INPP5D cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	INPP5D
Entrez Gene ID	3635
Full Name	inositol polyphosphate-5-phosphatase D
Synonyms	SHIP,SHIP-1,SHIP1,SIP-145,hp51CN,p150Ship
General protein information	Preferred Names inositol polyphosphate-5-phosphatase D Names phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 SH2 domain-containing inositol 5'-phosphatase 1 inositol polyphosphate-5-phosphatase, 145kD inositol polyphosphate-5-phosphatase, 145kDa signaling inositol polyphosphate 5 phosphatase SIP-145 signaling inositol polyphosphate phosphatase SHIP II
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q37.1
Summary	This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014].
Disorder MIM:	601582

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017915.2	NP_001017915.1	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform a
NM_001017915.3	NP_001017915.1	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform a
NM_005541.5	NP_005532.2	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform b
NM_005541.4	NP_005532.2	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform b
XM_017004004.1	XP_016859493.1	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	INPP5D	XP_526066.2
Mus musculus (house mouse)	Inpp5d	NP_034696.2
Rattus norvegicus (Norway rat)	Inpp5d	NP_062184.1
Danio rerio (zebrafish)	inpp5d	XP_001923007.3
Homo sapiens (human)	INPP5D	NP_001017915.1
Canis lupus familiaris (dog)	INPP5D	XP_005635922.1
Xenopus tropicalis (tropical clawed frog)	inpp5d	XP_002933378.2
Bos taurus (cattle)	INPP5D	NP_001095352.1
Gallus gallus (chicken)	INPP5D	XP_004936991.1

Gene Ontology
Bibliography

Related articles in PubMed

Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory Fc?RIIB.
Stopforth RJ, Oldham RJ, Tutt AL, Duriez P, Chan HTC, Binkowski BF, Zimprich C, Li D, Hargreaves PG, Cong M, Reddy V, Leandro MJ, Cambridge G, Lux A, Nimmerjahn F, Cragg MS
Journal of immunology (Baltimore, Md. : 1950)(2018 Jan)

Analysis of SHIP1 expression and activity in Crohn's disease patients.
Somasundaram R, Fernandes S, Deuring JJ, de Haar C, Kuipers EJ, Vogelaar L, Middleton FA, van der Woude CJ, Peppelenbosch MP, Kerr WG, Fuhler GM
PloS one12(8)e0182308(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study shows that SHIP1 activity is decreased in adult Crohn's disease (CD) patients either through reduced intrinsic enxymatic activity or reduced protein expression, and propose that in addition to ATG16L1, SHIP1 may contribute to the risk conferred by the 2q37 CD risk locus.
Title: Analysis of SHIP1 expression and activity in Crohn's disease patients.

SHIP has a role in extracellular matrix accumulation via suppressing PI3K/Akt/CTGF signaling in diabetic kidney dise
Title: SHIP, a novel factor to ameliorate extracellular matrix accumulation via suppressing PI3K/Akt/CTGF signaling in diabetic kidney disease.

results indicate that FcgammaRIIB is not uniquely able to promote membrane recruitment of SHIP, but rather modulates its function via formation of distinct signaling complexes. Membrane recruitment of SHIP via Syk-dependent mechanisms may be an important factor modulating immunoreceptor signaling.
Title: Fc?RIIB-Independent Mechanisms Controlling Membrane Localization of the Inhibitory Phosphatase SHIP in Human B Cells.

JARID1B directly bound to PI3K/AKT signaling inhibitor SHIP1 gene promoter and decreased SHIP1 gene expression.
Title: Overexpression of JARID1B promotes differentiation via SHIP1/AKT signaling in human hypopharyngeal squamous cell carcinoma.

Loss of SHIP promotes lung inflammation and mammary tumor metastasis.
Title: SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice.

The following INPP5D gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INPP5D cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26500	NM_005541.5 Latest version!	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu89375	XM_017004004.1 Latest version!	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
OHu26538	NM_001017915.3 Latest version!	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$384.30 $549.00
View Old Accession Versions >>
OHu26538	NM_001017915.2	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$384.30 $549.00
OHu26500	NM_005541.4	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

INPP5D ( NM_005541.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005532.2 Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26500
Clone ID Related Accession (Same CDS sequence)	NM_005541.5 , NM_005541.4
Accession Version	NM_005541.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Homo sapiens(human)
Product	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AW503130.1, BC099920.1 and X98429.1. On May 31, 2019 this sequence version replaced NM_005541.4. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC099920.1, SRR1803612.8738.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCCCCT GCTGGAACCA TGGCAACATC ACCCGCTCCA AGGCGGAGGA GCTGCTTTCC 
AGGACAGGCA AGGACGGGAG CTTCCTCGTG CGTGCCAGCG AGTCCATCTC CCGGGCATAC 
GCGCTCTGCG TGCTGTATCG GAATTGCGTT TACACTTACA GAATTCTGCC CAATGAAGAT 
GATAAATTCA CTGTTCAGGC ATCCGAAGGC GTCTCCATGA GGTTCTTCAC CAAGCTGGAC 
CAGCTCATCG AGTTTTACAA GAAGGAAAAC ATGGGGCTGG TGACCCATCT GCAATACCCT 
GTGCCGCTGG AGGAAGAGGA CACAGGCGAC GACCCTGAGG AGGACACAGA AAGTGTCGTG 
TCTCCACCCG AGCTGCCCCC AAGAAACATC CCGCTGACTG CCAGCTCCTG TGAGGCCAAG 
GAGGTTCCTT TTTCAAACGA GAATCCCCGA GCGACCGAGA CCAGCCGGCC GAGCCTCTCC 
GAGACATTGT TCCAGCGACT GCAAAGCATG GACACCAGTG GGCTTCCAGA AGAGCATCTT 
AAGGCCATCC AAGATTATTT AAGCACTCAG CTCGCCCAGG ACTCTGAATT TGTGAAGACA 
GGGTCCAGCA GTCTTCCTCA CCTGAAGAAA CTGACCACAC TGCTCTGCAA GGAGCTCTAT 
GGAGAAGTCA TCCGGACCCT CCCATCCCTG GAGTCTCTGC AGAGGTTATT TGACCAGCAG 
CTCTCCCCGG GCCTCCGTCC ACGTCCTCAG GTTCCTGGTG AGGCCAATCC CATCAACATG 
GTGTCCAAGC TCAGCCAACT GACAAGCCTG TTGTCGTCCA TTGAAGACAA GGTCAAGGCC 
TTGCTGCACG AGGGTCCTGA GTCTCCGCAC CGGCCCTCCC TTATCCCTCC AGTCACCTTT 
GAGGTGAAGG CAGAGTCTCT GGGGATTCCT CAGAAAATGC AGCTCAAAGT CGACGTTGAG 
TCTGGGAAAC TGATCATTAA GAAGTCCAAG GATGGTTCTG AGGACAAGTT CTACAGCCAC 
AAGAAAATCC TGCAGCTCAT TAAGTCACAG AAATTTCTGA ATAAGTTGGT GATCTTGGTG 
GAAACAGAGA AGGAGAAGAT CCTGCGGAAG GAATATGTTT TTGCTGACTC CAAAAAGAGA 
GAAGGCTTCT GCCAGCTCCT GCAGCAGATG AAGAACAAGC ACTCAGAGCA GCCGGAGCCC 
GACATGATCA CCATCTTCAT CGGCACCTGG AACATGGGTA ACGCCCCCCC TCCCAAGAAG 
ATCACGTCCT GGTTTCTCTC CAAGGGGCAG GGAAAGACGC GGGACGACTC TGCGGACTAC 
ATCCCCCATG ACATTTACGT GATCGGCACC CAAGAGGACC CCCTGAGTGA GAAGGAGTGG 
CTGGAGATCC TCAAACACTC CCTGCAAGAA ATCACCAGTG TGACTTTTAA AACAGTCGCC 
ATCCACACGC TCTGGAACAT CCGCATCGTG GTGCTGGCCA AGCCTGAGCA CGAGAACCGG 
ATCAGCCACA TCTGTACTGA CAACGTGAAG ACAGGCATTG CAAACACACT GGGGAACAAG 
GGAGCCGTGG GGGTGTCGTT CATGTTCAAT GGAACCTCCT TAGGGTTCGT CAACAGCCAC 
TTGACTTCAG GAAGTGAAAA GAAACTCAGG CGAAACCAAA ACTATATGAA CATTCTCCGG 
TTCCTGGCCC TGGGCGACAA GAAGCTGAGT CCCTTTAACA TCACTCACCG CTTCACGCAC 
CTCTTCTGGT TTGGGGATCT TAACTACCGT GTGGATCTGC CTACCTGGGA GGCAGAAACC 
ATCATCCAGA AAATCAAGCA GCAGCAGTAC GCAGACCTCC TGTCCCACGA CCAGCTGCTC 
ACAGAGAGGA GGGAGCAGAA GGTCTTCCTA CACTTCGAGG AGGAAGAAAT CACGTTTGCC 
CCAACCTACC GTTTTGAGAG ACTGACTCGG GACAAATACG CCTACACCAA GCAGAAAGCG 
ACAGGGATGA AGTACAACTT GCCTTCCTGG TGTGACCGAG TCCTCTGGAA GTCTTATCCC 
CTGGTGCACG TGGTGTGTCA GTCTTATGGC AGTACCAGCG ACATCATGAC GAGTGACCAC 
AGCCCTGTCT TTGCCACATT TGAGGCAGGA GTCACTTCCC AGTTTGTCTC CAAGAACGGT 
CCCGGGACTG TTGACAGCCA AGGACAGATT GAGTTTCTCA GGTGCTATGC CACATTGAAG 
ACCAAGTCCC AGACCAAATT CTACCTGGAG TTCCACTCGA GCTGCTTGGA GAGTTTTGTC 
AAGAGTCAGG AAGGAGAAAA TGAAGAAGGA AGTGAGGGGG AGCTGGTGGT GAAGTTTGGT 
GAGACTCTTC CAAAGCTGAA GCCCATTATC TCTGACCCTG AGTACCTGCT AGACCAGCAC 
ATCCTCATCA GCATCAAGTC CTCTGACAGC GACGAATCCT ATGGCGAGGG CTGCATTGCC 
CTTCGGTTAG AGGCCACAGA AACGCAGCTG CCCATCTACA CGCCTCTCAC CCACCATGGG 
GAGTTGACAG GCCACTTCCA GGGGGAGATC AAGCTGCAGA CCTCTCAGGG CAAGACGAGG 
GAGAAGCTCT ATGACTTTGT GAAGACGGAG CGTGATGAAT CCAGTGGGCC AAAGACCCTG 
AAGAGCCTCA CCAGCCACGA CCCCATGAAG CAGTGGGAAG TCACTAGCAG GGCCCCTCCG 
TGCAGTGGCT CCAGCATCAC TGAAATCATC AACCCCAACT ACATGGGAGT GGGGCCCTTT 
GGGCCACCAA TGCCCCTGCA CGTGAAGCAG ACCTTGTCCC CTGACCAGCA GCCCACAGCC 
TGGAGCTACG ACCAGCCGCC CAAGGACTCC CCGCTGGGGC CCTGCAGGGG AGAAAGTCCT 
CCGACACCTC CCGGCCAGCC GCCCATATCA CCCAAGAAGT TTTTACCCTC AACAGCAAAC 
CGGGGTCTCC CTCCCAGGAC ACAGGAGTCA AGGCCCAGTG ACCTGGGGAA GAACGCAGGG 
GACACGCTGC CTCAGGAGGA CCTGCCGCTG ACGAAGCCCG AGATGTTTGA GAACCCCCTG 
TATGGGTCCC TGAGTTCCTT CCCTAAGCCT GCTCCCAGGA AGGACCAGGA ATCCCCCAAA 
ATGCCGCGGA AGGAACCCCC GCCCTGCCCG GAACCCGGCA TCTTGTCGCC CAGCATCGTG 
CTCACCAAAG CCCAGGAGGC TGATCGCGGC GAGGGGCCCG GCAAGCAGGT GCCCGCGCCC 
CGGCTGCGCT CCTTCACGTG CTCATCCTCT GCCGAGGGCA GGGCGGCCGG CGGGGACAAG 
AGCCAAGGGA AGCCCAAGAC CCCGGTCAGC TCCCAGGCCC CGGTGCCGGC CAAGAGGCCC 
ATCAAGCCTT CCAGATCGGA AATCAACCAG CAGACCCCGC CCACCCCGAC GCCGCGGCCG 
CCGCTGCCAG TCAAGAGCCC GGCGGTGCTG CACCTCCAGC ACTCCAAGGG CCGCGACTAC 
CGCGACAACA CCGAGCTCCC GCATCACGGC AAGCACCGGC CGGAGGAGGG GCCACCAGGG 
CCTCTAGGCA GGACTGCCAT GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005532.2
CDS	138..3704
Translation	MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTESVVSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQLSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTFEVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ

Target ORF information:

RefSeq Version	NM_005541.5
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005541.5

ORF Insert Sequence:

ATGGTCCCCT GCTGGAACCA TGGCAACATC ACCCGCTCCA AGGCGGAGGA GCTGCTTTCC 
AGGACAGGCA AGGACGGGAG CTTCCTCGTG CGTGCCAGCG AGTCCATCTC CCGGGCATAC 
GCGCTCTGCG TGCTGTATCG GAATTGCGTT TACACTTACA GAATTCTGCC CAATGAAGAT 
GATAAATTCA CTGTTCAGGC ATCCGAAGGC GTCTCCATGA GGTTCTTCAC CAAGCTGGAC 
CAGCTCATCG AGTTTTACAA GAAGGAAAAC ATGGGGCTGG TGACCCATCT GCAATACCCT 
GTGCCGCTGG AGGAAGAGGA CACAGGCGAC GACCCTGAGG AGGACACAGA AAGTGTCGTG 
TCTCCACCCG AGCTGCCCCC AAGAAACATC CCGCTGACTG CCAGCTCCTG TGAGGCCAAG 
GAGGTTCCTT TTTCAAACGA GAATCCCCGA GCGACCGAGA CCAGCCGGCC GAGCCTCTCC 
GAGACATTGT TCCAGCGACT GCAAAGCATG GACACCAGTG GGCTTCCAGA AGAGCATCTT 
AAGGCCATCC AAGATTATTT AAGCACTCAG CTCGCCCAGG ACTCTGAATT TGTGAAGACA 
GGGTCCAGCA GTCTTCCTCA CCTGAAGAAA CTGACCACAC TGCTCTGCAA GGAGCTCTAT 
GGAGAAGTCA TCCGGACCCT CCCATCCCTG GAGTCTCTGC AGAGGTTATT TGACCAGCAG 
CTCTCCCCGG GCCTCCGTCC ACGTCCTCAG GTTCCTGGTG AGGCCAATCC CATCAACATG 
GTGTCCAAGC TCAGCCAACT GACAAGCCTG TTGTCGTCCA TTGAAGACAA GGTCAAGGCC 
TTGCTGCACG AGGGTCCTGA GTCTCCGCAC CGGCCCTCCC TTATCCCTCC AGTCACCTTT 
GAGGTGAAGG CAGAGTCTCT GGGGATTCCT CAGAAAATGC AGCTCAAAGT CGACGTTGAG 
TCTGGGAAAC TGATCATTAA GAAGTCCAAG GATGGTTCTG AGGACAAGTT CTACAGCCAC 
AAGAAAATCC TGCAGCTCAT TAAGTCACAG AAATTTCTGA ATAAGTTGGT GATCTTGGTG 
GAAACAGAGA AGGAGAAGAT CCTGCGGAAG GAATATGTTT TTGCTGACTC CAAAAAGAGA 
GAAGGCTTCT GCCAGCTCCT GCAGCAGATG AAGAACAAGC ACTCAGAGCA GCCGGAGCCC 
GACATGATCA CCATCTTCAT CGGCACCTGG AACATGGGTA ACGCCCCCCC TCCCAAGAAG 
ATCACGTCCT GGTTTCTCTC CAAGGGGCAG GGAAAGACGC GGGACGACTC TGCGGACTAC 
ATCCCCCATG ACATTTACGT GATCGGCACC CAAGAGGACC CCCTGAGTGA GAAGGAGTGG 
CTGGAGATCC TCAAACACTC CCTGCAAGAA ATCACCAGTG TGACTTTTAA AACAGTCGCC 
ATCCACACGC TCTGGAACAT CCGCATCGTG GTGCTGGCCA AGCCTGAGCA CGAGAACCGG 
ATCAGCCACA TCTGTACTGA CAACGTGAAG ACAGGCATTG CAAACACACT GGGGAACAAG 
GGAGCCGTGG GGGTGTCGTT CATGTTCAAT GGAACCTCCT TAGGGTTCGT CAACAGCCAC 
TTGACTTCAG GAAGTGAAAA GAAACTCAGG CGAAACCAAA ACTATATGAA CATTCTCCGG 
TTCCTGGCCC TGGGCGACAA GAAGCTGAGT CCCTTTAACA TCACTCACCG CTTCACGCAC 
CTCTTCTGGT TTGGGGATCT TAACTACCGT GTGGATCTGC CTACCTGGGA GGCAGAAACC 
ATCATCCAGA AAATCAAGCA GCAGCAGTAC GCAGACCTCC TGTCCCACGA CCAGCTGCTC 
ACAGAGAGGA GGGAGCAGAA GGTCTTCCTA CACTTCGAGG AGGAAGAAAT CACGTTTGCC 
CCAACCTACC GTTTTGAGAG ACTGACTCGG GACAAATACG CCTACACCAA GCAGAAAGCG 
ACAGGGATGA AGTACAACTT GCCTTCCTGG TGTGACCGAG TCCTCTGGAA GTCTTATCCC 
CTGGTGCACG TGGTGTGTCA GTCTTATGGC AGTACCAGCG ACATCATGAC GAGTGACCAC 
AGCCCTGTCT TTGCCACATT TGAGGCAGGA GTCACTTCCC AGTTTGTCTC CAAGAACGGT 
CCCGGGACTG TTGACAGCCA AGGACAGATT GAGTTTCTCA GGTGCTATGC CACATTGAAG 
ACCAAGTCCC AGACCAAATT CTACCTGGAG TTCCACTCGA GCTGCTTGGA GAGTTTTGTC 
AAGAGTCAGG AAGGAGAAAA TGAAGAAGGA AGTGAGGGGG AGCTGGTGGT GAAGTTTGGT 
GAGACTCTTC CAAAGCTGAA GCCCATTATC TCTGACCCTG AGTACCTGCT AGACCAGCAC 
ATCCTCATCA GCATCAAGTC CTCTGACAGC GACGAATCCT ATGGCGAGGG CTGCATTGCC 
CTTCGGTTAG AGGCCACAGA AACGCAGCTG CCCATCTACA CGCCTCTCAC CCACCATGGG 
GAGTTGACAG GCCACTTCCA GGGGGAGATC AAGCTGCAGA CCTCTCAGGG CAAGACGAGG 
GAGAAGCTCT ATGACTTTGT GAAGACGGAG CGTGATGAAT CCAGTGGGCC AAAGACCCTG 
AAGAGCCTCA CCAGCCACGA CCCCATGAAG CAGTGGGAAG TCACTAGCAG GGCCCCTCCG 
TGCAGTGGCT CCAGCATCAC TGAAATCATC AACCCCAACT ACATGGGAGT GGGGCCCTTT 
GGGCCACCAA TGCCCCTGCA CGTGAAGCAG ACCTTGTCCC CTGACCAGCA GCCCACAGCC 
TGGAGCTACG ACCAGCCGCC CAAGGACTCC CCGCTGGGGC CCTGCAGGGG AGAAAGTCCT 
CCGACACCTC CCGGCCAGCC GCCCATATCA CCCAAGAAGT TTTTACCCTC AACAGCAAAC 
CGGGGTCTCC CTCCCAGGAC ACAGGAGTCA AGGCCCAGTG ACCTGGGGAA GAACGCAGGG 
GACACGCTGC CTCAGGAGGA CCTGCCGCTG ACGAAGCCCG AGATGTTTGA GAACCCCCTG 
TATGGGTCCC TGAGTTCCTT CCCTAAGCCT GCTCCCAGGA AGGACCAGGA ATCCCCCAAA 
ATGCCGCGGA AGGAACCCCC GCCCTGCCCG GAACCCGGCA TCTTGTCGCC CAGCATCGTG 
CTCACCAAAG CCCAGGAGGC TGATCGCGGC GAGGGGCCCG GCAAGCAGGT GCCCGCGCCC 
CGGCTGCGCT CCTTCACGTG CTCATCCTCT GCCGAGGGCA GGGCGGCCGG CGGGGACAAG 
AGCCAAGGGA AGCCCAAGAC CCCGGTCAGC TCCCAGGCCC CGGTGCCGGC CAAGAGGCCC 
ATCAAGCCTT CCAGATCGGA AATCAACCAG CAGACCCCGC CCACCCCGAC GCCGCGGCCG 
CCGCTGCCAG TCAAGAGCCC GGCGGTGCTG CACCTCCAGC ACTCCAAGGG CCGCGACTAC 
CGCGACAACA CCGAGCTCCC GCATCACGGC AAGCACCGGC CGGAGGAGGG GCCACCAGGG 
CCTCTAGGCA GGACTGCCAT GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INPP5D ( NM_005541.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005532.2 Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26500
Clone ID Related Accession (Same CDS sequence)	NM_005541.5 , NM_005541.4
Accession Version	NM_005541.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U57650.1, AW503130.1, BC099920.1 and X98429.1. On Feb 19, 2014 this sequence version replaced NM_005541.3. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U57650.1, SRR1803612.8738.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCCCCT GCTGGAACCA TGGCAACATC ACCCGCTCCA AGGCGGAGGA GCTGCTTTCC 
AGGACAGGCA AGGACGGGAG CTTCCTCGTG CGTGCCAGCG AGTCCATCTC CCGGGCATAC 
GCGCTCTGCG TGCTGTATCG GAATTGCGTT TACACTTACA GAATTCTGCC CAATGAAGAT 
GATAAATTCA CTGTTCAGGC ATCCGAAGGC GTCTCCATGA GGTTCTTCAC CAAGCTGGAC 
CAGCTCATCG AGTTTTACAA GAAGGAAAAC ATGGGGCTGG TGACCCATCT GCAATACCCT 
GTGCCGCTGG AGGAAGAGGA CACAGGCGAC GACCCTGAGG AGGACACAGA AAGTGTCGTG 
TCTCCACCCG AGCTGCCCCC AAGAAACATC CCGCTGACTG CCAGCTCCTG TGAGGCCAAG 
GAGGTTCCTT TTTCAAACGA GAATCCCCGA GCGACCGAGA CCAGCCGGCC GAGCCTCTCC 
GAGACATTGT TCCAGCGACT GCAAAGCATG GACACCAGTG GGCTTCCAGA AGAGCATCTT 
AAGGCCATCC AAGATTATTT AAGCACTCAG CTCGCCCAGG ACTCTGAATT TGTGAAGACA 
GGGTCCAGCA GTCTTCCTCA CCTGAAGAAA CTGACCACAC TGCTCTGCAA GGAGCTCTAT 
GGAGAAGTCA TCCGGACCCT CCCATCCCTG GAGTCTCTGC AGAGGTTATT TGACCAGCAG 
CTCTCCCCGG GCCTCCGTCC ACGTCCTCAG GTTCCTGGTG AGGCCAATCC CATCAACATG 
GTGTCCAAGC TCAGCCAACT GACAAGCCTG TTGTCGTCCA TTGAAGACAA GGTCAAGGCC 
TTGCTGCACG AGGGTCCTGA GTCTCCGCAC CGGCCCTCCC TTATCCCTCC AGTCACCTTT 
GAGGTGAAGG CAGAGTCTCT GGGGATTCCT CAGAAAATGC AGCTCAAAGT CGACGTTGAG 
TCTGGGAAAC TGATCATTAA GAAGTCCAAG GATGGTTCTG AGGACAAGTT CTACAGCCAC 
AAGAAAATCC TGCAGCTCAT TAAGTCACAG AAATTTCTGA ATAAGTTGGT GATCTTGGTG 
GAAACAGAGA AGGAGAAGAT CCTGCGGAAG GAATATGTTT TTGCTGACTC CAAAAAGAGA 
GAAGGCTTCT GCCAGCTCCT GCAGCAGATG AAGAACAAGC ACTCAGAGCA GCCGGAGCCC 
GACATGATCA CCATCTTCAT CGGCACCTGG AACATGGGTA ACGCCCCCCC TCCCAAGAAG 
ATCACGTCCT GGTTTCTCTC CAAGGGGCAG GGAAAGACGC GGGACGACTC TGCGGACTAC 
ATCCCCCATG ACATTTACGT GATCGGCACC CAAGAGGACC CCCTGAGTGA GAAGGAGTGG 
CTGGAGATCC TCAAACACTC CCTGCAAGAA ATCACCAGTG TGACTTTTAA AACAGTCGCC 
ATCCACACGC TCTGGAACAT CCGCATCGTG GTGCTGGCCA AGCCTGAGCA CGAGAACCGG 
ATCAGCCACA TCTGTACTGA CAACGTGAAG ACAGGCATTG CAAACACACT GGGGAACAAG 
GGAGCCGTGG GGGTGTCGTT CATGTTCAAT GGAACCTCCT TAGGGTTCGT CAACAGCCAC 
TTGACTTCAG GAAGTGAAAA GAAACTCAGG CGAAACCAAA ACTATATGAA CATTCTCCGG 
TTCCTGGCCC TGGGCGACAA GAAGCTGAGT CCCTTTAACA TCACTCACCG CTTCACGCAC 
CTCTTCTGGT TTGGGGATCT TAACTACCGT GTGGATCTGC CTACCTGGGA GGCAGAAACC 
ATCATCCAGA AAATCAAGCA GCAGCAGTAC GCAGACCTCC TGTCCCACGA CCAGCTGCTC 
ACAGAGAGGA GGGAGCAGAA GGTCTTCCTA CACTTCGAGG AGGAAGAAAT CACGTTTGCC 
CCAACCTACC GTTTTGAGAG ACTGACTCGG GACAAATACG CCTACACCAA GCAGAAAGCG 
ACAGGGATGA AGTACAACTT GCCTTCCTGG TGTGACCGAG TCCTCTGGAA GTCTTATCCC 
CTGGTGCACG TGGTGTGTCA GTCTTATGGC AGTACCAGCG ACATCATGAC GAGTGACCAC 
AGCCCTGTCT TTGCCACATT TGAGGCAGGA GTCACTTCCC AGTTTGTCTC CAAGAACGGT 
CCCGGGACTG TTGACAGCCA AGGACAGATT GAGTTTCTCA GGTGCTATGC CACATTGAAG 
ACCAAGTCCC AGACCAAATT CTACCTGGAG TTCCACTCGA GCTGCTTGGA GAGTTTTGTC 
AAGAGTCAGG AAGGAGAAAA TGAAGAAGGA AGTGAGGGGG AGCTGGTGGT GAAGTTTGGT 
GAGACTCTTC CAAAGCTGAA GCCCATTATC TCTGACCCTG AGTACCTGCT AGACCAGCAC 
ATCCTCATCA GCATCAAGTC CTCTGACAGC GACGAATCCT ATGGCGAGGG CTGCATTGCC 
CTTCGGTTAG AGGCCACAGA AACGCAGCTG CCCATCTACA CGCCTCTCAC CCACCATGGG 
GAGTTGACAG GCCACTTCCA GGGGGAGATC AAGCTGCAGA CCTCTCAGGG CAAGACGAGG 
GAGAAGCTCT ATGACTTTGT GAAGACGGAG CGTGATGAAT CCAGTGGGCC AAAGACCCTG 
AAGAGCCTCA CCAGCCACGA CCCCATGAAG CAGTGGGAAG TCACTAGCAG GGCCCCTCCG 
TGCAGTGGCT CCAGCATCAC TGAAATCATC AACCCCAACT ACATGGGAGT GGGGCCCTTT 
GGGCCACCAA TGCCCCTGCA CGTGAAGCAG ACCTTGTCCC CTGACCAGCA GCCCACAGCC 
TGGAGCTACG ACCAGCCGCC CAAGGACTCC CCGCTGGGGC CCTGCAGGGG AGAAAGTCCT 
CCGACACCTC CCGGCCAGCC GCCCATATCA CCCAAGAAGT TTTTACCCTC AACAGCAAAC 
CGGGGTCTCC CTCCCAGGAC ACAGGAGTCA AGGCCCAGTG ACCTGGGGAA GAACGCAGGG 
GACACGCTGC CTCAGGAGGA CCTGCCGCTG ACGAAGCCCG AGATGTTTGA GAACCCCCTG 
TATGGGTCCC TGAGTTCCTT CCCTAAGCCT GCTCCCAGGA AGGACCAGGA ATCCCCCAAA 
ATGCCGCGGA AGGAACCCCC GCCCTGCCCG GAACCCGGCA TCTTGTCGCC CAGCATCGTG 
CTCACCAAAG CCCAGGAGGC TGATCGCGGC GAGGGGCCCG GCAAGCAGGT GCCCGCGCCC 
CGGCTGCGCT CCTTCACGTG CTCATCCTCT GCCGAGGGCA GGGCGGCCGG CGGGGACAAG 
AGCCAAGGGA AGCCCAAGAC CCCGGTCAGC TCCCAGGCCC CGGTGCCGGC CAAGAGGCCC 
ATCAAGCCTT CCAGATCGGA AATCAACCAG CAGACCCCGC CCACCCCGAC GCCGCGGCCG 
CCGCTGCCAG TCAAGAGCCC GGCGGTGCTG CACCTCCAGC ACTCCAAGGG CCGCGACTAC 
CGCGACAACA CCGAGCTCCC GCATCACGGC AAGCACCGGC CGGAGGAGGG GCCACCAGGG 
CCTCTAGGCA GGACTGCCAT GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005532.2
CDS	513..4079
Translation	MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTESVVSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQLSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTFEVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ

Target ORF information:

RefSeq Version	NM_005541.4
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005541.4

ORF Insert Sequence:

ATGGTCCCCT GCTGGAACCA TGGCAACATC ACCCGCTCCA AGGCGGAGGA GCTGCTTTCC 
AGGACAGGCA AGGACGGGAG CTTCCTCGTG CGTGCCAGCG AGTCCATCTC CCGGGCATAC 
GCGCTCTGCG TGCTGTATCG GAATTGCGTT TACACTTACA GAATTCTGCC CAATGAAGAT 
GATAAATTCA CTGTTCAGGC ATCCGAAGGC GTCTCCATGA GGTTCTTCAC CAAGCTGGAC 
CAGCTCATCG AGTTTTACAA GAAGGAAAAC ATGGGGCTGG TGACCCATCT GCAATACCCT 
GTGCCGCTGG AGGAAGAGGA CACAGGCGAC GACCCTGAGG AGGACACAGA AAGTGTCGTG 
TCTCCACCCG AGCTGCCCCC AAGAAACATC CCGCTGACTG CCAGCTCCTG TGAGGCCAAG 
GAGGTTCCTT TTTCAAACGA GAATCCCCGA GCGACCGAGA CCAGCCGGCC GAGCCTCTCC 
GAGACATTGT TCCAGCGACT GCAAAGCATG GACACCAGTG GGCTTCCAGA AGAGCATCTT 
AAGGCCATCC AAGATTATTT AAGCACTCAG CTCGCCCAGG ACTCTGAATT TGTGAAGACA 
GGGTCCAGCA GTCTTCCTCA CCTGAAGAAA CTGACCACAC TGCTCTGCAA GGAGCTCTAT 
GGAGAAGTCA TCCGGACCCT CCCATCCCTG GAGTCTCTGC AGAGGTTATT TGACCAGCAG 
CTCTCCCCGG GCCTCCGTCC ACGTCCTCAG GTTCCTGGTG AGGCCAATCC CATCAACATG 
GTGTCCAAGC TCAGCCAACT GACAAGCCTG TTGTCGTCCA TTGAAGACAA GGTCAAGGCC 
TTGCTGCACG AGGGTCCTGA GTCTCCGCAC CGGCCCTCCC TTATCCCTCC AGTCACCTTT 
GAGGTGAAGG CAGAGTCTCT GGGGATTCCT CAGAAAATGC AGCTCAAAGT CGACGTTGAG 
TCTGGGAAAC TGATCATTAA GAAGTCCAAG GATGGTTCTG AGGACAAGTT CTACAGCCAC 
AAGAAAATCC TGCAGCTCAT TAAGTCACAG AAATTTCTGA ATAAGTTGGT GATCTTGGTG 
GAAACAGAGA AGGAGAAGAT CCTGCGGAAG GAATATGTTT TTGCTGACTC CAAAAAGAGA 
GAAGGCTTCT GCCAGCTCCT GCAGCAGATG AAGAACAAGC ACTCAGAGCA GCCGGAGCCC 
GACATGATCA CCATCTTCAT CGGCACCTGG AACATGGGTA ACGCCCCCCC TCCCAAGAAG 
ATCACGTCCT GGTTTCTCTC CAAGGGGCAG GGAAAGACGC GGGACGACTC TGCGGACTAC 
ATCCCCCATG ACATTTACGT GATCGGCACC CAAGAGGACC CCCTGAGTGA GAAGGAGTGG 
CTGGAGATCC TCAAACACTC CCTGCAAGAA ATCACCAGTG TGACTTTTAA AACAGTCGCC 
ATCCACACGC TCTGGAACAT CCGCATCGTG GTGCTGGCCA AGCCTGAGCA CGAGAACCGG 
ATCAGCCACA TCTGTACTGA CAACGTGAAG ACAGGCATTG CAAACACACT GGGGAACAAG 
GGAGCCGTGG GGGTGTCGTT CATGTTCAAT GGAACCTCCT TAGGGTTCGT CAACAGCCAC 
TTGACTTCAG GAAGTGAAAA GAAACTCAGG CGAAACCAAA ACTATATGAA CATTCTCCGG 
TTCCTGGCCC TGGGCGACAA GAAGCTGAGT CCCTTTAACA TCACTCACCG CTTCACGCAC 
CTCTTCTGGT TTGGGGATCT TAACTACCGT GTGGATCTGC CTACCTGGGA GGCAGAAACC 
ATCATCCAGA AAATCAAGCA GCAGCAGTAC GCAGACCTCC TGTCCCACGA CCAGCTGCTC 
ACAGAGAGGA GGGAGCAGAA GGTCTTCCTA CACTTCGAGG AGGAAGAAAT CACGTTTGCC 
CCAACCTACC GTTTTGAGAG ACTGACTCGG GACAAATACG CCTACACCAA GCAGAAAGCG 
ACAGGGATGA AGTACAACTT GCCTTCCTGG TGTGACCGAG TCCTCTGGAA GTCTTATCCC 
CTGGTGCACG TGGTGTGTCA GTCTTATGGC AGTACCAGCG ACATCATGAC GAGTGACCAC 
AGCCCTGTCT TTGCCACATT TGAGGCAGGA GTCACTTCCC AGTTTGTCTC CAAGAACGGT 
CCCGGGACTG TTGACAGCCA AGGACAGATT GAGTTTCTCA GGTGCTATGC CACATTGAAG 
ACCAAGTCCC AGACCAAATT CTACCTGGAG TTCCACTCGA GCTGCTTGGA GAGTTTTGTC 
AAGAGTCAGG AAGGAGAAAA TGAAGAAGGA AGTGAGGGGG AGCTGGTGGT GAAGTTTGGT 
GAGACTCTTC CAAAGCTGAA GCCCATTATC TCTGACCCTG AGTACCTGCT AGACCAGCAC 
ATCCTCATCA GCATCAAGTC CTCTGACAGC GACGAATCCT ATGGCGAGGG CTGCATTGCC 
CTTCGGTTAG AGGCCACAGA AACGCAGCTG CCCATCTACA CGCCTCTCAC CCACCATGGG 
GAGTTGACAG GCCACTTCCA GGGGGAGATC AAGCTGCAGA CCTCTCAGGG CAAGACGAGG 
GAGAAGCTCT ATGACTTTGT GAAGACGGAG CGTGATGAAT CCAGTGGGCC AAAGACCCTG 
AAGAGCCTCA CCAGCCACGA CCCCATGAAG CAGTGGGAAG TCACTAGCAG GGCCCCTCCG 
TGCAGTGGCT CCAGCATCAC TGAAATCATC AACCCCAACT ACATGGGAGT GGGGCCCTTT 
GGGCCACCAA TGCCCCTGCA CGTGAAGCAG ACCTTGTCCC CTGACCAGCA GCCCACAGCC 
TGGAGCTACG ACCAGCCGCC CAAGGACTCC CCGCTGGGGC CCTGCAGGGG AGAAAGTCCT 
CCGACACCTC CCGGCCAGCC GCCCATATCA CCCAAGAAGT TTTTACCCTC AACAGCAAAC 
CGGGGTCTCC CTCCCAGGAC ACAGGAGTCA AGGCCCAGTG ACCTGGGGAA GAACGCAGGG 
GACACGCTGC CTCAGGAGGA CCTGCCGCTG ACGAAGCCCG AGATGTTTGA GAACCCCCTG 
TATGGGTCCC TGAGTTCCTT CCCTAAGCCT GCTCCCAGGA AGGACCAGGA ATCCCCCAAA 
ATGCCGCGGA AGGAACCCCC GCCCTGCCCG GAACCCGGCA TCTTGTCGCC CAGCATCGTG 
CTCACCAAAG CCCAGGAGGC TGATCGCGGC GAGGGGCCCG GCAAGCAGGT GCCCGCGCCC 
CGGCTGCGCT CCTTCACGTG CTCATCCTCT GCCGAGGGCA GGGCGGCCGG CGGGGACAAG 
AGCCAAGGGA AGCCCAAGAC CCCGGTCAGC TCCCAGGCCC CGGTGCCGGC CAAGAGGCCC 
ATCAAGCCTT CCAGATCGGA AATCAACCAG CAGACCCCGC CCACCCCGAC GCCGCGGCCG 
CCGCTGCCAG TCAAGAGCCC GGCGGTGCTG CACCTCCAGC ACTCCAAGGG CCGCGACTAC 
CGCGACAACA CCGAGCTCCC GCATCACGGC AAGCACCGGC CGGAGGAGGG GCCACCAGGG 
CCTCTAGGCA GGACTGCCAT GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INPP5D ( XM_017004004.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859493.1 Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant X1, mRNA.

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CloneID	OHu89375
Clone ID Related Accession (Same CDS sequence)	XM_017004004.1
Accession Version	XM_017004004.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1986bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCAATG GAACCTCCTT AGGGTTCGTC AACAGCCACT TGACTTCAGG AAGTGAAAAG 
AAACTCAGGC GAAACCAAAA CTATATGAAC ATTCTCCGGT TCCTGGCCCT GGGCGACAAG 
AAGCTGAGTC CCTTTAACAT CACTCACCGC TTCACGCACC TCTTCTGGTT TGGGGATCTT 
AACTACCGTG TGGATCTGCC TACCTGGGAG GCAGAAACCA TCATCCAGAA AATCAAGCAG 
CAGCAGTACG CAGACCTCCT GTCCCACGAC CAGCTGCTCA CAGAGAGGAG GGAGCAGAAG 
GTCTTCCTAC ACTTCGAGGA GGAAGAAATC ACGTTTGCCC CAACCTACCG TTTTGAGAGA 
CTGACTCGGG ACAAATACGC CTACACCAAG CAGAAAGCGA CAGGGATGAA GTACAACTTG 
CCTTCCTGGT GTGACCGAGT CCTCTGGAAG TCTTATCCCC TGGTGCACGT GGTGTGTCAG 
TCTTATGGCA GTACCAGCGA CATCATGACG AGTGACCACA GCCCTGTCTT TGCCACATTT 
GAGGCAGGAG TCACTTCCCA GTTTGTCTCC AAGAACGGTC CCGGGACTGT TGACAGCCAA 
GGACAGATTG AGTTTCTCAG GTGCTATGCC ACATTGAAGA CCAAGTCCCA GACCAAATTC 
TACCTGGAGT TCCACTCGAG CTGCTTGGAG AGTTTTGTCA AGAGTCAGGA AGGAGAAAAT 
GAAGAAGGAA GTGAGGGGGA GCTGGTGGTG AAGTTTGGTG AGACTCTTCC AAAGCTGAAG 
CCCATTATCT CTGACCCTGA GTACCTGCTA GACCAGCACA TCCTCATCAG CATCAAGTCC 
TCTGACAGCG ACGAATCCTA TGGCGAGGGC TGCATTGCCC TTCGGTTAGA GGCCACAGAA 
ACGCAGCTGC CCATCTACAC GCCTCTCACC CACCATGGGG AGTTGACAGG CCACTTCCAG 
GGGGAGATCA AGCTGCAGAC CTCTCAGGGC AAGACGAGGG AGAAGCTCTA TGACTTTGTG 
AAGACGGAGC GTGATGAATC CAGTGGGCCA AAGACCCTGA AGAGCCTCAC CAGCCACGAC 
CCCATGAAGC AGTGGGAAGT CACTAGCAGG GCCCCTCCGT GCAGTGGCTC CAGCATCACT 
GAAATCATCA ACCCCAACTA CATGGGAGTG GGGCCCTTTG GGCCACCAAT GCCCCTGCAC 
GTGAAGCAGA CCTTGTCCCC TGACCAGCAG CCCACAGCCT GGAGCTACGA CCAGCCGCCC 
AAGGACTCCC CGCTGGGGCC CTGCAGGGGA GAAAGTCCTC CGACACCTCC CGGCCAGCCG 
CCCATATCAC CCAAGAAGTT TTTACCCTCA ACAGCAAACC GGGGTCTCCC TCCCAGGACA 
CAGGAGTCAA GGCCCAGTGA CCTGGGGAAG AACGCAGGGG ACACGCTGCC TCAGGAGGAC 
CTGCCGCTGA CGAAGCCCGA GATGTTTGAG AACCCCCTGT ATGGGTCCCT GAGTTCCTTC 
CCTAAGCCTG CTCCCAGGAA GGACCAGGAA TCCCCCAAAA TGCCGCGGAA GGAACCCCCG 
CCCTGCCCGG AACCCGGCAT CTTGTCGCCC AGCATCGTGC TCACCAAAGC CCAGGAGGCT 
GATCGCGGCG AGGGGCCCGG CAAGCAGGTG CCCGCGCCCC GGCTGCGCTC CTTCACGTGC 
TCATCCTCTG CCGAGGGCAG GGCGGCCGGC GGGGACAAGA GCCAAGGGAA GCCCAAGACC 
CCGGTCAGCT CCCAGGCCCC GGTGCCGGCC AAGAGGCCCA TCAAGCCTTC CAGATCGGAA 
ATCAACCAGC AGACCCCGCC CACCCCGACG CCGCGGCCGC CGCTGCCAGT CAAGAGCCCG 
GCGGTGCTGC ACCTCCAGCA CTCCAAGGGC CGCGACTACC GCGACAACAC CGAGCTCCCG 
CATCACGGCA AGCACCGGCC GGAGGAGGGG CCACCAGGGC CTCTAGGCAG GACTGCCATG 
CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859493.1
CDS	1673..3658
Translation	MFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ

Target ORF information:

RefSeq Version	XM_017004004.1
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017004004.1

ORF Insert Sequence:

ATGTTCAATG GAACCTCCTT AGGGTTCGTC AACAGCCACT TGACTTCAGG AAGTGAAAAG 
AAACTCAGGC GAAACCAAAA CTATATGAAC ATTCTCCGGT TCCTGGCCCT GGGCGACAAG 
AAGCTGAGTC CCTTTAACAT CACTCACCGC TTCACGCACC TCTTCTGGTT TGGGGATCTT 
AACTACCGTG TGGATCTGCC TACCTGGGAG GCAGAAACCA TCATCCAGAA AATCAAGCAG 
CAGCAGTACG CAGACCTCCT GTCCCACGAC CAGCTGCTCA CAGAGAGGAG GGAGCAGAAG 
GTCTTCCTAC ACTTCGAGGA GGAAGAAATC ACGTTTGCCC CAACCTACCG TTTTGAGAGA 
CTGACTCGGG ACAAATACGC CTACACCAAG CAGAAAGCGA CAGGGATGAA GTACAACTTG 
CCTTCCTGGT GTGACCGAGT CCTCTGGAAG TCTTATCCCC TGGTGCACGT GGTGTGTCAG 
TCTTATGGCA GTACCAGCGA CATCATGACG AGTGACCACA GCCCTGTCTT TGCCACATTT 
GAGGCAGGAG TCACTTCCCA GTTTGTCTCC AAGAACGGTC CCGGGACTGT TGACAGCCAA 
GGACAGATTG AGTTTCTCAG GTGCTATGCC ACATTGAAGA CCAAGTCCCA GACCAAATTC 
TACCTGGAGT TCCACTCGAG CTGCTTGGAG AGTTTTGTCA AGAGTCAGGA AGGAGAAAAT 
GAAGAAGGAA GTGAGGGGGA GCTGGTGGTG AAGTTTGGTG AGACTCTTCC AAAGCTGAAG 
CCCATTATCT CTGACCCTGA GTACCTGCTA GACCAGCACA TCCTCATCAG CATCAAGTCC 
TCTGACAGCG ACGAATCCTA TGGCGAGGGC TGCATTGCCC TTCGGTTAGA GGCCACAGAA 
ACGCAGCTGC CCATCTACAC GCCTCTCACC CACCATGGGG AGTTGACAGG CCACTTCCAG 
GGGGAGATCA AGCTGCAGAC CTCTCAGGGC AAGACGAGGG AGAAGCTCTA TGACTTTGTG 
AAGACGGAGC GTGATGAATC CAGTGGGCCA AAGACCCTGA AGAGCCTCAC CAGCCACGAC 
CCCATGAAGC AGTGGGAAGT CACTAGCAGG GCCCCTCCGT GCAGTGGCTC CAGCATCACT 
GAAATCATCA ACCCCAACTA CATGGGAGTG GGGCCCTTTG GGCCACCAAT GCCCCTGCAC 
GTGAAGCAGA CCTTGTCCCC TGACCAGCAG CCCACAGCCT GGAGCTACGA CCAGCCGCCC 
AAGGACTCCC CGCTGGGGCC CTGCAGGGGA GAAAGTCCTC CGACACCTCC CGGCCAGCCG 
CCCATATCAC CCAAGAAGTT TTTACCCTCA ACAGCAAACC GGGGTCTCCC TCCCAGGACA 
CAGGAGTCAA GGCCCAGTGA CCTGGGGAAG AACGCAGGGG ACACGCTGCC TCAGGAGGAC 
CTGCCGCTGA CGAAGCCCGA GATGTTTGAG AACCCCCTGT ATGGGTCCCT GAGTTCCTTC 
CCTAAGCCTG CTCCCAGGAA GGACCAGGAA TCCCCCAAAA TGCCGCGGAA GGAACCCCCG 
CCCTGCCCGG AACCCGGCAT CTTGTCGCCC AGCATCGTGC TCACCAAAGC CCAGGAGGCT 
GATCGCGGCG AGGGGCCCGG CAAGCAGGTG CCCGCGCCCC GGCTGCGCTC CTTCACGTGC 
TCATCCTCTG CCGAGGGCAG GGCGGCCGGC GGGGACAAGA GCCAAGGGAA GCCCAAGACC 
CCGGTCAGCT CCCAGGCCCC GGTGCCGGCC AAGAGGCCCA TCAAGCCTTC CAGATCGGAA 
ATCAACCAGC AGACCCCGCC CACCCCGACG CCGCGGCCGC CGCTGCCAGT CAAGAGCCCG 
GCGGTGCTGC ACCTCCAGCA CTCCAAGGGC CGCGACTACC GCGACAACAC CGAGCTCCCG 
CATCACGGCA AGCACCGGCC GGAGGAGGGG CCACCAGGGC CTCTAGGCAG GACTGCCATG 
CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INPP5D ( NM_001017915.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001017915.1 Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 1, mRNA.

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CloneID	OHu26538
Clone ID Related Accession (Same CDS sequence)	NM_001017915.2 , NM_001017915.3
Accession Version	NM_001017915.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-08
Organism	Homo sapiens(human)
Product	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U57650.1, AW503130.1, U53470.1 and BC099920.1. This sequence is a reference standard in the RefSeqGene project. On Feb 19, 2014 this sequence version replaced NM_001017915.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.38964.1, U84400.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCCCCT GCTGGAACCA TGGCAACATC ACCCGCTCCA AGGCGGAGGA GCTGCTTTCC 
AGGACAGGCA AGGACGGGAG CTTCCTCGTG CGTGCCAGCG AGTCCATCTC CCGGGCATAC 
GCGCTCTGCG TGCTGTATCG GAATTGCGTT TACACTTACA GAATTCTGCC CAATGAAGAT 
GATAAATTCA CTGTTCAGGC ATCCGAAGGC GTCTCCATGA GGTTCTTCAC CAAGCTGGAC 
CAGCTCATCG AGTTTTACAA GAAGGAAAAC ATGGGGCTGG TGACCCATCT GCAATACCCT 
GTGCCGCTGG AGGAAGAGGA CACAGGCGAC GACCCTGAGG AGGACACAGT AGAAAGTGTC 
GTGTCTCCAC CCGAGCTGCC CCCAAGAAAC ATCCCGCTGA CTGCCAGCTC CTGTGAGGCC 
AAGGAGGTTC CTTTTTCAAA CGAGAATCCC CGAGCGACCG AGACCAGCCG GCCGAGCCTC 
TCCGAGACAT TGTTCCAGCG ACTGCAAAGC ATGGACACCA GTGGGCTTCC AGAAGAGCAT 
CTTAAGGCCA TCCAAGATTA TTTAAGCACT CAGCTCGCCC AGGACTCTGA ATTTGTGAAG 
ACAGGGTCCA GCAGTCTTCC TCACCTGAAG AAACTGACCA CACTGCTCTG CAAGGAGCTC 
TATGGAGAAG TCATCCGGAC CCTCCCATCC CTGGAGTCTC TGCAGAGGTT ATTTGACCAG 
CAGCTCTCCC CGGGCCTCCG TCCACGTCCT CAGGTTCCTG GTGAGGCCAA TCCCATCAAC 
ATGGTGTCCA AGCTCAGCCA ACTGACAAGC CTGTTGTCGT CCATTGAAGA CAAGGTCAAG 
GCCTTGCTGC ACGAGGGTCC TGAGTCTCCG CACCGGCCCT CCCTTATCCC TCCAGTCACC 
TTTGAGGTGA AGGCAGAGTC TCTGGGGATT CCTCAGAAAA TGCAGCTCAA AGTCGACGTT 
GAGTCTGGGA AACTGATCAT TAAGAAGTCC AAGGATGGTT CTGAGGACAA GTTCTACAGC 
CACAAGAAAA TCCTGCAGCT CATTAAGTCA CAGAAATTTC TGAATAAGTT GGTGATCTTG 
GTGGAAACAG AGAAGGAGAA GATCCTGCGG AAGGAATATG TTTTTGCTGA CTCCAAAAAG 
AGAGAAGGCT TCTGCCAGCT CCTGCAGCAG ATGAAGAACA AGCACTCAGA GCAGCCGGAG 
CCCGACATGA TCACCATCTT CATCGGCACC TGGAACATGG GTAACGCCCC CCCTCCCAAG 
AAGATCACGT CCTGGTTTCT CTCCAAGGGG CAGGGAAAGA CGCGGGACGA CTCTGCGGAC 
TACATCCCCC ATGACATTTA CGTGATCGGC ACCCAAGAGG ACCCCCTGAG TGAGAAGGAG 
TGGCTGGAGA TCCTCAAACA CTCCCTGCAA GAAATCACCA GTGTGACTTT TAAAACAGTC 
GCCATCCACA CGCTCTGGAA CATCCGCATC GTGGTGCTGG CCAAGCCTGA GCACGAGAAC 
CGGATCAGCC ACATCTGTAC TGACAACGTG AAGACAGGCA TTGCAAACAC ACTGGGGAAC 
AAGGGAGCCG TGGGGGTGTC GTTCATGTTC AATGGAACCT CCTTAGGGTT CGTCAACAGC 
CACTTGACTT CAGGAAGTGA AAAGAAACTC AGGCGAAACC AAAACTATAT GAACATTCTC 
CGGTTCCTGG CCCTGGGCGA CAAGAAGCTG AGTCCCTTTA ACATCACTCA CCGCTTCACG 
CACCTCTTCT GGTTTGGGGA TCTTAACTAC CGTGTGGATC TGCCTACCTG GGAGGCAGAA 
ACCATCATCC AGAAAATCAA GCAGCAGCAG TACGCAGACC TCCTGTCCCA CGACCAGCTG 
CTCACAGAGA GGAGGGAGCA GAAGGTCTTC CTACACTTCG AGGAGGAAGA AATCACGTTT 
GCCCCAACCT ACCGTTTTGA GAGACTGACT CGGGACAAAT ACGCCTACAC CAAGCAGAAA 
GCGACAGGGA TGAAGTACAA CTTGCCTTCC TGGTGTGACC GAGTCCTCTG GAAGTCTTAT 
CCCCTGGTGC ACGTGGTGTG TCAGTCTTAT GGCAGTACCA GCGACATCAT GACGAGTGAC 
CACAGCCCTG TCTTTGCCAC ATTTGAGGCA GGAGTCACTT CCCAGTTTGT CTCCAAGAAC 
GGTCCCGGGA CTGTTGACAG CCAAGGACAG ATTGAGTTTC TCAGGTGCTA TGCCACATTG 
AAGACCAAGT CCCAGACCAA ATTCTACCTG GAGTTCCACT CGAGCTGCTT GGAGAGTTTT 
GTCAAGAGTC AGGAAGGAGA AAATGAAGAA GGAAGTGAGG GGGAGCTGGT GGTGAAGTTT 
GGTGAGACTC TTCCAAAGCT GAAGCCCATT ATCTCTGACC CTGAGTACCT GCTAGACCAG 
CACATCCTCA TCAGCATCAA GTCCTCTGAC AGCGACGAAT CCTATGGCGA GGGCTGCATT 
GCCCTTCGGT TAGAGGCCAC AGAAACGCAG CTGCCCATCT ACACGCCTCT CACCCACCAT 
GGGGAGTTGA CAGGCCACTT CCAGGGGGAG ATCAAGCTGC AGACCTCTCA GGGCAAGACG 
AGGGAGAAGC TCTATGACTT TGTGAAGACG GAGCGTGATG AATCCAGTGG GCCAAAGACC 
CTGAAGAGCC TCACCAGCCA CGACCCCATG AAGCAGTGGG AAGTCACTAG CAGGGCCCCT 
CCGTGCAGTG GCTCCAGCAT CACTGAAATC ATCAACCCCA ACTACATGGG AGTGGGGCCC 
TTTGGGCCAC CAATGCCCCT GCACGTGAAG CAGACCTTGT CCCCTGACCA GCAGCCCACA 
GCCTGGAGCT ACGACCAGCC GCCCAAGGAC TCCCCGCTGG GGCCCTGCAG GGGAGAAAGT 
CCTCCGACAC CTCCCGGCCA GCCGCCCATA TCACCCAAGA AGTTTTTACC CTCAACAGCA 
AACCGGGGTC TCCCTCCCAG GACACAGGAG TCAAGGCCCA GTGACCTGGG GAAGAACGCA 
GGGGACACGC TGCCTCAGGA GGACCTGCCG CTGACGAAGC CCGAGATGTT TGAGAACCCC 
CTGTATGGGT CCCTGAGTTC CTTCCCTAAG CCTGCTCCCA GGAAGGACCA GGAATCCCCC 
AAAATGCCGC GGAAGGAACC CCCGCCCTGC CCGGAACCCG GCATCTTGTC GCCCAGCATC 
GTGCTCACCA AAGCCCAGGA GGCTGATCGC GGCGAGGGGC CCGGCAAGCA GGTGCCCGCG 
CCCCGGCTGC GCTCCTTCAC GTGCTCATCC TCTGCCGAGG GCAGGGCGGC CGGCGGGGAC 
AAGAGCCAAG GGAAGCCCAA GACCCCGGTC AGCTCCCAGG CCCCGGTGCC GGCCAAGAGG 
CCCATCAAGC CTTCCAGATC GGAAATCAAC CAGCAGACCC CGCCCACCCC GACGCCGCGG 
CCGCCGCTGC CAGTCAAGAG CCCGGCGGTG CTGCACCTCC AGCACTCCAA GGGCCGCGAC 
TACCGCGACA ACACCGAGCT CCCGCATCAC GGCAAGCACC GGCCGGAGGA GGGGCCACCA 
GGGCCTCTAG GCAGGACTGC CATGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017915.1
CDS	513..4082
Translation	MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTVESVVSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQLSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTFEVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ

Target ORF information:

RefSeq Version	NM_001017915.2
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017915.2

ORF Insert Sequence:

ATGGTCCCCT GCTGGAACCA TGGCAACATC ACCCGCTCCA AGGCGGAGGA GCTGCTTTCC 
AGGACAGGCA AGGACGGGAG CTTCCTCGTG CGTGCCAGCG AGTCCATCTC CCGGGCATAC 
GCGCTCTGCG TGCTGTATCG GAATTGCGTT TACACTTACA GAATTCTGCC CAATGAAGAT 
GATAAATTCA CTGTTCAGGC ATCCGAAGGC GTCTCCATGA GGTTCTTCAC CAAGCTGGAC 
CAGCTCATCG AGTTTTACAA GAAGGAAAAC ATGGGGCTGG TGACCCATCT GCAATACCCT 
GTGCCGCTGG AGGAAGAGGA CACAGGCGAC GACCCTGAGG AGGACACAGT AGAAAGTGTC 
GTGTCTCCAC CCGAGCTGCC CCCAAGAAAC ATCCCGCTGA CTGCCAGCTC CTGTGAGGCC 
AAGGAGGTTC CTTTTTCAAA CGAGAATCCC CGAGCGACCG AGACCAGCCG GCCGAGCCTC 
TCCGAGACAT TGTTCCAGCG ACTGCAAAGC ATGGACACCA GTGGGCTTCC AGAAGAGCAT 
CTTAAGGCCA TCCAAGATTA TTTAAGCACT CAGCTCGCCC AGGACTCTGA ATTTGTGAAG 
ACAGGGTCCA GCAGTCTTCC TCACCTGAAG AAACTGACCA CACTGCTCTG CAAGGAGCTC 
TATGGAGAAG TCATCCGGAC CCTCCCATCC CTGGAGTCTC TGCAGAGGTT ATTTGACCAG 
CAGCTCTCCC CGGGCCTCCG TCCACGTCCT CAGGTTCCTG GTGAGGCCAA TCCCATCAAC 
ATGGTGTCCA AGCTCAGCCA ACTGACAAGC CTGTTGTCGT CCATTGAAGA CAAGGTCAAG 
GCCTTGCTGC ACGAGGGTCC TGAGTCTCCG CACCGGCCCT CCCTTATCCC TCCAGTCACC 
TTTGAGGTGA AGGCAGAGTC TCTGGGGATT CCTCAGAAAA TGCAGCTCAA AGTCGACGTT 
GAGTCTGGGA AACTGATCAT TAAGAAGTCC AAGGATGGTT CTGAGGACAA GTTCTACAGC 
CACAAGAAAA TCCTGCAGCT CATTAAGTCA CAGAAATTTC TGAATAAGTT GGTGATCTTG 
GTGGAAACAG AGAAGGAGAA GATCCTGCGG AAGGAATATG TTTTTGCTGA CTCCAAAAAG 
AGAGAAGGCT TCTGCCAGCT CCTGCAGCAG ATGAAGAACA AGCACTCAGA GCAGCCGGAG 
CCCGACATGA TCACCATCTT CATCGGCACC TGGAACATGG GTAACGCCCC CCCTCCCAAG 
AAGATCACGT CCTGGTTTCT CTCCAAGGGG CAGGGAAAGA CGCGGGACGA CTCTGCGGAC 
TACATCCCCC ATGACATTTA CGTGATCGGC ACCCAAGAGG ACCCCCTGAG TGAGAAGGAG 
TGGCTGGAGA TCCTCAAACA CTCCCTGCAA GAAATCACCA GTGTGACTTT TAAAACAGTC 
GCCATCCACA CGCTCTGGAA CATCCGCATC GTGGTGCTGG CCAAGCCTGA GCACGAGAAC 
CGGATCAGCC ACATCTGTAC TGACAACGTG AAGACAGGCA TTGCAAACAC ACTGGGGAAC 
AAGGGAGCCG TGGGGGTGTC GTTCATGTTC AATGGAACCT CCTTAGGGTT CGTCAACAGC 
CACTTGACTT CAGGAAGTGA AAAGAAACTC AGGCGAAACC AAAACTATAT GAACATTCTC 
CGGTTCCTGG CCCTGGGCGA CAAGAAGCTG AGTCCCTTTA ACATCACTCA CCGCTTCACG 
CACCTCTTCT GGTTTGGGGA TCTTAACTAC CGTGTGGATC TGCCTACCTG GGAGGCAGAA 
ACCATCATCC AGAAAATCAA GCAGCAGCAG TACGCAGACC TCCTGTCCCA CGACCAGCTG 
CTCACAGAGA GGAGGGAGCA GAAGGTCTTC CTACACTTCG AGGAGGAAGA AATCACGTTT 
GCCCCAACCT ACCGTTTTGA GAGACTGACT CGGGACAAAT ACGCCTACAC CAAGCAGAAA 
GCGACAGGGA TGAAGTACAA CTTGCCTTCC TGGTGTGACC GAGTCCTCTG GAAGTCTTAT 
CCCCTGGTGC ACGTGGTGTG TCAGTCTTAT GGCAGTACCA GCGACATCAT GACGAGTGAC 
CACAGCCCTG TCTTTGCCAC ATTTGAGGCA GGAGTCACTT CCCAGTTTGT CTCCAAGAAC 
GGTCCCGGGA CTGTTGACAG CCAAGGACAG ATTGAGTTTC TCAGGTGCTA TGCCACATTG 
AAGACCAAGT CCCAGACCAA ATTCTACCTG GAGTTCCACT CGAGCTGCTT GGAGAGTTTT 
GTCAAGAGTC AGGAAGGAGA AAATGAAGAA GGAAGTGAGG GGGAGCTGGT GGTGAAGTTT 
GGTGAGACTC TTCCAAAGCT GAAGCCCATT ATCTCTGACC CTGAGTACCT GCTAGACCAG 
CACATCCTCA TCAGCATCAA GTCCTCTGAC AGCGACGAAT CCTATGGCGA GGGCTGCATT 
GCCCTTCGGT TAGAGGCCAC AGAAACGCAG CTGCCCATCT ACACGCCTCT CACCCACCAT 
GGGGAGTTGA CAGGCCACTT CCAGGGGGAG ATCAAGCTGC AGACCTCTCA GGGCAAGACG 
AGGGAGAAGC TCTATGACTT TGTGAAGACG GAGCGTGATG AATCCAGTGG GCCAAAGACC 
CTGAAGAGCC TCACCAGCCA CGACCCCATG AAGCAGTGGG AAGTCACTAG CAGGGCCCCT 
CCGTGCAGTG GCTCCAGCAT CACTGAAATC ATCAACCCCA ACTACATGGG AGTGGGGCCC 
TTTGGGCCAC CAATGCCCCT GCACGTGAAG CAGACCTTGT CCCCTGACCA GCAGCCCACA 
GCCTGGAGCT ACGACCAGCC GCCCAAGGAC TCCCCGCTGG GGCCCTGCAG GGGAGAAAGT 
CCTCCGACAC CTCCCGGCCA GCCGCCCATA TCACCCAAGA AGTTTTTACC CTCAACAGCA 
AACCGGGGTC TCCCTCCCAG GACACAGGAG TCAAGGCCCA GTGACCTGGG GAAGAACGCA 
GGGGACACGC TGCCTCAGGA GGACCTGCCG CTGACGAAGC CCGAGATGTT TGAGAACCCC 
CTGTATGGGT CCCTGAGTTC CTTCCCTAAG CCTGCTCCCA GGAAGGACCA GGAATCCCCC 
AAAATGCCGC GGAAGGAACC CCCGCCCTGC CCGGAACCCG GCATCTTGTC GCCCAGCATC 
GTGCTCACCA AAGCCCAGGA GGCTGATCGC GGCGAGGGGC CCGGCAAGCA GGTGCCCGCG 
CCCCGGCTGC GCTCCTTCAC GTGCTCATCC TCTGCCGAGG GCAGGGCGGC CGGCGGGGAC 
AAGAGCCAAG GGAAGCCCAA GACCCCGGTC AGCTCCCAGG CCCCGGTGCC GGCCAAGAGG 
CCCATCAAGC CTTCCAGATC GGAAATCAAC CAGCAGACCC CGCCCACCCC GACGCCGCGG 
CCGCCGCTGC CAGTCAAGAG CCCGGCGGTG CTGCACCTCC AGCACTCCAA GGGCCGCGAC 
TACCGCGACA ACACCGAGCT CCCGCATCAC GGCAAGCACC GGCCGGAGGA GGGGCCACCA 
GGGCCTCTAG GCAGGACTGC CATGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INPP5D ( NM_001017915.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001017915.1 Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 1, mRNA.

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CloneID	OHu26538
Clone ID Related Accession (Same CDS sequence)	NM_001017915.2 , NM_001017915.3
Accession Version	NM_001017915.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Homo sapiens(human)
Product	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AW503130.1, U53470.1 and BC099920.1. This sequence is a reference standard in the RefSeqGene project. On Nov 24, 2018 this sequence version replaced NM_001017915.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.38964.1, U84400.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000445964.6/ ENSP00000405338.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTCCCCT GCTGGAACCA TGGCAACATC ACCCGCTCCA AGGCGGAGGA GCTGCTTTCC 
AGGACAGGCA AGGACGGGAG CTTCCTCGTG CGTGCCAGCG AGTCCATCTC CCGGGCATAC 
GCGCTCTGCG TGCTGTATCG GAATTGCGTT TACACTTACA GAATTCTGCC CAATGAAGAT 
GATAAATTCA CTGTTCAGGC ATCCGAAGGC GTCTCCATGA GGTTCTTCAC CAAGCTGGAC 
CAGCTCATCG AGTTTTACAA GAAGGAAAAC ATGGGGCTGG TGACCCATCT GCAATACCCT 
GTGCCGCTGG AGGAAGAGGA CACAGGCGAC GACCCTGAGG AGGACACAGT AGAAAGTGTC 
GTGTCTCCAC CCGAGCTGCC CCCAAGAAAC ATCCCGCTGA CTGCCAGCTC CTGTGAGGCC 
AAGGAGGTTC CTTTTTCAAA CGAGAATCCC CGAGCGACCG AGACCAGCCG GCCGAGCCTC 
TCCGAGACAT TGTTCCAGCG ACTGCAAAGC ATGGACACCA GTGGGCTTCC AGAAGAGCAT 
CTTAAGGCCA TCCAAGATTA TTTAAGCACT CAGCTCGCCC AGGACTCTGA ATTTGTGAAG 
ACAGGGTCCA GCAGTCTTCC TCACCTGAAG AAACTGACCA CACTGCTCTG CAAGGAGCTC 
TATGGAGAAG TCATCCGGAC CCTCCCATCC CTGGAGTCTC TGCAGAGGTT ATTTGACCAG 
CAGCTCTCCC CGGGCCTCCG TCCACGTCCT CAGGTTCCTG GTGAGGCCAA TCCCATCAAC 
ATGGTGTCCA AGCTCAGCCA ACTGACAAGC CTGTTGTCGT CCATTGAAGA CAAGGTCAAG 
GCCTTGCTGC ACGAGGGTCC TGAGTCTCCG CACCGGCCCT CCCTTATCCC TCCAGTCACC 
TTTGAGGTGA AGGCAGAGTC TCTGGGGATT CCTCAGAAAA TGCAGCTCAA AGTCGACGTT 
GAGTCTGGGA AACTGATCAT TAAGAAGTCC AAGGATGGTT CTGAGGACAA GTTCTACAGC 
CACAAGAAAA TCCTGCAGCT CATTAAGTCA CAGAAATTTC TGAATAAGTT GGTGATCTTG 
GTGGAAACAG AGAAGGAGAA GATCCTGCGG AAGGAATATG TTTTTGCTGA CTCCAAAAAG 
AGAGAAGGCT TCTGCCAGCT CCTGCAGCAG ATGAAGAACA AGCACTCAGA GCAGCCGGAG 
CCCGACATGA TCACCATCTT CATCGGCACC TGGAACATGG GTAACGCCCC CCCTCCCAAG 
AAGATCACGT CCTGGTTTCT CTCCAAGGGG CAGGGAAAGA CGCGGGACGA CTCTGCGGAC 
TACATCCCCC ATGACATTTA CGTGATCGGC ACCCAAGAGG ACCCCCTGAG TGAGAAGGAG 
TGGCTGGAGA TCCTCAAACA CTCCCTGCAA GAAATCACCA GTGTGACTTT TAAAACAGTC 
GCCATCCACA CGCTCTGGAA CATCCGCATC GTGGTGCTGG CCAAGCCTGA GCACGAGAAC 
CGGATCAGCC ACATCTGTAC TGACAACGTG AAGACAGGCA TTGCAAACAC ACTGGGGAAC 
AAGGGAGCCG TGGGGGTGTC GTTCATGTTC AATGGAACCT CCTTAGGGTT CGTCAACAGC 
CACTTGACTT CAGGAAGTGA AAAGAAACTC AGGCGAAACC AAAACTATAT GAACATTCTC 
CGGTTCCTGG CCCTGGGCGA CAAGAAGCTG AGTCCCTTTA ACATCACTCA CCGCTTCACG 
CACCTCTTCT GGTTTGGGGA TCTTAACTAC CGTGTGGATC TGCCTACCTG GGAGGCAGAA 
ACCATCATCC AGAAAATCAA GCAGCAGCAG TACGCAGACC TCCTGTCCCA CGACCAGCTG 
CTCACAGAGA GGAGGGAGCA GAAGGTCTTC CTACACTTCG AGGAGGAAGA AATCACGTTT 
GCCCCAACCT ACCGTTTTGA GAGACTGACT CGGGACAAAT ACGCCTACAC CAAGCAGAAA 
GCGACAGGGA TGAAGTACAA CTTGCCTTCC TGGTGTGACC GAGTCCTCTG GAAGTCTTAT 
CCCCTGGTGC ACGTGGTGTG TCAGTCTTAT GGCAGTACCA GCGACATCAT GACGAGTGAC 
CACAGCCCTG TCTTTGCCAC ATTTGAGGCA GGAGTCACTT CCCAGTTTGT CTCCAAGAAC 
GGTCCCGGGA CTGTTGACAG CCAAGGACAG ATTGAGTTTC TCAGGTGCTA TGCCACATTG 
AAGACCAAGT CCCAGACCAA ATTCTACCTG GAGTTCCACT CGAGCTGCTT GGAGAGTTTT 
GTCAAGAGTC AGGAAGGAGA AAATGAAGAA GGAAGTGAGG GGGAGCTGGT GGTGAAGTTT 
GGTGAGACTC TTCCAAAGCT GAAGCCCATT ATCTCTGACC CTGAGTACCT GCTAGACCAG 
CACATCCTCA TCAGCATCAA GTCCTCTGAC AGCGACGAAT CCTATGGCGA GGGCTGCATT 
GCCCTTCGGT TAGAGGCCAC AGAAACGCAG CTGCCCATCT ACACGCCTCT CACCCACCAT 
GGGGAGTTGA CAGGCCACTT CCAGGGGGAG ATCAAGCTGC AGACCTCTCA GGGCAAGACG 
AGGGAGAAGC TCTATGACTT TGTGAAGACG GAGCGTGATG AATCCAGTGG GCCAAAGACC 
CTGAAGAGCC TCACCAGCCA CGACCCCATG AAGCAGTGGG AAGTCACTAG CAGGGCCCCT 
CCGTGCAGTG GCTCCAGCAT CACTGAAATC ATCAACCCCA ACTACATGGG AGTGGGGCCC 
TTTGGGCCAC CAATGCCCCT GCACGTGAAG CAGACCTTGT CCCCTGACCA GCAGCCCACA 
GCCTGGAGCT ACGACCAGCC GCCCAAGGAC TCCCCGCTGG GGCCCTGCAG GGGAGAAAGT 
CCTCCGACAC CTCCCGGCCA GCCGCCCATA TCACCCAAGA AGTTTTTACC CTCAACAGCA 
AACCGGGGTC TCCCTCCCAG GACACAGGAG TCAAGGCCCA GTGACCTGGG GAAGAACGCA 
GGGGACACGC TGCCTCAGGA GGACCTGCCG CTGACGAAGC CCGAGATGTT TGAGAACCCC 
CTGTATGGGT CCCTGAGTTC CTTCCCTAAG CCTGCTCCCA GGAAGGACCA GGAATCCCCC 
AAAATGCCGC GGAAGGAACC CCCGCCCTGC CCGGAACCCG GCATCTTGTC GCCCAGCATC 
GTGCTCACCA AAGCCCAGGA GGCTGATCGC GGCGAGGGGC CCGGCAAGCA GGTGCCCGCG 
CCCCGGCTGC GCTCCTTCAC GTGCTCATCC TCTGCCGAGG GCAGGGCGGC CGGCGGGGAC 
AAGAGCCAAG GGAAGCCCAA GACCCCGGTC AGCTCCCAGG CCCCGGTGCC GGCCAAGAGG 
CCCATCAAGC CTTCCAGATC GGAAATCAAC CAGCAGACCC CGCCCACCCC GACGCCGCGG 
CCGCCGCTGC CAGTCAAGAG CCCGGCGGTG CTGCACCTCC AGCACTCCAA GGGCCGCGAC 
TACCGCGACA ACACCGAGCT CCCGCATCAC GGCAAGCACC GGCCGGAGGA GGGGCCACCA 
GGGCCTCTAG GCAGGACTGC CATGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017915.1
CDS	138..3707
Translation	MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTVESVVSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQLSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTFEVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ

Target ORF information:

RefSeq Version	NM_001017915.3
Organism	Homo sapiens(human)
Definition	Homo sapiens inositol polyphosphate-5-phosphatase D (INPP5D), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017915.3

ORF Insert Sequence:

ATGGTCCCCT GCTGGAACCA TGGCAACATC ACCCGCTCCA AGGCGGAGGA GCTGCTTTCC 
AGGACAGGCA AGGACGGGAG CTTCCTCGTG CGTGCCAGCG AGTCCATCTC CCGGGCATAC 
GCGCTCTGCG TGCTGTATCG GAATTGCGTT TACACTTACA GAATTCTGCC CAATGAAGAT 
GATAAATTCA CTGTTCAGGC ATCCGAAGGC GTCTCCATGA GGTTCTTCAC CAAGCTGGAC 
CAGCTCATCG AGTTTTACAA GAAGGAAAAC ATGGGGCTGG TGACCCATCT GCAATACCCT 
GTGCCGCTGG AGGAAGAGGA CACAGGCGAC GACCCTGAGG AGGACACAGT AGAAAGTGTC 
GTGTCTCCAC CCGAGCTGCC CCCAAGAAAC ATCCCGCTGA CTGCCAGCTC CTGTGAGGCC 
AAGGAGGTTC CTTTTTCAAA CGAGAATCCC CGAGCGACCG AGACCAGCCG GCCGAGCCTC 
TCCGAGACAT TGTTCCAGCG ACTGCAAAGC ATGGACACCA GTGGGCTTCC AGAAGAGCAT 
CTTAAGGCCA TCCAAGATTA TTTAAGCACT CAGCTCGCCC AGGACTCTGA ATTTGTGAAG 
ACAGGGTCCA GCAGTCTTCC TCACCTGAAG AAACTGACCA CACTGCTCTG CAAGGAGCTC 
TATGGAGAAG TCATCCGGAC CCTCCCATCC CTGGAGTCTC TGCAGAGGTT ATTTGACCAG 
CAGCTCTCCC CGGGCCTCCG TCCACGTCCT CAGGTTCCTG GTGAGGCCAA TCCCATCAAC 
ATGGTGTCCA AGCTCAGCCA ACTGACAAGC CTGTTGTCGT CCATTGAAGA CAAGGTCAAG 
GCCTTGCTGC ACGAGGGTCC TGAGTCTCCG CACCGGCCCT CCCTTATCCC TCCAGTCACC 
TTTGAGGTGA AGGCAGAGTC TCTGGGGATT CCTCAGAAAA TGCAGCTCAA AGTCGACGTT 
GAGTCTGGGA AACTGATCAT TAAGAAGTCC AAGGATGGTT CTGAGGACAA GTTCTACAGC 
CACAAGAAAA TCCTGCAGCT CATTAAGTCA CAGAAATTTC TGAATAAGTT GGTGATCTTG 
GTGGAAACAG AGAAGGAGAA GATCCTGCGG AAGGAATATG TTTTTGCTGA CTCCAAAAAG 
AGAGAAGGCT TCTGCCAGCT CCTGCAGCAG ATGAAGAACA AGCACTCAGA GCAGCCGGAG 
CCCGACATGA TCACCATCTT CATCGGCACC TGGAACATGG GTAACGCCCC CCCTCCCAAG 
AAGATCACGT CCTGGTTTCT CTCCAAGGGG CAGGGAAAGA CGCGGGACGA CTCTGCGGAC 
TACATCCCCC ATGACATTTA CGTGATCGGC ACCCAAGAGG ACCCCCTGAG TGAGAAGGAG 
TGGCTGGAGA TCCTCAAACA CTCCCTGCAA GAAATCACCA GTGTGACTTT TAAAACAGTC 
GCCATCCACA CGCTCTGGAA CATCCGCATC GTGGTGCTGG CCAAGCCTGA GCACGAGAAC 
CGGATCAGCC ACATCTGTAC TGACAACGTG AAGACAGGCA TTGCAAACAC ACTGGGGAAC 
AAGGGAGCCG TGGGGGTGTC GTTCATGTTC AATGGAACCT CCTTAGGGTT CGTCAACAGC 
CACTTGACTT CAGGAAGTGA AAAGAAACTC AGGCGAAACC AAAACTATAT GAACATTCTC 
CGGTTCCTGG CCCTGGGCGA CAAGAAGCTG AGTCCCTTTA ACATCACTCA CCGCTTCACG 
CACCTCTTCT GGTTTGGGGA TCTTAACTAC CGTGTGGATC TGCCTACCTG GGAGGCAGAA 
ACCATCATCC AGAAAATCAA GCAGCAGCAG TACGCAGACC TCCTGTCCCA CGACCAGCTG 
CTCACAGAGA GGAGGGAGCA GAAGGTCTTC CTACACTTCG AGGAGGAAGA AATCACGTTT 
GCCCCAACCT ACCGTTTTGA GAGACTGACT CGGGACAAAT ACGCCTACAC CAAGCAGAAA 
GCGACAGGGA TGAAGTACAA CTTGCCTTCC TGGTGTGACC GAGTCCTCTG GAAGTCTTAT 
CCCCTGGTGC ACGTGGTGTG TCAGTCTTAT GGCAGTACCA GCGACATCAT GACGAGTGAC 
CACAGCCCTG TCTTTGCCAC ATTTGAGGCA GGAGTCACTT CCCAGTTTGT CTCCAAGAAC 
GGTCCCGGGA CTGTTGACAG CCAAGGACAG ATTGAGTTTC TCAGGTGCTA TGCCACATTG 
AAGACCAAGT CCCAGACCAA ATTCTACCTG GAGTTCCACT CGAGCTGCTT GGAGAGTTTT 
GTCAAGAGTC AGGAAGGAGA AAATGAAGAA GGAAGTGAGG GGGAGCTGGT GGTGAAGTTT 
GGTGAGACTC TTCCAAAGCT GAAGCCCATT ATCTCTGACC CTGAGTACCT GCTAGACCAG 
CACATCCTCA TCAGCATCAA GTCCTCTGAC AGCGACGAAT CCTATGGCGA GGGCTGCATT 
GCCCTTCGGT TAGAGGCCAC AGAAACGCAG CTGCCCATCT ACACGCCTCT CACCCACCAT 
GGGGAGTTGA CAGGCCACTT CCAGGGGGAG ATCAAGCTGC AGACCTCTCA GGGCAAGACG 
AGGGAGAAGC TCTATGACTT TGTGAAGACG GAGCGTGATG AATCCAGTGG GCCAAAGACC 
CTGAAGAGCC TCACCAGCCA CGACCCCATG AAGCAGTGGG AAGTCACTAG CAGGGCCCCT 
CCGTGCAGTG GCTCCAGCAT CACTGAAATC ATCAACCCCA ACTACATGGG AGTGGGGCCC 
TTTGGGCCAC CAATGCCCCT GCACGTGAAG CAGACCTTGT CCCCTGACCA GCAGCCCACA 
GCCTGGAGCT ACGACCAGCC GCCCAAGGAC TCCCCGCTGG GGCCCTGCAG GGGAGAAAGT 
CCTCCGACAC CTCCCGGCCA GCCGCCCATA TCACCCAAGA AGTTTTTACC CTCAACAGCA 
AACCGGGGTC TCCCTCCCAG GACACAGGAG TCAAGGCCCA GTGACCTGGG GAAGAACGCA 
GGGGACACGC TGCCTCAGGA GGACCTGCCG CTGACGAAGC CCGAGATGTT TGAGAACCCC 
CTGTATGGGT CCCTGAGTTC CTTCCCTAAG CCTGCTCCCA GGAAGGACCA GGAATCCCCC 
AAAATGCCGC GGAAGGAACC CCCGCCCTGC CCGGAACCCG GCATCTTGTC GCCCAGCATC 
GTGCTCACCA AAGCCCAGGA GGCTGATCGC GGCGAGGGGC CCGGCAAGCA GGTGCCCGCG 
CCCCGGCTGC GCTCCTTCAC GTGCTCATCC TCTGCCGAGG GCAGGGCGGC CGGCGGGGAC 
AAGAGCCAAG GGAAGCCCAA GACCCCGGTC AGCTCCCAGG CCCCGGTGCC GGCCAAGAGG 
CCCATCAAGC CTTCCAGATC GGAAATCAAC CAGCAGACCC CGCCCACCCC GACGCCGCGG 
CCGCCGCTGC CAGTCAAGAG CCCGGCGGTG CTGCACCTCC AGCACTCCAA GGGCCGCGAC 
TACCGCGACA ACACCGAGCT CCCGCATCAC GGCAAGCACC GGCCGGAGGA GGGGCCACCA 
GGGCCTCTAG GCAGGACTGC CATGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory Fc?RIIB.
Journal of immunology (Baltimore, Md. : 1950)(2018 Jan)
Stopforth RJ,Oldham RJ,Tutt AL,Duriez P,Chan HTC,Binkowski BF,Zimprich C,Li D,Hargreaves PG,Cong M,Reddy V,Leandro MJ,Cambridge G,Lux A,Nimmerjahn F,Cragg MS

Analysis of SHIP1 expression and activity in Crohn's disease patients.
PloS one12(8)e0182308(2017)
Somasundaram R,Fernandes S,Deuring JJ,de Haar C,Kuipers EJ,Vogelaar L,Middleton FA,van der Woude CJ,Peppelenbosch MP,Kerr WG,Fuhler GM

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INPP5D cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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