ITPKB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITPKB
Entrez Gene ID	3707
Full Name	inositol-trisphosphate 3-kinase B
Synonyms	IP3-3KB,IP3K,IP3K-B,IP3KB,PIG37
General protein information	Preferred Names inositol-trisphosphate 3-kinase B Names inositol-trisphosphate 3-kinase B IP3 3-kinase B IP3K B inositol 1,4,5-trisphosphate 3-kinase B insP 3-kinase B proliferation-inducing protein 37
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q42.12
Summary	The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008].
Disorder MIM:	147522

mRNA and Protein(s)

mRNA	Protein	Name
XM_005273120.2	XP_005273177.1	inositol-trisphosphate 3-kinase B isoform X2
XM_017001211.1	XP_016856700.1	inositol-trisphosphate 3-kinase B isoform X1
XM_017001211.2	XP_016856700.1	inositol-trisphosphate 3-kinase B isoform X1
XM_005273120.3	XP_005273177.1	inositol-trisphosphate 3-kinase B isoform X2
NM_002221.3	NP_002212.3	inositol-trisphosphate 3-kinase B

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	itpkb	XP_002938890.1
Homo sapiens (human)	ITPKB	NP_002212.3
	ITPKB	XP_001089824.2
Mus musculus (house mouse)	Itpkb	NP_001074644.1
Drosophila melanogaster (fruit fly)	IP3K2	NP_001096969.1
Canis lupus familiaris (dog)	ITPKB	XP_547504.2
Bos taurus (cattle)	ITPKB	XP_002707781.2
Danio rerio (zebrafish)	itpkb	XP_691475.2
Pan troglodytes (chimpanzee)	ITPKB	XP_001141610.1
Rattus norvegicus (Norway rat)	Itpkb	NP_062185.2
Gallus gallus (chicken)	ITPKB	XP_415039.2

Gene Ontology
Bibliography

Related articles in PubMed

miR-140-5p attenuates chemotherapeutic drug-induced cell death by regulating autophagy through inositol 1,4,5-trisphosphate kinase 2 (IP3k2) in human osteosarcoma cells.
Wei R, Cao G, Deng Z, Su J, Cai L
Bioscience reports36(5)(2016 Oct)

miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain.
Salta E, Sierksma A, Vanden Eynden E, De Strooper B
EMBO molecular medicine8(9)1005-18(2016 09)

Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology.
Stygelbout V, Leroy K, Pouillon V, Ando K, D'Amico E, Jia Y, Luo HR, Duyckaerts C, Erneux C, Schurmans S, Brion JP
Brain : a journal of neurology137(Pt 2)537-52(2014 Feb)

Headpiece domain of dematin regulates calcium mobilization and signaling in platelets.
Wieschhaus AJ, Le Breton GC, Chishti AH
The Journal of biological chemistry287(49)41218-31(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

miR-140-5p regulates this context-specific autophagy through its target, inositol 1,4,5-trisphosphate kinase 2 (IP3k2). Therefore, the results of the present study demonstrated that miR-140-5p mediated drug-resistance in osteosarcoma cells by inducing autophagy.
Title: miR-140-5p attenuates chemotherapeutic drug-induced cell death by regulating autophagy through inositol 1,4,5-trisphosphate kinase 2 (IP3k2) in human osteosarcoma cells.

The authors confirm downregulation of miR-132 and upregulation of ITPKB in three distinct human Alzheimer's disease patient cohorts.
Title: miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain.

ITPKB is increased in Alzheimer's brain three-fold in the cerebral cortex of most patients with Alzheimer's disease compared with control subjects and accumulates in dystrophic neurites associated with amyloid plaques.
Title: Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology.

a specific increase in inositol 1,4,5-trisphosphate 3-kinase A and B (ITPKA and ITPKB) was observed upon hESCs spontaneous differentiation.
Title: A specific increase in inositol 1,4,5-trisphosphate 3-kinase B expression upon differentiation of human embryonic stem cells.

IP3KB not only regulates cytoplasmic Ca(2+) signals by phosphorylation of subplasmalemmal and cytoplasmic Ins(1,4,5)P(3) but may also be involved in modulating nuclear Ca(2+) signals generated from these nuclear envelope invaginations.
Title: Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope.

The following ITPKB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITPKB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15820	NM_002221.3 Latest version!	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu35020	XM_005273120.3 Latest version!	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu87352	XM_017001211.2 Latest version!	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu87352	XM_017001211.1	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu35020	XM_005273120.2	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITPKB ( NM_002221.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002212.3 Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), mRNA.

Price & Availability↑

CloneID	OHu15820
Clone ID Related Accession (Same CDS sequence)	NM_002221.3
Accession Version	NM_002221.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2841bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC015009.1, Y18024.2, AJ242780.1, AL365444.11 and AK313801.1. On Jul 16, 2008 this sequence version replaced NM_002221.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AJ242780.1, Y18024.2 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGAGCAAATC ATGGAGGAAG ATAAAAAACA TGGTGCACTG GTCTCCCTTC 
GTCATGTCCT TCAAGAAGAA GTACCCCTGG ATCCAGCTGG CAGGACACGC AGGGAGTTTC 
AAGGCAGCTG CCAATGGCAG GATCCTGAAG AAGCACTGTG AGTCAGAGCA GCGCTGCCTG 
GACCGGCTGA TGGTGGATGT GCTGAGGCCC TTCGTACCTG CCTACCATGG GGATGTGGTG 
AAGGACGGGG AGCGCTACAA CCAGATGGAC GACCTGCTGG CCGACTTCGA CTCGCCCTGT 
GTGATGGACT GCAAGATGGG AATCAGGACC TACCTGGAGG AGGAGCTCAC GAAGGCCCGG 
AAGAAGCCCA GCCTGCGGAA GGACATGTAC CAGAAGATGA TCGAGGTGGA CCCCGAGGCC 
CCCACCGAGG AGGAAAAAGC ACAGCGGGCT GTGACCAAGC CACGGTACAT GCAGTGGCGG 
GAGACCATCA GCTCCACGGC CACCCTGGGG TTCAGGATCG AGGGAATCAA GAAAGAAGAC 
GGCACCGTGA ACCGGGACTT CAAGAAGACC AAAACGAGGG AGCAGGTCAC CGAGGCCTTC 
AGAGAGTTCA CTAAAGGAAA CCATAACATC CTGATCGCCT ATCGGGACCG GCTGAAGGCC 
ATTCGAACCA CTCTAGAAGT TTCTCCCTTC TTCAAGTGCC ACGAGGTCAT TGGCAGCTCC 
CTCCTCTTCA TCCACGACAA GAAGGAACAG GCCAAAGTGT GGATGATCGA CTTTGGGAAA 
ACCACGCCCC TGCCTGAGGG CCAGACCCTG CAGCATGACG TCCCCTGGCA GGAGGGGAAC 
CGGGAGGATG GCTACCTCTC GGGGCTCAAT AACCTCGTCG ACATCCTGAC CGAGATGTCC 
CAGGATGCCC CACTCGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002212.3
CDS	341..3181
Translation	MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA

Target ORF information:

RefSeq Version	NM_002221.3
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002221.3

ORF Insert Sequence:

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGAGCAAATC ATGGAGGAAG ATAAAAAACA TGGTGCACTG GTCTCCCTTC 
GTCATGTCCT TCAAGAAGAA GTACCCCTGG ATCCAGCTGG CAGGACACGC AGGGAGTTTC 
AAGGCAGCTG CCAATGGCAG GATCCTGAAG AAGCACTGTG AGTCAGAGCA GCGCTGCCTG 
GACCGGCTGA TGGTGGATGT GCTGAGGCCC TTCGTACCTG CCTACCATGG GGATGTGGTG 
AAGGACGGGG AGCGCTACAA CCAGATGGAC GACCTGCTGG CCGACTTCGA CTCGCCCTGT 
GTGATGGACT GCAAGATGGG AATCAGGACC TACCTGGAGG AGGAGCTCAC GAAGGCCCGG 
AAGAAGCCCA GCCTGCGGAA GGACATGTAC CAGAAGATGA TCGAGGTGGA CCCCGAGGCC 
CCCACCGAGG AGGAAAAAGC ACAGCGGGCT GTGACCAAGC CACGGTACAT GCAGTGGCGG 
GAGACCATCA GCTCCACGGC CACCCTGGGG TTCAGGATCG AGGGAATCAA GAAAGAAGAC 
GGCACCGTGA ACCGGGACTT CAAGAAGACC AAAACGAGGG AGCAGGTCAC CGAGGCCTTC 
AGAGAGTTCA CTAAAGGAAA CCATAACATC CTGATCGCCT ATCGGGACCG GCTGAAGGCC 
ATTCGAACCA CTCTAGAAGT TTCTCCCTTC TTCAAGTGCC ACGAGGTCAT TGGCAGCTCC 
CTCCTCTTCA TCCACGACAA GAAGGAACAG GCCAAAGTGT GGATGATCGA CTTTGGGAAA 
ACCACGCCCC TGCCTGAGGG CCAGACCCTG CAGCATGACG TCCCCTGGCA GGAGGGGAAC 
CGGGAGGATG GCTACCTCTC GGGGCTCAAT AACCTCGTCG ACATCCTGAC CGAGATGTCC 
CAGGATGCCC CACTCGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITPKB ( XM_005273120.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005273177.1 Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu35020
Clone ID Related Accession (Same CDS sequence)	XM_005273120.2 , XM_005273120.3
Accession Version	XM_005273120.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005273120.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005273177.1
CDS	493..2427
Translation	MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRV

Target ORF information:

RefSeq Version	XM_005273120.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005273120.2

ORF Insert Sequence:

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITPKB ( XM_005273120.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005273177.1 Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X2, mRNA.

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CloneID	OHu35020
Clone ID Related Accession (Same CDS sequence)	XM_005273120.2 , XM_005273120.3
Accession Version	XM_005273120.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005273120.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005273177.1
CDS	462..2396
Translation	MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRV

Target ORF information:

RefSeq Version	XM_005273120.3
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005273120.3

ORF Insert Sequence:

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITPKB ( XM_017001211.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856700.1 Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu87352
Clone ID Related Accession (Same CDS sequence)	XM_017001211.1 , XM_017001211.2
Accession Version	XM_017001211.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGGTGGAGTC TCGCTCTGTC ACCCAGGCTG GAGTGCAGTG GCATGATATC 
GGCTCACTGC AACCTCTGCC TCCCGGATTC AAGCAATTCT CCCGCCTCAG CCTTCCGAAT 
AGCTGGGACT ACAGGCGCAT GCCACCATGC CCGGATAATT TTTGTATTTT TAGTAGAAAT 
GGGTTTTCAC CATGTTGGCC AGGATGGTCT CTATCTCTTG ATCTTGTGAT ACTCCCATCT 
CGGCCTCCCA AAGTGCTGGG ATTACAGGCG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856700.1
CDS	493..2685
Translation	MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVVESRSVTQAGVQWHDIGSLQPLPPGFKQFSRLSLPNSWDYRRMPPCPDNFCIFSRNGFSPCWPGWSLSLDLVILPSRPPKVLGLQA

Target ORF information:

RefSeq Version	XM_017001211.1
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001211.1

ORF Insert Sequence:

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGGTGGAGTC TCGCTCTGTC ACCCAGGCTG GAGTGCAGTG GCATGATATC 
GGCTCACTGC AACCTCTGCC TCCCGGATTC AAGCAATTCT CCCGCCTCAG CCTTCCGAAT 
AGCTGGGACT ACAGGCGCAT GCCACCATGC CCGGATAATT TTTGTATTTT TAGTAGAAAT 
GGGTTTTCAC CATGTTGGCC AGGATGGTCT CTATCTCTTG ATCTTGTGAT ACTCCCATCT 
CGGCCTCCCA AAGTGCTGGG ATTACAGGCG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITPKB ( XM_017001211.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856700.1 Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu87352
Clone ID Related Accession (Same CDS sequence)	XM_017001211.1 , XM_017001211.2
Accession Version	XM_017001211.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	inositol-trisphosphate 3-kinase B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017001211.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGGTGGAGTC TCGCTCTGTC ACCCAGGCTG GAGTGCAGTG GCATGATATC 
GGCTCACTGC AACCTCTGCC TCCCGGATTC AAGCAATTCT CCCGCCTCAG CCTTCCGAAT 
AGCTGGGACT ACAGGCGCAT GCCACCATGC CCGGATAATT TTTGTATTTT TAGTAGAAAT 
GGGTTTTCAC CATGTTGGCC AGGATGGTCT CTATCTCTTG ATCTTGTGAT ACTCCCATCT 
CGGCCTCCCA AAGTGCTGGG ATTACAGGCG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856700.1
CDS	462..2654
Translation	MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVVESRSVTQAGVQWHDIGSLQPLPPGFKQFSRLSLPNSWDYRRMPPCPDNFCIFSRNGFSPCWPGWSLSLDLVILPSRPPKVLGLQA

Target ORF information:

RefSeq Version	XM_017001211.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001211.2

ORF Insert Sequence:

ATGGCTGTGT ACTGCTATGC GCTCAATAGC CTGGTGATCA TGAATAGCGC CAACGAGATG 
AAGAGCGGCG GCGGCCCGGG GCCCAGTGGC AGCGAGACGC CCCCGCCCCC GAGGAGGGCA 
GTGCTGAGCC CCGGCAGCGT TTTCAGCCCC GGGAGAGGCG CCTCTTTCCT CTTCCCCCCA 
GCCGAGTCGC TGTCCCCCGA GGAGCCCCGG AGCCCCGGGG GCTGGCGGAG CGGCCGGCGC 
AGGCTGAATA GTAGCAGCGG CAGTGGCAGC GGCAGCAGCG GCAGTAGCGT GAGCAGCCCA 
AGTTGGGCTG GTCGCCTGCG AGGGGACCGG CAGCAGGTGG TGGCAGCCGG TACCCTCTCC 
CCGCCAGGGC CGGAGGAGGC CAAGAGGAAG CTGCGGATCT TGCAGCGCGA GTTGCAGAAC 
GTGCAGGTGA ACCAGAAAGT GGGCATGTTT GAGGCGCACA TCCAGGCACA GAGCTCCGCC 
ATTCAAGCGC CCCGCAGCCC GCGTTTGGGC AGGGCTCGCT CGCCCTCCCC GTGCCCCTTC 
CGCAGCAGCA GTCAGCCCCC TGGAAGGGTC CTGGTTCAGG GCGCCCGGAG CGAGGAACGG 
AGGACAAAGT CCTGGGGGGA GCAATGTCCA GAGACTTCAG GAACCGACTC CGGGAGGAAA 
GGAGGGCCCA GCCTATGCTC CTCGCAGGTG AAGAAAGGAA TGCCACCTCT TCCCGGCCGG 
GCTGCCCCTA CAGGATCAGA GGCTCAGGGT CCATCCGCTT TTGTAAGGAT GGAGAAGGGT 
ATCCCTGCCA GTCCCCGCTG TGGCTCACCC ACAGCTATGG AAATTGACAA AAGGGGCTCT 
CCTACCCCGG GAACTCGGAG CTGCCTAGCT CCCTCATTGG GGCTGTTCGG AGCTAGCTTA 
ACGATGGCCA CGGAAGTGGC AGCGAGAGTT ACATCCACTG GGCCACACCG TCCACAGGAT 
CTTGCCCTCA CTGAGCCGTC TGGGAGAGCC CGTGAGCTTG AGGACCTGCA GCCCCCAGAG 
GCCCTGGTGG AGAGGCAGGG GCAGTTTCTG GGCAGTGAGA CAAGCCCAGC CCCAGAAAGG 
GGCGGGCCCC GCGATGGAGA ACCCCCTGGG AAGATGGGGA AAGGATATCT GCCCTGTGGC 
ATGCCGGGCT CTGGGGAGCC TGAAGTGGGC AAAAGGCCAG AGGAGACGAC TGTGAGCGTG 
CAAAGCGCAG AGTCCTCTGA TTCCCTGAGC TGGTCCAGGC TGCCCAGGGC CCTGGCCTCC 
GTAGGCCCTG AGGAGGCCCG AAGTGGGGCC CCCGTGGGCG GGGGGCGTTG GCAGCTCTCC 
GACAGAGTGG AGGGAGGGTC CCCAACGCTG GGCTTGCTTG GGGGCAGCCC CTCAGCACAG 
CCGGGGACCG GGAATGTGGA GGCGGGAATT CCTTCTGGCA GAATGCTGGA GCCTTTGCCC 
TGTTGGGACG CTGCGAAAGA TCTGAAAGAA CCTCAGTGCC CTCCTGGGGA CAGGGTGGGT 
GTGCAGCCTG GGAACTCCAG GGTTTGGCAG GGCACCATGG AGAAAGCCGG TTTGGCTTGG 
ACGCGTGGCA CAGGGGTGCA ATCAGAGGGG ACTTGGGAAA GCCAGCGGCA GGACAGTGAT 
GCCCTCCCAA GTCCGGAGCT GCTACCCCAA GATCCGGACA AGCCTTTCCT GAGGAAGGCC 
TGCAGCCCCA GCAACATACC TGCTGTCATC ATTACAGACA TGGGCACCCA GGAGGATGGG 
GCCTTGGAGG AGACGCAGGG AAGCCCTCGG GGCAACCTGC CCCTGAGGAA ACTGTCCTCT 
TCCTCGGCCT CCTCCACGGG CTTCTCCTCA TCCTACGAAG ACTCAGAGGA GGACATCTCC 
AGTGACCCTG AGCGCACCCT GGACCCCAAC TCAGCCTTCC TGCATACCCT GGACCAGCAG 
AAACCTAGAG TGGTGGAGTC TCGCTCTGTC ACCCAGGCTG GAGTGCAGTG GCATGATATC 
GGCTCACTGC AACCTCTGCC TCCCGGATTC AAGCAATTCT CCCGCCTCAG CCTTCCGAAT 
AGCTGGGACT ACAGGCGCAT GCCACCATGC CCGGATAATT TTTGTATTTT TAGTAGAAAT 
GGGTTTTCAC CATGTTGGCC AGGATGGTCT CTATCTCTTG ATCTTGTGAT ACTCCCATCT 
CGGCCTCCCA AAGTGCTGGG ATTACAGGCG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

miR-140-5p attenuates chemotherapeutic drug-induced cell death by regulating autophagy through inositol 1,4,5-trisphosphate kinase 2 (IP3k2) in human osteosarcoma cells.
Bioscience reports36(5)(2016 Oct)
Wei R,Cao G,Deng Z,Su J,Cai L

miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain.
EMBO molecular medicine8(9)1005-18(2016 09)
Salta E,Sierksma A,Vanden Eynden E,De Strooper B

Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology.
Brain : a journal of neurology137(Pt 2)537-52(2014 Feb)
Stygelbout V,Leroy K,Pouillon V,Ando K,D'Amico E,Jia Y,Luo HR,Duyckaerts C,Erneux C,Schurmans S,Brion JP

Headpiece domain of dematin regulates calcium mobilization and signaling in platelets.
The Journal of biological chemistry287(49)41218-31(2012 Nov)
Wieschhaus AJ,Le Breton GC,Chishti AH

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ITPKB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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