IGF2R cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IGF2R
Entrez Gene ID	3482
Full Name	insulin like growth factor 2 receptor
Synonyms	CD222,CI-M6PR,CIMPR,M6P-R,M6P/IGF2R,MPR 300,MPR1,MPR300,MPRI
General protein information	Preferred Names insulin like growth factor 2 receptor Names cation-independent mannose-6-phosphate receptor 300 kDa mannose 6-phosphate receptor CI Man-6-P receptor IGF-II receptor M6P/IGF2 receptor insulin-like growth factor II receptor
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 6 Map Location: 6q25.3
Summary	This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015].
Disorder MIM:	147280
Disorder Html:	Hepatocellular carcinoma, somatic, 114550 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000876.3	NP_000867.2	cation-independent mannose-6-phosphate receptor precursor
NM_000876.2	NP_000867.2	cation-independent mannose-6-phosphate receptor precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	IGF2R	NP_776777.1
Xenopus tropicalis (tropical clawed frog)	igf2r	XP_002933917.2
Mus musculus (house mouse)	Igf2r	NP_034645.2
Danio rerio (zebrafish)	igf2r	NP_001034716.1
	IGF2R	XP_002804004.1
Canis lupus familiaris (dog)	IGF2R	NP_001116074.1
Pan troglodytes (chimpanzee)	IGF2R	XP_003311618.2
Homo sapiens (human)	IGF2R	NP_000867.2
Rattus norvegicus (Norway rat)	Igf2r	NP_036888.1
Gallus gallus (chicken)	IGF2R	NP_990301.1

Gene Ontology
Bibliography

Related articles in PubMed

Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse.
Vu TH, Li T, Hoffman AR
Human molecular genetics13(19)2233-45(2004 Oct)

Functional polymorphism in the parental imprinting of the human IGF2R gene.
Xu Y, Goodyer CG, Deal C, Polychronakos C
Biochemical and biophysical research communications197(2)747-54(1993 Dec)

The insulin-like growth factor type-2 receptor gene is imprinted in the mouse but not in humans.
Kalscheuer VM, Mariman EC, Schepens MT, Rehder H, Ropers HH
Nature genetics5(1)74-8(1993 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.
Title: Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.

Heterodimers of the SNX-BAR proteins, SNX1, SNX2, SNX5, and SNX6, are the cargo-selective elements that mediate the retrograde transport of CI-MPR from endosomes to the trans-Golgi networ independently of the core retromer trimer.
Title: Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport.

Findings indicate that IGF2R expression is controlled posttranscriptionally by two factors that associate with Igf2r mRNA and suggest that miR-195 and CUGBP1 dampen IGF signaling by inhibiting IGF2R translation.
Title: Cooperative Repression of Insulin-Like Growth Factor Type 2 Receptor Translation by MicroRNA 195 and RNA-Binding Protein CUGBP1.

Previously characterized disease-causing mutations in IGF2, IGF1R, IGF2R, or IGFALS all were found in the general population but with allele frequencies of <1:30,000.
Title: Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms.

These data suggest the involvement of IGF-2, IGF-1R, IGF-2R and PTEN in temporo-spatial patterning of basic cellular processes (proliferation, differentiation) during normal tooth development.
Title: Involvement of IGF-2, IGF-1R, IGF-2R and PTEN in development of human tooth germ - an immunohistochemical study.

The following IGF2R gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IGF2R cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23427	NM_000876.3 Latest version!	Homo sapiens insulin like growth factor 2 receptor (IGF2R), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$923.30 $1319.00
View Old Accession Versions >>
OHu23427	NM_000876.2	Homo sapiens insulin-like growth factor 2 receptor (IGF2R), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$923.30 $1319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IGF2R ( NM_000876.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_000867.2 Homo sapiens insulin like growth factor 2 receptor (IGF2R), mRNA.

Price & Availability↑

CloneID	OHu23427
Clone ID Related Accession (Same CDS sequence)	NM_000876.3 , NM_000876.2
Accession Version	NM_000876.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Homo sapiens(human)
Product	cation-independent mannose-6-phosphate receptor precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Y00285.1, J03528.1, AL353625.5 and BC010121.2. This sequence is a reference standard in the RefSeqGene project. On Nov 20, 2015 this sequence version replaced NM_000876.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y00285.1, J03528.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## imprinted gene :: PMID: 8267611 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGGCCG CCGCCGGCCG GAGCCCCCAC CTGGGGCCCG CGCCCGCCCG CCGCCCGCAG 
CGCTCTCTGC TCCTGCTGCA GCTGCTGCTG CTCGTCGCTG CCCCGGGGTC CACGCAGGCC 
CAGGCCGCCC CGTTCCCCGA GCTGTGCAGT TATACATGGG AAGCTGTTGA TACCAAAAAT 
AATGTACTTT ATAAAATCAA CATCTGTGGA AGTGTGGATA TTGTCCAGTG CGGGCCATCA 
AGTGCTGTTT GTATGCACGA CTTGAAGACA CGCACTTATC ATTCAGTGGG TGACTCTGTT 
TTGAGAAGTG CAACCAGATC TCTCCTGGAA TTCAACACAA CAGTGAGCTG TGACCAGCAA 
GGCACAAATC ACAGAGTCCA GAGCAGCATT GCCTTCCTGT GTGGGAAAAC CCTGGGAACT 
CCTGAATTTG TAACTGCAAC AGAATGTGTG CACTACTTTG AGTGGAGGAC CACTGCAGCC 
TGCAAGAAAG ACATATTTAA AGCAAATAAG GAGGTGCCAT GCTATGTGTT TGATGAAGAG 
TTGAGGAAGC ATGATCTCAA TCCTCTGATC AAGCTTAGTG GTGCCTACTT GGTGGATGAC 
TCCGATCCGG ACACTTCTCT ATTCATCAAT GTTTGTAGAG ACATAGACAC ACTACGAGAC 
CCAGGTTCAC AGCTGCGGGC CTGTCCCCCC GGCACTGCCG CCTGCCTGGT AAGAGGACAC 
CAGGCGTTTG ATGTTGGCCA GCCCCGGGAC GGACTGAAGC TGGTGCGCAA GGACAGGCTT 
GTCCTGAGTT ACGTGAGGGA AGAGGCAGGA AAGCTAGACT TTTGTGATGG TCACAGCCCT 
GCGGTGACTA TTACATTTGT TTGCCCGTCG GAGCGGAGAG AGGGCACCAT TCCCAAACTC 
ACAGCTAAAT CCAACTGCCG CTATGAAATT GAGTGGATTA CTGAGTATGC CTGCCACAGA 
GATTACCTGG AAAGTAAAAC TTGTTCTCTG AGCGGCGAGC AGCAGGATGT CTCCATAGAC 
CTCACACCAC TTGCCCAGAG CGGAGGTTCA TCCTATATTT CAGATGGAAA AGAATATTTG 
TTTTATTTGA ATGTCTGTGG AGAAACTGAA ATACAGTTCT GTAATAAAAA ACAAGCTGCA 
GTTTGCCAAG TGAAAAAGAG CGATACCTCT CAAGTCAAAG CAGCAGGAAG ATACCACAAT 
CAGACCCTCC GATATTCGGA TGGAGACCTC ACCTTGATAT ATTTTGGAGG TGATGAATGC 
AGCTCAGGGT TTCAGCGGAT GAGCGTCATA AACTTTGAGT GCAATAAAAC CGCAGGTAAC 
GATGGGAAAG GAACTCCTGT ATTCACAGGG GAGGTTGACT GCACCTACTT CTTCACATGG 
GACACGGAAT ACGCCTGTGT TAAGGAGAAG GAAGACCTCC TCTGCGGTGC CACCGACGGG 
AAGAAGCGCT ATGACCTGTC CGCGCTGGTC CGCCATGCAG AACCAGAGCA GAATTGGGAA 
GCTGTGGATG GCAGTCAGAC GGAAACAGAG AAGAAGCATT TTTTCATTAA TATTTGTCAC 
AGAGTGCTGC AGGAAGGCAA GGCACGAGGG TGTCCCGAGG ACGCGGCAGT GTGTGCAGTG 
GATAAAAATG GAAGTAAAAA TCTGGGAAAA TTTATTTCCT CTCCCATGAA AGAGAAAGGA 
AACATTCAAC TCTCTTATTC AGATGGTGAT GATTGTGGTC ATGGCAAGAA AATTAAAACT 
AATATCACAC TTGTATGCAA GCCAGGTGAT CTGGAAAGTG CACCAGTGTT GAGAACTTCT 
GGGGAAGGCG GTTGCTTTTA TGAGTTTGAG TGGCACACAG CTGCGGCCTG TGTGCTGTCT 
AAGACAGAAG GGGAGAACTG CACGGTCTTT GACTCCCAGG CAGGGTTTTC TTTTGACTTA 
TCACCTCTCA CAAAGAAAAA TGGTGCCTAT AAAGTTGAGA CAAAGAAGTA TGACTTTTAT 
ATAAATGTGT GTGGCCCGGT GTCTGTGAGC CCCTGTCAGC CAGACTCAGG AGCCTGCCAG 
GTGGCAAAAA GTGATGAGAA GACTTGGAAC TTGGGTCTGA GTAATGCGAA GCTTTCATAT 
TATGATGGGA TGATCCAACT GAACTACAGA GGCGGCACAC CCTATAACAA TGAAAGACAC 
ACACCGAGAG CTACGCTCAT CACCTTTCTC TGTGATCGAG ACGCGGGAGT GGGCTTCCCT 
GAATATCAGG AAGAGGATAA CTCCACCTAC AACTTCCGGT GGTACACCAG CTATGCCTGC 
CCGGAGGAGC CCCTGGAATG CGTAGTGACC GACCCCTCCA CGCTGGAGCA GTACGACCTC 
TCCAGTCTGG CAAAATCTGA AGGTGGCCTT GGAGGAAACT GGTATGCCAT GGACAACTCA 
GGGGAACATG TCACGTGGAG GAAATACTAC ATTAACGTGT GTCGGCCTCT GAATCCAGTG 
CCGGGCTGCA ACCGATATGC ATCGGCTTGC CAGATGAAGT ATGAAAAAGA TCAGGGCTCC 
TTCACTGAAG TGGTTTCCAT CAGTAACTTG GGAATGGCAA AGACCGGCCC GGTGGTTGAG 
GACAGCGGCA GCCTCCTTCT GGAATACGTG AATGGGTCGG CCTGCACCAC CAGCGATGGC 
AGACAGACCA CATATACCAC GAGGATCCAT CTCGTCTGCT CCAGGGGCAG GCTGAACAGC 
CACCCCATCT TTTCTCTCAA CTGGGAGTGT GTGGTCAGTT TCCTGTGGAA CACAGAGGCT 
GCCTGTCCCA TTCAGACAAC GACGGATACA GACCAGGCTT GCTCTATAAG GGATCCCAAC 
AGTGGATTTG TGTTTAATCT TAATCCGCTA AACAGTTCGC AAGGATATAA CGTCTCTGGC 
ATTGGGAAGA TTTTTATGTT TAATGTCTGC GGCACAATGC CTGTCTGTGG GACCATCCTG 
GGAAAACCTG CTTCTGGCTG TGAGGCAGAA ACCCAAACTG AAGAGCTCAA GAATTGGAAG 
CCAGCAAGGC CAGTCGGAAT TGAGAAAAGC CTCCAGCTGT CCACAGAGGG CTTCATCACT 
CTGACCTACA AAGGGCCTCT CTCTGCCAAA GGTACCGCTG ATGCTTTTAT CGTCCGCTTT 
GTTTGCAATG ATGATGTTTA CTCAGGGCCC CTCAAATTCC TGCATCAAGA TATCGACTCT 
GGGCAAGGGA TCCGAAACAC TTACTTTGAG TTTGAAACCG CGTTGGCCTG TGTTCCTTCT 
CCAGTGGACT GCCAAGTCAC CGACCTGGCT GGAAATGAGT ACGACCTGAC TGGCCTAAGC 
ACAGTCAGGA AACCTTGGAC GGCTGTTGAC ACCTCTGTCG ATGGGAGAAA GAGGACTTTC 
TATTTGAGCG TTTGCAATCC TCTCCCTTAC ATTCCTGGAT GCCAGGGCAG CGCAGTGGGG 
TCTTGCTTAG TGTCAGAAGG CAATAGCTGG AATCTGGGTG TGGTGCAGAT GAGTCCCCAA 
GCCGCGGCGA ATGGATCTTT GAGCATCATG TATGTCAACG GTGACAAGTG TGGGAACCAG 
CGCTTCTCCA CCAGGATCAC GTTTGAGTGT GCTCAGATAT CGGGCTCACC AGCATTTCAG 
CTTCAGGATG GTTGTGAGTA CGTGTTTATC TGGAGAACTG TGGAAGCCTG TCCCGTTGTC 
AGAGTGGAAG GGGACAACTG TGAGGTGAAA GACCCAAGGC ATGGCAACTT GTATGACCTG 
AAGCCCCTGG GCCTCAACGA CACCATCGTG AGCGCTGGCG AATACACTTA TTACTTCCGG 
GTCTGTGGGA AGCTTTCCTC AGACGTCTGC CCCACAAGTG ACAAGTCCAA GGTGGTCTCC 
TCATGTCAGG AAAAGCGGGA ACCGCAGGGA TTTCACAAAG TGGCAGGTCT CCTGACTCAG 
AAGCTAACTT ATGAAAATGG CTTGTTAAAA ATGAACTTCA CGGGGGGGGA CACTTGCCAT 
AAGGTTTATC AGCGCTCCAC AGCCATCTTC TTCTACTGTG ACCGCGGCAC CCAGCGGCCA 
GTATTTCTAA AGGAGACTTC AGATTGTTCC TACTTGTTTG AGTGGCGAAC GCAGTATGCC 
TGCCCACCTT TCGATCTGAC TGAATGTTCA TTCAAAGATG GGGCTGGCAA CTCCTTCGAC 
CTCTCGTCCC TGTCAAGGTA CAGTGACAAC TGGGAAGCCA TCACTGGGAC GGGGGACCCG 
GAGCACTACC TCATCAATGT CTGCAAGTCT CTGGCCCCGC AGGCTGGCAC TGAGCCGTGC 
CCTCCAGAAG CAGCCGCGTG TCTGCTGGGT GGCTCCAAGC CCGTGAACCT CGGCAGGGTA 
AGGGACGGAC CTCAGTGGAG AGATGGCATA ATTGTCCTGA AATACGTTGA TGGCGACTTA 
TGTCCAGATG GGATTCGGAA AAAGTCAACC ACCATCCGAT TCACCTGCAG CGAGAGCCAA 
GTGAACTCCA GGCCCATGTT CATCAGCGCC GTGGAGGACT GTGAGTACAC CTTTGCCTGG 
CCCACAGCCA CAGCCTGTCC CATGAAGAGC AACGAGCATG ATGACTGCCA GGTCACCAAC 
CCAAGCACAG GACACCTGTT TGATCTGAGC TCCTTAAGTG GCAGGGCGGG ATTCACAGCT 
GCTTACAGCG AGAAGGGGTT GGTTTACATG AGCATCTGTG GGGAGAATGA AAACTGCCCT 
CCTGGCGTGG GGGCCTGCTT TGGACAGACC AGGATTAGCG TGGGCAAGGC CAACAAGAGG 
CTGAGATACG TGGACCAGGT CCTGCAGCTG GTGTACAAGG ATGGGTCCCC TTGTCCCTCC 
AAATCCGGCC TGAGCTATAA GAGTGTGATC AGTTTCGTGT GCAGGCCTGA GGCCGGGCCA 
ACCAATAGGC CCATGCTCAT CTCCCTGGAC AAGCAGACAT GCACTCTCTT CTTCTCCTGG 
CACACGCCGC TGGCCTGCGA GCAAGCGACC GAATGTTCCG TGAGGAATGG AAGCTCTATT 
GTTGACTTGT CTCCCCTTAT TCATCGCACT GGTGGTTATG AGGCTTATGA TGAGAGTGAG 
GATGATGCCT CCGATACCAA CCCTGATTTC TACATCAATA TTTGTCAGCC ACTAAATCCC 
ATGCACGGAG TGCCCTGTCC TGCCGGAGCC GCTGTGTGCA AAGTTCCTAT TGATGGTCCC 
CCCATAGATA TCGGCCGGGT AGCAGGACCA CCAATACTCA ATCCAATAGC AAATGAGATT 
TACTTGAATT TTGAAAGCAG TACTCCTTGC TTAGCGGACA AGCATTTCAA CTACACCTCG 
CTCATCGCGT TTCACTGTAA GAGAGGTGTG AGCATGGGAA CGCCTAAGCT GTTAAGGACC 
AGCGAGTGCG ACTTTGTGTT CGAATGGGAG ACTCCTGTCG TCTGTCCTGA TGAAGTGAGG 
ATGGATGGCT GTACCCTGAC AGATGAGCAG CTCCTCTACA GCTTCAACTT GTCCAGCCTT 
TCCACGAGCA CCTTTAAGGT GACTCGCGAC TCGCGCACCT ACAGCGTTGG GGTGTGCACC 
TTTGCAGTCG GGCCAGAACA AGGAGGCTGT AAGGACGGAG GAGTCTGTCT GCTCTCAGGC 
ACCAAGGGGG CATCCTTTGG ACGGCTGCAA TCAATGAAAC TGGATTACAG GCACCAGGAT 
GAAGCGGTCG TTTTAAGTTA CGTGAATGGT GATCGTTGCC CTCCAGAAAC CGATGACGGC 
GTCCCCTGTG TCTTCCCCTT CATATTCAAT GGGAAGAGCT ACGAGGAGTG CATCATAGAG 
AGCAGGGCGA AGCTGTGGTG TAGCACAACT GCGGACTACG ACAGAGACCA CGAGTGGGGC 
TTCTGCAGAC ACTCAAACAG CTACCGGACA TCCAGCATCA TATTTAAGTG TGATGAAGAT 
GAGGACATTG GGAGGCCACA AGTCTTCAGT GAAGTGCGTG GGTGTGATGT GACATTTGAG 
TGGAAAACAA AAGTTGTCTG CCCTCCAAAG AAGTTGGAGT GCAAATTCGT CCAGAAACAC 
AAAACCTACG ACCTGCGGCT GCTCTCCTCT CTCACCGGGT CCTGGTCCCT GGTCCACAAC 
GGAGTCTCGT ACTATATAAA TCTGTGCCAG AAAATATATA AAGGGCCCCT GGGCTGCTCT 
GAAAGGGCCA GCATTTGCAG AAGGACCACA ACTGGTGACG TCCAGGTCCT GGGACTCGTT 
CACACGCAGA AGCTGGGTGT CATAGGTGAC AAAGTTGTTG TCACGTACTC CAAAGGTTAT 
CCGTGTGGTG GAAATAAGAC CGCATCCTCC GTGATAGAAT TGACCTGTAC AAAGACGGTG 
GGCAGACCTG CATTCAAGAG GTTTGATATC GACAGCTGCA CTTACTACTT CAGCTGGGAC 
TCCCGGGCTG CCTGCGCCGT GAAGCCTCAG GAGGTGCAGA TGGTGAATGG GACCATCACC 
AACCCTATAA ATGGCAAGAG CTTCAGCCTC GGAGATATTT ATTTTAAGCT GTTCAGAGCC 
TCTGGGGACA TGAGGACCAA TGGGGACAAC TACCTGTATG AGATCCAACT TTCCTCCATC 
ACAAGCTCCA GAAACCCGGC GTGCTCTGGA GCCAACATAT GCCAGGTGAA GCCCAACGAT 
CAGCACTTCA GTCGGAAAGT TGGAACCTCT GACAAGACCA AGTACTACCT TCAAGACGGC 
GATCTCGATG TCGTGTTTGC CTCTTCCTCT AAGTGCGGAA AGGATAAGAC CAAGTCTGTT 
TCTTCCACCA TCTTCTTCCA CTGTGACCCT CTGGTGGAGG ACGGGATCCC CGAGTTCAGT 
CACGAGACTG CCGACTGCCA GTACCTCTTC TCTTGGTACA CCTCAGCCGT GTGTCCTCTG 
GGGGTGGGCT TTGACAGCGA GAATCCCGGG GACGACGGGC AGATGCACAA GGGGCTGTCA 
GAACGGAGCC AGGCAGTCGG CGCGGTGCTC AGCCTGCTGC TGGTGGCGCT CACCTGCTGC 
CTGCTGGCCC TGTTGCTCTA CAAGAAGGAG AGGAGGGAAA CAGTGATAAG TAAGCTGACC 
ACTTGCTGTA GGAGAAGTTC CAACGTGTCC TACAAATACT CAAAGGTGAA TAAGGAAGAA 
GAGACAGATG AGAATGAAAC AGAGTGGCTG ATGGAAGAGA TCCAGCTGCC TCCTCCACGG 
CAGGGAAAGG AAGGGCAGGA GAACGGCCAT ATTACCACCA AGTCAGTGAA AGCCCTCAGC 
TCCCTGCATG GGGATGACCA GGACAGTGAG GATGAGGTTC TGACCATCCC AGAGGTGAAA 
GTTCACTCGG GCAGGGGAGC TGGGGCAGAG AGCTCCCACC CAGTGAGAAA CGCACAGAGC 
AATGCCCTTC AGGAGCGTGA GGACGATAGG GTGGGGCTGG TCAGGGGTGA GAAGGCGAGG 
AAAGGGAAGT CCAGCTCTGC ACAGCAGAAG ACAGTGAGCT CCACCAAGCT GGTGTCCTTC 
CATGACGACA GCGACGAGGA CCTCTTACAC ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000867.2
CDS	149..7624
Translation	MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAPFPELCSYTWEAVDTKNNVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQGTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTLRDPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYLFYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDECSSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDGKKRYDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVLSKTEGENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFYINVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERHTPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDLSSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGSFTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNSHPIFSLNWECVVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSGIGKIFMFNVCGTMPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFITLTYKGPLSAKGTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPSPVDCQVTDLAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVGSCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQLQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFRVCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCHKVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNSFDLSSLSRYSDNWEAITGTGDPEHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVNLGRVRDGPQWRDGIIVLKYVDGDLCPDGIRKKSTTIRFTCSESQVNSRPMFISAVEDCEYTFAWPTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYDESEDDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEIYLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVRMDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSGTKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDGVPCVFPFIFNGKSYEECIIESRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDEDEDIGRPQVFSEVRGCDVTFEWKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQKIYKGPLGCSERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTVGRPAFKRFDIDSCTYYFSWDSRAACAVKPQEVQMVNGTITNPINGKSFSLGDIYFKLFRASGDMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDQHFSRKVGTSDKTKYYLQDGDLDVVFASSSKCGKDKTKSVSSTIFFHCDPLVEDGIPEFSHETADCQYLFSWYTSAVCPLGVGFDSENPGDDGQMHKGLSERSQAVGAVLSLLLVALTCCLLALLLYKKERRETVISKLTTCCRRSSNVSYKYSKVNKEEETDENETEWLMEEIQLPPPRQGKEGQENGHITTKSVKALSSLHGDDQDSEDEVLTIPEVKVHSGRGAGAESSHPVRNAQSNALQEREDDRVGLVRGEKARKGKSSSAQQKTVSSTKLVSFHDDSDEDLLHI

Target ORF information:

RefSeq Version	NM_000876.3
Organism	Homo sapiens(human)
Definition	Homo sapiens insulin like growth factor 2 receptor (IGF2R), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000876.3

ORF Insert Sequence:

ATGGGGGCCG CCGCCGGCCG GAGCCCCCAC CTGGGGCCCG CGCCCGCCCG CCGCCCGCAG 
CGCTCTCTGC TCCTGCTGCA GCTGCTGCTG CTCGTCGCTG CCCCGGGGTC CACGCAGGCC 
CAGGCCGCCC CGTTCCCCGA GCTGTGCAGT TATACATGGG AAGCTGTTGA TACCAAAAAT 
AATGTACTTT ATAAAATCAA CATCTGTGGA AGTGTGGATA TTGTCCAGTG CGGGCCATCA 
AGTGCTGTTT GTATGCACGA CTTGAAGACA CGCACTTATC ATTCAGTGGG TGACTCTGTT 
TTGAGAAGTG CAACCAGATC TCTCCTGGAA TTCAACACAA CAGTGAGCTG TGACCAGCAA 
GGCACAAATC ACAGAGTCCA GAGCAGCATT GCCTTCCTGT GTGGGAAAAC CCTGGGAACT 
CCTGAATTTG TAACTGCAAC AGAATGTGTG CACTACTTTG AGTGGAGGAC CACTGCAGCC 
TGCAAGAAAG ACATATTTAA AGCAAATAAG GAGGTGCCAT GCTATGTGTT TGATGAAGAG 
TTGAGGAAGC ATGATCTCAA TCCTCTGATC AAGCTTAGTG GTGCCTACTT GGTGGATGAC 
TCCGATCCGG ACACTTCTCT ATTCATCAAT GTTTGTAGAG ACATAGACAC ACTACGAGAC 
CCAGGTTCAC AGCTGCGGGC CTGTCCCCCC GGCACTGCCG CCTGCCTGGT AAGAGGACAC 
CAGGCGTTTG ATGTTGGCCA GCCCCGGGAC GGACTGAAGC TGGTGCGCAA GGACAGGCTT 
GTCCTGAGTT ACGTGAGGGA AGAGGCAGGA AAGCTAGACT TTTGTGATGG TCACAGCCCT 
GCGGTGACTA TTACATTTGT TTGCCCGTCG GAGCGGAGAG AGGGCACCAT TCCCAAACTC 
ACAGCTAAAT CCAACTGCCG CTATGAAATT GAGTGGATTA CTGAGTATGC CTGCCACAGA 
GATTACCTGG AAAGTAAAAC TTGTTCTCTG AGCGGCGAGC AGCAGGATGT CTCCATAGAC 
CTCACACCAC TTGCCCAGAG CGGAGGTTCA TCCTATATTT CAGATGGAAA AGAATATTTG 
TTTTATTTGA ATGTCTGTGG AGAAACTGAA ATACAGTTCT GTAATAAAAA ACAAGCTGCA 
GTTTGCCAAG TGAAAAAGAG CGATACCTCT CAAGTCAAAG CAGCAGGAAG ATACCACAAT 
CAGACCCTCC GATATTCGGA TGGAGACCTC ACCTTGATAT ATTTTGGAGG TGATGAATGC 
AGCTCAGGGT TTCAGCGGAT GAGCGTCATA AACTTTGAGT GCAATAAAAC CGCAGGTAAC 
GATGGGAAAG GAACTCCTGT ATTCACAGGG GAGGTTGACT GCACCTACTT CTTCACATGG 
GACACGGAAT ACGCCTGTGT TAAGGAGAAG GAAGACCTCC TCTGCGGTGC CACCGACGGG 
AAGAAGCGCT ATGACCTGTC CGCGCTGGTC CGCCATGCAG AACCAGAGCA GAATTGGGAA 
GCTGTGGATG GCAGTCAGAC GGAAACAGAG AAGAAGCATT TTTTCATTAA TATTTGTCAC 
AGAGTGCTGC AGGAAGGCAA GGCACGAGGG TGTCCCGAGG ACGCGGCAGT GTGTGCAGTG 
GATAAAAATG GAAGTAAAAA TCTGGGAAAA TTTATTTCCT CTCCCATGAA AGAGAAAGGA 
AACATTCAAC TCTCTTATTC AGATGGTGAT GATTGTGGTC ATGGCAAGAA AATTAAAACT 
AATATCACAC TTGTATGCAA GCCAGGTGAT CTGGAAAGTG CACCAGTGTT GAGAACTTCT 
GGGGAAGGCG GTTGCTTTTA TGAGTTTGAG TGGCACACAG CTGCGGCCTG TGTGCTGTCT 
AAGACAGAAG GGGAGAACTG CACGGTCTTT GACTCCCAGG CAGGGTTTTC TTTTGACTTA 
TCACCTCTCA CAAAGAAAAA TGGTGCCTAT AAAGTTGAGA CAAAGAAGTA TGACTTTTAT 
ATAAATGTGT GTGGCCCGGT GTCTGTGAGC CCCTGTCAGC CAGACTCAGG AGCCTGCCAG 
GTGGCAAAAA GTGATGAGAA GACTTGGAAC TTGGGTCTGA GTAATGCGAA GCTTTCATAT 
TATGATGGGA TGATCCAACT GAACTACAGA GGCGGCACAC CCTATAACAA TGAAAGACAC 
ACACCGAGAG CTACGCTCAT CACCTTTCTC TGTGATCGAG ACGCGGGAGT GGGCTTCCCT 
GAATATCAGG AAGAGGATAA CTCCACCTAC AACTTCCGGT GGTACACCAG CTATGCCTGC 
CCGGAGGAGC CCCTGGAATG CGTAGTGACC GACCCCTCCA CGCTGGAGCA GTACGACCTC 
TCCAGTCTGG CAAAATCTGA AGGTGGCCTT GGAGGAAACT GGTATGCCAT GGACAACTCA 
GGGGAACATG TCACGTGGAG GAAATACTAC ATTAACGTGT GTCGGCCTCT GAATCCAGTG 
CCGGGCTGCA ACCGATATGC ATCGGCTTGC CAGATGAAGT ATGAAAAAGA TCAGGGCTCC 
TTCACTGAAG TGGTTTCCAT CAGTAACTTG GGAATGGCAA AGACCGGCCC GGTGGTTGAG 
GACAGCGGCA GCCTCCTTCT GGAATACGTG AATGGGTCGG CCTGCACCAC CAGCGATGGC 
AGACAGACCA CATATACCAC GAGGATCCAT CTCGTCTGCT CCAGGGGCAG GCTGAACAGC 
CACCCCATCT TTTCTCTCAA CTGGGAGTGT GTGGTCAGTT TCCTGTGGAA CACAGAGGCT 
GCCTGTCCCA TTCAGACAAC GACGGATACA GACCAGGCTT GCTCTATAAG GGATCCCAAC 
AGTGGATTTG TGTTTAATCT TAATCCGCTA AACAGTTCGC AAGGATATAA CGTCTCTGGC 
ATTGGGAAGA TTTTTATGTT TAATGTCTGC GGCACAATGC CTGTCTGTGG GACCATCCTG 
GGAAAACCTG CTTCTGGCTG TGAGGCAGAA ACCCAAACTG AAGAGCTCAA GAATTGGAAG 
CCAGCAAGGC CAGTCGGAAT TGAGAAAAGC CTCCAGCTGT CCACAGAGGG CTTCATCACT 
CTGACCTACA AAGGGCCTCT CTCTGCCAAA GGTACCGCTG ATGCTTTTAT CGTCCGCTTT 
GTTTGCAATG ATGATGTTTA CTCAGGGCCC CTCAAATTCC TGCATCAAGA TATCGACTCT 
GGGCAAGGGA TCCGAAACAC TTACTTTGAG TTTGAAACCG CGTTGGCCTG TGTTCCTTCT 
CCAGTGGACT GCCAAGTCAC CGACCTGGCT GGAAATGAGT ACGACCTGAC TGGCCTAAGC 
ACAGTCAGGA AACCTTGGAC GGCTGTTGAC ACCTCTGTCG ATGGGAGAAA GAGGACTTTC 
TATTTGAGCG TTTGCAATCC TCTCCCTTAC ATTCCTGGAT GCCAGGGCAG CGCAGTGGGG 
TCTTGCTTAG TGTCAGAAGG CAATAGCTGG AATCTGGGTG TGGTGCAGAT GAGTCCCCAA 
GCCGCGGCGA ATGGATCTTT GAGCATCATG TATGTCAACG GTGACAAGTG TGGGAACCAG 
CGCTTCTCCA CCAGGATCAC GTTTGAGTGT GCTCAGATAT CGGGCTCACC AGCATTTCAG 
CTTCAGGATG GTTGTGAGTA CGTGTTTATC TGGAGAACTG TGGAAGCCTG TCCCGTTGTC 
AGAGTGGAAG GGGACAACTG TGAGGTGAAA GACCCAAGGC ATGGCAACTT GTATGACCTG 
AAGCCCCTGG GCCTCAACGA CACCATCGTG AGCGCTGGCG AATACACTTA TTACTTCCGG 
GTCTGTGGGA AGCTTTCCTC AGACGTCTGC CCCACAAGTG ACAAGTCCAA GGTGGTCTCC 
TCATGTCAGG AAAAGCGGGA ACCGCAGGGA TTTCACAAAG TGGCAGGTCT CCTGACTCAG 
AAGCTAACTT ATGAAAATGG CTTGTTAAAA ATGAACTTCA CGGGGGGGGA CACTTGCCAT 
AAGGTTTATC AGCGCTCCAC AGCCATCTTC TTCTACTGTG ACCGCGGCAC CCAGCGGCCA 
GTATTTCTAA AGGAGACTTC AGATTGTTCC TACTTGTTTG AGTGGCGAAC GCAGTATGCC 
TGCCCACCTT TCGATCTGAC TGAATGTTCA TTCAAAGATG GGGCTGGCAA CTCCTTCGAC 
CTCTCGTCCC TGTCAAGGTA CAGTGACAAC TGGGAAGCCA TCACTGGGAC GGGGGACCCG 
GAGCACTACC TCATCAATGT CTGCAAGTCT CTGGCCCCGC AGGCTGGCAC TGAGCCGTGC 
CCTCCAGAAG CAGCCGCGTG TCTGCTGGGT GGCTCCAAGC CCGTGAACCT CGGCAGGGTA 
AGGGACGGAC CTCAGTGGAG AGATGGCATA ATTGTCCTGA AATACGTTGA TGGCGACTTA 
TGTCCAGATG GGATTCGGAA AAAGTCAACC ACCATCCGAT TCACCTGCAG CGAGAGCCAA 
GTGAACTCCA GGCCCATGTT CATCAGCGCC GTGGAGGACT GTGAGTACAC CTTTGCCTGG 
CCCACAGCCA CAGCCTGTCC CATGAAGAGC AACGAGCATG ATGACTGCCA GGTCACCAAC 
CCAAGCACAG GACACCTGTT TGATCTGAGC TCCTTAAGTG GCAGGGCGGG ATTCACAGCT 
GCTTACAGCG AGAAGGGGTT GGTTTACATG AGCATCTGTG GGGAGAATGA AAACTGCCCT 
CCTGGCGTGG GGGCCTGCTT TGGACAGACC AGGATTAGCG TGGGCAAGGC CAACAAGAGG 
CTGAGATACG TGGACCAGGT CCTGCAGCTG GTGTACAAGG ATGGGTCCCC TTGTCCCTCC 
AAATCCGGCC TGAGCTATAA GAGTGTGATC AGTTTCGTGT GCAGGCCTGA GGCCGGGCCA 
ACCAATAGGC CCATGCTCAT CTCCCTGGAC AAGCAGACAT GCACTCTCTT CTTCTCCTGG 
CACACGCCGC TGGCCTGCGA GCAAGCGACC GAATGTTCCG TGAGGAATGG AAGCTCTATT 
GTTGACTTGT CTCCCCTTAT TCATCGCACT GGTGGTTATG AGGCTTATGA TGAGAGTGAG 
GATGATGCCT CCGATACCAA CCCTGATTTC TACATCAATA TTTGTCAGCC ACTAAATCCC 
ATGCACGGAG TGCCCTGTCC TGCCGGAGCC GCTGTGTGCA AAGTTCCTAT TGATGGTCCC 
CCCATAGATA TCGGCCGGGT AGCAGGACCA CCAATACTCA ATCCAATAGC AAATGAGATT 
TACTTGAATT TTGAAAGCAG TACTCCTTGC TTAGCGGACA AGCATTTCAA CTACACCTCG 
CTCATCGCGT TTCACTGTAA GAGAGGTGTG AGCATGGGAA CGCCTAAGCT GTTAAGGACC 
AGCGAGTGCG ACTTTGTGTT CGAATGGGAG ACTCCTGTCG TCTGTCCTGA TGAAGTGAGG 
ATGGATGGCT GTACCCTGAC AGATGAGCAG CTCCTCTACA GCTTCAACTT GTCCAGCCTT 
TCCACGAGCA CCTTTAAGGT GACTCGCGAC TCGCGCACCT ACAGCGTTGG GGTGTGCACC 
TTTGCAGTCG GGCCAGAACA AGGAGGCTGT AAGGACGGAG GAGTCTGTCT GCTCTCAGGC 
ACCAAGGGGG CATCCTTTGG ACGGCTGCAA TCAATGAAAC TGGATTACAG GCACCAGGAT 
GAAGCGGTCG TTTTAAGTTA CGTGAATGGT GATCGTTGCC CTCCAGAAAC CGATGACGGC 
GTCCCCTGTG TCTTCCCCTT CATATTCAAT GGGAAGAGCT ACGAGGAGTG CATCATAGAG 
AGCAGGGCGA AGCTGTGGTG TAGCACAACT GCGGACTACG ACAGAGACCA CGAGTGGGGC 
TTCTGCAGAC ACTCAAACAG CTACCGGACA TCCAGCATCA TATTTAAGTG TGATGAAGAT 
GAGGACATTG GGAGGCCACA AGTCTTCAGT GAAGTGCGTG GGTGTGATGT GACATTTGAG 
TGGAAAACAA AAGTTGTCTG CCCTCCAAAG AAGTTGGAGT GCAAATTCGT CCAGAAACAC 
AAAACCTACG ACCTGCGGCT GCTCTCCTCT CTCACCGGGT CCTGGTCCCT GGTCCACAAC 
GGAGTCTCGT ACTATATAAA TCTGTGCCAG AAAATATATA AAGGGCCCCT GGGCTGCTCT 
GAAAGGGCCA GCATTTGCAG AAGGACCACA ACTGGTGACG TCCAGGTCCT GGGACTCGTT 
CACACGCAGA AGCTGGGTGT CATAGGTGAC AAAGTTGTTG TCACGTACTC CAAAGGTTAT 
CCGTGTGGTG GAAATAAGAC CGCATCCTCC GTGATAGAAT TGACCTGTAC AAAGACGGTG 
GGCAGACCTG CATTCAAGAG GTTTGATATC GACAGCTGCA CTTACTACTT CAGCTGGGAC 
TCCCGGGCTG CCTGCGCCGT GAAGCCTCAG GAGGTGCAGA TGGTGAATGG GACCATCACC 
AACCCTATAA ATGGCAAGAG CTTCAGCCTC GGAGATATTT ATTTTAAGCT GTTCAGAGCC 
TCTGGGGACA TGAGGACCAA TGGGGACAAC TACCTGTATG AGATCCAACT TTCCTCCATC 
ACAAGCTCCA GAAACCCGGC GTGCTCTGGA GCCAACATAT GCCAGGTGAA GCCCAACGAT 
CAGCACTTCA GTCGGAAAGT TGGAACCTCT GACAAGACCA AGTACTACCT TCAAGACGGC 
GATCTCGATG TCGTGTTTGC CTCTTCCTCT AAGTGCGGAA AGGATAAGAC CAAGTCTGTT 
TCTTCCACCA TCTTCTTCCA CTGTGACCCT CTGGTGGAGG ACGGGATCCC CGAGTTCAGT 
CACGAGACTG CCGACTGCCA GTACCTCTTC TCTTGGTACA CCTCAGCCGT GTGTCCTCTG 
GGGGTGGGCT TTGACAGCGA GAATCCCGGG GACGACGGGC AGATGCACAA GGGGCTGTCA 
GAACGGAGCC AGGCAGTCGG CGCGGTGCTC AGCCTGCTGC TGGTGGCGCT CACCTGCTGC 
CTGCTGGCCC TGTTGCTCTA CAAGAAGGAG AGGAGGGAAA CAGTGATAAG TAAGCTGACC 
ACTTGCTGTA GGAGAAGTTC CAACGTGTCC TACAAATACT CAAAGGTGAA TAAGGAAGAA 
GAGACAGATG AGAATGAAAC AGAGTGGCTG ATGGAAGAGA TCCAGCTGCC TCCTCCACGG 
CAGGGAAAGG AAGGGCAGGA GAACGGCCAT ATTACCACCA AGTCAGTGAA AGCCCTCAGC 
TCCCTGCATG GGGATGACCA GGACAGTGAG GATGAGGTTC TGACCATCCC AGAGGTGAAA 
GTTCACTCGG GCAGGGGAGC TGGGGCAGAG AGCTCCCACC CAGTGAGAAA CGCACAGAGC 
AATGCCCTTC AGGAGCGTGA GGACGATAGG GTGGGGCTGG TCAGGGGTGA GAAGGCGAGG 
AAAGGGAAGT CCAGCTCTGC ACAGCAGAAG ACAGTGAGCT CCACCAAGCT GGTGTCCTTC 
CATGACGACA GCGACGAGGA CCTCTTACAC ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IGF2R ( NM_000876.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_000867.2 Homo sapiens insulin-like growth factor 2 receptor (IGF2R), mRNA.

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CloneID	OHu23427
Clone ID Related Accession (Same CDS sequence)	NM_000876.3 , NM_000876.2
Accession Version	NM_000876.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-05-20
Organism	Homo sapiens(Human)
Product	cation-independent mannose-6-phosphate receptor precursor
Comment

ATGGGGGCCG CCGCCGGCCG GAGCCCCCAC CTGGGGCCCG CGCCCGCCCG CCGCCCGCAG 
CGCTCTCTGC TCCTGCTGCA GCTGCTGCTG CTCGTCGCTG CCCCGGGGTC CACGCAGGCC 
CAGGCCGCCC CGTTCCCCGA GCTGTGCAGT TATACATGGG AAGCTGTTGA TACCAAAAAT 
AATGTACTTT ATAAAATCAA CATCTGTGGA AGTGTGGATA TTGTCCAGTG CGGGCCATCA 
AGTGCTGTTT GTATGCACGA CTTGAAGACA CGCACTTATC ATTCAGTGGG TGACTCTGTT 
TTGAGAAGTG CAACCAGATC TCTCCTGGAA TTCAACACAA CAGTGAGCTG TGACCAGCAA 
GGCACAAATC ACAGAGTCCA GAGCAGCATT GCCTTCCTGT GTGGGAAAAC CCTGGGAACT 
CCTGAATTTG TAACTGCAAC AGAATGTGTG CACTACTTTG AGTGGAGGAC CACTGCAGCC 
TGCAAGAAAG ACATATTTAA AGCAAATAAG GAGGTGCCAT GCTATGTGTT TGATGAAGAG 
TTGAGGAAGC ATGATCTCAA TCCTCTGATC AAGCTTAGTG GTGCCTACTT GGTGGATGAC 
TCCGATCCGG ACACTTCTCT ATTCATCAAT GTTTGTAGAG ACATAGACAC ACTACGAGAC 
CCAGGTTCAC AGCTGCGGGC CTGTCCCCCC GGCACTGCCG CCTGCCTGGT AAGAGGACAC 
CAGGCGTTTG ATGTTGGCCA GCCCCGGGAC GGACTGAAGC TGGTGCGCAA GGACAGGCTT 
GTCCTGAGTT ACGTGAGGGA AGAGGCAGGA AAGCTAGACT TTTGTGATGG TCACAGCCCT 
GCGGTGACTA TTACATTTGT TTGCCCGTCG GAGCGGAGAG AGGGCACCAT TCCCAAACTC 
ACAGCTAAAT CCAACTGCCG CTATGAAATT GAGTGGATTA CTGAGTATGC CTGCCACAGA 
GATTACCTGG AAAGTAAAAC TTGTTCTCTG AGCGGCGAGC AGCAGGATGT CTCCATAGAC 
CTCACACCAC TTGCCCAGAG CGGAGGTTCA TCCTATATTT CAGATGGAAA AGAATATTTG 
TTTTATTTGA ATGTCTGTGG AGAAACTGAA ATACAGTTCT GTAATAAAAA ACAAGCTGCA 
GTTTGCCAAG TGAAAAAGAG CGATACCTCT CAAGTCAAAG CAGCAGGAAG ATACCACAAT 
CAGACCCTCC GATATTCGGA TGGAGACCTC ACCTTGATAT ATTTTGGAGG TGATGAATGC 
AGCTCAGGGT TTCAGCGGAT GAGCGTCATA AACTTTGAGT GCAATAAAAC CGCAGGTAAC 
GATGGGAAAG GAACTCCTGT ATTCACAGGG GAGGTTGACT GCACCTACTT CTTCACATGG 
GACACGGAAT ACGCCTGTGT TAAGGAGAAG GAAGACCTCC TCTGCGGTGC CACCGACGGG 
AAGAAGCGCT ATGACCTGTC CGCGCTGGTC CGCCATGCAG AACCAGAGCA GAATTGGGAA 
GCTGTGGATG GCAGTCAGAC GGAAACAGAG AAGAAGCATT TTTTCATTAA TATTTGTCAC 
AGAGTGCTGC AGGAAGGCAA GGCACGAGGG TGTCCCGAGG ACGCGGCAGT GTGTGCAGTG 
GATAAAAATG GAAGTAAAAA TCTGGGAAAA TTTATTTCCT CTCCCATGAA AGAGAAAGGA 
AACATTCAAC TCTCTTATTC AGATGGTGAT GATTGTGGTC ATGGCAAGAA AATTAAAACT 
AATATCACAC TTGTATGCAA GCCAGGTGAT CTGGAAAGTG CACCAGTGTT GAGAACTTCT 
GGGGAAGGCG GTTGCTTTTA TGAGTTTGAG TGGCACACAG CTGCGGCCTG TGTGCTGTCT 
AAGACAGAAG GGGAGAACTG CACGGTCTTT GACTCCCAGG CAGGGTTTTC TTTTGACTTA 
TCACCTCTCA CAAAGAAAAA TGGTGCCTAT AAAGTTGAGA CAAAGAAGTA TGACTTTTAT 
ATAAATGTGT GTGGCCCGGT GTCTGTGAGC CCCTGTCAGC CAGACTCAGG AGCCTGCCAG 
GTGGCAAAAA GTGATGAGAA GACTTGGAAC TTGGGTCTGA GTAATGCGAA GCTTTCATAT 
TATGATGGGA TGATCCAACT GAACTACAGA GGCGGCACAC CCTATAACAA TGAAAGACAC 
ACACCGAGAG CTACGCTCAT CACCTTTCTC TGTGATCGAG ACGCGGGAGT GGGCTTCCCT 
GAATATCAGG AAGAGGATAA CTCCACCTAC AACTTCCGGT GGTACACCAG CTATGCCTGC 
CCGGAGGAGC CCCTGGAATG CGTAGTGACC GACCCCTCCA CGCTGGAGCA GTACGACCTC 
TCCAGTCTGG CAAAATCTGA AGGTGGCCTT GGAGGAAACT GGTATGCCAT GGACAACTCA 
GGGGAACATG TCACGTGGAG GAAATACTAC ATTAACGTGT GTCGGCCTCT GAATCCAGTG 
CCGGGCTGCA ACCGATATGC ATCGGCTTGC CAGATGAAGT ATGAAAAAGA TCAGGGCTCC 
TTCACTGAAG TGGTTTCCAT CAGTAACTTG GGAATGGCAA AGACCGGCCC GGTGGTTGAG 
GACAGCGGCA GCCTCCTTCT GGAATACGTG AATGGGTCGG CCTGCACCAC CAGCGATGGC 
AGACAGACCA CATATACCAC GAGGATCCAT CTCGTCTGCT CCAGGGGCAG GCTGAACAGC 
CACCCCATCT TTTCTCTCAA CTGGGAGTGT GTGGTCAGTT TCCTGTGGAA CACAGAGGCT 
GCCTGTCCCA TTCAGACAAC GACGGATACA GACCAGGCTT GCTCTATAAG GGATCCCAAC 
AGTGGATTTG TGTTTAATCT TAATCCGCTA AACAGTTCGC AAGGATATAA CGTCTCTGGC 
ATTGGGAAGA TTTTTATGTT TAATGTCTGC GGCACAATGC CTGTCTGTGG GACCATCCTG 
GGAAAACCTG CTTCTGGCTG TGAGGCAGAA ACCCAAACTG AAGAGCTCAA GAATTGGAAG 
CCAGCAAGGC CAGTCGGAAT TGAGAAAAGC CTCCAGCTGT CCACAGAGGG CTTCATCACT 
CTGACCTACA AAGGGCCTCT CTCTGCCAAA GGTACCGCTG ATGCTTTTAT CGTCCGCTTT 
GTTTGCAATG ATGATGTTTA CTCAGGGCCC CTCAAATTCC TGCATCAAGA TATCGACTCT 
GGGCAAGGGA TCCGAAACAC TTACTTTGAG TTTGAAACCG CGTTGGCCTG TGTTCCTTCT 
CCAGTGGACT GCCAAGTCAC CGACCTGGCT GGAAATGAGT ACGACCTGAC TGGCCTAAGC 
ACAGTCAGGA AACCTTGGAC GGCTGTTGAC ACCTCTGTCG ATGGGAGAAA GAGGACTTTC 
TATTTGAGCG TTTGCAATCC TCTCCCTTAC ATTCCTGGAT GCCAGGGCAG CGCAGTGGGG 
TCTTGCTTAG TGTCAGAAGG CAATAGCTGG AATCTGGGTG TGGTGCAGAT GAGTCCCCAA 
GCCGCGGCGA ATGGATCTTT GAGCATCATG TATGTCAACG GTGACAAGTG TGGGAACCAG 
CGCTTCTCCA CCAGGATCAC GTTTGAGTGT GCTCAGATAT CGGGCTCACC AGCATTTCAG 
CTTCAGGATG GTTGTGAGTA CGTGTTTATC TGGAGAACTG TGGAAGCCTG TCCCGTTGTC 
AGAGTGGAAG GGGACAACTG TGAGGTGAAA GACCCAAGGC ATGGCAACTT GTATGACCTG 
AAGCCCCTGG GCCTCAACGA CACCATCGTG AGCGCTGGCG AATACACTTA TTACTTCCGG 
GTCTGTGGGA AGCTTTCCTC AGACGTCTGC CCCACAAGTG ACAAGTCCAA GGTGGTCTCC 
TCATGTCAGG AAAAGCGGGA ACCGCAGGGA TTTCACAAAG TGGCAGGTCT CCTGACTCAG 
AAGCTAACTT ATGAAAATGG CTTGTTAAAA ATGAACTTCA CGGGGGGGGA CACTTGCCAT 
AAGGTTTATC AGCGCTCCAC AGCCATCTTC TTCTACTGTG ACCGCGGCAC CCAGCGGCCA 
GTATTTCTAA AGGAGACTTC AGATTGTTCC TACTTGTTTG AGTGGCGAAC GCAGTATGCC 
TGCCCACCTT TCGATCTGAC TGAATGTTCA TTCAAAGATG GGGCTGGCAA CTCCTTCGAC 
CTCTCGTCCC TGTCAAGGTA CAGTGACAAC TGGGAAGCCA TCACTGGGAC GGGGGACCCG 
GAGCACTACC TCATCAATGT CTGCAAGTCT CTGGCCCCGC AGGCTGGCAC TGAGCCGTGC 
CCTCCAGAAG CAGCCGCGTG TCTGCTGGGT GGCTCCAAGC CCGTGAACCT CGGCAGGGTA 
AGGGACGGAC CTCAGTGGAG AGATGGCATA ATTGTCCTGA AATACGTTGA TGGCGACTTA 
TGTCCAGATG GGATTCGGAA AAAGTCAACC ACCATCCGAT TCACCTGCAG CGAGAGCCAA 
GTGAACTCCA GGCCCATGTT CATCAGCGCC GTGGAGGACT GTGAGTACAC CTTTGCCTGG 
CCCACAGCCA CAGCCTGTCC CATGAAGAGC AACGAGCATG ATGACTGCCA GGTCACCAAC 
CCAAGCACAG GACACCTGTT TGATCTGAGC TCCTTAAGTG GCAGGGCGGG ATTCACAGCT 
GCTTACAGCG AGAAGGGGTT GGTTTACATG AGCATCTGTG GGGAGAATGA AAACTGCCCT 
CCTGGCGTGG GGGCCTGCTT TGGACAGACC AGGATTAGCG TGGGCAAGGC CAACAAGAGG 
CTGAGATACG TGGACCAGGT CCTGCAGCTG GTGTACAAGG ATGGGTCCCC TTGTCCCTCC 
AAATCCGGCC TGAGCTATAA GAGTGTGATC AGTTTCGTGT GCAGGCCTGA GGCCGGGCCA 
ACCAATAGGC CCATGCTCAT CTCCCTGGAC AAGCAGACAT GCACTCTCTT CTTCTCCTGG 
CACACGCCGC TGGCCTGCGA GCAAGCGACC GAATGTTCCG TGAGGAATGG AAGCTCTATT 
GTTGACTTGT CTCCCCTTAT TCATCGCACT GGTGGTTATG AGGCTTATGA TGAGAGTGAG 
GATGATGCCT CCGATACCAA CCCTGATTTC TACATCAATA TTTGTCAGCC ACTAAATCCC 
ATGCACGGAG TGCCCTGTCC TGCCGGAGCC GCTGTGTGCA AAGTTCCTAT TGATGGTCCC 
CCCATAGATA TCGGCCGGGT AGCAGGACCA CCAATACTCA ATCCAATAGC AAATGAGATT 
TACTTGAATT TTGAAAGCAG TACTCCTTGC TTAGCGGACA AGCATTTCAA CTACACCTCG 
CTCATCGCGT TTCACTGTAA GAGAGGTGTG AGCATGGGAA CGCCTAAGCT GTTAAGGACC 
AGCGAGTGCG ACTTTGTGTT CGAATGGGAG ACTCCTGTCG TCTGTCCTGA TGAAGTGAGG 
ATGGATGGCT GTACCCTGAC AGATGAGCAG CTCCTCTACA GCTTCAACTT GTCCAGCCTT 
TCCACGAGCA CCTTTAAGGT GACTCGCGAC TCGCGCACCT ACAGCGTTGG GGTGTGCACC 
TTTGCAGTCG GGCCAGAACA AGGAGGCTGT AAGGACGGAG GAGTCTGTCT GCTCTCAGGC 
ACCAAGGGGG CATCCTTTGG ACGGCTGCAA TCAATGAAAC TGGATTACAG GCACCAGGAT 
GAAGCGGTCG TTTTAAGTTA CGTGAATGGT GATCGTTGCC CTCCAGAAAC CGATGACGGC 
GTCCCCTGTG TCTTCCCCTT CATATTCAAT GGGAAGAGCT ACGAGGAGTG CATCATAGAG 
AGCAGGGCGA AGCTGTGGTG TAGCACAACT GCGGACTACG ACAGAGACCA CGAGTGGGGC 
TTCTGCAGAC ACTCAAACAG CTACCGGACA TCCAGCATCA TATTTAAGTG TGATGAAGAT 
GAGGACATTG GGAGGCCACA AGTCTTCAGT GAAGTGCGTG GGTGTGATGT GACATTTGAG 
TGGAAAACAA AAGTTGTCTG CCCTCCAAAG AAGTTGGAGT GCAAATTCGT CCAGAAACAC 
AAAACCTACG ACCTGCGGCT GCTCTCCTCT CTCACCGGGT CCTGGTCCCT GGTCCACAAC 
GGAGTCTCGT ACTATATAAA TCTGTGCCAG AAAATATATA AAGGGCCCCT GGGCTGCTCT 
GAAAGGGCCA GCATTTGCAG AAGGACCACA ACTGGTGACG TCCAGGTCCT GGGACTCGTT 
CACACGCAGA AGCTGGGTGT CATAGGTGAC AAAGTTGTTG TCACGTACTC CAAAGGTTAT 
CCGTGTGGTG GAAATAAGAC CGCATCCTCC GTGATAGAAT TGACCTGTAC AAAGACGGTG 
GGCAGACCTG CATTCAAGAG GTTTGATATC GACAGCTGCA CTTACTACTT CAGCTGGGAC 
TCCCGGGCTG CCTGCGCCGT GAAGCCTCAG GAGGTGCAGA TGGTGAATGG GACCATCACC 
AACCCTATAA ATGGCAAGAG CTTCAGCCTC GGAGATATTT ATTTTAAGCT GTTCAGAGCC 
TCTGGGGACA TGAGGACCAA TGGGGACAAC TACCTGTATG AGATCCAACT TTCCTCCATC 
ACAAGCTCCA GAAACCCGGC GTGCTCTGGA GCCAACATAT GCCAGGTGAA GCCCAACGAT 
CAGCACTTCA GTCGGAAAGT TGGAACCTCT GACAAGACCA AGTACTACCT TCAAGACGGC 
GATCTCGATG TCGTGTTTGC CTCTTCCTCT AAGTGCGGAA AGGATAAGAC CAAGTCTGTT 
TCTTCCACCA TCTTCTTCCA CTGTGACCCT CTGGTGGAGG ACGGGATCCC CGAGTTCAGT 
CACGAGACTG CCGACTGCCA GTACCTCTTC TCTTGGTACA CCTCAGCCGT GTGTCCTCTG 
GGGGTGGGCT TTGACAGCGA GAATCCCGGG GACGACGGGC AGATGCACAA GGGGCTGTCA 
GAACGGAGCC AGGCAGTCGG CGCGGTGCTC AGCCTGCTGC TGGTGGCGCT CACCTGCTGC 
CTGCTGGCCC TGTTGCTCTA CAAGAAGGAG AGGAGGGAAA CAGTGATAAG TAAGCTGACC 
ACTTGCTGTA GGAGAAGTTC CAACGTGTCC TACAAATACT CAAAGGTGAA TAAGGAAGAA 
GAGACAGATG AGAATGAAAC AGAGTGGCTG ATGGAAGAGA TCCAGCTGCC TCCTCCACGG 
CAGGGAAAGG AAGGGCAGGA GAACGGCCAT ATTACCACCA AGTCAGTGAA AGCCCTCAGC 
TCCCTGCATG GGGATGACCA GGACAGTGAG GATGAGGTTC TGACCATCCC AGAGGTGAAA 
GTTCACTCGG GCAGGGGAGC TGGGGCAGAG AGCTCCCACC CAGTGAGAAA CGCACAGAGC 
AATGCCCTTC AGGAGCGTGA GGACGATAGG GTGGGGCTGG TCAGGGGTGA GAAGGCGAGG 
AAAGGGAAGT CCAGCTCTGC ACAGCAGAAG ACAGTGAGCT CCACCAAGCT GGTGTCCTTC 
CATGACGACA GCGACGAGGA CCTCTTACAC ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_000867.2

Translation

MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAPFPELCSYTWEAVDTKNNVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQGTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTLRDPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYLFYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDECSSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDGKKRYDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVLSKTEGENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFYINVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERHTPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDLSSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGSFTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNSHPIFSLNWECVVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSGIGKIFMFNVCGTMPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFITLTYKGPLSAKGTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPSPVDCQVTDLAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVGSCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQLQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFRVCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCHKVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNSFDLSSLSRYSDNWEAITGTGDPEHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVNLGRVRDGPQWRDGIIVLKYVDGDLCPDGIRKKSTTIRFTCSESQVNSRPMFISAVEDCEYTFAWPTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYDESEDDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEIYLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVRMDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSGTKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDGVPCVFPFIFNGKSYEECIIESRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDEDEDIGRPQVFSEVRGCDVTFEWKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQKIYKGPLGCSERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTVGRPAFKRFDIDSCTYYFSWDSRAACAVKPQEVQMVNGTITNPINGKSFSLGDIYFKLFRASGDMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDQHFSRKVGTSDKTKYYLQDGDLDVVFASSSKCGKDKTKSVSSTIFFHCDPLVEDGIPEFSHETADCQYLFSWYTSAVCPLGVGFDSENPGDDGQMHKGLSERSQAVGAVLSLLLVALTCCLLALLLYKKERRETVISKLTTCCRRSSNVSYKYSKVNKEEETDENETEWLMEEIQLPPPRQGKEGQENGHITTKSVKALSSLHGDDQDSEDEVLTIPEVKVHSGRGAGAESSHPVRNAQSNALQEREDDRVGLVRGEKARKGKSSSAQQKTVSSTKLVSFHDDSDEDLLHI

Target ORF information:

RefSeq Version	NM_000876.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens insulin-like growth factor 2 receptor (IGF2R), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000876.2

ORF Insert Sequence:

ATGGGGGCCG CCGCCGGCCG GAGCCCCCAC CTGGGGCCCG CGCCCGCCCG CCGCCCGCAG 
CGCTCTCTGC TCCTGCTGCA GCTGCTGCTG CTCGTCGCTG CCCCGGGGTC CACGCAGGCC 
CAGGCCGCCC CGTTCCCCGA GCTGTGCAGT TATACATGGG AAGCTGTTGA TACCAAAAAT 
AATGTACTTT ATAAAATCAA CATCTGTGGA AGTGTGGATA TTGTCCAGTG CGGGCCATCA 
AGTGCTGTTT GTATGCACGA CTTGAAGACA CGCACTTATC ATTCAGTGGG TGACTCTGTT 
TTGAGAAGTG CAACCAGATC TCTCCTGGAA TTCAACACAA CAGTGAGCTG TGACCAGCAA 
GGCACAAATC ACAGAGTCCA GAGCAGCATT GCCTTCCTGT GTGGGAAAAC CCTGGGAACT 
CCTGAATTTG TAACTGCAAC AGAATGTGTG CACTACTTTG AGTGGAGGAC CACTGCAGCC 
TGCAAGAAAG ACATATTTAA AGCAAATAAG GAGGTGCCAT GCTATGTGTT TGATGAAGAG 
TTGAGGAAGC ATGATCTCAA TCCTCTGATC AAGCTTAGTG GTGCCTACTT GGTGGATGAC 
TCCGATCCGG ACACTTCTCT ATTCATCAAT GTTTGTAGAG ACATAGACAC ACTACGAGAC 
CCAGGTTCAC AGCTGCGGGC CTGTCCCCCC GGCACTGCCG CCTGCCTGGT AAGAGGACAC 
CAGGCGTTTG ATGTTGGCCA GCCCCGGGAC GGACTGAAGC TGGTGCGCAA GGACAGGCTT 
GTCCTGAGTT ACGTGAGGGA AGAGGCAGGA AAGCTAGACT TTTGTGATGG TCACAGCCCT 
GCGGTGACTA TTACATTTGT TTGCCCGTCG GAGCGGAGAG AGGGCACCAT TCCCAAACTC 
ACAGCTAAAT CCAACTGCCG CTATGAAATT GAGTGGATTA CTGAGTATGC CTGCCACAGA 
GATTACCTGG AAAGTAAAAC TTGTTCTCTG AGCGGCGAGC AGCAGGATGT CTCCATAGAC 
CTCACACCAC TTGCCCAGAG CGGAGGTTCA TCCTATATTT CAGATGGAAA AGAATATTTG 
TTTTATTTGA ATGTCTGTGG AGAAACTGAA ATACAGTTCT GTAATAAAAA ACAAGCTGCA 
GTTTGCCAAG TGAAAAAGAG CGATACCTCT CAAGTCAAAG CAGCAGGAAG ATACCACAAT 
CAGACCCTCC GATATTCGGA TGGAGACCTC ACCTTGATAT ATTTTGGAGG TGATGAATGC 
AGCTCAGGGT TTCAGCGGAT GAGCGTCATA AACTTTGAGT GCAATAAAAC CGCAGGTAAC 
GATGGGAAAG GAACTCCTGT ATTCACAGGG GAGGTTGACT GCACCTACTT CTTCACATGG 
GACACGGAAT ACGCCTGTGT TAAGGAGAAG GAAGACCTCC TCTGCGGTGC CACCGACGGG 
AAGAAGCGCT ATGACCTGTC CGCGCTGGTC CGCCATGCAG AACCAGAGCA GAATTGGGAA 
GCTGTGGATG GCAGTCAGAC GGAAACAGAG AAGAAGCATT TTTTCATTAA TATTTGTCAC 
AGAGTGCTGC AGGAAGGCAA GGCACGAGGG TGTCCCGAGG ACGCGGCAGT GTGTGCAGTG 
GATAAAAATG GAAGTAAAAA TCTGGGAAAA TTTATTTCCT CTCCCATGAA AGAGAAAGGA 
AACATTCAAC TCTCTTATTC AGATGGTGAT GATTGTGGTC ATGGCAAGAA AATTAAAACT 
AATATCACAC TTGTATGCAA GCCAGGTGAT CTGGAAAGTG CACCAGTGTT GAGAACTTCT 
GGGGAAGGCG GTTGCTTTTA TGAGTTTGAG TGGCACACAG CTGCGGCCTG TGTGCTGTCT 
AAGACAGAAG GGGAGAACTG CACGGTCTTT GACTCCCAGG CAGGGTTTTC TTTTGACTTA 
TCACCTCTCA CAAAGAAAAA TGGTGCCTAT AAAGTTGAGA CAAAGAAGTA TGACTTTTAT 
ATAAATGTGT GTGGCCCGGT GTCTGTGAGC CCCTGTCAGC CAGACTCAGG AGCCTGCCAG 
GTGGCAAAAA GTGATGAGAA GACTTGGAAC TTGGGTCTGA GTAATGCGAA GCTTTCATAT 
TATGATGGGA TGATCCAACT GAACTACAGA GGCGGCACAC CCTATAACAA TGAAAGACAC 
ACACCGAGAG CTACGCTCAT CACCTTTCTC TGTGATCGAG ACGCGGGAGT GGGCTTCCCT 
GAATATCAGG AAGAGGATAA CTCCACCTAC AACTTCCGGT GGTACACCAG CTATGCCTGC 
CCGGAGGAGC CCCTGGAATG CGTAGTGACC GACCCCTCCA CGCTGGAGCA GTACGACCTC 
TCCAGTCTGG CAAAATCTGA AGGTGGCCTT GGAGGAAACT GGTATGCCAT GGACAACTCA 
GGGGAACATG TCACGTGGAG GAAATACTAC ATTAACGTGT GTCGGCCTCT GAATCCAGTG 
CCGGGCTGCA ACCGATATGC ATCGGCTTGC CAGATGAAGT ATGAAAAAGA TCAGGGCTCC 
TTCACTGAAG TGGTTTCCAT CAGTAACTTG GGAATGGCAA AGACCGGCCC GGTGGTTGAG 
GACAGCGGCA GCCTCCTTCT GGAATACGTG AATGGGTCGG CCTGCACCAC CAGCGATGGC 
AGACAGACCA CATATACCAC GAGGATCCAT CTCGTCTGCT CCAGGGGCAG GCTGAACAGC 
CACCCCATCT TTTCTCTCAA CTGGGAGTGT GTGGTCAGTT TCCTGTGGAA CACAGAGGCT 
GCCTGTCCCA TTCAGACAAC GACGGATACA GACCAGGCTT GCTCTATAAG GGATCCCAAC 
AGTGGATTTG TGTTTAATCT TAATCCGCTA AACAGTTCGC AAGGATATAA CGTCTCTGGC 
ATTGGGAAGA TTTTTATGTT TAATGTCTGC GGCACAATGC CTGTCTGTGG GACCATCCTG 
GGAAAACCTG CTTCTGGCTG TGAGGCAGAA ACCCAAACTG AAGAGCTCAA GAATTGGAAG 
CCAGCAAGGC CAGTCGGAAT TGAGAAAAGC CTCCAGCTGT CCACAGAGGG CTTCATCACT 
CTGACCTACA AAGGGCCTCT CTCTGCCAAA GGTACCGCTG ATGCTTTTAT CGTCCGCTTT 
GTTTGCAATG ATGATGTTTA CTCAGGGCCC CTCAAATTCC TGCATCAAGA TATCGACTCT 
GGGCAAGGGA TCCGAAACAC TTACTTTGAG TTTGAAACCG CGTTGGCCTG TGTTCCTTCT 
CCAGTGGACT GCCAAGTCAC CGACCTGGCT GGAAATGAGT ACGACCTGAC TGGCCTAAGC 
ACAGTCAGGA AACCTTGGAC GGCTGTTGAC ACCTCTGTCG ATGGGAGAAA GAGGACTTTC 
TATTTGAGCG TTTGCAATCC TCTCCCTTAC ATTCCTGGAT GCCAGGGCAG CGCAGTGGGG 
TCTTGCTTAG TGTCAGAAGG CAATAGCTGG AATCTGGGTG TGGTGCAGAT GAGTCCCCAA 
GCCGCGGCGA ATGGATCTTT GAGCATCATG TATGTCAACG GTGACAAGTG TGGGAACCAG 
CGCTTCTCCA CCAGGATCAC GTTTGAGTGT GCTCAGATAT CGGGCTCACC AGCATTTCAG 
CTTCAGGATG GTTGTGAGTA CGTGTTTATC TGGAGAACTG TGGAAGCCTG TCCCGTTGTC 
AGAGTGGAAG GGGACAACTG TGAGGTGAAA GACCCAAGGC ATGGCAACTT GTATGACCTG 
AAGCCCCTGG GCCTCAACGA CACCATCGTG AGCGCTGGCG AATACACTTA TTACTTCCGG 
GTCTGTGGGA AGCTTTCCTC AGACGTCTGC CCCACAAGTG ACAAGTCCAA GGTGGTCTCC 
TCATGTCAGG AAAAGCGGGA ACCGCAGGGA TTTCACAAAG TGGCAGGTCT CCTGACTCAG 
AAGCTAACTT ATGAAAATGG CTTGTTAAAA ATGAACTTCA CGGGGGGGGA CACTTGCCAT 
AAGGTTTATC AGCGCTCCAC AGCCATCTTC TTCTACTGTG ACCGCGGCAC CCAGCGGCCA 
GTATTTCTAA AGGAGACTTC AGATTGTTCC TACTTGTTTG AGTGGCGAAC GCAGTATGCC 
TGCCCACCTT TCGATCTGAC TGAATGTTCA TTCAAAGATG GGGCTGGCAA CTCCTTCGAC 
CTCTCGTCCC TGTCAAGGTA CAGTGACAAC TGGGAAGCCA TCACTGGGAC GGGGGACCCG 
GAGCACTACC TCATCAATGT CTGCAAGTCT CTGGCCCCGC AGGCTGGCAC TGAGCCGTGC 
CCTCCAGAAG CAGCCGCGTG TCTGCTGGGT GGCTCCAAGC CCGTGAACCT CGGCAGGGTA 
AGGGACGGAC CTCAGTGGAG AGATGGCATA ATTGTCCTGA AATACGTTGA TGGCGACTTA 
TGTCCAGATG GGATTCGGAA AAAGTCAACC ACCATCCGAT TCACCTGCAG CGAGAGCCAA 
GTGAACTCCA GGCCCATGTT CATCAGCGCC GTGGAGGACT GTGAGTACAC CTTTGCCTGG 
CCCACAGCCA CAGCCTGTCC CATGAAGAGC AACGAGCATG ATGACTGCCA GGTCACCAAC 
CCAAGCACAG GACACCTGTT TGATCTGAGC TCCTTAAGTG GCAGGGCGGG ATTCACAGCT 
GCTTACAGCG AGAAGGGGTT GGTTTACATG AGCATCTGTG GGGAGAATGA AAACTGCCCT 
CCTGGCGTGG GGGCCTGCTT TGGACAGACC AGGATTAGCG TGGGCAAGGC CAACAAGAGG 
CTGAGATACG TGGACCAGGT CCTGCAGCTG GTGTACAAGG ATGGGTCCCC TTGTCCCTCC 
AAATCCGGCC TGAGCTATAA GAGTGTGATC AGTTTCGTGT GCAGGCCTGA GGCCGGGCCA 
ACCAATAGGC CCATGCTCAT CTCCCTGGAC AAGCAGACAT GCACTCTCTT CTTCTCCTGG 
CACACGCCGC TGGCCTGCGA GCAAGCGACC GAATGTTCCG TGAGGAATGG AAGCTCTATT 
GTTGACTTGT CTCCCCTTAT TCATCGCACT GGTGGTTATG AGGCTTATGA TGAGAGTGAG 
GATGATGCCT CCGATACCAA CCCTGATTTC TACATCAATA TTTGTCAGCC ACTAAATCCC 
ATGCACGGAG TGCCCTGTCC TGCCGGAGCC GCTGTGTGCA AAGTTCCTAT TGATGGTCCC 
CCCATAGATA TCGGCCGGGT AGCAGGACCA CCAATACTCA ATCCAATAGC AAATGAGATT 
TACTTGAATT TTGAAAGCAG TACTCCTTGC TTAGCGGACA AGCATTTCAA CTACACCTCG 
CTCATCGCGT TTCACTGTAA GAGAGGTGTG AGCATGGGAA CGCCTAAGCT GTTAAGGACC 
AGCGAGTGCG ACTTTGTGTT CGAATGGGAG ACTCCTGTCG TCTGTCCTGA TGAAGTGAGG 
ATGGATGGCT GTACCCTGAC AGATGAGCAG CTCCTCTACA GCTTCAACTT GTCCAGCCTT 
TCCACGAGCA CCTTTAAGGT GACTCGCGAC TCGCGCACCT ACAGCGTTGG GGTGTGCACC 
TTTGCAGTCG GGCCAGAACA AGGAGGCTGT AAGGACGGAG GAGTCTGTCT GCTCTCAGGC 
ACCAAGGGGG CATCCTTTGG ACGGCTGCAA TCAATGAAAC TGGATTACAG GCACCAGGAT 
GAAGCGGTCG TTTTAAGTTA CGTGAATGGT GATCGTTGCC CTCCAGAAAC CGATGACGGC 
GTCCCCTGTG TCTTCCCCTT CATATTCAAT GGGAAGAGCT ACGAGGAGTG CATCATAGAG 
AGCAGGGCGA AGCTGTGGTG TAGCACAACT GCGGACTACG ACAGAGACCA CGAGTGGGGC 
TTCTGCAGAC ACTCAAACAG CTACCGGACA TCCAGCATCA TATTTAAGTG TGATGAAGAT 
GAGGACATTG GGAGGCCACA AGTCTTCAGT GAAGTGCGTG GGTGTGATGT GACATTTGAG 
TGGAAAACAA AAGTTGTCTG CCCTCCAAAG AAGTTGGAGT GCAAATTCGT CCAGAAACAC 
AAAACCTACG ACCTGCGGCT GCTCTCCTCT CTCACCGGGT CCTGGTCCCT GGTCCACAAC 
GGAGTCTCGT ACTATATAAA TCTGTGCCAG AAAATATATA AAGGGCCCCT GGGCTGCTCT 
GAAAGGGCCA GCATTTGCAG AAGGACCACA ACTGGTGACG TCCAGGTCCT GGGACTCGTT 
CACACGCAGA AGCTGGGTGT CATAGGTGAC AAAGTTGTTG TCACGTACTC CAAAGGTTAT 
CCGTGTGGTG GAAATAAGAC CGCATCCTCC GTGATAGAAT TGACCTGTAC AAAGACGGTG 
GGCAGACCTG CATTCAAGAG GTTTGATATC GACAGCTGCA CTTACTACTT CAGCTGGGAC 
TCCCGGGCTG CCTGCGCCGT GAAGCCTCAG GAGGTGCAGA TGGTGAATGG GACCATCACC 
AACCCTATAA ATGGCAAGAG CTTCAGCCTC GGAGATATTT ATTTTAAGCT GTTCAGAGCC 
TCTGGGGACA TGAGGACCAA TGGGGACAAC TACCTGTATG AGATCCAACT TTCCTCCATC 
ACAAGCTCCA GAAACCCGGC GTGCTCTGGA GCCAACATAT GCCAGGTGAA GCCCAACGAT 
CAGCACTTCA GTCGGAAAGT TGGAACCTCT GACAAGACCA AGTACTACCT TCAAGACGGC 
GATCTCGATG TCGTGTTTGC CTCTTCCTCT AAGTGCGGAA AGGATAAGAC CAAGTCTGTT 
TCTTCCACCA TCTTCTTCCA CTGTGACCCT CTGGTGGAGG ACGGGATCCC CGAGTTCAGT 
CACGAGACTG CCGACTGCCA GTACCTCTTC TCTTGGTACA CCTCAGCCGT GTGTCCTCTG 
GGGGTGGGCT TTGACAGCGA GAATCCCGGG GACGACGGGC AGATGCACAA GGGGCTGTCA 
GAACGGAGCC AGGCAGTCGG CGCGGTGCTC AGCCTGCTGC TGGTGGCGCT CACCTGCTGC 
CTGCTGGCCC TGTTGCTCTA CAAGAAGGAG AGGAGGGAAA CAGTGATAAG TAAGCTGACC 
ACTTGCTGTA GGAGAAGTTC CAACGTGTCC TACAAATACT CAAAGGTGAA TAAGGAAGAA 
GAGACAGATG AGAATGAAAC AGAGTGGCTG ATGGAAGAGA TCCAGCTGCC TCCTCCACGG 
CAGGGAAAGG AAGGGCAGGA GAACGGCCAT ATTACCACCA AGTCAGTGAA AGCCCTCAGC 
TCCCTGCATG GGGATGACCA GGACAGTGAG GATGAGGTTC TGACCATCCC AGAGGTGAAA 
GTTCACTCGG GCAGGGGAGC TGGGGCAGAG AGCTCCCACC CAGTGAGAAA CGCACAGAGC 
AATGCCCTTC AGGAGCGTGA GGACGATAGG GTGGGGCTGG TCAGGGGTGA GAAGGCGAGG 
AAAGGGAAGT CCAGCTCTGC ACAGCAGAAG ACAGTGAGCT CCACCAAGCT GGTGTCCTTC 
CATGACGACA GCGACGAGGA CCTCTTACAC ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse.
Human molecular genetics13(19)2233-45(2004 Oct)
Vu TH,Li T,Hoffman AR

Functional polymorphism in the parental imprinting of the human IGF2R gene.
Biochemical and biophysical research communications197(2)747-54(1993 Dec)
Xu Y,Goodyer CG,Deal C,Polychronakos C

The insulin-like growth factor type-2 receptor gene is imprinted in the mouse but not in humans.
Nature genetics5(1)74-8(1993 Sep)
Kalscheuer VM,Mariman EC,Schepens MT,Rehder H,Ropers HH

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IGF2R cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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