UNCX cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UNCX
Entrez Gene ID	340260
Full Name	UNC homeobox
Synonyms	UNCX4.1
General protein information	Preferred Names UNC homeobox Names homeobox protein unc-4 homolog UNC homeobox protein Unc4.1 homeobox homeobox protein Uncx4.1 truncated UNCX homeobox protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p22.3
Summary	This gene encodes a homeobox transcription factor that is involved in somitogenesis and neurogenesis and is required for the maintenance and differentiation of specific elements of the axial skeleton. This gene also plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and deliver hormones that control peripheral functions. The expression of this gene is associated with an increased frequency of acute myeloid leukemia. [provided by RefSeq, Jul 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001080461.2	NP_001073930.1	homeobox protein unc-4 homolog
NM_001080461.1	NP_001073930.1	homeobox protein unc-4 homolog
NM_001080461.3	NP_001073930.1	homeobox protein unc-4 homolog

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Uncx	NP_038730.1
Rattus norvegicus (Norway rat)	Uncx	NP_058875.1
Gallus gallus (chicken)	UNCX	XP_414766.3
Homo sapiens (human)	UNCX	NP_001073930.1
Danio rerio (zebrafish)	uncx4.1	NP_001018616.2
	LOC719091	XP_001112733.2
Canis lupus familiaris (dog)	UNCX	XP_548725.3
Danio rerio (zebrafish)	uncx	XP_005164261.1
Xenopus tropicalis (tropical clawed frog)	LOC100492016	XP_002938457.1

Gene Ontology
Bibliography

Related articles in PubMed

Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells.
Daniele G, Simonetti G, Fusilli C, Iacobucci I, Lonoce A, Palazzo A, Lomiento M, Mammoli F, Marsano RM, Marasco E, Mantovani V, Quentmeier H, Drexler HG, Ding J, Palumbo O, Carella M, Nadarajah N, Perricone M, Ottaviani E, Baldazzi C, Testoni N, Papayannidis C, Ferrari S, Mazza T, Martinelli G, Storlazzi CT
Haematologica102(7)1204-1214(2017 Jul)

Detection of Missing Proteins Using the PRIDE Database as a Source of Mass Spectrometry Evidence.
Garin-Muga A, Odriozola L, Mart?nez-Val A, Del Toro N, Mart?nez R, Molina M, Cantero L, Rivera R, Garrido N, Dominguez F, Sanchez Del Pino MM, Vizca?no JA, Corrales FJ, Segura V
Journal of proteome research15(11)4101-4115(2016 Nov)

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS, , , Albrecht E, , Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T
Nature genetics44(8)904-9(2012 Jul)

Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men.
Irvin MR, Shrestha S, Chen YD, Wiener HW, Haritunians T, Vaughan LK, Tiwari HK, Taylor KD, Scherzer R, Saag MS, Grunfeld C, Rotter JI, Arnett DK
Pharmacogenetics and genomics21(12)798-807(2011 Dec)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following UNCX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UNCX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29926	NM_001080461.3 Latest version!	Homo sapiens UNC homeobox (UNCX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu29926	NM_001080461.1	Homo sapiens UNC homeobox (UNCX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu29926	NM_001080461.2	Homo sapiens UNC homeobox (UNCX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UNCX ( NM_001080461.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073930.1 Homo sapiens UNC homeobox (UNCX), mRNA.

Price & Availability↑

CloneID	OHu29926
Clone ID Related Accession (Same CDS sequence)	NM_001080461.2 , NM_001080461.1 , NM_001080461.3
Accession Version	NM_001080461.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1596bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-09
Organism	Homo sapiens(human)
Product	homeobox protein unc-4 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073094.11. On Jul 19, 2017 this sequence version replaced NM_001080461.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. COMPLETENESS: complete on the 3' end.

ATGATGGACG GCCGCCTCCT GGAACACCCG CATGCCCAGT TCGGGGGCTC GCTGGGCGGC 
GTGGTGGGCT TCCCCTACCC GCTGGGCCAC CACCACGTGT ACGAGCTGGC CGGGCACCAG 
CTGCAGTCGG CCGCCGCCGC CGCCTCGGTG CCCTTCTCCA TCGACGGCCT GCTCGGGGGC 
TCGTGCGCCG CCGCCGCCTC GGTGGTCAAC CCCACGCCGC TGCTGCCAGC CGCCTGCGGG 
GTCGGCGGGG ACGGCCAGCC CTTCAAGCTG TCAGACTCGG GGGACCCGGA CAAGGAGAGC 
CCGGGCTGCA AGCGGCGGCG CACCCGCACC AACTTCACCG GCTGGCAGCT GGAGGAGCTG 
GAGAAGGCGT TCAACGAGAG CCACTATCCC GACGTGTTCA TGCGCGAGGC GCTGGCGCTG 
CGCCTAGACC TGGTCGAGTC CCGAGTTCAG GTCTGGTTCC AAAACCGCCG GGCCAAGTGG 
AGGAAGAAGG AGAACACGAA AAAGGGCCCG GGGCGGCCGG CGCACAACTC GCACCCGACC 
ACGTGCAGCG GCGAGCCCAT GGACCCGGAG GAGATCGCGC GCAAGGAGCT GGAGAAGATG 
GAGAAGAAGA AGCGCAAGCA CGAGAAGAAG CTGCTGAAGA GCCAGGGCCG CCACTTGCAC 
TCGCCCGGCG GCCTGTCCCT GCACAGCGCG CCCAGCTCCG ACAGCGACAG CGGCGGCGGC 
GGCCTGTCTC CGGAGCCGCC CGAGCCGCCG CCGCCCGCCG CCAAGGGCCC CGGAGCGCAC 
GCCTCGGGCG CCGCGGGGAC CGCGCCCGCC CCTCCCGGCG AGCCGCCTGC ACCCGGCACC 
TGCGACCCCG CCTTCTACCC GAGCCAAAGA AGCGGCGCCG GCCCACAGCC GCGCCCAGGT 
CGCCCTGCGG ACAAGGACGC GGCCTCGTGC GGGCCAGGGG CCGCTGTGGC GGCGGTGGAG 
CGCGGCGCCG CGGGGCTGCC CAAGGCCAGC CCATTCAGCG TGGAGAGCCT CCTGTCCGAC 
TCGCCGCCGC GCCGGAAAGC CGCTTCCAAC GCCGCCGCCG CCGCCGCCGC GGGGCTGGAC 
TTCGCGCCCG GGCTGCCGTG CGCGCCGCGG ACCCTGATCG GCAAGGGCCA CTTCCTCCTC 
TACCCCATCA CGCAGCCGCT CGGCTTCCTG GTGCCGCAGG CCGCGCTCAA GGGCGGCGCG 
GGCCTGGAGC CGGCGCCCAA GGACGCGCCG CCCGCGCCCG CCGTGCCGCC CGCGCCGCCT 
GCCCAGGCCA GTTTCGGGGC CTTCTCGGGG CCCGGCGGCG CCCCGGACTC GGCCTTCGCG 
CGTCGCAGCC CCGACGCCGT CGCCTCCCCG GGGGCCCCAG CCCCGGCCCC GGCGCCTTTC 
CGGGACCTCG CCTCGGCAGC GGCTACCGAG GGCGGCGGCG GGGACTGCGC GGACGCGGGG 
ACCGCCGGCC CCGCGCCCCC GCCGCCCGCG CCGTCGCCCA GGCCCGGCCC TCGGCCTCCC 
AGCCCCGCCG AGGAGCCGGC CACCTGCGGG GTTCCCGAGC CTGGCGCGGC GGCCGGACCC 
AGCCCGCCGG AGGGCGAGGA GCTGGACATG GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073930.1
CDS	637..2232
Translation	MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPTPLLPAACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEELDMD

Target ORF information:

RefSeq Version	NM_001080461.2
Organism	Homo sapiens(human)
Definition	Homo sapiens UNC homeobox (UNCX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080461.2

ORF Insert Sequence:

ATGATGGACG GCCGCCTCCT GGAACACCCG CATGCCCAGT TCGGGGGCTC GCTGGGCGGC 
GTGGTGGGCT TCCCCTACCC GCTGGGCCAC CACCACGTGT ACGAGCTGGC CGGGCACCAG 
CTGCAGTCGG CCGCCGCCGC CGCCTCGGTG CCCTTCTCCA TCGACGGCCT GCTCGGGGGC 
TCGTGCGCCG CCGCCGCCTC GGTGGTCAAC CCCACGCCGC TGCTGCCAGC CGCCTGCGGG 
GTCGGCGGGG ACGGCCAGCC CTTCAAGCTG TCAGACTCGG GGGACCCGGA CAAGGAGAGC 
CCGGGCTGCA AGCGGCGGCG CACCCGCACC AACTTCACCG GCTGGCAGCT GGAGGAGCTG 
GAGAAGGCGT TCAACGAGAG CCACTATCCC GACGTGTTCA TGCGCGAGGC GCTGGCGCTG 
CGCCTAGACC TGGTCGAGTC CCGAGTTCAG GTCTGGTTCC AAAACCGCCG GGCCAAGTGG 
AGGAAGAAGG AGAACACGAA AAAGGGCCCG GGGCGGCCGG CGCACAACTC GCACCCGACC 
ACGTGCAGCG GCGAGCCCAT GGACCCGGAG GAGATCGCGC GCAAGGAGCT GGAGAAGATG 
GAGAAGAAGA AGCGCAAGCA CGAGAAGAAG CTGCTGAAGA GCCAGGGCCG CCACTTGCAC 
TCGCCCGGCG GCCTGTCCCT GCACAGCGCG CCCAGCTCCG ACAGCGACAG CGGCGGCGGC 
GGCCTGTCTC CGGAGCCGCC CGAGCCGCCG CCGCCCGCCG CCAAGGGCCC CGGAGCGCAC 
GCCTCGGGCG CCGCGGGGAC CGCGCCCGCC CCTCCCGGCG AGCCGCCTGC ACCCGGCACC 
TGCGACCCCG CCTTCTACCC GAGCCAAAGA AGCGGCGCCG GCCCACAGCC GCGCCCAGGT 
CGCCCTGCGG ACAAGGACGC GGCCTCGTGC GGGCCAGGGG CCGCTGTGGC GGCGGTGGAG 
CGCGGCGCCG CGGGGCTGCC CAAGGCCAGC CCATTCAGCG TGGAGAGCCT CCTGTCCGAC 
TCGCCGCCGC GCCGGAAAGC CGCTTCCAAC GCCGCCGCCG CCGCCGCCGC GGGGCTGGAC 
TTCGCGCCCG GGCTGCCGTG CGCGCCGCGG ACCCTGATCG GCAAGGGCCA CTTCCTCCTC 
TACCCCATCA CGCAGCCGCT CGGCTTCCTG GTGCCGCAGG CCGCGCTCAA GGGCGGCGCG 
GGCCTGGAGC CGGCGCCCAA GGACGCGCCG CCCGCGCCCG CCGTGCCGCC CGCGCCGCCT 
GCCCAGGCCA GTTTCGGGGC CTTCTCGGGG CCCGGCGGCG CCCCGGACTC GGCCTTCGCG 
CGTCGCAGCC CCGACGCCGT CGCCTCCCCG GGGGCCCCAG CCCCGGCCCC GGCGCCTTTC 
CGGGACCTCG CCTCGGCAGC GGCTACCGAG GGCGGCGGCG GGGACTGCGC GGACGCGGGG 
ACCGCCGGCC CCGCGCCCCC GCCGCCCGCG CCGTCGCCCA GGCCCGGCCC TCGGCCTCCC 
AGCCCCGCCG AGGAGCCGGC CACCTGCGGG GTTCCCGAGC CTGGCGCGGC GGCCGGACCC 
AGCCCGCCGG AGGGCGAGGA GCTGGACATG GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNCX ( NM_001080461.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073930.1 Homo sapiens UNC homeobox (UNCX), mRNA.

Price & Availability↑

CloneID	OHu29926
Clone ID Related Accession (Same CDS sequence)	NM_001080461.2 , NM_001080461.1 , NM_001080461.3
Accession Version	NM_001080461.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1596bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-11
Organism	Homo sapiens(Human)
Product	homeobox protein unc-4 homolog
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC073094.11. On or before Sep 11, 2007 this sequence version replaced NM_001085389.1, XM_941336.2, XM_294209.7. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: KM587717.1, HY145527.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145774, SAMN03465403 [ECO:0000348] ##Evidence-Data-END##

ATGATGGACG GCCGCCTCCT GGAACACCCG CATGCCCAGT TCGGGGGCTC GCTGGGCGGC 
GTGGTGGGCT TCCCCTACCC GCTGGGCCAC CACCACGTGT ACGAGCTGGC CGGGCACCAG 
CTGCAGTCGG CCGCCGCCGC CGCCTCGGTG CCCTTCTCCA TCGACGGCCT GCTCGGGGGC 
TCGTGCGCCG CCGCCGCCTC GGTGGTCAAC CCCACGCCGC TGCTGCCAGC CGCCTGCGGG 
GTCGGCGGGG ACGGCCAGCC CTTCAAGCTG TCAGACTCGG GGGACCCGGA CAAGGAGAGC 
CCGGGCTGCA AGCGGCGGCG CACCCGCACC AACTTCACCG GCTGGCAGCT GGAGGAGCTG 
GAGAAGGCGT TCAACGAGAG CCACTATCCC GACGTGTTCA TGCGCGAGGC GCTGGCGCTG 
CGCCTAGACC TGGTCGAGTC CCGAGTTCAG GTCTGGTTCC AAAACCGCCG GGCCAAGTGG 
AGGAAGAAGG AGAACACGAA AAAGGGCCCG GGGCGGCCGG CGCACAACTC GCACCCGACC 
ACGTGCAGCG GCGAGCCCAT GGACCCGGAG GAGATCGCGC GCAAGGAGCT GGAGAAGATG 
GAGAAGAAGA AGCGCAAGCA CGAGAAGAAG CTGCTGAAGA GCCAGGGCCG CCACTTGCAC 
TCGCCCGGCG GCCTGTCCCT GCACAGCGCG CCCAGCTCCG ACAGCGACAG CGGCGGCGGC 
GGCCTGTCTC CGGAGCCGCC CGAGCCGCCG CCGCCCGCCG CCAAGGGCCC CGGAGCGCAC 
GCCTCGGGCG CCGCGGGGAC CGCGCCCGCC CCTCCCGGCG AGCCGCCTGC ACCCGGCACC 
TGCGACCCCG CCTTCTACCC GAGCCAAAGA AGCGGCGCCG GCCCACAGCC GCGCCCAGGT 
CGCCCTGCGG ACAAGGACGC GGCCTCGTGC GGGCCAGGGG CCGCTGTGGC GGCGGTGGAG 
CGCGGCGCCG CGGGGCTGCC CAAGGCCAGC CCATTCAGCG TGGAGAGCCT CCTGTCCGAC 
TCGCCGCCGC GCCGGAAAGC CGCTTCCAAC GCCGCCGCCG CCGCCGCCGC GGGGCTGGAC 
TTCGCGCCCG GGCTGCCGTG CGCGCCGCGG ACCCTGATCG GCAAGGGCCA CTTCCTCCTC 
TACCCCATCA CGCAGCCGCT CGGCTTCCTG GTGCCGCAGG CCGCGCTCAA GGGCGGCGCG 
GGCCTGGAGC CGGCGCCCAA GGACGCGCCG CCCGCGCCCG CCGTGCCGCC CGCGCCGCCT 
GCCCAGGCCA GTTTCGGGGC CTTCTCGGGG CCCGGCGGCG CCCCGGACTC GGCCTTCGCG 
CGTCGCAGCC CCGACGCCGT CGCCTCCCCG GGGGCCCCAG CCCCGGCCCC GGCGCCTTTC 
CGGGACCTCG CCTCGGCAGC GGCTACCGAG GGCGGCGGCG GGGACTGCGC GGACGCGGGG 
ACCGCCGGCC CCGCGCCCCC GCCGCCCGCG CCGTCGCCCA GGCCCGGCCC TCGGCCTCCC 
AGCCCCGCCG AGGAGCCGGC CACCTGCGGG GTTCCCGAGC CTGGCGCGGC GGCCGGACCC 
AGCCCGCCGG AGGGCGAGGA GCTGGACATG GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073930.1
CDS	1..1596
Translation	MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPTPLLPAACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEELDMD

Target ORF information:

RefSeq Version	NM_001080461.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens UNC homeobox (UNCX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080461.1

ORF Insert Sequence:

ATGATGGACG GCCGCCTCCT GGAACACCCG CATGCCCAGT TCGGGGGCTC GCTGGGCGGC 
GTGGTGGGCT TCCCCTACCC GCTGGGCCAC CACCACGTGT ACGAGCTGGC CGGGCACCAG 
CTGCAGTCGG CCGCCGCCGC CGCCTCGGTG CCCTTCTCCA TCGACGGCCT GCTCGGGGGC 
TCGTGCGCCG CCGCCGCCTC GGTGGTCAAC CCCACGCCGC TGCTGCCAGC CGCCTGCGGG 
GTCGGCGGGG ACGGCCAGCC CTTCAAGCTG TCAGACTCGG GGGACCCGGA CAAGGAGAGC 
CCGGGCTGCA AGCGGCGGCG CACCCGCACC AACTTCACCG GCTGGCAGCT GGAGGAGCTG 
GAGAAGGCGT TCAACGAGAG CCACTATCCC GACGTGTTCA TGCGCGAGGC GCTGGCGCTG 
CGCCTAGACC TGGTCGAGTC CCGAGTTCAG GTCTGGTTCC AAAACCGCCG GGCCAAGTGG 
AGGAAGAAGG AGAACACGAA AAAGGGCCCG GGGCGGCCGG CGCACAACTC GCACCCGACC 
ACGTGCAGCG GCGAGCCCAT GGACCCGGAG GAGATCGCGC GCAAGGAGCT GGAGAAGATG 
GAGAAGAAGA AGCGCAAGCA CGAGAAGAAG CTGCTGAAGA GCCAGGGCCG CCACTTGCAC 
TCGCCCGGCG GCCTGTCCCT GCACAGCGCG CCCAGCTCCG ACAGCGACAG CGGCGGCGGC 
GGCCTGTCTC CGGAGCCGCC CGAGCCGCCG CCGCCCGCCG CCAAGGGCCC CGGAGCGCAC 
GCCTCGGGCG CCGCGGGGAC CGCGCCCGCC CCTCCCGGCG AGCCGCCTGC ACCCGGCACC 
TGCGACCCCG CCTTCTACCC GAGCCAAAGA AGCGGCGCCG GCCCACAGCC GCGCCCAGGT 
CGCCCTGCGG ACAAGGACGC GGCCTCGTGC GGGCCAGGGG CCGCTGTGGC GGCGGTGGAG 
CGCGGCGCCG CGGGGCTGCC CAAGGCCAGC CCATTCAGCG TGGAGAGCCT CCTGTCCGAC 
TCGCCGCCGC GCCGGAAAGC CGCTTCCAAC GCCGCCGCCG CCGCCGCCGC GGGGCTGGAC 
TTCGCGCCCG GGCTGCCGTG CGCGCCGCGG ACCCTGATCG GCAAGGGCCA CTTCCTCCTC 
TACCCCATCA CGCAGCCGCT CGGCTTCCTG GTGCCGCAGG CCGCGCTCAA GGGCGGCGCG 
GGCCTGGAGC CGGCGCCCAA GGACGCGCCG CCCGCGCCCG CCGTGCCGCC CGCGCCGCCT 
GCCCAGGCCA GTTTCGGGGC CTTCTCGGGG CCCGGCGGCG CCCCGGACTC GGCCTTCGCG 
CGTCGCAGCC CCGACGCCGT CGCCTCCCCG GGGGCCCCAG CCCCGGCCCC GGCGCCTTTC 
CGGGACCTCG CCTCGGCAGC GGCTACCGAG GGCGGCGGCG GGGACTGCGC GGACGCGGGG 
ACCGCCGGCC CCGCGCCCCC GCCGCCCGCG CCGTCGCCCA GGCCCGGCCC TCGGCCTCCC 
AGCCCCGCCG AGGAGCCGGC CACCTGCGGG GTTCCCGAGC CTGGCGCGGC GGCCGGACCC 
AGCCCGCCGG AGGGCGAGGA GCTGGACATG GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNCX ( NM_001080461.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073930.1 Homo sapiens UNC homeobox (UNCX), mRNA.

Price & Availability↑

CloneID	OHu29926
Clone ID Related Accession (Same CDS sequence)	NM_001080461.2 , NM_001080461.1 , NM_001080461.3
Accession Version	NM_001080461.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1596bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	homeobox protein unc-4 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073094.11. On Nov 23, 2018 this sequence version replaced NM_001080461.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: KM587717.1, HY145527.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145774, SAMN03465403 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000316333.9/ ENSP00000314480.8 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGGACG GCCGCCTCCT GGAACACCCG CATGCCCAGT TCGGGGGCTC GCTGGGCGGC 
GTGGTGGGCT TCCCCTACCC GCTGGGCCAC CACCACGTGT ACGAGCTGGC CGGGCACCAG 
CTGCAGTCGG CCGCCGCCGC CGCCTCGGTG CCCTTCTCCA TCGACGGCCT GCTCGGGGGC 
TCGTGCGCCG CCGCCGCCTC GGTGGTCAAC CCCACGCCGC TGCTGCCAGC CGCCTGCGGG 
GTCGGCGGGG ACGGCCAGCC CTTCAAGCTG TCAGACTCGG GGGACCCGGA CAAGGAGAGC 
CCGGGCTGCA AGCGGCGGCG CACCCGCACC AACTTCACCG GCTGGCAGCT GGAGGAGCTG 
GAGAAGGCGT TCAACGAGAG CCACTATCCC GACGTGTTCA TGCGCGAGGC GCTGGCGCTG 
CGCCTAGACC TGGTCGAGTC CCGAGTTCAG GTCTGGTTCC AAAACCGCCG GGCCAAGTGG 
AGGAAGAAGG AGAACACGAA AAAGGGCCCG GGGCGGCCGG CGCACAACTC GCACCCGACC 
ACGTGCAGCG GCGAGCCCAT GGACCCGGAG GAGATCGCGC GCAAGGAGCT GGAGAAGATG 
GAGAAGAAGA AGCGCAAGCA CGAGAAGAAG CTGCTGAAGA GCCAGGGCCG CCACTTGCAC 
TCGCCCGGCG GCCTGTCCCT GCACAGCGCG CCCAGCTCCG ACAGCGACAG CGGCGGCGGC 
GGCCTGTCTC CGGAGCCGCC CGAGCCGCCG CCGCCCGCCG CCAAGGGCCC CGGAGCGCAC 
GCCTCGGGCG CCGCGGGGAC CGCGCCCGCC CCTCCCGGCG AGCCGCCTGC ACCCGGCACC 
TGCGACCCCG CCTTCTACCC GAGCCAAAGA AGCGGCGCCG GCCCACAGCC GCGCCCAGGT 
CGCCCTGCGG ACAAGGACGC GGCCTCGTGC GGGCCAGGGG CCGCTGTGGC GGCGGTGGAG 
CGCGGCGCCG CGGGGCTGCC CAAGGCCAGC CCATTCAGCG TGGAGAGCCT CCTGTCCGAC 
TCGCCGCCGC GCCGGAAAGC CGCTTCCAAC GCCGCCGCCG CCGCCGCCGC GGGGCTGGAC 
TTCGCGCCCG GGCTGCCGTG CGCGCCGCGG ACCCTGATCG GCAAGGGCCA CTTCCTCCTC 
TACCCCATCA CGCAGCCGCT CGGCTTCCTG GTGCCGCAGG CCGCGCTCAA GGGCGGCGCG 
GGCCTGGAGC CGGCGCCCAA GGACGCGCCG CCCGCGCCCG CCGTGCCGCC CGCGCCGCCT 
GCCCAGGCCA GTTTCGGGGC CTTCTCGGGG CCCGGCGGCG CCCCGGACTC GGCCTTCGCG 
CGTCGCAGCC CCGACGCCGT CGCCTCCCCG GGGGCCCCAG CCCCGGCCCC GGCGCCTTTC 
CGGGACCTCG CCTCGGCAGC GGCTACCGAG GGCGGCGGCG GGGACTGCGC GGACGCGGGG 
ACCGCCGGCC CCGCGCCCCC GCCGCCCGCG CCGTCGCCCA GGCCCGGCCC TCGGCCTCCC 
AGCCCCGCCG AGGAGCCGGC CACCTGCGGG GTTCCCGAGC CTGGCGCGGC GGCCGGACCC 
AGCCCGCCGG AGGGCGAGGA GCTGGACATG GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073930.1
CDS	147..1742
Translation	MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPTPLLPAACGVGGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEELDMD

Target ORF information:

RefSeq Version	NM_001080461.3
Organism	Homo sapiens(human)
Definition	Homo sapiens UNC homeobox (UNCX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080461.3

ORF Insert Sequence:

ATGATGGACG GCCGCCTCCT GGAACACCCG CATGCCCAGT TCGGGGGCTC GCTGGGCGGC 
GTGGTGGGCT TCCCCTACCC GCTGGGCCAC CACCACGTGT ACGAGCTGGC CGGGCACCAG 
CTGCAGTCGG CCGCCGCCGC CGCCTCGGTG CCCTTCTCCA TCGACGGCCT GCTCGGGGGC 
TCGTGCGCCG CCGCCGCCTC GGTGGTCAAC CCCACGCCGC TGCTGCCAGC CGCCTGCGGG 
GTCGGCGGGG ACGGCCAGCC CTTCAAGCTG TCAGACTCGG GGGACCCGGA CAAGGAGAGC 
CCGGGCTGCA AGCGGCGGCG CACCCGCACC AACTTCACCG GCTGGCAGCT GGAGGAGCTG 
GAGAAGGCGT TCAACGAGAG CCACTATCCC GACGTGTTCA TGCGCGAGGC GCTGGCGCTG 
CGCCTAGACC TGGTCGAGTC CCGAGTTCAG GTCTGGTTCC AAAACCGCCG GGCCAAGTGG 
AGGAAGAAGG AGAACACGAA AAAGGGCCCG GGGCGGCCGG CGCACAACTC GCACCCGACC 
ACGTGCAGCG GCGAGCCCAT GGACCCGGAG GAGATCGCGC GCAAGGAGCT GGAGAAGATG 
GAGAAGAAGA AGCGCAAGCA CGAGAAGAAG CTGCTGAAGA GCCAGGGCCG CCACTTGCAC 
TCGCCCGGCG GCCTGTCCCT GCACAGCGCG CCCAGCTCCG ACAGCGACAG CGGCGGCGGC 
GGCCTGTCTC CGGAGCCGCC CGAGCCGCCG CCGCCCGCCG CCAAGGGCCC CGGAGCGCAC 
GCCTCGGGCG CCGCGGGGAC CGCGCCCGCC CCTCCCGGCG AGCCGCCTGC ACCCGGCACC 
TGCGACCCCG CCTTCTACCC GAGCCAAAGA AGCGGCGCCG GCCCACAGCC GCGCCCAGGT 
CGCCCTGCGG ACAAGGACGC GGCCTCGTGC GGGCCAGGGG CCGCTGTGGC GGCGGTGGAG 
CGCGGCGCCG CGGGGCTGCC CAAGGCCAGC CCATTCAGCG TGGAGAGCCT CCTGTCCGAC 
TCGCCGCCGC GCCGGAAAGC CGCTTCCAAC GCCGCCGCCG CCGCCGCCGC GGGGCTGGAC 
TTCGCGCCCG GGCTGCCGTG CGCGCCGCGG ACCCTGATCG GCAAGGGCCA CTTCCTCCTC 
TACCCCATCA CGCAGCCGCT CGGCTTCCTG GTGCCGCAGG CCGCGCTCAA GGGCGGCGCG 
GGCCTGGAGC CGGCGCCCAA GGACGCGCCG CCCGCGCCCG CCGTGCCGCC CGCGCCGCCT 
GCCCAGGCCA GTTTCGGGGC CTTCTCGGGG CCCGGCGGCG CCCCGGACTC GGCCTTCGCG 
CGTCGCAGCC CCGACGCCGT CGCCTCCCCG GGGGCCCCAG CCCCGGCCCC GGCGCCTTTC 
CGGGACCTCG CCTCGGCAGC GGCTACCGAG GGCGGCGGCG GGGACTGCGC GGACGCGGGG 
ACCGCCGGCC CCGCGCCCCC GCCGCCCGCG CCGTCGCCCA GGCCCGGCCC TCGGCCTCCC 
AGCCCCGCCG AGGAGCCGGC CACCTGCGGG GTTCCCGAGC CTGGCGCGGC GGCCGGACCC 
AGCCCGCCGG AGGGCGAGGA GCTGGACATG GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells.
Haematologica102(7)1204-1214(2017 Jul)
Daniele G,Simonetti G,Fusilli C,Iacobucci I,Lonoce A,Palazzo A,Lomiento M,Mammoli F,Marsano RM,Marasco E,Mantovani V,Quentmeier H,Drexler HG,Ding J,Palumbo O,Carella M,Nadarajah N,Perricone M,Ottaviani E,Baldazzi C,Testoni N,Papayannidis C,Ferrari S,Mazza T,Martinelli G,Storlazzi CT

Detection of Missing Proteins Using the PRIDE Database as a Source of Mass Spectrometry Evidence.
Journal of proteome research15(11)4101-4115(2016 Nov)
Garin-Muga A,Odriozola L,Mart?nez-Val A,Del Toro N,Mart?nez R,Molina M,Cantero L,Rivera R,Garrido N,Dominguez F,Sanchez Del Pino MM,Vizca?no JA,Corrales FJ,Segura V

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
Nature genetics44(8)904-9(2012 Jul)
Okada Y,Sim X,Go MJ,Wu JY,Gu D,Takeuchi F,Takahashi A,Maeda S,Tsunoda T,Chen P,Lim SC,Wong TY,Liu J,Young TL,Aung T,Seielstad M,Teo YY,Kim YJ,Lee JY,Han BG,Kang D,Chen CH,Tsai FJ,Chang LC,Fann SJ,Mei H,Rao DC,Hixson JE,Chen S,Katsuya T,Isono M,Ogihara T,Chambers JC,Zhang W,Kooner JS,,,Albrecht E,,Yamamoto K,Kubo M,Nakamura Y,Kamatani N,Kato N,He J,Chen YT,Cho YS,Tai ES,Tanaka T

Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men.
Pharmacogenetics and genomics21(12)798-807(2011 Dec)
Irvin MR,Shrestha S,Chen YD,Wiener HW,Haritunians T,Vaughan LK,Tiwari HK,Taylor KD,Scherzer R,Saag MS,Grunfeld C,Rotter JI,Arnett DK

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

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UNCX cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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