LRIT3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRIT3
Entrez Gene ID	345193
Full Name	leucine rich repeat, Ig-like and transmembrane domains 3
Synonyms	CSNB1F,FIGLER4
General protein information	Preferred Names leucine rich repeat, Ig-like and transmembrane domains 3 Names leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 fibronectin type III, immunoglobulin and leucine rich repeat domains 4 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q25
Summary	This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F. [provided by RefSeq, May 2013].
Disorder MIM:	615004
Disorder Html:	Night blindness, congenital stationary (complete), 1F, autosomal recessive, 615058 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_198506.5	NP_940908.3	leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 precursor
XM_017008167.1	XP_016863656.1	leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 isoform X1
XM_017008168.1	XP_016863657.1	leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 isoform X2
NM_198506.4	NP_940908.3	leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LRIT3	NP_940908.3
Pan troglodytes (chimpanzee)	LRIT3	XP_001139031.3
Xenopus tropicalis (tropical clawed frog)	lrit3	XP_002934296.1
Rattus norvegicus (Norway rat)	Lrit3	XP_006232069.1
Danio rerio (zebrafish)	lrit3a	NP_001122166.1
	LRIT3	XP_001088511.1
Bos taurus (cattle)	LRIT3	NP_001178443.1
Gallus gallus (chicken)	LRIT3	XP_420649.4
Canis lupus familiaris (dog)	LRIT3	XP_853150.3
Mus musculus (house mouse)	Lrit3	NP_001274153.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutation screening of the LRIT3, CABP4, and GPR179 genes in Chinese patients with Schubert-Bornschein congenital stationary night blindness.
Dan H, Song X, Li J, Xing Y, Li T
Ophthalmic genetics38(3)206-210(2017 May-Jun)

LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells.
Neuill? M, Cao Y, Caplette R, Guerrero-Given D, Thomas C, Kamasawa N, Sahel JA, Hamel CP, Audo I, Picaud S, Martemyanov KA, Zeitz C
Investigative ophthalmology & visual science58(3)1768-1778(2017 03)

Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness.
Zeitz C, Jacobson SG, Hamel CP, Bujakowska K, Neuill? M, Orhan E, Zanlonghi X, Lancelot ME, Michiels C, Schwartz SB, Bocquet B, , Antonio A, Audier C, Letexier M, Saraiva JP, Luu TD, Sennlaub F, Nguyen H, Poch O, Dollfus H, Lecompte O, Kohl S, Sahel JA, Bhattacharya SS, Audo I
American journal of human genetics92(1)67-75(2013 Jan)

Leucine-rich repeat, immunoglobulin-like and transmembrane domain 3 (LRIT3) is a modulator of FGFR1.
Kim SD, Liu JL, Roscioli T, Buckley MF, Yagnik G, Boyadjiev SA, Kim J
FEBS letters586(10)1516-21(2012 May)

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP
Human molecular genetics19(12)2497-506(2010 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In this study, a novel compound heterozygous mutation, c.[1A>G]; [608G>T] (p.[0?]; p.[W203L]), was identified in the LRIT3 gene of a proband. No mutations were identified in the CABP4 or GPR179 gene.
Title: Mutation screening of the LRIT3, CABP4, and GPR179 genes in Chinese patients with Schubert-Bornschein congenital stationary night blindness.

LRIT3 is likely involved in coordination of the transsynaptic communication between cones and ON-BCs during synapse formation and
Title: LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells.

The exact role of this LRR protein in cCSNB remains to be elucidated.
Title: Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness.

Observational study of gene-disease association. (HuGE Navigator)
Title: A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.

The following LRIT3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRIT3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21649	NM_198506.5 Latest version!	Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu38919	XM_017008167.1 Latest version!	Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu95162	XM_017008168.1 Latest version!	Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu21649	NM_198506.4	Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRIT3 ( NM_198506.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_940908.3 Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), mRNA.

Price & Availability↑

CloneID	OHu21649
Clone ID Related Accession (Same CDS sequence)	NM_198506.5 , NM_198506.4
Accession Version	NM_198506.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2040bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC126283.3, JQ354981.1, DT932743.1, AC005509.1, BC104037.2 and BM665581.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_198506.4. Sequence Note: This RefSeq record was created from partial transcripts and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by orthologous alignment from mouse (NP_001192031.1). ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01820689, SAMN01820691 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000594814.6/ ENSP00000469759.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCATCTCT TTGCATGTCT GTGCATTGTC CTTAGCTTTT TGGAAGGAGT GGGCTGTTTG 
TGTCCTTCAC AGTGCACCTG TGATTATCAC GGCAGAAATG ACGGCTCAGG ATCAAGGTTG 
GTGCTATGTA ATGACATGGA TATGAACGAG CTGCCTACGA ACCTCCCCGT GGACACTGTG 
AAGCTTCGCA TAGAGAAGAC TGTCATCCGC AGAATCTCTG CGGAGGCCTT CTATTACCTG 
GTGGAGCTCC AGTATCTCTG GGTGACTTAC AATTCCGTGG CCAGCATTGA CCCCAGCAGC 
TTTTACAACC TGAAGCAACT GCATGAGTTG CGCTTGGATG GGAATTCTCT GGCTGCTTTC 
CCTTGGGCAT CTCTGCTGGA CATGCCCCTT CTGAGGACCC TGGACTTGCA CAATAACAAA 
ATAACCAGTG TGCCAAATGA GGCGCTCAGG TATCTGAAGA ACCTTGCCTA CTTGGATTTA 
TCAAGCAACA GACTCACCAC ATTGCCACCA GATTTCCTGG AGAGCTGGAC TCATTTAGTT 
TCAACACCTT CTGGAGTCCT GGACCTTTCC CCAAGCAGGA TTATTCTTGG TCTACAGGAC 
AATCCTTGGT TCTGTGACTG TCATATTTCC AAAATGATTG AGTTGTCAAA GGTCGTTGAC 
CCTGCTATAG TGCTTCTGGA TCCACTGATG ACTTGCAGTG AACCTGAGCG CCTCACAGGA 
ATTTTGTTTC AGCGGGCTGA ATTGGAGCAT TGTCTGAAAC CATCAGTGAT GACCTCAGCC 
ACCAAAATCA TGTCTGCTCT GGGCAGTAAT GTTCTACTGC GGTGTGATGC CACTGGCTTC 
CCCACCCCAC AGATCACATG GACCAGATCT GACAGCTCGC CAGTTAATTA TACAGTAATA 
CAAGAATCTC CAGAGGAAGG AGTCAGATGG TCCATAATGA GCTTGACAGG CATTTCTTCC 
AAAGACGCTG GGGATTACAA ATGTAAGGCC AAAAATCTGG CTGGGATGTC AGAAGCTGTG 
GTTACTGTGA CAGTGCTTGG CATTACCACA ACTCCAATAC CACCAGACAC TTCTGAAAGA 
ACTGGAGATC ATCCTGAGTG GGATGTCCAG CCGGGATCTG GAAGATCTAC ATCTGTATCT 
AGCGCATCAT CATATCTTTG GTCCTCTTCC TTCTCCCCCA CATCTTCTTT TTCTGCTTCT 
ACTTTGTCTC CTCCCTCTAC TGCTTCCTTC TCTTTATCTC CTTTCTCCTC CTCCACTGTT 
TCTTCAACCA CAACTCTGAG CACAAGCATC TCAGCAAGTA CCACCATGGC CAACAAGCGA 
TCATTCCAGC TCCACCAAGG TGGGAAAAGA AATTTAAAGG TGGCAAAGAA TGGAAGTAAG 
CTTCCTCCAG CCAGCACAAG TAAGAAAGAA GAGCTGGCAT TGTTGGATCA AACAATGCTT 
ACGGAGACAA ATGCCGCAAT AGAAAACCTC AGGGTGGTCA GTGAGACTAA AGAGAGTGTG 
ACATTGACGT GGAATATGAT CAACACCACA CATAACTCTG CAGTGACTGT GTTGTATTCC 
AAGTATGGTG GGAAGGACCT GCTGCTGTTG AATGCAGACT CCAGCAAGAA CCAAGTAACC 
ATAGATGGCT TGGAACCCGG TGGGCAATAC ATGGCCTGTG TCTGTCCAAA AGGAGTGCCT 
CCCCAGAAAG ACCAATGCAT CACCTTTTCT ACTGAAAGAG TTGAAGGAGA TGATTCTCAA 
TGGTCTCTCC TTCTCGTGGT GACCAGTACT GCCTGTGTTG TTATCTTACC ATTGATTTGT 
TTCTTGTTGT ACAAAGTTTG CAAACTGCAA TGTAAATCAG AACCTTTTTG GGAAGATGAT 
TTGGCAAAGG AGACTTATAT CCAATTTGAG ACCCTGTTTC CCAGGTCTCA AAGTGTAGGT 
GAGCTCTGGA CACGAAGCCA CAGGGATGAC TCAGAGAAAT TGCTGCTTTG TTCTAGGTCA 
AGTGTGGAAT CTCAGGTGAC TTTTAAAAGT GAAGGTTCCA GACCAGAGTA TTATTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940908.3
CDS	96..2135
Translation	MHLFACLCIVLSFLEGVGCLCPSQCTCDYHGRNDGSGSRLVLCNDMDMNELPTNLPVDTVKLRIEKTVIRRISAEAFYYLVELQYLWVTYNSVASIDPSSFYNLKQLHELRLDGNSLAAFPWASLLDMPLLRTLDLHNNKITSVPNEALRYLKNLAYLDLSSNRLTTLPPDFLESWTHLVSTPSGVLDLSPSRIILGLQDNPWFCDCHISKMIELSKVVDPAIVLLDPLMTCSEPERLTGILFQRAELEHCLKPSVMTSATKIMSALGSNVLLRCDATGFPTPQITWTRSDSSPVNYTVIQESPEEGVRWSIMSLTGISSKDAGDYKCKAKNLAGMSEAVVTVTVLGITTTPIPPDTSERTGDHPEWDVQPGSGRSTSVSSASSYLWSSSFSPTSSFSASTLSPPSTASFSLSPFSSSTVSSTTTLSTSISASTTMANKRSFQLHQGGKRNLKVAKNGSKLPPASTSKKEELALLDQTMLTETNAAIENLRVVSETKESVTLTWNMINTTHNSAVTVLYSKYGGKDLLLLNADSSKNQVTIDGLEPGGQYMACVCPKGVPPQKDQCITFSTERVEGDDSQWSLLLVVTSTACVVILPLICFLLYKVCKLQCKSEPFWEDDLAKETYIQFETLFPRSQSVGELWTRSHRDDSEKLLLCSRSSVESQVTFKSEGSRPEYYC

Target ORF information:

RefSeq Version	NM_198506.5
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198506.5

ORF Insert Sequence:

ATGCATCTCT TTGCATGTCT GTGCATTGTC CTTAGCTTTT TGGAAGGAGT GGGCTGTTTG 
TGTCCTTCAC AGTGCACCTG TGATTATCAC GGCAGAAATG ACGGCTCAGG ATCAAGGTTG 
GTGCTATGTA ATGACATGGA TATGAACGAG CTGCCTACGA ACCTCCCCGT GGACACTGTG 
AAGCTTCGCA TAGAGAAGAC TGTCATCCGC AGAATCTCTG CGGAGGCCTT CTATTACCTG 
GTGGAGCTCC AGTATCTCTG GGTGACTTAC AATTCCGTGG CCAGCATTGA CCCCAGCAGC 
TTTTACAACC TGAAGCAACT GCATGAGTTG CGCTTGGATG GGAATTCTCT GGCTGCTTTC 
CCTTGGGCAT CTCTGCTGGA CATGCCCCTT CTGAGGACCC TGGACTTGCA CAATAACAAA 
ATAACCAGTG TGCCAAATGA GGCGCTCAGG TATCTGAAGA ACCTTGCCTA CTTGGATTTA 
TCAAGCAACA GACTCACCAC ATTGCCACCA GATTTCCTGG AGAGCTGGAC TCATTTAGTT 
TCAACACCTT CTGGAGTCCT GGACCTTTCC CCAAGCAGGA TTATTCTTGG TCTACAGGAC 
AATCCTTGGT TCTGTGACTG TCATATTTCC AAAATGATTG AGTTGTCAAA GGTCGTTGAC 
CCTGCTATAG TGCTTCTGGA TCCACTGATG ACTTGCAGTG AACCTGAGCG CCTCACAGGA 
ATTTTGTTTC AGCGGGCTGA ATTGGAGCAT TGTCTGAAAC CATCAGTGAT GACCTCAGCC 
ACCAAAATCA TGTCTGCTCT GGGCAGTAAT GTTCTACTGC GGTGTGATGC CACTGGCTTC 
CCCACCCCAC AGATCACATG GACCAGATCT GACAGCTCGC CAGTTAATTA TACAGTAATA 
CAAGAATCTC CAGAGGAAGG AGTCAGATGG TCCATAATGA GCTTGACAGG CATTTCTTCC 
AAAGACGCTG GGGATTACAA ATGTAAGGCC AAAAATCTGG CTGGGATGTC AGAAGCTGTG 
GTTACTGTGA CAGTGCTTGG CATTACCACA ACTCCAATAC CACCAGACAC TTCTGAAAGA 
ACTGGAGATC ATCCTGAGTG GGATGTCCAG CCGGGATCTG GAAGATCTAC ATCTGTATCT 
AGCGCATCAT CATATCTTTG GTCCTCTTCC TTCTCCCCCA CATCTTCTTT TTCTGCTTCT 
ACTTTGTCTC CTCCCTCTAC TGCTTCCTTC TCTTTATCTC CTTTCTCCTC CTCCACTGTT 
TCTTCAACCA CAACTCTGAG CACAAGCATC TCAGCAAGTA CCACCATGGC CAACAAGCGA 
TCATTCCAGC TCCACCAAGG TGGGAAAAGA AATTTAAAGG TGGCAAAGAA TGGAAGTAAG 
CTTCCTCCAG CCAGCACAAG TAAGAAAGAA GAGCTGGCAT TGTTGGATCA AACAATGCTT 
ACGGAGACAA ATGCCGCAAT AGAAAACCTC AGGGTGGTCA GTGAGACTAA AGAGAGTGTG 
ACATTGACGT GGAATATGAT CAACACCACA CATAACTCTG CAGTGACTGT GTTGTATTCC 
AAGTATGGTG GGAAGGACCT GCTGCTGTTG AATGCAGACT CCAGCAAGAA CCAAGTAACC 
ATAGATGGCT TGGAACCCGG TGGGCAATAC ATGGCCTGTG TCTGTCCAAA AGGAGTGCCT 
CCCCAGAAAG ACCAATGCAT CACCTTTTCT ACTGAAAGAG TTGAAGGAGA TGATTCTCAA 
TGGTCTCTCC TTCTCGTGGT GACCAGTACT GCCTGTGTTG TTATCTTACC ATTGATTTGT 
TTCTTGTTGT ACAAAGTTTG CAAACTGCAA TGTAAATCAG AACCTTTTTG GGAAGATGAT 
TTGGCAAAGG AGACTTATAT CCAATTTGAG ACCCTGTTTC CCAGGTCTCA AAGTGTAGGT 
GAGCTCTGGA CACGAAGCCA CAGGGATGAC TCAGAGAAAT TGCTGCTTTG TTCTAGGTCA 
AGTGTGGAAT CTCAGGTGAC TTTTAAAAGT GAAGGTTCCA GACCAGAGTA TTATTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRIT3 ( NM_198506.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_940908.3 Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), mRNA.

Price & Availability↑

CloneID	OHu21649
Clone ID Related Accession (Same CDS sequence)	NM_198506.5 , NM_198506.4
Accession Version	NM_198506.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2040bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC126283.3, JQ354981.1, DT932743.1, AC005509.1, BC104037.2 and BM665581.1. This sequence is a reference standard in the RefSeqGene project. On May 18, 2013 this sequence version replaced NM_198506.3. Sequence Note: This RefSeq record was created from partial transcripts and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by orthologous alignment from mouse (NP_001192031.1). ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01820689, SAMN01820691 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCATCTCT TTGCATGTCT GTGCATTGTC CTTAGCTTTT TGGAAGGAGT GGGCTGTTTG 
TGTCCTTCAC AGTGCACCTG TGATTATCAC GGCAGAAATG ACGGCTCAGG ATCAAGGTTG 
GTGCTATGTA ATGACATGGA TATGAACGAG CTGCCTACGA ACCTCCCCGT GGACACTGTG 
AAGCTTCGCA TAGAGAAGAC TGTCATCCGC AGAATCTCTG CGGAGGCCTT CTATTACCTG 
GTGGAGCTCC AGTATCTCTG GGTGACTTAC AATTCCGTGG CCAGCATTGA CCCCAGCAGC 
TTTTACAACC TGAAGCAACT GCATGAGTTG CGCTTGGATG GGAATTCTCT GGCTGCTTTC 
CCTTGGGCAT CTCTGCTGGA CATGCCCCTT CTGAGGACCC TGGACTTGCA CAATAACAAA 
ATAACCAGTG TGCCAAATGA GGCGCTCAGG TATCTGAAGA ACCTTGCCTA CTTGGATTTA 
TCAAGCAACA GACTCACCAC ATTGCCACCA GATTTCCTGG AGAGCTGGAC TCATTTAGTT 
TCAACACCTT CTGGAGTCCT GGACCTTTCC CCAAGCAGGA TTATTCTTGG TCTACAGGAC 
AATCCTTGGT TCTGTGACTG TCATATTTCC AAAATGATTG AGTTGTCAAA GGTCGTTGAC 
CCTGCTATAG TGCTTCTGGA TCCACTGATG ACTTGCAGTG AACCTGAGCG CCTCACAGGA 
ATTTTGTTTC AGCGGGCTGA ATTGGAGCAT TGTCTGAAAC CATCAGTGAT GACCTCAGCC 
ACCAAAATCA TGTCTGCTCT GGGCAGTAAT GTTCTACTGC GGTGTGATGC CACTGGCTTC 
CCCACCCCAC AGATCACATG GACCAGATCT GACAGCTCGC CAGTTAATTA TACAGTAATA 
CAAGAATCTC CAGAGGAAGG AGTCAGATGG TCCATAATGA GCTTGACAGG CATTTCTTCC 
AAAGACGCTG GGGATTACAA ATGTAAGGCC AAAAATCTGG CTGGGATGTC AGAAGCTGTG 
GTTACTGTGA CAGTGCTTGG CATTACCACA ACTCCAATAC CACCAGACAC TTCTGAAAGA 
ACTGGAGATC ATCCTGAGTG GGATGTCCAG CCGGGATCTG GAAGATCTAC ATCTGTATCT 
AGCGCATCAT CATATCTTTG GTCCTCTTCC TTCTCCCCCA CATCTTCTTT TTCTGCTTCT 
ACTTTGTCTC CTCCCTCTAC TGCTTCCTTC TCTTTATCTC CTTTCTCCTC CTCCACTGTT 
TCTTCAACCA CAACTCTGAG CACAAGCATC TCAGCAAGTA CCACCATGGC CAACAAGCGA 
TCATTCCAGC TCCACCAAGG TGGGAAAAGA AATTTAAAGG TGGCAAAGAA TGGAAGTAAG 
CTTCCTCCAG CCAGCACAAG TAAGAAAGAA GAGCTGGCAT TGTTGGATCA AACAATGCTT 
ACGGAGACAA ATGCCGCAAT AGAAAACCTC AGGGTGGTCA GTGAGACTAA AGAGAGTGTG 
ACATTGACGT GGAATATGAT CAACACCACA CATAACTCTG CAGTGACTGT GTTGTATTCC 
AAGTATGGTG GGAAGGACCT GCTGCTGTTG AATGCAGACT CCAGCAAGAA CCAAGTAACC 
ATAGATGGCT TGGAACCCGG TGGGCAATAC ATGGCCTGTG TCTGTCCAAA AGGAGTGCCT 
CCCCAGAAAG ACCAATGCAT CACCTTTTCT ACTGAAAGAG TTGAAGGAGA TGATTCTCAA 
TGGTCTCTCC TTCTCGTGGT GACCAGTACT GCCTGTGTTG TTATCTTACC ATTGATTTGT 
TTCTTGTTGT ACAAAGTTTG CAAACTGCAA TGTAAATCAG AACCTTTTTG GGAAGATGAT 
TTGGCAAAGG AGACTTATAT CCAATTTGAG ACCCTGTTTC CCAGGTCTCA AAGTGTAGGT 
GAGCTCTGGA CACGAAGCCA CAGGGATGAC TCAGAGAAAT TGCTGCTTTG TTCTAGGTCA 
AGTGTGGAAT CTCAGGTGAC TTTTAAAAGT GAAGGTTCCA GACCAGAGTA TTATTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_940908.3
CDS	19..2058
Translation	MHLFACLCIVLSFLEGVGCLCPSQCTCDYHGRNDGSGSRLVLCNDMDMNELPTNLPVDTVKLRIEKTVIRRISAEAFYYLVELQYLWVTYNSVASIDPSSFYNLKQLHELRLDGNSLAAFPWASLLDMPLLRTLDLHNNKITSVPNEALRYLKNLAYLDLSSNRLTTLPPDFLESWTHLVSTPSGVLDLSPSRIILGLQDNPWFCDCHISKMIELSKVVDPAIVLLDPLMTCSEPERLTGILFQRAELEHCLKPSVMTSATKIMSALGSNVLLRCDATGFPTPQITWTRSDSSPVNYTVIQESPEEGVRWSIMSLTGISSKDAGDYKCKAKNLAGMSEAVVTVTVLGITTTPIPPDTSERTGDHPEWDVQPGSGRSTSVSSASSYLWSSSFSPTSSFSASTLSPPSTASFSLSPFSSSTVSSTTTLSTSISASTTMANKRSFQLHQGGKRNLKVAKNGSKLPPASTSKKEELALLDQTMLTETNAAIENLRVVSETKESVTLTWNMINTTHNSAVTVLYSKYGGKDLLLLNADSSKNQVTIDGLEPGGQYMACVCPKGVPPQKDQCITFSTERVEGDDSQWSLLLVVTSTACVVILPLICFLLYKVCKLQCKSEPFWEDDLAKETYIQFETLFPRSQSVGELWTRSHRDDSEKLLLCSRSSVESQVTFKSEGSRPEYYC

Target ORF information:

RefSeq Version	NM_198506.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198506.4

ORF Insert Sequence:

ATGCATCTCT TTGCATGTCT GTGCATTGTC CTTAGCTTTT TGGAAGGAGT GGGCTGTTTG 
TGTCCTTCAC AGTGCACCTG TGATTATCAC GGCAGAAATG ACGGCTCAGG ATCAAGGTTG 
GTGCTATGTA ATGACATGGA TATGAACGAG CTGCCTACGA ACCTCCCCGT GGACACTGTG 
AAGCTTCGCA TAGAGAAGAC TGTCATCCGC AGAATCTCTG CGGAGGCCTT CTATTACCTG 
GTGGAGCTCC AGTATCTCTG GGTGACTTAC AATTCCGTGG CCAGCATTGA CCCCAGCAGC 
TTTTACAACC TGAAGCAACT GCATGAGTTG CGCTTGGATG GGAATTCTCT GGCTGCTTTC 
CCTTGGGCAT CTCTGCTGGA CATGCCCCTT CTGAGGACCC TGGACTTGCA CAATAACAAA 
ATAACCAGTG TGCCAAATGA GGCGCTCAGG TATCTGAAGA ACCTTGCCTA CTTGGATTTA 
TCAAGCAACA GACTCACCAC ATTGCCACCA GATTTCCTGG AGAGCTGGAC TCATTTAGTT 
TCAACACCTT CTGGAGTCCT GGACCTTTCC CCAAGCAGGA TTATTCTTGG TCTACAGGAC 
AATCCTTGGT TCTGTGACTG TCATATTTCC AAAATGATTG AGTTGTCAAA GGTCGTTGAC 
CCTGCTATAG TGCTTCTGGA TCCACTGATG ACTTGCAGTG AACCTGAGCG CCTCACAGGA 
ATTTTGTTTC AGCGGGCTGA ATTGGAGCAT TGTCTGAAAC CATCAGTGAT GACCTCAGCC 
ACCAAAATCA TGTCTGCTCT GGGCAGTAAT GTTCTACTGC GGTGTGATGC CACTGGCTTC 
CCCACCCCAC AGATCACATG GACCAGATCT GACAGCTCGC CAGTTAATTA TACAGTAATA 
CAAGAATCTC CAGAGGAAGG AGTCAGATGG TCCATAATGA GCTTGACAGG CATTTCTTCC 
AAAGACGCTG GGGATTACAA ATGTAAGGCC AAAAATCTGG CTGGGATGTC AGAAGCTGTG 
GTTACTGTGA CAGTGCTTGG CATTACCACA ACTCCAATAC CACCAGACAC TTCTGAAAGA 
ACTGGAGATC ATCCTGAGTG GGATGTCCAG CCGGGATCTG GAAGATCTAC ATCTGTATCT 
AGCGCATCAT CATATCTTTG GTCCTCTTCC TTCTCCCCCA CATCTTCTTT TTCTGCTTCT 
ACTTTGTCTC CTCCCTCTAC TGCTTCCTTC TCTTTATCTC CTTTCTCCTC CTCCACTGTT 
TCTTCAACCA CAACTCTGAG CACAAGCATC TCAGCAAGTA CCACCATGGC CAACAAGCGA 
TCATTCCAGC TCCACCAAGG TGGGAAAAGA AATTTAAAGG TGGCAAAGAA TGGAAGTAAG 
CTTCCTCCAG CCAGCACAAG TAAGAAAGAA GAGCTGGCAT TGTTGGATCA AACAATGCTT 
ACGGAGACAA ATGCCGCAAT AGAAAACCTC AGGGTGGTCA GTGAGACTAA AGAGAGTGTG 
ACATTGACGT GGAATATGAT CAACACCACA CATAACTCTG CAGTGACTGT GTTGTATTCC 
AAGTATGGTG GGAAGGACCT GCTGCTGTTG AATGCAGACT CCAGCAAGAA CCAAGTAACC 
ATAGATGGCT TGGAACCCGG TGGGCAATAC ATGGCCTGTG TCTGTCCAAA AGGAGTGCCT 
CCCCAGAAAG ACCAATGCAT CACCTTTTCT ACTGAAAGAG TTGAAGGAGA TGATTCTCAA 
TGGTCTCTCC TTCTCGTGGT GACCAGTACT GCCTGTGTTG TTATCTTACC ATTGATTTGT 
TTCTTGTTGT ACAAAGTTTG CAAACTGCAA TGTAAATCAG AACCTTTTTG GGAAGATGAT 
TTGGCAAAGG AGACTTATAT CCAATTTGAG ACCCTGTTTC CCAGGTCTCA AAGTGTAGGT 
GAGCTCTGGA CACGAAGCCA CAGGGATGAC TCAGAGAAAT TGCTGCTTTG TTCTAGGTCA 
AGTGTGGAAT CTCAGGTGAC TTTTAAAAGT GAAGGTTCCA GACCAGAGTA TTATTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRIT3 ( XM_017008167.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863656.1 Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu38919
Clone ID Related Accession (Same CDS sequence)	XM_017008167.1
Accession Version	XM_017008167.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTTGAGC CTCATCAGGA ACCCAGGCAC AGTAAAGTTG GTCTACAGGA CAATCCTTGG 
TTCTGTGACT GTCATATTTC CAAAATGATT GAGTTGTCAA AGGTCGTTGA CCCTGCTATA 
GTGCTTCTGG ATCCACTGAT GACTTGCAGT GAACCTGAGC GCCTCACAGG AATTTTGTTT 
CAGCGGGCTG AATTGGAGCA TTGTCTGAAA CCATCAGTGA TGACCTCAGC CACCAAAATC 
ATGTCTGCTC TGGGCAGTAA TGTTCTACTG CGGTGTGATG CCACTGGCTT CCCCACCCCA 
CAGATCACAT GGACCAGATC TGACAGCTCG CCAGTTAATT ATACAGTAAT ACAAGAATCT 
CCAGAGGAAG GAGTCAGATG GTCCATAATG AGCTTGACAG GCATTTCTTC CAAAGACGCT 
GGGGATTACA AATGTAAGGC CAAAAATCTG GCTGGGATGT CAGAAGCTGT GGTTACTGTG 
ACAGTGCTTG GCATTACCAC AACTCCAATA CCACCAGACA CTTCTGAAAG AACTGGAGAT 
CATCCTGAGT GGGATGTCCA GCCGGGATCT GGAAGATCTA CATCTGTATC TAGCGCATCA 
TCATATCTTT GGTCCTCTTC CTTCTCCCCC ACATCTTCTT TTTCTGCTTC TACTTTGTCT 
CCTCCCTCTA CTGCTTCCTT CTCTTTATCT CCTTTCTCCT CCTCCACTGT TTCTTCAACC 
ACAACTCTGA GCACAAGCAT CTCAGCAAGT ACCACCATGG CCAACAAGCG ATCATTCCAG 
CTCCACCAAG GTGGGAAAAG AAATTTAAAG GTGGCAAAGA ATGGAAGTAA GCTTCCTCCA 
GCCAGCACAA GTAAGAAAGA AGAGCTGGCA TTGTTGGATC AAACAATGCT TACGGAGACA 
AATGCCGCAA TAGAAAACCT CAGGGTGGTC AGTGAGACTA AAGAGAGTGT GACATTGACG 
TGGAATATGA TCAACACCAC ACATAACTCT GCAGTGACTG TGTTGTATTC CAAGTATGGT 
GGGAAGGACC TGCTGCTGTT GAATGCAGAC TCCAGCAAGA ACCAAGTAAC CATAGATGGC 
TTGGAACCCG GTGGGCAATA CATGGCCTGT GTCTGTCCAA AAGGAGTGCC TCCCCAGAAA 
GACCAATGCA TCACCTTTTC TACTGAAAGA GTTGAAGGAG ATGATTCTCA ATGGTCTCTC 
CTTCTCGTGG TGACCAGTAC TGCCTGTGTT GTTATCTTAC CATTGATTTG TTTCTTGTTG 
TACAAAGTTT GCAAACTGCA ATGTAAATCA GAACCTTTTT GGGAAGATGA TTTGGCAAAG 
GAGACTTATA TCCAATTTGA GACCCTGTTT CCCAGGTCTC AAAGTGTAGG TGAGCTCTGG 
ACACGAAGCC ACAGGGATGA CTCAGAGAAA TTGCTGCTTT GTTCTAGGTC AAGTGTGGAA 
TCTCAGGTGA CTTTTAAAAG TGAAGGTTCC AGACCAGAGT ATTATTGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863656.1
CDS	190..1680
Translation	MVEPHQEPRHSKVGLQDNPWFCDCHISKMIELSKVVDPAIVLLDPLMTCSEPERLTGILFQRAELEHCLKPSVMTSATKIMSALGSNVLLRCDATGFPTPQITWTRSDSSPVNYTVIQESPEEGVRWSIMSLTGISSKDAGDYKCKAKNLAGMSEAVVTVTVLGITTTPIPPDTSERTGDHPEWDVQPGSGRSTSVSSASSYLWSSSFSPTSSFSASTLSPPSTASFSLSPFSSSTVSSTTTLSTSISASTTMANKRSFQLHQGGKRNLKVAKNGSKLPPASTSKKEELALLDQTMLTETNAAIENLRVVSETKESVTLTWNMINTTHNSAVTVLYSKYGGKDLLLLNADSSKNQVTIDGLEPGGQYMACVCPKGVPPQKDQCITFSTERVEGDDSQWSLLLVVTSTACVVILPLICFLLYKVCKLQCKSEPFWEDDLAKETYIQFETLFPRSQSVGELWTRSHRDDSEKLLLCSRSSVESQVTFKSEGSRPEYYC

Target ORF information:

RefSeq Version	XM_017008167.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008167.1

ORF Insert Sequence:

ATGGTTGAGC CTCATCAGGA ACCCAGGCAC AGTAAAGTTG GTCTACAGGA CAATCCTTGG 
TTCTGTGACT GTCATATTTC CAAAATGATT GAGTTGTCAA AGGTCGTTGA CCCTGCTATA 
GTGCTTCTGG ATCCACTGAT GACTTGCAGT GAACCTGAGC GCCTCACAGG AATTTTGTTT 
CAGCGGGCTG AATTGGAGCA TTGTCTGAAA CCATCAGTGA TGACCTCAGC CACCAAAATC 
ATGTCTGCTC TGGGCAGTAA TGTTCTACTG CGGTGTGATG CCACTGGCTT CCCCACCCCA 
CAGATCACAT GGACCAGATC TGACAGCTCG CCAGTTAATT ATACAGTAAT ACAAGAATCT 
CCAGAGGAAG GAGTCAGATG GTCCATAATG AGCTTGACAG GCATTTCTTC CAAAGACGCT 
GGGGATTACA AATGTAAGGC CAAAAATCTG GCTGGGATGT CAGAAGCTGT GGTTACTGTG 
ACAGTGCTTG GCATTACCAC AACTCCAATA CCACCAGACA CTTCTGAAAG AACTGGAGAT 
CATCCTGAGT GGGATGTCCA GCCGGGATCT GGAAGATCTA CATCTGTATC TAGCGCATCA 
TCATATCTTT GGTCCTCTTC CTTCTCCCCC ACATCTTCTT TTTCTGCTTC TACTTTGTCT 
CCTCCCTCTA CTGCTTCCTT CTCTTTATCT CCTTTCTCCT CCTCCACTGT TTCTTCAACC 
ACAACTCTGA GCACAAGCAT CTCAGCAAGT ACCACCATGG CCAACAAGCG ATCATTCCAG 
CTCCACCAAG GTGGGAAAAG AAATTTAAAG GTGGCAAAGA ATGGAAGTAA GCTTCCTCCA 
GCCAGCACAA GTAAGAAAGA AGAGCTGGCA TTGTTGGATC AAACAATGCT TACGGAGACA 
AATGCCGCAA TAGAAAACCT CAGGGTGGTC AGTGAGACTA AAGAGAGTGT GACATTGACG 
TGGAATATGA TCAACACCAC ACATAACTCT GCAGTGACTG TGTTGTATTC CAAGTATGGT 
GGGAAGGACC TGCTGCTGTT GAATGCAGAC TCCAGCAAGA ACCAAGTAAC CATAGATGGC 
TTGGAACCCG GTGGGCAATA CATGGCCTGT GTCTGTCCAA AAGGAGTGCC TCCCCAGAAA 
GACCAATGCA TCACCTTTTC TACTGAAAGA GTTGAAGGAG ATGATTCTCA ATGGTCTCTC 
CTTCTCGTGG TGACCAGTAC TGCCTGTGTT GTTATCTTAC CATTGATTTG TTTCTTGTTG 
TACAAAGTTT GCAAACTGCA ATGTAAATCA GAACCTTTTT GGGAAGATGA TTTGGCAAAG 
GAGACTTATA TCCAATTTGA GACCCTGTTT CCCAGGTCTC AAAGTGTAGG TGAGCTCTGG 
ACACGAAGCC ACAGGGATGA CTCAGAGAAA TTGCTGCTTT GTTCTAGGTC AAGTGTGGAA 
TCTCAGGTGA CTTTTAAAAG TGAAGGTTCC AGACCAGAGT ATTATTGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRIT3 ( XM_017008168.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863657.1 Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu95162
Clone ID Related Accession (Same CDS sequence)	XM_017008168.1
Accession Version	XM_017008168.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 594bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATCTCT TTGCATGTCT GTGCATTGTC CTTAGCTTTT TGGAAGGAGT GGGCTGTTTG 
TGTCCTTCAC AGTGCACCTG TGATTATCAC GGCAGAAATG ACGGCTCAGG ATCAAGGTTG 
GTGCTATGTA ATGACATGGA TATGAACGAG CTGCCTACGA ACCTCCCCGT GGACACTGTG 
AAGCTTCGCA TAGAGAAGAC TGTCATCCGC AGAATCTCTG CGGAGGCCTT CTATTACCTG 
GTGGAGCTCC AGTATCTCTG GGTGACTTAC AATTCCGTGG CCAGCATTGA CCCCAGCAGC 
TTTTACAACC TGAAGCAACT GCATGAGTTG CGCTTGGATG GGAATTCTCT GGCTGCTTTC 
CCTTGGGCAT CTCTGCTGGA CATGCCCCTT CTGAGGACCC TGGACTTGCA CAATAACAAA 
ATAACCAGTG TGCCAAATGA GGCGCTCAGG TATCTGAAGA ACCTTGCCTA CTTGGATTTA 
TCAAGCAACA GACTCACCAC ATTGCCACCA GATTTCCTGG AGAGCTGGAC TCATTTAGTT 
TCAACACCTT CTGGAGTCCT GGACCTTTCC CCAAGCAGGA TTATTCTTGG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863657.1
CDS	21..614
Translation	MHLFACLCIVLSFLEGVGCLCPSQCTCDYHGRNDGSGSRLVLCNDMDMNELPTNLPVDTVKLRIEKTVIRRISAEAFYYLVELQYLWVTYNSVASIDPSSFYNLKQLHELRLDGNSLAAFPWASLLDMPLLRTLDLHNNKITSVPNEALRYLKNLAYLDLSSNRLTTLPPDFLESWTHLVSTPSGVLDLSPSRIILG

Target ORF information:

RefSeq Version	XM_017008168.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat, Ig-like and transmembrane domains 3 (LRIT3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008168.1

ORF Insert Sequence:

ATGCATCTCT TTGCATGTCT GTGCATTGTC CTTAGCTTTT TGGAAGGAGT GGGCTGTTTG 
TGTCCTTCAC AGTGCACCTG TGATTATCAC GGCAGAAATG ACGGCTCAGG ATCAAGGTTG 
GTGCTATGTA ATGACATGGA TATGAACGAG CTGCCTACGA ACCTCCCCGT GGACACTGTG 
AAGCTTCGCA TAGAGAAGAC TGTCATCCGC AGAATCTCTG CGGAGGCCTT CTATTACCTG 
GTGGAGCTCC AGTATCTCTG GGTGACTTAC AATTCCGTGG CCAGCATTGA CCCCAGCAGC 
TTTTACAACC TGAAGCAACT GCATGAGTTG CGCTTGGATG GGAATTCTCT GGCTGCTTTC 
CCTTGGGCAT CTCTGCTGGA CATGCCCCTT CTGAGGACCC TGGACTTGCA CAATAACAAA 
ATAACCAGTG TGCCAAATGA GGCGCTCAGG TATCTGAAGA ACCTTGCCTA CTTGGATTTA 
TCAAGCAACA GACTCACCAC ATTGCCACCA GATTTCCTGG AGAGCTGGAC TCATTTAGTT 
TCAACACCTT CTGGAGTCCT GGACCTTTCC CCAAGCAGGA TTATTCTTGG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutation screening of the LRIT3, CABP4, and GPR179 genes in Chinese patients with Schubert-Bornschein congenital stationary night blindness.
Ophthalmic genetics38(3)206-210(2017 May-Jun)
Dan H,Song X,Li J,Xing Y,Li T

LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells.
Investigative ophthalmology & visual science58(3)1768-1778(2017 03)
Neuill? M,Cao Y,Caplette R,Guerrero-Given D,Thomas C,Kamasawa N,Sahel JA,Hamel CP,Audo I,Picaud S,Martemyanov KA,Zeitz C

Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness.
American journal of human genetics92(1)67-75(2013 Jan)
Zeitz C,Jacobson SG,Hamel CP,Bujakowska K,Neuill? M,Orhan E,Zanlonghi X,Lancelot ME,Michiels C,Schwartz SB,Bocquet B,,Antonio A,Audier C,Letexier M,Saraiva JP,Luu TD,Sennlaub F,Nguyen H,Poch O,Dollfus H,Lecompte O,Kohl S,Sahel JA,Bhattacharya SS,Audo I

Leucine-rich repeat, immunoglobulin-like and transmembrane domain 3 (LRIT3) is a modulator of FGFR1.
FEBS letters586(10)1516-21(2012 May)
Kim SD,Liu JL,Roscioli T,Buckley MF,Yagnik G,Boyadjiev SA,Kim J

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Human molecular genetics19(12)2497-506(2010 Jun)
Kalsi G,Kuo PH,Aliev F,Alexander J,McMichael O,Patterson DG,Walsh D,Zhao Z,Schuckit M,Nurnberger J Jr,Edenberg H,Kramer J,Hesselbrock V,Tischfield JA,Vladimirov V,Prescott CA,Dick DM,Kendler KS,Riley BP

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LRIT3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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