APOC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	APOC1
Entrez Gene ID	341
Full Name	apolipoprotein C1
Synonyms	Apo-CI,ApoC-I,apo-CIB,apoC-IB
General protein information	Preferred Names apolipoprotein C1 Names apolipoprotein C-I
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.32
Summary	This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016].
Disorder MIM:	107710

mRNA and Protein(s)

mRNA	Protein	Name
NM_001645.3	NP_001636.1	apolipoprotein C-I precursor
NM_001645.4	NP_001636.1	apolipoprotein C-I precursor
NM_001321065.1	NP_001307994.1	apolipoprotein C-I precursor
NM_001321065.2	NP_001307994.1	apolipoprotein C-I precursor
NM_001321066.2	NP_001307995.1	apolipoprotein C-I precursor
XM_005258855.2	XP_005258912.1	apolipoprotein C-I isoform X1
NM_001321066.1	NP_001307995.1	apolipoprotein C-I precursor
NM_001645.5	NP_001636.1	apolipoprotein C-I precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	APOC1A	XP_001148136.1
Homo sapiens (human)	APOC1	NP_001636.1

Gene Ontology
Bibliography

Related articles in PubMed

Apolipoprotein C-I Polymorphism and Its Association with Serum Lipid Levels and Longevity in the Bama Population.
Li Y, Huang Y, Liang X, Long B, Chen S, Lian J, Wei Y, Zhang Z, Qin J
International journal of environmental research and public health14(5)(2017 May)

Functional analysis of the endogenous retroviral promoter of the human endothelin B receptor gene.
Landry JR, Mager DL
Journal of virology77(13)7459-66(2003 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Among white women, three single nucleotide polymorphisms (SNPs) (rs2075650 [TOMM40], rs4420638 [APOC1], and rs429358 [APOE]) were significantly associated with survival to 90 years after correction for multiple testing (p < .001); rs4420638 and rs429358 were also significantly associated with healthy aging (p = .02). In African American women, no SNP was associated with longevity. In Hispanic women, 7 SNPs in linkage dise
Title: Replication of Genome-Wide Association Study Findings of Longevity in White, African American, and Hispanic Women: The Women's Health Initiative.

ApoC-I polymorphism might be one of the genetic factors of longevity in Bama; the ApoC-I rs4420638 and rs584007 SNPs are associated with serum triglycerides and high-density lipoprotein-cholesterol levels in the longevous population
Title: Apolipoprotein C-I Polymorphism and Its Association with Serum Lipid Levels and Longevity in the Bama Population.

APOC1 expression induces glomerulosclerosis, potentially by increasing the cytokine response in macrophages.
Title: Apolipoprotein C-I plays a role in the pathogenesis of glomerulosclerosis.

People with allelic variation in four genes related to cardiovascular diseases and metabolism were more likely to die: apolipoprotein (APO)C1 GG and AG carriers, APOE varepsilon4 carriers, insulin-degrading enzyme (IDE) TC carriers, and phosphatidylinositol 3-kinase (PI3KCB) GG carriers.
Title: Effect of the Interplay Between Genetic and Behavioral Risks on Survival After Age 75.

Common single-nucleotide polymorphism in the APOC1/APOE region, previously found to be associated with protective levels of cholesterol and lower cardiovascular risk, may be associated with ideal health.
Title: Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies.

The following APOC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APOC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24784	NM_001321065.2 Latest version!	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu24784	NM_001321066.2 Latest version!	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu24784	NM_001645.5 Latest version!	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu24784	XM_005258855.2 Latest version!	Homo sapiens apolipoprotein C-I (APOC1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu24784	NM_001645.3	Homo sapiens apolipoprotein C-I (APOC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu24784	NM_001321065.1	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu24784	NM_001321066.1	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu24784	NM_001645.4	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

APOC1 ( NM_001645.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001636.1 Homo sapiens apolipoprotein C-I (APOC1), mRNA.

Price & Availability↑

CloneID	OHu24784
Clone ID Related Accession (Same CDS sequence)	NM_001645.3 , NM_001645.4 , NM_001321065.1 , NM_001321065.2 , NM_001321066.2 , XM_005258855.2 , NM_001321066.1 , NM_001645.5
Accession Version	NM_001645.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-05-20
Organism	Homo sapiens(Human)
Product	apolipoprotein C-I precursor
Comment

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001636.1
Translation	MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS

Target ORF information:

RefSeq Version	NM_001645.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens apolipoprotein C-I (APOC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001645.3

ORF Insert Sequence:

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APOC1 ( NM_001645.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001636.1 Homo sapiens apolipoprotein C1 (APOC1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24784
Clone ID Related Accession (Same CDS sequence)	NM_001645.3 , NM_001645.4 , NM_001321065.1 , NM_001321065.2 , NM_001321066.2 , XM_005258855.2 , NM_001321066.1 , NM_001645.5
Accession Version	NM_001645.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	apolipoprotein C-I precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC011481.4, AK312036.1 and CA445083.1. This sequence is a reference standard in the RefSeqGene project. On Mar 18, 2016 this sequence version replaced NM_001645.3. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. This transcript is expressed primarily in the liver. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG493017.1, CD365683.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001636.1
CDS	200..451
Translation	MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS

Target ORF information:

RefSeq Version	NM_001645.4
Organism	Homo sapiens(human)
Definition	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001645.4

ORF Insert Sequence:

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APOC1 ( NM_001321065.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307994.1 Homo sapiens apolipoprotein C1 (APOC1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24784
Clone ID Related Accession (Same CDS sequence)	NM_001645.3 , NM_001645.4 , NM_001321065.1 , NM_001321065.2 , NM_001321066.2 , XM_005258855.2 , NM_001321066.1 , NM_001645.5
Accession Version	NM_001321065.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	apolipoprotein C-I precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA482306.1, AK225971.1, AC011481.4 and CA445083.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. The 5' end of this transcript contains long terminal repeat (LTR) sequence and initiates from an LTR promoter with weak activity in several cell types, including colon, brain lung, liver, kidney and placenta.(PMID: 11054415). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AA976838.1, AK225971.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307994.1
CDS	264..515
Translation	MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS

Target ORF information:

RefSeq Version	NM_001321065.1
Organism	Homo sapiens(human)
Definition	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321065.1

ORF Insert Sequence:

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APOC1 ( NM_001321065.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307994.1 Homo sapiens apolipoprotein C1 (APOC1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24784
Clone ID Related Accession (Same CDS sequence)	NM_001645.3 , NM_001645.4 , NM_001321065.1 , NM_001321065.2 , NM_001321066.2 , XM_005258855.2 , NM_001321066.1 , NM_001645.5
Accession Version	NM_001321065.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Homo sapiens(human)
Product	apolipoprotein C-I precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK225971.1 and AC011481.4. On Jun 2, 2019 this sequence version replaced NM_001321065.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. The 5' end of this transcript contains long terminal repeat (LTR) sequence and initiates from an LTR promoter with weak activity in several cell types, including colon, brain lung, liver, kidney and placenta.(PMID: 11054415). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225971.1, BP304001.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307994.1
CDS	186..437
Translation	MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS

Target ORF information:

RefSeq Version	NM_001321065.2
Organism	Homo sapiens(human)
Definition	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321065.2

ORF Insert Sequence:

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APOC1 ( NM_001321066.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307995.1 Homo sapiens apolipoprotein C1 (APOC1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu24784
Clone ID Related Accession (Same CDS sequence)	NM_001645.3 , NM_001645.4 , NM_001321065.1 , NM_001321065.2 , NM_001321066.2 , XM_005258855.2 , NM_001321066.1 , NM_001645.5
Accession Version	NM_001321066.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Homo sapiens(human)
Product	apolipoprotein C-I precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC055093.1 and CA445083.1. On Jun 3, 2019 this sequence version replaced NM_001321066.1. Transcript Variant: This variant (3) encodes the longest transcript. Variants 1, 2 and 3 encode the same protein. The 5' end of this transcript contains long terminal repeat (LTR) sequence and initiates from an LTR promoter with weak activity in several cell types, including colon, brain lung, liver, kidney and placenta.(PMID: 11054415). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP304092.1, DB503502.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307995.1
CDS	248..499
Translation	MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS

Target ORF information:

RefSeq Version	NM_001321066.2
Organism	Homo sapiens(human)
Definition	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321066.2

ORF Insert Sequence:

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APOC1 ( NM_001321066.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307995.1 Homo sapiens apolipoprotein C1 (APOC1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu24784
Clone ID Related Accession (Same CDS sequence)	NM_001645.3 , NM_001645.4 , NM_001321065.1 , NM_001321065.2 , NM_001321066.2 , XM_005258855.2 , NM_001321066.1 , NM_001645.5
Accession Version	NM_001321066.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	apolipoprotein C-I precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA482306.1, BC055093.1 and CA445083.1. On Mar 18, 2016 this sequence version replaced XM_005258855.2. Transcript Variant: This variant (3) encodes the longest transcript. Variants 1, 2 and 3 encode the same protein. The 5' end of this transcript contains long terminal repeat (LTR) sequence and initiates from an LTR promoter with weak activity in several cell types, including colon, brain lung, liver, kidney and placenta.(PMID: 11054415). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA482306.1, BC055093.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307995.1
CDS	326..577
Translation	MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS

Target ORF information:

RefSeq Version	NM_001321066.1
Organism	Homo sapiens(human)
Definition	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321066.1

ORF Insert Sequence:

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APOC1 ( NM_001645.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001636.1 Homo sapiens apolipoprotein C1 (APOC1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24784
Clone ID Related Accession (Same CDS sequence)	NM_001645.3 , NM_001645.4 , NM_001321065.1 , NM_001321065.2 , NM_001321066.2 , XM_005258855.2 , NM_001321066.1 , NM_001645.5
Accession Version	NM_001645.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	apolipoprotein C-I precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC011481.4, AK312036.1 and CA445083.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_001645.4. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. This transcript is expressed primarily in the liver. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD365683.1, BU603900.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001636.1
CDS	147..398
Translation	MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS

Target ORF information:

RefSeq Version	NM_001645.5
Organism	Homo sapiens(human)
Definition	Homo sapiens apolipoprotein C1 (APOC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001645.5

ORF Insert Sequence:

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APOC1 ( XM_005258855.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005258912.1 Homo sapiens apolipoprotein C-I (APOC1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu24784
Clone ID Related Accession (Same CDS sequence)	NM_001645.3 , NM_001645.4 , NM_001321065.1 , NM_001321065.2 , NM_001321066.2 , XM_005258855.2 , NM_001321066.1 , NM_001645.5
Accession Version	XM_005258855.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	apolipoprotein C-I isoform X1
Comment

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258912.1
Translation	MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS

Target ORF information:

RefSeq Version	XM_005258855.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens apolipoprotein C-I (APOC1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258855.2

ORF Insert Sequence:

ATGAGGCTCT TCCTGTCGCT CCCGGTCCTG GTGGTGGTTC TGTCGATCGT CTTGGAAGGC 
CCAGCCCCAG CCCAGGGGAC CCCAGACGTC TCCAGTGCCT TGGATAAGCT GAAGGAGTTT 
GGAAACACAC TGGAGGACAA GGCTCGGGAA CTCATCAGCC GCATCAAACA GAGTGAACTT 
TCTGCCAAGA TGCGGGAGTG GTTTTCAGAG ACATTTCAGA AAGTGAAGGA GAAACTCAAG 
ATTGACTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Apolipoprotein C-I Polymorphism and Its Association with Serum Lipid Levels and Longevity in the Bama Population.
International journal of environmental research and public health14(5)(2017 May)
Li Y,Huang Y,Liang X,Long B,Chen S,Lian J,Wei Y,Zhang Z,Qin J

Functional analysis of the endogenous retroviral promoter of the human endothelin B receptor gene.
Journal of virology77(13)7459-66(2003 Jul)
Landry JR,Mager DL

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APOC1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

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ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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