TAS2R42 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAS2R42
Entrez Gene ID	353164
Full Name	taste 2 receptor member 42
Synonyms	T2R24,T2R42,T2R55,TAS2R55
General protein information	Preferred Names taste 2 receptor member 42 Names taste receptor type 2 member 42 candidate taste receptor hT2R55 taste receptor type 2 member 55 taste receptor, type 2, member 42
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.2
Disorder MIM:	613966

mRNA and Protein(s)

mRNA	Protein	Name
NM_181429.2	NP_852094.2	taste receptor type 2 member 42

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TAS2R42	NP_001138968.1
Rattus norvegicus (Norway rat)	Tas2r145	XP_002729459.1
Mus musculus (house mouse)	Tas2r131	NP_996913.1
Homo sapiens (human)	TAS2R42	NP_852094.1
Pan troglodytes (chimpanzee)	TAS2R42	XP_001137707.2
	TAS2R42	XP_001083226.1

Gene Ontology
Bibliography

Related articles in PubMed

Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.
Thalmann S, Behrens M, Meyerhof W
Biochemical and biophysical research communications435(2)267-73(2013 May)

Patients with phantogeusia show increased expression of T2R taste receptor genes in their tongues.
Hirai R, Takao K, Onoda K, Kokubun S, Ikeda M
The Annals of otology, rhinology, and laryngology121(2)113-8(2012 Feb)

The molecular receptive ranges of human TAS2R bitter taste receptors.
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M
Chemical senses35(2)157-70(2010 Feb)

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Go Y, Satta Y, Takenaka O, Takahata N
Genetics170(1)313-26(2005 May)

Evolution of bitter taste receptors in humans and apes.
Fischer A, Gilad Y, Man O, P??bo S
Molecular biology and evolution22(3)432-6(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Further studies revealed that TAS2R41 is a 'specialist' receptor highly selective for this antibiotic.
Title: Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.

Our results show that the expression rate of some of the T2R taste receptor genes was increased significantly in patients with phantogeusia.
Title: Patients with phantogeusia show increased expression of T2R taste receptor genes in their tongues.

The following TAS2R42 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAS2R42 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu23625	NM_181429.2 Latest version!	Homo sapiens taste 2 receptor member 42 (TAS2R42), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAS2R42 ( NM_181429.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_852094.2 Homo sapiens taste 2 receptor member 42 (TAS2R42), mRNA.

Price & Availability↑

CloneID	OHu23625
Clone ID Related Accession (Same CDS sequence)	NM_181429.2
Accession Version	NM_181429.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	taste receptor type 2 member 42
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC244131.2. On Apr 15, 2014 this sequence version replaced NM_181429.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript is intronless :: BC131742.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000334266.1/ ENSP00000334050.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCCACCG AATTGGACAA AATCTTTCTG ATTCTGGCAA TAGCAGAATT CATCATCAGC 
ATGCTGGGGA ATGTGTTCAT TGGACTGGTA AACTGCTCTG AAGGGATCAA GAACCAAAAG 
GTCTTCTCAG CTGACTTCAT CCTCACCTGC TTGGCTATCT CCACAATTGG ACAACTGTTG 
GTGATACTGT TTGATTCATT TCTAGTGGGA CTTGCTTCAC ATTTATATAC CACATATAGA 
CTAGGAAAAA CTGTTATTAT GCTTTGGCAC ATGACTAATC ACTTGACAAC CTGGCTTGCC 
ACCTGCCTAA GCATTTTCTA TTTCTTTAAG ATAGCCCACT TCCCCCACTC CCTTTTCCTC 
TGGCTGAGGT GGAGGATGAA CGGAATGATT GTTATGCTTC TTATATTGTC TTTGTTCTTA 
CTGATTTTTG ACAGTTTAGT GCTAGAAATA TTTATTGATA TCTCACTCAA TATAATAGAT 
AAAAGTAATC TGACTTTATA TTTAGATGAA AGTAAAACTC TCTATGATAA ACTCTCTATT 
TTAAAAACTC TTCTCAGCTT GACCAGTTTT ATCCCCTTTT CTCTGTTCCT GACCTCCTTG 
CTTTTTTTAT TTCTGTCCTT GGTGAGACAT ACTAGAAATT TGAAGCTCAG TTCCTTGGGC 
TCTAGAGACT CCAGCACAGA GGCCCATAGG AGGGCCATGA AAATGGTGAT GTCTTTCCTT 
TTCCTCTTCA TAGTTCATTT TTTTTCCTTA CAAGTGGCCA ATTGGATATT TTTTATGTTG 
TGGAACAACA AGTGCATAAA GTTTGTCATG TTAGCCTTAA ATGCCTTTCC CTCGTGCCAC 
TCATTTATTC TCATTCTGGG AAACAGCAAG CTGCAACAGA CAGCTGTGAG GCTACTGTGG 
CATCTTAGGA ACTATACAAA AACACCAAAC CCTTTACCTT TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_852094.2
CDS	1..945
Translation	MATELDKIFLILAIAEFIISMLGNVFIGLVNCSEGIKNQKVFSADFILTCLAISTIGQLLVILFDSFLVGLASHLYTTYRLGKTVIMLWHMTNHLTTWLATCLSIFYFFKIAHFPHSLFLWLRWRMNGMIVMLLILSLFLLIFDSLVLEIFIDISLNIIDKSNLTLYLDESKTLYDKLSILKTLLSLTSFIPFSLFLTSLLFLFLSLVRHTRNLKLSSLGSRDSSTEAHRRAMKMVMSFLFLFIVHFFSLQVANWIFFMLWNNKCIKFVMLALNAFPSCHSFILILGNSKLQQTAVRLLWHLRNYTKTPNPLPL

Target ORF information:

RefSeq Version	NM_181429.2
Organism	Homo sapiens(human)
Definition	Homo sapiens taste 2 receptor member 42 (TAS2R42), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181429.2

ORF Insert Sequence:

ATGGCCACCG AATTGGACAA AATCTTTCTG ATTCTGGCAA TAGCAGAATT CATCATCAGC 
ATGCTGGGGA ATGTGTTCAT TGGACTGGTA AACTGCTCTG AAGGGATCAA GAACCAAAAG 
GTCTTCTCAG CTGACTTCAT CCTCACCTGC TTGGCTATCT CCACAATTGG ACAACTGTTG 
GTGATACTGT TTGATTCATT TCTAGTGGGA CTTGCTTCAC ATTTATATAC CACATATAGA 
CTAGGAAAAA CTGTTATTAT GCTTTGGCAC ATGACTAATC ACTTGACAAC CTGGCTTGCC 
ACCTGCCTAA GCATTTTCTA TTTCTTTAAG ATAGCCCACT TCCCCCACTC CCTTTTCCTC 
TGGCTGAGGT GGAGGATGAA CGGAATGATT GTTATGCTTC TTATATTGTC TTTGTTCTTA 
CTGATTTTTG ACAGTTTAGT GCTAGAAATA TTTATTGATA TCTCACTCAA TATAATAGAT 
AAAAGTAATC TGACTTTATA TTTAGATGAA AGTAAAACTC TCTATGATAA ACTCTCTATT 
TTAAAAACTC TTCTCAGCTT GACCAGTTTT ATCCCCTTTT CTCTGTTCCT GACCTCCTTG 
CTTTTTTTAT TTCTGTCCTT GGTGAGACAT ACTAGAAATT TGAAGCTCAG TTCCTTGGGC 
TCTAGAGACT CCAGCACAGA GGCCCATAGG AGGGCCATGA AAATGGTGAT GTCTTTCCTT 
TTCCTCTTCA TAGTTCATTT TTTTTCCTTA CAAGTGGCCA ATTGGATATT TTTTATGTTG 
TGGAACAACA AGTGCATAAA GTTTGTCATG TTAGCCTTAA ATGCCTTTCC CTCGTGCCAC 
TCATTTATTC TCATTCTGGG AAACAGCAAG CTGCAACAGA CAGCTGTGAG GCTACTGTGG 
CATCTTAGGA ACTATACAAA AACACCAAAC CCTTTACCTT TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.
Biochemical and biophysical research communications435(2)267-73(2013 May)
Thalmann S,Behrens M,Meyerhof W

Patients with phantogeusia show increased expression of T2R taste receptor genes in their tongues.
The Annals of otology, rhinology, and laryngology121(2)113-8(2012 Feb)
Hirai R,Takao K,Onoda K,Kokubun S,Ikeda M

The molecular receptive ranges of human TAS2R bitter taste receptors.
Chemical senses35(2)157-70(2010 Feb)
Meyerhof W,Batram C,Kuhn C,Brockhoff A,Chudoba E,Bufe B,Appendino G,Behrens M

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Genetics170(1)313-26(2005 May)
Go Y,Satta Y,Takenaka O,Takahata N

Evolution of bitter taste receptors in humans and apes.
Molecular biology and evolution22(3)432-6(2005 Mar)
Fischer A,Gilad Y,Man O,P??bo S