PTCHD3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PTCHD3
Entrez Gene ID	374308
Full Name	patched domain containing 3
Synonyms	PTR
General protein information	Preferred Names patched domain containing 3 Names patched domain-containing protein 3 patched-related protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10p12.1
Disorder MIM:	611791

mRNA and Protein(s)

mRNA	Protein	Name
NM_001034842.3	NP_001030014.2	patched domain-containing protein 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PTCHD3	XP_005642513.1
Mus musculus (house mouse)	Ptchd3	NP_083325.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010394	XP_311553.4
Homo sapiens (human)	PTCHD3	NP_001030014.2
Pan troglodytes (chimpanzee)	PTCHD3	XP_507715.2
Caenorhabditis elegans (roundworm)	ptr-19	NP_001255085.1
Bos taurus (cattle)	LOC516442	XP_002698222.1
Rattus norvegicus (Norway rat)	Ptchd3	XP_003751038.1
Xenopus tropicalis (tropical clawed frog)	ptchd3	XP_002933185.2
	PTCHD3	XP_001105179.1
Gallus gallus (chicken)	PTCHD3	XP_425978.3
Drosophila melanogaster (fruit fly)	Ptr	NP_001246145.1

Gene Ontology
Bibliography

Related articles in PubMed

Human PTCHD3 nulls: rare copy number and sequence variants suggest a non-essential gene.
Ghahramani Seno MM, Kwan BY, Lee-Ng KK, Moessner R, Lionel AC, Marshall CR, Scherer SW
BMC medical genetics1245(2011 Mar)

Male germ cell-specific expression of a novel Patched-domain containing gene Ptchd3.
Fan J, Akabane H, Zheng X, Zhou X, Zhang L, Liu Q, Zhang YL, Yang J, Zhu GZ
Biochemical and biophysical research communications363(3)757-61(2007 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PTCHD3 nulls: rare copy number and sequence variants suggest a non-essential gene.
Title: Human PTCHD3 nulls: rare copy number and sequence variants suggest a non-essential gene.

Results indicate that Ptchd3 is a novel male germ cell-specific gene and may be involved in the Hh signaling to regulate sperm development and/or sperm function.
Title: Male germ cell-specific expression of a novel Patched-domain containing gene Ptchd3.

The following PTCHD3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PTCHD3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu24369	NM_001034842.3 Latest version!	Homo sapiens patched domain containing 3 (PTCHD3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PTCHD3 ( NM_001034842.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001030014.2 Homo sapiens patched domain containing 3 (PTCHD3), mRNA.

Price & Availability↑

CloneID	OHu24369
Clone ID Related Accession (Same CDS sequence)	NM_001034842.3
Accession Version	NM_001034842.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2304bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	patched domain-containing protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL355493.14, BC107139.2 and DB509520.2. On Jul 10, 2008 this sequence version replaced NM_001034842.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK126025.1, BC107139.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCCGTGGG TGGAGCCCAA GCCCAGGCCG GGGCCGGAGC AGAAGCCCAA GCTCACCAAA 
CCGGACTCTG CCACCGGGCC GCAGTGGTAC CAGGAATCTC AGGAATCGGA GTCGGAAGGC 
AAGCAGCCAC CCCCGGGACC CCTGGCACCC CCGAAATCCC CCGAACCCTC AGGACCCCTG 
GCGTCGGAGC AGGATGCACC CCTGCCAGAG GGGGACGATG CACCCCCCCG GCCGTCGATG 
CTGGACGATG CACCCCGCCT GCCGCTGGAG CTGGACGATG CACCCCTGCC GGAGGAGGAA 
ACCCCCGAAC CCACGGCCAT CTGCAGGCAC CGGCACCGCT GTCACACCGA CTGCCTAGAG 
GGGCTGCTGT CCCGCACCTT CCAGTGGCTG GGGTGGCAGG TGGGCGCGCA CCCCTGGATC 
TTCCTGCTGG CGCCCTTGAT GCTGACAGCC GCGCTGGGCA CCGGCTTCCT GTACCTACCC 
AAGGACGAAG AGGAAGACCT AGAGGAGCAT TACACCCCTG TGGGGAGCCC GGCCAAGGCG 
GAGCGGCGCT TCGTGCAGGG CCATTTCACC ACCAACGACT CCTACCGCTT CTCCGCCTCC 
AGGAGGAGCA CCGAAGCCAA TTTCGTCTCG CTTCTGGTGG TCTCCTACAG CGACTCACTG 
CTGGACCCAG CTACCTTTGC AGAAGTCAGC AAACTGGACG GCGCGGTGCA GGATCTGCGC 
GTGGCGCGGG AAAAGGGAAG CCAGATCCAG TACCAGCAGG TGTGCGCGAG GTACAGGGCG 
CTCTGCGTGC CCCCCAACCC GATCCTGTAC GCCTGGCAGG TGAACAAAAC GCTCAACCTG 
AGCAGCATCT CCTTCCCCGC CTACAACCAC GGCAGGCATC CCCTCTACCT GACCGGCTTC 
TTCGGAGGAT ACATCTTGGG GGGCAGCCTA GGAATGGGCC AGTTACTCCT GCGGGCCAAA 
GCCATGCGGC TGCTGTACTA CCTGAAGACC GAGGACCCTG AGTACGACGT GCAGAGCAAG 
CAGTGGCTCA CCCATTTGCT CGATCAATTT ACCAACATTA AGAACATCTT GGCCTTGAAA 
AAAATTGAGG TAGTCCACTT TACATCGCTT TCCAGACAAC TGGAATTTGA GGCAACTTCT 
GTGACTGTGA TCCCTGTGTT TCACCTGGCA TACATTCTCA TCATTCTGTT TGCAGTCACA 
TCATGCTTTA GGTTTGACTG CATACGAAAC AAAATGTGTG TTGCGGCCTT TGGAGTGATT 
TCTGCTTTCT TGGCAGTGGT GAGCGGCTTT GGCCTGCTGT TGCACATTGG GGTGCCATTT 
GTCATCATAG TTGCCAATTC ACCATTTCTT ATTCTAGGTG TTGGGGTCGA TGACATGTTT 
ATCATGATTT CTGCCTGGCA TAAGACCAAC CTTGCAGATG ACATACGAGA GCGGATGTCC 
AATGTCTATT CAAAAGCGGC AGTGTCTATT ACAATCACCA CCATCACTAA CATCCTGGCC 
TTATATACAG GGATTATGAG CTCTTTTAGG TCTGTACAAT GTTTTTGCAT CTATACAGGA 
ATGACCCTGT TATTTTGCTA TTTTTATAAC ATCACGTGTT TTGGAGCATT TATGGCCTTG 
GATGGTAAAA GAGAAGTAGT CTGCCTATGC TGGTTGAAAA AGGCTGACCC AAAATGGCCC 
TCATTTAAAA AGTTCTGCTG TTTCCCATTT GGTTCTGTCC CAGATGAACA TGGAACTGAT 
ATCCATCCAA TAAGTTTGTT TTTTAGAGAC TATTTTGGCC CCTTTCTCAC AAGGAGTGAG 
TCCAAGTATT TTGTAGTCTT TATATATGTT TTGTACATCA TAAGCAGTAT ATATGGGTGT 
TTCCATGTGC AGGAAGGTTT AGACCTTCGA AATCTGGCAA GTGACGATTC CTACATCACA 
CCATATTTTA ACGTAGAGGA GAATTATTTT TCAGATTATG GTCCCAGGGT TATGGTTATT 
GTTACTAAAA AAGTTGACTA CTGGGATAAA GATGTTAGGC AAAAACTGGA AAACTGTACT 
AAAATTTTTG AAAAAAATGT CTATGTAGAT AAAAATCTTA CAGAGTTTTG GTTAGATGCA 
TATGTGCAAT ATTTAAAAGG TAACAGCCAA GATCCTAATG AGAAGAATAC TTTTATGAAC 
AATATTCCTG ATTTTTTAAG CAATTTTCCA AATTTTCAGC ATGATATTAA TATTTCTTCA 
TCAAATGAAA TCATTTCTTC CCGGGGCTTC ATTCAGACAA CAGATGTTTC TTCCTCAGCC 
AAAAAGAAAA TATTGTTATT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030014.2
CDS	119..2422
Translation	MPWVEPKPRPGPEQKPKLTKPDSATGPQWYQESQESESEGKQPPPGPLAPPKSPEPSGPLASEQDAPLPEGDDAPPRPSMLDDAPRLPLELDDAPLPEEETPEPTAICRHRHRCHTDCLEGLLSRTFQWLGWQVGAHPWIFLLAPLMLTAALGTGFLYLPKDEEEDLEEHYTPVGSPAKAERRFVQGHFTTNDSYRFSASRRSTEANFVSLLVVSYSDSLLDPATFAEVSKLDGAVQDLRVAREKGSQIQYQQVCARYRALCVPPNPILYAWQVNKTLNLSSISFPAYNHGRHPLYLTGFFGGYILGGSLGMGQLLLRAKAMRLLYYLKTEDPEYDVQSKQWLTHLLDQFTNIKNILALKKIEVVHFTSLSRQLEFEATSVTVIPVFHLAYILIILFAVTSCFRFDCIRNKMCVAAFGVISAFLAVVSGFGLLLHIGVPFVIIVANSPFLILGVGVDDMFIMISAWHKTNLADDIRERMSNVYSKAAVSITITTITNILALYTGIMSSFRSVQCFCIYTGMTLLFCYFYNITCFGAFMALDGKREVVCLCWLKKADPKWPSFKKFCCFPFGSVPDEHGTDIHPISLFFRDYFGPFLTRSESKYFVVFIYVLYIISSIYGCFHVQEGLDLRNLASDDSYITPYFNVEENYFSDYGPRVMVIVTKKVDYWDKDVRQKLENCTKIFEKNVYVDKNLTEFWLDAYVQYLKGNSQDPNEKNTFMNNIPDFLSNFPNFQHDINISSSNEIISSRGFIQTTDVSSSAKKKILLF

Target ORF information:

RefSeq Version	NM_001034842.3
Organism	Homo sapiens(human)
Definition	Homo sapiens patched domain containing 3 (PTCHD3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001034842.3

ORF Insert Sequence:

ATGCCGTGGG TGGAGCCCAA GCCCAGGCCG GGGCCGGAGC AGAAGCCCAA GCTCACCAAA 
CCGGACTCTG CCACCGGGCC GCAGTGGTAC CAGGAATCTC AGGAATCGGA GTCGGAAGGC 
AAGCAGCCAC CCCCGGGACC CCTGGCACCC CCGAAATCCC CCGAACCCTC AGGACCCCTG 
GCGTCGGAGC AGGATGCACC CCTGCCAGAG GGGGACGATG CACCCCCCCG GCCGTCGATG 
CTGGACGATG CACCCCGCCT GCCGCTGGAG CTGGACGATG CACCCCTGCC GGAGGAGGAA 
ACCCCCGAAC CCACGGCCAT CTGCAGGCAC CGGCACCGCT GTCACACCGA CTGCCTAGAG 
GGGCTGCTGT CCCGCACCTT CCAGTGGCTG GGGTGGCAGG TGGGCGCGCA CCCCTGGATC 
TTCCTGCTGG CGCCCTTGAT GCTGACAGCC GCGCTGGGCA CCGGCTTCCT GTACCTACCC 
AAGGACGAAG AGGAAGACCT AGAGGAGCAT TACACCCCTG TGGGGAGCCC GGCCAAGGCG 
GAGCGGCGCT TCGTGCAGGG CCATTTCACC ACCAACGACT CCTACCGCTT CTCCGCCTCC 
AGGAGGAGCA CCGAAGCCAA TTTCGTCTCG CTTCTGGTGG TCTCCTACAG CGACTCACTG 
CTGGACCCAG CTACCTTTGC AGAAGTCAGC AAACTGGACG GCGCGGTGCA GGATCTGCGC 
GTGGCGCGGG AAAAGGGAAG CCAGATCCAG TACCAGCAGG TGTGCGCGAG GTACAGGGCG 
CTCTGCGTGC CCCCCAACCC GATCCTGTAC GCCTGGCAGG TGAACAAAAC GCTCAACCTG 
AGCAGCATCT CCTTCCCCGC CTACAACCAC GGCAGGCATC CCCTCTACCT GACCGGCTTC 
TTCGGAGGAT ACATCTTGGG GGGCAGCCTA GGAATGGGCC AGTTACTCCT GCGGGCCAAA 
GCCATGCGGC TGCTGTACTA CCTGAAGACC GAGGACCCTG AGTACGACGT GCAGAGCAAG 
CAGTGGCTCA CCCATTTGCT CGATCAATTT ACCAACATTA AGAACATCTT GGCCTTGAAA 
AAAATTGAGG TAGTCCACTT TACATCGCTT TCCAGACAAC TGGAATTTGA GGCAACTTCT 
GTGACTGTGA TCCCTGTGTT TCACCTGGCA TACATTCTCA TCATTCTGTT TGCAGTCACA 
TCATGCTTTA GGTTTGACTG CATACGAAAC AAAATGTGTG TTGCGGCCTT TGGAGTGATT 
TCTGCTTTCT TGGCAGTGGT GAGCGGCTTT GGCCTGCTGT TGCACATTGG GGTGCCATTT 
GTCATCATAG TTGCCAATTC ACCATTTCTT ATTCTAGGTG TTGGGGTCGA TGACATGTTT 
ATCATGATTT CTGCCTGGCA TAAGACCAAC CTTGCAGATG ACATACGAGA GCGGATGTCC 
AATGTCTATT CAAAAGCGGC AGTGTCTATT ACAATCACCA CCATCACTAA CATCCTGGCC 
TTATATACAG GGATTATGAG CTCTTTTAGG TCTGTACAAT GTTTTTGCAT CTATACAGGA 
ATGACCCTGT TATTTTGCTA TTTTTATAAC ATCACGTGTT TTGGAGCATT TATGGCCTTG 
GATGGTAAAA GAGAAGTAGT CTGCCTATGC TGGTTGAAAA AGGCTGACCC AAAATGGCCC 
TCATTTAAAA AGTTCTGCTG TTTCCCATTT GGTTCTGTCC CAGATGAACA TGGAACTGAT 
ATCCATCCAA TAAGTTTGTT TTTTAGAGAC TATTTTGGCC CCTTTCTCAC AAGGAGTGAG 
TCCAAGTATT TTGTAGTCTT TATATATGTT TTGTACATCA TAAGCAGTAT ATATGGGTGT 
TTCCATGTGC AGGAAGGTTT AGACCTTCGA AATCTGGCAA GTGACGATTC CTACATCACA 
CCATATTTTA ACGTAGAGGA GAATTATTTT TCAGATTATG GTCCCAGGGT TATGGTTATT 
GTTACTAAAA AAGTTGACTA CTGGGATAAA GATGTTAGGC AAAAACTGGA AAACTGTACT 
AAAATTTTTG AAAAAAATGT CTATGTAGAT AAAAATCTTA CAGAGTTTTG GTTAGATGCA 
TATGTGCAAT ATTTAAAAGG TAACAGCCAA GATCCTAATG AGAAGAATAC TTTTATGAAC 
AATATTCCTG ATTTTTTAAG CAATTTTCCA AATTTTCAGC ATGATATTAA TATTTCTTCA 
TCAAATGAAA TCATTTCTTC CCGGGGCTTC ATTCAGACAA CAGATGTTTC TTCCTCAGCC 
AAAAAGAAAA TATTGTTATT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human PTCHD3 nulls: rare copy number and sequence variants suggest a non-essential gene.
BMC medical genetics1245(2011 Mar)
Ghahramani Seno MM,Kwan BY,Lee-Ng KK,Moessner R,Lionel AC,Marshall CR,Scherer SW

Male germ cell-specific expression of a novel Patched-domain containing gene Ptchd3.
Biochemical and biophysical research communications363(3)757-61(2007 Nov)
Fan J,Akabane H,Zheng X,Zhou X,Zhang L,Liu Q,Zhang YL,Yang J,Zhu GZ

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PTCHD3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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