ILF2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ILF2
Entrez Gene ID	3608
Full Name	interleukin enhancer binding factor 2
Synonyms	NF45,PRO3063
General protein information	Preferred Names interleukin enhancer binding factor 2 Names interleukin enhancer-binding factor 2 interleukin enhancer binding factor 2, 45kD interleukin enhancer binding factor 2, 45kDa nuclear factor of activated T-cells, 45-kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q21.3
Summary	The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014].
Disorder MIM:	603181

mRNA and Protein(s)

mRNA	Protein	Name
NM_004515.4	NP_004506.2	interleukin enhancer-binding factor 2 isoform 1
NM_001267809.1	NP_001254738.1	interleukin enhancer-binding factor 2 isoform 2
NM_004515.3	NP_004506.2	interleukin enhancer-binding factor 2 isoform 1

Pathways from BioSystems

Homologies

	ILF2	XP_001111422.1
Mus musculus (house mouse)	Ilf2	NP_080650.1
Gallus gallus (chicken)	ILF2	XP_004948269.1
Pan troglodytes (chimpanzee)	ILF2	XP_001142785.1
Canis lupus familiaris (dog)	ILF2	XP_537263.1
Drosophila melanogaster (fruit fly)	CG5641	NP_650196.1
Danio rerio (zebrafish)	ilf2	NP_998401.1
Homo sapiens (human)	ILF2	NP_004506.2
Bos taurus (cattle)	ILF2	NP_001033276.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001997	XP_321062.4
Caenorhabditis elegans (roundworm)	CELE_R11H6.5	NP_506614.1

Gene Ontology
Bibliography

Related articles in PubMed

ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma.
Marchesini M, Ogoti Y, Fiorini E, Aktas Samur A, Nezi L, D'Anca M, Storti P, Samur MK, Ganan-Gomez I, Fulciniti MT, Mistry N, Jiang S, Bao N, Marchica V, Neri A, Bueso-Ramos C, Wu CJ, Zhang L, Liang H, Peng X, Giuliani N, Draetta G, Clise-Dwyer K, Kantarjian H, Munshi N, Orlowski R, Garcia-Manero G, DePinho RA, Colla S
Cancer cell32(1)88-100.e6(2017 Jul)

Expression and Clinical Significance of ILF2 in Gastric Cancer.
Yin ZH, Jiang XW, Shi WB, Gui QL, Yu DF
Disease markers20174387081(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ILF2 interacts with RNA-binding proteins involved in the DNA damage response.
Title: ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma.

The results revealed that ILF2 is regulated by miR-7 and suggest that downregulation of miR-7 may be an important factor for the ILF2 overexpression in pancreatic carcinoma.
Title: MicroRNA-7 functions as a tumor-suppressor gene by regulating ILF2 in pancreatic carcinoma.

The data suggest that features of both the N- and C-termini of NF90 participate in the heterodimerization with NF45 and that the formation of NF90-NF45 changes the conformation of NF90's RNA-binding motifs to a status in which the co-operative interplay of the RNA-binding motifs is optimal.
Title: The properties of the RNA-binding protein NF90 are considerably modulated by complex formation with NF45.

NF90-NF45 stimulates an elevation of EGF receptor levels via the suppression of miR-7 biogenesis, resulting in the promotion of cell proliferation in Hepatocellular Carcinoma.
Title: Suppression of MicroRNA-7 (miR-7) Biogenesis by Nuclear Factor 90-Nuclear Factor 45 Complex (NF90-NF45) Controls Cell Proliferation in Hepatocellular Carcinoma.

Deletion of the RNA binding domains of NF45 and NF90 diminished the enhancement of HIV infection and gene expression.
Title: NF45 and NF90 Bind HIV-1 RNA and Modulate HIV Gene Expression.

The following ILF2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ILF2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03626	NM_001267809.1 Latest version!	Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu04423	NM_004515.4 Latest version!	Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu04423	NM_004515.3	Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ILF2 ( NM_001267809.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254738.1 Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03626
Clone ID Related Accession (Same CDS sequence)	NM_001267809.1
Accession Version	NM_001267809.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Homo sapiens(human)
Product	interleukin enhancer-binding factor 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC412988.1, AK223326.1, AK302214.1, BC000382.2 and BX450311.2. Transcript Variant: This variant (2) uses an alternate splice site in its 5' UTR and uses an in-frame downstream start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.366480.1, SRR1803611.139019.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTTC CCCGGGTCAA GCCAGCACCT GATGAAACTT CCTTCAGTGA GGCCTTGCTG 
AAGAGGAATC AGGACCTGGC TCCCAATTCT GCTGAACAGG CATCTATCCT TTCTCTGGTG 
ACAAAAATAA ACAATGTGAT TGATAATCTG ATTGTGGCTC CAGGGACATT TGAAGTGCAA 
ATTGAAGAAG TTCGACAGGT GGGATCCTAT AAAAAGGGGA CAATGACTAC AGGACACAAT 
GTGGCTGACC TGGTGGTGAT ACTCAAGATT CTGCCAACGT TGGAAGCTGT TGCTGCCCTG 
GGGAACAAAG TCGTGGAAAG CCTAAGAGCA CAGGATCCTT CTGAAGTTTT AACCATGCTG 
ACCAACGAAA CTGGCTTTGA AATCAGTTCT TCTGATGCTA CAGTGAAGAT TCTCATTACA 
ACAGTGCCAC CCAATCTTCG AAAACTGGAT CCAGAACTCC ATTTGGATAT CAAAGTATTG 
CAGAGTGCCT TAGCAGCCAT CCGACATGCC CGCTGGTTCG AGGAAAATGC TTCTCAGTCC 
ACAGTTAAAG TTCTCATCAG ACTACTGAAG GACTTGAGGA TTCGTTTTCC TGGCTTTGAG 
CCCCTCACAC CCTGGATCCT TGACCTACTA GGCCATTATG CTGTGATGAA CAACCCCACC 
AGACAGCCTT TGGCCCTAAA CGTTGCATAC AGGCGCTGCT TGCAGATTCT GGCTGCAGGA 
CTGTTCCTGC CAGGTTCAGT GGGTATCACT GACCCCTGTG AGAGTGGCAA CTTTAGAGTA 
CACACAGTCA TGACCCTAGA ACAGCAGGAC ATGGTCTGCT ATACAGCTCA GACTCTCGTC 
CGAATCCTCT CACATGGTGG CTTTAGGAAG ATCCTTGGCC AGGAGGGTGA TGCCAGCTAT 
CTTGCTTCTG AAATATCTAC CTGGGATGGA GTGATAGTAA CACCTTCAGA AAAGGCTTAT 
GAGAAGCCAC CAGAGAAGAA GGAAGGAGAG GAAGAAGAGG AGAATACAGA AGAACCACCT 
CAAGGAGAGG AAGAAGAAAG CATGGAAACT CAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254738.1
CDS	240..1298
Translation	MAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE

Target ORF information:

RefSeq Version	NM_001267809.1
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267809.1

ORF Insert Sequence:

ATGGCCTTTC CCCGGGTCAA GCCAGCACCT GATGAAACTT CCTTCAGTGA GGCCTTGCTG 
AAGAGGAATC AGGACCTGGC TCCCAATTCT GCTGAACAGG CATCTATCCT TTCTCTGGTG 
ACAAAAATAA ACAATGTGAT TGATAATCTG ATTGTGGCTC CAGGGACATT TGAAGTGCAA 
ATTGAAGAAG TTCGACAGGT GGGATCCTAT AAAAAGGGGA CAATGACTAC AGGACACAAT 
GTGGCTGACC TGGTGGTGAT ACTCAAGATT CTGCCAACGT TGGAAGCTGT TGCTGCCCTG 
GGGAACAAAG TCGTGGAAAG CCTAAGAGCA CAGGATCCTT CTGAAGTTTT AACCATGCTG 
ACCAACGAAA CTGGCTTTGA AATCAGTTCT TCTGATGCTA CAGTGAAGAT TCTCATTACA 
ACAGTGCCAC CCAATCTTCG AAAACTGGAT CCAGAACTCC ATTTGGATAT CAAAGTATTG 
CAGAGTGCCT TAGCAGCCAT CCGACATGCC CGCTGGTTCG AGGAAAATGC TTCTCAGTCC 
ACAGTTAAAG TTCTCATCAG ACTACTGAAG GACTTGAGGA TTCGTTTTCC TGGCTTTGAG 
CCCCTCACAC CCTGGATCCT TGACCTACTA GGCCATTATG CTGTGATGAA CAACCCCACC 
AGACAGCCTT TGGCCCTAAA CGTTGCATAC AGGCGCTGCT TGCAGATTCT GGCTGCAGGA 
CTGTTCCTGC CAGGTTCAGT GGGTATCACT GACCCCTGTG AGAGTGGCAA CTTTAGAGTA 
CACACAGTCA TGACCCTAGA ACAGCAGGAC ATGGTCTGCT ATACAGCTCA GACTCTCGTC 
CGAATCCTCT CACATGGTGG CTTTAGGAAG ATCCTTGGCC AGGAGGGTGA TGCCAGCTAT 
CTTGCTTCTG AAATATCTAC CTGGGATGGA GTGATAGTAA CACCTTCAGA AAAGGCTTAT 
GAGAAGCCAC CAGAGAAGAA GGAAGGAGAG GAAGAAGAGG AGAATACAGA AGAACCACCT 
CAAGGAGAGG AAGAAGAAAG CATGGAAACT CAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ILF2 ( NM_004515.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004506.2 Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04423
Clone ID Related Accession (Same CDS sequence)	NM_004515.4 , NM_004515.3
Accession Version	NM_004515.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	interleukin enhancer-binding factor 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC412988.1, AK223326.1, BC000382.2 and BX450311.2. On Nov 23, 2018 this sequence version replaced NM_004515.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.65850.1, SRR1803616.206013.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000361891.9/ ENSP00000355011.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGGGTG ACAGAGGCCG TGGTCGTGGT GGGCGCTTTG GTTCCAGAGG AGGCCCAGGA 
GGAGGGTTCA GGCCCTTTGT ACCACATATC CCATTTGACT TCTATTTGTG TGAAATGGCC 
TTTCCCCGGG TCAAGCCAGC ACCTGATGAA ACTTCCTTCA GTGAGGCCTT GCTGAAGAGG 
AATCAGGACC TGGCTCCCAA TTCTGCTGAA CAGGCATCTA TCCTTTCTCT GGTGACAAAA 
ATAAACAATG TGATTGATAA TCTGATTGTG GCTCCAGGGA CATTTGAAGT GCAAATTGAA 
GAAGTTCGAC AGGTGGGATC CTATAAAAAG GGGACAATGA CTACAGGACA CAATGTGGCT 
GACCTGGTGG TGATACTCAA GATTCTGCCA ACGTTGGAAG CTGTTGCTGC CCTGGGGAAC 
AAAGTCGTGG AAAGCCTAAG AGCACAGGAT CCTTCTGAAG TTTTAACCAT GCTGACCAAC 
GAAACTGGCT TTGAAATCAG TTCTTCTGAT GCTACAGTGA AGATTCTCAT TACAACAGTG 
CCACCCAATC TTCGAAAACT GGATCCAGAA CTCCATTTGG ATATCAAAGT ATTGCAGAGT 
GCCTTAGCAG CCATCCGACA TGCCCGCTGG TTCGAGGAAA ATGCTTCTCA GTCCACAGTT 
AAAGTTCTCA TCAGACTACT GAAGGACTTG AGGATTCGTT TTCCTGGCTT TGAGCCCCTC 
ACACCCTGGA TCCTTGACCT ACTAGGCCAT TATGCTGTGA TGAACAACCC CACCAGACAG 
CCTTTGGCCC TAAACGTTGC ATACAGGCGC TGCTTGCAGA TTCTGGCTGC AGGACTGTTC 
CTGCCAGGTT CAGTGGGTAT CACTGACCCC TGTGAGAGTG GCAACTTTAG AGTACACACA 
GTCATGACCC TAGAACAGCA GGACATGGTC TGCTATACAG CTCAGACTCT CGTCCGAATC 
CTCTCACATG GTGGCTTTAG GAAGATCCTT GGCCAGGAGG GTGATGCCAG CTATCTTGCT 
TCTGAAATAT CTACCTGGGA TGGAGTGATA GTAACACCTT CAGAAAAGGC TTATGAGAAG 
CCACCAGAGA AGAAGGAAGG AGAGGAAGAA GAGGAGAATA CAGAAGAACC ACCTCAAGGA 
GAGGAAGAAG AAAGCATGGA AACTCAGGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004506.2
CDS	72..1244
Translation	MRGDRGRGRGGRFGSRGGPGGGFRPFVPHIPFDFYLCEMAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE

Target ORF information:

RefSeq Version	NM_004515.4
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004515.4

ORF Insert Sequence:

ATGAGGGGTG ACAGAGGCCG TGGTCGTGGT GGGCGCTTTG GTTCCAGAGG AGGCCCAGGA 
GGAGGGTTCA GGCCCTTTGT ACCACATATC CCATTTGACT TCTATTTGTG TGAAATGGCC 
TTTCCCCGGG TCAAGCCAGC ACCTGATGAA ACTTCCTTCA GTGAGGCCTT GCTGAAGAGG 
AATCAGGACC TGGCTCCCAA TTCTGCTGAA CAGGCATCTA TCCTTTCTCT GGTGACAAAA 
ATAAACAATG TGATTGATAA TCTGATTGTG GCTCCAGGGA CATTTGAAGT GCAAATTGAA 
GAAGTTCGAC AGGTGGGATC CTATAAAAAG GGGACAATGA CTACAGGACA CAATGTGGCT 
GACCTGGTGG TGATACTCAA GATTCTGCCA ACGTTGGAAG CTGTTGCTGC CCTGGGGAAC 
AAAGTCGTGG AAAGCCTAAG AGCACAGGAT CCTTCTGAAG TTTTAACCAT GCTGACCAAC 
GAAACTGGCT TTGAAATCAG TTCTTCTGAT GCTACAGTGA AGATTCTCAT TACAACAGTG 
CCACCCAATC TTCGAAAACT GGATCCAGAA CTCCATTTGG ATATCAAAGT ATTGCAGAGT 
GCCTTAGCAG CCATCCGACA TGCCCGCTGG TTCGAGGAAA ATGCTTCTCA GTCCACAGTT 
AAAGTTCTCA TCAGACTACT GAAGGACTTG AGGATTCGTT TTCCTGGCTT TGAGCCCCTC 
ACACCCTGGA TCCTTGACCT ACTAGGCCAT TATGCTGTGA TGAACAACCC CACCAGACAG 
CCTTTGGCCC TAAACGTTGC ATACAGGCGC TGCTTGCAGA TTCTGGCTGC AGGACTGTTC 
CTGCCAGGTT CAGTGGGTAT CACTGACCCC TGTGAGAGTG GCAACTTTAG AGTACACACA 
GTCATGACCC TAGAACAGCA GGACATGGTC TGCTATACAG CTCAGACTCT CGTCCGAATC 
CTCTCACATG GTGGCTTTAG GAAGATCCTT GGCCAGGAGG GTGATGCCAG CTATCTTGCT 
TCTGAAATAT CTACCTGGGA TGGAGTGATA GTAACACCTT CAGAAAAGGC TTATGAGAAG 
CCACCAGAGA AGAAGGAAGG AGAGGAAGAA GAGGAGAATA CAGAAGAACC ACCTCAAGGA 
GAGGAAGAAG AAAGCATGGA AACTCAGGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ILF2 ( NM_004515.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004506.2 Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04423
Clone ID Related Accession (Same CDS sequence)	NM_004515.4 , NM_004515.3
Accession Version	NM_004515.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	interleukin enhancer-binding factor 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC412988.1, AK223326.1, BC000382.2 and BX450311.2. On Jun 22, 2012 this sequence version replaced NM_004515.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.144993.1, SRR1803616.206013.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGGGTG ACAGAGGCCG TGGTCGTGGT GGGCGCTTTG GTTCCAGAGG AGGCCCAGGA 
GGAGGGTTCA GGCCCTTTGT ACCACATATC CCATTTGACT TCTATTTGTG TGAAATGGCC 
TTTCCCCGGG TCAAGCCAGC ACCTGATGAA ACTTCCTTCA GTGAGGCCTT GCTGAAGAGG 
AATCAGGACC TGGCTCCCAA TTCTGCTGAA CAGGCATCTA TCCTTTCTCT GGTGACAAAA 
ATAAACAATG TGATTGATAA TCTGATTGTG GCTCCAGGGA CATTTGAAGT GCAAATTGAA 
GAAGTTCGAC AGGTGGGATC CTATAAAAAG GGGACAATGA CTACAGGACA CAATGTGGCT 
GACCTGGTGG TGATACTCAA GATTCTGCCA ACGTTGGAAG CTGTTGCTGC CCTGGGGAAC 
AAAGTCGTGG AAAGCCTAAG AGCACAGGAT CCTTCTGAAG TTTTAACCAT GCTGACCAAC 
GAAACTGGCT TTGAAATCAG TTCTTCTGAT GCTACAGTGA AGATTCTCAT TACAACAGTG 
CCACCCAATC TTCGAAAACT GGATCCAGAA CTCCATTTGG ATATCAAAGT ATTGCAGAGT 
GCCTTAGCAG CCATCCGACA TGCCCGCTGG TTCGAGGAAA ATGCTTCTCA GTCCACAGTT 
AAAGTTCTCA TCAGACTACT GAAGGACTTG AGGATTCGTT TTCCTGGCTT TGAGCCCCTC 
ACACCCTGGA TCCTTGACCT ACTAGGCCAT TATGCTGTGA TGAACAACCC CACCAGACAG 
CCTTTGGCCC TAAACGTTGC ATACAGGCGC TGCTTGCAGA TTCTGGCTGC AGGACTGTTC 
CTGCCAGGTT CAGTGGGTAT CACTGACCCC TGTGAGAGTG GCAACTTTAG AGTACACACA 
GTCATGACCC TAGAACAGCA GGACATGGTC TGCTATACAG CTCAGACTCT CGTCCGAATC 
CTCTCACATG GTGGCTTTAG GAAGATCCTT GGCCAGGAGG GTGATGCCAG CTATCTTGCT 
TCTGAAATAT CTACCTGGGA TGGAGTGATA GTAACACCTT CAGAAAAGGC TTATGAGAAG 
CCACCAGAGA AGAAGGAAGG AGAGGAAGAA GAGGAGAATA CAGAAGAACC ACCTCAAGGA 
GAGGAAGAAG AAAGCATGGA AACTCAGGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004506.2
CDS	107..1279
Translation	MRGDRGRGRGGRFGSRGGPGGGFRPFVPHIPFDFYLCEMAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE

Target ORF information:

RefSeq Version	NM_004515.3
Organism	Homo sapiens(human)
Definition	Homo sapiens interleukin enhancer binding factor 2 (ILF2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004515.3

ORF Insert Sequence:

ATGAGGGGTG ACAGAGGCCG TGGTCGTGGT GGGCGCTTTG GTTCCAGAGG AGGCCCAGGA 
GGAGGGTTCA GGCCCTTTGT ACCACATATC CCATTTGACT TCTATTTGTG TGAAATGGCC 
TTTCCCCGGG TCAAGCCAGC ACCTGATGAA ACTTCCTTCA GTGAGGCCTT GCTGAAGAGG 
AATCAGGACC TGGCTCCCAA TTCTGCTGAA CAGGCATCTA TCCTTTCTCT GGTGACAAAA 
ATAAACAATG TGATTGATAA TCTGATTGTG GCTCCAGGGA CATTTGAAGT GCAAATTGAA 
GAAGTTCGAC AGGTGGGATC CTATAAAAAG GGGACAATGA CTACAGGACA CAATGTGGCT 
GACCTGGTGG TGATACTCAA GATTCTGCCA ACGTTGGAAG CTGTTGCTGC CCTGGGGAAC 
AAAGTCGTGG AAAGCCTAAG AGCACAGGAT CCTTCTGAAG TTTTAACCAT GCTGACCAAC 
GAAACTGGCT TTGAAATCAG TTCTTCTGAT GCTACAGTGA AGATTCTCAT TACAACAGTG 
CCACCCAATC TTCGAAAACT GGATCCAGAA CTCCATTTGG ATATCAAAGT ATTGCAGAGT 
GCCTTAGCAG CCATCCGACA TGCCCGCTGG TTCGAGGAAA ATGCTTCTCA GTCCACAGTT 
AAAGTTCTCA TCAGACTACT GAAGGACTTG AGGATTCGTT TTCCTGGCTT TGAGCCCCTC 
ACACCCTGGA TCCTTGACCT ACTAGGCCAT TATGCTGTGA TGAACAACCC CACCAGACAG 
CCTTTGGCCC TAAACGTTGC ATACAGGCGC TGCTTGCAGA TTCTGGCTGC AGGACTGTTC 
CTGCCAGGTT CAGTGGGTAT CACTGACCCC TGTGAGAGTG GCAACTTTAG AGTACACACA 
GTCATGACCC TAGAACAGCA GGACATGGTC TGCTATACAG CTCAGACTCT CGTCCGAATC 
CTCTCACATG GTGGCTTTAG GAAGATCCTT GGCCAGGAGG GTGATGCCAG CTATCTTGCT 
TCTGAAATAT CTACCTGGGA TGGAGTGATA GTAACACCTT CAGAAAAGGC TTATGAGAAG 
CCACCAGAGA AGAAGGAAGG AGAGGAAGAA GAGGAGAATA CAGAAGAACC ACCTCAAGGA 
GAGGAAGAAG AAAGCATGGA AACTCAGGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma.
Cancer cell32(1)88-100.e6(2017 Jul)
Marchesini M,Ogoti Y,Fiorini E,Aktas Samur A,Nezi L,D'Anca M,Storti P,Samur MK,Ganan-Gomez I,Fulciniti MT,Mistry N,Jiang S,Bao N,Marchica V,Neri A,Bueso-Ramos C,Wu CJ,Zhang L,Liang H,Peng X,Giuliani N,Draetta G,Clise-Dwyer K,Kantarjian H,Munshi N,Orlowski R,Garcia-Manero G,DePinho RA,Colla S

Expression and Clinical Significance of ILF2 in Gastric Cancer.
Disease markers20174387081(2017)
Yin ZH,Jiang XW,Shi WB,Gui QL,Yu DF

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

ILF2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報