KLRC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KLRC1
Entrez Gene ID	3821
Full Name	killer cell lectin like receptor C1
Synonyms	CD159A,NKG2,NKG2A
General protein information	Preferred Names killer cell lectin like receptor C1 Names NKG2-A/NKG2-B type II integral membrane protein C-lectin type II protein CD159 antigen-like family member A NK cell receptor A NKG2-1/B activating NK receptor NKG2-A/B type II integral membrane protein NKG2-A/B-activating NK receptor killer cell lectin-like receptor subfamily C, member 1 natural killer cell lectin natural killer group protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.2
Summary	Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015].
Disorder MIM:	161555

mRNA and Protein(s)

mRNA	Protein	Name
NM_002259.5	NP_002250.2	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A
NM_213657.2	NP_998822.1	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-B
NM_007328.3	NP_015567.1	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-B
NM_213658.2	NP_998823.1	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A
XM_024448973.1	XP_024304741.1	NKG2-A/NKG2-B type II integral membrane protein isoform X1
NM_002259.4	NP_002250.1	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A
NM_007328.4	NP_015567.2	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-B
NM_001304448.1	NP_001291377.1	NKG2-A/NKG2-B type II integral membrane protein isoform C

Pathways from BioSystems

Homologies

Homo sapiens (human)	KLRC1	NP_002250.1
	KLRC1	NP_001028001.1
Bos taurus (cattle)	LOC101904048	XP_005207090.1
Bos taurus (cattle)	LOC100140174	XP_003586165.1
Pan troglodytes (chimpanzee)	KLRC1	NP_001009048.2
Bos taurus (cattle)	LOC513869	XP_002687840.1
Bos taurus (cattle)	LOC100139049	XP_003586167.1
Rattus norvegicus (Norway rat)	LOC100910089	XP_006237173.1
Bos taurus (cattle)	NKG2C	NP_001091632.1
Bos taurus (cattle)	LOC100847738	XP_003586171.1
Mus musculus (house mouse)	Klrc1	NP_001129540.1
Rattus norvegicus (Norway rat)	Klrc1	NP_001032518.1
Bos taurus (cattle)	LOC100336869	XP_002687846.1
Bos taurus (cattle)	LOC788694	XP_003586164.1
Bos taurus (cattle)	KLRC1	NP_001162059.1

Gene Ontology
Bibliography

Related articles in PubMed

Natural Killer Group 2A Expressed on Both Peripheral CD3
Yi RT, Niu YH, Liu HL, Zhang TY, Yang YC, Zhang Y, Yin DL, Chen TY, Zhao YR
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research36(12)689-697(2016 Dec)

The Activating NKG2C Receptor Is Significantly Reduced in NK Cells after Allogeneic Stem Cell Transplantation in Patients with Severe Graft-versus-Host Disease.
Kordelas L, Steckel NK, Horn PA, Beelen DW, Rebmann V
International journal of molecular sciences17(11)(2016 Oct)

Up-regulation of NKG2A inhibitory receptor on circulating NK cells contributes to transfusion-induced immunodepression in patients with ?-thalassemia major.
Zou Y, Song ZX, Lu Y, Liang XL, Yuan Q, Liao SH, Bao JJ
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban36(4)509-13(2016 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Compared with NKG2D, NKG2A expressed on both peripheral CD3-CD56+NK cells and CD3+CD8+T cells plays a more pivotal negative regulatory role in the progression of HBV-related ACLF.
Title: Natural Killer Group 2A Expressed on Both Peripheral CD3

Collectively, these results provide evidence for the first time that CD94/NKG2C is involved in chronic graft-versus-host disease prevention
Title: The Activating NKG2C Receptor Is Significantly Reduced in NK Cells after Allogeneic Stem Cell Transplantation in Patients with Severe Graft-versus-Host Disease.

These results indicate NKG2A inhibitory receptor may play a key role in transfusion-induced immunodepression of NK cells in patients with b-thalassemia major
Title: Up-regulation of NKG2A inhibitory receptor on circulating NK cells contributes to transfusion-induced immunodepression in patients with ?-thalassemia major.

NK cell maturation to CD56(dim) subset associated with high levels of NCRs overrides the inhibitory effect of NKG2A and recovers impaired NK cell cytolytic potential after allogeneic hematopoietic stem cell transplantation.
Title: NK cell maturation to CD56(dim) subset associated with high levels of NCRs overrides the inhibitory effect of NKG2A and recovers impaired NK cell cytolytic potential after allogeneic hematopoietic stem cell transplantation.

Coengagement of inhibitory receptors, either KIR2DL1 or CD94-NKG2A, did not inhibit phosphorylation of Stat5 but inhibited selectively phosphorylation of Akt and S6 ribosomal protein.
Title: NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors.

The following KLRC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KLRC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08654	NM_007328.3 Latest version!	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08654	NM_213657.2 Latest version!	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08711	NM_002259.4 Latest version!	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08711	NM_213658.2 Latest version!	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu58640	NM_001304448.1 Latest version!	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu108644	NM_002259.5 Latest version!	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu108649	NM_007328.4 Latest version!	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu103723	XM_024448973.1 Latest version!	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KLRC1 ( NM_213657.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_998822.1 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu08654
Clone ID Related Accession (Same CDS sequence)	NM_213657.2 , NM_007328.3
Accession Version	NM_213657.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC012550.1, AC068775.52 and BC053840.1. On Jan 5, 2010 this sequence version replaced NM_213657.1. Transcript Variant: This variant (4) differs in the 5' UTR and lacks an in-frame coding exon compared to variant 1. The resulting isoform (NKG2-B) is shorter compared to isoform NKG2-A. Variants 2 and 4 encode the same isoform (NKG2-B). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012550.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCACGTCA TTGTGGCCAT 
TGTCCTGAGG AGTGGATTAC ATATTCCAAC AGTTGTTACT ACATTGGTAA GGAAAGAAGA 
ACTTGGGAAG AGAGTTTGCT GGCCTGTACT TCGAAGAACT CCAGTCTGCT TTCTATAGAT 
AATGAAGAAG AAATGAAATT TCTGTCCATC ATTTCACCAT CCTCATGGAT TGGTGTGTTT 
CGTAACAGCA GTCATCATCC ATGGGTGACA ATGAATGGTT TGGCTTTCAA ACATGAGATA 
AAAGACTCAG ATAATGCTGA ACTTAACTGT GCAGTGCTAC AAGTAAATCG ACTTAAATCA 
GCCCAGTGTG GATCTTCAAT AATATATCAT TGTAAGCATA AGCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998822.1
CDS	389..1036
Translation	MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSRHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL

Target ORF information:

RefSeq Version	NM_213657.2
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213657.2

ORF Insert Sequence:

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCACGTCA TTGTGGCCAT 
TGTCCTGAGG AGTGGATTAC ATATTCCAAC AGTTGTTACT ACATTGGTAA GGAAAGAAGA 
ACTTGGGAAG AGAGTTTGCT GGCCTGTACT TCGAAGAACT CCAGTCTGCT TTCTATAGAT 
AATGAAGAAG AAATGAAATT TCTGTCCATC ATTTCACCAT CCTCATGGAT TGGTGTGTTT 
CGTAACAGCA GTCATCATCC ATGGGTGACA ATGAATGGTT TGGCTTTCAA ACATGAGATA 
AAAGACTCAG ATAATGCTGA ACTTAACTGT GCAGTGCTAC AAGTAAATCG ACTTAAATCA 
GCCCAGTGTG GATCTTCAAT AATATATCAT TGTAAGCATA AGCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLRC1 ( NM_007328.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_015567.1 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08654
Clone ID Related Accession (Same CDS sequence)	NM_213657.2 , NM_007328.3
Accession Version	NM_007328.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-07-20
Organism	Homo sapiens(human)
Product	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB464226.1, X54868.1 and BC053840.1. On or before Aug 31, 2013 this sequence version replaced XM_005253361.1, NM_007328.2. Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. The resulting isoform (NKG2-B) is shorter compared to isoform NKG2-A. Variants 2 and 4 encode the same isoform (NKG-2B). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X54868.1, ERR279826.2936.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCACGTCA TTGTGGCCAT 
TGTCCTGAGG AGTGGATTAC ATATTCCAAC AGTTGTTACT ACATTGGTAA GGAAAGAAGA 
ACTTGGGAAG AGAGTTTGCT GGCCTGTACT TCGAAGAACT CCAGTCTGCT TTCTATAGAT 
AATGAAGAAG AAATGAAATT TCTGTCCATC ATTTCACCAT CCTCATGGAT TGGTGTGTTT 
CGTAACAGCA GTCATCATCC ATGGGTGACA ATGAATGGTT TGGCTTTCAA ACATGAGATA 
AAAGACTCAG ATAATGCTGA ACTTAACTGT GCAGTGCTAC AAGTAAATCG ACTTAAATCA 
GCCCAGTGTG GATCTTCAAT AATATATCAT TGTAAGCATA AGCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_015567.1
CDS	215..862
Translation	MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSRHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL

Target ORF information:

RefSeq Version	NM_007328.3
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007328.3

ORF Insert Sequence:

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCACGTCA TTGTGGCCAT 
TGTCCTGAGG AGTGGATTAC ATATTCCAAC AGTTGTTACT ACATTGGTAA GGAAAGAAGA 
ACTTGGGAAG AGAGTTTGCT GGCCTGTACT TCGAAGAACT CCAGTCTGCT TTCTATAGAT 
AATGAAGAAG AAATGAAATT TCTGTCCATC ATTTCACCAT CCTCATGGAT TGGTGTGTTT 
CGTAACAGCA GTCATCATCC ATGGGTGACA ATGAATGGTT TGGCTTTCAA ACATGAGATA 
AAAGACTCAG ATAATGCTGA ACTTAACTGT GCAGTGCTAC AAGTAAATCG ACTTAAATCA 
GCCCAGTGTG GATCTTCAAT AATATATCAT TGTAAGCATA AGCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLRC1 ( NM_213658.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_998823.1 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08711
Clone ID Related Accession (Same CDS sequence)	NM_213658.2 , NM_002259.4
Accession Version	NM_213658.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC012550.1, AC068775.52 and BC053840.1. On Jan 5, 2010 this sequence version replaced NM_213658.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3 encode the same isoform (NKG2-A). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC053840.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTGTAAG CATAAGCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998823.1
CDS	389..1090
Translation	MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL

Target ORF information:

RefSeq Version	NM_213658.2
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213658.2

ORF Insert Sequence:

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTGTAAG CATAAGCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLRC1 ( NM_002259.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002250.1 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08711
Clone ID Related Accession (Same CDS sequence)	NM_213658.2 , NM_002259.4
Accession Version	NM_002259.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB464226.1 and AF461812.1. On or before Aug 31, 2013 this sequence version replaced XM_005253359.1, NM_002259.3. Transcript Variant: This variant (1) encodes the longer isoform (NKG2-A). Variants 1 and 3 encode the same isoform (NKG2-A). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF461812.1, X54867.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTGTAAG CATAAGCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002250.1
CDS	215..916
Translation	MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL

Target ORF information:

RefSeq Version	NM_002259.4
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002259.4

ORF Insert Sequence:

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTGTAAG CATAAGCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLRC1 ( NM_001304448.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291377.1 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 5, mRNA.

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CloneID	OHu58640
Clone ID Related Accession (Same CDS sequence)	NM_001304448.1
Accession Version	NM_001304448.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	NKG2-A/NKG2-B type II integral membrane protein isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068775.52 and AK310992.1. On Jan 27, 2015 this sequence version replaced XM_005253360.1. Transcript Variant: This variant (5) has alternate 5' and 3' terminal sequences, compared to variant 1. The resulting isoform (C) is C-terminal truncated, compared to isoform NKG2-A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK310992.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291377.1
CDS	458..1144
Translation	MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYH

Target ORF information:

RefSeq Version	NM_001304448.1
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304448.1

ORF Insert Sequence:

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAGCTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLRC1 ( NM_002259.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002250.2 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 1, mRNA.

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CloneID	OHu108644
Clone ID Related Accession (Same CDS sequence)	NM_002259.5
Accession Version	NM_002259.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068775.52. On Jun 2, 2019 this sequence version replaced NM_002259.4. Transcript Variant: This variant (1) encodes the longer isoform (NKG2-A). Variants 1 and 3 encode the same isoform (NKG2-A). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF461812.1, X54867.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAACTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTGTAAG CATAAGCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002250.2
CDS	212..913
Translation	MDNQGVIYSDLNLPPNPKRQQRKPKGNKNSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL

Target ORF information:

RefSeq Version	NM_002259.5
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002259.5

ORF Insert Sequence:

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAACTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTGTAAG CATAAGCTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLRC1 ( NM_007328.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_015567.2 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu108649
Clone ID Related Accession (Same CDS sequence)	NM_007328.4
Accession Version	NM_007328.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	NKG2-A/NKG2-B type II integral membrane protein isoform NKG2-B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068775.52. On Jun 2, 2019 this sequence version replaced NM_007328.3. Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. The resulting isoform (NKG2-B) is shorter compared to isoform NKG2-A. Variants 2 and 4 encode the same isoform (NKG-2B). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X54868.1, ERR279826.2936.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAACTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCACGTCA TTGTGGCCAT 
TGTCCTGAGG AGTGGATTAC ATATTCCAAC AGTTGTTACT ACATTGGTAA GGAAAGAAGA 
ACTTGGGAAG AGAGTTTGCT GGCCTGTACT TCGAAGAACT CCAGTCTGCT TTCTATAGAT 
AATGAAGAAG AAATGAAATT TCTGTCCATC ATTTCACCAT CCTCATGGAT TGGTGTGTTT 
CGTAACAGCA GTCATCATCC ATGGGTGACA ATGAATGGTT TGGCTTTCAA ACATGAGATA 
AAAGACTCAG ATAATGCTGA ACTTAACTGT GCAGTGCTAC AAGTAAATCG ACTTAAATCA 
GCCCAGTGTG GATCTTCAAT AATATATCAT TGTAAGCATA AGCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_015567.2
CDS	212..859
Translation	MDNQGVIYSDLNLPPNPKRQQRKPKGNKNSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSRHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL

Target ORF information:

RefSeq Version	NM_007328.4
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007328.4

ORF Insert Sequence:

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAACTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCACGTCA TTGTGGCCAT 
TGTCCTGAGG AGTGGATTAC ATATTCCAAC AGTTGTTACT ACATTGGTAA GGAAAGAAGA 
ACTTGGGAAG AGAGTTTGCT GGCCTGTACT TCGAAGAACT CCAGTCTGCT TTCTATAGAT 
AATGAAGAAG AAATGAAATT TCTGTCCATC ATTTCACCAT CCTCATGGAT TGGTGTGTTT 
CGTAACAGCA GTCATCATCC ATGGGTGACA ATGAATGGTT TGGCTTTCAA ACATGAGATA 
AAAGACTCAG ATAATGCTGA ACTTAACTGT GCAGTGCTAC AAGTAAATCG ACTTAAATCA 
GCCCAGTGTG GATCTTCAAT AATATATCAT TGTAAGCATA AGCTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLRC1 ( XM_024448973.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304741.1 Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu103723
Clone ID Related Accession (Same CDS sequence)	XM_024448973.1
Accession Version	XM_024448973.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NKG2-A/NKG2-B type II integral membrane protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAACTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304741.1
CDS	506..1192
Translation	MDNQGVIYSDLNLPPNPKRQQRKPKGNKNSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYH

Target ORF information:

RefSeq Version	XM_024448973.1
Organism	Homo sapiens(human)
Definition	Homo sapiens killer cell lectin like receptor C1 (KLRC1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448973.1

ORF Insert Sequence:

ATGGATAACC AAGGAGTAAT CTACTCAGAC CTGAATCTGC CCCCAAACCC AAAGAGGCAG 
CAACGAAAAC CTAAAGGCAA TAAAAACTCC ATTTTAGCAA CTGAACAGGA AATAACCTAT 
GCGGAATTAA ACCTTCAAAA AGCTTCTCAG GATTTTCAAG GGAATGACAA AACCTATCAC 
TGCAAAGATT TACCATCAGC TCCAGAGAAG CTCATTGTTG GGATCCTGGG AATTATCTGT 
CTTATCTTAA TGGCCTCTGT GGTAACGATA GTTGTTATTC CCTCTACATT AATACAGAGG 
CACAACAATT CTTCCCTGAA TACAAGAACT CAGAAAGCAC GTCATTGTGG CCATTGTCCT 
GAGGAGTGGA TTACATATTC CAACAGTTGT TACTACATTG GTAAGGAAAG AAGAACTTGG 
GAAGAGAGTT TGCTGGCCTG TACTTCGAAG AACTCCAGTC TGCTTTCTAT AGATAATGAA 
GAAGAAATGA AATTTCTGTC CATCATTTCA CCATCCTCAT GGATTGGTGT GTTTCGTAAC 
AGCAGTCATC ATCCATGGGT GACAATGAAT GGTTTGGCTT TCAAACATGA GATAAAAGAC 
TCAGATAATG CTGAACTTAA CTGTGCAGTG CTACAAGTAA ATCGACTTAA ATCAGCCCAG 
TGTGGATCTT CAATAATATA TCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Natural Killer Group 2A Expressed on Both Peripheral CD3
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research36(12)689-697(2016 Dec)
Yi RT,Niu YH,Liu HL,Zhang TY,Yang YC,Zhang Y,Yin DL,Chen TY,Zhao YR

The Activating NKG2C Receptor Is Significantly Reduced in NK Cells after Allogeneic Stem Cell Transplantation in Patients with Severe Graft-versus-Host Disease.
International journal of molecular sciences17(11)(2016 Oct)
Kordelas L,Steckel NK,Horn PA,Beelen DW,Rebmann V

Up-regulation of NKG2A inhibitory receptor on circulating NK cells contributes to transfusion-induced immunodepression in patients with ?-thalassemia major.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban36(4)509-13(2016 Aug)
Zou Y,Song ZX,Lu Y,Liang XL,Yuan Q,Liao SH,Bao JJ

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KLRC1 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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