ITGA9 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITGA9
Entrez Gene ID	3680
Full Name	integrin subunit alpha 9
Synonyms	ALPHA-RLC,ITGA4L,RLC
General protein information	Preferred Names integrin subunit alpha 9 Names integrin alpha-9 integrin alpha-RLC
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p22.2
Summary	This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008].
Disorder MIM:	603963

mRNA and Protein(s)

mRNA	Protein	Name
NM_002207.2	NP_002198.2	integrin alpha-9 precursor
NM_002207.3	NP_002198.2	integrin alpha-9 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Itga9	XP_006244235.1
Danio rerio (zebrafish)	itga9	XP_001919452.4
Homo sapiens (human)	ITGA9	NP_002198.2
Bos taurus (cattle)	ITGA9	NP_001179647.1
Gallus gallus (chicken)	ITGA9	NP_001012876.1
Xenopus tropicalis (tropical clawed frog)	itga9	XP_004915411.1
Pan troglodytes (chimpanzee)	ITGA9	XP_526172.3
Mus musculus (house mouse)	Itga9	NP_598482.2
Canis lupus familiaris (dog)	ITGA9	XP_005634304.1

Gene Ontology
Bibliography

Related articles in PubMed

Constitutive Activation of Integrin ?9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis.
Emori T, Hirose J, Ise K, Yomoda JI, Kasahara M, Shinkuma T, Yoshitomi H, Ito H, Hashimoto M, Sugahara S, Fujita H, Yamamoto N, Morita Y, Narumiya S, Aramori I
Journal of immunology (Baltimore, Md. : 1950)199(10)3427-3436(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Metastatic prostate cancer cells cultured on osteo-mimetic surfaces coated with tenascin C exhibited enhanced adhesion and colony formation as mediated by integrin alpha9beta1.
Title: Tenascin-C and Integrin ?9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment.

this study demonstrates the central role of alpha9 in pathogenic behaviors of rheumatoid arthritis fibroblast-like synoviocytes
Title: Constitutive Activation of Integrin ?9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis.

findings identify a novel physiological context for combinatorial integrin signaling, laying the foundation for therapeutic strategies that manipulate alpha9beta1 and/or alpha3beta1 during wound healing
Title: Suppression of integrin ?3?1 by ?9?1 in the epidermis controls the paracrine resolution of wound angiogenesis.

the expression levels of DLEC1 and ITGA9 were prominently decreased in lung tumor samples
Title: Expression level and methylation status of three tumor suppressor genes, DLEC1, ITGA9 and MLH1, in non-small cell lung cancer.

our results demonstrate that upregulation of ITGA9 in response to the decrease in miR-125b in metastatic melanoma is responsible for melanoma tumor cell migration and invasion.
Title: MicroRNA-125b suppresses the epithelial-mesenchymal transition and cell invasion by targeting ITGA9 in melanoma.

The following ITGA9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITGA9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18458	NM_002207.3 Latest version!	Homo sapiens integrin subunit alpha 9 (ITGA9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00
View Old Accession Versions >>
OHu18458	NM_002207.2	Homo sapiens integrin subunit alpha 9 (ITGA9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITGA9 ( NM_002207.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002198.2 Homo sapiens integrin subunit alpha 9 (ITGA9), mRNA.

Price & Availability↑

CloneID	OHu18458
Clone ID Related Accession (Same CDS sequence)	NM_002207.2 , NM_002207.3
Accession Version	NM_002207.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3108bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	integrin alpha-9 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC030198.1, AC092055.2, D25303.1, L24158.1 and BX647350.1. This sequence is a reference standard in the RefSeqGene project. On Sep 22, 2004 this sequence version replaced NM_002207.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D25303.1, L24158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147920, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCGGCC CGGCTGCGCC GAGGGGCGCC GGGAGGCTCC GCGCGCTGCT GCTGGCGCTG 
GTGGTCGCGG GGATCCCCGC GGGCGCCTAC AACCTCGACC CGCAGCGCCC CGTGCACTTC 
CAGGGCCCCG CTGACTCGTT CTTCGGCTAC GCAGTTCTGG AGCATTTCCA CGACAACACG 
CGCTGGGTCC TTGTGGGCGC ACCAAAGGCA GATTCCAAAT ACAGCCCTTC AGTGAAGTCT 
CCTGGGGCTG TGTTTAAGTG CCGTGTTCAC ACCAACCCTG ACCGGAGATG CACCGAACTG 
GACATGGCTC GAGGGAAGAA TCGGGGCACG TCCTGCGGAA AGACCTGCCG GGAAGACCGC 
GATGATGAGT GGATGGGGGT GAGCCTGGCC CGACAGCCCA AGGCTGATGG CCGTGTGTTG 
GCCTGTGCTC ATCGCTGGAA GAACATCTAC TATGAAGCCG ACCACATCCT ACCCCATGGC 
TTCTGCTACA TCATCCCCTC CAACCTCCAG GCCAAAGGCA GGACGCTGAT CCCTTGCTAT 
GAAGAGTATA AGAAGAAGTA CGGAGAGGAA CACGGCTCCT GCCAGGCTGG GATAGCGGGC 
TTCTTCACCG AGGAGCTGGT GGTGATGGGT GCTCCAGGGT CATTTTATTG GGCTGGAACC 
ATCAAAGTGC TGAACCTTAC GGACAACACC TATTTAAAAC TGAACGACGA AGTGATCATG 
AACAGGCGGT ACACCTACCT GGGCTACGCA GTGACCGCTG GCCACTTCTC TCACCCGTCC 
ACCATTGATG TGGTAGGAGG TGCCCCACAG GACAAAGGCA TCGGCAAGGT TTATATTTTC 
AGAGCTGACC GAAGATCAGG CACCTTAATT AAGATCTTTC AAGCATCAGG TAAAAAGATG 
GGCTCTTACT TCGGCTCCTC CTTGTGCGCA GTTGACCTGA ATGGGGACGG CCTCTCTGAC 
CTGCTGGTGG GGGCCCCCAT GTTTTCTGAG ATCAGGGATG AGGGACAGGT CACTGTCTAC 
ATCAACAGAG GAAATGGAGC CCTCGAGGAG CAGCTGGCTC TGACTGGGGA TGGTGCCTAC 
AATGCGCACT TTGGAGAGAG CATTGCCAGC CTGGACGATC TGGACAATGA TGGGTTCCCA 
GATGTGGCCA TTGGTGCACC CAAGGAGGAT GACTTCGCAG GGGCGGTCTA TATCTATCAT 
GGTGATGCCG GTGGGATAGT CCCTCAGTAC TCAATGAAAC TGTCTGGGCA GAAGATAAAT 
CCAGTGCTCC GGATGTTTGG TCAGTCCATA TCGGGAGGCA TTGATATGGA TGGAAATGGC 
TATCCTGATG TCACTGTTGG AGCCTTCATG TCCGACAGCG TGGTTCTTCT CAGAGCAAGG 
CCTGTCATTA CGGTGGATGT CTCCATCTTC CTCCCGGGCT CCATCAACAT CACAGCGCCT 
CAGTGTCACG ACGGACAGCA GCCTGTGAAC TGCCTGAACG TCACCACCTG CTTCAGCTTC 
CATGGCAAAC ACGTTCCAGG AGAGATTGGC CTGAATTATG TTCTGATGGC TGACGTGGCC 
AAAAAGGAGA AGGGCCAGAT GCCCAGGGTC TACTTTGTGC TGCTGGGAGA GACCATGGGT 
CAGGTCACAG AGAAGCTGCA GCTGACTTAC ATGGAGGAGA CGTGTCGTCA CTATGTGGCC 
CATGTGAAGC GGAGGGTGCA GGACGTCATC AGCCCGATCG TGTTTGAAGC AGCCTACAGC 
CTCAGTGAGC ATGTGACTGG AGAGGAGGAG AGGGAACTGC CGCCTCTGAC ACCAGTTCTC 
CGCTGGAAAA AGGGACAAAA GATTGCCCAA AAGAATCAGA CTGTTTTTGA AAGGAATTGC 
CGTTCAGAGG ACTGTGCCGC AGACCTGCAG CTTCAGGGTA AACTGCTGCT CTCCAGTATG 
GATGAGAAAA CCCTGTATCT AGCTTTGGGG GCTGTGAAGA ACATCTCCCT AAACATCTCT 
ATCTCCAACC TCGGAGATGA TGCCTATGAT GCCAACGTGT CCTTCAATGT TTCCCGGGAG 
CTCTTCTTCA TCAACATGTG GCAGAAGGAG GAGATGGGCA TCTCCTGTGA GCTGCTGGAA 
TCGGACTTCC TCAAATGCAG CGTGGGATTT CCTTTCATGA GGTCAAAGTC AAAGTATGAA 
TTCAGCGTGA TCTTTGATAC AAGCCACCTG TCTGGGGAAG AGGAAGTTCT CAGCTTCATT 
GTTACTGCTC AGAGTGGCAA CACGGAGCGC TCTGAATCCC TGCATGACAA CACCCTCGTG 
CTGATGGTGC CACTGATGCA CGAGGTGGAC ACGTCCATCA CCGGAATCAT GTCTCCAACC 
TCCTTTGTAT ATGGCGAGTC CGTGGACGCA GCCAACTTCA TTCAGCTGGA TGACCTGGAG 
TGTCACTTTC AGCCCATCAA TATCACCCTT CAGGTCTACA ACACTGGCCC AAGCACCCTT 
CCAGGGTCAT CTGTCAGCAT CTCTTTCCCT AATCGACTCT CATCTGGTGG TGCAGAGATG 
TTTCATGTCC AGGAAATGGT GGTGGGCCAA GAGAAGGGAA ACTGCTCTTT CCAGAAAAAC 
CCAACTCCCT GCATCATCCC TCAAGAACAA GAAAATATCT TCCACACAAT ATTTGCTTTT 
TTCACAAAGT CTGGAAGAAA AGTCTTGGAC TGTGAAAAAC CAGGAATTTC TTGCCTAACA 
GCACACTGTA ACTTTAGTGC TCTTGCTAAA GAAGAAAGTC GTACTATAGA CATTTACATG 
CTGCTGAACA CAGAAATACT GAAAAAGGAC AGTTCGTCTG TCATCCAGTT CATGTCCCGC 
GCCAAGGTGA AGGTGGATCC TGCCCTAAGG GTGGTGGAAA TAGCTCATGG GAACCCAGAA 
GAGGTGACGG TGGTCTTCGA GGCCCTGCAC AATCTGGAGC CCCGTGGCTA CGTCGTGGGG 
TGGATCATCG CCATCAGTTT GTTGGTGGGA ATCCTCATCT TCCTGCTGCT GGCCGTGCTG 
CTCTGGAAGA TGGGCTTCTT TCGCCGAAGG TACAAAGAAA TTATCGAAGC TGAGAAGAAC 
CGGAAAGAGA ATGAAGACAG TTGGGACTGG GTCCAGAAAA ACCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002198.2
CDS	54..3161
Translation	MGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDSWDWVQKNQ

Target ORF information:

RefSeq Version	NM_002207.2
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha 9 (ITGA9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002207.2

ORF Insert Sequence:

ATGGGCGGCC CGGCTGCGCC GAGGGGCGCC GGGAGGCTCC GCGCGCTGCT GCTGGCGCTG 
GTGGTCGCGG GGATCCCCGC GGGCGCCTAC AACCTCGACC CGCAGCGCCC CGTGCACTTC 
CAGGGCCCCG CTGACTCGTT CTTCGGCTAC GCAGTTCTGG AGCATTTCCA CGACAACACG 
CGCTGGGTCC TTGTGGGCGC ACCAAAGGCA GATTCCAAAT ACAGCCCTTC AGTGAAGTCT 
CCTGGGGCTG TGTTTAAGTG CCGTGTTCAC ACCAACCCTG ACCGGAGATG CACCGAACTG 
GACATGGCTC GAGGGAAGAA TCGGGGCACG TCCTGCGGAA AGACCTGCCG GGAAGACCGC 
GATGATGAGT GGATGGGGGT GAGCCTGGCC CGACAGCCCA AGGCTGATGG CCGTGTGTTG 
GCCTGTGCTC ATCGCTGGAA GAACATCTAC TATGAAGCCG ACCACATCCT ACCCCATGGC 
TTCTGCTACA TCATCCCCTC CAACCTCCAG GCCAAAGGCA GGACGCTGAT CCCTTGCTAT 
GAAGAGTATA AGAAGAAGTA CGGAGAGGAA CACGGCTCCT GCCAGGCTGG GATAGCGGGC 
TTCTTCACCG AGGAGCTGGT GGTGATGGGT GCTCCAGGGT CATTTTATTG GGCTGGAACC 
ATCAAAGTGC TGAACCTTAC GGACAACACC TATTTAAAAC TGAACGACGA AGTGATCATG 
AACAGGCGGT ACACCTACCT GGGCTACGCA GTGACCGCTG GCCACTTCTC TCACCCGTCC 
ACCATTGATG TGGTAGGAGG TGCCCCACAG GACAAAGGCA TCGGCAAGGT TTATATTTTC 
AGAGCTGACC GAAGATCAGG CACCTTAATT AAGATCTTTC AAGCATCAGG TAAAAAGATG 
GGCTCTTACT TCGGCTCCTC CTTGTGCGCA GTTGACCTGA ATGGGGACGG CCTCTCTGAC 
CTGCTGGTGG GGGCCCCCAT GTTTTCTGAG ATCAGGGATG AGGGACAGGT CACTGTCTAC 
ATCAACAGAG GAAATGGAGC CCTCGAGGAG CAGCTGGCTC TGACTGGGGA TGGTGCCTAC 
AATGCGCACT TTGGAGAGAG CATTGCCAGC CTGGACGATC TGGACAATGA TGGGTTCCCA 
GATGTGGCCA TTGGTGCACC CAAGGAGGAT GACTTCGCAG GGGCGGTCTA TATCTATCAT 
GGTGATGCCG GTGGGATAGT CCCTCAGTAC TCAATGAAAC TGTCTGGGCA GAAGATAAAT 
CCAGTGCTCC GGATGTTTGG TCAGTCCATA TCGGGAGGCA TTGATATGGA TGGAAATGGC 
TATCCTGATG TCACTGTTGG AGCCTTCATG TCCGACAGCG TGGTTCTTCT CAGAGCAAGG 
CCTGTCATTA CGGTGGATGT CTCCATCTTC CTCCCGGGCT CCATCAACAT CACAGCGCCT 
CAGTGTCACG ACGGACAGCA GCCTGTGAAC TGCCTGAACG TCACCACCTG CTTCAGCTTC 
CATGGCAAAC ACGTTCCAGG AGAGATTGGC CTGAATTATG TTCTGATGGC TGACGTGGCC 
AAAAAGGAGA AGGGCCAGAT GCCCAGGGTC TACTTTGTGC TGCTGGGAGA GACCATGGGT 
CAGGTCACAG AGAAGCTGCA GCTGACTTAC ATGGAGGAGA CGTGTCGTCA CTATGTGGCC 
CATGTGAAGC GGAGGGTGCA GGACGTCATC AGCCCGATCG TGTTTGAAGC AGCCTACAGC 
CTCAGTGAGC ATGTGACTGG AGAGGAGGAG AGGGAACTGC CGCCTCTGAC ACCAGTTCTC 
CGCTGGAAAA AGGGACAAAA GATTGCCCAA AAGAATCAGA CTGTTTTTGA AAGGAATTGC 
CGTTCAGAGG ACTGTGCCGC AGACCTGCAG CTTCAGGGTA AACTGCTGCT CTCCAGTATG 
GATGAGAAAA CCCTGTATCT AGCTTTGGGG GCTGTGAAGA ACATCTCCCT AAACATCTCT 
ATCTCCAACC TCGGAGATGA TGCCTATGAT GCCAACGTGT CCTTCAATGT TTCCCGGGAG 
CTCTTCTTCA TCAACATGTG GCAGAAGGAG GAGATGGGCA TCTCCTGTGA GCTGCTGGAA 
TCGGACTTCC TCAAATGCAG CGTGGGATTT CCTTTCATGA GGTCAAAGTC AAAGTATGAA 
TTCAGCGTGA TCTTTGATAC AAGCCACCTG TCTGGGGAAG AGGAAGTTCT CAGCTTCATT 
GTTACTGCTC AGAGTGGCAA CACGGAGCGC TCTGAATCCC TGCATGACAA CACCCTCGTG 
CTGATGGTGC CACTGATGCA CGAGGTGGAC ACGTCCATCA CCGGAATCAT GTCTCCAACC 
TCCTTTGTAT ATGGCGAGTC CGTGGACGCA GCCAACTTCA TTCAGCTGGA TGACCTGGAG 
TGTCACTTTC AGCCCATCAA TATCACCCTT CAGGTCTACA ACACTGGCCC AAGCACCCTT 
CCAGGGTCAT CTGTCAGCAT CTCTTTCCCT AATCGACTCT CATCTGGTGG TGCAGAGATG 
TTTCATGTCC AGGAAATGGT GGTGGGCCAA GAGAAGGGAA ACTGCTCTTT CCAGAAAAAC 
CCAACTCCCT GCATCATCCC TCAAGAACAA GAAAATATCT TCCACACAAT ATTTGCTTTT 
TTCACAAAGT CTGGAAGAAA AGTCTTGGAC TGTGAAAAAC CAGGAATTTC TTGCCTAACA 
GCACACTGTA ACTTTAGTGC TCTTGCTAAA GAAGAAAGTC GTACTATAGA CATTTACATG 
CTGCTGAACA CAGAAATACT GAAAAAGGAC AGTTCGTCTG TCATCCAGTT CATGTCCCGC 
GCCAAGGTGA AGGTGGATCC TGCCCTAAGG GTGGTGGAAA TAGCTCATGG GAACCCAGAA 
GAGGTGACGG TGGTCTTCGA GGCCCTGCAC AATCTGGAGC CCCGTGGCTA CGTCGTGGGG 
TGGATCATCG CCATCAGTTT GTTGGTGGGA ATCCTCATCT TCCTGCTGCT GGCCGTGCTG 
CTCTGGAAGA TGGGCTTCTT TCGCCGAAGG TACAAAGAAA TTATCGAAGC TGAGAAGAAC 
CGGAAAGAGA ATGAAGACAG TTGGGACTGG GTCCAGAAAA ACCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ITGA9 ( NM_002207.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002198.2 Homo sapiens integrin subunit alpha 9 (ITGA9), mRNA.

Price & Availability↑

CloneID	OHu18458
Clone ID Related Accession (Same CDS sequence)	NM_002207.2 , NM_002207.3
Accession Version	NM_002207.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3108bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	integrin alpha-9 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC092055.2, BC030198.1, D25303.1, L24158.1, BX647350.1 and AC093415.2. On Nov 22, 2018 this sequence version replaced NM_002207.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D25303.1, L24158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147920, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000264741.10/ ENSP00000264741.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGCGGCC CGGCTGCGCC GAGGGGCGCC GGGAGGCTCC GCGCGCTGCT GCTGGCGCTG 
GTGGTCGCGG GGATCCCCGC GGGCGCCTAC AACCTCGACC CGCAGCGCCC CGTGCACTTC 
CAGGGCCCCG CTGACTCGTT CTTCGGCTAC GCAGTTCTGG AGCATTTCCA CGACAACACG 
CGCTGGGTCC TTGTGGGCGC ACCAAAGGCA GATTCCAAAT ACAGCCCTTC AGTGAAGTCT 
CCTGGGGCTG TGTTTAAGTG CCGTGTTCAC ACCAACCCTG ACCGGAGATG CACCGAACTG 
GACATGGCTC GAGGGAAGAA TCGGGGCACG TCCTGCGGAA AGACCTGCCG GGAAGACCGC 
GATGATGAGT GGATGGGGGT GAGCCTGGCC CGACAGCCCA AGGCTGATGG CCGTGTGTTG 
GCCTGTGCTC ATCGCTGGAA GAACATCTAC TATGAAGCCG ACCACATCCT ACCCCATGGC 
TTCTGCTACA TCATCCCCTC CAACCTCCAG GCCAAAGGCA GGACGCTGAT CCCTTGCTAT 
GAAGAGTATA AGAAGAAGTA CGGAGAGGAA CACGGCTCCT GCCAGGCTGG GATAGCGGGC 
TTCTTCACCG AGGAGCTGGT GGTGATGGGT GCTCCAGGGT CATTTTATTG GGCTGGAACC 
ATCAAAGTGC TGAACCTTAC GGACAACACC TATTTAAAAC TGAACGACGA AGTGATCATG 
AACAGGCGGT ACACCTACCT GGGCTACGCA GTGACCGCTG GCCACTTCTC TCACCCGTCC 
ACCATTGATG TGGTAGGAGG TGCCCCACAG GACAAAGGCA TCGGCAAGGT TTATATTTTC 
AGAGCTGACC GAAGATCAGG CACCTTAATT AAGATCTTTC AAGCATCAGG TAAAAAGATG 
GGCTCTTACT TCGGCTCCTC CTTGTGCGCA GTTGACCTGA ATGGGGACGG CCTCTCTGAC 
CTGCTGGTGG GGGCCCCCAT GTTTTCTGAG ATCAGGGATG AGGGACAGGT CACTGTCTAC 
ATCAACAGAG GAAATGGAGC CCTCGAGGAG CAGCTGGCTC TGACTGGGGA TGGTGCCTAC 
AATGCGCACT TTGGAGAGAG CATTGCCAGC CTGGACGATC TGGACAATGA TGGGTTCCCA 
GATGTGGCCA TTGGTGCACC CAAGGAGGAT GACTTCGCAG GGGCGGTCTA TATCTATCAT 
GGTGATGCCG GTGGGATAGT CCCTCAGTAC TCAATGAAAC TGTCTGGGCA GAAGATAAAT 
CCAGTGCTCC GGATGTTTGG TCAGTCCATA TCGGGAGGCA TTGATATGGA TGGAAATGGC 
TATCCTGATG TCACTGTTGG AGCCTTCATG TCCGACAGCG TGGTTCTTCT CAGAGCAAGG 
CCTGTCATTA CGGTGGATGT CTCCATCTTC CTCCCGGGCT CCATCAACAT CACAGCGCCT 
CAGTGTCACG ACGGACAGCA GCCTGTGAAC TGCCTGAACG TCACCACCTG CTTCAGCTTC 
CATGGCAAAC ACGTTCCAGG AGAGATTGGC CTGAATTATG TTCTGATGGC TGACGTGGCC 
AAAAAGGAGA AGGGCCAGAT GCCCAGGGTC TACTTTGTGC TGCTGGGAGA GACCATGGGT 
CAGGTCACAG AGAAGCTGCA GCTGACTTAC ATGGAGGAGA CGTGTCGTCA CTATGTGGCC 
CATGTGAAGC GGAGGGTGCA GGACGTCATC AGCCCGATCG TGTTTGAAGC AGCCTACAGC 
CTCAGTGAGC ATGTGACTGG AGAGGAGGAG AGGGAACTGC CGCCTCTGAC ACCAGTTCTC 
CGCTGGAAAA AGGGACAAAA GATTGCCCAA AAGAATCAGA CTGTTTTTGA AAGGAATTGC 
CGTTCAGAGG ACTGTGCCGC AGACCTGCAG CTTCAGGGTA AACTGCTGCT CTCCAGTATG 
GATGAGAAAA CCCTGTATCT AGCTTTGGGG GCTGTGAAGA ACATCTCCCT AAACATCTCT 
ATCTCCAACC TCGGAGATGA TGCCTATGAT GCCAACGTGT CCTTCAATGT TTCCCGGGAG 
CTCTTCTTCA TCAACATGTG GCAGAAGGAG GAGATGGGCA TCTCCTGTGA GCTGCTGGAA 
TCGGACTTCC TCAAATGCAG CGTGGGATTT CCTTTCATGA GGTCAAAGTC AAAGTATGAA 
TTCAGCGTGA TCTTTGATAC AAGCCACCTG TCTGGGGAAG AGGAAGTTCT CAGCTTCATT 
GTTACTGCTC AGAGTGGCAA CACGGAGCGC TCTGAATCCC TGCATGACAA CACCCTCGTG 
CTGATGGTGC CACTGATGCA CGAGGTGGAC ACGTCCATCA CCGGAATCAT GTCTCCAACC 
TCCTTTGTAT ATGGCGAGTC CGTGGACGCA GCCAACTTCA TTCAGCTGGA TGACCTGGAG 
TGTCACTTTC AGCCCATCAA TATCACCCTT CAGGTCTACA ACACTGGCCC AAGCACCCTT 
CCAGGGTCAT CTGTCAGCAT CTCTTTCCCT AATCGACTCT CATCTGGTGG TGCAGAGATG 
TTTCATGTCC AGGAAATGGT GGTGGGCCAA GAGAAGGGAA ACTGCTCTTT CCAGAAAAAC 
CCAACTCCCT GCATCATCCC TCAAGAACAA GAAAATATCT TCCACACAAT ATTTGCTTTT 
TTCACAAAGT CTGGAAGAAA AGTCTTGGAC TGTGAAAAAC CAGGAATTTC TTGCCTAACA 
GCACACTGTA ACTTTAGTGC TCTTGCTAAA GAAGAAAGTC GTACTATAGA CATTTACATG 
CTGCTGAACA CAGAAATACT GAAAAAGGAC AGTTCGTCTG TCATCCAGTT CATGTCCCGC 
GCCAAGGTGA AGGTGGATCC TGCCCTAAGG GTGGTGGAAA TAGCTCATGG GAACCCAGAA 
GAGGTGACGG TGGTCTTCGA GGCCCTGCAC AATCTGGAGC CCCGTGGCTA CGTCGTGGGG 
TGGATCATCG CCATCAGTTT GTTGGTGGGA ATCCTCATCT TCCTGCTGCT GGCCGTGCTG 
CTCTGGAAGA TGGGCTTCTT TCGCCGAAGG TACAAAGAAA TTATCGAAGC TGAGAAGAAC 
CGGAAAGAGA ATGAAGACAG TTGGGACTGG GTCCAGAAAA ACCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002198.2
CDS	235..3342
Translation	MGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDSWDWVQKNQ

Target ORF information:

RefSeq Version	NM_002207.3
Organism	Homo sapiens(human)
Definition	Homo sapiens integrin subunit alpha 9 (ITGA9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002207.3

ORF Insert Sequence:

ATGGGCGGCC CGGCTGCGCC GAGGGGCGCC GGGAGGCTCC GCGCGCTGCT GCTGGCGCTG 
GTGGTCGCGG GGATCCCCGC GGGCGCCTAC AACCTCGACC CGCAGCGCCC CGTGCACTTC 
CAGGGCCCCG CTGACTCGTT CTTCGGCTAC GCAGTTCTGG AGCATTTCCA CGACAACACG 
CGCTGGGTCC TTGTGGGCGC ACCAAAGGCA GATTCCAAAT ACAGCCCTTC AGTGAAGTCT 
CCTGGGGCTG TGTTTAAGTG CCGTGTTCAC ACCAACCCTG ACCGGAGATG CACCGAACTG 
GACATGGCTC GAGGGAAGAA TCGGGGCACG TCCTGCGGAA AGACCTGCCG GGAAGACCGC 
GATGATGAGT GGATGGGGGT GAGCCTGGCC CGACAGCCCA AGGCTGATGG CCGTGTGTTG 
GCCTGTGCTC ATCGCTGGAA GAACATCTAC TATGAAGCCG ACCACATCCT ACCCCATGGC 
TTCTGCTACA TCATCCCCTC CAACCTCCAG GCCAAAGGCA GGACGCTGAT CCCTTGCTAT 
GAAGAGTATA AGAAGAAGTA CGGAGAGGAA CACGGCTCCT GCCAGGCTGG GATAGCGGGC 
TTCTTCACCG AGGAGCTGGT GGTGATGGGT GCTCCAGGGT CATTTTATTG GGCTGGAACC 
ATCAAAGTGC TGAACCTTAC GGACAACACC TATTTAAAAC TGAACGACGA AGTGATCATG 
AACAGGCGGT ACACCTACCT GGGCTACGCA GTGACCGCTG GCCACTTCTC TCACCCGTCC 
ACCATTGATG TGGTAGGAGG TGCCCCACAG GACAAAGGCA TCGGCAAGGT TTATATTTTC 
AGAGCTGACC GAAGATCAGG CACCTTAATT AAGATCTTTC AAGCATCAGG TAAAAAGATG 
GGCTCTTACT TCGGCTCCTC CTTGTGCGCA GTTGACCTGA ATGGGGACGG CCTCTCTGAC 
CTGCTGGTGG GGGCCCCCAT GTTTTCTGAG ATCAGGGATG AGGGACAGGT CACTGTCTAC 
ATCAACAGAG GAAATGGAGC CCTCGAGGAG CAGCTGGCTC TGACTGGGGA TGGTGCCTAC 
AATGCGCACT TTGGAGAGAG CATTGCCAGC CTGGACGATC TGGACAATGA TGGGTTCCCA 
GATGTGGCCA TTGGTGCACC CAAGGAGGAT GACTTCGCAG GGGCGGTCTA TATCTATCAT 
GGTGATGCCG GTGGGATAGT CCCTCAGTAC TCAATGAAAC TGTCTGGGCA GAAGATAAAT 
CCAGTGCTCC GGATGTTTGG TCAGTCCATA TCGGGAGGCA TTGATATGGA TGGAAATGGC 
TATCCTGATG TCACTGTTGG AGCCTTCATG TCCGACAGCG TGGTTCTTCT CAGAGCAAGG 
CCTGTCATTA CGGTGGATGT CTCCATCTTC CTCCCGGGCT CCATCAACAT CACAGCGCCT 
CAGTGTCACG ACGGACAGCA GCCTGTGAAC TGCCTGAACG TCACCACCTG CTTCAGCTTC 
CATGGCAAAC ACGTTCCAGG AGAGATTGGC CTGAATTATG TTCTGATGGC TGACGTGGCC 
AAAAAGGAGA AGGGCCAGAT GCCCAGGGTC TACTTTGTGC TGCTGGGAGA GACCATGGGT 
CAGGTCACAG AGAAGCTGCA GCTGACTTAC ATGGAGGAGA CGTGTCGTCA CTATGTGGCC 
CATGTGAAGC GGAGGGTGCA GGACGTCATC AGCCCGATCG TGTTTGAAGC AGCCTACAGC 
CTCAGTGAGC ATGTGACTGG AGAGGAGGAG AGGGAACTGC CGCCTCTGAC ACCAGTTCTC 
CGCTGGAAAA AGGGACAAAA GATTGCCCAA AAGAATCAGA CTGTTTTTGA AAGGAATTGC 
CGTTCAGAGG ACTGTGCCGC AGACCTGCAG CTTCAGGGTA AACTGCTGCT CTCCAGTATG 
GATGAGAAAA CCCTGTATCT AGCTTTGGGG GCTGTGAAGA ACATCTCCCT AAACATCTCT 
ATCTCCAACC TCGGAGATGA TGCCTATGAT GCCAACGTGT CCTTCAATGT TTCCCGGGAG 
CTCTTCTTCA TCAACATGTG GCAGAAGGAG GAGATGGGCA TCTCCTGTGA GCTGCTGGAA 
TCGGACTTCC TCAAATGCAG CGTGGGATTT CCTTTCATGA GGTCAAAGTC AAAGTATGAA 
TTCAGCGTGA TCTTTGATAC AAGCCACCTG TCTGGGGAAG AGGAAGTTCT CAGCTTCATT 
GTTACTGCTC AGAGTGGCAA CACGGAGCGC TCTGAATCCC TGCATGACAA CACCCTCGTG 
CTGATGGTGC CACTGATGCA CGAGGTGGAC ACGTCCATCA CCGGAATCAT GTCTCCAACC 
TCCTTTGTAT ATGGCGAGTC CGTGGACGCA GCCAACTTCA TTCAGCTGGA TGACCTGGAG 
TGTCACTTTC AGCCCATCAA TATCACCCTT CAGGTCTACA ACACTGGCCC AAGCACCCTT 
CCAGGGTCAT CTGTCAGCAT CTCTTTCCCT AATCGACTCT CATCTGGTGG TGCAGAGATG 
TTTCATGTCC AGGAAATGGT GGTGGGCCAA GAGAAGGGAA ACTGCTCTTT CCAGAAAAAC 
CCAACTCCCT GCATCATCCC TCAAGAACAA GAAAATATCT TCCACACAAT ATTTGCTTTT 
TTCACAAAGT CTGGAAGAAA AGTCTTGGAC TGTGAAAAAC CAGGAATTTC TTGCCTAACA 
GCACACTGTA ACTTTAGTGC TCTTGCTAAA GAAGAAAGTC GTACTATAGA CATTTACATG 
CTGCTGAACA CAGAAATACT GAAAAAGGAC AGTTCGTCTG TCATCCAGTT CATGTCCCGC 
GCCAAGGTGA AGGTGGATCC TGCCCTAAGG GTGGTGGAAA TAGCTCATGG GAACCCAGAA 
GAGGTGACGG TGGTCTTCGA GGCCCTGCAC AATCTGGAGC CCCGTGGCTA CGTCGTGGGG 
TGGATCATCG CCATCAGTTT GTTGGTGGGA ATCCTCATCT TCCTGCTGCT GGCCGTGCTG 
CTCTGGAAGA TGGGCTTCTT TCGCCGAAGG TACAAAGAAA TTATCGAAGC TGAGAAGAAC 
CGGAAAGAGA ATGAAGACAG TTGGGACTGG GTCCAGAAAA ACCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Constitutive Activation of Integrin ?9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis.
Journal of immunology (Baltimore, Md. : 1950)199(10)3427-3436(2017 Nov)
Emori T,Hirose J,Ise K,Yomoda JI,Kasahara M,Shinkuma T,Yoshitomi H,Ito H,Hashimoto M,Sugahara S,Fujita H,Yamamoto N,Morita Y,Narumiya S,Aramori I

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ITGA9 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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