ENHO cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ENHO
Entrez Gene ID	375704
Full Name	energy homeostasis associated
Synonyms	C9orf165,UNQ470
General protein information	Preferred Names energy homeostasis associated Names adropin GAAI470 energy homeostasis-associated protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p13.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_198573.2	NP_940975.2	adropin precursor
NM_198573.3	NP_940975.2	adropin precursor

Pathways from BioSystems

Homologies

	ENHO	XP_001097511.1
Rattus norvegicus (Norway rat)	LOC100912292	NP_001269265.1
Pan troglodytes (chimpanzee)	ENHO	XP_003312104.1
Canis lupus familiaris (dog)	ENHO	XP_003431614.1
Homo sapiens (human)	ENHO	NP_940975.2
Mus musculus (house mouse)	Enho	NP_081423.1

Gene Ontology
Bibliography

Related articles in PubMed

Adropin: An endocrine link between the biological clock and cholesterol homeostasis.
Ghoshal S, Stevens JR, Billon C, Girardet C, Sitaula S, Leon AS, Rao DC, Skinner JS, Rankinen T, Bouchard C, Nu?ez MV, Stanhope KL, Howatt DA, Daugherty A, Zhang J, Schuelke M, Weiss EP, Coffey AR, Bennett BJ, Sethupathy P, Burris TP, Havel PJ, Butler AA
Molecular metabolism(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that serum adropin (ENHO) levels in normal, overweight, and obese adults negatively correlate with vascular stiffness (using common carotid artery) and adiposity (using abdominal visceral fat), and positively correlate with plasma nitric oxide levels (using nitrite/nitrate) and cardiorespiratory fitness; aerobic exercise training up-regulates serum adropin.
Title: Association between aerobic exercise training effects of serum adropin level, arterial stiffness, and adiposity in obese elderly adults.

In HD patients, lower plasma adropin concentration is associated with dyslipidemia. Major homozygosity of RXRA seems to have an opposite effect on plasma adropin compared with that of ENHO rs2281997
Title: Involvement of adropin and adropin-associated genes in metabolic abnormalities of hemodialysis patients.

Enho mutations plays a critical role in activating endothelial cells during neutrophil recruitment and neutrophil-endothelium cell interactions under IL-1 and TNF-alpha-induced vascular inflammation and increases susceptibility to MPOANCA associated lung injury.
Title: Enho Mutations Causing Low Adropin: A Possible Pathomechanism of MPO-ANCA Associated Lung Injury.

There were no significant differences among the groups of systemic sclerosis (SSc) and controls in terms of ENHO gene expressions. There was no significant difference between the limited and diffuse cutaneous subtypes of SSc in terms of serum adropin level and ENHO gene expression. Moreover, serum adropin level and ENHO gene expression were not associated with the disease activity and severity indexes.
Title: Serum adropin level and ENHO gene expression in systemic sclerosis.

Serum adropin concentrations are negatively associated with renal function.
Title: Association of Serum Adropin Concentrations with Diabetic Nephropathy.

The following ENHO gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ENHO cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01010	NM_198573.3 Latest version!	Homo sapiens energy homeostasis associated (ENHO), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu01010	NM_198573.2	Homo sapiens energy homeostasis associated (ENHO), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ENHO ( NM_198573.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_940975.2 Homo sapiens energy homeostasis associated (ENHO), mRNA.

Price & Availability↑

CloneID	OHu01010
Clone ID Related Accession (Same CDS sequence)	NM_198573.2 , NM_198573.3
Accession Version	NM_198573.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	adropin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI554721.1, BQ932712.1, AY358658.1 and BX111579.1. On Jan 26, 2005 this sequence version replaced NM_198573.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279849.676.1, ERR279872.1272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCAG CCATCTCCCA GGGGGCCCTC ATCGCCATCG TCTGCAACGG TCTCGTGGGC 
TTCTTGCTGC TGCTGCTCTG GGTCATCCTC TGCTGGGCCT GCCATTCTCG CTCTGCCGAC 
GTTGACTCTC TCTCTGAATC CAGTCCCAAC TCCAGCCCTG GCCCCTGTCC TGAGAAGGCC 
CCACCACCCC AGAAGCCCAG CCATGAAGGC AGCTACCTGC TGCAGCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940975.2
CDS	425..655
Translation	MGAAISQGALIAIVCNGLVGFLLLLLWVILCWACHSRSADVDSLSESSPNSSPGPCPEKAPPPQKPSHEGSYLLQP

Target ORF information:

RefSeq Version	NM_198573.2
Organism	Homo sapiens(human)
Definition	Homo sapiens energy homeostasis associated (ENHO), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198573.2

ORF Insert Sequence:

ATGGGGGCAG CCATCTCCCA GGGGGCCCTC ATCGCCATCG TCTGCAACGG TCTCGTGGGC 
TTCTTGCTGC TGCTGCTCTG GGTCATCCTC TGCTGGGCCT GCCATTCTCG CTCTGCCGAC 
GTTGACTCTC TCTCTGAATC CAGTCCCAAC TCCAGCCCTG GCCCCTGTCC TGAGAAGGCC 
CCACCACCCC AGAAGCCCAG CCATGAAGGC AGCTACCTGC TGCAGCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ENHO ( NM_198573.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_940975.2 Homo sapiens energy homeostasis associated (ENHO), mRNA.

Price & Availability↑

CloneID	OHu01010
Clone ID Related Accession (Same CDS sequence)	NM_198573.2 , NM_198573.3
Accession Version	NM_198573.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	adropin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL160270.19. On Nov 23, 2018 this sequence version replaced NM_198573.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279849.676.1, ERR279872.1272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000399775.3/ ENSP00000382675.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGGCAG CCATCTCCCA GGGGGCCCTC ATCGCCATCG TCTGCAACGG TCTCGTGGGC 
TTCTTGCTGC TGCTGCTCTG GGTCATCCTC TGCTGGGCCT GCCATTCTCG CTCTGCCGAC 
GTTGACTCTC TCTCTGAATC CAGTCCCAAC TCCAGCCCTG GCCCCTGTCC TGAGAAGGCC 
CCACCACCCC AGAAGCCCAG CCATGAAGGC AGCTACCTGC TGCAGCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940975.2
CDS	376..606
Translation	MGAAISQGALIAIVCNGLVGFLLLLLWVILCWACHSRSADVDSLSESSPNSSPGPCPEKAPPPQKPSHEGSYLLQP

Target ORF information:

RefSeq Version	NM_198573.3
Organism	Homo sapiens(human)
Definition	Homo sapiens energy homeostasis associated (ENHO), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198573.3

ORF Insert Sequence:

ATGGGGGCAG CCATCTCCCA GGGGGCCCTC ATCGCCATCG TCTGCAACGG TCTCGTGGGC 
TTCTTGCTGC TGCTGCTCTG GGTCATCCTC TGCTGGGCCT GCCATTCTCG CTCTGCCGAC 
GTTGACTCTC TCTCTGAATC CAGTCCCAAC TCCAGCCCTG GCCCCTGTCC TGAGAAGGCC 
CCACCACCCC AGAAGCCCAG CCATGAAGGC AGCTACCTGC TGCAGCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Adropin: An endocrine link between the biological clock and cholesterol homeostasis.
Molecular metabolism(2017 Dec)
Ghoshal S,Stevens JR,Billon C,Girardet C,Sitaula S,Leon AS,Rao DC,Skinner JS,Rankinen T,Bouchard C,Nu?ez MV,Stanhope KL,Howatt DA,Daugherty A,Zhang J,Schuelke M,Weiss EP,Coffey AR,Bennett BJ,Sethupathy P,Burris TP,Havel PJ,Butler AA

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ENHO cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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