CYP26C1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP26C1
Entrez Gene ID	340665
Full Name	cytochrome P450 family 26 subfamily C member 1
Synonyms	FFDD4
General protein information	Preferred Names cytochrome P450 family 26 subfamily C member 1 Names cytochrome P450 26C1 cytochrome P450, family 26, subfamily C, polypeptide 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q23.33
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008].
Disorder MIM:	608428
Disorder Html:	Focal facial dermal dysplasia 4, 614974 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_183374.3	NP_899230.2	cytochrome P450 26C1
NM_183374.2	NP_899230.2	cytochrome P450 26C1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CYP26C1	XP_002698522.1
Pan troglodytes (chimpanzee)	LOC100610581	XP_003312734.1
Danio rerio (zebrafish)	cyp26c1	NP_001025122.2
Mus musculus (house mouse)	Cyp26c1	NP_001098671.1
Rattus norvegicus (Norway rat)	Cyp26c1	XP_217935.3
Homo sapiens (human)	CYP26C1	NP_899230.2
Gallus gallus (chicken)	CYP26C1	XP_421678.4
Arabidopsis thaliana (thale cress)	CYP718	NP_181813.1
Xenopus tropicalis (tropical clawed frog)	LOC100489980	XP_002939137.2

Gene Ontology
Bibliography

Related articles in PubMed

Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency.
Montalbano A, Juergensen L, Roeth R, Weiss B, Fukami M, Fricke-Otto S, Binder G, Ogata T, Decker E, Nuernberg G, Hassel D, Rappold GA
EMBO molecular medicine8(12)1455-1469(2016 12)

Elevated expression of the retinoic acid-metabolizing enzyme CYP26C1 in primary breast carcinomas.
Osanai M, Lee GH
Medical molecular morphology49(1)22-7(2016 Mar)

Focal facial dermal dysplasia, type IV, is caused by mutations in CYP26C1.
Slavotinek AM, Mehrotra P, Nazarenko I, Tang PL, Lao R, Cameron D, Li B, Chu C, Chou C, Marqueling AL, Yahyavi M, Cordoro K, Frieden I, Glaser T, Prescott T, Morren MA, Devriendt K, Kwok PY, Petkovich M, Desnick RJ
Human molecular genetics22(4)696-703(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Together, these findings describe CYP26C1 as the first genetic modifier for SHOX deficiency.
Title: Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency.

Elevated expression of CYP26C1 in primary breast carcinomas
Title: Elevated expression of the retinoic acid-metabolizing enzyme CYP26C1 in primary breast carcinomas.

Focal facial dermal dysplasia, type IV results from the loss of function mutations in CYP26C1.
Title: Focal facial dermal dysplasia, type IV, is caused by mutations in CYP26C1.

CYP26A1 and CYP26C1 play a pivotal role in the pathogenesis of nonsyndromic bilateral and unilateral optic nerve aplasia.
Title: Nonsyndromic bilateral and unilateral optic nerve aplasia: first familial occurrence and potential implication of CYP26A1 and CYP26C1 genes.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Positive association between ALDH1A2 and schizophrenia in the Chinese population.

The following CYP26C1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP26C1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19077	NM_183374.3 Latest version!	Homo sapiens cytochrome P450 family 26 subfamily C member 1 (CYP26C1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$300.30 $429.00
View Old Accession Versions >>
OHu19077	NM_183374.2	Homo sapiens cytochrome P450 family 26 subfamily C member 1 (CYP26C1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$300.30 $429.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP26C1 ( NM_183374.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_899230.2 Homo sapiens cytochrome P450 family 26 subfamily C member 1 (CYP26C1), mRNA.

Price & Availability↑

CloneID	OHu19077
Clone ID Related Accession (Same CDS sequence)	NM_183374.3 , NM_183374.2
Accession Version	NM_183374.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	cytochrome P450 26C1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL358613.16 and AY356349.1. This sequence is a reference standard in the RefSeqGene project. On Oct 5, 2018 this sequence version replaced NM_183374.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY356349.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2148874 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000651965.1/ ENSP00000498424.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTTCCCTT GGGGGCTGAG CTGCCTGTCA GTGCTGGGGG CGGCGGGCAC TGCTCTCCTG 
TGCGCGGGCC TGCTGCTCAG CCTGGCCCAG CACCTCTGGA CCCTCCGCTG GATGCTGAGC 
CGGGACCGGG CCTCCACCCT GCCTCTGCCC AAGGGCTCCA TGGGGTGGCC CTTCTTCGGC 
GAAACGCTGC ACTGGTTAGT TCAGGGCTCG CGCTTCCACA GTTCTCGCCG AGAGCGCTAT 
GGGACAGTGT TCAAGACGCA CCTGCTGGGC AGGCCAGTGA TCCGCGTGAG CGGCGCGGAG 
AACGTGCGCA CCATCCTGCT GGGCGAGCAC CGCCTGGTGC GCAGCCAGTG GCCGCAGAGT 
GCGCACATCC TGCTGGGCTC GCACACACTG CTAGGTGCGG TCGGCGAGCC GCACCGGCGG 
CGGCGCAAGG TCCTGGCGCG CGTGTTCAGC CGCGCCGCGC TGGAGCGCTA CGTGCCGCGC 
CTGCAGGGGG CGCTGCGGCA TGAGGTGCGC TCCTGGTGCG CGGCGGGCGG GCCGGTCTCA 
GTCTACGACG CCTCCAAAGC GCTCACCTTC CGCATGGCCG CGCGCATCCT GCTGGGGTTG 
CGGCTGGACG AGGCGCAGTG CGCCACGCTG GCCCGGACCT TCGAGCAGCT CGTGGAGAAC 
CTCTTCTCAC TGCCTCTGGA CGTTCCCTTC AGTGGCCTAC GCAAGGGCAT CCGGGCAAGG 
GACCAGCTGC ATCGGCACCT GGAGGGGGCC ATTTCTGAGA AGCTTCACGA GGACAAGGCT 
GCAGAGCCGG GTGATGCCCT CGACCTAATC ATTCACAGTG CAAGGGAGCT GGGCCATGAG 
CCCTCCATGC AGGAGCTGAA GGAGTCGGCT GTGGAGCTCC TCTTCGCCGC CTTCTTCACC 
ACGGCCAGTG CCAGCACCTC GCTCGTCCTG CTGCTACTGC AGCATCCGGC GGCCATCGCC 
AAGATTCGGG AGGAGCTGGT GGCGCAGGGG CTGGGGCGCG CGTGCGGCTG CGCGCCCGGG 
GCCGCTGGGG GCAGCGAGGG GCCCCCGCCC GACTGCGGCT GCGAGCCCGA CCTCAGCCTC 
GCGGCGCTGG GCCGTCTGCG CTACGTCGAC TGCGTGGTCA AGGAGGTGCT GCGCCTCCTG 
CCGCCAGTGT CCGGGGGCTA CCGCACCGCC CTGCGCACCT TCGAGCTCGA CGGCTACCAG 
ATCCCCAAGG GCTGGAGCGT GATGTATAGC ATCCGGGACA CGCACGAGAC GGCTGCGGTG 
TACCGCAGCC CTCCCGAAGG CTTCGATCCA GAGCGCTTCG GCGCAGCGCG CGAAGATTCC 
CGGGGCGCCT CCAGCCGCTT CCATTACATC CCGTTCGGCG GCGGTGCGCG CAGCTGCCTC 
GGCCAGGAGC TGGCGCAAGC CGTGCTCCAG CTGCTAGCTG TGGAGCTAGT GCGCACCGCG 
CGCTGGGAAC TGGCCACACC CGCCTTCCCC GCCATGCAGA CGGTGCCCAT CGTGCACCCA 
GTGGACGGGC TGCGGCTCTT TTTCCACCCC CTCACGCCTT CGGTTGCGGG GAATGGGCTA 
TGCCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_899230.2
CDS	467..2035
Translation	MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL

Target ORF information:

RefSeq Version	NM_183374.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 26 subfamily C member 1 (CYP26C1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183374.3

ORF Insert Sequence:

ATGTTCCCTT GGGGGCTGAG CTGCCTGTCA GTGCTGGGGG CGGCGGGCAC TGCTCTCCTG 
TGCGCGGGCC TGCTGCTCAG CCTGGCCCAG CACCTCTGGA CCCTCCGCTG GATGCTGAGC 
CGGGACCGGG CCTCCACCCT GCCTCTGCCC AAGGGCTCCA TGGGGTGGCC CTTCTTCGGC 
GAAACGCTGC ACTGGTTAGT TCAGGGCTCG CGCTTCCACA GTTCTCGCCG AGAGCGCTAT 
GGGACAGTGT TCAAGACGCA CCTGCTGGGC AGGCCAGTGA TCCGCGTGAG CGGCGCGGAG 
AACGTGCGCA CCATCCTGCT GGGCGAGCAC CGCCTGGTGC GCAGCCAGTG GCCGCAGAGT 
GCGCACATCC TGCTGGGCTC GCACACACTG CTAGGTGCGG TCGGCGAGCC GCACCGGCGG 
CGGCGCAAGG TCCTGGCGCG CGTGTTCAGC CGCGCCGCGC TGGAGCGCTA CGTGCCGCGC 
CTGCAGGGGG CGCTGCGGCA TGAGGTGCGC TCCTGGTGCG CGGCGGGCGG GCCGGTCTCA 
GTCTACGACG CCTCCAAAGC GCTCACCTTC CGCATGGCCG CGCGCATCCT GCTGGGGTTG 
CGGCTGGACG AGGCGCAGTG CGCCACGCTG GCCCGGACCT TCGAGCAGCT CGTGGAGAAC 
CTCTTCTCAC TGCCTCTGGA CGTTCCCTTC AGTGGCCTAC GCAAGGGCAT CCGGGCAAGG 
GACCAGCTGC ATCGGCACCT GGAGGGGGCC ATTTCTGAGA AGCTTCACGA GGACAAGGCT 
GCAGAGCCGG GTGATGCCCT CGACCTAATC ATTCACAGTG CAAGGGAGCT GGGCCATGAG 
CCCTCCATGC AGGAGCTGAA GGAGTCGGCT GTGGAGCTCC TCTTCGCCGC CTTCTTCACC 
ACGGCCAGTG CCAGCACCTC GCTCGTCCTG CTGCTACTGC AGCATCCGGC GGCCATCGCC 
AAGATTCGGG AGGAGCTGGT GGCGCAGGGG CTGGGGCGCG CGTGCGGCTG CGCGCCCGGG 
GCCGCTGGGG GCAGCGAGGG GCCCCCGCCC GACTGCGGCT GCGAGCCCGA CCTCAGCCTC 
GCGGCGCTGG GCCGTCTGCG CTACGTCGAC TGCGTGGTCA AGGAGGTGCT GCGCCTCCTG 
CCGCCAGTGT CCGGGGGCTA CCGCACCGCC CTGCGCACCT TCGAGCTCGA CGGCTACCAG 
ATCCCCAAGG GCTGGAGCGT GATGTATAGC ATCCGGGACA CGCACGAGAC GGCTGCGGTG 
TACCGCAGCC CTCCCGAAGG CTTCGATCCA GAGCGCTTCG GCGCAGCGCG CGAAGATTCC 
CGGGGCGCCT CCAGCCGCTT CCATTACATC CCGTTCGGCG GCGGTGCGCG CAGCTGCCTC 
GGCCAGGAGC TGGCGCAAGC CGTGCTCCAG CTGCTAGCTG TGGAGCTAGT GCGCACCGCG 
CGCTGGGAAC TGGCCACACC CGCCTTCCCC GCCATGCAGA CGGTGCCCAT CGTGCACCCA 
GTGGACGGGC TGCGGCTCTT TTTCCACCCC CTCACGCCTT CGGTTGCGGG GAATGGGCTA 
TGCCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP26C1 ( NM_183374.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_899230.2 Homo sapiens cytochrome P450 family 26 subfamily C member 1 (CYP26C1), mRNA.

Price & Availability↑

CloneID	OHu19077
Clone ID Related Accession (Same CDS sequence)	NM_183374.3 , NM_183374.2
Accession Version	NM_183374.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	cytochrome P450 26C1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY356349.1 and AL358613.16. This sequence is a reference standard in the RefSeqGene project. On Apr 28, 2005 this sequence version replaced NM_183374.1. ##Evidence-Data-START## Transcript exon combination :: AY356349.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA2148874 [ECO:0000350] ##Evidence-Data-END##

ATGTTCCCTT GGGGGCTGAG CTGCCTGTCA GTGCTGGGGG CGGCGGGCAC TGCTCTCCTG 
TGCGCGGGCC TGCTGCTCAG CCTGGCCCAG CACCTCTGGA CCCTCCGCTG GATGCTGAGC 
CGGGACCGGG CCTCCACCCT GCCTCTGCCC AAGGGCTCCA TGGGGTGGCC CTTCTTCGGC 
GAAACGCTGC ACTGGTTAGT TCAGGGCTCG CGCTTCCACA GTTCTCGCCG AGAGCGCTAT 
GGGACAGTGT TCAAGACGCA CCTGCTGGGC AGGCCAGTGA TCCGCGTGAG CGGCGCGGAG 
AACGTGCGCA CCATCCTGCT GGGCGAGCAC CGCCTGGTGC GCAGCCAGTG GCCGCAGAGT 
GCGCACATCC TGCTGGGCTC GCACACACTG CTAGGTGCGG TCGGCGAGCC GCACCGGCGG 
CGGCGCAAGG TCCTGGCGCG CGTGTTCAGC CGCGCCGCGC TGGAGCGCTA CGTGCCGCGC 
CTGCAGGGGG CGCTGCGGCA TGAGGTGCGC TCCTGGTGCG CGGCGGGCGG GCCGGTCTCA 
GTCTACGACG CCTCCAAAGC GCTCACCTTC CGCATGGCCG CGCGCATCCT GCTGGGGTTG 
CGGCTGGACG AGGCGCAGTG CGCCACGCTG GCCCGGACCT TCGAGCAGCT CGTGGAGAAC 
CTCTTCTCAC TGCCTCTGGA CGTTCCCTTC AGTGGCCTAC GCAAGGGCAT CCGGGCAAGG 
GACCAGCTGC ATCGGCACCT GGAGGGGGCC ATTTCTGAGA AGCTTCACGA GGACAAGGCT 
GCAGAGCCGG GTGATGCCCT CGACCTAATC ATTCACAGTG CAAGGGAGCT GGGCCATGAG 
CCCTCCATGC AGGAGCTGAA GGAGTCGGCT GTGGAGCTCC TCTTCGCCGC CTTCTTCACC 
ACGGCCAGTG CCAGCACCTC GCTCGTCCTG CTGCTACTGC AGCATCCGGC GGCCATCGCC 
AAGATTCGGG AGGAGCTGGT GGCGCAGGGG CTGGGGCGCG CGTGCGGCTG CGCGCCCGGG 
GCCGCTGGGG GCAGCGAGGG GCCCCCGCCC GACTGCGGCT GCGAGCCCGA CCTCAGCCTC 
GCGGCGCTGG GCCGTCTGCG CTACGTCGAC TGCGTGGTCA AGGAGGTGCT GCGCCTCCTG 
CCGCCAGTGT CCGGGGGCTA CCGCACCGCC CTGCGCACCT TCGAGCTCGA CGGCTACCAG 
ATCCCCAAGG GCTGGAGCGT GATGTATAGC ATCCGGGACA CGCACGAGAC GGCTGCGGTG 
TACCGCAGCC CTCCCGAAGG CTTCGATCCA GAGCGCTTCG GCGCAGCGCG CGAAGATTCC 
CGGGGCGCCT CCAGCCGCTT CCATTACATC CCGTTCGGCG GCGGTGCGCG CAGCTGCCTC 
GGCCAGGAGC TGGCGCAAGC CGTGCTCCAG CTGCTAGCTG TGGAGCTAGT GCGCACCGCG 
CGCTGGGAAC TGGCCACACC CGCCTTCCCC GCCATGCAGA CGGTGCCCAT CGTGCACCCA 
GTGGACGGGC TGCGGCTCTT TTTCCACCCC CTCACGCCTT CGGTTGCGGG GAATGGGCTA 
TGCCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_899230.2
CDS	1..1569
Translation	MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL

Target ORF information:

RefSeq Version	NM_183374.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 26 subfamily C member 1 (CYP26C1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183374.2

ORF Insert Sequence:

ATGTTCCCTT GGGGGCTGAG CTGCCTGTCA GTGCTGGGGG CGGCGGGCAC TGCTCTCCTG 
TGCGCGGGCC TGCTGCTCAG CCTGGCCCAG CACCTCTGGA CCCTCCGCTG GATGCTGAGC 
CGGGACCGGG CCTCCACCCT GCCTCTGCCC AAGGGCTCCA TGGGGTGGCC CTTCTTCGGC 
GAAACGCTGC ACTGGTTAGT TCAGGGCTCG CGCTTCCACA GTTCTCGCCG AGAGCGCTAT 
GGGACAGTGT TCAAGACGCA CCTGCTGGGC AGGCCAGTGA TCCGCGTGAG CGGCGCGGAG 
AACGTGCGCA CCATCCTGCT GGGCGAGCAC CGCCTGGTGC GCAGCCAGTG GCCGCAGAGT 
GCGCACATCC TGCTGGGCTC GCACACACTG CTAGGTGCGG TCGGCGAGCC GCACCGGCGG 
CGGCGCAAGG TCCTGGCGCG CGTGTTCAGC CGCGCCGCGC TGGAGCGCTA CGTGCCGCGC 
CTGCAGGGGG CGCTGCGGCA TGAGGTGCGC TCCTGGTGCG CGGCGGGCGG GCCGGTCTCA 
GTCTACGACG CCTCCAAAGC GCTCACCTTC CGCATGGCCG CGCGCATCCT GCTGGGGTTG 
CGGCTGGACG AGGCGCAGTG CGCCACGCTG GCCCGGACCT TCGAGCAGCT CGTGGAGAAC 
CTCTTCTCAC TGCCTCTGGA CGTTCCCTTC AGTGGCCTAC GCAAGGGCAT CCGGGCAAGG 
GACCAGCTGC ATCGGCACCT GGAGGGGGCC ATTTCTGAGA AGCTTCACGA GGACAAGGCT 
GCAGAGCCGG GTGATGCCCT CGACCTAATC ATTCACAGTG CAAGGGAGCT GGGCCATGAG 
CCCTCCATGC AGGAGCTGAA GGAGTCGGCT GTGGAGCTCC TCTTCGCCGC CTTCTTCACC 
ACGGCCAGTG CCAGCACCTC GCTCGTCCTG CTGCTACTGC AGCATCCGGC GGCCATCGCC 
AAGATTCGGG AGGAGCTGGT GGCGCAGGGG CTGGGGCGCG CGTGCGGCTG CGCGCCCGGG 
GCCGCTGGGG GCAGCGAGGG GCCCCCGCCC GACTGCGGCT GCGAGCCCGA CCTCAGCCTC 
GCGGCGCTGG GCCGTCTGCG CTACGTCGAC TGCGTGGTCA AGGAGGTGCT GCGCCTCCTG 
CCGCCAGTGT CCGGGGGCTA CCGCACCGCC CTGCGCACCT TCGAGCTCGA CGGCTACCAG 
ATCCCCAAGG GCTGGAGCGT GATGTATAGC ATCCGGGACA CGCACGAGAC GGCTGCGGTG 
TACCGCAGCC CTCCCGAAGG CTTCGATCCA GAGCGCTTCG GCGCAGCGCG CGAAGATTCC 
CGGGGCGCCT CCAGCCGCTT CCATTACATC CCGTTCGGCG GCGGTGCGCG CAGCTGCCTC 
GGCCAGGAGC TGGCGCAAGC CGTGCTCCAG CTGCTAGCTG TGGAGCTAGT GCGCACCGCG 
CGCTGGGAAC TGGCCACACC CGCCTTCCCC GCCATGCAGA CGGTGCCCAT CGTGCACCCA 
GTGGACGGGC TGCGGCTCTT TTTCCACCCC CTCACGCCTT CGGTTGCGGG GAATGGGCTA 
TGCCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency.
EMBO molecular medicine8(12)1455-1469(2016 12)
Montalbano A,Juergensen L,Roeth R,Weiss B,Fukami M,Fricke-Otto S,Binder G,Ogata T,Decker E,Nuernberg G,Hassel D,Rappold GA

Elevated expression of the retinoic acid-metabolizing enzyme CYP26C1 in primary breast carcinomas.
Medical molecular morphology49(1)22-7(2016 Mar)
Osanai M,Lee GH

Focal facial dermal dysplasia, type IV, is caused by mutations in CYP26C1.
Human molecular genetics22(4)696-703(2013 Feb)
Slavotinek AM,Mehrotra P,Nazarenko I,Tang PL,Lao R,Cameron D,Li B,Chu C,Chou C,Marqueling AL,Yahyavi M,Cordoro K,Frieden I,Glaser T,Prescott T,Morren MA,Devriendt K,Kwok PY,Petkovich M,Desnick RJ

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CYP26C1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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