HSD11B2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HSD11B2
Entrez Gene ID	3291
Full Name	hydroxysteroid 11-beta dehydrogenase 2
Synonyms	AME,AME1,HSD11K,HSD2,SDR9C3
General protein information	Preferred Names hydroxysteroid 11-beta dehydrogenase 2 Names corticosteroid 11-beta-dehydrogenase isozyme 2 -HSD11 type II 11-DH2 11-HSD type II 11-beta-HSD type II 11-beta-HSD2 11-beta-hydroxysteroid dehydrogenase type 2 11-beta-hydroxysteroid dehydrogenase type II NAD-dependent 11-beta-hydroxysteroid dehydrogenase short chain dehydrogenase/reductase family 9C member 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q22.1
Summary	There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010].
Disorder MIM:	614232
Disorder Html:	Apparent mineralocorticoid excess, 218030 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000196.4	NP_000187.3	corticosteroid 11-beta-dehydrogenase isozyme 2
NM_000196.3	NP_000187.3	corticosteroid 11-beta-dehydrogenase isozyme 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Hsd11b2	NP_032315.2
Danio rerio (zebrafish)	hsd11b2	NP_997885.2
Homo sapiens (human)	HSD11B2	NP_000187.3
Pan troglodytes (chimpanzee)	HSD11B2	XP_523393.2
	HSD11B2	XP_001088119.2
Gallus gallus (chicken)	LOC100858361	XP_003641938.1
Gallus gallus (chicken)	HSD11B2	XP_003643226.1
Xenopus tropicalis (tropical clawed frog)	hsd11b2	XP_002937366.1
Bos taurus (cattle)	HSD11B2	NP_777067.1
Rattus norvegicus (Norway rat)	Hsd11b2	NP_058777.1
Canis lupus familiaris (dog)	HSD11B2	XP_005620879.1

Gene Ontology
Bibliography

Related articles in PubMed

Clinical, genetic, and structural basis of apparent mineralocorticoid excess due to 11?-hydroxysteroid dehydrogenase type 2 deficiency.
Yau M, Haider S, Khattab A, Ling C, Mathew M, Zaidi S, Bloch M, Patel M, Ewert S, Abdullah W, Toygar A, Mudryi V, Al Badi M, Alzubdi M, Wilson RC, Al Azkawi HS, Ozdemir HN, Abu-Amer W, Hertecant J, Razzaghy-Azar M, Funder JW, Al Senani A, Sun L, Kim SM, Yuen T, Zaidi M, New MI
Proceedings of the National Academy of Sciences of the United States of America114(52)E11248-E11256(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SUMOylation of 11beta-HSD2 at residue K266 modulates cortisol-mediated MR nuclear translocation independently of effects on transactivation.
Title: 11?-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation.

The data demonstrate for the first time that 11b- HSD2 plays a key role in the pathophysiology of malignant epidermal cells.
Title: Characterisation of the cancer-associated glucocorticoid system: key role of 11?-hydroxysteroid dehydrogenase type 2.

enhancer of zeste homolog 2 (EZH2) accounts for the silence of 11beta-HSD2 expression via trimethylation of histone H3 lysine 27 at the promoter of the 11beta-HSD2 gene.
Title: A repressive role of enhancer of zeste homolog 2 in 11?-hydroxysteroid dehydrogenase type 2 expression in the human placenta.

Rac1 GTPase regulates 11beta-HSD2 expression, mineralocorticoid receptor activation, and mineralocorticoid receptor-mediated pro-fibrotic signaling.
Title: Rac1 GTPase regulates 11? hydroxysteroid dehydrogenase type 2 and fibrotic remodeling.

11beta-HSD2 activity is not reduced in patients with drug resistant hypertension, suggesting that variation in the conversion of cortisol to cortisone does not contribute to development of antihypertensive treatment resistance.
Title: 11-Beta Dehydrogenase Type 2 Activity Is Not Reduced in Treatment Resistant Hypertension.

The following HSD11B2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSD11B2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20200	NM_000196.4 Latest version!	Homo sapiens hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu20200	NM_000196.3	Homo sapiens hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HSD11B2 ( NM_000196.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000187.3 Homo sapiens hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2), mRNA.

Price & Availability↑

CloneID	OHu20200
Clone ID Related Accession (Same CDS sequence)	NM_000196.4 , NM_000196.3
Accession Version	NM_000196.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	corticosteroid 11-beta-dehydrogenase isozyme 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009061.10, BC036780.1 and BC064536.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000196.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036780.1, U26726.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000326152.6/ ENSP00000316786.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCGCT GGCCTTGGCC GTCGGGCGGC GCCTGGCTGC TCGTGGCTGC CCGCGCGCTG 
CTGCAGCTGC TGCGCTCAGA CCTGCGTCTG GGCCGCCCGC TGCTGGCGGC GCTGGCGCTG 
CTGGCCGCGC TCGACTGGCT GTGCCAGCGC CTGCTGCCCC CGCCGGCCGC ACTCGCCGTG 
CTGGCCGCCG CCGGCTGGAT CGCGTTGTCC CGCCTGGCGC GCCCGCAGCG CCTGCCGGTG 
GCCACTCGCG CGGTGCTCAT CACCGGCTGT GACTCTGGTT TTGGCAAGGA GACGGCCAAG 
AAACTGGACT CCATGGGCTT CACGGTGCTG GCCACCGTAT TGGAGTTGAA CAGCCCCGGT 
GCCATCGAGC TGCGTACCTG CTGCTCCCCT CGCCTAAGGC TGCTGCAGAT GGACCTGACC 
AAACCAGGAG ACATTAGCCG CGTGCTAGAG TTCACCAAGG CCCACACCAC CAGCACCGGC 
CTGTGGGGCC TCGTCAACAA CGCAGGCCAC AATGAAGTAG TTGCTGATGC GGAGCTGTCT 
CCAGTGGCCA CTTTCCGTAG CTGCATGGAG GTGAATTTCT TTGGCGCGCT CGAGCTGACC 
AAGGGCCTCC TGCCCCTGCT GCGCAGCTCA AGGGGCCGCA TCGTGACTGT GGGGAGCCCA 
GCGGGGGACA TGCCATATCC GTGCTTGGGG GCCTATGGAA CCTCCAAAGC GGCCGTGGCG 
CTACTCATGG ACACATTCAG CTGTGAACTC CTTCCCTGGG GGGTCAAGGT CAGCATCATC 
CAGCCTGGCT GCTTCAAGAC AGAGTCAGTG AGAAACGTGG GTCAGTGGGA AAAGCGCAAG 
CAATTGCTGC TGGCCAACCT GCCTCAAGAG CTGCTGCAGG CCTACGGCAA GGACTACATC 
GAGCACTTGC ATGGGCAGTT CCTGCACTCG CTACGCCTGG CCATGTCCGA CCTCACCCCA 
GTTGTAGATG CCATCACAGA TGCGCTGCTG GCAGCTCGGC CCCGCCGCCG CTATTACCCC 
GGCCAGGGCC TGGGGCTCAT GTACTTCATC CACTACTACC TGCCTGAAGG CCTGCGGCGC 
CGCTTCCTGC AGGCCTTCTT CATCAGTCAC TGTCTGCCTC GAGCACTGCA GCCTGGCCAG 
CCTGGCACTA CCCCACCACA GGACGCAGCC CAGGACCCAA ACCTGAGCCC CGGCCCTTCC 
CCAGCAGTGG CTCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000187.3
CDS	129..1346
Translation	MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALAVLAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLPQELLQAYGKDYIEHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYPGQGLGLMYFIHYYLPEGLRRRFLQAFFISHCLPRALQPGQPGTTPPQDAAQDPNLSPGPSPAVAR

Target ORF information:

RefSeq Version	NM_000196.4
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000196.4

ORF Insert Sequence:

ATGGAGCGCT GGCCTTGGCC GTCGGGCGGC GCCTGGCTGC TCGTGGCTGC CCGCGCGCTG 
CTGCAGCTGC TGCGCTCAGA CCTGCGTCTG GGCCGCCCGC TGCTGGCGGC GCTGGCGCTG 
CTGGCCGCGC TCGACTGGCT GTGCCAGCGC CTGCTGCCCC CGCCGGCCGC ACTCGCCGTG 
CTGGCCGCCG CCGGCTGGAT CGCGTTGTCC CGCCTGGCGC GCCCGCAGCG CCTGCCGGTG 
GCCACTCGCG CGGTGCTCAT CACCGGCTGT GACTCTGGTT TTGGCAAGGA GACGGCCAAG 
AAACTGGACT CCATGGGCTT CACGGTGCTG GCCACCGTAT TGGAGTTGAA CAGCCCCGGT 
GCCATCGAGC TGCGTACCTG CTGCTCCCCT CGCCTAAGGC TGCTGCAGAT GGACCTGACC 
AAACCAGGAG ACATTAGCCG CGTGCTAGAG TTCACCAAGG CCCACACCAC CAGCACCGGC 
CTGTGGGGCC TCGTCAACAA CGCAGGCCAC AATGAAGTAG TTGCTGATGC GGAGCTGTCT 
CCAGTGGCCA CTTTCCGTAG CTGCATGGAG GTGAATTTCT TTGGCGCGCT CGAGCTGACC 
AAGGGCCTCC TGCCCCTGCT GCGCAGCTCA AGGGGCCGCA TCGTGACTGT GGGGAGCCCA 
GCGGGGGACA TGCCATATCC GTGCTTGGGG GCCTATGGAA CCTCCAAAGC GGCCGTGGCG 
CTACTCATGG ACACATTCAG CTGTGAACTC CTTCCCTGGG GGGTCAAGGT CAGCATCATC 
CAGCCTGGCT GCTTCAAGAC AGAGTCAGTG AGAAACGTGG GTCAGTGGGA AAAGCGCAAG 
CAATTGCTGC TGGCCAACCT GCCTCAAGAG CTGCTGCAGG CCTACGGCAA GGACTACATC 
GAGCACTTGC ATGGGCAGTT CCTGCACTCG CTACGCCTGG CCATGTCCGA CCTCACCCCA 
GTTGTAGATG CCATCACAGA TGCGCTGCTG GCAGCTCGGC CCCGCCGCCG CTATTACCCC 
GGCCAGGGCC TGGGGCTCAT GTACTTCATC CACTACTACC TGCCTGAAGG CCTGCGGCGC 
CGCTTCCTGC AGGCCTTCTT CATCAGTCAC TGTCTGCCTC GAGCACTGCA GCCTGGCCAG 
CCTGGCACTA CCCCACCACA GGACGCAGCC CAGGACCCAA ACCTGAGCCC CGGCCCTTCC 
CCAGCAGTGG CTCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD11B2 ( NM_000196.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000187.3 Homo sapiens hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2), mRNA.

Price & Availability↑

CloneID	OHu20200
Clone ID Related Accession (Same CDS sequence)	NM_000196.4 , NM_000196.3
Accession Version	NM_000196.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	corticosteroid 11-beta-dehydrogenase isozyme 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036780.1 and BC064536.1. This sequence is a reference standard in the RefSeqGene project. On Dec 14, 2006 this sequence version replaced NM_000196.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036780.1, U26726.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGCT GGCCTTGGCC GTCGGGCGGC GCCTGGCTGC TCGTGGCTGC CCGCGCGCTG 
CTGCAGCTGC TGCGCTCAGA CCTGCGTCTG GGCCGCCCGC TGCTGGCGGC GCTGGCGCTG 
CTGGCCGCGC TCGACTGGCT GTGCCAGCGC CTGCTGCCCC CGCCGGCCGC ACTCGCCGTG 
CTGGCCGCCG CCGGCTGGAT CGCGTTGTCC CGCCTGGCGC GCCCGCAGCG CCTGCCGGTG 
GCCACTCGCG CGGTGCTCAT CACCGGCTGT GACTCTGGTT TTGGCAAGGA GACGGCCAAG 
AAACTGGACT CCATGGGCTT CACGGTGCTG GCCACCGTAT TGGAGTTGAA CAGCCCCGGT 
GCCATCGAGC TGCGTACCTG CTGCTCCCCT CGCCTAAGGC TGCTGCAGAT GGACCTGACC 
AAACCAGGAG ACATTAGCCG CGTGCTAGAG TTCACCAAGG CCCACACCAC CAGCACCGGC 
CTGTGGGGCC TCGTCAACAA CGCAGGCCAC AATGAAGTAG TTGCTGATGC GGAGCTGTCT 
CCAGTGGCCA CTTTCCGTAG CTGCATGGAG GTGAATTTCT TTGGCGCGCT CGAGCTGACC 
AAGGGCCTCC TGCCCCTGCT GCGCAGCTCA AGGGGCCGCA TCGTGACTGT GGGGAGCCCA 
GCGGGGGACA TGCCATATCC GTGCTTGGGG GCCTATGGAA CCTCCAAAGC GGCCGTGGCG 
CTACTCATGG ACACATTCAG CTGTGAACTC CTTCCCTGGG GGGTCAAGGT CAGCATCATC 
CAGCCTGGCT GCTTCAAGAC AGAGTCAGTG AGAAACGTGG GTCAGTGGGA AAAGCGCAAG 
CAATTGCTGC TGGCCAACCT GCCTCAAGAG CTGCTGCAGG CCTACGGCAA GGACTACATC 
GAGCACTTGC ATGGGCAGTT CCTGCACTCG CTACGCCTGG CCATGTCCGA CCTCACCCCA 
GTTGTAGATG CCATCACAGA TGCGCTGCTG GCAGCTCGGC CCCGCCGCCG CTATTACCCC 
GGCCAGGGCC TGGGGCTCAT GTACTTCATC CACTACTACC TGCCTGAAGG CCTGCGGCGC 
CGCTTCCTGC AGGCCTTCTT CATCAGTCAC TGTCTGCCTC GAGCACTGCA GCCTGGCCAG 
CCTGGCACTA CCCCACCACA GGACGCAGCC CAGGACCCAA ACCTGAGCCC CGGCCCTTCC 
CCAGCAGTGG CTCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000187.3
CDS	117..1334
Translation	MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALAVLAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLPQELLQAYGKDYIEHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYPGQGLGLMYFIHYYLPEGLRRRFLQAFFISHCLPRALQPGQPGTTPPQDAAQDPNLSPGPSPAVAR

Target ORF information:

RefSeq Version	NM_000196.3
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000196.3

ORF Insert Sequence:

ATGGAGCGCT GGCCTTGGCC GTCGGGCGGC GCCTGGCTGC TCGTGGCTGC CCGCGCGCTG 
CTGCAGCTGC TGCGCTCAGA CCTGCGTCTG GGCCGCCCGC TGCTGGCGGC GCTGGCGCTG 
CTGGCCGCGC TCGACTGGCT GTGCCAGCGC CTGCTGCCCC CGCCGGCCGC ACTCGCCGTG 
CTGGCCGCCG CCGGCTGGAT CGCGTTGTCC CGCCTGGCGC GCCCGCAGCG CCTGCCGGTG 
GCCACTCGCG CGGTGCTCAT CACCGGCTGT GACTCTGGTT TTGGCAAGGA GACGGCCAAG 
AAACTGGACT CCATGGGCTT CACGGTGCTG GCCACCGTAT TGGAGTTGAA CAGCCCCGGT 
GCCATCGAGC TGCGTACCTG CTGCTCCCCT CGCCTAAGGC TGCTGCAGAT GGACCTGACC 
AAACCAGGAG ACATTAGCCG CGTGCTAGAG TTCACCAAGG CCCACACCAC CAGCACCGGC 
CTGTGGGGCC TCGTCAACAA CGCAGGCCAC AATGAAGTAG TTGCTGATGC GGAGCTGTCT 
CCAGTGGCCA CTTTCCGTAG CTGCATGGAG GTGAATTTCT TTGGCGCGCT CGAGCTGACC 
AAGGGCCTCC TGCCCCTGCT GCGCAGCTCA AGGGGCCGCA TCGTGACTGT GGGGAGCCCA 
GCGGGGGACA TGCCATATCC GTGCTTGGGG GCCTATGGAA CCTCCAAAGC GGCCGTGGCG 
CTACTCATGG ACACATTCAG CTGTGAACTC CTTCCCTGGG GGGTCAAGGT CAGCATCATC 
CAGCCTGGCT GCTTCAAGAC AGAGTCAGTG AGAAACGTGG GTCAGTGGGA AAAGCGCAAG 
CAATTGCTGC TGGCCAACCT GCCTCAAGAG CTGCTGCAGG CCTACGGCAA GGACTACATC 
GAGCACTTGC ATGGGCAGTT CCTGCACTCG CTACGCCTGG CCATGTCCGA CCTCACCCCA 
GTTGTAGATG CCATCACAGA TGCGCTGCTG GCAGCTCGGC CCCGCCGCCG CTATTACCCC 
GGCCAGGGCC TGGGGCTCAT GTACTTCATC CACTACTACC TGCCTGAAGG CCTGCGGCGC 
CGCTTCCTGC AGGCCTTCTT CATCAGTCAC TGTCTGCCTC GAGCACTGCA GCCTGGCCAG 
CCTGGCACTA CCCCACCACA GGACGCAGCC CAGGACCCAA ACCTGAGCCC CGGCCCTTCC 
CCAGCAGTGG CTCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinical, genetic, and structural basis of apparent mineralocorticoid excess due to 11?-hydroxysteroid dehydrogenase type 2 deficiency.
Proceedings of the National Academy of Sciences of the United States of America114(52)E11248-E11256(2017 Dec)
Yau M,Haider S,Khattab A,Ling C,Mathew M,Zaidi S,Bloch M,Patel M,Ewert S,Abdullah W,Toygar A,Mudryi V,Al Badi M,Alzubdi M,Wilson RC,Al Azkawi HS,Ozdemir HN,Abu-Amer W,Hertecant J,Razzaghy-Azar M,Funder JW,Al Senani A,Sun L,Kim SM,Yuen T,Zaidi M,New MI

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

HSD11B2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報