TMPRSS9 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMPRSS9
Entrez Gene ID	360200
Full Name	transmembrane serine protease 9
General protein information	Preferred Names transmembrane serine protease 9 Names transmembrane protease serine 9 polyserase-1 polyserase-I polyserine protease 1 transmembrane protease, serine 9
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Summary	The protein encoded by this gene is a membrane-bound type II serine polyprotease that is cleaved to release three different proteases. Two of the proteases are active and can be inhibited by serine protease inhibitors, and one is thought to be catalytically inactive. This gene enhances the invasive capability of pancreatic cancer cells and may be involved in cancer progression. [provided by RefSeq, Jul 2016].
Disorder MIM:	610477

mRNA and Protein(s)

mRNA	Protein	Name
XM_011527978.2	XP_011526280.1	transmembrane protease serine 9 isoform X1
NM_182973.2	NP_892018.1	transmembrane protease serine 9
XM_011527982.2	XP_011526284.1	transmembrane protease serine 9 isoform X3
XM_011527982.3	XP_011526284.1	transmembrane protease serine 9 isoform X3
XM_011527980.1	XP_011526282.1	transmembrane protease serine 9 isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TMPRSS9	XP_005633295.1
Bos taurus (cattle)	TMPRSS9	XP_002688999.1
Mus musculus (house mouse)	Tmprss9	NP_001075157.2
Rattus norvegicus (Norway rat)	Tmprss9	NP_001040565.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010659	XP_311380.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010615	XP_001237581.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001244	XP_321898.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001252	XP_321900.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010619	XP_001230717.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010692	XP_311408.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010663	XP_559166.1
Homo sapiens (human)	TMPRSS9	NP_892018.1
	TMPRSS9	XP_002801062.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012470	XP_001230511.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012670	XP_307656.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001251	XP_001689373.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001241	XP_321913.5
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010618	XP_001688265.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012491	XP_001230277.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010015	XP_001238092.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010614	XP_001237580.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001249	XP_001689375.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001246	XP_321901.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001245	XP_001689377.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012692	XP_307636.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010617	XP_001230715.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012492	XP_001230278.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010661	XP_311381.4
Pan troglodytes (chimpanzee)	TMPRSS9	XP_003316043.2
Gallus gallus (chicken)	TMPRSS9	XP_425880.4
Danio rerio (zebrafish)	tmprss9	XP_001922711.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001248	XP_001238557.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001247	XP_001689376.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012566	XP_001230550.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010620	XP_001230718.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012473	XP_307308.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006869	XP_308888.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001250	XP_001689374.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012671	XP_001230557.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012472	XP_001687805.1
Xenopus tropicalis (tropical clawed frog)	tmprss9	XP_002940084.2

Gene Ontology
Bibliography

Related articles in PubMed

Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA.
Fontanil T, Mohamedi Y, Esteban MM, Obaya AJ, Cal S
Oncology reports31(6)2792-6(2014 Jun)

TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.
Aragam N, Wang KS, Anderson JL, Liu X
Journal of molecular neuroscience : MN50(2)250-6(2013 Jun)

Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycans.
Okumura Y, Hayama M, Takahashi E, Fujiuchi M, Shimabukuro A, Yano M, Kido H
The Biochemical journal400(3)551-61(2006 Dec)

Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product.
Cal S, Quesada V, Garabaya C, Lopez-Otin C
Proceedings of the National Academy of Sciences of the United States of America100(16)9185-90(2003 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These effects were mediated by the efficient conversion of pro-uPA to active uPA and high phosphorylation levels of ERK detected in the PANC-1 cells expressing exogenous polyserase-1.
Title: Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA.

SNP rs4806846 in TMPRSS9 gene is associated with neuroticism in a European sample.
Title: TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The isolation and characterization of serase-1B, a splice variant of polyserase-1, is reported (accession AB109390.1).
Title: Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycans.

Polyserase-I is a human polyprotease with the ability to generate independent serine protease domains from a single translation product
Title: Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product.

The following TMPRSS9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMPRSS9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu79584	XM_011527982.3 Latest version!	Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu79582	XM_011527980.1 Latest version!	Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu02342	NM_182973.2 Latest version!	Homo sapiens transmembrane serine protease 9 (TMPRSS9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$748.30 $1069.00
OHu51580	XM_011527978.2 Latest version!	Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu79584	XM_011527982.2	Homo sapiens transmembrane protease, serine 9 (TMPRSS9), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMPRSS9 ( XM_011527982.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526284.1 Homo sapiens transmembrane protease, serine 9 (TMPRSS9), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu79584
Clone ID Related Accession (Same CDS sequence)	XM_011527982.2 , XM_011527982.3
Accession Version	XM_011527982.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1689bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	transmembrane protease serine 9 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527982.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGC CCACCCGGGT CGTGGGCGGG TTCGGAGCTG CCTCCGGGGA GGTGCCCTGG 
CAGGTCAGCC TGAAGGAAGG GTCCCGGCAC TTCTGCGGAG CAACTGTGGT GGGGGACCGC 
TGGCTGCTGT CTGCCGCCCA CTGCTTCAAC CACACGAAGG TGGAGCAGGT TCGGGCCCAC 
CTGGGCACTG CGTCCCTCCT GGGCCTGGGC GGGAGCCCGG TGAAGATCGG GCTGCGGCGG 
GTAGTGCTGC ACCCCCTCTA CAACCCTGGC ATCCTGGACT TCGACCTGGC TGTCCTGGAG 
CTGGCCAGCC CCCTGGCCTT CAACAAATAC ATCCAGCCTG TCTGCCTGCC CCTGGCCATC 
CAGAAGTTCC CTGTGGGCCG GAAGTGCATG ATCTCCGGAT GGGGAAATAC GCAGGAAGGA 
AATGCCACCA AGCCCGAGCT CCTGCAGAAG GCGTCCGTGG GCATCATAGA CCAGAAAACC 
TGTAGTGTGC TCTACAACTT CTCCCTCACA GACCGCATGA TCTGCGCAGG CTTCCTGGAA 
GGCAAAGTCG ACTCCTGCCA GGGTGACTCT GGGGGCCCCC TGGCCTGCGA GGAGGCCCCT 
GGCGTGTTTT ATCTGGCAGG GATCGTGAGC TGGGGTATTG GCTGCGCTCA GGTTAAGAAG 
CCGGGCGTGT ACACGCGCAT CACCAGGCTA AAGGGCTGGA TCCTGGAGAT CATGTCCTCC 
CAGCCCCTTC CCATGTCTCC CCCCTCGACC ACAAGGATGC TGGCCACCAC CAGCCCCAGG 
ACGACAGCTG GCCTCACAGT CCCGGGGGCC ACACCCAGCA GACCCACCCC TGGGGCTGCC 
AGCAGGGTGA CGGGCCAACC TGCCAACTCA ACCTTATCTG CCGTGAGCAC CACTGCTAGG 
GGACAGACGC CATTTCCAGA CGCCCCGGAG GCCACCACAC ACACCCAGCT ACCAGACTGT 
GGCCTGGCGC CGGCCGCGCT CACCAGGATT GTGGGCGGCA GCGCAGCGGG CCGTGGGGAG 
TGGCCGTGGC AGGTGAGCCT GTGGCTGCGG CGCCGGGAAC ACCGTTGCGG GGCCGTGCTG 
GTGGCAGAGA GGTGGCTGCT GTCGGCGGCG CACTGCTTCG ACGTCTACGG GGACCCCAAG 
CAGTGGGCGG CCTTCCTAGG CACGCCGTTC CTGAGCGGCG CGGAGGGGCA GCTGGAGCGC 
GTGGCGCGCA TCTACAAGCA CCCGTTCTAC AATCTCTACA CGCTCGACTA CGACGTGGCG 
CTGCTGGAGC TGGCGGGGCC GGTGCGTCGC AGCCGCCTGG TGCGTCCCAT CTGCCTGCCC 
GAGCCCGCGC CGCGACCCCC GGACGGCACG CGCTGCGTCA TCACCGGCTG GGGCTCGGTG 
CGCGAAGGAG GCTCCATGGC GCGGCAGCTG CAGAAGGCGG CCGTGCGCCT CCTCAGCGAG 
CAGACCTGCC GCCGCTTCTA CCCAGTGCAG ATCAGCAGCC GCATGCTGTG TGCCGGCTTC 
CCGCAGGGTG GCGTGGACAG CTGCTCGGGT GACGCTGGGG GACCCCTGGC CTGCAGGGAG 
CCCTCTGGAC GGTGGGTGCT AACTGGGGTC ACTAGCTGGG GCTATGGCTG TGGCCGGCCC 
CACTTCCCAG GTGTCTATAC CCGGGTGGCA GCTGTGAGAG GCTGGATAGG ACAGCACATC 
CAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526284.1
CDS	286..1974
Translation	MEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE

Target ORF information:

RefSeq Version	XM_011527982.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protease, serine 9 (TMPRSS9), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527982.2

ORF Insert Sequence:

ATGGAGAAGC CCACCCGGGT CGTGGGCGGG TTCGGAGCTG CCTCCGGGGA GGTGCCCTGG 
CAGGTCAGCC TGAAGGAAGG GTCCCGGCAC TTCTGCGGAG CAACTGTGGT GGGGGACCGC 
TGGCTGCTGT CTGCCGCCCA CTGCTTCAAC CACACGAAGG TGGAGCAGGT TCGGGCCCAC 
CTGGGCACTG CGTCCCTCCT GGGCCTGGGC GGGAGCCCGG TGAAGATCGG GCTGCGGCGG 
GTAGTGCTGC ACCCCCTCTA CAACCCTGGC ATCCTGGACT TCGACCTGGC TGTCCTGGAG 
CTGGCCAGCC CCCTGGCCTT CAACAAATAC ATCCAGCCTG TCTGCCTGCC CCTGGCCATC 
CAGAAGTTCC CTGTGGGCCG GAAGTGCATG ATCTCCGGAT GGGGAAATAC GCAGGAAGGA 
AATGCCACCA AGCCCGAGCT CCTGCAGAAG GCGTCCGTGG GCATCATAGA CCAGAAAACC 
TGTAGTGTGC TCTACAACTT CTCCCTCACA GACCGCATGA TCTGCGCAGG CTTCCTGGAA 
GGCAAAGTCG ACTCCTGCCA GGGTGACTCT GGGGGCCCCC TGGCCTGCGA GGAGGCCCCT 
GGCGTGTTTT ATCTGGCAGG GATCGTGAGC TGGGGTATTG GCTGCGCTCA GGTTAAGAAG 
CCGGGCGTGT ACACGCGCAT CACCAGGCTA AAGGGCTGGA TCCTGGAGAT CATGTCCTCC 
CAGCCCCTTC CCATGTCTCC CCCCTCGACC ACAAGGATGC TGGCCACCAC CAGCCCCAGG 
ACGACAGCTG GCCTCACAGT CCCGGGGGCC ACACCCAGCA GACCCACCCC TGGGGCTGCC 
AGCAGGGTGA CGGGCCAACC TGCCAACTCA ACCTTATCTG CCGTGAGCAC CACTGCTAGG 
GGACAGACGC CATTTCCAGA CGCCCCGGAG GCCACCACAC ACACCCAGCT ACCAGACTGT 
GGCCTGGCGC CGGCCGCGCT CACCAGGATT GTGGGCGGCA GCGCAGCGGG CCGTGGGGAG 
TGGCCGTGGC AGGTGAGCCT GTGGCTGCGG CGCCGGGAAC ACCGTTGCGG GGCCGTGCTG 
GTGGCAGAGA GGTGGCTGCT GTCGGCGGCG CACTGCTTCG ACGTCTACGG GGACCCCAAG 
CAGTGGGCGG CCTTCCTAGG CACGCCGTTC CTGAGCGGCG CGGAGGGGCA GCTGGAGCGC 
GTGGCGCGCA TCTACAAGCA CCCGTTCTAC AATCTCTACA CGCTCGACTA CGACGTGGCG 
CTGCTGGAGC TGGCGGGGCC GGTGCGTCGC AGCCGCCTGG TGCGTCCCAT CTGCCTGCCC 
GAGCCCGCGC CGCGACCCCC GGACGGCACG CGCTGCGTCA TCACCGGCTG GGGCTCGGTG 
CGCGAAGGAG GCTCCATGGC GCGGCAGCTG CAGAAGGCGG CCGTGCGCCT CCTCAGCGAG 
CAGACCTGCC GCCGCTTCTA CCCAGTGCAG ATCAGCAGCC GCATGCTGTG TGCCGGCTTC 
CCGCAGGGTG GCGTGGACAG CTGCTCGGGT GACGCTGGGG GACCCCTGGC CTGCAGGGAG 
CCCTCTGGAC GGTGGGTGCT AACTGGGGTC ACTAGCTGGG GCTATGGCTG TGGCCGGCCC 
CACTTCCCAG GTGTCTATAC CCGGGTGGCA GCTGTGAGAG GCTGGATAGG ACAGCACATC 
CAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS9 ( XM_011527982.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526284.1 Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu79584
Clone ID Related Accession (Same CDS sequence)	XM_011527982.2 , XM_011527982.3
Accession Version	XM_011527982.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1689bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protease serine 9 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011527982.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGC CCACCCGGGT CGTGGGCGGG TTCGGAGCTG CCTCCGGGGA GGTGCCCTGG 
CAGGTCAGCC TGAAGGAAGG GTCCCGGCAC TTCTGCGGAG CAACTGTGGT GGGGGACCGC 
TGGCTGCTGT CTGCCGCCCA CTGCTTCAAC CACACGAAGG TGGAGCAGGT TCGGGCCCAC 
CTGGGCACTG CGTCCCTCCT GGGCCTGGGC GGGAGCCCGG TGAAGATCGG GCTGCGGCGG 
GTAGTGCTGC ACCCCCTCTA CAACCCTGGC ATCCTGGACT TCGACCTGGC TGTCCTGGAG 
CTGGCCAGCC CCCTGGCCTT CAACAAATAC ATCCAGCCTG TCTGCCTGCC CCTGGCCATC 
CAGAAGTTCC CTGTGGGCCG GAAGTGCATG ATCTCCGGAT GGGGAAATAC GCAGGAAGGA 
AATGCCACCA AGCCCGAGCT CCTGCAGAAG GCGTCCGTGG GCATCATAGA CCAGAAAACC 
TGTAGTGTGC TCTACAACTT CTCCCTCACA GACCGCATGA TCTGCGCAGG CTTCCTGGAA 
GGCAAAGTCG ACTCCTGCCA GGGTGACTCT GGGGGCCCCC TGGCCTGCGA GGAGGCCCCT 
GGCGTGTTTT ATCTGGCAGG GATCGTGAGC TGGGGTATTG GCTGCGCTCA GGTTAAGAAG 
CCGGGCGTGT ACACGCGCAT CACCAGGCTA AAGGGCTGGA TCCTGGAGAT CATGTCCTCC 
CAGCCCCTTC CCATGTCTCC CCCCTCGACC ACAAGGATGC TGGCCACCAC CAGCCCCAGG 
ACGACAGCTG GCCTCACAGT CCCGGGGGCC ACACCCAGCA GACCCACCCC TGGGGCTGCC 
AGCAGGGTGA CGGGCCAACC TGCCAACTCA ACCTTATCTG CCGTGAGCAC CACTGCTAGG 
GGACAGACGC CATTTCCAGA CGCCCCGGAG GCCACCACAC ACACCCAGCT ACCAGACTGT 
GGCCTGGCGC CGGCCGCGCT CACCAGGATT GTGGGCGGCA GCGCAGCGGG CCGTGGGGAG 
TGGCCGTGGC AGGTGAGCCT GTGGCTGCGG CGCCGGGAAC ACCGTTGCGG GGCCGTGCTG 
GTGGCAGAGA GGTGGCTGCT GTCGGCGGCG CACTGCTTCG ACGTCTACGG GGACCCCAAG 
CAGTGGGCGG CCTTCCTAGG CACGCCGTTC CTGAGCGGCG CGGAGGGGCA GCTGGAGCGC 
GTGGCGCGCA TCTACAAGCA CCCGTTCTAC AATCTCTACA CGCTCGACTA CGACGTGGCG 
CTGCTGGAGC TGGCGGGGCC GGTGCGTCGC AGCCGCCTGG TGCGTCCCAT CTGCCTGCCC 
GAGCCCGCGC CGCGACCCCC GGACGGCACG CGCTGCGTCA TCACCGGCTG GGGCTCGGTG 
CGCGAAGGAG GCTCCATGGC GCGGCAGCTG CAGAAGGCGG CCGTGCGCCT CCTCAGCGAG 
CAGACCTGCC GCCGCTTCTA CCCAGTGCAG ATCAGCAGCC GCATGCTGTG TGCCGGCTTC 
CCGCAGGGTG GCGTGGACAG CTGCTCGGGT GACGCTGGGG GACCCCTGGC CTGCAGGGAG 
CCCTCTGGAC GGTGGGTGCT AACTGGGGTC ACTAGCTGGG GCTATGGCTG TGGCCGGCCC 
CACTTCCCAG GTGTCTATAC CCGGGTGGCA GCTGTGAGAG GCTGGATAGG ACAGCACATC 
CAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526284.1
CDS	297..1985
Translation	MEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE

Target ORF information:

RefSeq Version	XM_011527982.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527982.3

ORF Insert Sequence:

ATGGAGAAGC CCACCCGGGT CGTGGGCGGG TTCGGAGCTG CCTCCGGGGA GGTGCCCTGG 
CAGGTCAGCC TGAAGGAAGG GTCCCGGCAC TTCTGCGGAG CAACTGTGGT GGGGGACCGC 
TGGCTGCTGT CTGCCGCCCA CTGCTTCAAC CACACGAAGG TGGAGCAGGT TCGGGCCCAC 
CTGGGCACTG CGTCCCTCCT GGGCCTGGGC GGGAGCCCGG TGAAGATCGG GCTGCGGCGG 
GTAGTGCTGC ACCCCCTCTA CAACCCTGGC ATCCTGGACT TCGACCTGGC TGTCCTGGAG 
CTGGCCAGCC CCCTGGCCTT CAACAAATAC ATCCAGCCTG TCTGCCTGCC CCTGGCCATC 
CAGAAGTTCC CTGTGGGCCG GAAGTGCATG ATCTCCGGAT GGGGAAATAC GCAGGAAGGA 
AATGCCACCA AGCCCGAGCT CCTGCAGAAG GCGTCCGTGG GCATCATAGA CCAGAAAACC 
TGTAGTGTGC TCTACAACTT CTCCCTCACA GACCGCATGA TCTGCGCAGG CTTCCTGGAA 
GGCAAAGTCG ACTCCTGCCA GGGTGACTCT GGGGGCCCCC TGGCCTGCGA GGAGGCCCCT 
GGCGTGTTTT ATCTGGCAGG GATCGTGAGC TGGGGTATTG GCTGCGCTCA GGTTAAGAAG 
CCGGGCGTGT ACACGCGCAT CACCAGGCTA AAGGGCTGGA TCCTGGAGAT CATGTCCTCC 
CAGCCCCTTC CCATGTCTCC CCCCTCGACC ACAAGGATGC TGGCCACCAC CAGCCCCAGG 
ACGACAGCTG GCCTCACAGT CCCGGGGGCC ACACCCAGCA GACCCACCCC TGGGGCTGCC 
AGCAGGGTGA CGGGCCAACC TGCCAACTCA ACCTTATCTG CCGTGAGCAC CACTGCTAGG 
GGACAGACGC CATTTCCAGA CGCCCCGGAG GCCACCACAC ACACCCAGCT ACCAGACTGT 
GGCCTGGCGC CGGCCGCGCT CACCAGGATT GTGGGCGGCA GCGCAGCGGG CCGTGGGGAG 
TGGCCGTGGC AGGTGAGCCT GTGGCTGCGG CGCCGGGAAC ACCGTTGCGG GGCCGTGCTG 
GTGGCAGAGA GGTGGCTGCT GTCGGCGGCG CACTGCTTCG ACGTCTACGG GGACCCCAAG 
CAGTGGGCGG CCTTCCTAGG CACGCCGTTC CTGAGCGGCG CGGAGGGGCA GCTGGAGCGC 
GTGGCGCGCA TCTACAAGCA CCCGTTCTAC AATCTCTACA CGCTCGACTA CGACGTGGCG 
CTGCTGGAGC TGGCGGGGCC GGTGCGTCGC AGCCGCCTGG TGCGTCCCAT CTGCCTGCCC 
GAGCCCGCGC CGCGACCCCC GGACGGCACG CGCTGCGTCA TCACCGGCTG GGGCTCGGTG 
CGCGAAGGAG GCTCCATGGC GCGGCAGCTG CAGAAGGCGG CCGTGCGCCT CCTCAGCGAG 
CAGACCTGCC GCCGCTTCTA CCCAGTGCAG ATCAGCAGCC GCATGCTGTG TGCCGGCTTC 
CCGCAGGGTG GCGTGGACAG CTGCTCGGGT GACGCTGGGG GACCCCTGGC CTGCAGGGAG 
CCCTCTGGAC GGTGGGTGCT AACTGGGGTC ACTAGCTGGG GCTATGGCTG TGGCCGGCCC 
CACTTCCCAG GTGTCTATAC CCGGGTGGCA GCTGTGAGAG GCTGGATAGG ACAGCACATC 
CAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS9 ( XM_011527980.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526282.1 Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X2, mRNA.

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CloneID	OHu79582
Clone ID Related Accession (Same CDS sequence)	XM_011527980.1
Accession Version	XM_011527980.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2073bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protease serine 9 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTGCG CTGGCTACCT GGACGGGAAG GTGGACTCCT GCCAGGGTGA CTCAGGAGGA 
CCCCTGGTCT GCGAGGAGCC CTCTGGCCGG TTCTTTCTGG CTGGCATCGT GAGCTGGGGA 
ATCGGGTGTG CGGAAGCCCG GCGTCCAGGG GTCTATGCCC GAGTCACCAG GCTACGTGAC 
TGGATCCTGG AGGCCACCAC CAAAGCCAGC ATGCCTCTGG CCCCCACCAT GGCTCCTGCC 
CCTGCCGCCC CCAGCACAGC CTGGCCCACC AGTCCTGAGA GCCCTGTGGT CAGCACCCCC 
ACCAAATCGA TGCAGGCCCT CAGTACCGTG CCTCTTGACT GGGTCACCGT TCCTAAGCTA 
CAAGAATGTG GGGCCAGGCC TGCAATGGAG AAGCCCACCC GGGTCGTGGG CGGGTTCGGA 
GCTGCCTCCG GGGAGGTGCC CTGGCAGGTC AGCCTGAAGG AAGGGTCCCG GCACTTCTGC 
GGAGCAACTG TGGTGGGGGA CCGCTGGCTG CTGTCTGCCG CCCACTGCTT CAACCACACG 
AAGGTGGAGC AGGTTCGGGC CCACCTGGGC ACTGCGTCCC TCCTGGGCCT GGGCGGGAGC 
CCGGTGAAGA TCGGGCTGCG GCGGGTAGTG CTGCACCCCC TCTACAACCC TGGCATCCTG 
GACTTCGACC TGGCTGTCCT GGAGCTGGCC AGCCCCCTGG CCTTCAACAA ATACATCCAG 
CCTGTCTGCC TGCCCCTGGC CATCCAGAAG TTCCCTGTGG GCCGGAAGTG CATGATCTCC 
GGATGGGGAA ATACGCAGGA AGGAAATGCC ACCAAGCCCG AGCTCCTGCA GAAGGCGTCC 
GTGGGCATCA TAGACCAGAA AACCTGTAGT GTGCTCTACA ACTTCTCCCT CACAGACCGC 
ATGATCTGCG CAGGCTTCCT GGAAGGCAAA GTCGACTCCT GCCAGGGTGA CTCTGGGGGC 
CCCCTGGCCT GCGAGGAGGC CCCTGGCGTG TTTTATCTGG CAGGGATCGT GAGCTGGGGT 
ATTGGCTGCG CTCAGGTTAA GAAGCCGGGC GTGTACACGC GCATCACCAG GCTAAAGGGC 
TGGATCCTGG AGATCATGTC CTCCCAGCCC CTTCCCATGT CTCCCCCCTC GACCACAAGG 
ATGCTGGCCA CCACCAGCCC CAGGACGACA GCTGGCCTCA CAGTCCCGGG GGCCACACCC 
AGCAGACCCA CCCCTGGGGC TGCCAGCAGG GTGACGGGCC AACCTGCCAA CTCAACCTTA 
TCTGCCGTGA GCACCACTGC TAGGGGACAG ACGCCATTTC CAGACGCCCC GGAGGCCACC 
ACACACACCC AGCTACCAGA CTGTGGCCTG GCGCCGGCCG CGCTCACCAG GATTGTGGGC 
GGCAGCGCAG CGGGCCGTGG GGAGTGGCCG TGGCAGGTGA GCCTGTGGCT GCGGCGCCGG 
GAACACCGTT GCGGGGCCGT GCTGGTGGCA GAGAGGTGGC TGCTGTCGGC GGCGCACTGC 
TTCGACGTCT ACGGGGACCC CAAGCAGTGG GCGGCCTTCC TAGGCACGCC GTTCCTGAGC 
GGCGCGGAGG GGCAGCTGGA GCGCGTGGCG CGCATCTACA AGCACCCGTT CTACAATCTC 
TACACGCTCG ACTACGACGT GGCGCTGCTG GAGCTGGCGG GGCCGGTGCG TCGCAGCCGC 
CTGGTGCGTC CCATCTGCCT GCCCGAGCCC GCGCCGCGAC CCCCGGACGG CACGCGCTGC 
GTCATCACCG GCTGGGGCTC GGTGCGCGAA GGAGGCTCCA TGGCGCGGCA GCTGCAGAAG 
GCGGCCGTGC GCCTCCTCAG CGAGCAGACC TGCCGCCGCT TCTACCCAGT GCAGATCAGC 
AGCCGCATGC TGTGTGCCGG CTTCCCGCAG GGTGGCGTGG ACAGCTGCTC GGGTGACGCT 
GGGGGACCCC TGGCCTGCAG GGAGCCCTCT GGACGGTGGG TGCTAACTGG GGTCACTAGC 
TGGGGCTATG GCTGTGGCCG GCCCCACTTC CCAGGTGTCT ATACCCGGGT GGCAGCTGTG 
AGAGGCTGGA TAGGACAGCA CATCCAGGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526282.1
CDS	127..2199
Translation	MVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE

Target ORF information:

RefSeq Version	XM_011527980.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527980.1

ORF Insert Sequence:

ATGGTGTGCG CTGGCTACCT GGACGGGAAG GTGGACTCCT GCCAGGGTGA CTCAGGAGGA 
CCCCTGGTCT GCGAGGAGCC CTCTGGCCGG TTCTTTCTGG CTGGCATCGT GAGCTGGGGA 
ATCGGGTGTG CGGAAGCCCG GCGTCCAGGG GTCTATGCCC GAGTCACCAG GCTACGTGAC 
TGGATCCTGG AGGCCACCAC CAAAGCCAGC ATGCCTCTGG CCCCCACCAT GGCTCCTGCC 
CCTGCCGCCC CCAGCACAGC CTGGCCCACC AGTCCTGAGA GCCCTGTGGT CAGCACCCCC 
ACCAAATCGA TGCAGGCCCT CAGTACCGTG CCTCTTGACT GGGTCACCGT TCCTAAGCTA 
CAAGAATGTG GGGCCAGGCC TGCAATGGAG AAGCCCACCC GGGTCGTGGG CGGGTTCGGA 
GCTGCCTCCG GGGAGGTGCC CTGGCAGGTC AGCCTGAAGG AAGGGTCCCG GCACTTCTGC 
GGAGCAACTG TGGTGGGGGA CCGCTGGCTG CTGTCTGCCG CCCACTGCTT CAACCACACG 
AAGGTGGAGC AGGTTCGGGC CCACCTGGGC ACTGCGTCCC TCCTGGGCCT GGGCGGGAGC 
CCGGTGAAGA TCGGGCTGCG GCGGGTAGTG CTGCACCCCC TCTACAACCC TGGCATCCTG 
GACTTCGACC TGGCTGTCCT GGAGCTGGCC AGCCCCCTGG CCTTCAACAA ATACATCCAG 
CCTGTCTGCC TGCCCCTGGC CATCCAGAAG TTCCCTGTGG GCCGGAAGTG CATGATCTCC 
GGATGGGGAA ATACGCAGGA AGGAAATGCC ACCAAGCCCG AGCTCCTGCA GAAGGCGTCC 
GTGGGCATCA TAGACCAGAA AACCTGTAGT GTGCTCTACA ACTTCTCCCT CACAGACCGC 
ATGATCTGCG CAGGCTTCCT GGAAGGCAAA GTCGACTCCT GCCAGGGTGA CTCTGGGGGC 
CCCCTGGCCT GCGAGGAGGC CCCTGGCGTG TTTTATCTGG CAGGGATCGT GAGCTGGGGT 
ATTGGCTGCG CTCAGGTTAA GAAGCCGGGC GTGTACACGC GCATCACCAG GCTAAAGGGC 
TGGATCCTGG AGATCATGTC CTCCCAGCCC CTTCCCATGT CTCCCCCCTC GACCACAAGG 
ATGCTGGCCA CCACCAGCCC CAGGACGACA GCTGGCCTCA CAGTCCCGGG GGCCACACCC 
AGCAGACCCA CCCCTGGGGC TGCCAGCAGG GTGACGGGCC AACCTGCCAA CTCAACCTTA 
TCTGCCGTGA GCACCACTGC TAGGGGACAG ACGCCATTTC CAGACGCCCC GGAGGCCACC 
ACACACACCC AGCTACCAGA CTGTGGCCTG GCGCCGGCCG CGCTCACCAG GATTGTGGGC 
GGCAGCGCAG CGGGCCGTGG GGAGTGGCCG TGGCAGGTGA GCCTGTGGCT GCGGCGCCGG 
GAACACCGTT GCGGGGCCGT GCTGGTGGCA GAGAGGTGGC TGCTGTCGGC GGCGCACTGC 
TTCGACGTCT ACGGGGACCC CAAGCAGTGG GCGGCCTTCC TAGGCACGCC GTTCCTGAGC 
GGCGCGGAGG GGCAGCTGGA GCGCGTGGCG CGCATCTACA AGCACCCGTT CTACAATCTC 
TACACGCTCG ACTACGACGT GGCGCTGCTG GAGCTGGCGG GGCCGGTGCG TCGCAGCCGC 
CTGGTGCGTC CCATCTGCCT GCCCGAGCCC GCGCCGCGAC CCCCGGACGG CACGCGCTGC 
GTCATCACCG GCTGGGGCTC GGTGCGCGAA GGAGGCTCCA TGGCGCGGCA GCTGCAGAAG 
GCGGCCGTGC GCCTCCTCAG CGAGCAGACC TGCCGCCGCT TCTACCCAGT GCAGATCAGC 
AGCCGCATGC TGTGTGCCGG CTTCCCGCAG GGTGGCGTGG ACAGCTGCTC GGGTGACGCT 
GGGGGACCCC TGGCCTGCAG GGAGCCCTCT GGACGGTGGG TGCTAACTGG GGTCACTAGC 
TGGGGCTATG GCTGTGGCCG GCCCCACTTC CCAGGTGTCT ATACCCGGGT GGCAGCTGTG 
AGAGGCTGGA TAGGACAGCA CATCCAGGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS9 ( NM_182973.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_892018.1 Homo sapiens transmembrane serine protease 9 (TMPRSS9), mRNA.

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CloneID	OHu02342
Clone ID Related Accession (Same CDS sequence)	NM_182973.2
Accession Version	NM_182973.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	transmembrane protease serine 9
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB109390.1, AJ488946.1 and AC011522.8. On Jul 29, 2016 this sequence version replaced NM_182973.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AJ488946.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2142670, SAMEA2148874 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCCA CTGTGGCTGA CGTACACCTC GTGCCCAGGA CAACCAAGGA AGTCCCCGCT 
CTGGATGCCG CGTGCTGTCG AGCGGCCAGC ATTGGCGTGG TGGCCACCAG CCTTGTCGTC 
CTCACCCTGG GAGTCCTTTT GGCCTTCCTC TCTACACAGG GCTTCCACGT GGACCACACG 
GCCGAGCTGC GGGGAATCCG GTGGACCAGC AGTTTGCGGC GGGAGACCTC GGACTATCAC 
CGCACGCTGA CGCCCACCCT GGAGGCACTG CTGCACTTTC TGCTGCGACC CCTCCAGACG 
CTGAGCCTGG GCCTGGAGGA GGAGCTATTG CAGCGAGGGA TCCGGGCAAG GCTGCGGGAG 
CACGGCATCT CCCTGGCTGC CTATGGCACA ATTGTGTCGG CTGAGCTCAC AGGGAGACAT 
AAGGGACCCT TGGCAGAAAG AGACTTCAAA TCAGGCCGCT GTCCAGGGAA CTCCTTTTCC 
TGCGGGAACA GCCAGTGTGT GACCAAGGTG AACCCGGAGT GTGACGACCA GGAGGACTGC 
TCCGATGGGT CCGACGAGGC GCACTGCGAG TGTGGCTTGC AGCCTGCCTG GAGGATGGCC 
GGCAGGATCG TGGGCGGCAT GGAAGCATCC CCGGGGGAGT TTCCGTGGCA AGCCAGCCTT 
CGAGAGAACA AGGAGCACTT CTGTGGGGCC GCCATCATCA ACGCCAGGTG GCTGGTGTCT 
GCTGCTCACT GCTTCAATGA GTTCCAAGAC CCGACGAAGT GGGTGGCCTA CGTGGGTGCG 
ACCTACCTCA GCGGCTCGGA GGCCAGCACC GTGCGGGCCC AGGTGGTCCA GATCGTCAAG 
CACCCCCTGT ACAACGCGGA CACGGCCGAC TTTGACGTGG CTGTGCTGGA GCTGACCAGC 
CCTCTGCCTT TCGGCCGGCA CATCCAGCCC GTGTGCCTCC CGGCTGCCAC ACACATCTTC 
CCACCCAGCA AGAAGTGCCT GATCTCAGGC TGGGGCTACC TCAAGGAGGA CTTCCTGGTC 
AAGCCAGAGG TGCTGCAGAA AGCCACTGTG GAGCTGCTGG ACCAGGCACT GTGTGCCAGC 
TTGTACGGCC ATTCACTCAC TGACAGGATG GTGTGCGCTG GCTACCTGGA CGGGAAGGTG 
GACTCCTGCC AGGGTGACTC AGGAGGACCC CTGGTCTGCG AGGAGCCCTC TGGCCGGTTC 
TTTCTGGCTG GCATCGTGAG CTGGGGAATC GGGTGTGCGG AAGCCCGGCG TCCAGGGGTC 
TATGCCCGAG TCACCAGGCT ACGTGACTGG ATCCTGGAGG CCACCACCAA AGCCAGCATG 
CCTCTGGCCC CCACCATGGC TCCTGCCCCT GCCGCCCCCA GCACAGCCTG GCCCACCAGT 
CCTGAGAGCC CTGTGGTCAG CACCCCCACC AAATCGATGC AGGCCCTCAG TACCGTGCCT 
CTTGACTGGG TCACCGTTCC TAAGCTACAA GAATGTGGGG CCAGGCCTGC AATGGAGAAG 
CCCACCCGGG TCGTGGGCGG GTTCGGAGCT GCCTCCGGGG AGGTGCCCTG GCAGGTCAGC 
CTGAAGGAAG GGTCCCGGCA CTTCTGCGGA GCAACTGTGG TGGGGGACCG CTGGCTGCTG 
TCTGCCGCCC ACTGCTTCAA CCACACGAAG GTGGAGCAGG TTCGGGCCCA CCTGGGCACT 
GCGTCCCTCC TGGGCCTGGG CGGGAGCCCG GTGAAGATCG GGCTGCGGCG GGTAGTGCTG 
CACCCCCTCT ACAACCCTGG CATCCTGGAC TTCGACCTGG CTGTCCTGGA GCTGGCCAGC 
CCCCTGGCCT TCAACAAATA CATCCAGCCT GTCTGCCTGC CCCTGGCCAT CCAGAAGTTC 
CCTGTGGGCC GGAAGTGCAT GATCTCCGGA TGGGGAAATA CGCAGGAAGG AAATGCCACC 
AAGCCCGAGC TCCTGCAGAA GGCGTCCGTG GGCATCATAG ACCAGAAAAC CTGTAGTGTG 
CTCTACAACT TCTCCCTCAC AGACCGCATG ATCTGCGCAG GCTTCCTGGA AGGCAAAGTC 
GACTCCTGCC AGGGTGACTC TGGGGGCCCC CTGGCCTGCG AGGAGGCCCC TGGCGTGTTT 
TATCTGGCAG GGATCGTGAG CTGGGGTATT GGCTGCGCTC AGGTTAAGAA GCCGGGCGTG 
TACACGCGCA TCACCAGGCT AAAGGGCTGG ATCCTGGAGA TCATGTCCTC CCAGCCCCTT 
CCCATGTCTC CCCCCTCGAC CACAAGGATG CTGGCCACCA CCAGCCCCAG GACGACAGCT 
GGCCTCACAG TCCCGGGGGC CACACCCAGC AGACCCACCC CTGGGGCTGC CAGCAGGGTG 
ACGGGCCAAC CTGCCAACTC AACCTTATCT GCCGTGAGCA CCACTGCTAG GGGACAGACG 
CCATTTCCAG ACGCCCCGGA GGCCACCACA CACACCCAGC TACCAGACTG TGGCCTGGCG 
CCGGCCGCGC TCACCAGGAT TGTGGGCGGC AGCGCAGCGG GCCGTGGGGA GTGGCCGTGG 
CAGGTGAGCC TGTGGCTGCG GCGCCGGGAA CACCGTTGCG GGGCCGTGCT GGTGGCAGAG 
AGGTGGCTGC TGTCGGCGGC GCACTGCTTC GACGTCTACG GGGACCCCAA GCAGTGGGCG 
GCCTTCCTAG GCACGCCGTT CCTGAGCGGC GCGGAGGGGC AGCTGGAGCG CGTGGCGCGC 
ATCTACAAGC ACCCGTTCTA CAATCTCTAC ACGCTCGACT ACGACGTGGC GCTGCTGGAG 
CTGGCGGGGC CGGTGCGTCG CAGCCGCCTG GTGCGTCCCA TCTGCCTGCC CGAGCCCGCG 
CCGCGACCCC CGGACGGCAC GCGCTGCGTC ATCACCGGCT GGGGCTCGGT GCGCGAAGGA 
GGCTCCATGG CGCGGCAGCT GCAGAAGGCG GCCGTGCGCC TCCTCAGCGA GCAGACCTGC 
CGCCGCTTCT ACCCAGTGCA GATCAGCAGC CGCATGCTGT GTGCCGGCTT CCCGCAGGGT 
GGCGTGGACA GCTGCTCGGG TGACGCTGGG GGACCCCTGG CCTGCAGGGA GCCCTCTGGA 
CGGTGGGTGC TAACTGGGGT CACTAGCTGG GGCTATGGCT GTGGCCGGCC CCACTTCCCA 
GGTGTCTATA CCCGGGTGGC AGCTGTGAGA GGCTGGATAG GACAGCACAT CCAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_892018.1
CDS	16..3195
Translation	MEPTVADVHLVPRTTKEVPALDAACCRAASIGVVATSLVVLTLGVLLAFLSTQGFHVDHTAELRGIRWTSSLRRETSDYHRTLTPTLEALLHFLLRPLQTLSLGLEEELLQRGIRARLREHGISLAAYGTIVSAELTGRHKGPLAERDFKSGRCPGNSFSCGNSQCVTKVNPECDDQEDCSDGSDEAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE

Target ORF information:

RefSeq Version	NM_182973.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 9 (TMPRSS9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182973.2

ORF Insert Sequence:

ATGGAGCCCA CTGTGGCTGA CGTACACCTC GTGCCCAGGA CAACCAAGGA AGTCCCCGCT 
CTGGATGCCG CGTGCTGTCG AGCGGCCAGC ATTGGCGTGG TGGCCACCAG CCTTGTCGTC 
CTCACCCTGG GAGTCCTTTT GGCCTTCCTC TCTACACAGG GCTTCCACGT GGACCACACG 
GCCGAGCTGC GGGGAATCCG GTGGACCAGC AGTTTGCGGC GGGAGACCTC GGACTATCAC 
CGCACGCTGA CGCCCACCCT GGAGGCACTG CTGCACTTTC TGCTGCGACC CCTCCAGACG 
CTGAGCCTGG GCCTGGAGGA GGAGCTATTG CAGCGAGGGA TCCGGGCAAG GCTGCGGGAG 
CACGGCATCT CCCTGGCTGC CTATGGCACA ATTGTGTCGG CTGAGCTCAC AGGGAGACAT 
AAGGGACCCT TGGCAGAAAG AGACTTCAAA TCAGGCCGCT GTCCAGGGAA CTCCTTTTCC 
TGCGGGAACA GCCAGTGTGT GACCAAGGTG AACCCGGAGT GTGACGACCA GGAGGACTGC 
TCCGATGGGT CCGACGAGGC GCACTGCGAG TGTGGCTTGC AGCCTGCCTG GAGGATGGCC 
GGCAGGATCG TGGGCGGCAT GGAAGCATCC CCGGGGGAGT TTCCGTGGCA AGCCAGCCTT 
CGAGAGAACA AGGAGCACTT CTGTGGGGCC GCCATCATCA ACGCCAGGTG GCTGGTGTCT 
GCTGCTCACT GCTTCAATGA GTTCCAAGAC CCGACGAAGT GGGTGGCCTA CGTGGGTGCG 
ACCTACCTCA GCGGCTCGGA GGCCAGCACC GTGCGGGCCC AGGTGGTCCA GATCGTCAAG 
CACCCCCTGT ACAACGCGGA CACGGCCGAC TTTGACGTGG CTGTGCTGGA GCTGACCAGC 
CCTCTGCCTT TCGGCCGGCA CATCCAGCCC GTGTGCCTCC CGGCTGCCAC ACACATCTTC 
CCACCCAGCA AGAAGTGCCT GATCTCAGGC TGGGGCTACC TCAAGGAGGA CTTCCTGGTC 
AAGCCAGAGG TGCTGCAGAA AGCCACTGTG GAGCTGCTGG ACCAGGCACT GTGTGCCAGC 
TTGTACGGCC ATTCACTCAC TGACAGGATG GTGTGCGCTG GCTACCTGGA CGGGAAGGTG 
GACTCCTGCC AGGGTGACTC AGGAGGACCC CTGGTCTGCG AGGAGCCCTC TGGCCGGTTC 
TTTCTGGCTG GCATCGTGAG CTGGGGAATC GGGTGTGCGG AAGCCCGGCG TCCAGGGGTC 
TATGCCCGAG TCACCAGGCT ACGTGACTGG ATCCTGGAGG CCACCACCAA AGCCAGCATG 
CCTCTGGCCC CCACCATGGC TCCTGCCCCT GCCGCCCCCA GCACAGCCTG GCCCACCAGT 
CCTGAGAGCC CTGTGGTCAG CACCCCCACC AAATCGATGC AGGCCCTCAG TACCGTGCCT 
CTTGACTGGG TCACCGTTCC TAAGCTACAA GAATGTGGGG CCAGGCCTGC AATGGAGAAG 
CCCACCCGGG TCGTGGGCGG GTTCGGAGCT GCCTCCGGGG AGGTGCCCTG GCAGGTCAGC 
CTGAAGGAAG GGTCCCGGCA CTTCTGCGGA GCAACTGTGG TGGGGGACCG CTGGCTGCTG 
TCTGCCGCCC ACTGCTTCAA CCACACGAAG GTGGAGCAGG TTCGGGCCCA CCTGGGCACT 
GCGTCCCTCC TGGGCCTGGG CGGGAGCCCG GTGAAGATCG GGCTGCGGCG GGTAGTGCTG 
CACCCCCTCT ACAACCCTGG CATCCTGGAC TTCGACCTGG CTGTCCTGGA GCTGGCCAGC 
CCCCTGGCCT TCAACAAATA CATCCAGCCT GTCTGCCTGC CCCTGGCCAT CCAGAAGTTC 
CCTGTGGGCC GGAAGTGCAT GATCTCCGGA TGGGGAAATA CGCAGGAAGG AAATGCCACC 
AAGCCCGAGC TCCTGCAGAA GGCGTCCGTG GGCATCATAG ACCAGAAAAC CTGTAGTGTG 
CTCTACAACT TCTCCCTCAC AGACCGCATG ATCTGCGCAG GCTTCCTGGA AGGCAAAGTC 
GACTCCTGCC AGGGTGACTC TGGGGGCCCC CTGGCCTGCG AGGAGGCCCC TGGCGTGTTT 
TATCTGGCAG GGATCGTGAG CTGGGGTATT GGCTGCGCTC AGGTTAAGAA GCCGGGCGTG 
TACACGCGCA TCACCAGGCT AAAGGGCTGG ATCCTGGAGA TCATGTCCTC CCAGCCCCTT 
CCCATGTCTC CCCCCTCGAC CACAAGGATG CTGGCCACCA CCAGCCCCAG GACGACAGCT 
GGCCTCACAG TCCCGGGGGC CACACCCAGC AGACCCACCC CTGGGGCTGC CAGCAGGGTG 
ACGGGCCAAC CTGCCAACTC AACCTTATCT GCCGTGAGCA CCACTGCTAG GGGACAGACG 
CCATTTCCAG ACGCCCCGGA GGCCACCACA CACACCCAGC TACCAGACTG TGGCCTGGCG 
CCGGCCGCGC TCACCAGGAT TGTGGGCGGC AGCGCAGCGG GCCGTGGGGA GTGGCCGTGG 
CAGGTGAGCC TGTGGCTGCG GCGCCGGGAA CACCGTTGCG GGGCCGTGCT GGTGGCAGAG 
AGGTGGCTGC TGTCGGCGGC GCACTGCTTC GACGTCTACG GGGACCCCAA GCAGTGGGCG 
GCCTTCCTAG GCACGCCGTT CCTGAGCGGC GCGGAGGGGC AGCTGGAGCG CGTGGCGCGC 
ATCTACAAGC ACCCGTTCTA CAATCTCTAC ACGCTCGACT ACGACGTGGC GCTGCTGGAG 
CTGGCGGGGC CGGTGCGTCG CAGCCGCCTG GTGCGTCCCA TCTGCCTGCC CGAGCCCGCG 
CCGCGACCCC CGGACGGCAC GCGCTGCGTC ATCACCGGCT GGGGCTCGGT GCGCGAAGGA 
GGCTCCATGG CGCGGCAGCT GCAGAAGGCG GCCGTGCGCC TCCTCAGCGA GCAGACCTGC 
CGCCGCTTCT ACCCAGTGCA GATCAGCAGC CGCATGCTGT GTGCCGGCTT CCCGCAGGGT 
GGCGTGGACA GCTGCTCGGG TGACGCTGGG GGACCCCTGG CCTGCAGGGA GCCCTCTGGA 
CGGTGGGTGC TAACTGGGGT CACTAGCTGG GGCTATGGCT GTGGCCGGCC CCACTTCCCA 
GGTGTCTATA CCCGGGTGGC AGCTGTGAGA GGCTGGATAG GACAGCACAT CCAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS9 ( XM_011527978.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526280.1 Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X1, mRNA.

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CloneID	OHu51580
Clone ID Related Accession (Same CDS sequence)	XM_011527978.2
Accession Version	XM_011527978.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3282bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protease serine 9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527978.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCCA CTGTGGCTGA CGTACACCTC GTGCCCAGGA CAACCAAGGA AGTCCCCGCT 
CTGGATGCCG CGTGCTGTCG AGCGGCCAGC ATTGGCGTGG TGGCCACCAG CCTTGTCGTC 
CTCACCCTGG GAGTCCTTTT GGCCTTCCTC TCTACACAGG GCTTCCACGT GGACCACACG 
GCCGAGCTGC GGGGAATCCG GTGGACCAGC AGTTTGCGGC GGGAGACCTC GGACTATCAC 
CGCACGCTGA CGCCCACCCT GGAGGCACTG TTTGTAAGTA GTTTTCAGAA GACAGAGTTA 
GAGGCAAGCT GCGTGGGTTG CTCGGTACTG AATTATAGGG ATGGGAACTC CAGTGTCCTC 
GTACATTTCC AGCTGCACTT TCTGCTGCGA CCCCTCCAGA CGCTGAGCCT GGGCCTGGAG 
GAGGAGCTAT TGCAGCGAGG GATCCGGGCA AGGCTGCGGG AGCACGGCAT CTCCCTGGCT 
GCCTATGGCA CAATTGTGTC GGCTGAGCTC ACAGGGAGAC ATAAGGGACC CTTGGCAGAA 
AGAGACTTCA AATCAGGCCG CTGTCCAGGG AACTCCTTTT CCTGCGGGAA CAGCCAGTGT 
GTGACCAAGG TGAACCCGGA GTGTGACGAC CAGGAGGACT GCTCCGATGG GTCCGACGAG 
GCGCACTGCG AGTGTGGCTT GCAGCCTGCC TGGAGGATGG CCGGCAGGAT CGTGGGCGGC 
ATGGAAGCAT CCCCGGGGGA GTTTCCGTGG CAAGCCAGCC TTCGAGAGAA CAAGGAGCAC 
TTCTGTGGGG CCGCCATCAT CAACGCCAGG TGGCTGGTGT CTGCTGCTCA CTGCTTCAAT 
GAGTTCCAAG ACCCGACGAA GTGGGTGGCC TACGTGGGTG CGACCTACCT CAGCGGCTCG 
GAGGCCAGCA CCGTGCGGGC CCAGGTGGTC CAGATCGTCA AGCACCCCCT GTACAACGCG 
GACACGGCCG ACTTTGACGT GGCTGTGCTG GAGCTGACCA GCCCTCTGCC TTTCGGCCGG 
CACATCCAGC CCGTGTGCCT CCCGGCTGCC ACACACATCT TCCCACCCAG CAAGAAGTGC 
CTGATCTCAG GCTGGGGCTA CCTCAAGGAG GACTTCCTGG TCAAGCCAGA GGTGCTGCAG 
AAAGCCACTG TGGAGCTGCT GGACCAGGCA CTGTGTGCCA GCTTGTACGG CCATTCACTC 
ACTGACAGGA TGGTGTGCGC TGGCTACCTG GACGGGAAGG TGGACTCCTG CCAGGGTGAC 
TCAGGAGGAC CCCTGGTCTG CGAGGAGCCC TCTGGCCGGT TCTTTCTGGC TGGCATCGTG 
AGCTGGGGAA TCGGGTGTGC GGAAGCCCGG CGTCCAGGGG TCTATGCCCG AGTCACCAGG 
CTACGTGACT GGATCCTGGA GGCCACCACC AAAGCCAGCA TGCCTCTGGC CCCCACCATG 
GCTCCTGCCC CTGCCGCCCC CAGCACAGCC TGGCCCACCA GTCCTGAGAG CCCTGTGGTC 
AGCACCCCCA CCAAATCGAT GCAGGCCCTC AGTACCGTGC CTCTTGACTG GGTCACCGTT 
CCTAAGCTAC AAGAATGTGG GGCCAGGCCT GCAATGGAGA AGCCCACCCG GGTCGTGGGC 
GGGTTCGGAG CTGCCTCCGG GGAGGTGCCC TGGCAGGTCA GCCTGAAGGA AGGGTCCCGG 
CACTTCTGCG GAGCAACTGT GGTGGGGGAC CGCTGGCTGC TGTCTGCCGC CCACTGCTTC 
AACCACACGA AGGTGGAGCA GGTTCGGGCC CACCTGGGCA CTGCGTCCCT CCTGGGCCTG 
GGCGGGAGCC CGGTGAAGAT CGGGCTGCGG CGGGTAGTGC TGCACCCCCT CTACAACCCT 
GGCATCCTGG ACTTCGACCT GGCTGTCCTG GAGCTGGCCA GCCCCCTGGC CTTCAACAAA 
TACATCCAGC CTGTCTGCCT GCCCCTGGCC ATCCAGAAGT TCCCTGTGGG CCGGAAGTGC 
ATGATCTCCG GATGGGGAAA TACGCAGGAA GGAAATGCCA CCAAGCCCGA GCTCCTGCAG 
AAGGCGTCCG TGGGCATCAT AGACCAGAAA ACCTGTAGTG TGCTCTACAA CTTCTCCCTC 
ACAGACCGCA TGATCTGCGC AGGCTTCCTG GAAGGCAAAG TCGACTCCTG CCAGGGTGAC 
TCTGGGGGCC CCCTGGCCTG CGAGGAGGCC CCTGGCGTGT TTTATCTGGC AGGGATCGTG 
AGCTGGGGTA TTGGCTGCGC TCAGGTTAAG AAGCCGGGCG TGTACACGCG CATCACCAGG 
CTAAAGGGCT GGATCCTGGA GATCATGTCC TCCCAGCCCC TTCCCATGTC TCCCCCCTCG 
ACCACAAGGA TGCTGGCCAC CACCAGCCCC AGGACGACAG CTGGCCTCAC AGTCCCGGGG 
GCCACACCCA GCAGACCCAC CCCTGGGGCT GCCAGCAGGG TGACGGGCCA ACCTGCCAAC 
TCAACCTTAT CTGCCGTGAG CACCACTGCT AGGGGACAGA CGCCATTTCC AGACGCCCCG 
GAGGCCACCA CACACACCCA GCTACCAGAC TGTGGCCTGG CGCCGGCCGC GCTCACCAGG 
ATTGTGGGCG GCAGCGCAGC GGGCCGTGGG GAGTGGCCGT GGCAGGTGAG CCTGTGGCTG 
CGGCGCCGGG AACACCGTTG CGGGGCCGTG CTGGTGGCAG AGAGGTGGCT GCTGTCGGCG 
GCGCACTGCT TCGACGTCTA CGGGGACCCC AAGCAGTGGG CGGCCTTCCT AGGCACGCCG 
TTCCTGAGCG GCGCGGAGGG GCAGCTGGAG CGCGTGGCGC GCATCTACAA GCACCCGTTC 
TACAATCTCT ACACGCTCGA CTACGACGTG GCGCTGCTGG AGCTGGCGGG GCCGGTGCGT 
CGCAGCCGCC TGGTGCGTCC CATCTGCCTG CCCGAGCCCG CGCCGCGACC CCCGGACGGC 
ACGCGCTGCG TCATCACCGG CTGGGGCTCG GTGCGCGAAG GAGGCTCCAT GGCGCGGCAG 
CTGCAGAAGG CGGCCGTGCG CCTCCTCAGC GAGCAGACCT GCCGCCGCTT CTACCCAGTG 
CAGATCAGCA GCCGCATGCT GTGTGCCGGC TTCCCGCAGG GTGGCGTGGA CAGCTGCTCG 
GGTGACGCTG GGGGACCCCT GGCCTGCAGG GAGCCCTCTG GACGGTGGGT GCTAACTGGG 
GTCACTAGCT GGGGCTATGG CTGTGGCCGG CCCCACTTCC CAGGTGTCTA TACCCGGGTG 
GCAGCTGTGA GAGGCTGGAT AGGACAGCAC ATCCAGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526280.1
CDS	262..3543
Translation	MEPTVADVHLVPRTTKEVPALDAACCRAASIGVVATSLVVLTLGVLLAFLSTQGFHVDHTAELRGIRWTSSLRRETSDYHRTLTPTLEALFVSSFQKTELEASCVGCSVLNYRDGNSSVLVHFQLHFLLRPLQTLSLGLEEELLQRGIRARLREHGISLAAYGTIVSAELTGRHKGPLAERDFKSGRCPGNSFSCGNSQCVTKVNPECDDQEDCSDGSDEAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE

Target ORF information:

RefSeq Version	XM_011527978.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 9 (TMPRSS9), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527978.2

ORF Insert Sequence:

ATGGAGCCCA CTGTGGCTGA CGTACACCTC GTGCCCAGGA CAACCAAGGA AGTCCCCGCT 
CTGGATGCCG CGTGCTGTCG AGCGGCCAGC ATTGGCGTGG TGGCCACCAG CCTTGTCGTC 
CTCACCCTGG GAGTCCTTTT GGCCTTCCTC TCTACACAGG GCTTCCACGT GGACCACACG 
GCCGAGCTGC GGGGAATCCG GTGGACCAGC AGTTTGCGGC GGGAGACCTC GGACTATCAC 
CGCACGCTGA CGCCCACCCT GGAGGCACTG TTTGTAAGTA GTTTTCAGAA GACAGAGTTA 
GAGGCAAGCT GCGTGGGTTG CTCGGTACTG AATTATAGGG ATGGGAACTC CAGTGTCCTC 
GTACATTTCC AGCTGCACTT TCTGCTGCGA CCCCTCCAGA CGCTGAGCCT GGGCCTGGAG 
GAGGAGCTAT TGCAGCGAGG GATCCGGGCA AGGCTGCGGG AGCACGGCAT CTCCCTGGCT 
GCCTATGGCA CAATTGTGTC GGCTGAGCTC ACAGGGAGAC ATAAGGGACC CTTGGCAGAA 
AGAGACTTCA AATCAGGCCG CTGTCCAGGG AACTCCTTTT CCTGCGGGAA CAGCCAGTGT 
GTGACCAAGG TGAACCCGGA GTGTGACGAC CAGGAGGACT GCTCCGATGG GTCCGACGAG 
GCGCACTGCG AGTGTGGCTT GCAGCCTGCC TGGAGGATGG CCGGCAGGAT CGTGGGCGGC 
ATGGAAGCAT CCCCGGGGGA GTTTCCGTGG CAAGCCAGCC TTCGAGAGAA CAAGGAGCAC 
TTCTGTGGGG CCGCCATCAT CAACGCCAGG TGGCTGGTGT CTGCTGCTCA CTGCTTCAAT 
GAGTTCCAAG ACCCGACGAA GTGGGTGGCC TACGTGGGTG CGACCTACCT CAGCGGCTCG 
GAGGCCAGCA CCGTGCGGGC CCAGGTGGTC CAGATCGTCA AGCACCCCCT GTACAACGCG 
GACACGGCCG ACTTTGACGT GGCTGTGCTG GAGCTGACCA GCCCTCTGCC TTTCGGCCGG 
CACATCCAGC CCGTGTGCCT CCCGGCTGCC ACACACATCT TCCCACCCAG CAAGAAGTGC 
CTGATCTCAG GCTGGGGCTA CCTCAAGGAG GACTTCCTGG TCAAGCCAGA GGTGCTGCAG 
AAAGCCACTG TGGAGCTGCT GGACCAGGCA CTGTGTGCCA GCTTGTACGG CCATTCACTC 
ACTGACAGGA TGGTGTGCGC TGGCTACCTG GACGGGAAGG TGGACTCCTG CCAGGGTGAC 
TCAGGAGGAC CCCTGGTCTG CGAGGAGCCC TCTGGCCGGT TCTTTCTGGC TGGCATCGTG 
AGCTGGGGAA TCGGGTGTGC GGAAGCCCGG CGTCCAGGGG TCTATGCCCG AGTCACCAGG 
CTACGTGACT GGATCCTGGA GGCCACCACC AAAGCCAGCA TGCCTCTGGC CCCCACCATG 
GCTCCTGCCC CTGCCGCCCC CAGCACAGCC TGGCCCACCA GTCCTGAGAG CCCTGTGGTC 
AGCACCCCCA CCAAATCGAT GCAGGCCCTC AGTACCGTGC CTCTTGACTG GGTCACCGTT 
CCTAAGCTAC AAGAATGTGG GGCCAGGCCT GCAATGGAGA AGCCCACCCG GGTCGTGGGC 
GGGTTCGGAG CTGCCTCCGG GGAGGTGCCC TGGCAGGTCA GCCTGAAGGA AGGGTCCCGG 
CACTTCTGCG GAGCAACTGT GGTGGGGGAC CGCTGGCTGC TGTCTGCCGC CCACTGCTTC 
AACCACACGA AGGTGGAGCA GGTTCGGGCC CACCTGGGCA CTGCGTCCCT CCTGGGCCTG 
GGCGGGAGCC CGGTGAAGAT CGGGCTGCGG CGGGTAGTGC TGCACCCCCT CTACAACCCT 
GGCATCCTGG ACTTCGACCT GGCTGTCCTG GAGCTGGCCA GCCCCCTGGC CTTCAACAAA 
TACATCCAGC CTGTCTGCCT GCCCCTGGCC ATCCAGAAGT TCCCTGTGGG CCGGAAGTGC 
ATGATCTCCG GATGGGGAAA TACGCAGGAA GGAAATGCCA CCAAGCCCGA GCTCCTGCAG 
AAGGCGTCCG TGGGCATCAT AGACCAGAAA ACCTGTAGTG TGCTCTACAA CTTCTCCCTC 
ACAGACCGCA TGATCTGCGC AGGCTTCCTG GAAGGCAAAG TCGACTCCTG CCAGGGTGAC 
TCTGGGGGCC CCCTGGCCTG CGAGGAGGCC CCTGGCGTGT TTTATCTGGC AGGGATCGTG 
AGCTGGGGTA TTGGCTGCGC TCAGGTTAAG AAGCCGGGCG TGTACACGCG CATCACCAGG 
CTAAAGGGCT GGATCCTGGA GATCATGTCC TCCCAGCCCC TTCCCATGTC TCCCCCCTCG 
ACCACAAGGA TGCTGGCCAC CACCAGCCCC AGGACGACAG CTGGCCTCAC AGTCCCGGGG 
GCCACACCCA GCAGACCCAC CCCTGGGGCT GCCAGCAGGG TGACGGGCCA ACCTGCCAAC 
TCAACCTTAT CTGCCGTGAG CACCACTGCT AGGGGACAGA CGCCATTTCC AGACGCCCCG 
GAGGCCACCA CACACACCCA GCTACCAGAC TGTGGCCTGG CGCCGGCCGC GCTCACCAGG 
ATTGTGGGCG GCAGCGCAGC GGGCCGTGGG GAGTGGCCGT GGCAGGTGAG CCTGTGGCTG 
CGGCGCCGGG AACACCGTTG CGGGGCCGTG CTGGTGGCAG AGAGGTGGCT GCTGTCGGCG 
GCGCACTGCT TCGACGTCTA CGGGGACCCC AAGCAGTGGG CGGCCTTCCT AGGCACGCCG 
TTCCTGAGCG GCGCGGAGGG GCAGCTGGAG CGCGTGGCGC GCATCTACAA GCACCCGTTC 
TACAATCTCT ACACGCTCGA CTACGACGTG GCGCTGCTGG AGCTGGCGGG GCCGGTGCGT 
CGCAGCCGCC TGGTGCGTCC CATCTGCCTG CCCGAGCCCG CGCCGCGACC CCCGGACGGC 
ACGCGCTGCG TCATCACCGG CTGGGGCTCG GTGCGCGAAG GAGGCTCCAT GGCGCGGCAG 
CTGCAGAAGG CGGCCGTGCG CCTCCTCAGC GAGCAGACCT GCCGCCGCTT CTACCCAGTG 
CAGATCAGCA GCCGCATGCT GTGTGCCGGC TTCCCGCAGG GTGGCGTGGA CAGCTGCTCG 
GGTGACGCTG GGGGACCCCT GGCCTGCAGG GAGCCCTCTG GACGGTGGGT GCTAACTGGG 
GTCACTAGCT GGGGCTATGG CTGTGGCCGG CCCCACTTCC CAGGTGTCTA TACCCGGGTG 
GCAGCTGTGA GAGGCTGGAT AGGACAGCAC ATCCAGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA.
Oncology reports31(6)2792-6(2014 Jun)
Fontanil T,Mohamedi Y,Esteban MM,Obaya AJ,Cal S

TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.
Journal of molecular neuroscience : MN50(2)250-6(2013 Jun)
Aragam N,Wang KS,Anderson JL,Liu X

Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycans.
The Biochemical journal400(3)551-61(2006 Dec)
Okumura Y,Hayama M,Takahashi E,Fujiuchi M,Shimabukuro A,Yano M,Kido H

Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product.
Proceedings of the National Academy of Sciences of the United States of America100(16)9185-90(2003 Aug)
Cal S,Quesada V,Garabaya C,Lopez-Otin C

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TMPRSS9 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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