GOLGA6A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GOLGA6A
Entrez Gene ID	342096
Full Name	golgin A6 family member A
Synonyms	GLP,GOLGA6
General protein information	Preferred Names golgin A6 family member A Names golgin subfamily A member 6A Golgin linked to PML golgi autoantigen, golgin subfamily a, 6 golgi autoantigen, golgin subfamily a, 6A golgi autoantigen, golgin subfamily a, member 6 golgin-like protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q24.1
Summary	The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The protein encoded by this gene is a member of the golgin family of proteins, whose members localize to the Golgi. This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, that are greather than 90% similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosome rearrangements that underlie genomic disease. The protein encoded by this gene is thought to be a functional golgin protein while the majority of the related copies of this gene are thought to be transcribed pseudogenes. [provided by RefSeq, Jul 2008].
Disorder MIM:	610288

mRNA and Protein(s)

mRNA	Protein	Name
NM_001038640.2	NP_001033729.2	golgin subfamily A member 6A

Pathways from BioSystems

Homologies

	LOC713596	XP_001103006.2
Homo sapiens (human)	GOLGA6A	NP_001033729.2
Homo sapiens (human)	GOLGA6C	NP_001157876.1
Homo sapiens (human)	GOLGA6B	NP_061122.4
Homo sapiens (human)	GOLGA6D	NP_001138696.1

Gene Ontology
Bibliography

Related articles in PubMed

Neocentromeres in 15q24-26 map to duplicons which flanked an ancestral centromere in 15q25.
Ventura M, Mudge JM, Palumbo V, Burn S, Blennow E, Pierluigi M, Giorda R, Zuffardi O, Archidiacono N, Jackson MS, Rocchi M
Genome research13(9)2059-68(2003 Sep)

Human chromosome 15q11-q14 regions of rearrangements contain clusters of LCR15 duplicons.
Pujana MA, Nadal M, Guitart M, Armengol L, Gratac?s M, Estivill X
European journal of human genetics : EJHG10(1)26-35(2002 Jan)

A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders.
Gratac?s M, Nadal M, Mart?n-Santos R, Pujana MA, Gago J, Peral B, Armengol L, Ponsa I, Mir? R, Bulbena A, Estivill X
Cell106(3)367-79(2001 Aug)

Additional complexity on human chromosome 15q: identification of a set of newly recognized duplicons (LCR15) on 15q11-q13, 15q24, and 15q26.
Pujana MA, Nadal M, Gratac?s M, Peral B, Csiszar K, Gonz?lez-Sarmiento R, Sumoy L, Estivill X
Genome research11(1)98-111(2001 Jan)

Cloning and characterization of a Golgin-related gene from the large-scale polymorphism linked to the PML gene.
Gilles F, Goy A, Remache Y, Manova K, Zelenetz AD
Genomics70(3)364-74(2000 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GOLGA6A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GOLGA6A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu31278	NM_001038640.2 Latest version!	Homo sapiens golgin A6 family member A (GOLGA6A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GOLGA6A ( NM_001038640.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001033729.2 Homo sapiens golgin A6 family member A (GOLGA6A), mRNA.

Price & Availability↑

CloneID	OHu31278
Clone ID Related Accession (Same CDS sequence)	NM_001038640.2
Accession Version	NM_001038640.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2082bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	golgin subfamily A member 6A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF263742.1, BC131515.1 and AC013486.12. On Apr 27, 2007 this sequence version replaced NM_001038640.1. ##Evidence-Data-START## Transcript exon combination :: AK292574.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000290438.3/ ENSP00000290438.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTGGCCCC AACCCTACCT CCCTCCCCAC CCCATGATGT TAGAAGAATC TCGACAGAAT 
AAATTGGCAG CAGCCAAGAA AAAGCTAAAA GAATATCAGC AAAGGAAGAG CCCTGGTATT 
CCAGCAGGAG CAAAGACAAA AAAGAAAAAA ACTGACAGTA GCCCTGAGAC AACCACTTCC 
GGTGGTTGCC ACTCACCTGG GGATAGCCAG TACCAAGAAC TAGCAGTAGC CCTGGAGTCA 
AGCTCAGTGA CAATCAGTCA ACTCAATGAA AACATAGAAT CATTGAAACA GCAGAAGAAA 
CAAGTGGAAC ATCAGCTGGA AGAAGCAAAG AAAACAAACA ATGAAATACA CAAAGCACAA 
ATGGAGCGGT TAGAGACAAT CAACATCCTC ACATTGGAAA AGGCAGACTT GAAGACCACC 
CTTTACCATA CTAAACGTGC TGCCCGACAC TTCGAAGAAG AGTCCAAGGA TCTGGCTGGC 
CGCCTGCAAT ACTCCTTACA GCGTATTCAA GAATTGGAGC GGGCTCTCTG TGCTGTGTCT 
ACACAGCAGC AGGAAGAGGA CAGGTCCTCG AGCTGCAGAG AAGCGGTCCT CCAGCGGTGG 
TTACAGCAGA CCATAAAGGA GCGGGCGCTG CTGAACGCAC ACGTGACACA GGTGACAGAG 
TCACTAAAAC AAGTCCAGCT AGAGCGAGAC GAATATGCTA AACACATAAA AGGAGAGAGG 
GCCCGGTGGC AGGAGAGGAT GTGGAAAATG TCGGTGGAGG CTCGAACATT GAAGGAAGAG 
AAGAAGCGTG ACATACATCG GATACAGGAG CTGGAGAGGA GCTTGTCCGA ACTCAAAAAC 
CAGATGGCTG AGCCCCCATC CCTGGCGCCC CCAGCAGTGA CCTCTGTGGT GGAACAGCTA 
CAAGATGAGG CCAAACACCT GAGGCAGGAG GTGGAAGGTC TGGAGGGAAA GCTCCAGTCC 
CAGGTGGAAA ACAATCAGGC CTTGAGTCTC CTTAGCAAGG AACAAAAGCA GAGACTCCAG 
GAGCAGGAGG AGATGCTCCG AGAGCAGGAG GCGCAGAGAG TGCGGGAGCA GGAGAGACTG 
TGTGAACAAA ACGAGAGGCT TCGGGAGCAG CAGAAGACGC TACAGGAGCA GGGTGAGAGG 
CTGCGAAAGC AGGAGCAGAG GCTACGCAAA CAGGAGGAGA GGCTGCGAAA GGAGGAGGAG 
AGGCTGCAAA AGCAGGAAAA GAGGCTGTGG GACCAGGAGG AGAGGCTGTG GAAGAAGGAG 
GAGAGGCTAC AAAAGCAGGA GGAGAGGCTC GCGCTCTCCC AGAACCACAA GCTCGACAAG 
CAGCTGGCCG AGCCACAGTG CAGCTTCGAG GATCTGAACA ACGAGAAAAA GAGCGCACTG 
CAGTTGGAGC AGCAAGTAAA GGAGCTGCAG GAGAAGCTAG ACGAGGAGCA CCTAGAAGCT 
GCCAGCCACC AGAACCAACA GCTAGAGACC CAGCTAAGCC TCGTGGCTCT CCCTGGAGAA 
GGAGATGGAG GACAACATCT GGACAGTGAG GAGGAGGAGG CGCCTCGGCC CACGCCAAAC 
ATCCCAGAGG ACCTGGAGAG CCGGGAGGCC ACGAGCAGCT TTATGGACCT CCCGAAGGAG 
AAGGCGGACG GGACGGAGCA GGTGGAGAGA CGAGAGCTTG GATTCGTCCA GCCTTCTGGA 
GTGACAGACG GCATGAGAGA GTCCTTCACC GTATATGAAA GCCAGGGGGC AGTGCCAAAC 
ACGCGGCACC AGGAGATGGA GGATGTCATC AGGCTGGCCC AGAAGGAGGA GGAGATGAAG 
GTGAAGCTGC TGGAGCTGCA AGAGTTGGTG TTGCCCCTTG TGGGCAACCA TGAGGGGCAT 
GGCAAATTCC TCATCGCTGC CCAGAACCCT GCTGATGAGC CCACTCCAGG GGCCCCAGCC 
CCCCAGGAAC TTGGGGCTGC CGGTGAGCAG GATGTTTTTT ATGAAGTGAG CCTGGACAAC 
AACGTGGAGC CTGCACCAGG AGCGGCCAGG GAGGGTTCTC CCCATGACAA CCCCACTGTA 
CAGCAGATCG TGCAGCTGTC TCCTGTCATG CAGGACACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001033729.2
CDS	42..2123
Translation	MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLLELQELVLPLVGNHEGHGKFLIAAQNPADEPTPGAPAPQELGAAGEQDVFYEVSLDNNVEPAPGAAREGSPHDNPTVQQIVQLSPVMQDT

Target ORF information:

RefSeq Version	NM_001038640.2
Organism	Homo sapiens(human)
Definition	Homo sapiens golgin A6 family member A (GOLGA6A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001038640.2

ORF Insert Sequence:

ATGTGGCCCC AACCCTACCT CCCTCCCCAC CCCATGATGT TAGAAGAATC TCGACAGAAT 
AAATTGGCAG CAGCCAAGAA AAAGCTAAAA GAATATCAGC AAAGGAAGAG CCCTGGTATT 
CCAGCAGGAG CAAAGACAAA AAAGAAAAAA ACTGACAGTA GCCCTGAGAC AACCACTTCC 
GGTGGTTGCC ACTCACCTGG GGATAGCCAG TACCAAGAAC TAGCAGTAGC CCTGGAGTCA 
AGCTCAGTGA CAATCAGTCA ACTCAATGAA AACATAGAAT CATTGAAACA GCAGAAGAAA 
CAAGTGGAAC ATCAGCTGGA AGAAGCAAAG AAAACAAACA ATGAAATACA CAAAGCACAA 
ATGGAGCGGT TAGAGACAAT CAACATCCTC ACATTGGAAA AGGCAGACTT GAAGACCACC 
CTTTACCATA CTAAACGTGC TGCCCGACAC TTCGAAGAAG AGTCCAAGGA TCTGGCTGGC 
CGCCTGCAAT ACTCCTTACA GCGTATTCAA GAATTGGAGC GGGCTCTCTG TGCTGTGTCT 
ACACAGCAGC AGGAAGAGGA CAGGTCCTCG AGCTGCAGAG AAGCGGTCCT CCAGCGGTGG 
TTACAGCAGA CCATAAAGGA GCGGGCGCTG CTGAACGCAC ACGTGACACA GGTGACAGAG 
TCACTAAAAC AAGTCCAGCT AGAGCGAGAC GAATATGCTA AACACATAAA AGGAGAGAGG 
GCCCGGTGGC AGGAGAGGAT GTGGAAAATG TCGGTGGAGG CTCGAACATT GAAGGAAGAG 
AAGAAGCGTG ACATACATCG GATACAGGAG CTGGAGAGGA GCTTGTCCGA ACTCAAAAAC 
CAGATGGCTG AGCCCCCATC CCTGGCGCCC CCAGCAGTGA CCTCTGTGGT GGAACAGCTA 
CAAGATGAGG CCAAACACCT GAGGCAGGAG GTGGAAGGTC TGGAGGGAAA GCTCCAGTCC 
CAGGTGGAAA ACAATCAGGC CTTGAGTCTC CTTAGCAAGG AACAAAAGCA GAGACTCCAG 
GAGCAGGAGG AGATGCTCCG AGAGCAGGAG GCGCAGAGAG TGCGGGAGCA GGAGAGACTG 
TGTGAACAAA ACGAGAGGCT TCGGGAGCAG CAGAAGACGC TACAGGAGCA GGGTGAGAGG 
CTGCGAAAGC AGGAGCAGAG GCTACGCAAA CAGGAGGAGA GGCTGCGAAA GGAGGAGGAG 
AGGCTGCAAA AGCAGGAAAA GAGGCTGTGG GACCAGGAGG AGAGGCTGTG GAAGAAGGAG 
GAGAGGCTAC AAAAGCAGGA GGAGAGGCTC GCGCTCTCCC AGAACCACAA GCTCGACAAG 
CAGCTGGCCG AGCCACAGTG CAGCTTCGAG GATCTGAACA ACGAGAAAAA GAGCGCACTG 
CAGTTGGAGC AGCAAGTAAA GGAGCTGCAG GAGAAGCTAG ACGAGGAGCA CCTAGAAGCT 
GCCAGCCACC AGAACCAACA GCTAGAGACC CAGCTAAGCC TCGTGGCTCT CCCTGGAGAA 
GGAGATGGAG GACAACATCT GGACAGTGAG GAGGAGGAGG CGCCTCGGCC CACGCCAAAC 
ATCCCAGAGG ACCTGGAGAG CCGGGAGGCC ACGAGCAGCT TTATGGACCT CCCGAAGGAG 
AAGGCGGACG GGACGGAGCA GGTGGAGAGA CGAGAGCTTG GATTCGTCCA GCCTTCTGGA 
GTGACAGACG GCATGAGAGA GTCCTTCACC GTATATGAAA GCCAGGGGGC AGTGCCAAAC 
ACGCGGCACC AGGAGATGGA GGATGTCATC AGGCTGGCCC AGAAGGAGGA GGAGATGAAG 
GTGAAGCTGC TGGAGCTGCA AGAGTTGGTG TTGCCCCTTG TGGGCAACCA TGAGGGGCAT 
GGCAAATTCC TCATCGCTGC CCAGAACCCT GCTGATGAGC CCACTCCAGG GGCCCCAGCC 
CCCCAGGAAC TTGGGGCTGC CGGTGAGCAG GATGTTTTTT ATGAAGTGAG CCTGGACAAC 
AACGTGGAGC CTGCACCAGG AGCGGCCAGG GAGGGTTCTC CCCATGACAA CCCCACTGTA 
CAGCAGATCG TGCAGCTGTC TCCTGTCATG CAGGACACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neocentromeres in 15q24-26 map to duplicons which flanked an ancestral centromere in 15q25.
Genome research13(9)2059-68(2003 Sep)
Ventura M,Mudge JM,Palumbo V,Burn S,Blennow E,Pierluigi M,Giorda R,Zuffardi O,Archidiacono N,Jackson MS,Rocchi M

Human chromosome 15q11-q14 regions of rearrangements contain clusters of LCR15 duplicons.
European journal of human genetics : EJHG10(1)26-35(2002 Jan)
Pujana MA,Nadal M,Guitart M,Armengol L,Gratac?s M,Estivill X

A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders.
Cell106(3)367-79(2001 Aug)
Gratac?s M,Nadal M,Mart?n-Santos R,Pujana MA,Gago J,Peral B,Armengol L,Ponsa I,Mir? R,Bulbena A,Estivill X

Additional complexity on human chromosome 15q: identification of a set of newly recognized duplicons (LCR15) on 15q11-q13, 15q24, and 15q26.
Genome research11(1)98-111(2001 Jan)
Pujana MA,Nadal M,Gratac?s M,Peral B,Csiszar K,Gonz?lez-Sarmiento R,Sumoy L,Estivill X

Cloning and characterization of a Golgin-related gene from the large-scale polymorphism linked to the PML gene.
Genomics70(3)364-74(2000 Dec)
Gilles F,Goy A,Remache Y,Manova K,Zelenetz AD

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GOLGA6A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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