KRT81 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRT81
Entrez Gene ID	3887
Full Name	keratin 81
Synonyms	HB1,Hb-1,KRTHB1,MLN137,ghHkb1,hHAKB2-1
General protein information	Preferred Names keratin 81 Names keratin, type II cuticular Hb1 K81 MLN 137 ghHb1 hair keratin K2.9 hard keratin, type II, 1 keratin 81, type II keratin, hair, basic, 1 metastatic lymph node 137 gene protein type II hair keratin Hb1 type-II keratin Kb21
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.13
Summary	The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008].
Disorder MIM:	602153
Disorder Html:	Monilethrix, 158000 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002281.4	NP_002272.2	keratin, type II cuticular Hb1
NM_002281.3	NP_002272.2	keratin, type II cuticular Hb1

Pathways from BioSystems

Homologies

	KRT81	XP_001093214.1
Mus musculus (house mouse)	Krt81	NP_001159629.1
Rattus norvegicus (Norway rat)	Krt81	NP_001008814.1
Canis lupus familiaris (dog)	KRT81	XP_543657.2
Canis lupus familiaris (dog)	LOC486529	XP_850166.2
Bos taurus (cattle)	KRT81	NP_001069674.1
Pan troglodytes (chimpanzee)	KRT81	XP_003313755.1
Homo sapiens (human)	KRT81	NP_002272.2

Gene Ontology
Bibliography

Related articles in PubMed

Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response.
Muckenhuber A, Berger AK, Schlitter AM, Steiger K, Konukiewitz B, Trumpp A, Eils R, Werner J, Friess H, Esposito I, Kl?ppel G, Ceyhan GO, Jesinghaus M, Denkert C, Bahra M, Stenzinger A, Sprick MR, J?ger D, Springfeld C, Weichert W
Clinical cancer research : an official journal of the American Association for Cancer Research24(2)351-359(2018 Jan)

Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.
Nanashima N, Horie K, Yamada T, Shimizu T, Tsuchida S
Oncology reports37(5)2964-2970(2017 May)

A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer.
Lee SY, Choi JE, Jeon HS, Hong MJ, Choi YY, Kang HG, Yoo SS, Lee EB, Jeong JY, Lee WK, Lee J, Cha SI, Kim CH, Kim YT, Jheon S, Son JW, Park JY
Annals of oncology : official journal of the European Society for Medical Oncology26(6)1142-8(2015 Jun)

Novel KRT83 and KRT86 mutations associated with monilethrix.
van Steensel M, Vreeburg M, Urbina MT, L?pez P, Morice-Picard F, van Geel M
Experimental dermatology24(3)222-4(2015 Mar)

A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma.
Xie Y, Diao L, Zhang L, Liu C, Xu Z, Liu S
Gene539(2)198-202(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results show that full size KRT81 is expressed in normal breast epithelial cells and breast cancer cells, and indicate that KRT81 contributes to the migration and invasion of breast cancer cells.
Title: Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.

The analysis of the KRT81rs3660G>C polymorphism may be useful to identify non-small cell lung cancer patients at high risk of a poor disease outcome.
Title: A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer.

Novel mutations causing monilethrix are reported in KRT81, KRT83, and KRT86.
Title: Novel KRT83 and KRT86 mutations associated with monilethrix.

MiRNA-related single nucleotide polymorphism sites of KRT81 is associated with non-Hodgkin's lymphoma.
Title: A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma.

Overall survival was significantly longer in multiple myeloma patients with KRT81 rs3660 C/C variant
Title: Impact of MiRSNPs on survival and progression in patients with multiple myeloma undergoing autologous stem cell transplantation.

The following KRT81 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRT81 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24118	NM_002281.4 Latest version!	Homo sapiens keratin 81 (KRT81), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu24118	NM_002281.3	Homo sapiens keratin 81 (KRT81), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRT81 ( NM_002281.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002272.2 Homo sapiens keratin 81 (KRT81), mRNA.

Price & Availability↑

CloneID	OHu24118
Clone ID Related Accession (Same CDS sequence)	NM_002281.4 , NM_002281.3
Accession Version	NM_002281.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1518bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	keratin, type II cuticular Hb1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC121757.8 and X81420.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_002281.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the bull length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X81420.1, BC117465.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159931 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000327741.9/ ENSP00000369349.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACCTGCG GATCAGGATT TGGTGGGCGC GCCTTCAGCT GCATCTCGGC CTGCGGGCCG 
CGGCCCGGCC GCTGCTGCAT CACCGCCGCC CCCTACCGTG GCATCTCCTG CTACCGCGGC 
CTCACCGGGG GCTTCGGCAG CCACAGCGTG TGCGGAGGCT TTCGGGCCGG CTCCTGCGGA 
CGCAGCTTCG GCTACCGCTC CGGGGGCGTG TGCGGGCCCA GTCCCCCATG CATCACCACC 
GTGTCGGTCA ACGAGAGCCT CCTCACGCCC CTCAACCTGG AGATCGACCC CAACGCGCAG 
TGCGTGAAGC AGGAGGAGAA GGAGCAGATC AAGTCCCTCA ACAGCAGGTT CGCGGCCTTC 
ATCGACAAGG TGCGCTTCCT GGAGCAGCAG AACAAACTGC TGGAGACAAA GCTGCAGTTC 
TACCAGAACC GCGAGTGTTG CCAGAGCAAC CTGGAGCCCC TGTTTGAGGG CTACATCGAG 
ACTCTGCGGC GGGAGGCCGA GTGCGTGGAG GCCGACAGCG GGAGGCTGGC CTCAGAGCTT 
AACCACGTGC AGGAGGTGCT GGAGGGCTAC AAGAAGAAGT ATGAGGAGGA GGTTTCTCTG 
AGAGCAACAG CTGAGAACGA GTTTGTGGCT CTGAAGAAGG ATGTGGACTG CGCCTACCTC 
CGCAAGTCAG ACCTGGAGGC CAACGTGGAG GCCCTGATCC AGGAGATCGA CTTCCTGAGG 
CGGCTGTATG AGGAGGAGAT CCTCATTCTC CAGTCGCACA TCTCAGACAC CTCCGTGGTT 
GTCAAGCTGG ACAACAGCCG GGACCTGAAC ATGGACTGCA TCATTGCCGA GATTAAGGCA 
CAGTATGACG ACATTGTCAC CCGCAGCCGG GCCGAGGCCG AGTCCTGGTA CCGCAGCAAG 
TGTGAGGAGA TGAAGGCCAC GGTGATCAGG CACGGGGAGA CCCTGCGCCG CACCAAGGAG 
GAGATCAATG AGCTGAACCG CATGATCCAA AGGCTGACGG CCGAGGTGGA GAATGCCAAG 
TGCCAGAACT CCAAGCTGGA GGCCGCGGTG GCCCAGTCTG AGCAGCAGGG TGAGGCGGCC 
CTCAGTGATG CCCGCTGCAA GCTGGCCGAG CTGGAGGGCG CCCTGCAGAA GGCCAAGCAG 
GACATGGCCT GCCTGATCAG GGAGTACCAG GAGGTGATGA ACTCCAAGCT GGGCCTGGAC 
ATCGAGATCG CCACCTACAG GCGCCTGCTG GAGGGCGAGG AGCAGAGGCT ATGTGAAGGC 
ATTGGGGCTG TGAATGTCTG TGTCAGCAGC TCCCGGGGCG GGGTCGTGTG CGGGGACCTC 
TGCGTGTCAG GCTCCCGGCC AGTGACTGGC AGTGTCTGCA GCGCTCCGTG CAACGGGAAC 
GTGGCGGTGA GCACCGGCCT GTGTGCGCCC TGCGGCCAAT TGAACACCAC CTGCGGAGGG 
GGTTCCTGCG GCGTGGGCTC CTGTGGTATC AGCTCCCTGG GTGTGGGGTC TTGCGGCAGC 
AGCTGCCGGA AATGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002272.2
CDS	70..1587
Translation	MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRKC

Target ORF information:

RefSeq Version	NM_002281.4
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 81 (KRT81), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002281.4

ORF Insert Sequence:

ATGACCTGCG GATCAGGATT TGGTGGGCGC GCCTTCAGCT GCATCTCGGC CTGCGGGCCG 
CGGCCCGGCC GCTGCTGCAT CACCGCCGCC CCCTACCGTG GCATCTCCTG CTACCGCGGC 
CTCACCGGGG GCTTCGGCAG CCACAGCGTG TGCGGAGGCT TTCGGGCCGG CTCCTGCGGA 
CGCAGCTTCG GCTACCGCTC CGGGGGCGTG TGCGGGCCCA GTCCCCCATG CATCACCACC 
GTGTCGGTCA ACGAGAGCCT CCTCACGCCC CTCAACCTGG AGATCGACCC CAACGCGCAG 
TGCGTGAAGC AGGAGGAGAA GGAGCAGATC AAGTCCCTCA ACAGCAGGTT CGCGGCCTTC 
ATCGACAAGG TGCGCTTCCT GGAGCAGCAG AACAAACTGC TGGAGACAAA GCTGCAGTTC 
TACCAGAACC GCGAGTGTTG CCAGAGCAAC CTGGAGCCCC TGTTTGAGGG CTACATCGAG 
ACTCTGCGGC GGGAGGCCGA GTGCGTGGAG GCCGACAGCG GGAGGCTGGC CTCAGAGCTT 
AACCACGTGC AGGAGGTGCT GGAGGGCTAC AAGAAGAAGT ATGAGGAGGA GGTTTCTCTG 
AGAGCAACAG CTGAGAACGA GTTTGTGGCT CTGAAGAAGG ATGTGGACTG CGCCTACCTC 
CGCAAGTCAG ACCTGGAGGC CAACGTGGAG GCCCTGATCC AGGAGATCGA CTTCCTGAGG 
CGGCTGTATG AGGAGGAGAT CCTCATTCTC CAGTCGCACA TCTCAGACAC CTCCGTGGTT 
GTCAAGCTGG ACAACAGCCG GGACCTGAAC ATGGACTGCA TCATTGCCGA GATTAAGGCA 
CAGTATGACG ACATTGTCAC CCGCAGCCGG GCCGAGGCCG AGTCCTGGTA CCGCAGCAAG 
TGTGAGGAGA TGAAGGCCAC GGTGATCAGG CACGGGGAGA CCCTGCGCCG CACCAAGGAG 
GAGATCAATG AGCTGAACCG CATGATCCAA AGGCTGACGG CCGAGGTGGA GAATGCCAAG 
TGCCAGAACT CCAAGCTGGA GGCCGCGGTG GCCCAGTCTG AGCAGCAGGG TGAGGCGGCC 
CTCAGTGATG CCCGCTGCAA GCTGGCCGAG CTGGAGGGCG CCCTGCAGAA GGCCAAGCAG 
GACATGGCCT GCCTGATCAG GGAGTACCAG GAGGTGATGA ACTCCAAGCT GGGCCTGGAC 
ATCGAGATCG CCACCTACAG GCGCCTGCTG GAGGGCGAGG AGCAGAGGCT ATGTGAAGGC 
ATTGGGGCTG TGAATGTCTG TGTCAGCAGC TCCCGGGGCG GGGTCGTGTG CGGGGACCTC 
TGCGTGTCAG GCTCCCGGCC AGTGACTGGC AGTGTCTGCA GCGCTCCGTG CAACGGGAAC 
GTGGCGGTGA GCACCGGCCT GTGTGCGCCC TGCGGCCAAT TGAACACCAC CTGCGGAGGG 
GGTTCCTGCG GCGTGGGCTC CTGTGGTATC AGCTCCCTGG GTGTGGGGTC TTGCGGCAGC 
AGCTGCCGGA AATGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRT81 ( NM_002281.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002272.2 Homo sapiens keratin 81 (KRT81), mRNA.

Price & Availability↑

CloneID	OHu24118
Clone ID Related Accession (Same CDS sequence)	NM_002281.4 , NM_002281.3
Accession Version	NM_002281.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1518bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	keratin, type II cuticular Hb1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC121757.8 and X81420.1. This sequence is a reference standard in the RefSeqGene project. On Mar 12, 2008 this sequence version replaced NM_002281.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the bull length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X81420.1, BC117467.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159931 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGACCTGCG GATCAGGATT TGGTGGGCGC GCCTTCAGCT GCATCTCGGC CTGCGGGCCG 
CGGCCCGGCC GCTGCTGCAT CACCGCCGCC CCCTACCGTG GCATCTCCTG CTACCGCGGC 
CTCACCGGGG GCTTCGGCAG CCACAGCGTG TGCGGAGGCT TTCGGGCCGG CTCCTGCGGA 
CGCAGCTTCG GCTACCGCTC CGGGGGCGTG TGCGGGCCCA GTCCCCCATG CATCACCACC 
GTGTCGGTCA ACGAGAGCCT CCTCACGCCC CTCAACCTGG AGATCGACCC CAACGCGCAG 
TGCGTGAAGC AGGAGGAGAA GGAGCAGATC AAGTCCCTCA ACAGCAGGTT CGCGGCCTTC 
ATCGACAAGG TGCGCTTCCT GGAGCAGCAG AACAAACTGC TGGAGACAAA GCTGCAGTTC 
TACCAGAACC GCGAGTGTTG CCAGAGCAAC CTGGAGCCCC TGTTTGAGGG CTACATCGAG 
ACTCTGCGGC GGGAGGCCGA GTGCGTGGAG GCCGACAGCG GGAGGCTGGC CTCAGAGCTT 
AACCACGTGC AGGAGGTGCT GGAGGGCTAC AAGAAGAAGT ATGAGGAGGA GGTTTCTCTG 
AGAGCAACAG CTGAGAACGA GTTTGTGGCT CTGAAGAAGG ATGTGGACTG CGCCTACCTC 
CGCAAGTCAG ACCTGGAGGC CAACGTGGAG GCCCTGATCC AGGAGATCGA CTTCCTGAGG 
CGGCTGTATG AGGAGGAGAT CCTCATTCTC CAGTCGCACA TCTCAGACAC CTCCGTGGTT 
GTCAAGCTGG ACAACAGCCG GGACCTGAAC ATGGACTGCA TCATTGCCGA GATTAAGGCA 
CAGTATGACG ACATTGTCAC CCGCAGCCGG GCCGAGGCCG AGTCCTGGTA CCGCAGCAAG 
TGTGAGGAGA TGAAGGCCAC GGTGATCAGG CACGGGGAGA CCCTGCGCCG CACCAAGGAG 
GAGATCAATG AGCTGAACCG CATGATCCAA AGGCTGACGG CCGAGGTGGA GAATGCCAAG 
TGCCAGAACT CCAAGCTGGA GGCCGCGGTG GCCCAGTCTG AGCAGCAGGG TGAGGCGGCC 
CTCAGTGATG CCCGCTGCAA GCTGGCCGAG CTGGAGGGCG CCCTGCAGAA GGCCAAGCAG 
GACATGGCCT GCCTGATCAG GGAGTACCAG GAGGTGATGA ACTCCAAGCT GGGCCTGGAC 
ATCGAGATCG CCACCTACAG GCGCCTGCTG GAGGGCGAGG AGCAGAGGCT ATGTGAAGGC 
ATTGGGGCTG TGAATGTCTG TGTCAGCAGC TCCCGGGGCG GGGTCGTGTG CGGGGACCTC 
TGCGTGTCAG GCTCCCGGCC AGTGACTGGC AGTGTCTGCA GCGCTCCGTG CAACGGGAAC 
GTGGCGGTGA GCACCGGCCT GTGTGCGCCC TGCGGCCAAT TGAACACCAC CTGCGGAGGG 
GGTTCCTGCG GCGTGGGCTC CTGTGGTATC AGCTCCCTGG GTGTGGGGTC TTGCGGCAGC 
AGCTGCCGGA AATGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002272.2
CDS	51..1568
Translation	MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRKC

Target ORF information:

RefSeq Version	NM_002281.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 81 (KRT81), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002281.3

ORF Insert Sequence:

ATGACCTGCG GATCAGGATT TGGTGGGCGC GCCTTCAGCT GCATCTCGGC CTGCGGGCCG 
CGGCCCGGCC GCTGCTGCAT CACCGCCGCC CCCTACCGTG GCATCTCCTG CTACCGCGGC 
CTCACCGGGG GCTTCGGCAG CCACAGCGTG TGCGGAGGCT TTCGGGCCGG CTCCTGCGGA 
CGCAGCTTCG GCTACCGCTC CGGGGGCGTG TGCGGGCCCA GTCCCCCATG CATCACCACC 
GTGTCGGTCA ACGAGAGCCT CCTCACGCCC CTCAACCTGG AGATCGACCC CAACGCGCAG 
TGCGTGAAGC AGGAGGAGAA GGAGCAGATC AAGTCCCTCA ACAGCAGGTT CGCGGCCTTC 
ATCGACAAGG TGCGCTTCCT GGAGCAGCAG AACAAACTGC TGGAGACAAA GCTGCAGTTC 
TACCAGAACC GCGAGTGTTG CCAGAGCAAC CTGGAGCCCC TGTTTGAGGG CTACATCGAG 
ACTCTGCGGC GGGAGGCCGA GTGCGTGGAG GCCGACAGCG GGAGGCTGGC CTCAGAGCTT 
AACCACGTGC AGGAGGTGCT GGAGGGCTAC AAGAAGAAGT ATGAGGAGGA GGTTTCTCTG 
AGAGCAACAG CTGAGAACGA GTTTGTGGCT CTGAAGAAGG ATGTGGACTG CGCCTACCTC 
CGCAAGTCAG ACCTGGAGGC CAACGTGGAG GCCCTGATCC AGGAGATCGA CTTCCTGAGG 
CGGCTGTATG AGGAGGAGAT CCTCATTCTC CAGTCGCACA TCTCAGACAC CTCCGTGGTT 
GTCAAGCTGG ACAACAGCCG GGACCTGAAC ATGGACTGCA TCATTGCCGA GATTAAGGCA 
CAGTATGACG ACATTGTCAC CCGCAGCCGG GCCGAGGCCG AGTCCTGGTA CCGCAGCAAG 
TGTGAGGAGA TGAAGGCCAC GGTGATCAGG CACGGGGAGA CCCTGCGCCG CACCAAGGAG 
GAGATCAATG AGCTGAACCG CATGATCCAA AGGCTGACGG CCGAGGTGGA GAATGCCAAG 
TGCCAGAACT CCAAGCTGGA GGCCGCGGTG GCCCAGTCTG AGCAGCAGGG TGAGGCGGCC 
CTCAGTGATG CCCGCTGCAA GCTGGCCGAG CTGGAGGGCG CCCTGCAGAA GGCCAAGCAG 
GACATGGCCT GCCTGATCAG GGAGTACCAG GAGGTGATGA ACTCCAAGCT GGGCCTGGAC 
ATCGAGATCG CCACCTACAG GCGCCTGCTG GAGGGCGAGG AGCAGAGGCT ATGTGAAGGC 
ATTGGGGCTG TGAATGTCTG TGTCAGCAGC TCCCGGGGCG GGGTCGTGTG CGGGGACCTC 
TGCGTGTCAG GCTCCCGGCC AGTGACTGGC AGTGTCTGCA GCGCTCCGTG CAACGGGAAC 
GTGGCGGTGA GCACCGGCCT GTGTGCGCCC TGCGGCCAAT TGAACACCAC CTGCGGAGGG 
GGTTCCTGCG GCGTGGGCTC CTGTGGTATC AGCTCCCTGG GTGTGGGGTC TTGCGGCAGC 
AGCTGCCGGA AATGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response.
Clinical cancer research : an official journal of the American Association for Cancer Research24(2)351-359(2018 Jan)
Muckenhuber A,Berger AK,Schlitter AM,Steiger K,Konukiewitz B,Trumpp A,Eils R,Werner J,Friess H,Esposito I,Kl?ppel G,Ceyhan GO,Jesinghaus M,Denkert C,Bahra M,Stenzinger A,Sprick MR,J?ger D,Springfeld C,Weichert W

Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness.
Oncology reports37(5)2964-2970(2017 May)
Nanashima N,Horie K,Yamada T,Shimizu T,Tsuchida S

A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology26(6)1142-8(2015 Jun)
Lee SY,Choi JE,Jeon HS,Hong MJ,Choi YY,Kang HG,Yoo SS,Lee EB,Jeong JY,Lee WK,Lee J,Cha SI,Kim CH,Kim YT,Jheon S,Son JW,Park JY

Novel KRT83 and KRT86 mutations associated with monilethrix.
Experimental dermatology24(3)222-4(2015 Mar)
van Steensel M,Vreeburg M,Urbina MT,L?pez P,Morice-Picard F,van Geel M

A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma.
Gene539(2)198-202(2014 Apr)
Xie Y,Diao L,Zhang L,Liu C,Xu Z,Liu S

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KRT81 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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