NHLRC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NHLRC1
Entrez Gene ID	378884
Full Name	NHL repeat containing E3 ubiquitin protein ligase 1
Synonyms	EPM2A,EPM2B,MALIN,bA204B7.2
General protein information	Preferred Names NHL repeat containing E3 ubiquitin protein ligase 1 Names E3 ubiquitin-protein ligase NHLRC1 NHL repeat containing 1 NHL repeat-containing protein 1 RING-type E3 ubiquitin transferase NHLRC1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p22.3
Summary	The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).[provided by RefSeq, Mar 2010].
Disorder MIM:	608072
Disorder Html:	Epilepsy, progressive myoclonic 2B (Lafora), 254780 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_198586.2	NP_940988.2	E3 ubiquitin-protein ligase NHLRC1
NM_198586.3	NP_940988.2	E3 ubiquitin-protein ligase NHLRC1

Pathways from BioSystems

Homologies

Homo sapiens (human)	NHLRC1	NP_940988.2
Bos taurus (cattle)	NHLRC1	XP_002697596.1
Gallus gallus (chicken)	NHLRC1	XP_426034.2
Xenopus tropicalis (tropical clawed frog)	nhlrc1	XP_002932735.1
Pan troglodytes (chimpanzee)	NHLRC1	XP_001170828.1
Canis lupus familiaris (dog)	NHLRC1	NP_001006650.1
Mus musculus (house mouse)	Nhlrc1	NP_780549.1
	NHLRC1	XP_001097330.1
Rattus norvegicus (Norway rat)	Nhlrc1	NP_954706.1

Gene Ontology
Bibliography

Related articles in PubMed

Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease.
Mittal S, Upadhyay M, Singh PK, Parihar R, Ganesh S
Journal of biosciences40(5)863-71(2015 Dec)

The laforin/malin E3-ubiquitin ligase complex ubiquitinates pyruvate kinase M1/M2.
Viana R, Lujan P, Sanz P
BMC biochemistry1624(2015 Oct)

Lafora disease proteins laforin and malin negatively regulate the HIPK2-p53 cell death pathway.
Upadhyay M, Gupta S, Bhadauriya P, Ganesh S
Biochemical and biophysical research communications464(1)106-11(2015 Aug)

Mild Lafora disease: clinical, neurophysiologic, and genetic findings.
Ferlazzo E, Canafoglia L, Michelucci R, Gambardella A, Gennaro E, Pasini E, Riguzzi P, Plasmati R, Volpi L, Labate A, Gasparini S, Villani F, Casazza M, Viri M, Zara F, Minassian BA, Turnbull J, Serratosa JM, Guerrero-L?pez R, Franceschetti S, Aguglia U
Epilepsia55(12)e129-33(2014 Dec)

Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylase.
Liu Y, Zeng L, Ma K, Baba O, Zheng P, Liu Y, Wang Y
Molecular neurobiology49(2)645-57(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Malin promotes its own degradation via auto-ubiquitination.Malin preferentially degrades the phosphatase-inactive laforin monomer.
Title: Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease.

laforin/malin complex is able to interact with and ubiquitinate both PKM1 and PKM2
Title: The laforin/malin E3-ubiquitin ligase complex ubiquitinates pyruvate kinase M1/M2.

Lafora disease proteins laforin and malin negatively regulate the HIPK2-p53 cell death pathway.
Title: Lafora disease proteins laforin and malin negatively regulate the HIPK2-p53 cell death pathway.

This study demonistrated that NHLRC1 mutations were detected in some case of Mild Lafora disease patients.
Title: Mild Lafora disease: clinical, neurophysiologic, and genetic findings.

Without functional laforin-malin complex assembled on polyglucosan bodies, polyglucosan is not degraded.
Title: Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylase.

The following NHLRC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NHLRC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18073	NM_198586.3 Latest version!	Homo sapiens NHL repeat containing E3 ubiquitin protein ligase 1 (NHLRC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu18073	NM_198586.2	Homo sapiens NHL repeat containing E3 ubiquitin protein ligase 1 (NHLRC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NHLRC1 ( NM_198586.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_940988.2 Homo sapiens NHL repeat containing E3 ubiquitin protein ligase 1 (NHLRC1), mRNA.

Price & Availability↑

CloneID	OHu18073
Clone ID Related Accession (Same CDS sequence)	NM_198586.2 , NM_198586.3
Accession Version	NM_198586.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase NHLRC1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BK001510.1. This sequence is a reference standard in the RefSeqGene project. On Dec 20, 2003 this sequence version replaced NM_198586.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BK001510.1, SRR1803615.16296.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCG AAGCCTCGGA GAGCGGGCCA GCGCTGCATG AGCTCATGCG CGAGGCGGAG 
ATCAGCCTGC TCGAGTGCAA GGTGTGCTTT GAGAAGTTTG GCCACCGGCA GCAGCGGCGC 
CCGCGCAACC TGTCCTGCGG CCACGTGGTC TGCCTGGCCT GCGTGGCCGC CCTGGCGCAC 
CCGCGCACTC TGGCCCTCGA GTGCCCATTC TGCAGGCGAG CTTGCCGGGG CTGCGACACC 
AGCGACTGCC TGCCGGTGCT GCACCTCATA GAGCTCCTGG GCTCAGCGCT TCGCCAGTCC 
CCGGCCGCCC ATCGCGCCGC CCCCAGCGCC CCCGGAGCCC TCACCTGCCA CCACACCTTC 
GGCGGCTGGG GGACCCTGGT CAACCCCACC GGACTGGCGC TTTGTCCCAA GACGGGGCGT 
GTCGTGGTGG TGCACGACGG CAGGAGGCGT GTCAAGATTT TTGACTCAGG GGGAGGATGC 
GCGCATCAGT TTGGAGAGAA GGGGGACGCT GCCCAAGACA TTAGGTACCC TGTGGATGTC 
ACCATCACCA ACGACTGCCA TGTGGTTGTC ACTGACGCCG GCGATCGCTC CATCAAAGTG 
TTTGATTTTT TTGGCCAGAT CAAGCTTGTC ATTGGAGGCC AATTCTCCTT ACCTTGGGGT 
GTGGAGACCA CCCCTCAGAA TGGGATTGTG GTAACTGATG CGGAGGCAGG GTCCCTGCAC 
CTCCTGGACG TCGACTTCGC GGAAGGGGTC CTTCGGAGAA CTGAAAGGTT GCAAGCTCAT 
CTGTGCAATC CCCGAGGGGT GGCAGTGTCT TGGCTCACCG GGGCCATTGC GGTCCTGGAG 
CACCCCCTGG CCCTGGGGAC TGGGGTTTGC AGCACCAGGG TGAAAGTGTT TAGCTCAAGT 
ATGCAGCTTG TCGGCCAAGT GGATACCTTT GGGCTGAGCC TCTACTTTCC CTCCAAAATA 
ACTGCCTCCG CTGTGACCTT TGATCACCAG GGAAATGTGA TTGTTGCAGA TACATCTGGT 
CCAGCTATCC TTTGCTTAGG AAAACCTGAG GAGTTTCCAG TACCGAAGCC CATGGTCACT 
CATGGTCTTT CGCATCCTGT GGCTCTTACC TTCACCAAGG AGAATTCTCT TCTTGTGCTG 
GACACAGCAT CTCATTCTAT AAAAGTCTAT AAAGTTGACT GGGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940988.2
CDS	15..1202
Translation	MAAEASESGPALHELMREAEISLLECKVCFEKFGHRQQRRPRNLSCGHVVCLACVAALAHPRTLALECPFCRRACRGCDTSDCLPVLHLIELLGSALRQSPAAHRAAPSAPGALTCHHTFGGWGTLVNPTGLALCPKTGRVVVVHDGRRRVKIFDSGGGCAHQFGEKGDAAQDIRYPVDVTITNDCHVVVTDAGDRSIKVFDFFGQIKLVIGGQFSLPWGVETTPQNGIVVTDAEAGSLHLLDVDFAEGVLRRTERLQAHLCNPRGVAVSWLTGAIAVLEHPLALGTGVCSTRVKVFSSSMQLVGQVDTFGLSLYFPSKITASAVTFDHQGNVIVADTSGPAILCLGKPEEFPVPKPMVTHGLSHPVALTFTKENSLLVLDTASHSIKVYKVDWG

Target ORF information:

RefSeq Version	NM_198586.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NHL repeat containing E3 ubiquitin protein ligase 1 (NHLRC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198586.2

ORF Insert Sequence:

ATGGCGGCCG AAGCCTCGGA GAGCGGGCCA GCGCTGCATG AGCTCATGCG CGAGGCGGAG 
ATCAGCCTGC TCGAGTGCAA GGTGTGCTTT GAGAAGTTTG GCCACCGGCA GCAGCGGCGC 
CCGCGCAACC TGTCCTGCGG CCACGTGGTC TGCCTGGCCT GCGTGGCCGC CCTGGCGCAC 
CCGCGCACTC TGGCCCTCGA GTGCCCATTC TGCAGGCGAG CTTGCCGGGG CTGCGACACC 
AGCGACTGCC TGCCGGTGCT GCACCTCATA GAGCTCCTGG GCTCAGCGCT TCGCCAGTCC 
CCGGCCGCCC ATCGCGCCGC CCCCAGCGCC CCCGGAGCCC TCACCTGCCA CCACACCTTC 
GGCGGCTGGG GGACCCTGGT CAACCCCACC GGACTGGCGC TTTGTCCCAA GACGGGGCGT 
GTCGTGGTGG TGCACGACGG CAGGAGGCGT GTCAAGATTT TTGACTCAGG GGGAGGATGC 
GCGCATCAGT TTGGAGAGAA GGGGGACGCT GCCCAAGACA TTAGGTACCC TGTGGATGTC 
ACCATCACCA ACGACTGCCA TGTGGTTGTC ACTGACGCCG GCGATCGCTC CATCAAAGTG 
TTTGATTTTT TTGGCCAGAT CAAGCTTGTC ATTGGAGGCC AATTCTCCTT ACCTTGGGGT 
GTGGAGACCA CCCCTCAGAA TGGGATTGTG GTAACTGATG CGGAGGCAGG GTCCCTGCAC 
CTCCTGGACG TCGACTTCGC GGAAGGGGTC CTTCGGAGAA CTGAAAGGTT GCAAGCTCAT 
CTGTGCAATC CCCGAGGGGT GGCAGTGTCT TGGCTCACCG GGGCCATTGC GGTCCTGGAG 
CACCCCCTGG CCCTGGGGAC TGGGGTTTGC AGCACCAGGG TGAAAGTGTT TAGCTCAAGT 
ATGCAGCTTG TCGGCCAAGT GGATACCTTT GGGCTGAGCC TCTACTTTCC CTCCAAAATA 
ACTGCCTCCG CTGTGACCTT TGATCACCAG GGAAATGTGA TTGTTGCAGA TACATCTGGT 
CCAGCTATCC TTTGCTTAGG AAAACCTGAG GAGTTTCCAG TACCGAAGCC CATGGTCACT 
CATGGTCTTT CGCATCCTGT GGCTCTTACC TTCACCAAGG AGAATTCTCT TCTTGTGCTG 
GACACAGCAT CTCATTCTAT AAAAGTCTAT AAAGTTGACT GGGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NHLRC1 ( NM_198586.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_940988.2 Homo sapiens NHL repeat containing E3 ubiquitin protein ligase 1 (NHLRC1), mRNA.

Price & Availability↑

CloneID	OHu18073
Clone ID Related Accession (Same CDS sequence)	NM_198586.2 , NM_198586.3
Accession Version	NM_198586.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	E3 ubiquitin-protein ligase NHLRC1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL589723.7 and BK001510.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_198586.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BK001510.1, SRR1803615.16296.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000340650.6/ ENSP00000345464.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCG AAGCCTCGGA GAGCGGGCCA GCGCTGCATG AGCTCATGCG CGAGGCGGAG 
ATCAGCCTGC TCGAGTGCAA GGTGTGCTTT GAGAAGTTTG GCCACCGGCA GCAGCGGCGC 
CCGCGCAACC TGTCCTGCGG CCACGTGGTC TGCCTGGCCT GCGTGGCCGC CCTGGCGCAC 
CCGCGCACTC TGGCCCTCGA GTGCCCATTC TGCAGGCGAG CTTGCCGGGG CTGCGACACC 
AGCGACTGCC TGCCGGTGCT GCACCTCATA GAGCTCCTGG GCTCAGCGCT TCGCCAGTCC 
CCGGCCGCCC ATCGCGCCGC CCCCAGCGCC CCCGGAGCCC TCACCTGCCA CCACACCTTC 
GGCGGCTGGG GGACCCTGGT CAACCCCACC GGACTGGCGC TTTGTCCCAA GACGGGGCGT 
GTCGTGGTGG TGCACGACGG CAGGAGGCGT GTCAAGATTT TTGACTCAGG GGGAGGATGC 
GCGCATCAGT TTGGAGAGAA GGGGGACGCT GCCCAAGACA TTAGGTACCC TGTGGATGTC 
ACCATCACCA ACGACTGCCA TGTGGTTGTC ACTGACGCCG GCGATCGCTC CATCAAAGTG 
TTTGATTTTT TTGGCCAGAT CAAGCTTGTC ATTGGAGGCC AATTCTCCTT ACCTTGGGGT 
GTGGAGACCA CCCCTCAGAA TGGGATTGTG GTAACTGATG CGGAGGCAGG GTCCCTGCAC 
CTCCTGGACG TCGACTTCGC GGAAGGGGTC CTTCGGAGAA CTGAAAGGTT GCAAGCTCAT 
CTGTGCAATC CCCGAGGGGT GGCAGTGTCT TGGCTCACCG GGGCCATTGC GGTCCTGGAG 
CACCCCCTGG CCCTGGGGAC TGGGGTTTGC AGCACCAGGG TGAAAGTGTT TAGCTCAAGT 
ATGCAGCTTG TCGGCCAAGT GGATACCTTT GGGCTGAGCC TCTACTTTCC CTCCAAAATA 
ACTGCCTCCG CTGTGACCTT TGATCACCAG GGAAATGTGA TTGTTGCAGA TACATCTGGT 
CCAGCTATCC TTTGCTTAGG AAAACCTGAG GAGTTTCCAG TACCGAAGCC CATGGTCACT 
CATGGTCTTT CGCATCCTGT GGCTCTTACC TTCACCAAGG AGAATTCTCT TCTTGTGCTG 
GACACAGCAT CTCATTCTAT AAAAGTCTAT AAAGTTGACT GGGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940988.2
CDS	72..1259
Translation	MAAEASESGPALHELMREAEISLLECKVCFEKFGHRQQRRPRNLSCGHVVCLACVAALAHPRTLALECPFCRRACRGCDTSDCLPVLHLIELLGSALRQSPAAHRAAPSAPGALTCHHTFGGWGTLVNPTGLALCPKTGRVVVVHDGRRRVKIFDSGGGCAHQFGEKGDAAQDIRYPVDVTITNDCHVVVTDAGDRSIKVFDFFGQIKLVIGGQFSLPWGVETTPQNGIVVTDAEAGSLHLLDVDFAEGVLRRTERLQAHLCNPRGVAVSWLTGAIAVLEHPLALGTGVCSTRVKVFSSSMQLVGQVDTFGLSLYFPSKITASAVTFDHQGNVIVADTSGPAILCLGKPEEFPVPKPMVTHGLSHPVALTFTKENSLLVLDTASHSIKVYKVDWG

Target ORF information:

RefSeq Version	NM_198586.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NHL repeat containing E3 ubiquitin protein ligase 1 (NHLRC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198586.3

ORF Insert Sequence:

ATGGCGGCCG AAGCCTCGGA GAGCGGGCCA GCGCTGCATG AGCTCATGCG CGAGGCGGAG 
ATCAGCCTGC TCGAGTGCAA GGTGTGCTTT GAGAAGTTTG GCCACCGGCA GCAGCGGCGC 
CCGCGCAACC TGTCCTGCGG CCACGTGGTC TGCCTGGCCT GCGTGGCCGC CCTGGCGCAC 
CCGCGCACTC TGGCCCTCGA GTGCCCATTC TGCAGGCGAG CTTGCCGGGG CTGCGACACC 
AGCGACTGCC TGCCGGTGCT GCACCTCATA GAGCTCCTGG GCTCAGCGCT TCGCCAGTCC 
CCGGCCGCCC ATCGCGCCGC CCCCAGCGCC CCCGGAGCCC TCACCTGCCA CCACACCTTC 
GGCGGCTGGG GGACCCTGGT CAACCCCACC GGACTGGCGC TTTGTCCCAA GACGGGGCGT 
GTCGTGGTGG TGCACGACGG CAGGAGGCGT GTCAAGATTT TTGACTCAGG GGGAGGATGC 
GCGCATCAGT TTGGAGAGAA GGGGGACGCT GCCCAAGACA TTAGGTACCC TGTGGATGTC 
ACCATCACCA ACGACTGCCA TGTGGTTGTC ACTGACGCCG GCGATCGCTC CATCAAAGTG 
TTTGATTTTT TTGGCCAGAT CAAGCTTGTC ATTGGAGGCC AATTCTCCTT ACCTTGGGGT 
GTGGAGACCA CCCCTCAGAA TGGGATTGTG GTAACTGATG CGGAGGCAGG GTCCCTGCAC 
CTCCTGGACG TCGACTTCGC GGAAGGGGTC CTTCGGAGAA CTGAAAGGTT GCAAGCTCAT 
CTGTGCAATC CCCGAGGGGT GGCAGTGTCT TGGCTCACCG GGGCCATTGC GGTCCTGGAG 
CACCCCCTGG CCCTGGGGAC TGGGGTTTGC AGCACCAGGG TGAAAGTGTT TAGCTCAAGT 
ATGCAGCTTG TCGGCCAAGT GGATACCTTT GGGCTGAGCC TCTACTTTCC CTCCAAAATA 
ACTGCCTCCG CTGTGACCTT TGATCACCAG GGAAATGTGA TTGTTGCAGA TACATCTGGT 
CCAGCTATCC TTTGCTTAGG AAAACCTGAG GAGTTTCCAG TACCGAAGCC CATGGTCACT 
CATGGTCTTT CGCATCCTGT GGCTCTTACC TTCACCAAGG AGAATTCTCT TCTTGTGCTG 
GACACAGCAT CTCATTCTAT AAAAGTCTAT AAAGTTGACT GGGGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease.
Journal of biosciences40(5)863-71(2015 Dec)
Mittal S,Upadhyay M,Singh PK,Parihar R,Ganesh S

The laforin/malin E3-ubiquitin ligase complex ubiquitinates pyruvate kinase M1/M2.
BMC biochemistry1624(2015 Oct)
Viana R,Lujan P,Sanz P

Lafora disease proteins laforin and malin negatively regulate the HIPK2-p53 cell death pathway.
Biochemical and biophysical research communications464(1)106-11(2015 Aug)
Upadhyay M,Gupta S,Bhadauriya P,Ganesh S

Mild Lafora disease: clinical, neurophysiologic, and genetic findings.
Epilepsia55(12)e129-33(2014 Dec)
Ferlazzo E,Canafoglia L,Michelucci R,Gambardella A,Gennaro E,Pasini E,Riguzzi P,Plasmati R,Volpi L,Labate A,Gasparini S,Villani F,Casazza M,Viri M,Zara F,Minassian BA,Turnbull J,Serratosa JM,Guerrero-L?pez R,Franceschetti S,Aguglia U

Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylase.
Molecular neurobiology49(2)645-57(2014 Apr)
Liu Y,Zeng L,Ma K,Baba O,Zheng P,Liu Y,Wang Y

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NHLRC1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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