Gene Symbol | ITPR3 |
Entrez Gene ID | 3710 |
Full Name | inositol 1,4,5-trisphosphate receptor type 3 |
Synonyms | IP3R,IP3R3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010]. |
Disorder MIM: | |
Disorder Html: | {Diabetes, type 1, susceptibility to}, 222100 (2) |