AQP9 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AQP9
Entrez Gene ID	366
Full Name	aquaporin 9
Synonyms	AQP-9,HsT17287,SSC1,T17287
General protein information	Preferred Names aquaporin 9 Names aquaporin-9 aquaglyceroporin-9 small solute channel 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q21.3
Summary	The aquaporins are a family of water-selective membrane channels. This gene encodes a member of a subset of aquaporins called the aquaglyceroporins. This protein allows passage of a broad range of noncharged solutes and also stimulates urea transport and osmotic water permeability. This protein may also facilitate the uptake of glycerol in hepatic tissue . The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
Disorder MIM:	602914

mRNA and Protein(s)

mRNA	Protein	Name
NM_001320635.1	NP_001307564.1	aquaporin-9 isoform 2
NM_020980.4	NP_066190.2	aquaporin-9 isoform 1
NM_020980.3	NP_066190.2	aquaporin-9
NM_001320636.1	NP_001307565.1	aquaporin-9 isoform 3
NM_020980.5	NP_066190.2	aquaporin-9 isoform 1
NM_001320635.2	NP_001307564.1	aquaporin-9 isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	AQP9	NP_066190.2
Bos taurus (cattle)	AQP9	NP_001192762.1
Danio rerio (zebrafish)	aqp9a	NP_001028268.1
Canis lupus familiaris (dog)	AQP9	XP_544701.1
Rattus norvegicus (Norway rat)	Aqp9	NP_075249.1
Pan troglodytes (chimpanzee)	AQP9	XP_523087.2
Gallus gallus (chicken)	AQP9	XP_004943833.1
Arabidopsis thaliana (thale cress)	NIP7;1	NP_566271.1
	AQP9	XP_001094912.1
Danio rerio (zebrafish)	aqp9b	NP_001171215.1
Xenopus tropicalis (tropical clawed frog)	aqp9	XP_002937719.1
Mus musculus (house mouse)	Aqp9	NP_071309.1
Eremothecium gossypii	AGOS_ACL068W	NP_983336.2

Gene Ontology
Bibliography

Related articles in PubMed

Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure.
Han X, Huang Q, Liu L, Sha X, Hu B, Liu H
International journal of molecular sciences19(1)(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

pH-dependent substrate permeability, measurements of media alkalization, and proton decoupling that AQP9 acts as a channel for the protonated, neutral monocarboxylic acid species.
Title: Electrostatic attraction of weak monoacid anions increases probability for protonation and passage through aquaporins.

AQP9 is down-regulated in hepatocellular carcinoma and its over-expression suppresses hepatoma cell invasion through inhibiting epithelial-to-mesenchymal transition.
Title: Aquaporin 9 is down-regulated in hepatocellular carcinoma and its over-expression suppresses hepatoma cell invasion through inhibiting epithelial-to-mesenchymal transition.

AQP9 overexpression decreased the protein levels of phosphatidylinositol-3-kinase (PI3K), leading to reduced phosphorylation of Akt, and subsequently the protein levels of forkhead box protein O1 (FOXO1) were increased.
Title: Aquaporin 9 inhibits hepatocellular carcinoma through up-regulating FOXO1 expression.

AQP3 was upregulated, and AQP7 and AQP9 were downregulated in hepatocellular carcinoma. A high expression of AQP3 and low expression of AQP7 was significantly associated with the aggressive features of hepatocellular carcinoma.
Title: Expression and clinical significance of aquaglyceroporins in human hepatocellular carcinoma.

AQP9 is involved in the activation of the ERK pathway in androgen-independent prostate cancer cells.
Title: Effect of AQP9 Expression in Androgen-Independent Prostate Cancer Cell PC3.

The following AQP9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AQP9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18497	NM_020980.5 Latest version!	Homo sapiens aquaporin 9 (AQP9), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu101942	NM_001320636.1 Latest version!	Homo sapiens aquaporin 9 (AQP9), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu101686	NM_001320635.2 Latest version!	Homo sapiens aquaporin 9 (AQP9), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu18497	NM_020980.3	Homo sapiens aquaporin 9 (AQP9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu18497	NM_020980.4	Homo sapiens aquaporin 9 (AQP9), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu101686	NM_001320635.1	Homo sapiens aquaporin 9 (AQP9), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AQP9 ( NM_020980.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_066190.2 Homo sapiens aquaporin 9 (AQP9), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18497
Clone ID Related Accession (Same CDS sequence)	NM_020980.4 , NM_020980.3 , NM_020980.5
Accession Version	NM_020980.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	aquaporin-9 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025431.7, AB008775.1 and AC066616.7. This sequence is a reference standard in the RefSeqGene project. On Mar 2, 2016 this sequence version replaced NM_020980.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB008775.1, SRR1803614.128453.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAGTGGT GGCCACCATG ATACTCCTCA TAATCGTCTT TGCCATCTTT 
GACTCCAGAA ACTTGGGAGC CCCCAGAGGC CTAGAGCCCA TTGCCATCGG CCTCCTGATT 
ATTGTCATTG CTTCCTCCCT GGGACTGAAC AGTGGCTGTG CCATGAACCC AGCTCGAGAC 
CTGAGTCCCA GACTTTTCAC TGCCTTGGCA GGCTGGGGGT TTGAAGTCTT CAGAGCTGGA 
AACAACTTCT GGTGGATTCC TGTAGTGGGC CCTTTGGTTG GTGCTGTCAT TGGAGGCCTC 
ATCTATGTTC TTGTCATTGA AATCCACCAT CCAGAGCCTG ACTCAGTCTT TAAGACAGAA 
CAATCTGAGG ACAAACCAGA GAAATATGAA CTCAGTGTCA TCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066190.2
CDS	371..1258
Translation	MQPEGAEKGKSFKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGAVIGGLIYVLVIEIHHPEPDSVFKTEQSEDKPEKYELSVIM

Target ORF information:

RefSeq Version	NM_020980.4
Organism	Homo sapiens(human)
Definition	Homo sapiens aquaporin 9 (AQP9), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020980.4

ORF Insert Sequence:

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAGTGGT GGCCACCATG ATACTCCTCA TAATCGTCTT TGCCATCTTT 
GACTCCAGAA ACTTGGGAGC CCCCAGAGGC CTAGAGCCCA TTGCCATCGG CCTCCTGATT 
ATTGTCATTG CTTCCTCCCT GGGACTGAAC AGTGGCTGTG CCATGAACCC AGCTCGAGAC 
CTGAGTCCCA GACTTTTCAC TGCCTTGGCA GGCTGGGGGT TTGAAGTCTT CAGAGCTGGA 
AACAACTTCT GGTGGATTCC TGTAGTGGGC CCTTTGGTTG GTGCTGTCAT TGGAGGCCTC 
ATCTATGTTC TTGTCATTGA AATCCACCAT CCAGAGCCTG ACTCAGTCTT TAAGACAGAA 
CAATCTGAGG ACAAACCAGA GAAATATGAA CTCAGTGTCA TCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AQP9 ( NM_020980.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_066190.2 Homo sapiens aquaporin 9 (AQP9), mRNA.

Price & Availability↑

CloneID	OHu18497
Clone ID Related Accession (Same CDS sequence)	NM_020980.4 , NM_020980.3 , NM_020980.5
Accession Version	NM_020980.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	aquaporin-9
Comment

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAGTGGT GGCCACCATG ATACTCCTCA TAATCGTCTT TGCCATCTTT 
GACTCCAGAA ACTTGGGAGC CCCCAGAGGC CTAGAGCCCA TTGCCATCGG CCTCCTGATT 
ATTGTCATTG CTTCCTCCCT GGGACTGAAC AGTGGCTGTG CCATGAACCC AGCTCGAGAC 
CTGAGTCCCA GACTTTTCAC TGCCTTGGCA GGCTGGGGGT TTGAAGTCTT CAGAGCTGGA 
AACAACTTCT GGTGGATTCC TGTAGTGGGC CCTTTGGTTG GTGCTGTCAT TGGAGGCCTC 
ATCTATGTTC TTGTCATTGA AATCCACCAT CCAGAGCCTG ACTCAGTCTT TAAGACAGAA 
CAATCTGAGG ACAAACCAGA GAAATATGAA CTCAGTGTCA TCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066190.2
Translation	MQPEGAEKGKSFKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGAVIGGLIYVLVIEIHHPEPDSVFKTEQSEDKPEKYELSVIM

Target ORF information:

RefSeq Version	NM_020980.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens aquaporin 9 (AQP9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020980.3

ORF Insert Sequence:

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAGTGGT GGCCACCATG ATACTCCTCA TAATCGTCTT TGCCATCTTT 
GACTCCAGAA ACTTGGGAGC CCCCAGAGGC CTAGAGCCCA TTGCCATCGG CCTCCTGATT 
ATTGTCATTG CTTCCTCCCT GGGACTGAAC AGTGGCTGTG CCATGAACCC AGCTCGAGAC 
CTGAGTCCCA GACTTTTCAC TGCCTTGGCA GGCTGGGGGT TTGAAGTCTT CAGAGCTGGA 
AACAACTTCT GGTGGATTCC TGTAGTGGGC CCTTTGGTTG GTGCTGTCAT TGGAGGCCTC 
ATCTATGTTC TTGTCATTGA AATCCACCAT CCAGAGCCTG ACTCAGTCTT TAAGACAGAA 
CAATCTGAGG ACAAACCAGA GAAATATGAA CTCAGTGTCA TCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AQP9 ( NM_020980.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_066190.2 Homo sapiens aquaporin 9 (AQP9), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18497
Clone ID Related Accession (Same CDS sequence)	NM_020980.4 , NM_020980.3 , NM_020980.5
Accession Version	NM_020980.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	aquaporin-9 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB008775.1 and AC066616.7. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_020980.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138522.1295416.1, SRR1803612.80663.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000219919.9/ ENSP00000219919.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAGTGGT GGCCACCATG ATACTCCTCA TAATCGTCTT TGCCATCTTT 
GACTCCAGAA ACTTGGGAGC CCCCAGAGGC CTAGAGCCCA TTGCCATCGG CCTCCTGATT 
ATTGTCATTG CTTCCTCCCT GGGACTGAAC AGTGGCTGTG CCATGAACCC AGCTCGAGAC 
CTGAGTCCCA GACTTTTCAC TGCCTTGGCA GGCTGGGGGT TTGAAGTCTT CAGAGCTGGA 
AACAACTTCT GGTGGATTCC TGTAGTGGGC CCTTTGGTTG GTGCTGTCAT TGGAGGCCTC 
ATCTATGTTC TTGTCATTGA AATCCACCAT CCAGAGCCTG ACTCAGTCTT TAAGACAGAA 
CAATCTGAGG ACAAACCAGA GAAATATGAA CTCAGTGTCA TCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066190.2
CDS	186..1073
Translation	MQPEGAEKGKSFKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGAVIGGLIYVLVIEIHHPEPDSVFKTEQSEDKPEKYELSVIM

Target ORF information:

RefSeq Version	NM_020980.5
Organism	Homo sapiens(human)
Definition	Homo sapiens aquaporin 9 (AQP9), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020980.5

ORF Insert Sequence:

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAGTGGT GGCCACCATG ATACTCCTCA TAATCGTCTT TGCCATCTTT 
GACTCCAGAA ACTTGGGAGC CCCCAGAGGC CTAGAGCCCA TTGCCATCGG CCTCCTGATT 
ATTGTCATTG CTTCCTCCCT GGGACTGAAC AGTGGCTGTG CCATGAACCC AGCTCGAGAC 
CTGAGTCCCA GACTTTTCAC TGCCTTGGCA GGCTGGGGGT TTGAAGTCTT CAGAGCTGGA 
AACAACTTCT GGTGGATTCC TGTAGTGGGC CCTTTGGTTG GTGCTGTCAT TGGAGGCCTC 
ATCTATGTTC TTGTCATTGA AATCCACCAT CCAGAGCCTG ACTCAGTCTT TAAGACAGAA 
CAATCTGAGG ACAAACCAGA GAAATATGAA CTCAGTGTCA TCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AQP9 ( NM_001320636.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307565.1 Homo sapiens aquaporin 9 (AQP9), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu101942
Clone ID Related Accession (Same CDS sequence)	NM_001320636.1
Accession Version	NM_001320636.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	aquaporin-9 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC296768.1 and AC066616.7. Transcript Variant: This variant (3) uses an alternate 5' most exon which results in a distinct 5' UTR and the use of a downstream start codon compared to variant 1. The encoded isoform (3) has a shorter N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.20342.1, AK300055.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGTTG CAATGGCCAT TTATGTGGCT GGCGGTGTCT CTGGTGGTCA CATCAACCCA 
GCTGTGTCTT TAGCAATGTG TCTCTTTGGA CGGATGAAAT GGTTCAAATT GCCATTTTAT 
GTGGGAGCCC AGTTCTTGGG AGCCTTTGTG GGGGCTGCAA CCGTCTTTGG CATTTACTAT 
GATGGACTTA TGTCCTTTGC TGGTGGAAAA CTGCTGATCG TGGGAGAAAA TGCAACAGCA 
CACATTTTTG CAACATACCC AGCTCCGTAT CTATCTCTGG CGAACGCATT TGCAGATCAA 
GTGGTGGCCA CCATGATACT CCTCATAATC GTCTTTGCCA TCTTTGACTC CAGAAACTTG 
GGAGCCCCCA GAGGCCTAGA GCCCATTGCC ATCGGCCTCC TGATTATTGT CATTGCTTCC 
TCCCTGGGAC TGAACAGTGG CTGTGCCATG AACCCAGCTC GAGACCTGAG TCCCAGACTT 
TTCACTGCCT TGGCAGGCTG GGGGTTTGAA GTCTTCAGAG CTGGAAACAA CTTCTGGTGG 
ATTCCTGTAG TGGGCCCTTT GGTTGGTGCT GTCATTGGAG GCCTCATCTA TGTTCTTGTC 
ATTGAAATCC ACCATCCAGA GCCTGACTCA GTCTTTAAGA CAGAACAATC TGAGGACAAA 
CCAGAGAAAT ATGAACTCAG TGTCATCATG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307565.1
CDS	198..890
Translation	MAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGAVIGGLIYVLVIEIHHPEPDSVFKTEQSEDKPEKYELSVIM

Target ORF information:

RefSeq Version	NM_001320636.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aquaporin 9 (AQP9), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001320636.1

ORF Insert Sequence:

ATGGCAGTTG CAATGGCCAT TTATGTGGCT GGCGGTGTCT CTGGTGGTCA CATCAACCCA 
GCTGTGTCTT TAGCAATGTG TCTCTTTGGA CGGATGAAAT GGTTCAAATT GCCATTTTAT 
GTGGGAGCCC AGTTCTTGGG AGCCTTTGTG GGGGCTGCAA CCGTCTTTGG CATTTACTAT 
GATGGACTTA TGTCCTTTGC TGGTGGAAAA CTGCTGATCG TGGGAGAAAA TGCAACAGCA 
CACATTTTTG CAACATACCC AGCTCCGTAT CTATCTCTGG CGAACGCATT TGCAGATCAA 
GTGGTGGCCA CCATGATACT CCTCATAATC GTCTTTGCCA TCTTTGACTC CAGAAACTTG 
GGAGCCCCCA GAGGCCTAGA GCCCATTGCC ATCGGCCTCC TGATTATTGT CATTGCTTCC 
TCCCTGGGAC TGAACAGTGG CTGTGCCATG AACCCAGCTC GAGACCTGAG TCCCAGACTT 
TTCACTGCCT TGGCAGGCTG GGGGTTTGAA GTCTTCAGAG CTGGAAACAA CTTCTGGTGG 
ATTCCTGTAG TGGGCCCTTT GGTTGGTGCT GTCATTGGAG GCCTCATCTA TGTTCTTGTC 
ATTGAAATCC ACCATCCAGA GCCTGACTCA GTCTTTAAGA CAGAACAATC TGAGGACAAA 
CCAGAGAAAT ATGAACTCAG TGTCATCATG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AQP9 ( NM_001320635.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307564.1 Homo sapiens aquaporin 9 (AQP9), transcript variant 2, mRNA.

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CloneID	OHu101686
Clone ID Related Accession (Same CDS sequence)	NM_001320635.1 , NM_001320635.2
Accession Version	NM_001320635.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	aquaporin-9 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025431.7 and AC066616.7. Transcript Variant: This variant (2) lacks an exon in the 3' codingregion which results in a frameshift compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.260224.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146982, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAAGCTG GAAACAACTT CTGGTGGATT CCTGTAGTGG GCCCTTTGGT 
TGGTGCTGTC ATTGGAGGCC TCATCTATGT TCTTGTCATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307564.1
CDS	371..952
Translation	MQPEGAEKGKSFKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQSWKQLLVDSCSGPFGWCCHWRPHLCSCH

Target ORF information:

RefSeq Version	NM_001320635.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aquaporin 9 (AQP9), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001320635.1

ORF Insert Sequence:

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAAGCTG GAAACAACTT CTGGTGGATT CCTGTAGTGG GCCCTTTGGT 
TGGTGCTGTC ATTGGAGGCC TCATCTATGT TCTTGTCATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AQP9 ( NM_001320635.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307564.1 Homo sapiens aquaporin 9 (AQP9), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu101686
Clone ID Related Accession (Same CDS sequence)	NM_001320635.1 , NM_001320635.2
Accession Version	NM_001320635.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-08
Organism	Homo sapiens(human)
Product	aquaporin-9 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025431.7 and AC066616.7. On Jun 1, 2019 this sequence version replaced NM_001320635.1. Transcript Variant: This variant (2) lacks an exon in the 3' codingregion which results in a frameshift compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.260224.1, DRR138517.2206.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146982, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAAGCTG GAAACAACTT CTGGTGGATT CCTGTAGTGG GCCCTTTGGT 
TGGTGCTGTC ATTGGAGGCC TCATCTATGT TCTTGTCATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307564.1
CDS	186..767
Translation	MQPEGAEKGKSFKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQSWKQLLVDSCSGPFGWCCHWRPHLCSCH

Target ORF information:

RefSeq Version	NM_001320635.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aquaporin 9 (AQP9), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001320635.2

ORF Insert Sequence:

ATGCAGCCTG AGGGAGCAGA AAAGGGAAAA AGCTTCAAGC AGAGACTGGT CTTGAAGAGC 
AGCTTAGCGA AAGAAACCCT CTCTGAGTTC TTGGGCACGT TCATCTTGAT TGTCCTTGGA 
TGTGGCTGTG TTGCCCAAGC TATTCTCAGT CGAGGACGTT TTGGAGGGGT CATCACTATC 
AATGTTGGAT TTTCAATGGC AGTTGCAATG GCCATTTATG TGGCTGGCGG TGTCTCTGGT 
GGTCACATCA ACCCAGCTGT GTCTTTAGCA ATGTGTCTCT TTGGACGGAT GAAATGGTTC 
AAATTGCCAT TTTATGTGGG AGCCCAGTTC TTGGGAGCCT TTGTGGGGGC TGCAACCGTC 
TTTGGCATTT ACTATGATGG ACTTATGTCC TTTGCTGGTG GAAAACTGCT GATCGTGGGA 
GAAAATGCAA CAGCACACAT TTTTGCAACA TACCCAGCTC CGTATCTATC TCTGGCGAAC 
GCATTTGCAG ATCAAAGCTG GAAACAACTT CTGGTGGATT CCTGTAGTGG GCCCTTTGGT 
TGGTGCTGTC ATTGGAGGCC TCATCTATGT TCTTGTCATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure.
International journal of molecular sciences19(1)(2018 Jan)
Han X,Huang Q,Liu L,Sha X,Hu B,Liu H

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AQP9 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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