IRF1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IRF1
Entrez Gene ID	3659
Full Name	interferon regulatory factor 1
Synonyms	IRF-1,MAR
General protein information	Preferred Names interferon regulatory factor 1 Names interferon regulatory factor 1 interferon regulatory factor 1 isoform +I9 interferon regulatory factor 1 isoform d78 interferon regulatory factor 1 isoform d9,10+ interferon regulatory factor 1 isoform delta4 interferon regulatory factor 1 isoform delta7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q31.1
Summary	The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [provided by RefSeq, Aug 2017].
Disorder MIM:	147575
Disorder Html:	Myelodysplastic syndrome, preleukemic (3); Myelogenous leukemia, acute (3); Gastric cancer, somatic, 613659 (3); Nonsmall cell lung cancer, somatic, 211980 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011543378.2	XP_011541680.1	interferon regulatory factor 1 isoform X1
XM_011543379.2	XP_011541681.1	interferon regulatory factor 1 isoform X1
NM_001354925.1	NP_001341854.1	interferon regulatory factor 1 isoform 3
NM_002198.3	NP_002189.1	interferon regulatory factor 1 isoform 1
NM_001354924.1	NP_001341853.1	interferon regulatory factor 1 isoform 2
NM_002198.2	NP_002189.1	interferon regulatory factor 1 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	IRF1	XP_001150404.2
Canis lupus familiaris (dog)	IRF1	XP_003639416.2
Bos taurus (cattle)	IRF1	NP_001178190.1
Mus musculus (house mouse)	Irf1	NP_001152868.1
Homo sapiens (human)	IRF1	NP_002189.1
Rattus norvegicus (Norway rat)	Irf1	NP_036723.1
Danio rerio (zebrafish)	irf1b	NP_991310.1
	IRF1	XP_001104294.1
Gallus gallus (chicken)	IRF1	NP_990746.1
Xenopus tropicalis (tropical clawed frog)	irf1	NP_001006695.1

Gene Ontology

The following IRF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IRF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27700	NM_002198.3 Latest version!	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu58473	NM_001354924.1 Latest version!	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu58473	XM_011543378.2 Latest version!	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu58474	XM_011543379.2 Latest version!	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu103013	NM_001354925.1 Latest version!	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu27700	NM_002198.2	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IRF1 ( NM_002198.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002189.1 Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27700
Clone ID Related Accession (Same CDS sequence)	NM_002198.3 , NM_002198.2
Accession Version	NM_002198.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	interferon regulatory factor 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314025.1, BC009483.2, AC116366.2 and AA402319.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_002198.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314025.1, SRR3476690.44046.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000245414.9/ ENSP00000245414.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCACTGT CGCCATGTGC TGTCAGCAGC ACTCTCCCCG ACTGGCACAT CCCAGTGGAA 
GTTGTGCCGG ACAGCACCAG TGATCTGTAC AACTTCCAGG TGTCACCCAT GCCCTCCACC 
TCTGAAGCTA CAACAGATGA GGATGAGGAA GGGAAATTAC CTGAGGACAT CATGAAGCTC 
TTGGAGCAGT CGGAGTGGCA GCCAACAAAC GTGGATGGGA AGGGGTACCT ACTCAATGAA 
CCTGGAGTCC AGCCCACCTC TGTCTATGGA GACTTTAGCT GTAAGGAGGA GCCAGAAATT 
GACAGCCCAG GGGGGGATAT TGGGCTGAGT CTACAGCGTG TCTTCACAGA TCTGAAGAAC 
ATGGATGCCA CCTGGCTGGA CAGCCTGCTG ACCCCAGTCC GGTTGCCCTC CATCCAGGCC 
ATTCCCTGTG CACCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002189.1
CDS	235..1212
Translation	MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP

Target ORF information:

RefSeq Version	NM_002198.3
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002198.3

ORF Insert Sequence:

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCACTGT CGCCATGTGC TGTCAGCAGC ACTCTCCCCG ACTGGCACAT CCCAGTGGAA 
GTTGTGCCGG ACAGCACCAG TGATCTGTAC AACTTCCAGG TGTCACCCAT GCCCTCCACC 
TCTGAAGCTA CAACAGATGA GGATGAGGAA GGGAAATTAC CTGAGGACAT CATGAAGCTC 
TTGGAGCAGT CGGAGTGGCA GCCAACAAAC GTGGATGGGA AGGGGTACCT ACTCAATGAA 
CCTGGAGTCC AGCCCACCTC TGTCTATGGA GACTTTAGCT GTAAGGAGGA GCCAGAAATT 
GACAGCCCAG GGGGGGATAT TGGGCTGAGT CTACAGCGTG TCTTCACAGA TCTGAAGAAC 
ATGGATGCCA CCTGGCTGGA CAGCCTGCTG ACCCCAGTCC GGTTGCCCTC CATCCAGGCC 
ATTCCCTGTG CACCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRF1 ( NM_002198.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002189.1 Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27700
Clone ID Related Accession (Same CDS sequence)	NM_002198.3 , NM_002198.2
Accession Version	NM_002198.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	interferon regulatory factor 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314025.1, BC009483.2, AC116366.2 and AA402319.1. This sequence is a reference standard in the RefSeqGene project. On Aug 13, 2008 this sequence version replaced NM_002198.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314025.1, BC009483.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCACTGT CGCCATGTGC TGTCAGCAGC ACTCTCCCCG ACTGGCACAT CCCAGTGGAA 
GTTGTGCCGG ACAGCACCAG TGATCTGTAC AACTTCCAGG TGTCACCCAT GCCCTCCACC 
TCTGAAGCTA CAACAGATGA GGATGAGGAA GGGAAATTAC CTGAGGACAT CATGAAGCTC 
TTGGAGCAGT CGGAGTGGCA GCCAACAAAC GTGGATGGGA AGGGGTACCT ACTCAATGAA 
CCTGGAGTCC AGCCCACCTC TGTCTATGGA GACTTTAGCT GTAAGGAGGA GCCAGAAATT 
GACAGCCCAG GGGGGGATAT TGGGCTGAGT CTACAGCGTG TCTTCACAGA TCTGAAGAAC 
ATGGATGCCA CCTGGCTGGA CAGCCTGCTG ACCCCAGTCC GGTTGCCCTC CATCCAGGCC 
ATTCCCTGTG CACCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002189.1
CDS	235..1212
Translation	MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP

Target ORF information:

RefSeq Version	NM_002198.2
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002198.2

ORF Insert Sequence:

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCACTGT CGCCATGTGC TGTCAGCAGC ACTCTCCCCG ACTGGCACAT CCCAGTGGAA 
GTTGTGCCGG ACAGCACCAG TGATCTGTAC AACTTCCAGG TGTCACCCAT GCCCTCCACC 
TCTGAAGCTA CAACAGATGA GGATGAGGAA GGGAAATTAC CTGAGGACAT CATGAAGCTC 
TTGGAGCAGT CGGAGTGGCA GCCAACAAAC GTGGATGGGA AGGGGTACCT ACTCAATGAA 
CCTGGAGTCC AGCCCACCTC TGTCTATGGA GACTTTAGCT GTAAGGAGGA GCCAGAAATT 
GACAGCCCAG GGGGGGATAT TGGGCTGAGT CTACAGCGTG TCTTCACAGA TCTGAAGAAC 
ATGGATGCCA CCTGGCTGGA CAGCCTGCTG ACCCCAGTCC GGTTGCCCTC CATCCAGGCC 
ATTCCCTGTG CACCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRF1 ( NM_001354924.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341853.1 Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu58473
Clone ID Related Accession (Same CDS sequence)	XM_011543378.2 , NM_001354924.1
Accession Version	NM_001354924.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	interferon regulatory factor 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC116366.2 and KJ200634.1. On Aug 29, 2017 this sequence version replaced XM_011543378.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KJ200634.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCTACAA CAGATGAGGA TGAGGAAGGG AAATTACCTG AGGACATCAT GAAGCTCTTG 
GAGCAGTCGG AGTGGCAGCC AACAAACGTG GATGGGAAGG GGTACCTACT CAATGAACCT 
GGAGTCCAGC CCACCTCTGT CTATGGAGAC TTTAGCTGTA AGGAGGAGCC AGAAATTGAC 
AGCCCAGGGG GGGATATTGG GCTGAGTCTA CAGCGTGTCT TCACAGATCT GAAGAACATG 
GATGCCACCT GGCTGGACAG CCTGCTGACC CCAGTCCGGT TGCCCTCCAT CCAGGCCATT 
CCCTGTGCAC CGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341853.1
CDS	235..1089
Translation	MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP

Target ORF information:

RefSeq Version	NM_001354924.1
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354924.1

ORF Insert Sequence:

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCTACAA CAGATGAGGA TGAGGAAGGG AAATTACCTG AGGACATCAT GAAGCTCTTG 
GAGCAGTCGG AGTGGCAGCC AACAAACGTG GATGGGAAGG GGTACCTACT CAATGAACCT 
GGAGTCCAGC CCACCTCTGT CTATGGAGAC TTTAGCTGTA AGGAGGAGCC AGAAATTGAC 
AGCCCAGGGG GGGATATTGG GCTGAGTCTA CAGCGTGTCT TCACAGATCT GAAGAACATG 
GATGCCACCT GGCTGGACAG CCTGCTGACC CCAGTCCGGT TGCCCTCCAT CCAGGCCATT 
CCCTGTGCAC CGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRF1 ( XM_011543378.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541680.1 Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58473
Clone ID Related Accession (Same CDS sequence)	XM_011543378.2 , NM_001354924.1
Accession Version	XM_011543378.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(Human)
Product	interferon regulatory factor 1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011543378.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCTACAA CAGATGAGGA TGAGGAAGGG AAATTACCTG AGGACATCAT GAAGCTCTTG 
GAGCAGTCGG AGTGGCAGCC AACAAACGTG GATGGGAAGG GGTACCTACT CAATGAACCT 
GGAGTCCAGC CCACCTCTGT CTATGGAGAC TTTAGCTGTA AGGAGGAGCC AGAAATTGAC 
AGCCCAGGGG GGGATATTGG GCTGAGTCTA CAGCGTGTCT TCACAGATCT GAAGAACATG 
GATGCCACCT GGCTGGACAG CCTGCTGACC CCAGTCCGGT TGCCCTCCAT CCAGGCCATT 
CCCTGTGCAC CGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541680.1
CDS	235..1089
Translation	MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP

Target ORF information:

RefSeq Version	XM_011543378.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011543378.2

ORF Insert Sequence:

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCTACAA CAGATGAGGA TGAGGAAGGG AAATTACCTG AGGACATCAT GAAGCTCTTG 
GAGCAGTCGG AGTGGCAGCC AACAAACGTG GATGGGAAGG GGTACCTACT CAATGAACCT 
GGAGTCCAGC CCACCTCTGT CTATGGAGAC TTTAGCTGTA AGGAGGAGCC AGAAATTGAC 
AGCCCAGGGG GGGATATTGG GCTGAGTCTA CAGCGTGTCT TCACAGATCT GAAGAACATG 
GATGCCACCT GGCTGGACAG CCTGCTGACC CCAGTCCGGT TGCCCTCCAT CCAGGCCATT 
CCCTGTGCAC CGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRF1 ( XM_011543379.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541681.1 Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant X1, mRNA.

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CloneID	OHu58474
Clone ID Related Accession (Same CDS sequence)	XM_011543379.2
Accession Version	XM_011543379.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	interferon regulatory factor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011543379.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTCCC TGCCAGATAT CGAGGAGGTG AAAGACCAGA GCAGGAACAA GGGCAGCTCA 
GCTGTGCGAG TGTACCGGAT GCTTCCACCT CTCACCAAGA ACCAGAGAAA AGAAAGAAAG 
TCGAAGTCCA GCCGAGATGC TAAGAGCAAG GCCAAGAGGA AGTCATGTGG GGATTCCAGC 
CCTGATACCT TCTCTGATGG ACTCAGCAGC TCCACTCTGC CTGATGACCA CAGCAGCTAC 
ACAGTTCCAG GCTACATGCA GGACTTGGAG GTGGAGCAGG CCCTGACTCC AGCACTGTCG 
CCATGTGCTG TCAGCAGCAC TCTCCCCGAC TGGCACATCC CAGTGGAAGT TGTGCCGGAC 
AGCACCAGTG ATCTGTACAA CTTCCAGGTG TCACCCATGC CCTCCACCTC TGAAGCTACA 
ACAGATGAGG ATGAGGAAGG GAAATTACCT GAGGACATCA TGAAGCTCTT GGAGCAGTCG 
GAGTGGCAGC CAACAAACGT GGATGGGAAG GGGTACCTAC TCAATGAACC TGGAGTCCAG 
CCCACCTCTG TCTATGGAGA CTTTAGCTGT AAGGAGGAGC CAGAAATTGA CAGCCCAGGG 
GGGGATATTG GGCTGAGTCT ACAGCGTGTC TTCACAGATC TGAAGAACAT GGATGCCACC 
TGGCTGGACA GCCTGCTGAC CCCAGTCCGG TTGCCCTCCA TCCAGGCCAT TCCCTGTGCA 
CCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541681.1
CDS	311..1036
Translation	MNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP

Target ORF information:

RefSeq Version	XM_011543379.2
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011543379.2

ORF Insert Sequence:

ATGAACTCCC TGCCAGATAT CGAGGAGGTG AAAGACCAGA GCAGGAACAA GGGCAGCTCA 
GCTGTGCGAG TGTACCGGAT GCTTCCACCT CTCACCAAGA ACCAGAGAAA AGAAAGAAAG 
TCGAAGTCCA GCCGAGATGC TAAGAGCAAG GCCAAGAGGA AGTCATGTGG GGATTCCAGC 
CCTGATACCT TCTCTGATGG ACTCAGCAGC TCCACTCTGC CTGATGACCA CAGCAGCTAC 
ACAGTTCCAG GCTACATGCA GGACTTGGAG GTGGAGCAGG CCCTGACTCC AGCACTGTCG 
CCATGTGCTG TCAGCAGCAC TCTCCCCGAC TGGCACATCC CAGTGGAAGT TGTGCCGGAC 
AGCACCAGTG ATCTGTACAA CTTCCAGGTG TCACCCATGC CCTCCACCTC TGAAGCTACA 
ACAGATGAGG ATGAGGAAGG GAAATTACCT GAGGACATCA TGAAGCTCTT GGAGCAGTCG 
GAGTGGCAGC CAACAAACGT GGATGGGAAG GGGTACCTAC TCAATGAACC TGGAGTCCAG 
CCCACCTCTG TCTATGGAGA CTTTAGCTGT AAGGAGGAGC CAGAAATTGA CAGCCCAGGG 
GGGGATATTG GGCTGAGTCT ACAGCGTGTC TTCACAGATC TGAAGAACAT GGATGCCACC 
TGGCTGGACA GCCTGCTGAC CCCAGTCCGG TTGCCCTCCA TCCAGGCCAT TCCCTGTGCA 
CCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IRF1 ( NM_001354925.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341854.1 Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 3, mRNA.

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CloneID	OHu103013
Clone ID Related Accession (Same CDS sequence)	NM_001354925.1
Accession Version	NM_001354925.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	interferon regulatory factor 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC116366.2 and CT004274.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CT004274.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCACTGT CGCCATGTGC TGTCAGCAGC ACTCTCCCCG ACTGGCACAT CCCAGTGGAA 
GTTGTGCCGG ACAGCACCAG TGATCTGTAC AACTTCCAGG TGTCACCCAT GCCCTCCACC 
TCTGAAGGGG ATATTGGGCT GAGTCTACAG CGTGTCTTCA CAGATCTGAA GAACATGGAT 
GCCACCTGGC TGGACAGCCT GCTGACCCCA GTCCGGTTGC CCTCCATCCA GGCCATTCCC 
TGTGCACCGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341854.1
CDS	235..1026
Translation	MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALTPALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP

Target ORF information:

RefSeq Version	NM_001354925.1
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon regulatory factor 1 (IRF1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354925.1

ORF Insert Sequence:

ATGCCCATCA CTCGGATGCG CATGAGACCC TGGCTAGAGA TGCAGATTAA TTCCAACCAA 
ATCCCGGGGC TCATCTGGAT TAATAAAGAG GAGATGATCT TCCAGATCCC ATGGAAGCAT 
GCTGCCAAGC ATGGCTGGGA CATCAACAAG GATGCCTGTT TGTTCCGGAG CTGGGCCATT 
CACACAGGCC GATACAAAGC AGGGGAAAAG GAGCCAGATC CCAAGACGTG GAAGGCCAAC 
TTTCGCTGTG CCATGAACTC CCTGCCAGAT ATCGAGGAGG TGAAAGACCA GAGCAGGAAC 
AAGGGCAGCT CAGCTGTGCG AGTGTACCGG ATGCTTCCAC CTCTCACCAA GAACCAGAGA 
AAAGAAAGAA AGTCGAAGTC CAGCCGAGAT GCTAAGAGCA AGGCCAAGAG GAAGTCATGT 
GGGGATTCCA GCCCTGATAC CTTCTCTGAT GGACTCAGCA GCTCCACTCT GCCTGATGAC 
CACAGCAGCT ACACAGTTCC AGGCTACATG CAGGACTTGG AGGTGGAGCA GGCCCTGACT 
CCAGCACTGT CGCCATGTGC TGTCAGCAGC ACTCTCCCCG ACTGGCACAT CCCAGTGGAA 
GTTGTGCCGG ACAGCACCAG TGATCTGTAC AACTTCCAGG TGTCACCCAT GCCCTCCACC 
TCTGAAGGGG ATATTGGGCT GAGTCTACAG CGTGTCTTCA CAGATCTGAA GAACATGGAT 
GCCACCTGGC TGGACAGCCT GCTGACCCCA GTCCGGTTGC CCTCCATCCA GGCCATTCCC 
TGTGCACCGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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IRF1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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