Gene Symbol | ITGB2 |
Entrez Gene ID | 3689 |
Full Name | integrin subunit beta 2 |
Synonyms | CD18,LAD,LCAMB,LFA-1,MAC-1,MF17,MFI7 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]. |
Disorder MIM: | |
Disorder Html: | Leukocyte adhesion deficiency, 116920 (3) |