Gene Symbol | IL7R |
Entrez Gene ID | 3575 |
Full Name | interleukin 7 receptor |
Synonyms | CD127,CDW127,IL-7R-alpha,IL7RA,ILRA |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]. |
Disorder MIM: | |
Disorder Html: | Severe combined immunodeficiency, T-cell negative, B-cell/natural killer cell-positive type, 608971 (3) |