NLRP10 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NLRP10
Entrez Gene ID	338322
Full Name	NLR family pyrin domain containing 10
Synonyms	CLR11.1,NALP10,NOD8,PAN5,PYNOD
General protein information	Preferred Names NLR family pyrin domain containing 10 Names NACHT, LRR and PYD domains-containing protein 10 NACHT, leucine rich repeat and PYD containing 10 nucleotide-binding oligomerization domain protein 8 nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.4
Summary	Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008].
Disorder MIM:	609662

mRNA and Protein(s)

mRNA	Protein	Name
XM_011548868.1	XP_011547170.1	NACHT, LRR and PYD domains-containing protein 10 isoform X1
NM_176821.3	NP_789791.1	NACHT, LRR and PYD domains-containing protein 10
XM_011520043.3	XP_011518345.1	NACHT, LRR and PYD domains-containing protein 10 isoform X1
XM_011520043.1	XP_011518345.1	NACHT, LRR and PYD domains-containing protein 10 isoform X1
XM_011546581.1	XP_011544883.1	NACHT, LRR and PYD domains-containing protein 10 isoform X1
XM_011520043.2	XP_011518345.1	NACHT, LRR and PYD domains-containing protein 10 isoform X1
NM_176821.4	NP_789791.1	NACHT, LRR and PYD domains-containing protein 10

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	NLRP10	XP_003313013.1
	NLRP10	XP_001098361.1
Canis lupus familiaris (dog)	NLRP10	XP_854074.1
Mus musculus (house mouse)	Nlrp10	NP_780741.1
Homo sapiens (human)	NLRP10	NP_789791.1
Rattus norvegicus (Norway rat)	Nlrp10	NP_001099761.1

Gene Ontology
Bibliography

Related articles in PubMed

Involvement of NLRP10 in IL-1? induction of oral epithelial cells by periodontal pathogens.
Lee SJ, Choi BK
Innate immunity23(7)569-577(2017 Oct)

Roles of NLRP10 in innate and adaptive immunity.
Damm A, Lautz K, Kufer TA
Microbes and infection15(6-7)516-23(2013 Jun)

Three-dimensional structure of human NLRP10/PYNOD pyrin domain reveals a homotypic interaction site distinct from its mouse homologue.
Su MY, Kuo CI, Chang CF, Chang CI
PloS one8(7)e67843(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Review summarize recent advances of the role of of human and murine NLRP10 in innate and adaptive immune responses. [Review]
Title: Roles of NLRP10 in innate and adaptive immunity.

These data revealed a novel role of NLRP10 in innate immune responses towards bacterial infection and suggest that NLRP10 functions as a scaffold for the formation of the NOD1-Nodosome.
Title: NLRP10 enhances Shigella-induced pro-inflammatory responses.

The results show that either deletion of the p53 binding elements within the PYNOD promoter or treatment with p53 inhibitor could significantly reduce PYNOD promoter activity.
Title: Functional characterization of the p53 binding site in the human PYNOD promoter.

Observational study of gene-disease association. (HuGE Navigator)
Title: The genetics of NOD-like receptors in Crohn's disease.

Transgenic PYNOD colocalizes with apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) and inhibits caspase-1-mediated interleukin (IL)-1beta processing without inhibiting caspase-4-mediated caspase-1 processing.
Title: Anti-inflammatory activity of PYNOD and its mechanism in humans and mice.

The following NLRP10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NLRP10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30514	NM_176821.4 Latest version!	Homo sapiens NLR family pyrin domain containing 10 (NLRP10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu30514	XM_011520043.3 Latest version!	Homo sapiens NLR family pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu30514	XM_011548868.1 Latest version!	Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu30514	XM_011546581.1 Latest version!	Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu30514	XM_011520043.1	Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu30514	XM_011520043.2	Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu30514	NM_176821.3	Homo sapiens NLR family pyrin domain containing 10 (NLRP10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NLRP10 ( NM_176821.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_789791.1 Homo sapiens NLR family pyrin domain containing 10 (NLRP10), mRNA.

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CloneID	OHu30514
Clone ID Related Accession (Same CDS sequence)	XM_011548868.1 , NM_176821.3 , XM_011520043.3 , XM_011520043.1 , XM_011546581.1 , XM_011520043.2 , NM_176821.4
Accession Version	NM_176821.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-29
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 10
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY489192.1. This sequence is a reference standard in the RefSeqGene project. On Oct 27, 2005 this sequence version replaced NM_176821.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY489192.1, BC104957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END##

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_789791.1
CDS	18..1985
Translation	MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI

Target ORF information:

RefSeq Version	NM_176821.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 10 (NLRP10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176821.3

ORF Insert Sequence:

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP10 ( NM_176821.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_789791.1 Homo sapiens NLR family pyrin domain containing 10 (NLRP10), mRNA.

Price & Availability↑

CloneID	OHu30514
Clone ID Related Accession (Same CDS sequence)	XM_011548868.1 , NM_176821.3 , XM_011520043.3 , XM_011520043.1 , XM_011546581.1 , XM_011520043.2 , NM_176821.4
Accession Version	NM_176821.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 10
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC044810.7 and AY489192.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_176821.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC104957.1, AY489192.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_789791.1
CDS	180..2147
Translation	MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI

Target ORF information:

RefSeq Version	NM_176821.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 10 (NLRP10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176821.4

ORF Insert Sequence:

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP10 ( XM_011548868.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011547170.1 Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu30514
Clone ID Related Accession (Same CDS sequence)	XM_011548868.1 , NM_176821.3 , XM_011520043.3 , XM_011520043.1 , XM_011546581.1 , XM_011520043.2 , NM_176821.4
Accession Version	XM_011548868.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	NACHT, LRR and PYD domains-containing protein 10 isoform X1
Comment

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011547170.1

Translation

MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI

Target ORF information:

RefSeq Version	XM_011548868.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011548868.1

ORF Insert Sequence:

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP10 ( XM_011520043.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518345.1 Homo sapiens NLR family pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu30514
Clone ID Related Accession (Same CDS sequence)	XM_011548868.1 , NM_176821.3 , XM_011520043.3 , XM_011520043.1 , XM_011546581.1 , XM_011520043.2 , NM_176821.4
Accession Version	XM_011520043.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011520043.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518345.1
CDS	228..2195
Translation	MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI

Target ORF information:

RefSeq Version	XM_011520043.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520043.3

ORF Insert Sequence:

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP10 ( XM_011520043.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518345.1 Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu30514
Clone ID Related Accession (Same CDS sequence)	XM_011548868.1 , NM_176821.3 , XM_011520043.3 , XM_011520043.1 , XM_011546581.1 , XM_011520043.2 , NM_176821.4
Accession Version	XM_011520043.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	NACHT, LRR and PYD domains-containing protein 10 isoform X1
Comment

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011518345.1

Translation

MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI

Target ORF information:

RefSeq Version	XM_011520043.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520043.1

ORF Insert Sequence:

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP10 ( XM_011546581.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544883.1 Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

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CloneID	OHu30514
Clone ID Related Accession (Same CDS sequence)	XM_011548868.1 , NM_176821.3 , XM_011520043.3 , XM_011520043.1 , XM_011546581.1 , XM_011520043.2 , NM_176821.4
Accession Version	XM_011546581.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	NACHT, LRR and PYD domains-containing protein 10 isoform X1
Comment

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011544883.1

Translation

MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI

Target ORF information:

RefSeq Version	XM_011546581.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011546581.1

ORF Insert Sequence:

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP10 ( XM_011520043.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011518345.1 Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu30514
Clone ID Related Accession (Same CDS sequence)	XM_011548868.1 , NM_176821.3 , XM_011520043.3 , XM_011520043.1 , XM_011546581.1 , XM_011520043.2 , NM_176821.4
Accession Version	XM_011520043.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011520043.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011518345.1
CDS	228..2195
Translation	MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI

Target ORF information:

RefSeq Version	XM_011520043.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family, pyrin domain containing 10 (NLRP10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520043.2

ORF Insert Sequence:

ATGGCCATGG CCAAGGCCAG AAAGCCCCGG GAGGCATTGC TCTGGGCCTT GAGTGACCTT 
GAGGAGAACG ATTTCAAGAA GTTAAAGTTC TACTTACGGG ATATGACCCT GTCTGAGGGC 
CAGCCCCCAC TGGCCAGAGG GGAGTTGGAG GGCCTGATTC CGGTGGACCT GGCAGAATTA 
CTGATTTCAA AGTATGGAGA AAAGGAGGCT GTGAAAGTTG TCCTCAAGGG CTTGAAGGTC 
ATGAACCTGT TGGAACTTGT GGACCAGCTC AGCCATATTT GTCTGCATGA TTACAGAGAA 
GTATACCGAG AGCATGTGCG CTGCCTAGAG GAATGGCAGG AAGCAGGAGT CAATGGCAGA 
TACAACCAGG TGCTCCTGGT GGCCAAGCCC AGCTCAGAGA GCCCAGAATC ACTTGCCTGC 
CCCTTCCCGG AGCAGGAGCT GGAGTCTGTC ACGGTGGAGG CTCTATTTGA TTCAGGGGAA 
AAGCCCTCAC TGGCCCCATC CTTAGTTGTG CTACAGGGGT CGGCTGGCAC TGGAAAGACA 
ACTCTCGCCA GAAAAATGGT GTTGGACTGG GCCACCGGTA CTCTGTACCC AGGCCGGTTT 
GATTATGTCT TTTATGTAAG CTGCAAAGAA GTGGTCCTGC TGCTGGAGAG CAAACTGGAG 
CAGCTCCTTT TCTGGTGCTG CGGGGACAAT CAAGCCCCTG TCACAGAGAT TCTGAGGCAG 
CCAGAGCGGC TCCTGTTCAT CCTGGATGGC TTTGATGAGC TGCAGAGGCC CTTTGAAGAA 
AAGTTGAAGA AGAGGGGTTT GAGTCCCAAG GAGAGCCTGC TGCACCTTCT AATTAGGAGA 
CATACACTCC CCACGTGCTC CCTTCTCATC ACCACCCGGC CCCTGGCTTT GAGGAATCTG 
GAGCCCTTGC TGAAACAAGC ACGTCATGTC CATATCCTAG GCTTCTCTGA GGAGGAGAGG 
GCGAGGTACT TCAGCTCCTA TTTCACGGAT GAGAAGCAAG CTGACCGTGC CTTCGACATT 
GTACAGAAAA ATGACATTCT CTACAAAGCG TGTCAGGTTC CAGGCATTTG CTGGGTGGTC 
TGCTCCTGGC TGCAGGGGCA GATGGAGAGA GGCAAAGTTG TCTTAGAGAC ACCTAGAAAC 
AGCACTGACA TCTTCATGGC TTACGTCTCC ACCTTTCTGC CGCCCGATGA TGATGGGGGC 
TGCTCCGAGC TTTCCCGGCA CAGGGTCCTG AGGAGTCTGT GCTCCCTAGC AGCTGAAGGG 
ATTCAGCACC AGAGGTTCCT ATTTGAAGAA GCTGAGCTCA GGAAACATAA TTTAGATGGC 
CCCAGGCTTG CCGCTTTCCT GAGTAGTAAC GACTACCAAT TGGGACTTGC CATCAAGAAG 
TTCTACAGCT TCCGCCACAT CAGCTTCCAG GACTTTTTTC ATGCCATGTC TTACCTGGTG 
AAAGAGGACC AAAGCCGGCT GGGGAAGGAG TCCCGCAGAG AAGTGCAAAG GCTGCTGGAG 
GTAAAGGAGC AGGAAGGGAA TGATGAGATG ACCCTCACTA TGCAGTTTTT ACTGGACATC 
TCGAAAAAAG ACAGCTTCTC GAACTTGGAG CTCAAGTTCT GCTTCAGAAT TTCTCCCTGT 
TTAGCGCAGG ATCTGAAGCA TTTTAAAGAA CAGATGGAAT CTATGAAGCA CAACAGGACC 
TGGGATTTGG AATTCTCCCT GTATGAAGCT AAAATAAAGA ATCTGGTAAA AGGTATTCAG 
ATGAACAATG TATCATTCAA GATAAAACAT TCAAATGAAA AGAAATCACA GAGCCAGAAT 
TTATTTTCTG TCAAAAGCAG CTTGAGTCAT GGACCTAAGG AGGAGCAAAA ATGTCCTTCT 
GTCCATGGAC AGAAGGAGGG CAAAGATAAT ATAGCAGGAA CACAAAAGGA AGCTTCTACT 
GGAAAAGGCA GAGGGACAGA GGAAACACCA AAAAATACTT ACATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Involvement of NLRP10 in IL-1? induction of oral epithelial cells by periodontal pathogens.
Innate immunity23(7)569-577(2017 Oct)
Lee SJ,Choi BK

Roles of NLRP10 in innate and adaptive immunity.
Microbes and infection15(6-7)516-23(2013 Jun)
Damm A,Lautz K,Kufer TA

Three-dimensional structure of human NLRP10/PYNOD pyrin domain reveals a homotypic interaction site distinct from its mouse homologue.
PloS one8(7)e67843(2013)
Su MY,Kuo CI,Chang CF,Chang CI

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NLRP10 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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