KIF22 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KIF22
Entrez Gene ID	3835
Full Name	kinesin family member 22
Synonyms	A-328A3.2,KID,KNSL4,OBP,OBP-1,OBP-2,SEMDJL2
General protein information	Preferred Names kinesin family member 22 Names kinesin-like protein KIF22 kinesin-like DNA-binding protein pseudogene kinesin-like protein 4 oriP binding protein origin of plasmid DNA replication-binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Summary	The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
Disorder MIM:	603213
Disorder Html:	Spondyloepimetaphyseal dysplasia with joint laxity, type 2, 603546 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001256269.1	NP_001243198.1	kinesin-like protein KIF22 isoform 2
XM_024450270.1	XP_024306038.1	kinesin-like protein KIF22 isoform X1
NM_001256269.2	NP_001243198.1	kinesin-like protein KIF22 isoform 2
NM_007317.2	NP_015556.1	kinesin-like protein KIF22 isoform 1
NM_007317.3	NP_015556.1	kinesin-like protein KIF22 isoform 1
NM_001256270.1	NP_001243199.1	kinesin-like protein KIF22 isoform 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Kif22	NP_001009645.1
Homo sapiens (human)	KIF22	NP_015556.1
	KIF22	XP_001104365.2
Xenopus tropicalis (tropical clawed frog)	kif22	NP_989245.1
Danio rerio (zebrafish)	kif22	NP_001107063.1
Canis lupus familiaris (dog)	KIF22	XP_547058.3
Mus musculus (house mouse)	Kif22	NP_663563.1
Pan troglodytes (chimpanzee)	KIF22	XP_510910.3
Bos taurus (cattle)	KIF22	NP_001095338.2

Gene Ontology
Bibliography

Related articles in PubMed

Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules.
Iemura K, Tanaka K
Nature communications66447(2015 Mar)

Inhibition of KIF22 suppresses cancer cell proliferation by delaying mitotic exit through upregulating CDC25C expression.
Yu Y, Wang XY, Sun L, Wang YL, Wan YF, Li XQ, Feng YM
Carcinogenesis35(6)1416-25(2014 Jun)

Seventy-five genetic loci influencing the human red blood cell.
van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan ST, Voss K, Weichenberger CX, Albers CA, Al-Hussani A, Asselbergs FW, Ciullo M, Danjou F, Dina C, Esko T, Evans DM, Franke L, G?gele M, Hartiala J, Hersch M, Holm H, Hottenga JJ, Kanoni S, Kleber ME, Lagou V, Langenberg C, Lopez LM, Lyytik?inen LP, Melander O, Murgia F, Nolte IM, O'Reilly PF, Padmanabhan S, Parsa A, Pirastu N, Porcu E, Portas L, Prokopenko I, Ried JS, Shin SY, Tang CS, Teumer A, Traglia M, Ulivi S, Westra HJ, Yang J, Zhao JH, Anni F, Abdellaoui A, Attwood A, Balkau B, Bandinelli S, Bastardot F, Benyamin B, Boehm BO, Cookson WO, Das D, de Bakker PI, de Boer RA, de Geus EJ, de Moor MH, Dimitriou M, Domingues FS, D?ring A, Engstr?m G, Eyjolfsson GI, Ferrucci L, Fischer K, Galanello R, Garner SF, Genser B, Gibson QD, Girotto G, Gudbjartsson DF, Harris SE, Hartikainen AL, Hastie CE, Hedblad B, Illig T, Jolley J, K?h?nen M, Kema IP, Kemp JP, Liang L, Lloyd-Jones H, Loos RJ, Meacham S, Medland SE, Meisinger C, Memari Y, Mihailov E, Miller K, Moffatt MF, Nauck M, Novatchkova M, Nutile T, Olafsson I, Onundarson PT, Parracciani D, Penninx BW, Perseu L, Piga A, Pistis G, Pouta A, Puc U, Raitakari O, Ring SM, Robino A, Ruggiero D, Ruokonen A, Saint-Pierre A, Sala C, Salumets A, Sambrook J, Schepers H, Schmidt CO, Sillj? HH, Sladek R, Smit JH, Starr JM, Stephens J, Sulem P, Tanaka T, Thorsteinsdottir U, Tragante V, van Gilst WH, van Pelt LJ, van Veldhuisen DJ, V?lker U, Whitfield JB, Willemsen G, Winkelmann BR, Wirnsberger G, Algra A, Cucca F, d'Adamo AP, Danesh J, Deary IJ, Dominiczak AF, Elliott P, Fortina P, Froguel P, Gasparini P, Greinacher A, Hazen SL, Jarvelin MR, Khaw KT, Lehtim?ki T, Maerz W, Martin NG, Metspalu A, Mitchell BD, Montgomery GW, Moore C, Navis G, Pirastu M, Pramstaller PP, Ramirez-Solis R, Schadt E, Scott J, Shuldiner AR, Smith GD, Smith JG, Snieder H, Sorice R, Spector TD, Stefansson K, Stumvoll M, Tang WH, Toniolo D, T?njes A, Visscher PM, Vollenweider P, Wareham NJ, Wolffenbuttel BH, Boomsma DI, Beckmann JS, Dedoussis GV, Deloukas P, Ferreira MA, Sanna S, Uda M, Hicks AA, Penninger JM, Gieger C, Kooner JS, Ouwehand WH, Soranzo N, Chambers JC
Nature492(7429)369-75(2012 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules.
Title: Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules.

we conclude that inhibition of KIF22 suppresses cancer cell proliferation by delaying mitotic exit through the transcriptional upregulation of CDC25C.
Title: Inhibition of KIF22 suppresses cancer cell proliferation by delaying mitotic exit through upregulating CDC25C expression.

Whole-exome sequencing identifies mutations of KIF22 in spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type
Title: Whole-exome sequencing identifies mutations of KIF22 in spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type.

Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity
Title: Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity.

in all breast tumor tissues analyzed, variations in the Kid/KIF22 mRNA levels mirrored those seen with SIAH-1 mRNAs.
Title: Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes.

The following KIF22 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KIF22 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11567	NM_001256270.1 Latest version!	Homo sapiens kinesin family member 22 (KIF22), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu11567	NM_001256269.2 Latest version!	Homo sapiens kinesin family member 22 (KIF22), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu20210	NM_007317.3 Latest version!	Homo sapiens kinesin family member 22 (KIF22), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu104139	XM_024450270.1 Latest version!	Homo sapiens kinesin family member 22 (KIF22), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu11567	NM_001256269.1	Homo sapiens kinesin family member 22 (KIF22), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu20210	NM_007317.2	Homo sapiens kinesin family member 22 (KIF22), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KIF22 ( NM_007317.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_015556.1 Homo sapiens kinesin family member 22 (KIF22), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20210
Clone ID Related Accession (Same CDS sequence)	NM_007317.2 , NM_007317.3
Accession Version	NM_007317.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1998bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-06
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF22 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC370294.1, BC028155.1 and AK223431.1. This sequence is a reference standard in the RefSeqGene project. On Jan 14, 2012 this sequence version replaced NM_007317.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC028155.1, BC004352.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCGG GCGGCTCGAC GCAGCAGAGG CGACGCGAGA TGGCGGCAGC TTCAGCGGCG 
GCGATCTCAG GAGCTGGTCG CTGTCGGCTA AGCAAGATTG GAGCTACTCG TCGTCCACCT 
CCAGCTCGCG TAAGGGTGGC TGTGCGACTG CGGCCATTTG TGGATGGAAC AGCGGGAGCA 
AGTGATCCCC CCTGTGTGCG GGGCATGGAC AGCTGCTCTC TAGAGATTGC TAACTGGAGG 
AACCACCAGG AGACTCTCAA ATACCAGTTT GATGCCTTCT ATGGGGAGAG GAGTACTCAG 
CAGGACATCT ATGCAGGTTC AGTGCAGCCC ATCCTAAGGC ACTTGCTGGA AGGGCAGAAT 
GCCAGTGTGC TTGCCTATGG ACCCACAGGA GCTGGGAAGA CGCACACAAT GCTGGGCAGC 
CCAGAGCAAC CTGGGGTGAT CCCGCGGGCT CTCATGGACC TCCTGCAGCT CACAAGGGAG 
GAGGGTGCCG AGGGCCGGCC ATGGGCCCTT TCTGTCACCA TGTCTTACCT AGAGATCTAC 
CAGGAGAAGG TATTAGACCT CCTGGACCCT GCTTCGGGAG ACCTGGTAAT CCGAGAAGAC 
TGCCGGGGGA ATATCCTGAT TCCGGGTCTC TCCCAGAAGC CCATCAGTAG CTTTGCTGAT 
TTTGAGCGGC ACTTCCTGCC AGCCAGTCGA AATCGGACTG TAGGAGCCAC CCGGCTCAAC 
CAGCGCTCCT CCCGCAGTCA TGCTGTGCTC CTGGTCAAGG TGGACCAGCG GGAACGTTTG 
GCCCCATTTC GCCAGCGAGA GGGAAAACTC TACCTGATTG ACTTGGCTGG GTCAGAGGAC 
AACCGGCGCA CAGGCAACAA GGGCCTTCGG CTAAAAGAGA GTGGAGCCAT CAACACCTCC 
CTGTTTGTCC TGGGCAAAGT GGTAGATGCG CTGAATCAGG GCCTCCCTCG TGTACCTTAT 
CGGGACAGCA AGCTCACTCG CCTATTGCAG GACTCTCTGG GTGGCTCAGC CCACAGTATC 
CTTATTGCCA ACATTGCCCC TGAGAGACGC TTCTACCTAG ACACAGTCTC CGCACTCAAC 
TTTGCTGCCA GGTCCAAGGA GGTGATCAAT CGGCCTTTTA CCAATGAGAG CCTGCAGCCT 
CATGCCTTGG GACCTGTTAA GCTGTCTCAG AAAGAATTGC TTGGTCCACC AGAGGCAAAG 
AGAGCCCGAG GCCCTGAGGA AGAGGAGATC GGGAGCCCTG AGCCCATGGC AGCTCCAGCC 
TCTGCCTCCC AGAAACTCAG CCCCCTACAG AAGCTAAGCA GCATGGACCC GGCCATGCTG 
GAGCGCCTCC TCAGCTTGGA CCGTCTGCTT GCCTCCCAGG GGAGCCAGGG GGCCCCTCTG 
TTGAGTACCC CAAAGCGAGA GCGGATGGTG CTAATGAAGA CAGTGGAAGA GAAGGACCTA 
GAGATTGAGA GGCTTAAGAC GAAGCAAAAA GAACTGGAGG CCAAGATGTT GGCCCAGAAG 
GCTGAGGAAA AGGAGAACCA TTGTCCCACA ATGCTCCGGC CCCTTTCACA TCGCACAGTC 
ACAGGGGCAA AGCCCCTGAA AAAGGCTGTG GTGATGCCCC TACAGCTAAT TCAGGAGCAG 
GCAGCATCCC CAAATGCCGA GATCCACATC CTGAAGAATA AAGGCCGGAA GAGAAAGCTG 
GAGTCCCTGG ATGCCCTAGA GCCTGAGGAG AAGGCTGAGG ACTGCTGGGA GCTACAGATC 
AGCCCGGAGC TACTGGCTCA TGGGCGCCAA AAAATACTGG ATCTGCTGAA CGAAGGCTCA 
GCCCGAGATC TCCGCAGTCT TCAGCGCATT GGCCCGAAGA AGGCCCAGCT AATCGTGGGC 
TGGCGGGAGC TCCACGGCCC CTTCAGCCAG GTGGAGGACC TGGAACGCGT GGAGGGCATA 
ACGGGGAAAC AGATGGAGTC CTTCCTGAAG GCAAACATCC TGGGTCTCGC CGCCGGCCAG 
CGCTGTGGCG CCTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_015556.1
CDS	48..2045
Translation	MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS

Target ORF information:

RefSeq Version	NM_007317.2
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 22 (KIF22), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007317.2

ORF Insert Sequence:

ATGGCCGCGG GCGGCTCGAC GCAGCAGAGG CGACGCGAGA TGGCGGCAGC TTCAGCGGCG 
GCGATCTCAG GAGCTGGTCG CTGTCGGCTA AGCAAGATTG GAGCTACTCG TCGTCCACCT 
CCAGCTCGCG TAAGGGTGGC TGTGCGACTG CGGCCATTTG TGGATGGAAC AGCGGGAGCA 
AGTGATCCCC CCTGTGTGCG GGGCATGGAC AGCTGCTCTC TAGAGATTGC TAACTGGAGG 
AACCACCAGG AGACTCTCAA ATACCAGTTT GATGCCTTCT ATGGGGAGAG GAGTACTCAG 
CAGGACATCT ATGCAGGTTC AGTGCAGCCC ATCCTAAGGC ACTTGCTGGA AGGGCAGAAT 
GCCAGTGTGC TTGCCTATGG ACCCACAGGA GCTGGGAAGA CGCACACAAT GCTGGGCAGC 
CCAGAGCAAC CTGGGGTGAT CCCGCGGGCT CTCATGGACC TCCTGCAGCT CACAAGGGAG 
GAGGGTGCCG AGGGCCGGCC ATGGGCCCTT TCTGTCACCA TGTCTTACCT AGAGATCTAC 
CAGGAGAAGG TATTAGACCT CCTGGACCCT GCTTCGGGAG ACCTGGTAAT CCGAGAAGAC 
TGCCGGGGGA ATATCCTGAT TCCGGGTCTC TCCCAGAAGC CCATCAGTAG CTTTGCTGAT 
TTTGAGCGGC ACTTCCTGCC AGCCAGTCGA AATCGGACTG TAGGAGCCAC CCGGCTCAAC 
CAGCGCTCCT CCCGCAGTCA TGCTGTGCTC CTGGTCAAGG TGGACCAGCG GGAACGTTTG 
GCCCCATTTC GCCAGCGAGA GGGAAAACTC TACCTGATTG ACTTGGCTGG GTCAGAGGAC 
AACCGGCGCA CAGGCAACAA GGGCCTTCGG CTAAAAGAGA GTGGAGCCAT CAACACCTCC 
CTGTTTGTCC TGGGCAAAGT GGTAGATGCG CTGAATCAGG GCCTCCCTCG TGTACCTTAT 
CGGGACAGCA AGCTCACTCG CCTATTGCAG GACTCTCTGG GTGGCTCAGC CCACAGTATC 
CTTATTGCCA ACATTGCCCC TGAGAGACGC TTCTACCTAG ACACAGTCTC CGCACTCAAC 
TTTGCTGCCA GGTCCAAGGA GGTGATCAAT CGGCCTTTTA CCAATGAGAG CCTGCAGCCT 
CATGCCTTGG GACCTGTTAA GCTGTCTCAG AAAGAATTGC TTGGTCCACC AGAGGCAAAG 
AGAGCCCGAG GCCCTGAGGA AGAGGAGATC GGGAGCCCTG AGCCCATGGC AGCTCCAGCC 
TCTGCCTCCC AGAAACTCAG CCCCCTACAG AAGCTAAGCA GCATGGACCC GGCCATGCTG 
GAGCGCCTCC TCAGCTTGGA CCGTCTGCTT GCCTCCCAGG GGAGCCAGGG GGCCCCTCTG 
TTGAGTACCC CAAAGCGAGA GCGGATGGTG CTAATGAAGA CAGTGGAAGA GAAGGACCTA 
GAGATTGAGA GGCTTAAGAC GAAGCAAAAA GAACTGGAGG CCAAGATGTT GGCCCAGAAG 
GCTGAGGAAA AGGAGAACCA TTGTCCCACA ATGCTCCGGC CCCTTTCACA TCGCACAGTC 
ACAGGGGCAA AGCCCCTGAA AAAGGCTGTG GTGATGCCCC TACAGCTAAT TCAGGAGCAG 
GCAGCATCCC CAAATGCCGA GATCCACATC CTGAAGAATA AAGGCCGGAA GAGAAAGCTG 
GAGTCCCTGG ATGCCCTAGA GCCTGAGGAG AAGGCTGAGG ACTGCTGGGA GCTACAGATC 
AGCCCGGAGC TACTGGCTCA TGGGCGCCAA AAAATACTGG ATCTGCTGAA CGAAGGCTCA 
GCCCGAGATC TCCGCAGTCT TCAGCGCATT GGCCCGAAGA AGGCCCAGCT AATCGTGGGC 
TGGCGGGAGC TCCACGGCCC CTTCAGCCAG GTGGAGGACC TGGAACGCGT GGAGGGCATA 
ACGGGGAAAC AGATGGAGTC CTTCCTGAAG GCAAACATCC TGGGTCTCGC CGCCGGCCAG 
CGCTGTGGCG CCTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIF22 ( NM_001256269.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243198.1 Homo sapiens kinesin family member 22 (KIF22), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11567
Clone ID Related Accession (Same CDS sequence)	NM_001256269.1 , NM_001256269.2 , NM_001256270.1
Accession Version	NM_001256269.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF22 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC370294.1, AK316389.1, AK223431.1 and BC028155.1. Transcript Variant: This variant (2) has an additional exon in the 5' region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus than isoform 1. Variants 2 and 3 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK316389.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END##

ATGGACAGCT GCTCTCTAGA GATTGCTAAC TGGAGGAACC ACCAGGAGAC TCTCAAATAC 
CAGTTTGATG CCTTCTATGG GGAGAGGAGT ACTCAGCAGG ACATCTATGC AGGTTCAGTG 
CAGCCCATCC TAAGGCACTT GCTGGAAGGG CAGAATGCCA GTGTGCTTGC CTATGGACCC 
ACAGGAGCTG GGAAGACGCA CACAATGCTG GGCAGCCCAG AGCAACCTGG GGTGATCCCG 
CGGGCTCTCA TGGACCTCCT GCAGCTCACA AGGGAGGAGG GTGCCGAGGG CCGGCCATGG 
GCCCTTTCTG TCACCATGTC TTACCTAGAG ATCTACCAGG AGAAGGTATT AGACCTCCTG 
GACCCTGCTT CGGGAGACCT GGTAATCCGA GAAGACTGCC GGGGGAATAT CCTGATTCCG 
GGTCTCTCCC AGAAGCCCAT CAGTAGCTTT GCTGATTTTG AGCGGCACTT CCTGCCAGCC 
AGTCGAAATC GGACTGTAGG AGCCACCCGG CTCAACCAGC GCTCCTCCCG CAGTCATGCT 
GTGCTCCTGG TCAAGGTGGA CCAGCGGGAA CGTTTGGCCC CATTTCGCCA GCGAGAGGGA 
AAACTCTACC TGATTGACTT GGCTGGGTCA GAGGACAACC GGCGCACAGG CAACAAGGGC 
CTTCGGCTAA AAGAGAGTGG AGCCATCAAC ACCTCCCTGT TTGTCCTGGG CAAAGTGGTA 
GATGCGCTGA ATCAGGGCCT CCCTCGTGTA CCTTATCGGG ACAGCAAGCT CACTCGCCTA 
TTGCAGGACT CTCTGGGTGG CTCAGCCCAC AGTATCCTTA TTGCCAACAT TGCCCCTGAG 
AGACGCTTCT ACCTAGACAC AGTCTCCGCA CTCAACTTTG CTGCCAGGTC CAAGGAGGTG 
ATCAATCGGC CTTTTACCAA TGAGAGCCTG CAGCCTCATG CCTTGGGACC TGTTAAGCTG 
TCTCAGAAAG AATTGCTTGG TCCACCAGAG GCAAAGAGAG CCCGAGGCCC TGAGGAAGAG 
GAGATCGGGA GCCCTGAGCC CATGGCAGCT CCAGCCTCTG CCTCCCAGAA ACTCAGCCCC 
CTACAGAAGC TAAGCAGCAT GGACCCGGCC ATGCTGGAGC GCCTCCTCAG CTTGGACCGT 
CTGCTTGCCT CCCAGGGGAG CCAGGGGGCC CCTCTGTTGA GTACCCCAAA GCGAGAGCGG 
ATGGTGCTAA TGAAGACAGT GGAAGAGAAG GACCTAGAGA TTGAGAGGCT TAAGACGAAG 
CAAAAAGAAC TGGAGGCCAA GATGTTGGCC CAGAAGGCTG AGGAAAAGGA GAACCATTGT 
CCCACAATGC TCCGGCCCCT TTCACATCGC ACAGTCACAG GGGCAAAGCC CCTGAAAAAG 
GCTGTGGTGA TGCCCCTACA GCTAATTCAG GAGCAGGCAG CATCCCCAAA TGCCGAGATC 
CACATCCTGA AGAATAAAGG CCGGAAGAGA AAGCTGGAGT CCCTGGATGC CCTAGAGCCT 
GAGGAGAAGG CTGAGGACTG CTGGGAGCTA CAGATCAGCC CGGAGCTACT GGCTCATGGG 
CGCCAAAAAA TACTGGATCT GCTGAACGAA GGCTCAGCCC GAGATCTCCG CAGTCTTCAG 
CGCATTGGCC CGAAGAAGGC CCAGCTAATC GTGGGCTGGC GGGAGCTCCA CGGCCCCTTC 
AGCCAGGTGG AGGACCTGGA ACGCGTGGAG GGCATAACGG GGAAACAGAT GGAGTCCTTC 
CTGAAGGCAA ACATCCTGGG TCTCGCCGCC GGCCAGCGCT GTGGCGCCTC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243198.1
CDS	301..2094
Translation	MDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS

Target ORF information:

RefSeq Version	NM_001256269.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 22 (KIF22), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256269.1

ORF Insert Sequence:

ATGGACAGCT GCTCTCTAGA GATTGCTAAC TGGAGGAACC ACCAGGAGAC TCTCAAATAC 
CAGTTTGATG CCTTCTATGG GGAGAGGAGT ACTCAGCAGG ACATCTATGC AGGTTCAGTG 
CAGCCCATCC TAAGGCACTT GCTGGAAGGG CAGAATGCCA GTGTGCTTGC CTATGGACCC 
ACAGGAGCTG GGAAGACGCA CACAATGCTG GGCAGCCCAG AGCAACCTGG GGTGATCCCG 
CGGGCTCTCA TGGACCTCCT GCAGCTCACA AGGGAGGAGG GTGCCGAGGG CCGGCCATGG 
GCCCTTTCTG TCACCATGTC TTACCTAGAG ATCTACCAGG AGAAGGTATT AGACCTCCTG 
GACCCTGCTT CGGGAGACCT GGTAATCCGA GAAGACTGCC GGGGGAATAT CCTGATTCCG 
GGTCTCTCCC AGAAGCCCAT CAGTAGCTTT GCTGATTTTG AGCGGCACTT CCTGCCAGCC 
AGTCGAAATC GGACTGTAGG AGCCACCCGG CTCAACCAGC GCTCCTCCCG CAGTCATGCT 
GTGCTCCTGG TCAAGGTGGA CCAGCGGGAA CGTTTGGCCC CATTTCGCCA GCGAGAGGGA 
AAACTCTACC TGATTGACTT GGCTGGGTCA GAGGACAACC GGCGCACAGG CAACAAGGGC 
CTTCGGCTAA AAGAGAGTGG AGCCATCAAC ACCTCCCTGT TTGTCCTGGG CAAAGTGGTA 
GATGCGCTGA ATCAGGGCCT CCCTCGTGTA CCTTATCGGG ACAGCAAGCT CACTCGCCTA 
TTGCAGGACT CTCTGGGTGG CTCAGCCCAC AGTATCCTTA TTGCCAACAT TGCCCCTGAG 
AGACGCTTCT ACCTAGACAC AGTCTCCGCA CTCAACTTTG CTGCCAGGTC CAAGGAGGTG 
ATCAATCGGC CTTTTACCAA TGAGAGCCTG CAGCCTCATG CCTTGGGACC TGTTAAGCTG 
TCTCAGAAAG AATTGCTTGG TCCACCAGAG GCAAAGAGAG CCCGAGGCCC TGAGGAAGAG 
GAGATCGGGA GCCCTGAGCC CATGGCAGCT CCAGCCTCTG CCTCCCAGAA ACTCAGCCCC 
CTACAGAAGC TAAGCAGCAT GGACCCGGCC ATGCTGGAGC GCCTCCTCAG CTTGGACCGT 
CTGCTTGCCT CCCAGGGGAG CCAGGGGGCC CCTCTGTTGA GTACCCCAAA GCGAGAGCGG 
ATGGTGCTAA TGAAGACAGT GGAAGAGAAG GACCTAGAGA TTGAGAGGCT TAAGACGAAG 
CAAAAAGAAC TGGAGGCCAA GATGTTGGCC CAGAAGGCTG AGGAAAAGGA GAACCATTGT 
CCCACAATGC TCCGGCCCCT TTCACATCGC ACAGTCACAG GGGCAAAGCC CCTGAAAAAG 
GCTGTGGTGA TGCCCCTACA GCTAATTCAG GAGCAGGCAG CATCCCCAAA TGCCGAGATC 
CACATCCTGA AGAATAAAGG CCGGAAGAGA AAGCTGGAGT CCCTGGATGC CCTAGAGCCT 
GAGGAGAAGG CTGAGGACTG CTGGGAGCTA CAGATCAGCC CGGAGCTACT GGCTCATGGG 
CGCCAAAAAA TACTGGATCT GCTGAACGAA GGCTCAGCCC GAGATCTCCG CAGTCTTCAG 
CGCATTGGCC CGAAGAAGGC CCAGCTAATC GTGGGCTGGC GGGAGCTCCA CGGCCCCTTC 
AGCCAGGTGG AGGACCTGGA ACGCGTGGAG GGCATAACGG GGAAACAGAT GGAGTCCTTC 
CTGAAGGCAA ACATCCTGGG TCTCGCCGCC GGCCAGCGCT GTGGCGCCTC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIF22 ( NM_001256269.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243198.1 Homo sapiens kinesin family member 22 (KIF22), transcript variant 2, mRNA.

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CloneID	OHu11567
Clone ID Related Accession (Same CDS sequence)	NM_001256269.1 , NM_001256269.2 , NM_001256270.1
Accession Version	NM_001256269.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-14
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF22 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC370294.1, AK316389.1, AK223431.1 and BC028155.1. On Jun 2, 2019 this sequence version replaced NM_001256269.1. Transcript Variant: This variant (2) has an additional exon in the 5' region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus than isoform 1. Variants 2 and 3 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK316389.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END##

ATGGACAGCT GCTCTCTAGA GATTGCTAAC TGGAGGAACC ACCAGGAGAC TCTCAAATAC 
CAGTTTGATG CCTTCTATGG GGAGAGGAGT ACTCAGCAGG ACATCTATGC AGGTTCAGTG 
CAGCCCATCC TAAGGCACTT GCTGGAAGGG CAGAATGCCA GTGTGCTTGC CTATGGACCC 
ACAGGAGCTG GGAAGACGCA CACAATGCTG GGCAGCCCAG AGCAACCTGG GGTGATCCCG 
CGGGCTCTCA TGGACCTCCT GCAGCTCACA AGGGAGGAGG GTGCCGAGGG CCGGCCATGG 
GCCCTTTCTG TCACCATGTC TTACCTAGAG ATCTACCAGG AGAAGGTATT AGACCTCCTG 
GACCCTGCTT CGGGAGACCT GGTAATCCGA GAAGACTGCC GGGGGAATAT CCTGATTCCG 
GGTCTCTCCC AGAAGCCCAT CAGTAGCTTT GCTGATTTTG AGCGGCACTT CCTGCCAGCC 
AGTCGAAATC GGACTGTAGG AGCCACCCGG CTCAACCAGC GCTCCTCCCG CAGTCATGCT 
GTGCTCCTGG TCAAGGTGGA CCAGCGGGAA CGTTTGGCCC CATTTCGCCA GCGAGAGGGA 
AAACTCTACC TGATTGACTT GGCTGGGTCA GAGGACAACC GGCGCACAGG CAACAAGGGC 
CTTCGGCTAA AAGAGAGTGG AGCCATCAAC ACCTCCCTGT TTGTCCTGGG CAAAGTGGTA 
GATGCGCTGA ATCAGGGCCT CCCTCGTGTA CCTTATCGGG ACAGCAAGCT CACTCGCCTA 
TTGCAGGACT CTCTGGGTGG CTCAGCCCAC AGTATCCTTA TTGCCAACAT TGCCCCTGAG 
AGACGCTTCT ACCTAGACAC AGTCTCCGCA CTCAACTTTG CTGCCAGGTC CAAGGAGGTG 
ATCAATCGGC CTTTTACCAA TGAGAGCCTG CAGCCTCATG CCTTGGGACC TGTTAAGCTG 
TCTCAGAAAG AATTGCTTGG TCCACCAGAG GCAAAGAGAG CCCGAGGCCC TGAGGAAGAG 
GAGATCGGGA GCCCTGAGCC CATGGCAGCT CCAGCCTCTG CCTCCCAGAA ACTCAGCCCC 
CTACAGAAGC TAAGCAGCAT GGACCCGGCC ATGCTGGAGC GCCTCCTCAG CTTGGACCGT 
CTGCTTGCCT CCCAGGGGAG CCAGGGGGCC CCTCTGTTGA GTACCCCAAA GCGAGAGCGG 
ATGGTGCTAA TGAAGACAGT GGAAGAGAAG GACCTAGAGA TTGAGAGGCT TAAGACGAAG 
CAAAAAGAAC TGGAGGCCAA GATGTTGGCC CAGAAGGCTG AGGAAAAGGA GAACCATTGT 
CCCACAATGC TCCGGCCCCT TTCACATCGC ACAGTCACAG GGGCAAAGCC CCTGAAAAAG 
GCTGTGGTGA TGCCCCTACA GCTAATTCAG GAGCAGGCAG CATCCCCAAA TGCCGAGATC 
CACATCCTGA AGAATAAAGG CCGGAAGAGA AAGCTGGAGT CCCTGGATGC CCTAGAGCCT 
GAGGAGAAGG CTGAGGACTG CTGGGAGCTA CAGATCAGCC CGGAGCTACT GGCTCATGGG 
CGCCAAAAAA TACTGGATCT GCTGAACGAA GGCTCAGCCC GAGATCTCCG CAGTCTTCAG 
CGCATTGGCC CGAAGAAGGC CCAGCTAATC GTGGGCTGGC GGGAGCTCCA CGGCCCCTTC 
AGCCAGGTGG AGGACCTGGA ACGCGTGGAG GGCATAACGG GGAAACAGAT GGAGTCCTTC 
CTGAAGGCAA ACATCCTGGG TCTCGCCGCC GGCCAGCGCT GTGGCGCCTC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243198.1
CDS	263..2056
Translation	MDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS

Target ORF information:

RefSeq Version	NM_001256269.2
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 22 (KIF22), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256269.2

ORF Insert Sequence:

ATGGACAGCT GCTCTCTAGA GATTGCTAAC TGGAGGAACC ACCAGGAGAC TCTCAAATAC 
CAGTTTGATG CCTTCTATGG GGAGAGGAGT ACTCAGCAGG ACATCTATGC AGGTTCAGTG 
CAGCCCATCC TAAGGCACTT GCTGGAAGGG CAGAATGCCA GTGTGCTTGC CTATGGACCC 
ACAGGAGCTG GGAAGACGCA CACAATGCTG GGCAGCCCAG AGCAACCTGG GGTGATCCCG 
CGGGCTCTCA TGGACCTCCT GCAGCTCACA AGGGAGGAGG GTGCCGAGGG CCGGCCATGG 
GCCCTTTCTG TCACCATGTC TTACCTAGAG ATCTACCAGG AGAAGGTATT AGACCTCCTG 
GACCCTGCTT CGGGAGACCT GGTAATCCGA GAAGACTGCC GGGGGAATAT CCTGATTCCG 
GGTCTCTCCC AGAAGCCCAT CAGTAGCTTT GCTGATTTTG AGCGGCACTT CCTGCCAGCC 
AGTCGAAATC GGACTGTAGG AGCCACCCGG CTCAACCAGC GCTCCTCCCG CAGTCATGCT 
GTGCTCCTGG TCAAGGTGGA CCAGCGGGAA CGTTTGGCCC CATTTCGCCA GCGAGAGGGA 
AAACTCTACC TGATTGACTT GGCTGGGTCA GAGGACAACC GGCGCACAGG CAACAAGGGC 
CTTCGGCTAA AAGAGAGTGG AGCCATCAAC ACCTCCCTGT TTGTCCTGGG CAAAGTGGTA 
GATGCGCTGA ATCAGGGCCT CCCTCGTGTA CCTTATCGGG ACAGCAAGCT CACTCGCCTA 
TTGCAGGACT CTCTGGGTGG CTCAGCCCAC AGTATCCTTA TTGCCAACAT TGCCCCTGAG 
AGACGCTTCT ACCTAGACAC AGTCTCCGCA CTCAACTTTG CTGCCAGGTC CAAGGAGGTG 
ATCAATCGGC CTTTTACCAA TGAGAGCCTG CAGCCTCATG CCTTGGGACC TGTTAAGCTG 
TCTCAGAAAG AATTGCTTGG TCCACCAGAG GCAAAGAGAG CCCGAGGCCC TGAGGAAGAG 
GAGATCGGGA GCCCTGAGCC CATGGCAGCT CCAGCCTCTG CCTCCCAGAA ACTCAGCCCC 
CTACAGAAGC TAAGCAGCAT GGACCCGGCC ATGCTGGAGC GCCTCCTCAG CTTGGACCGT 
CTGCTTGCCT CCCAGGGGAG CCAGGGGGCC CCTCTGTTGA GTACCCCAAA GCGAGAGCGG 
ATGGTGCTAA TGAAGACAGT GGAAGAGAAG GACCTAGAGA TTGAGAGGCT TAAGACGAAG 
CAAAAAGAAC TGGAGGCCAA GATGTTGGCC CAGAAGGCTG AGGAAAAGGA GAACCATTGT 
CCCACAATGC TCCGGCCCCT TTCACATCGC ACAGTCACAG GGGCAAAGCC CCTGAAAAAG 
GCTGTGGTGA TGCCCCTACA GCTAATTCAG GAGCAGGCAG CATCCCCAAA TGCCGAGATC 
CACATCCTGA AGAATAAAGG CCGGAAGAGA AAGCTGGAGT CCCTGGATGC CCTAGAGCCT 
GAGGAGAAGG CTGAGGACTG CTGGGAGCTA CAGATCAGCC CGGAGCTACT GGCTCATGGG 
CGCCAAAAAA TACTGGATCT GCTGAACGAA GGCTCAGCCC GAGATCTCCG CAGTCTTCAG 
CGCATTGGCC CGAAGAAGGC CCAGCTAATC GTGGGCTGGC GGGAGCTCCA CGGCCCCTTC 
AGCCAGGTGG AGGACCTGGA ACGCGTGGAG GGCATAACGG GGAAACAGAT GGAGTCCTTC 
CTGAAGGCAA ACATCCTGGG TCTCGCCGCC GGCCAGCGCT GTGGCGCCTC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIF22 ( NM_001256270.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243199.1 Homo sapiens kinesin family member 22 (KIF22), transcript variant 3, mRNA.

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CloneID	OHu11567
Clone ID Related Accession (Same CDS sequence)	NM_001256269.1 , NM_001256269.2 , NM_001256270.1
Accession Version	NM_001256270.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-14
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF22 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009133.7, AK316050.1, BC004352.1, AK223431.1 and BC028155.1. Transcript Variant: This variant (3) has an alternate 5' exon, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus than isoform 1. Variants 2 and 3 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK316050.1, SRR1803611.234756.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END##

ATGGACAGCT GCTCTCTAGA GATTGCTAAC TGGAGGAACC ACCAGGAGAC TCTCAAATAC 
CAGTTTGATG CCTTCTATGG GGAGAGGAGT ACTCAGCAGG ACATCTATGC AGGTTCAGTG 
CAGCCCATCC TAAGGCACTT GCTGGAAGGG CAGAATGCCA GTGTGCTTGC CTATGGACCC 
ACAGGAGCTG GGAAGACGCA CACAATGCTG GGCAGCCCAG AGCAACCTGG GGTGATCCCG 
CGGGCTCTCA TGGACCTCCT GCAGCTCACA AGGGAGGAGG GTGCCGAGGG CCGGCCATGG 
GCCCTTTCTG TCACCATGTC TTACCTAGAG ATCTACCAGG AGAAGGTATT AGACCTCCTG 
GACCCTGCTT CGGGAGACCT GGTAATCCGA GAAGACTGCC GGGGGAATAT CCTGATTCCG 
GGTCTCTCCC AGAAGCCCAT CAGTAGCTTT GCTGATTTTG AGCGGCACTT CCTGCCAGCC 
AGTCGAAATC GGACTGTAGG AGCCACCCGG CTCAACCAGC GCTCCTCCCG CAGTCATGCT 
GTGCTCCTGG TCAAGGTGGA CCAGCGGGAA CGTTTGGCCC CATTTCGCCA GCGAGAGGGA 
AAACTCTACC TGATTGACTT GGCTGGGTCA GAGGACAACC GGCGCACAGG CAACAAGGGC 
CTTCGGCTAA AAGAGAGTGG AGCCATCAAC ACCTCCCTGT TTGTCCTGGG CAAAGTGGTA 
GATGCGCTGA ATCAGGGCCT CCCTCGTGTA CCTTATCGGG ACAGCAAGCT CACTCGCCTA 
TTGCAGGACT CTCTGGGTGG CTCAGCCCAC AGTATCCTTA TTGCCAACAT TGCCCCTGAG 
AGACGCTTCT ACCTAGACAC AGTCTCCGCA CTCAACTTTG CTGCCAGGTC CAAGGAGGTG 
ATCAATCGGC CTTTTACCAA TGAGAGCCTG CAGCCTCATG CCTTGGGACC TGTTAAGCTG 
TCTCAGAAAG AATTGCTTGG TCCACCAGAG GCAAAGAGAG CCCGAGGCCC TGAGGAAGAG 
GAGATCGGGA GCCCTGAGCC CATGGCAGCT CCAGCCTCTG CCTCCCAGAA ACTCAGCCCC 
CTACAGAAGC TAAGCAGCAT GGACCCGGCC ATGCTGGAGC GCCTCCTCAG CTTGGACCGT 
CTGCTTGCCT CCCAGGGGAG CCAGGGGGCC CCTCTGTTGA GTACCCCAAA GCGAGAGCGG 
ATGGTGCTAA TGAAGACAGT GGAAGAGAAG GACCTAGAGA TTGAGAGGCT TAAGACGAAG 
CAAAAAGAAC TGGAGGCCAA GATGTTGGCC CAGAAGGCTG AGGAAAAGGA GAACCATTGT 
CCCACAATGC TCCGGCCCCT TTCACATCGC ACAGTCACAG GGGCAAAGCC CCTGAAAAAG 
GCTGTGGTGA TGCCCCTACA GCTAATTCAG GAGCAGGCAG CATCCCCAAA TGCCGAGATC 
CACATCCTGA AGAATAAAGG CCGGAAGAGA AAGCTGGAGT CCCTGGATGC CCTAGAGCCT 
GAGGAGAAGG CTGAGGACTG CTGGGAGCTA CAGATCAGCC CGGAGCTACT GGCTCATGGG 
CGCCAAAAAA TACTGGATCT GCTGAACGAA GGCTCAGCCC GAGATCTCCG CAGTCTTCAG 
CGCATTGGCC CGAAGAAGGC CCAGCTAATC GTGGGCTGGC GGGAGCTCCA CGGCCCCTTC 
AGCCAGGTGG AGGACCTGGA ACGCGTGGAG GGCATAACGG GGAAACAGAT GGAGTCCTTC 
CTGAAGGCAA ACATCCTGGG TCTCGCCGCC GGCCAGCGCT GTGGCGCCTC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243199.1
CDS	389..2182
Translation	MDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS

Target ORF information:

RefSeq Version	NM_001256270.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 22 (KIF22), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256270.1

ORF Insert Sequence:

ATGGACAGCT GCTCTCTAGA GATTGCTAAC TGGAGGAACC ACCAGGAGAC TCTCAAATAC 
CAGTTTGATG CCTTCTATGG GGAGAGGAGT ACTCAGCAGG ACATCTATGC AGGTTCAGTG 
CAGCCCATCC TAAGGCACTT GCTGGAAGGG CAGAATGCCA GTGTGCTTGC CTATGGACCC 
ACAGGAGCTG GGAAGACGCA CACAATGCTG GGCAGCCCAG AGCAACCTGG GGTGATCCCG 
CGGGCTCTCA TGGACCTCCT GCAGCTCACA AGGGAGGAGG GTGCCGAGGG CCGGCCATGG 
GCCCTTTCTG TCACCATGTC TTACCTAGAG ATCTACCAGG AGAAGGTATT AGACCTCCTG 
GACCCTGCTT CGGGAGACCT GGTAATCCGA GAAGACTGCC GGGGGAATAT CCTGATTCCG 
GGTCTCTCCC AGAAGCCCAT CAGTAGCTTT GCTGATTTTG AGCGGCACTT CCTGCCAGCC 
AGTCGAAATC GGACTGTAGG AGCCACCCGG CTCAACCAGC GCTCCTCCCG CAGTCATGCT 
GTGCTCCTGG TCAAGGTGGA CCAGCGGGAA CGTTTGGCCC CATTTCGCCA GCGAGAGGGA 
AAACTCTACC TGATTGACTT GGCTGGGTCA GAGGACAACC GGCGCACAGG CAACAAGGGC 
CTTCGGCTAA AAGAGAGTGG AGCCATCAAC ACCTCCCTGT TTGTCCTGGG CAAAGTGGTA 
GATGCGCTGA ATCAGGGCCT CCCTCGTGTA CCTTATCGGG ACAGCAAGCT CACTCGCCTA 
TTGCAGGACT CTCTGGGTGG CTCAGCCCAC AGTATCCTTA TTGCCAACAT TGCCCCTGAG 
AGACGCTTCT ACCTAGACAC AGTCTCCGCA CTCAACTTTG CTGCCAGGTC CAAGGAGGTG 
ATCAATCGGC CTTTTACCAA TGAGAGCCTG CAGCCTCATG CCTTGGGACC TGTTAAGCTG 
TCTCAGAAAG AATTGCTTGG TCCACCAGAG GCAAAGAGAG CCCGAGGCCC TGAGGAAGAG 
GAGATCGGGA GCCCTGAGCC CATGGCAGCT CCAGCCTCTG CCTCCCAGAA ACTCAGCCCC 
CTACAGAAGC TAAGCAGCAT GGACCCGGCC ATGCTGGAGC GCCTCCTCAG CTTGGACCGT 
CTGCTTGCCT CCCAGGGGAG CCAGGGGGCC CCTCTGTTGA GTACCCCAAA GCGAGAGCGG 
ATGGTGCTAA TGAAGACAGT GGAAGAGAAG GACCTAGAGA TTGAGAGGCT TAAGACGAAG 
CAAAAAGAAC TGGAGGCCAA GATGTTGGCC CAGAAGGCTG AGGAAAAGGA GAACCATTGT 
CCCACAATGC TCCGGCCCCT TTCACATCGC ACAGTCACAG GGGCAAAGCC CCTGAAAAAG 
GCTGTGGTGA TGCCCCTACA GCTAATTCAG GAGCAGGCAG CATCCCCAAA TGCCGAGATC 
CACATCCTGA AGAATAAAGG CCGGAAGAGA AAGCTGGAGT CCCTGGATGC CCTAGAGCCT 
GAGGAGAAGG CTGAGGACTG CTGGGAGCTA CAGATCAGCC CGGAGCTACT GGCTCATGGG 
CGCCAAAAAA TACTGGATCT GCTGAACGAA GGCTCAGCCC GAGATCTCCG CAGTCTTCAG 
CGCATTGGCC CGAAGAAGGC CCAGCTAATC GTGGGCTGGC GGGAGCTCCA CGGCCCCTTC 
AGCCAGGTGG AGGACCTGGA ACGCGTGGAG GGCATAACGG GGAAACAGAT GGAGTCCTTC 
CTGAAGGCAA ACATCCTGGG TCTCGCCGCC GGCCAGCGCT GTGGCGCCTC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIF22 ( NM_007317.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_015556.1 Homo sapiens kinesin family member 22 (KIF22), transcript variant 1, mRNA.

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CloneID	OHu20210
Clone ID Related Accession (Same CDS sequence)	NM_007317.2 , NM_007317.3
Accession Version	NM_007317.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1998bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF22 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009133.7. This sequence is a reference standard in the RefSeqGene project. On Aug 13, 2019 this sequence version replaced NM_007317.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.110828.1, SRR1803617.234857.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGCGG GCGGCTCGAC GCAGCAGAGG CGACGCGAGA TGGCGGCAGC TTCAGCGGCG 
GCGATCTCAG GAGCTGGTCG CTGTCGGCTA AGCAAGATTG GAGCTACTCG TCGTCCACCT 
CCAGCTCGCG TAAGGGTGGC TGTGCGACTG CGGCCATTTG TGGATGGAAC AGCGGGAGCA 
AGTGATCCCC CCTGTGTGCG GGGCATGGAC AGCTGCTCTC TAGAGATTGC TAACTGGAGG 
AACCACCAGG AGACTCTCAA ATACCAGTTT GATGCCTTCT ATGGGGAGAG GAGTACTCAG 
CAGGACATCT ATGCAGGTTC AGTGCAGCCC ATCCTAAGGC ACTTGCTGGA AGGGCAGAAT 
GCCAGTGTGC TTGCCTATGG ACCCACAGGA GCTGGGAAGA CGCACACAAT GCTGGGCAGC 
CCAGAGCAAC CTGGGGTGAT CCCGCGGGCT CTCATGGACC TCCTGCAGCT CACAAGGGAG 
GAGGGTGCCG AGGGCCGGCC ATGGGCCCTT TCTGTCACCA TGTCTTACCT AGAGATCTAC 
CAGGAGAAGG TATTAGACCT CCTGGACCCT GCTTCGGGAG ACCTGGTAAT CCGAGAAGAC 
TGCCGGGGGA ATATCCTGAT TCCGGGTCTC TCCCAGAAGC CCATCAGTAG CTTTGCTGAT 
TTTGAGCGGC ACTTCCTGCC AGCCAGTCGA AATCGGACTG TAGGAGCCAC CCGGCTCAAC 
CAGCGCTCCT CCCGCAGTCA TGCTGTGCTC CTGGTCAAGG TGGACCAGCG GGAACGTTTG 
GCCCCATTTC GCCAGCGAGA GGGAAAACTC TACCTGATTG ACTTGGCTGG GTCAGAGGAC 
AACCGGCGCA CAGGCAACAA GGGCCTTCGG CTAAAAGAGA GTGGAGCCAT CAACACCTCC 
CTGTTTGTCC TGGGCAAAGT GGTAGATGCG CTGAATCAGG GCCTCCCTCG TGTACCTTAT 
CGGGACAGCA AGCTCACTCG CCTATTGCAG GACTCTCTGG GTGGCTCAGC CCACAGTATC 
CTTATTGCCA ACATTGCCCC TGAGAGACGC TTCTACCTAG ACACAGTCTC CGCACTCAAC 
TTTGCTGCCA GGTCCAAGGA GGTGATCAAT CGGCCTTTTA CCAATGAGAG CCTGCAGCCT 
CATGCCTTGG GACCTGTTAA GCTGTCTCAG AAAGAATTGC TTGGTCCACC AGAGGCAAAG 
AGAGCCCGAG GCCCTGAGGA AGAGGAGATC GGGAGCCCTG AGCCCATGGC AGCTCCAGCC 
TCTGCCTCCC AGAAACTCAG CCCCCTACAG AAGCTAAGCA GCATGGACCC GGCCATGCTG 
GAGCGCCTCC TCAGCTTGGA CCGTCTGCTT GCCTCCCAGG GGAGCCAGGG GGCCCCTCTG 
TTGAGTACCC CAAAGCGAGA GCGGATGGTG CTAATGAAGA CAGTGGAAGA GAAGGACCTA 
GAGATTGAGA GGCTTAAGAC GAAGCAAAAA GAACTGGAGG CCAAGATGTT GGCCCAGAAG 
GCTGAGGAAA AGGAGAACCA TTGTCCCACA ATGCTCCGGC CCCTTTCACA TCGCACAGTC 
ACAGGGGCAA AGCCCCTGAA AAAGGCTGTG GTGATGCCCC TACAGCTAAT TCAGGAGCAG 
GCAGCATCCC CAAATGCCGA GATCCACATC CTGAAGAATA AAGGCCGGAA GAGAAAGCTG 
GAGTCCCTGG ATGCCCTAGA GCCTGAGGAG AAGGCTGAGG ACTGCTGGGA GCTACAGATC 
AGCCCGGAGC TACTGGCTCA TGGGCGCCAA AAAATACTGG ATCTGCTGAA CGAAGGCTCA 
GCCCGAGATC TCCGCAGTCT TCAGCGCATT GGCCCGAAGA AGGCCCAGCT AATCGTGGGC 
TGGCGGGAGC TCCACGGCCC CTTCAGCCAG GTGGAGGACC TGGAACGCGT GGAGGGCATA 
ACGGGGAAAC AGATGGAGTC CTTCCTGAAG GCAAACATCC TGGGTCTCGC CGCCGGCCAG 
CGCTGTGGCG CCTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_015556.1
CDS	10..2007
Translation	MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS

Target ORF information:

RefSeq Version	NM_007317.3
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 22 (KIF22), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007317.3

ORF Insert Sequence:

ATGGCCGCGG GCGGCTCGAC GCAGCAGAGG CGACGCGAGA TGGCGGCAGC TTCAGCGGCG 
GCGATCTCAG GAGCTGGTCG CTGTCGGCTA AGCAAGATTG GAGCTACTCG TCGTCCACCT 
CCAGCTCGCG TAAGGGTGGC TGTGCGACTG CGGCCATTTG TGGATGGAAC AGCGGGAGCA 
AGTGATCCCC CCTGTGTGCG GGGCATGGAC AGCTGCTCTC TAGAGATTGC TAACTGGAGG 
AACCACCAGG AGACTCTCAA ATACCAGTTT GATGCCTTCT ATGGGGAGAG GAGTACTCAG 
CAGGACATCT ATGCAGGTTC AGTGCAGCCC ATCCTAAGGC ACTTGCTGGA AGGGCAGAAT 
GCCAGTGTGC TTGCCTATGG ACCCACAGGA GCTGGGAAGA CGCACACAAT GCTGGGCAGC 
CCAGAGCAAC CTGGGGTGAT CCCGCGGGCT CTCATGGACC TCCTGCAGCT CACAAGGGAG 
GAGGGTGCCG AGGGCCGGCC ATGGGCCCTT TCTGTCACCA TGTCTTACCT AGAGATCTAC 
CAGGAGAAGG TATTAGACCT CCTGGACCCT GCTTCGGGAG ACCTGGTAAT CCGAGAAGAC 
TGCCGGGGGA ATATCCTGAT TCCGGGTCTC TCCCAGAAGC CCATCAGTAG CTTTGCTGAT 
TTTGAGCGGC ACTTCCTGCC AGCCAGTCGA AATCGGACTG TAGGAGCCAC CCGGCTCAAC 
CAGCGCTCCT CCCGCAGTCA TGCTGTGCTC CTGGTCAAGG TGGACCAGCG GGAACGTTTG 
GCCCCATTTC GCCAGCGAGA GGGAAAACTC TACCTGATTG ACTTGGCTGG GTCAGAGGAC 
AACCGGCGCA CAGGCAACAA GGGCCTTCGG CTAAAAGAGA GTGGAGCCAT CAACACCTCC 
CTGTTTGTCC TGGGCAAAGT GGTAGATGCG CTGAATCAGG GCCTCCCTCG TGTACCTTAT 
CGGGACAGCA AGCTCACTCG CCTATTGCAG GACTCTCTGG GTGGCTCAGC CCACAGTATC 
CTTATTGCCA ACATTGCCCC TGAGAGACGC TTCTACCTAG ACACAGTCTC CGCACTCAAC 
TTTGCTGCCA GGTCCAAGGA GGTGATCAAT CGGCCTTTTA CCAATGAGAG CCTGCAGCCT 
CATGCCTTGG GACCTGTTAA GCTGTCTCAG AAAGAATTGC TTGGTCCACC AGAGGCAAAG 
AGAGCCCGAG GCCCTGAGGA AGAGGAGATC GGGAGCCCTG AGCCCATGGC AGCTCCAGCC 
TCTGCCTCCC AGAAACTCAG CCCCCTACAG AAGCTAAGCA GCATGGACCC GGCCATGCTG 
GAGCGCCTCC TCAGCTTGGA CCGTCTGCTT GCCTCCCAGG GGAGCCAGGG GGCCCCTCTG 
TTGAGTACCC CAAAGCGAGA GCGGATGGTG CTAATGAAGA CAGTGGAAGA GAAGGACCTA 
GAGATTGAGA GGCTTAAGAC GAAGCAAAAA GAACTGGAGG CCAAGATGTT GGCCCAGAAG 
GCTGAGGAAA AGGAGAACCA TTGTCCCACA ATGCTCCGGC CCCTTTCACA TCGCACAGTC 
ACAGGGGCAA AGCCCCTGAA AAAGGCTGTG GTGATGCCCC TACAGCTAAT TCAGGAGCAG 
GCAGCATCCC CAAATGCCGA GATCCACATC CTGAAGAATA AAGGCCGGAA GAGAAAGCTG 
GAGTCCCTGG ATGCCCTAGA GCCTGAGGAG AAGGCTGAGG ACTGCTGGGA GCTACAGATC 
AGCCCGGAGC TACTGGCTCA TGGGCGCCAA AAAATACTGG ATCTGCTGAA CGAAGGCTCA 
GCCCGAGATC TCCGCAGTCT TCAGCGCATT GGCCCGAAGA AGGCCCAGCT AATCGTGGGC 
TGGCGGGAGC TCCACGGCCC CTTCAGCCAG GTGGAGGACC TGGAACGCGT GGAGGGCATA 
ACGGGGAAAC AGATGGAGTC CTTCCTGAAG GCAAACATCC TGGGTCTCGC CGCCGGCCAG 
CGCTGTGGCG CCTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIF22 ( XM_024450270.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306038.1 Homo sapiens kinesin family member 22 (KIF22), transcript variant X1, mRNA.

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CloneID	OHu104139
Clone ID Related Accession (Same CDS sequence)	XM_024450270.1
Accession Version	XM_024450270.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2172bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF22 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGCGG GCGGCTCGAC GCAGCAGAGG CGACGCGAGA TGGCGGCAGC TTCAGCGGCG 
GCGATCTCAG GAGCTGGTCG CTGTCGGCTA AGCAAGATTG GAGCTACTCG TCGTCCACCT 
CCAGCTCGCG TAAGGGTGGC TGTGCGACTG CGGCCATTTG TGGATGGAAC AGCGGGAGCA 
AGTGATCCCC CCTGTGTGCG GGGCATGGAC AGCTGCTCTC TAGAGATTGC TAACTGGAGG 
AACCACCAGG AGACTCTCAA ATACCAGTTT GATGCCTTCT ATGGGGAGAG GAGTACTCAG 
CAGGACATCT ATGCAGGTTC AGTGCAGCCC ATCCTAAGGC ACTTGCTGGA AGGGCAGAAT 
GCCAGTGTGC TTGCCTATGG ACCCACAGGA GCTGGGAAGA CGCACACAAT GCTGGGCAGC 
CCAGAGCAAC CTGGGGTGAT CCCGCGGGCT CTCATGGACC TCCTGCAGCT CACAAGGGAG 
GAGGGTGCCG AGGGCCGGCC ATGGGCCCTT TCTGTCACCA TGTCTTACCT AGAGATCTAC 
CAGGAGAAGG TATTAGACCT CCTGGACCCT GCTTCGGGAG ACCTGGTAAT CCGAGAAGAC 
TGCCGGGGGA ATATCCTGAT TCCGGGTCTC TCCCAGAAGC CCATCAGTAG CTTTGCTGAT 
TTTGAGCGGC ACTTCCTGCC AGCCAGTCGA AATCGGACTG TAGGAGCCAC CCGGCTCAAC 
CAGCGCTCCT CCCGCAGTCA TGCTGTGCTC CTGGTCAAGG TGGACCAGCG GGAACGTTTG 
GCCCCATTTC GCCAGCGAGA GGGAAAACTC TACCTGATTG ACTTGGCTGG GTCAGAGGAC 
AACCGGCGCA CAGGCAACAA GGGCCTTCGG CTAAAAGAGA GTGGAGCCAT CAACACCTCC 
CTGTTTGTCC TGGGCAAAGT GGTAGATGCG CTGAATCAGG GCCTCCCTCG TGTACCTTAT 
CGGGACAGCA AGCTCACTCG CCTATTGCAG GACTCTCTGG GTGGCTCAGC CCACAGTATC 
CTTATTGCCA ACATTGCCCC TGAGAGACGC TTCTACCTAG ACACAGTCTC CGCACTCAAC 
TTTGCTGCCA GGTCCAAGGA GGTGATCAAT CGGCCTTTTA CCAATGAGAG CCTGCAGCCT 
CATGCCTTGG GACCTGTTAA GCTGTCTCAG AAAGAATTGC TTGGTCCACC AGAGGCAAAG 
AGAGCCCGAG GCCCTGAGGA AGAGGAGATC GGGAGCCCTG AGCCCATGGC AGCTCCAGCC 
TCTGCCTCCC AGAAACTCAG CCCCCTACAG AAGCTAAGCA GCATGGACCC GGCCATGCTG 
GAGCGCCTCC TCAGCTTGGA CCGTCTGCTT GCCTCCCAGG GGAGCCAGGG GGCCCCTCTG 
TTGAGTACCC CAAAGCGAGA GCGGATGGTG CTAATGAAGA CAGTGGAAGA GAAGGACCTA 
GAGATTGAGA GGCTTAAGAC GAAGCAAAAA GAACTGGAGG CCAAGATGTT GGCCCAGAAG 
GCTGAGGAAA AGGAGAACCA TTGTCCCACA ATGCTCCGGC CCCTTTCACA TCGCACAGTC 
ACAGGGGCAA AGCCCCTGAA AAAGGCTGTG GTGATGCCCC TACAGCTAAT TCAGGAGCAG 
GCAGCATCCC CAAATGCCGA GATCCACATC CTGAAGAATA AAGGCCGGAA GAGAAAGCTG 
GAGTCCCTGG ATGCCCTAGA GCCTGAGGAG AAGGCTGAGG ACTGCTGGGA GCTACAGATC 
AGCCCGGAGC TACTGGCTCA TGGGCGCCAA AAAATACTGG ATCTGCTGAA CGAAGGCTCA 
GCCCGAGATC TCCGCAGTCT TCAGCGCATT GGCCCGAAGA AGGCCCAGCT AATCGTGGGC 
TGGCGGGAGC TCCACGGCCC CTTCAGCCAG GTAGCAGCCC ACTGGACTGG GGGAGGGCGG 
GGGCGGGGGA GACCGGGTAC CCCCGAGACC CTGTCCCCTA TCGATCCTGT CCCGCCAGGT 
GGAGGACCTG GAACGCGTGG AGGGCATAAC GGGGAAACAG ATGGAGTCCT TCCTGAAGGC 
AAACATCCTG GGTCTCGCCG CCGGCCAGCG CTGTGGCGCC TCCTGACCGT CGTCTCCTCA 
CTCCGCCTTT TCAAATTTTT GTATAACCCC GTGTTGTGTA AATACAGTTT TTGCTCCGGT 
GCTTCCGCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306038.1
CDS	27..2198
Translation	MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVAAHWTGGGRGRGRPGTPETLSPIDPVPPGGGPGTRGGHNGETDGVLPEGKHPGSRRRPALWRLLTVVSSLRLFKFLYNPVLCKYSFCSGASA

Target ORF information:

RefSeq Version	XM_024450270.1
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 22 (KIF22), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450270.1

ORF Insert Sequence:

ATGGCCGCGG GCGGCTCGAC GCAGCAGAGG CGACGCGAGA TGGCGGCAGC TTCAGCGGCG 
GCGATCTCAG GAGCTGGTCG CTGTCGGCTA AGCAAGATTG GAGCTACTCG TCGTCCACCT 
CCAGCTCGCG TAAGGGTGGC TGTGCGACTG CGGCCATTTG TGGATGGAAC AGCGGGAGCA 
AGTGATCCCC CCTGTGTGCG GGGCATGGAC AGCTGCTCTC TAGAGATTGC TAACTGGAGG 
AACCACCAGG AGACTCTCAA ATACCAGTTT GATGCCTTCT ATGGGGAGAG GAGTACTCAG 
CAGGACATCT ATGCAGGTTC AGTGCAGCCC ATCCTAAGGC ACTTGCTGGA AGGGCAGAAT 
GCCAGTGTGC TTGCCTATGG ACCCACAGGA GCTGGGAAGA CGCACACAAT GCTGGGCAGC 
CCAGAGCAAC CTGGGGTGAT CCCGCGGGCT CTCATGGACC TCCTGCAGCT CACAAGGGAG 
GAGGGTGCCG AGGGCCGGCC ATGGGCCCTT TCTGTCACCA TGTCTTACCT AGAGATCTAC 
CAGGAGAAGG TATTAGACCT CCTGGACCCT GCTTCGGGAG ACCTGGTAAT CCGAGAAGAC 
TGCCGGGGGA ATATCCTGAT TCCGGGTCTC TCCCAGAAGC CCATCAGTAG CTTTGCTGAT 
TTTGAGCGGC ACTTCCTGCC AGCCAGTCGA AATCGGACTG TAGGAGCCAC CCGGCTCAAC 
CAGCGCTCCT CCCGCAGTCA TGCTGTGCTC CTGGTCAAGG TGGACCAGCG GGAACGTTTG 
GCCCCATTTC GCCAGCGAGA GGGAAAACTC TACCTGATTG ACTTGGCTGG GTCAGAGGAC 
AACCGGCGCA CAGGCAACAA GGGCCTTCGG CTAAAAGAGA GTGGAGCCAT CAACACCTCC 
CTGTTTGTCC TGGGCAAAGT GGTAGATGCG CTGAATCAGG GCCTCCCTCG TGTACCTTAT 
CGGGACAGCA AGCTCACTCG CCTATTGCAG GACTCTCTGG GTGGCTCAGC CCACAGTATC 
CTTATTGCCA ACATTGCCCC TGAGAGACGC TTCTACCTAG ACACAGTCTC CGCACTCAAC 
TTTGCTGCCA GGTCCAAGGA GGTGATCAAT CGGCCTTTTA CCAATGAGAG CCTGCAGCCT 
CATGCCTTGG GACCTGTTAA GCTGTCTCAG AAAGAATTGC TTGGTCCACC AGAGGCAAAG 
AGAGCCCGAG GCCCTGAGGA AGAGGAGATC GGGAGCCCTG AGCCCATGGC AGCTCCAGCC 
TCTGCCTCCC AGAAACTCAG CCCCCTACAG AAGCTAAGCA GCATGGACCC GGCCATGCTG 
GAGCGCCTCC TCAGCTTGGA CCGTCTGCTT GCCTCCCAGG GGAGCCAGGG GGCCCCTCTG 
TTGAGTACCC CAAAGCGAGA GCGGATGGTG CTAATGAAGA CAGTGGAAGA GAAGGACCTA 
GAGATTGAGA GGCTTAAGAC GAAGCAAAAA GAACTGGAGG CCAAGATGTT GGCCCAGAAG 
GCTGAGGAAA AGGAGAACCA TTGTCCCACA ATGCTCCGGC CCCTTTCACA TCGCACAGTC 
ACAGGGGCAA AGCCCCTGAA AAAGGCTGTG GTGATGCCCC TACAGCTAAT TCAGGAGCAG 
GCAGCATCCC CAAATGCCGA GATCCACATC CTGAAGAATA AAGGCCGGAA GAGAAAGCTG 
GAGTCCCTGG ATGCCCTAGA GCCTGAGGAG AAGGCTGAGG ACTGCTGGGA GCTACAGATC 
AGCCCGGAGC TACTGGCTCA TGGGCGCCAA AAAATACTGG ATCTGCTGAA CGAAGGCTCA 
GCCCGAGATC TCCGCAGTCT TCAGCGCATT GGCCCGAAGA AGGCCCAGCT AATCGTGGGC 
TGGCGGGAGC TCCACGGCCC CTTCAGCCAG GTAGCAGCCC ACTGGACTGG GGGAGGGCGG 
GGGCGGGGGA GACCGGGTAC CCCCGAGACC CTGTCCCCTA TCGATCCTGT CCCGCCAGGT 
GGAGGACCTG GAACGCGTGG AGGGCATAAC GGGGAAACAG ATGGAGTCCT TCCTGAAGGC 
AAACATCCTG GGTCTCGCCG CCGGCCAGCG CTGTGGCGCC TCCTGACCGT CGTCTCCTCA 
CTCCGCCTTT TCAAATTTTT GTATAACCCC GTGTTGTGTA AATACAGTTT TTGCTCCGGT 
GCTTCCGCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules.
Nature communications66447(2015 Mar)
Iemura K,Tanaka K

Inhibition of KIF22 suppresses cancer cell proliferation by delaying mitotic exit through upregulating CDC25C expression.
Carcinogenesis35(6)1416-25(2014 Jun)
Yu Y,Wang XY,Sun L,Wang YL,Wan YF,Li XQ,Feng YM

Seventy-five genetic loci influencing the human red blood cell.
Nature492(7429)369-75(2012 Dec)
van der Harst P,Zhang W,Mateo Leach I,Rendon A,Verweij N,Sehmi J,Paul DS,Elling U,Allayee H,Li X,Radhakrishnan A,Tan ST,Voss K,Weichenberger CX,Albers CA,Al-Hussani A,Asselbergs FW,Ciullo M,Danjou F,Dina C,Esko T,Evans DM,Franke L,G?gele M,Hartiala J,Hersch M,Holm H,Hottenga JJ,Kanoni S,Kleber ME,Lagou V,Langenberg C,Lopez LM,Lyytik?inen LP,Melander O,Murgia F,Nolte IM,O'Reilly PF,Padmanabhan S,Parsa A,Pirastu N,Porcu E,Portas L,Prokopenko I,Ried JS,Shin SY,Tang CS,Teumer A,Traglia M,Ulivi S,Westra HJ,Yang J,Zhao JH,Anni F,Abdellaoui A,Attwood A,Balkau B,Bandinelli S,Bastardot F,Benyamin B,Boehm BO,Cookson WO,Das D,de Bakker PI,de Boer RA,de Geus EJ,de Moor MH,Dimitriou M,Domingues FS,D?ring A,Engstr?m G,Eyjolfsson GI,Ferrucci L,Fischer K,Galanello R,Garner SF,Genser B,Gibson QD,Girotto G,Gudbjartsson DF,Harris SE,Hartikainen AL,Hastie CE,Hedblad B,Illig T,Jolley J,K?h?nen M,Kema IP,Kemp JP,Liang L,Lloyd-Jones H,Loos RJ,Meacham S,Medland SE,Meisinger C,Memari Y,Mihailov E,Miller K,Moffatt MF,Nauck M,Novatchkova M,Nutile T,Olafsson I,Onundarson PT,Parracciani D,Penninx BW,Perseu L,Piga A,Pistis G,Pouta A,Puc U,Raitakari O,Ring SM,Robino A,Ruggiero D,Ruokonen A,Saint-Pierre A,Sala C,Salumets A,Sambrook J,Schepers H,Schmidt CO,Sillj? HH,Sladek R,Smit JH,Starr JM,Stephens J,Sulem P,Tanaka T,Thorsteinsdottir U,Tragante V,van Gilst WH,van Pelt LJ,van Veldhuisen DJ,V?lker U,Whitfield JB,Willemsen G,Winkelmann BR,Wirnsberger G,Algra A,Cucca F,d'Adamo AP,Danesh J,Deary IJ,Dominiczak AF,Elliott P,Fortina P,Froguel P,Gasparini P,Greinacher A,Hazen SL,Jarvelin MR,Khaw KT,Lehtim?ki T,Maerz W,Martin NG,Metspalu A,Mitchell BD,Montgomery GW,Moore C,Navis G,Pirastu M,Pramstaller PP,Ramirez-Solis R,Schadt E,Scott J,Shuldiner AR,Smith GD,Smith JG,Snieder H,Sorice R,Spector TD,Stefansson K,Stumvoll M,Tang WH,Toniolo D,T?njes A,Visscher PM,Vollenweider P,Wareham NJ,Wolffenbuttel BH,Boomsma DI,Beckmann JS,Dedoussis GV,Deloukas P,Ferreira MA,Sanna S,Uda M,Hicks AA,Penninger JM,Gieger C,Kooner JS,Ouwehand WH,Soranzo N,Chambers JC

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KIF22 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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