IFIT2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IFIT2
Entrez Gene ID	3433
Full Name	interferon induced protein with tetratricopeptide repeats 2
Synonyms	G10P2,GARG-39,IFI-54,IFI-54K,IFI54,IFIT-2,ISG-54 K,ISG-54K,ISG54,P54,cig42
General protein information	Preferred Names interferon induced protein with tetratricopeptide repeats 2 Names interferon-induced protein with tetratricopeptide repeats 2 Interferon, alpha-inducible protein (MW 54kD) interferon-induced 54 kDa protein interferon-induced protein 54
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q23.31
Disorder MIM:	147040

mRNA and Protein(s)

mRNA	Protein	Name
NM_001547.4	NP_001538.4	interferon-induced protein with tetratricopeptide repeats 2
NM_001547.5	NP_001538.4	interferon-induced protein with tetratricopeptide repeats 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	IFIT2	XP_507902.2
	IFIT2	XP_001086302.1
Canis lupus familiaris (dog)	IFIT2	XP_005618815.1
Bos taurus (cattle)	IFIT2	XP_002698402.1
Rattus norvegicus (Norway rat)	Ifit2	NP_001019924.1
Mus musculus (house mouse)	Ifit2	NP_032358.1
Homo sapiens (human)	IFIT2	NP_001538.4

Gene Ontology
Bibliography

Related articles in PubMed

PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Shen H, Zhan M, Zhang Y, Huang S, Xu S, Huang X, He M, Yao Y, Man M, Wang J
Cell death & disease9(2)71(2018 Jan)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Inhibition of Proteasome Activity Induces Aggregation of IFIT2 in the Centrosome and Enhances IFIT2-Induced Cell Apoptosis.
Chen L, Liu S, Xu F, Kong Y, Wan L, Zhang Y, Zhang Z
International journal of biological sciences13(3)383-390(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mechanistic investigations reveal that AJUBA specifically binds the FERM domain of JAK1 to dissociate JAK1 from the IFNgamma recepter, resulting in an inhibition of STAT1 phosporylation and concomitantly its nuclear translocation. Clinically, the level of AJUBA in CRC specimens is negatively correlated with the levels of IFIT2 and pSTAT1
Title: The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network.

The results of the present study revealed that the inhibition of proteasome activity blocked the degradation of IFIT2 and promoted the aggregation of IFIT2 in the centrosome, which in turn induced cell apoptosis. In short, IFIT2 may be a potential target for cancer therapeutics.
Title: Inhibition of Proteasome Activity Induces Aggregation of IFIT2 in the Centrosome and Enhances IFIT2-Induced Cell Apoptosis.

LINC00161 is an essential regulator in cisplatin-induced apoptosis, and the LINC00161-miR-645-IFIT2 signalling axis plays an important role in reducing osteosarcoma chemoresistance.
Title: Long non-coding RNA LINC00161 sensitises osteosarcoma cells to cisplatin-induced apoptosis by regulating the miR-645-IFIT2 axis.

there is a positive feedback loop between phosphorylated STAT1 and ISG56, ISG54 or ISG60.
Title: Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-?/STAT1 axis in U373MG human astrocytoma cells.

Data shows that IFIT2 expression is downregulated in adenocarcinoma of gastric esophageal junction cells; its ectopic expression leads to cell apoptosis, suggesting its role as a tumor suppressor.
Title: MicroRNA-645, up-regulated in human adencarcinoma of gastric esophageal junction, inhibits apoptosis by targeting tumor suppressor IFIT2.

The following IFIT2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IFIT2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31069	NM_001547.5 Latest version!	Homo sapiens interferon induced protein with tetratricopeptide repeats 2 (IFIT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu31069	NM_001547.4	Homo sapiens interferon induced protein with tetratricopeptide repeats 2 (IFIT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IFIT2 ( NM_001547.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001538.4 Homo sapiens interferon induced protein with tetratricopeptide repeats 2 (IFIT2), mRNA.

Price & Availability↑

CloneID	OHu31069
Clone ID Related Accession (Same CDS sequence)	NM_001547.4 , NM_001547.5
Accession Version	NM_001547.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1419bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-12
Organism	Homo sapiens(human)
Product	interferon-induced protein with tetratricopeptide repeats 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA631671.1, BC005987.1, EB387611.1, AA143609.1, AL353751.13 and AA765174.1. On Jul 24, 2007 this sequence version replaced NM_001547.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.208246.1, SRR1660805.60084.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTGAGA ACAATAAGAA TTCCTTGGAG AGCAGCCTAC GGCAACTAAA ATGCCATTTC 
ACCTGGAACT TGATGGAGGG AGAAAACTCC TTGGATGATT TTGAAGACAA AGTATTTTAC 
CGGACTGAGT TTCAGAATCG TGAATTCAAA GCCACAATGT GCAACCTACT GGCCTATCTA 
AAGCACCTCA AAGGGCAAAA CGAGGCAGCC CTGGAATGCT TACGTAAAGC TGAAGAGTTA 
ATCCAGCAAG AGCATGCTGA CCAGGCAGAA ATCAGAAGTC TGGTCACCTG GGGAAACTAT 
GCCTGGGTCT ACTATCACAT GGGCCGACTC TCAGACGTTC AGATTTATGT AGACAAGGTG 
AAACATGTCT GTGAGAAGTT TTCCAGTCCC TATAGAATTG AGAGTCCAGA GCTTGACTGT 
GAGGAAGGGT GGACACGGTT AAAGTGTGGA GGAAACCAAA ATGAAAGAGC GAAGGTGTGC 
TTTGAGAAGG CTCTGGAAAA GAAGCCAAAG AACCCAGAAT TCACCTCTGG ACTGGCAATA 
GCAAGCTACC GTCTGGACAA CTGGCCACCA TCTCAGAACG CCATTGACCC TCTGAGGCAA 
GCCATTCGGC TGAATCCTGA CAACCAGTAC CTTAAAGTCC TCCTGGCTCT GAAGCTTCAT 
AAGATGCGTG AAGAAGGTGA AGAGGAAGGT GAAGGAGAGA AGTTAGTTGA AGAAGCCTTG 
GAGAAAGCCC CAGGTGTAAC AGATGTTCTT CGCAGTGCAG CCAAGTTTTA TCGAAGAAAA 
GATGAGCCAG ACAAAGCGAT TGAACTGCTT AAAAAGGCTT TAGAATACAT ACCAAACAAT 
GCCTACCTGC ATTGCCAAAT TGGGTGCTGC TATAGGGCAA AAGTCTTCCA AGTAATGAAT 
CTAAGAGAGA ATGGAATGTA TGGGAAAAGA AAGTTACTGG AACTAATAGG ACACGCTGTG 
GCTCATCTGA AGAAAGCTGA TGAGGCCAAT GATAATCTCT TCCGTGTCTG TTCCATTCTT 
GCCAGCCTCC ATGCTCTAGC AGATCAGTAT GAAGACGCAG AGTATTACTT CCAAAAGGAA 
TTCAGTAAAG AGCTTACTCC TGTAGCGAAA CAACTGCTCC ATCTGCGGTA TGGCAACTTT 
CAGCTGTACC AAATGAAGTG TGAAGACAAG GCCATCCACC ACTTTATAGA GGGTGTAAAA 
ATAAACCAGA AATCAAGGGA GAAAGAAAAG ATGAAAGACA AACTGCAAAA AATTGCCAAA 
ATGCGACTTT CTAAAAATGG AGCAGATTCT GAGGCTTTGC ATGTCTTGGC ATTCCTTCAG 
GAGCTGAATG AAAAAATGCA ACAAGCAGAT GAAGACTCTG AGAGGGGTTT GGAGTCTGGA 
AGCCTCATCC CTTCAGCATC AAGCTGGAAT GGGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001538.4
CDS	176..1594
Translation	MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE

Target ORF information:

RefSeq Version	NM_001547.4
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon induced protein with tetratricopeptide repeats 2 (IFIT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001547.4

ORF Insert Sequence:

ATGAGTGAGA ACAATAAGAA TTCCTTGGAG AGCAGCCTAC GGCAACTAAA ATGCCATTTC 
ACCTGGAACT TGATGGAGGG AGAAAACTCC TTGGATGATT TTGAAGACAA AGTATTTTAC 
CGGACTGAGT TTCAGAATCG TGAATTCAAA GCCACAATGT GCAACCTACT GGCCTATCTA 
AAGCACCTCA AAGGGCAAAA CGAGGCAGCC CTGGAATGCT TACGTAAAGC TGAAGAGTTA 
ATCCAGCAAG AGCATGCTGA CCAGGCAGAA ATCAGAAGTC TGGTCACCTG GGGAAACTAT 
GCCTGGGTCT ACTATCACAT GGGCCGACTC TCAGACGTTC AGATTTATGT AGACAAGGTG 
AAACATGTCT GTGAGAAGTT TTCCAGTCCC TATAGAATTG AGAGTCCAGA GCTTGACTGT 
GAGGAAGGGT GGACACGGTT AAAGTGTGGA GGAAACCAAA ATGAAAGAGC GAAGGTGTGC 
TTTGAGAAGG CTCTGGAAAA GAAGCCAAAG AACCCAGAAT TCACCTCTGG ACTGGCAATA 
GCAAGCTACC GTCTGGACAA CTGGCCACCA TCTCAGAACG CCATTGACCC TCTGAGGCAA 
GCCATTCGGC TGAATCCTGA CAACCAGTAC CTTAAAGTCC TCCTGGCTCT GAAGCTTCAT 
AAGATGCGTG AAGAAGGTGA AGAGGAAGGT GAAGGAGAGA AGTTAGTTGA AGAAGCCTTG 
GAGAAAGCCC CAGGTGTAAC AGATGTTCTT CGCAGTGCAG CCAAGTTTTA TCGAAGAAAA 
GATGAGCCAG ACAAAGCGAT TGAACTGCTT AAAAAGGCTT TAGAATACAT ACCAAACAAT 
GCCTACCTGC ATTGCCAAAT TGGGTGCTGC TATAGGGCAA AAGTCTTCCA AGTAATGAAT 
CTAAGAGAGA ATGGAATGTA TGGGAAAAGA AAGTTACTGG AACTAATAGG ACACGCTGTG 
GCTCATCTGA AGAAAGCTGA TGAGGCCAAT GATAATCTCT TCCGTGTCTG TTCCATTCTT 
GCCAGCCTCC ATGCTCTAGC AGATCAGTAT GAAGACGCAG AGTATTACTT CCAAAAGGAA 
TTCAGTAAAG AGCTTACTCC TGTAGCGAAA CAACTGCTCC ATCTGCGGTA TGGCAACTTT 
CAGCTGTACC AAATGAAGTG TGAAGACAAG GCCATCCACC ACTTTATAGA GGGTGTAAAA 
ATAAACCAGA AATCAAGGGA GAAAGAAAAG ATGAAAGACA AACTGCAAAA AATTGCCAAA 
ATGCGACTTT CTAAAAATGG AGCAGATTCT GAGGCTTTGC ATGTCTTGGC ATTCCTTCAG 
GAGCTGAATG AAAAAATGCA ACAAGCAGAT GAAGACTCTG AGAGGGGTTT GGAGTCTGGA 
AGCCTCATCC CTTCAGCATC AAGCTGGAAT GGGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IFIT2 ( NM_001547.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001538.4 Homo sapiens interferon induced protein with tetratricopeptide repeats 2 (IFIT2), mRNA.

Price & Availability↑

CloneID	OHu31069
Clone ID Related Accession (Same CDS sequence)	NM_001547.4 , NM_001547.5
Accession Version	NM_001547.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1419bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	interferon-induced protein with tetratricopeptide repeats 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC005987.1, EB387611.1, AA143609.1, AL353751.13 and AA765174.1. On Nov 22, 2018 this sequence version replaced NM_001547.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.111580.1, SRR1803611.208246.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371826.4/ ENSP00000360891.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGTGAGA ACAATAAGAA TTCCTTGGAG AGCAGCCTAC GGCAACTAAA ATGCCATTTC 
ACCTGGAACT TGATGGAGGG AGAAAACTCC TTGGATGATT TTGAAGACAA AGTATTTTAC 
CGGACTGAGT TTCAGAATCG TGAATTCAAA GCCACAATGT GCAACCTACT GGCCTATCTA 
AAGCACCTCA AAGGGCAAAA CGAGGCAGCC CTGGAATGCT TACGTAAAGC TGAAGAGTTA 
ATCCAGCAAG AGCATGCTGA CCAGGCAGAA ATCAGAAGTC TGGTCACCTG GGGAAACTAT 
GCCTGGGTCT ACTATCACAT GGGCCGACTC TCAGACGTTC AGATTTATGT AGACAAGGTG 
AAACATGTCT GTGAGAAGTT TTCCAGTCCC TATAGAATTG AGAGTCCAGA GCTTGACTGT 
GAGGAAGGGT GGACACGGTT AAAGTGTGGA GGAAACCAAA ATGAAAGAGC GAAGGTGTGC 
TTTGAGAAGG CTCTGGAAAA GAAGCCAAAG AACCCAGAAT TCACCTCTGG ACTGGCAATA 
GCAAGCTACC GTCTGGACAA CTGGCCACCA TCTCAGAACG CCATTGACCC TCTGAGGCAA 
GCCATTCGGC TGAATCCTGA CAACCAGTAC CTTAAAGTCC TCCTGGCTCT GAAGCTTCAT 
AAGATGCGTG AAGAAGGTGA AGAGGAAGGT GAAGGAGAGA AGTTAGTTGA AGAAGCCTTG 
GAGAAAGCCC CAGGTGTAAC AGATGTTCTT CGCAGTGCAG CCAAGTTTTA TCGAAGAAAA 
GATGAGCCAG ACAAAGCGAT TGAACTGCTT AAAAAGGCTT TAGAATACAT ACCAAACAAT 
GCCTACCTGC ATTGCCAAAT TGGGTGCTGC TATAGGGCAA AAGTCTTCCA AGTAATGAAT 
CTAAGAGAGA ATGGAATGTA TGGGAAAAGA AAGTTACTGG AACTAATAGG ACACGCTGTG 
GCTCATCTGA AGAAAGCTGA TGAGGCCAAT GATAATCTCT TCCGTGTCTG TTCCATTCTT 
GCCAGCCTCC ATGCTCTAGC AGATCAGTAT GAAGACGCAG AGTATTACTT CCAAAAGGAA 
TTCAGTAAAG AGCTTACTCC TGTAGCGAAA CAACTGCTCC ATCTGCGGTA TGGCAACTTT 
CAGCTGTACC AAATGAAGTG TGAAGACAAG GCCATCCACC ACTTTATAGA GGGTGTAAAA 
ATAAACCAGA AATCAAGGGA GAAAGAAAAG ATGAAAGACA AACTGCAAAA AATTGCCAAA 
ATGCGACTTT CTAAAAATGG AGCAGATTCT GAGGCTTTGC ATGTCTTGGC ATTCCTTCAG 
GAGCTGAATG AAAAAATGCA ACAAGCAGAT GAAGACTCTG AGAGGGGTTT GGAGTCTGGA 
AGCCTCATCC CTTCAGCATC AAGCTGGAAT GGGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001538.4
CDS	79..1497
Translation	MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE

Target ORF information:

RefSeq Version	NM_001547.5
Organism	Homo sapiens(human)
Definition	Homo sapiens interferon induced protein with tetratricopeptide repeats 2 (IFIT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001547.5

ORF Insert Sequence:

ATGAGTGAGA ACAATAAGAA TTCCTTGGAG AGCAGCCTAC GGCAACTAAA ATGCCATTTC 
ACCTGGAACT TGATGGAGGG AGAAAACTCC TTGGATGATT TTGAAGACAA AGTATTTTAC 
CGGACTGAGT TTCAGAATCG TGAATTCAAA GCCACAATGT GCAACCTACT GGCCTATCTA 
AAGCACCTCA AAGGGCAAAA CGAGGCAGCC CTGGAATGCT TACGTAAAGC TGAAGAGTTA 
ATCCAGCAAG AGCATGCTGA CCAGGCAGAA ATCAGAAGTC TGGTCACCTG GGGAAACTAT 
GCCTGGGTCT ACTATCACAT GGGCCGACTC TCAGACGTTC AGATTTATGT AGACAAGGTG 
AAACATGTCT GTGAGAAGTT TTCCAGTCCC TATAGAATTG AGAGTCCAGA GCTTGACTGT 
GAGGAAGGGT GGACACGGTT AAAGTGTGGA GGAAACCAAA ATGAAAGAGC GAAGGTGTGC 
TTTGAGAAGG CTCTGGAAAA GAAGCCAAAG AACCCAGAAT TCACCTCTGG ACTGGCAATA 
GCAAGCTACC GTCTGGACAA CTGGCCACCA TCTCAGAACG CCATTGACCC TCTGAGGCAA 
GCCATTCGGC TGAATCCTGA CAACCAGTAC CTTAAAGTCC TCCTGGCTCT GAAGCTTCAT 
AAGATGCGTG AAGAAGGTGA AGAGGAAGGT GAAGGAGAGA AGTTAGTTGA AGAAGCCTTG 
GAGAAAGCCC CAGGTGTAAC AGATGTTCTT CGCAGTGCAG CCAAGTTTTA TCGAAGAAAA 
GATGAGCCAG ACAAAGCGAT TGAACTGCTT AAAAAGGCTT TAGAATACAT ACCAAACAAT 
GCCTACCTGC ATTGCCAAAT TGGGTGCTGC TATAGGGCAA AAGTCTTCCA AGTAATGAAT 
CTAAGAGAGA ATGGAATGTA TGGGAAAAGA AAGTTACTGG AACTAATAGG ACACGCTGTG 
GCTCATCTGA AGAAAGCTGA TGAGGCCAAT GATAATCTCT TCCGTGTCTG TTCCATTCTT 
GCCAGCCTCC ATGCTCTAGC AGATCAGTAT GAAGACGCAG AGTATTACTT CCAAAAGGAA 
TTCAGTAAAG AGCTTACTCC TGTAGCGAAA CAACTGCTCC ATCTGCGGTA TGGCAACTTT 
CAGCTGTACC AAATGAAGTG TGAAGACAAG GCCATCCACC ACTTTATAGA GGGTGTAAAA 
ATAAACCAGA AATCAAGGGA GAAAGAAAAG ATGAAAGACA AACTGCAAAA AATTGCCAAA 
ATGCGACTTT CTAAAAATGG AGCAGATTCT GAGGCTTTGC ATGTCTTGGC ATTCCTTCAG 
GAGCTGAATG AAAAAATGCA ACAAGCAGAT GAAGACTCTG AGAGGGGTTT GGAGTCTGGA 
AGCCTCATCC CTTCAGCATC AAGCTGGAAT GGGGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Cell death & disease9(2)71(2018 Jan)
Shen H,Zhan M,Zhang Y,Huang S,Xu S,Huang X,He M,Yao Y,Man M,Wang J

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Inhibition of Proteasome Activity Induces Aggregation of IFIT2 in the Centrosome and Enhances IFIT2-Induced Cell Apoptosis.
International journal of biological sciences13(3)383-390(2017)
Chen L,Liu S,Xu F,Kong Y,Wan L,Zhang Y,Zhang Z

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IFIT2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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