KRT13 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRT13
Entrez Gene ID	3860
Full Name	keratin 13
Synonyms	CK13,K13,WSN2
General protein information	Preferred Names keratin 13 Names keratin, type I cytoskeletal 13 CK-13 cytokeratin 13 keratin 13, type I
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008].
Disorder MIM:	148065
Disorder Html:	White sponge nevus 2, 615785 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_153490.2	NP_705694.2	keratin, type I cytoskeletal 13 isoform a
NM_153490.3	NP_705694.3	keratin, type I cytoskeletal 13 isoform a
NM_002274.3	NP_002265.2	keratin, type I cytoskeletal 13 isoform b
NM_002274.4	NP_002265.3	keratin, type I cytoskeletal 13 isoform b

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KRT13	XP_003315487.1
Bos taurus (cattle)	KRT13	XP_002696036.1
Canis lupus familiaris (dog)	KRT13	XP_548106.4
Mus musculus (house mouse)	Krt13	NP_034792.1
Rattus norvegicus (Norway rat)	Krt13	NP_001004021.1
Xenopus tropicalis (tropical clawed frog)	krt15	XP_002939083.2
Homo sapiens (human)	KRT13	NP_705694.2

Gene Ontology
Bibliography

Related articles in PubMed

Keratin 13 gene is epigenetically suppressed during transforming growth factor-?1-induced epithelial-mesenchymal transition in a human keratinocyte cell line.
Hatta M, Miyake Y, Uchida K, Yamazaki J
Biochemical and biophysical research communications(2018 Jan)

Keratin 13 expression reprograms bone and brain metastases of human prostate cancer cells.
Li Q, Yin L, Jones LW, Chu GC, Wu JB, Huang JM, Li Q, You S, Kim J, Lu YT, Mrdenovic S, Wang R, Freeman MR, Garraway I, Lewis MS, Chung LW, Zhau HE
Oncotarget7(51)84645-84657(2016 Dec)

Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk.
Permuth JB, Pirie A, Ann Chen Y, Lin HY, Reid BM, Chen Z, Monteiro A, Dennis J, Mendoza-Fandino G, , , Anton-Culver H, Bandera EV, Bisogna M, Brinton L, Brooks-Wilson A, Carney ME, Chenevix-Trench G, Cook LS, Cramer DW, Cunningham JM, Cybulski C, D'Aloisio AA, Anne Doherty J, Earp M, Edwards RP, Fridley BL, Gayther SA, Gentry-Maharaj A, Goodman MT, Gronwald J, Hogdall E, Iversen ES, Jakubowska A, Jensen A, Karlan BY, Kelemen LE, Kjaer SK, Kraft P, Le ND, Levine DA, Lissowska J, Lubinski J, Matsuo K, Menon U, Modugno R, Moysich KB, Nakanishi T, Ness RB, Olson S, Orlow I, Pearce CL, Pejovic T, Poole EM, Ramus SJ, Anne Rossing M, Sandler DP, Shu XO, Song H, Taylor JA, Teo SH, Terry KL, Thompson PJ, Tworoger SS, Webb PM, Wentzensen N, Wilkens LR, Winham S, Woo YL, Wu AH, Yang H, Zheng W, Ziogas A, Phelan CM, Schildkraut JM, Berchuck A, Goode EL, Pharoah PD, Sellers TA,
Human molecular genetics25(16)3600-3612(2016 08)

Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone.
Liu S, Cadaneanu RM, Zhang B, Huo L, Lai K, Li X, Galet C, Grogan TR, Elashoff D, Freedland SJ, Rettig M, Aronson WJ, Knudsen BS, Lewis MS, Garraway IP
PloS one11(10)e0163232(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Four rare missense variants were identified (ACTBL2 rs73757391 (5q11.2), BTD rs200337373 (3p25.1), KRT13 rs150321809 (17q21.2) and MC2R rs104894658 (18p11.21)), but only MC2R rs104894668 had a large effect size (OR = 9.66).
Title: Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk.

KRT13 expression is associated with poor prognosis at multiple stages of disease progression
Title: Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone.

Decreased KRT13 was associated with Esophageal Squamous Cell Carcinoma.
Title: Kr?ppel-like Factor 4 Promotes Esophageal Squamous Cell Carcinoma Differentiation by Up-regulating Keratin 13 Expression.

Loss of CK13 expression is associated with invasive oral squamous cell carcinoma.
Title: Differential Expression of Cytokeratin 13 in Non-Neoplastic, Dysplastic and Neoplastic Oral Mucosa in a High Risk Pakistani Population.

Low KRT13 mRNA expression is associated with oral squamous cell carcinoma.
Title: KRT13, FAIM2 and CYP2W1 mRNA expression in oral squamous cell carcinoma patients with risk habits.

The following KRT13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRT13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu107835	NM_153490.3 Latest version!	Homo sapiens keratin 13 (KRT13), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu108464	NM_002274.4 Latest version!	Homo sapiens keratin 13 (KRT13), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu26448	NM_002274.3 Latest version!	Homo sapiens keratin 13 (KRT13), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu26483	NM_153490.2 Latest version!	Homo sapiens keratin 13 (KRT13), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRT13 ( NM_153490.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_705694.3 Homo sapiens keratin 13 (KRT13), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu107835
Clone ID Related Accession (Same CDS sequence)	NM_153490.3
Accession Version	NM_153490.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1377bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	keratin, type I cytoskeletal 13 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC019349.28. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_153490.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223077.1, ERR279827.5455.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147975, SAMEA2156670 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000246635.8/ ENSP00000246635.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCCTCC GCCTGCAGAG CTCCTCTGCC AGCTATGGAG GTGGTTTCGG GGGTGGCTCT 
TGCCAGCTGG GAGGAGGCCG TGGTGTCTCT ACCTGTTCAA CTCGGTTTGT GTCCGGGGGA 
TCAGCTGGGG GCTATGGAGG CGGCGTGAGC TGTGGTTTTG GTGGAGGGGC TGGTAGTGGC 
TTTGGAGGTG GCTATGGAGG TGGCCTTGGA GGTGGCTATG GAGGTGGCCT TGGAGGTGGC 
TTTGGTGGGG GTTTTGCTGG TGGCTTTGTT GACTTTGGTG CTTGTGATGG CGGCCTCCTC 
ACTGGCAATG AGAAGATCAC CATGCAGAAC CTCAACGACC GCCTGGCTTC CTACCTGGAG 
AAGGTGCGCG CCCTGGAGGA GGCCAACGCT GACCTGGAGG TGAAGATCCG TGACTGGCAC 
CTGAAGCAGA GCCCAGCTAG CCCTGAGCGG GACTACAGCC CCTACTACAA GACCATTGAA 
GAGCTCCGGG ACAAGATCCT GACCGCCACC ATTGAAAACA ACCGGGTCAT CCTGGAGATT 
GACAATGCCA GGCTGGCTGC GGACGACTTC AGGCTCAAGT ATGAGAATGA GCTGGCCCTG 
CGCCAGAGCG TGGAGGCCGA CATCAACGGC CTGCGCCGGG TGCTGGATGA GCTCACTCTG 
TCTAAGACTG ACCTGGAGAT GCAGATCGAG AGCCTGAATG AAGAGCTAGC CTACATGAAG 
AAGAACCATG AAGAGGAGAT GAAGGAATTT AGCAACCAGG TGGTCGGCCA GGTCAACGTG 
GAGATGGATG CCACCCCAGG CATTGACCTG ACCCGCGTGC TGGCAGAGAT GAGGGAGCAG 
TACGAGGCCA TGGCAGAGAG GAACCGCCGG GATGCTGAGG AATGGTTCCA CACCAAGAGT 
GCAGAGCTGA ACAAGGAGGT GTCTACCAAC ACTGCCATGA TTCAGACCAG CAAGACAGAG 
ATCACGGAGC TCAGGCGCAC GCTCCAAGGC CTGGAGATTG AGCTGCAGTC CCAGCTGAGC 
ATGAAAGCGG GGCTGGAGAA CACGGTGGCA GAGACGGAGT GCCGCTATGC CCTGCAGCTG 
CAGCAGATCC AGGGACTCAT CAGCAGCATC GAGGCCCAGC TGAGCGAGCT CCGCAGTGAG 
ATGGAGTGCC AGAACCAAGA GTACAAGATG CTGCTGGACA TCAAGACACG TCTGGAGCAG 
GAGATCGCCA CCTACCGCAG CCTGCTCGAG GGCCAGGACG CCAAGATGAT TGGTTTCCCT 
TCCTCAGCAG GAAGCGTCAG CCCCCGTAGC ACCTCTGTTA CCACGACTTC TAGTGCCTCT 
GTTACCACCA CCTCTAATGC CTCTGGTCGC CGCACTTCTG ATGTCCGTAG GCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_705694.3
CDS	63..1439
Translation	MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP

Target ORF information:

RefSeq Version	NM_153490.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 13 (KRT13), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153490.3

ORF Insert Sequence:

ATGAGCCTCC GCCTGCAGAG CTCCTCTGCC AGCTATGGAG GTGGTTTCGG GGGTGGCTCT 
TGCCAGCTGG GAGGAGGCCG TGGTGTCTCT ACCTGTTCAA CTCGGTTTGT GTCCGGGGGA 
TCAGCTGGGG GCTATGGAGG CGGCGTGAGC TGTGGTTTTG GTGGAGGGGC TGGTAGTGGC 
TTTGGAGGTG GCTATGGAGG TGGCCTTGGA GGTGGCTATG GAGGTGGCCT TGGAGGTGGC 
TTTGGTGGGG GTTTTGCTGG TGGCTTTGTT GACTTTGGTG CTTGTGATGG CGGCCTCCTC 
ACTGGCAATG AGAAGATCAC CATGCAGAAC CTCAACGACC GCCTGGCTTC CTACCTGGAG 
AAGGTGCGCG CCCTGGAGGA GGCCAACGCT GACCTGGAGG TGAAGATCCG TGACTGGCAC 
CTGAAGCAGA GCCCAGCTAG CCCTGAGCGG GACTACAGCC CCTACTACAA GACCATTGAA 
GAGCTCCGGG ACAAGATCCT GACCGCCACC ATTGAAAACA ACCGGGTCAT CCTGGAGATT 
GACAATGCCA GGCTGGCTGC GGACGACTTC AGGCTCAAGT ATGAGAATGA GCTGGCCCTG 
CGCCAGAGCG TGGAGGCCGA CATCAACGGC CTGCGCCGGG TGCTGGATGA GCTCACTCTG 
TCTAAGACTG ACCTGGAGAT GCAGATCGAG AGCCTGAATG AAGAGCTAGC CTACATGAAG 
AAGAACCATG AAGAGGAGAT GAAGGAATTT AGCAACCAGG TGGTCGGCCA GGTCAACGTG 
GAGATGGATG CCACCCCAGG CATTGACCTG ACCCGCGTGC TGGCAGAGAT GAGGGAGCAG 
TACGAGGCCA TGGCAGAGAG GAACCGCCGG GATGCTGAGG AATGGTTCCA CACCAAGAGT 
GCAGAGCTGA ACAAGGAGGT GTCTACCAAC ACTGCCATGA TTCAGACCAG CAAGACAGAG 
ATCACGGAGC TCAGGCGCAC GCTCCAAGGC CTGGAGATTG AGCTGCAGTC CCAGCTGAGC 
ATGAAAGCGG GGCTGGAGAA CACGGTGGCA GAGACGGAGT GCCGCTATGC CCTGCAGCTG 
CAGCAGATCC AGGGACTCAT CAGCAGCATC GAGGCCCAGC TGAGCGAGCT CCGCAGTGAG 
ATGGAGTGCC AGAACCAAGA GTACAAGATG CTGCTGGACA TCAAGACACG TCTGGAGCAG 
GAGATCGCCA CCTACCGCAG CCTGCTCGAG GGCCAGGACG CCAAGATGAT TGGTTTCCCT 
TCCTCAGCAG GAAGCGTCAG CCCCCGTAGC ACCTCTGTTA CCACGACTTC TAGTGCCTCT 
GTTACCACCA CCTCTAATGC CTCTGGTCGC CGCACTTCTG ATGTCCGTAG GCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRT13 ( NM_002274.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002265.3 Homo sapiens keratin 13 (KRT13), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu108464
Clone ID Related Accession (Same CDS sequence)	NM_002274.4
Accession Version	NM_002274.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1263bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	keratin, type I cytoskeletal 13 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC019349.28. On Jun 1, 2019 this sequence version replaced NM_002274.3. Transcript Variant: This variant (2) utilizes an alternate splice site in the 3' coding region, which results in a frameshift and early stop codon, compared to transcript variant 1. The encoded isoform (b) is shorter, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X52426.1, ERR279874.839.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147975, SAMEA2156670 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGCCTCC GCCTGCAGAG CTCCTCTGCC AGCTATGGAG GTGGTTTCGG GGGTGGCTCT 
TGCCAGCTGG GAGGAGGCCG TGGTGTCTCT ACCTGTTCAA CTCGGTTTGT GTCCGGGGGA 
TCAGCTGGGG GCTATGGAGG CGGCGTGAGC TGTGGTTTTG GTGGAGGGGC TGGTAGTGGC 
TTTGGAGGTG GCTATGGAGG TGGCCTTGGA GGTGGCTATG GAGGTGGCCT TGGAGGTGGC 
TTTGGTGGGG GTTTTGCTGG TGGCTTTGTT GACTTTGGTG CTTGTGATGG CGGCCTCCTC 
ACTGGCAATG AGAAGATCAC CATGCAGAAC CTCAACGACC GCCTGGCTTC CTACCTGGAG 
AAGGTGCGCG CCCTGGAGGA GGCCAACGCT GACCTGGAGG TGAAGATCCG TGACTGGCAC 
CTGAAGCAGA GCCCAGCTAG CCCTGAGCGG GACTACAGCC CCTACTACAA GACCATTGAA 
GAGCTCCGGG ACAAGATCCT GACCGCCACC ATTGAAAACA ACCGGGTCAT CCTGGAGATT 
GACAATGCCA GGCTGGCTGC GGACGACTTC AGGCTCAAGT ATGAGAATGA GCTGGCCCTG 
CGCCAGAGCG TGGAGGCCGA CATCAACGGC CTGCGCCGGG TGCTGGATGA GCTCACTCTG 
TCTAAGACTG ACCTGGAGAT GCAGATCGAG AGCCTGAATG AAGAGCTAGC CTACATGAAG 
AAGAACCATG AAGAGGAGAT GAAGGAATTT AGCAACCAGG TGGTCGGCCA GGTCAACGTG 
GAGATGGATG CCACCCCAGG CATTGACCTG ACCCGCGTGC TGGCAGAGAT GAGGGAGCAG 
TACGAGGCCA TGGCAGAGAG GAACCGCCGG GATGCTGAGG AATGGTTCCA CACCAAGAGT 
GCAGAGCTGA ACAAGGAGGT GTCTACCAAC ACTGCCATGA TTCAGACCAG CAAGACAGAG 
ATCACGGAGC TCAGGCGCAC GCTCCAAGGC CTGGAGATTG AGCTGCAGTC CCAGCTGAGC 
ATGAAAGCGG GGCTGGAGAA CACGGTGGCA GAGACGGAGT GCCGCTATGC CCTGCAGCTG 
CAGCAGATCC AGGGACTCAT CAGCAGCATC GAGGCCCAGC TGAGCGAGCT CCGCAGTGAG 
ATGGAGTGCC AGAACCAAGA GTACAAGATG CTGCTGGACA TCAAGACACG TCTGGAGCAG 
GAGATCGCCA CCTACCGCAG CCTGCTCGAG GGCCAGGACG CCAAGAAGCG TCAGCCCCCG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002265.3
CDS	63..1325
Translation	MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKKRQPP

Target ORF information:

RefSeq Version	NM_002274.4
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 13 (KRT13), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002274.4

ORF Insert Sequence:

ATGAGCCTCC GCCTGCAGAG CTCCTCTGCC AGCTATGGAG GTGGTTTCGG GGGTGGCTCT 
TGCCAGCTGG GAGGAGGCCG TGGTGTCTCT ACCTGTTCAA CTCGGTTTGT GTCCGGGGGA 
TCAGCTGGGG GCTATGGAGG CGGCGTGAGC TGTGGTTTTG GTGGAGGGGC TGGTAGTGGC 
TTTGGAGGTG GCTATGGAGG TGGCCTTGGA GGTGGCTATG GAGGTGGCCT TGGAGGTGGC 
TTTGGTGGGG GTTTTGCTGG TGGCTTTGTT GACTTTGGTG CTTGTGATGG CGGCCTCCTC 
ACTGGCAATG AGAAGATCAC CATGCAGAAC CTCAACGACC GCCTGGCTTC CTACCTGGAG 
AAGGTGCGCG CCCTGGAGGA GGCCAACGCT GACCTGGAGG TGAAGATCCG TGACTGGCAC 
CTGAAGCAGA GCCCAGCTAG CCCTGAGCGG GACTACAGCC CCTACTACAA GACCATTGAA 
GAGCTCCGGG ACAAGATCCT GACCGCCACC ATTGAAAACA ACCGGGTCAT CCTGGAGATT 
GACAATGCCA GGCTGGCTGC GGACGACTTC AGGCTCAAGT ATGAGAATGA GCTGGCCCTG 
CGCCAGAGCG TGGAGGCCGA CATCAACGGC CTGCGCCGGG TGCTGGATGA GCTCACTCTG 
TCTAAGACTG ACCTGGAGAT GCAGATCGAG AGCCTGAATG AAGAGCTAGC CTACATGAAG 
AAGAACCATG AAGAGGAGAT GAAGGAATTT AGCAACCAGG TGGTCGGCCA GGTCAACGTG 
GAGATGGATG CCACCCCAGG CATTGACCTG ACCCGCGTGC TGGCAGAGAT GAGGGAGCAG 
TACGAGGCCA TGGCAGAGAG GAACCGCCGG GATGCTGAGG AATGGTTCCA CACCAAGAGT 
GCAGAGCTGA ACAAGGAGGT GTCTACCAAC ACTGCCATGA TTCAGACCAG CAAGACAGAG 
ATCACGGAGC TCAGGCGCAC GCTCCAAGGC CTGGAGATTG AGCTGCAGTC CCAGCTGAGC 
ATGAAAGCGG GGCTGGAGAA CACGGTGGCA GAGACGGAGT GCCGCTATGC CCTGCAGCTG 
CAGCAGATCC AGGGACTCAT CAGCAGCATC GAGGCCCAGC TGAGCGAGCT CCGCAGTGAG 
ATGGAGTGCC AGAACCAAGA GTACAAGATG CTGCTGGACA TCAAGACACG TCTGGAGCAG 
GAGATCGCCA CCTACCGCAG CCTGCTCGAG GGCCAGGACG CCAAGAAGCG TCAGCCCCCG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRT13 ( NM_002274.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002265.2 Homo sapiens keratin 13 (KRT13), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26448
Clone ID Related Accession (Same CDS sequence)	NM_002274.3
Accession Version	NM_002274.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1263bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	keratin, type I cytoskeletal 13 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AK092276.1, BC077718.1, DR422220.1 and X52426.1. On Mar 14, 2007 this sequence version replaced NM_002274.2. Transcript Variant: This variant (2) utilizes an alternate splice site in the 3' coding region, which results in a frameshift and early stop codon, compared to transcript variant 1. The encoded isoform (b) is shorter, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X52426.1, ERR279874.839.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147975, SAMEA2156670 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGCCTCC GCCTGCAGAG CTCCTCTGCC AGCTATGGAG GTGGTTTCGG GGGTGGCTCT 
TGCCAGCTGG GAGGAGGCCG TGGTGTCTCT ACCTGTTCAA CTCGGTTTGT GTCTGGGGGA 
TCAGCTGGGG GCTATGGAGG CGGCGTGAGC TGTGGTTTTG GTGGAGGGGC TGGTAGTGGC 
TTTGGAGGTG GCTATGGAGG TGGCCTTGGA GGTGGCTATG GAGGTGGCCT TGGAGGTGGC 
TTTGGTGGGG GTTTTGCTGG TGGCTTTGTT GACTTTGGTG CTTGTGATGG CGGCCTCCTC 
ACTGGCAATG AGAAGATCAC CATGCAGAAC CTCAACGACC GCCTGGCTTC CTACCTGGAG 
AAGGTGCGCG CCCTGGAGGA GGCCAACGCT GACCTGGAGG TGAAGATCCG TGACTGGCAC 
CTGAAGCAGA GCCCAGCTAG CCCTGAGCGG GACTACAGCC CCTACTACAA GACCATTGAA 
GAGCTCCGGG ACAAGATCCT GACCGCCACC ATTGAAAACA ACCGGGTCAT CCTGGAGATT 
GACAATGCCA GGCTGGCTGC GGACGACTTC AGGCTCAAGT ATGAGAATGA GCTGGCCCTG 
CGCCAGAGCG TGGAGGCCGA CATCAACGGC CTGCGCCGGG TGCTGGATGA GCTCACTCTG 
TCTAAGACTG ACCTGGAGAT GCAGATCGAG AGCCTGAATG AAGAGCTAGC CTACATGAAG 
AAGAACCATG AAGAGGAGAT GAAGGAATTT AGCAACCAGG TGGTCGGCCA GGTCAACGTG 
GAGATGGATG CCACCCCAGG CATTGACCTG ACCCGCGTGC TGGCAGAGAT GAGGGAGCAG 
TACGAGGCCA TGGCAGAGAG GAACCGCCGG GATGCTGAGG AATGGTTCCA CGCCAAGAGT 
GCAGAGCTGA ACAAGGAGGT GTCTACCAAC ACTGCCATGA TTCAGACCAG CAAGACAGAG 
ATCACGGAGC TCAGGCGCAC GCTCCAAGGC CTGGAGATTG AGCTGCAGTC CCAGCTGAGC 
ATGAAAGCGG GGCTGGAGAA CACGGTGGCA GAGACGGAGT GCCGCTATGC CCTGCAGCTG 
CAGCAGATCC AGGGACTCAT CAGCAGCATC GAGGCCCAGC TGAGCGAGCT CCGCAGTGAG 
ATGGAGTGCC AGAACCAAGA GTACAAGATG CTGCTGGACA TCAAGACACG TCTGGAGCAG 
GAGATCGCCA CCTACCGCAG CCTGCTCGAG GGCCAGGACG CCAAGAAGCG TCAGCCCCCG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002265.2
CDS	64..1326
Translation	MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKKRQPP

Target ORF information:

RefSeq Version	NM_002274.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 13 (KRT13), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002274.3

ORF Insert Sequence:

ATGAGCCTCC GCCTGCAGAG CTCCTCTGCC AGCTATGGAG GTGGTTTCGG GGGTGGCTCT 
TGCCAGCTGG GAGGAGGCCG TGGTGTCTCT ACCTGTTCAA CTCGGTTTGT GTCTGGGGGA 
TCAGCTGGGG GCTATGGAGG CGGCGTGAGC TGTGGTTTTG GTGGAGGGGC TGGTAGTGGC 
TTTGGAGGTG GCTATGGAGG TGGCCTTGGA GGTGGCTATG GAGGTGGCCT TGGAGGTGGC 
TTTGGTGGGG GTTTTGCTGG TGGCTTTGTT GACTTTGGTG CTTGTGATGG CGGCCTCCTC 
ACTGGCAATG AGAAGATCAC CATGCAGAAC CTCAACGACC GCCTGGCTTC CTACCTGGAG 
AAGGTGCGCG CCCTGGAGGA GGCCAACGCT GACCTGGAGG TGAAGATCCG TGACTGGCAC 
CTGAAGCAGA GCCCAGCTAG CCCTGAGCGG GACTACAGCC CCTACTACAA GACCATTGAA 
GAGCTCCGGG ACAAGATCCT GACCGCCACC ATTGAAAACA ACCGGGTCAT CCTGGAGATT 
GACAATGCCA GGCTGGCTGC GGACGACTTC AGGCTCAAGT ATGAGAATGA GCTGGCCCTG 
CGCCAGAGCG TGGAGGCCGA CATCAACGGC CTGCGCCGGG TGCTGGATGA GCTCACTCTG 
TCTAAGACTG ACCTGGAGAT GCAGATCGAG AGCCTGAATG AAGAGCTAGC CTACATGAAG 
AAGAACCATG AAGAGGAGAT GAAGGAATTT AGCAACCAGG TGGTCGGCCA GGTCAACGTG 
GAGATGGATG CCACCCCAGG CATTGACCTG ACCCGCGTGC TGGCAGAGAT GAGGGAGCAG 
TACGAGGCCA TGGCAGAGAG GAACCGCCGG GATGCTGAGG AATGGTTCCA CGCCAAGAGT 
GCAGAGCTGA ACAAGGAGGT GTCTACCAAC ACTGCCATGA TTCAGACCAG CAAGACAGAG 
ATCACGGAGC TCAGGCGCAC GCTCCAAGGC CTGGAGATTG AGCTGCAGTC CCAGCTGAGC 
ATGAAAGCGG GGCTGGAGAA CACGGTGGCA GAGACGGAGT GCCGCTATGC CCTGCAGCTG 
CAGCAGATCC AGGGACTCAT CAGCAGCATC GAGGCCCAGC TGAGCGAGCT CCGCAGTGAG 
ATGGAGTGCC AGAACCAAGA GTACAAGATG CTGCTGGACA TCAAGACACG TCTGGAGCAG 
GAGATCGCCA CCTACCGCAG CCTGCTCGAG GGCCAGGACG CCAAGAAGCG TCAGCCCCCG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRT13 ( NM_153490.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_705694.2 Homo sapiens keratin 13 (KRT13), transcript variant 1, mRNA.

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CloneID	OHu26483
Clone ID Related Accession (Same CDS sequence)	NM_153490.2
Accession Version	NM_153490.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1377bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-26
Organism	Homo sapiens(human)
Product	keratin, type I cytoskeletal 13 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AK092276.1, BC077718.1, DR422220.1, BC126184.1 and X52426.1. This sequence is a reference standard in the RefSeqGene project. On Mar 14, 2007 this sequence version replaced NM_153490.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223077.1, ERR279842.370.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147975, SAMEA2156670 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGCCTCC GCCTGCAGAG CTCCTCTGCC AGCTATGGAG GTGGTTTCGG GGGTGGCTCT 
TGCCAGCTGG GAGGAGGCCG TGGTGTCTCT ACCTGTTCAA CTCGGTTTGT GTCTGGGGGA 
TCAGCTGGGG GCTATGGAGG CGGCGTGAGC TGTGGTTTTG GTGGAGGGGC TGGTAGTGGC 
TTTGGAGGTG GCTATGGAGG TGGCCTTGGA GGTGGCTATG GAGGTGGCCT TGGAGGTGGC 
TTTGGTGGGG GTTTTGCTGG TGGCTTTGTT GACTTTGGTG CTTGTGATGG CGGCCTCCTC 
ACTGGCAATG AGAAGATCAC CATGCAGAAC CTCAACGACC GCCTGGCTTC CTACCTGGAG 
AAGGTGCGCG CCCTGGAGGA GGCCAACGCT GACCTGGAGG TGAAGATCCG TGACTGGCAC 
CTGAAGCAGA GCCCAGCTAG CCCTGAGCGG GACTACAGCC CCTACTACAA GACCATTGAA 
GAGCTCCGGG ACAAGATCCT GACCGCCACC ATTGAAAACA ACCGGGTCAT CCTGGAGATT 
GACAATGCCA GGCTGGCTGC GGACGACTTC AGGCTCAAGT ATGAGAATGA GCTGGCCCTG 
CGCCAGAGCG TGGAGGCCGA CATCAACGGC CTGCGCCGGG TGCTGGATGA GCTCACTCTG 
TCTAAGACTG ACCTGGAGAT GCAGATCGAG AGCCTGAATG AAGAGCTAGC CTACATGAAG 
AAGAACCATG AAGAGGAGAT GAAGGAATTT AGCAACCAGG TGGTCGGCCA GGTCAACGTG 
GAGATGGATG CCACCCCAGG CATTGACCTG ACCCGCGTGC TGGCAGAGAT GAGGGAGCAG 
TACGAGGCCA TGGCAGAGAG GAACCGCCGG GATGCTGAGG AATGGTTCCA CGCCAAGAGT 
GCAGAGCTGA ACAAGGAGGT GTCTACCAAC ACTGCCATGA TTCAGACCAG CAAGACAGAG 
ATCACGGAGC TCAGGCGCAC GCTCCAAGGC CTGGAGATTG AGCTGCAGTC CCAGCTGAGC 
ATGAAAGCGG GGCTGGAGAA CACGGTGGCA GAGACGGAGT GCCGCTATGC CCTGCAGCTG 
CAGCAGATCC AGGGACTCAT CAGCAGCATC GAGGCCCAGC TGAGCGAGCT CCGCAGTGAG 
ATGGAGTGCC AGAACCAAGA GTACAAGATG CTGCTGGACA TCAAGACACG TCTGGAGCAG 
GAGATCGCCA CCTACCGCAG CCTGCTCGAG GGCCAGGACG CCAAGATGAT TGGTTTCCCT 
TCCTCAGCAG GAAGCGTCAG CCCCCGTAGC ACCTCTGTTA CCACGACTTC TAGTGCCTCT 
GTTACCACCA CCTCTAATGC CTCTGGTCGC CGCACTTCTG ATGTCCGTAG GCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_705694.2
CDS	64..1440
Translation	MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP

Target ORF information:

RefSeq Version	NM_153490.2
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin 13 (KRT13), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153490.2

ORF Insert Sequence:

ATGAGCCTCC GCCTGCAGAG CTCCTCTGCC AGCTATGGAG GTGGTTTCGG GGGTGGCTCT 
TGCCAGCTGG GAGGAGGCCG TGGTGTCTCT ACCTGTTCAA CTCGGTTTGT GTCTGGGGGA 
TCAGCTGGGG GCTATGGAGG CGGCGTGAGC TGTGGTTTTG GTGGAGGGGC TGGTAGTGGC 
TTTGGAGGTG GCTATGGAGG TGGCCTTGGA GGTGGCTATG GAGGTGGCCT TGGAGGTGGC 
TTTGGTGGGG GTTTTGCTGG TGGCTTTGTT GACTTTGGTG CTTGTGATGG CGGCCTCCTC 
ACTGGCAATG AGAAGATCAC CATGCAGAAC CTCAACGACC GCCTGGCTTC CTACCTGGAG 
AAGGTGCGCG CCCTGGAGGA GGCCAACGCT GACCTGGAGG TGAAGATCCG TGACTGGCAC 
CTGAAGCAGA GCCCAGCTAG CCCTGAGCGG GACTACAGCC CCTACTACAA GACCATTGAA 
GAGCTCCGGG ACAAGATCCT GACCGCCACC ATTGAAAACA ACCGGGTCAT CCTGGAGATT 
GACAATGCCA GGCTGGCTGC GGACGACTTC AGGCTCAAGT ATGAGAATGA GCTGGCCCTG 
CGCCAGAGCG TGGAGGCCGA CATCAACGGC CTGCGCCGGG TGCTGGATGA GCTCACTCTG 
TCTAAGACTG ACCTGGAGAT GCAGATCGAG AGCCTGAATG AAGAGCTAGC CTACATGAAG 
AAGAACCATG AAGAGGAGAT GAAGGAATTT AGCAACCAGG TGGTCGGCCA GGTCAACGTG 
GAGATGGATG CCACCCCAGG CATTGACCTG ACCCGCGTGC TGGCAGAGAT GAGGGAGCAG 
TACGAGGCCA TGGCAGAGAG GAACCGCCGG GATGCTGAGG AATGGTTCCA CGCCAAGAGT 
GCAGAGCTGA ACAAGGAGGT GTCTACCAAC ACTGCCATGA TTCAGACCAG CAAGACAGAG 
ATCACGGAGC TCAGGCGCAC GCTCCAAGGC CTGGAGATTG AGCTGCAGTC CCAGCTGAGC 
ATGAAAGCGG GGCTGGAGAA CACGGTGGCA GAGACGGAGT GCCGCTATGC CCTGCAGCTG 
CAGCAGATCC AGGGACTCAT CAGCAGCATC GAGGCCCAGC TGAGCGAGCT CCGCAGTGAG 
ATGGAGTGCC AGAACCAAGA GTACAAGATG CTGCTGGACA TCAAGACACG TCTGGAGCAG 
GAGATCGCCA CCTACCGCAG CCTGCTCGAG GGCCAGGACG CCAAGATGAT TGGTTTCCCT 
TCCTCAGCAG GAAGCGTCAG CCCCCGTAGC ACCTCTGTTA CCACGACTTC TAGTGCCTCT 
GTTACCACCA CCTCTAATGC CTCTGGTCGC CGCACTTCTG ATGTCCGTAG GCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Keratin 13 gene is epigenetically suppressed during transforming growth factor-?1-induced epithelial-mesenchymal transition in a human keratinocyte cell line.
Biochemical and biophysical research communications(2018 Jan)
Hatta M,Miyake Y,Uchida K,Yamazaki J

Keratin 13 expression reprograms bone and brain metastases of human prostate cancer cells.
Oncotarget7(51)84645-84657(2016 Dec)
Li Q,Yin L,Jones LW,Chu GC,Wu JB,Huang JM,Li Q,You S,Kim J,Lu YT,Mrdenovic S,Wang R,Freeman MR,Garraway I,Lewis MS,Chung LW,Zhau HE

Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk.
Human molecular genetics25(16)3600-3612(2016 08)
Permuth JB,Pirie A,Ann Chen Y,Lin HY,Reid BM,Chen Z,Monteiro A,Dennis J,Mendoza-Fandino G,,,Anton-Culver H,Bandera EV,Bisogna M,Brinton L,Brooks-Wilson A,Carney ME,Chenevix-Trench G,Cook LS,Cramer DW,Cunningham JM,Cybulski C,D'Aloisio AA,Anne Doherty J,Earp M,Edwards RP,Fridley BL,Gayther SA,Gentry-Maharaj A,Goodman MT,Gronwald J,Hogdall E,Iversen ES,Jakubowska A,Jensen A,Karlan BY,Kelemen LE,Kjaer SK,Kraft P,Le ND,Levine DA,Lissowska J,Lubinski J,Matsuo K,Menon U,Modugno R,Moysich KB,Nakanishi T,Ness RB,Olson S,Orlow I,Pearce CL,Pejovic T,Poole EM,Ramus SJ,Anne Rossing M,Sandler DP,Shu XO,Song H,Taylor JA,Teo SH,Terry KL,Thompson PJ,Tworoger SS,Webb PM,Wentzensen N,Wilkens LR,Winham S,Woo YL,Wu AH,Yang H,Zheng W,Ziogas A,Phelan CM,Schildkraut JM,Berchuck A,Goode EL,Pharoah PD,Sellers TA,

Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone.
PloS one11(10)e0163232(2016)
Liu S,Cadaneanu RM,Zhang B,Huo L,Lai K,Li X,Galet C,Grogan TR,Elashoff D,Freedland SJ,Rettig M,Aronson WJ,Knudsen BS,Lewis MS,Garraway IP

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KRT13 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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