Gene Symbol | IFNAR2 |
Entrez Gene ID | 3455 |
Full Name | interferon alpha and beta receptor subunit 2 |
Synonyms | IFN-R,IFN-alpha-REC,IFNABR,IFNARB,IMD45 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | {Hepatitis B virus, susceptibility to}, 610424 (3); ?Immunodeficiency 45, 616669 (3) |