ATGAGAAGGA GCAAATCAAG ACCCTCAACA ACAAGTTTGC CTCCTTCATT 
GACAAGGTTC GGTTCCTAGA GCAGCAGAAT AAGCTCCTAG AGACCAAGTG GAGCTTCCTC 
CAAGAGCAGA AATGTATCAG GAGCAATCTG GAGCCACTCT TCGAGAGCTA CATCACCAAC 
CTGCGGAGGC AGTTGGAGGT GCTGGTCAGT GATCAGGCCC GGCTCCAGGC TGAGAGGAAC 
CACCTGCAGG ATGTCCTAGA GGGCTTCAAG AAGAAGTATG AAGAGGAAGT GGTATGTCGG 
GCCAATGCTG AGAATGAGTT TGTGGCTCTG AAGAAGGATG TGGATGCAGC TTTCATGAAC 
AAGTCTGATC TCGAGGCCAA CGTGGATACC CTAACTCAGG AAATTGACTT TCTAAAAACG 
CTTTACATGG AGGAAATCCA GTTGCTGCAG TCGCACATCT CAGAGACGTC GGTCATTGTG 
AAGATGGACA ACAGCCGTGA CCTGAACCTT GATGGGATCA TTGCTGAGGT CAAGGCCCAG 
TATGAGGAGG TGGCCAGGCG CAGCCGGGCT GATGCTGAGG CCTGGTACCA GACCAAGTAT 
GAAGAGATGC AGGTGACAGC TGGCCAACAC TGTGACAACC TGCGCAACAT ACGGAACGAG 
ATCAACGAAC TGACCCGCCT GATCCAGAGG CTTAAGGCAG AGATTGAGCA CGCCAAGGCT 
CAGCGTGCCA AGTTGGAGGC TGCAGTGGCC GAGGCCGAGC AGCAGGGCGA GGCGACCCTC 
AGTGATGCCA AATGCAAGCT GGCAGATCTG GAGTGTGCCC TGCAGCAGGC CAAGCAGGAC 
ATGGCGCGGC AGCTGTGCGA GTACCAGGAG CTGATGAATG CCAAGCTGGG CCTGGACATC 
GAGATCGCCA CCTACAGGCG CCTGCTGGAG GGCGAGGAGA GCCGGCTCTG TGAAGGTGTT 
GGACCAGTAA ACATATCCGT CAGCAGCTCC CGGGGCGGCC TGGTGTGCGG GCCTGAGCCT 
TTGGTTGCCG GCTCCACCCT CTCCCGCGGC GGGGTCACCT TCTCAGGTAG CAGCAGCGTC 
TGTGCCACCA GTGGGGTCCT GGCTTCCTGT GGCCCCAGCC TGGGTGGAGC CCGGGTCGCC 
CCGGCCACTG GGGACCTGCT GAGCACTGGC ACAAGGAGTG GCTCCATGCT CATCAGCGAG 
GCCTGTGTCC CCAGCGTCCC CTGCCCCCTG CCCACCCAGG GGGGCTTCAG CAGCTGCAGC 
GGCGGCCGCA GCTCCAGCGT CCGCTTTGTG TCCACCACCA CCTCCTGCCG GACCAAGTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRT84 ( XM_011538335.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011536637.1 Homo sapiens keratin 84 (KRT84), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu19075
Clone ID Related Accession (Same CDS sequence)	XM_011538335.2 , NM_033045.4 , NM_033045.3
Accession Version	XM_011538335.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	keratin, type II cuticular Hb4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011538335.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTTGCC GCTCCTACCG AGTCAGCTCT GGTCACCGGG TGGGCAACTT CAGCTCTTGT 
TCAGCAATGA CACCACAGAA CCTGAATCGC TTCCGGGCCA ACTCTGTCTC CTGTTGGAGT 
GGGCCTGGAT TCCGGGGCCT TGGCAGCTTT GGTAGTCGGA GTGTCATCAC CTTTGGATCG 
TACTCACCCC GGATAGCAGC TGTAGGCTCT CGGCCCATCC ACTGTGGAGT CCGCTTTGGT 
GCTGGCTGTG GGATGGGTTT TGGTGATGGG AGAGGTGTTG GTCTGGGGCC TAGGGCTGAC 
AGCTGTGTTG GTCTGGGCTT TGGAGCTGGC AGTGGCATTG GCTATGGCTT TGGTGGCCCT 
GGCTTTGGTT ACAGAGTTGG AGGGGTTGGA GTCCCAGCAG CCCCATCTAT CACAGCTGTG 
ACTGTGAACA AGAGCCTACT GACCCCCCTC AACCTGGAGA TTGACCCCAA TGCCCAGAGG 
GTGAAGAAGG ATGAGAAGGA GCAAATCAAG ACCCTCAACA ACAAGTTTGC CTCCTTCATT 
GACAAGGTTC GGTTCCTAGA GCAGCAGAAT AAGCTCCTAG AGACCAAGTG GAGCTTCCTC 
CAAGAGCAGA AATGTATCAG GAGCAATCTG GAGCCACTCT TCGAGAGCTA CATCACCAAC 
CTGCGGAGGC AGTTGGAGGT GCTGGTCAGT GATCAGGCCC GGCTCCAGGC TGAGAGGAAC 
CACCTGCAGG ATGTCCTAGA GGGCTTCAAG AAGAAGTATG AAGAGGAAGT GGTATGTCGG 
GCCAATGCTG AGAATGAGTT TGTGGCTCTG AAGAAGGATG TGGATGCAGC TTTCATGAAC 
AAGTCTGATC TCGAGGCCAA CGTGGATACC CTAACTCAGG AAATTGACTT TCTAAAAACG 
CTTTACATGG AGGAAATCCA GTTGCTGCAG TCGCACATCT CAGAGACGTC GGTCATTGTG 
AAGATGGACA ACAGCCGTGA CCTGAACCTT GATGGGATCA TTGCTGAGGT CAAGGCCCAG 
TATGAGGAGG TGGCCAGGCG CAGCCGGGCT GATGCTGAGG CCTGGTACCA GACCAAGTAT 
GAAGAGATGC AGGTGACAGC TGGCCAACAC TGTGACAACC TGCGCAACAT ACGGAACGAG 
ATCAACGAAC TGACCCGCCT GATCCAGAGG CTTAAGGCAG AGATTGAGCA CGCCAAGGCT 
CAGCGTGCCA AGTTGGAGGC TGCAGTGGCC GAGGCCGAGC AGCAGGGCGA GGCGACCCTC 
AGTGATGCCA AATGCAAGCT GGCAGATCTG GAGTGTGCCC TGCAGCAGGC CAAGCAGGAC 
ATGGCGCGGC AGCTGTGCGA GTACCAGGAG CTGATGAATG CCAAGCTGGG CCTGGACATC 
GAGATCGCCA CCTACAGGCG CCTGCTGGAG GGCGAGGAGA GCCGGCTCTG TGAAGGTGTT 
GGACCAGTAA ACATATCCGT CAGCAGCTCC CGGGGCGGCC TGGTGTGCGG GCCTGAGCCT 
TTGGTTGCCG GCTCCACCCT CTCCCGCGGC GGGGTCACCT TCTCAGGTAG CAGCAGCGTC 
TGTGCCACCA GTGGGGTCCT GGCTTCCTGT GGCCCCAGCC TGGGTGGAGC CCGGGTCGCC 
CCGGCCACTG GGGACCTGCT GAGCACTGGC ACAAGGAGTG GCTCCATGCT CATCAGCGAG 
GCCTGTGTCC CCAGCGTCCC CTGCCCCCTG CCCACCCAGG GGGGCTTCAG CAGCTGCAGC 
GGCGGCCGCA GCTCCAGCGT CCGCTTTGTG TCCACCACCA CCTCCTGCCG GACCAAGTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011536637.1
CDS	164..1966
Translation	MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTSCRTKY

Target ORF information:

RefSeq Version	XM_011538335.2
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 84 (KRT84), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538335.2

ORF Insert Sequence:

ATGTCTTGCC GCTCCTACCG AGTCAGCTCT GGTCACCGGG TGGGCAACTT CAGCTCTTGT 
TCAGCAATGA CACCACAGAA CCTGAATCGC TTCCGGGCCA ACTCTGTCTC CTGTTGGAGT 
GGGCCTGGAT TCCGGGGCCT TGGCAGCTTT GGTAGTCGGA GTGTCATCAC CTTTGGATCG 
TACTCACCCC GGATAGCAGC TGTAGGCTCT CGGCCCATCC ACTGTGGAGT CCGCTTTGGT 
GCTGGCTGTG GGATGGGTTT TGGTGATGGG AGAGGTGTTG GTCTGGGGCC TAGGGCTGAC 
AGCTGTGTTG GTCTGGGCTT TGGAGCTGGC AGTGGCATTG GCTATGGCTT TGGTGGCCCT 
GGCTTTGGTT ACAGAGTTGG AGGGGTTGGA GTCCCAGCAG CCCCATCTAT CACAGCTGTG 
ACTGTGAACA AGAGCCTACT GACCCCCCTC AACCTGGAGA TTGACCCCAA TGCCCAGAGG 
GTGAAGAAGG ATGAGAAGGA GCAAATCAAG ACCCTCAACA ACAAGTTTGC CTCCTTCATT 
GACAAGGTTC GGTTCCTAGA GCAGCAGAAT AAGCTCCTAG AGACCAAGTG GAGCTTCCTC 
CAAGAGCAGA AATGTATCAG GAGCAATCTG GAGCCACTCT TCGAGAGCTA CATCACCAAC 
CTGCGGAGGC AGTTGGAGGT GCTGGTCAGT GATCAGGCCC GGCTCCAGGC TGAGAGGAAC 
CACCTGCAGG ATGTCCTAGA GGGCTTCAAG AAGAAGTATG AAGAGGAAGT GGTATGTCGG 
GCCAATGCTG AGAATGAGTT TGTGGCTCTG AAGAAGGATG TGGATGCAGC TTTCATGAAC 
AAGTCTGATC TCGAGGCCAA CGTGGATACC CTAACTCAGG AAATTGACTT TCTAAAAACG 
CTTTACATGG AGGAAATCCA GTTGCTGCAG TCGCACATCT CAGAGACGTC GGTCATTGTG 
AAGATGGACA ACAGCCGTGA CCTGAACCTT GATGGGATCA TTGCTGAGGT CAAGGCCCAG 
TATGAGGAGG TGGCCAGGCG CAGCCGGGCT GATGCTGAGG CCTGGTACCA GACCAAGTAT 
GAAGAGATGC AGGTGACAGC TGGCCAACAC TGTGACAACC TGCGCAACAT ACGGAACGAG 
ATCAACGAAC TGACCCGCCT GATCCAGAGG CTTAAGGCAG AGATTGAGCA CGCCAAGGCT 
CAGCGTGCCA AGTTGGAGGC TGCAGTGGCC GAGGCCGAGC AGCAGGGCGA GGCGACCCTC 
AGTGATGCCA AATGCAAGCT GGCAGATCTG GAGTGTGCCC TGCAGCAGGC CAAGCAGGAC 
ATGGCGCGGC AGCTGTGCGA GTACCAGGAG CTGATGAATG CCAAGCTGGG CCTGGACATC 
GAGATCGCCA CCTACAGGCG CCTGCTGGAG GGCGAGGAGA GCCGGCTCTG TGAAGGTGTT 
GGACCAGTAA ACATATCCGT CAGCAGCTCC CGGGGCGGCC TGGTGTGCGG GCCTGAGCCT 
TTGGTTGCCG GCTCCACCCT CTCCCGCGGC GGGGTCACCT TCTCAGGTAG CAGCAGCGTC 
TGTGCCACCA GTGGGGTCCT GGCTTCCTGT GGCCCCAGCC TGGGTGGAGC CCGGGTCGCC 
CCGGCCACTG GGGACCTGCT GAGCACTGGC ACAAGGAGTG GCTCCATGCT CATCAGCGAG 
GCCTGTGTCC CCAGCGTCCC CTGCCCCCTG CCCACCCAGG GGGGCTTCAG CAGCTGCAGC 
GGCGGCCGCA GCTCCAGCGT CCGCTTTGTG TCCACCACCA CCTCCTGCCG GACCAAGTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

New consensus nomenclature for mammalian keratins.
The Journal of cell biology174(2)169-74(2006 Jul)
Schweizer J,Bowden PE,Coulombe PA,Langbein L,Lane EB,Magin TM,Maltais L,Omary MB,Parry DA,Rogers MA,Wright MW

Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13.
The Journal of investigative dermatology124(3)536-44(2005 Mar)
Rogers MA,Edler L,Winter H,Langbein L,Beckmann I,Schweizer J

Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.
The Journal of investigative dermatology114(3)464-72(2000 Mar)
Rogers MA,Winter H,Langbein L,Wolf C,Schweizer J

The complement of native alpha-keratin polypeptides of hair-forming cells: a subset of eight polypeptides that differ from epithelial cytokeratins.
Differentiation; research in biological diversity32(2)101-19(1986)
Heid HW,Werner E,Franke WW

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KRT84 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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