TBPL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TBPL2
Entrez Gene ID	387332
Full Name	TATA-box binding protein like 2
Synonyms	TBP2,TRF3
General protein information	Preferred Names TATA-box binding protein like 2 Names TATA box-binding protein-like protein 2 TATA box-binding protein-related factor 3 TBP-like protein 2 TBP-related factor 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q22.3
Disorder MIM:	608964

mRNA and Protein(s)

mRNA	Protein	Name
NM_199047.2	NP_950248.1	TATA box-binding protein-like protein 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TBPL2	XP_003952543.1
Bos taurus (cattle)	TBPL2	XP_002690959.2
Oryza sativa (rice)	Os03g0657000	NP_001050812.1
Arabidopsis thaliana (thale cress)	TBP2	NP_849812.1
Arabidopsis thaliana (thale cress)	TBP1	NP_187953.1
Mus musculus (house mouse)	Tbpl2	NP_951014.1
Gallus gallus (chicken)	TBPL2	NP_001092323.1
Xenopus tropicalis (tropical clawed frog)	tbpl2	NP_001017309.1
Homo sapiens (human)	TBPL2	NP_950248.1
Canis lupus familiaris (dog)	TBPL2	XP_005623974.1
Rattus norvegicus (Norway rat)	Tbpl2	NP_001092831.1
Oryza sativa (rice)	Os12g0580300	NP_001067128.1
	LOC697371	XP_001088740.1
Danio rerio (zebrafish)	tbpl2	NP_999961.1

Gene Ontology
Bibliography

Related articles in PubMed

TBP2 gene may not be associated with primary ovarian insufficiency.
Wang C, Cao J, Xing Y, Pu D, Liu J, Wu J
Climacteric : the journal of the International Menopause Society19(6)565-567(2016 Dec)

Switching of the core transcription machinery during myogenesis.
Deato MD, Tjian R
Genes & development21(17)2137-49(2007 Sep)

Genomics, evolution, and expression of TBPL2, a member of the TBP family.
Di Pietro C, Ragusa M, Duro L, Guglielmino MR, Barbagallo D, Carnemolla A, Lagan? A, Buffa P, Angelica R, Rinaldi A, Calafato MS, Milicia I, Caserta C, Giugno R, Pulvirenti A, Giunta V, Rapisarda A, Di Pietro V, Grillo A, Messina A, Ferro A, Grzeschik KH, Purrello M
DNA and cell biology26(6)369-85(2007 Jun)

TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed.
Persengiev SP, Zhu X, Dixit BL, Maston GA, Kittler EL, Green MR
Proceedings of the National Academy of Sciences of the United States of America100(25)14887-91(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

study indicates that the TBP2 gene is not responsible for idiopathic primary ovarian insufficiency in the Chinese Han population
Title: TBP2 gene may not be associated with primary ovarian insufficiency.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Here we report that differentiation of myoblast to myotubes involves the disruption of the canonical holo-TFIID and replacement by a novel TRF3/TAF3 (TBP-related factor 3/TATA-binding protein-associated factor 3) complex.
Title: Switching of the core transcription machinery during myogenesis.

TRF3 is a nuclear protein that is present in all human and mouse tissues and cell lines examined
Title: TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed.

The following TBPL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TBPL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu30400	NM_199047.2 Latest version!	Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TBPL2 ( NM_199047.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_950248.1 Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.

Price & Availability↑

CloneID	OHu30400
Clone ID Related Accession (Same CDS sequence)	NM_199047.2
Accession Version	NM_199047.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1128bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	TATA box-binding protein-like protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY457923.1 and AL356801.5. On Apr 25, 2006 this sequence version replaced NM_199047.1. ##Evidence-Data-START## Transcript exon combination :: AY457923.1, DQ448593.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCCTCTG CGCCCTGGCC GGAGCGGGTT CCGAGGCTGC TCGCTCCGCG CTTACCCTCT 
TACCCGCCCC CACCCCCAAC AGTGGGATTA CGGTCCATGG AGCAGGAGGA GACCTACCTG 
GAGCTCTACC TGGACCAGTG CGCCGCTCAG GATGGCCTTG CCCCACCCAG GTCTCCCCTG 
TTCAGCCCAG TTGTACCTTA TGATATGTAC ATACTGAATG CATCCAATCC GGATACTGCA 
TTTAATTCGA ACCCTGAAGT CAAAGAAACA TCTGGTGATT TCTCATCTGT GGATCTTAGC 
TTCCTACCAG ATGAAGTTAC CCAGGAAAAT AAAGACCAGC CTGTCATTAG CAAACACGAA 
ACTGAAGAAA ATTCTGAAAG CCAAAGTCCA CAAAGTAGGT TGCCATCACC CAGCGAACAG 
GACGTTGGGC TGGGCTTAAA CAGCAGCAGT TTGTCAAATT CCCATTCACA GCTGCACCCT 
GGTGATACTG ACTCAGTCCA GCCCTCTCCT GAGAAACCAA ACTCCGACTC CTTGTCTCTG 
GCATCCATAA CTCCCATGAC ACCAATGACC CCTATTTCAG AATGTTGTGG AATTGTACCT 
CAACTACAGA ATATAGTTTC CACTGTAAAC CTGGCCTGTA AGTTGGATCT GAAGAAAATA 
GCTTTGCATG CAAAAAATGC AGAATATAAC CCAAAGAGGT TTGCTGCTGT CATAATGAGG 
ATCCGAGAGC CCAGGACAAC AGCCCTTATA TTTAGCTCTG GGAAGATGGT CTGCACGGGA 
GCCAAAAGTG AAGAGCAGTC TCGACTTGCA GCAAGAAAAT ATGCTCGTGT GGTGCAGAAG 
CTTGGGTTCC CTGCCAGATT CCTCGATTTT AAAATTCAGA ACATGGTTGG AAGCTGTGAT 
GTGAGATTTC CCATCAGGCT GGAAGGTTTG GTGCTAACCC ATCAGCAGTT CAGTAGTTAC 
GAGCCTGAAC TGTTTCCTGG TCTTATTTAT AGAATGGTAA AACCACGAAT TGTGTTGCTT 
ATCTTTGTAT CTGGAAAAGT TGTGTTGACA GGTGCCAAAG AACGTTCTGA GATCTATGAA 
GCATTTGAAA ACATCTATCC TATTCTAAAA GGTTTTAAAA AAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_950248.1
CDS	1..1128
Translation	MASAPWPERVPRLLAPRLPSYPPPPPTVGLRSMEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHETEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKKA

Target ORF information:

RefSeq Version	NM_199047.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199047.2

ORF Insert Sequence:

ATGGCCTCTG CGCCCTGGCC GGAGCGGGTT CCGAGGCTGC TCGCTCCGCG CTTACCCTCT 
TACCCGCCCC CACCCCCAAC AGTGGGATTA CGGTCCATGG AGCAGGAGGA GACCTACCTG 
GAGCTCTACC TGGACCAGTG CGCCGCTCAG GATGGCCTTG CCCCACCCAG GTCTCCCCTG 
TTCAGCCCAG TTGTACCTTA TGATATGTAC ATACTGAATG CATCCAATCC GGATACTGCA 
TTTAATTCGA ACCCTGAAGT CAAAGAAACA TCTGGTGATT TCTCATCTGT GGATCTTAGC 
TTCCTACCAG ATGAAGTTAC CCAGGAAAAT AAAGACCAGC CTGTCATTAG CAAACACGAA 
ACTGAAGAAA ATTCTGAAAG CCAAAGTCCA CAAAGTAGGT TGCCATCACC CAGCGAACAG 
GACGTTGGGC TGGGCTTAAA CAGCAGCAGT TTGTCAAATT CCCATTCACA GCTGCACCCT 
GGTGATACTG ACTCAGTCCA GCCCTCTCCT GAGAAACCAA ACTCCGACTC CTTGTCTCTG 
GCATCCATAA CTCCCATGAC ACCAATGACC CCTATTTCAG AATGTTGTGG AATTGTACCT 
CAACTACAGA ATATAGTTTC CACTGTAAAC CTGGCCTGTA AGTTGGATCT GAAGAAAATA 
GCTTTGCATG CAAAAAATGC AGAATATAAC CCAAAGAGGT TTGCTGCTGT CATAATGAGG 
ATCCGAGAGC CCAGGACAAC AGCCCTTATA TTTAGCTCTG GGAAGATGGT CTGCACGGGA 
GCCAAAAGTG AAGAGCAGTC TCGACTTGCA GCAAGAAAAT ATGCTCGTGT GGTGCAGAAG 
CTTGGGTTCC CTGCCAGATT CCTCGATTTT AAAATTCAGA ACATGGTTGG AAGCTGTGAT 
GTGAGATTTC CCATCAGGCT GGAAGGTTTG GTGCTAACCC ATCAGCAGTT CAGTAGTTAC 
GAGCCTGAAC TGTTTCCTGG TCTTATTTAT AGAATGGTAA AACCACGAAT TGTGTTGCTT 
ATCTTTGTAT CTGGAAAAGT TGTGTTGACA GGTGCCAAAG AACGTTCTGA GATCTATGAA 
GCATTTGAAA ACATCTATCC TATTCTAAAA GGTTTTAAAA AAGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TBP2 gene may not be associated with primary ovarian insufficiency.
Climacteric : the journal of the International Menopause Society19(6)565-567(2016 Dec)
Wang C,Cao J,Xing Y,Pu D,Liu J,Wu J

Switching of the core transcription machinery during myogenesis.
Genes & development21(17)2137-49(2007 Sep)
Deato MD,Tjian R

Genomics, evolution, and expression of TBPL2, a member of the TBP family.
DNA and cell biology26(6)369-85(2007 Jun)
Di Pietro C,Ragusa M,Duro L,Guglielmino MR,Barbagallo D,Carnemolla A,Lagan? A,Buffa P,Angelica R,Rinaldi A,Calafato MS,Milicia I,Caserta C,Giugno R,Pulvirenti A,Giunta V,Rapisarda A,Di Pietro V,Grillo A,Messina A,Ferro A,Grzeschik KH,Purrello M

TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed.
Proceedings of the National Academy of Sciences of the United States of America100(25)14887-91(2003 Dec)
Persengiev SP,Zhu X,Dixit BL,Maston GA,Kittler EL,Green MR

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TBPL2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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