APEX1 gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_005267581.3	XP_005267638.1	DNA-(apurinic or apyrimidinic site) lyase isoform X1
NM_001641.3	NP_001632.2	DNA-(apurinic or apyrimidinic site) lyase
NM_080649.3	NP_542380.1	DNA-(apurinic or apyrimidinic site) lyase
NM_001244249.2	NP_001231178.1	DNA-(apurinic or apyrimidinic site) lyase
NM_080648.2	NP_542379.1	DNA-(apurinic or apyrimidinic site) lyase
NM_080648.3	NP_542379.1	DNA-(apurinic or apyrimidinic site) lyase
NM_080649.2	NP_542380.1	DNA-(apurinic or apyrimidinic site) lyase
NM_001244249.1	NP_001231178.1	DNA-(apurinic or apyrimidinic site) lyase
NM_001641.4	NP_001632.2	DNA-(apurinic or apyrimidinic site) lyase

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22005	NM_080649.3 Latest version!	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22005	NM_080648.3 Latest version!	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22005	NM_001641.4 Latest version!	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22005	NM_001244249.2 Latest version!	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22005	XM_005267581.3 Latest version!	Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu22005	NM_080648.2	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22005	NM_080649.2	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22005	NM_001244249.1	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22005	NM_001641.3	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

APEX1 ( NM_001641.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001632.2 Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	NM_001641.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	DNA-(apurinic or apyrimidinic site) lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL355075.6, AK291100.1 and AI554786.1. This sequence is a reference standard in the RefSeqGene project. On Sep 14, 2011 this sequence version replaced NM_001641.2. Transcript Variant: This variant (1) contains the full-length first exon and is the longest transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.714779.1, SRR1163655.441507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001632.2
CDS	333..1289
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	NM_001641.3
Organism	Homo sapiens(human)
Definition	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001641.3

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APEX1 ( NM_080649.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_542380.1 Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	NM_080649.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	DNA-(apurinic or apyrimidinic site) lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC095428.1. On May 31, 2019 this sequence version replaced NM_080649.2. Transcript Variant: This variant (3) uses a donor splice site for exon 1 downstream of that used by variant 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.533528.1, BC095428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542380.1
CDS	182..1138
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	NM_080649.3
Organism	Homo sapiens(human)
Definition	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080649.3

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APEX1 ( NM_001244249.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231178.1 Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	NM_001244249.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	DNA-(apurinic or apyrimidinic site) lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB139337.1, AK291100.1 and AI554786.1. On May 31, 2019 this sequence version replaced NM_001244249.1. Transcript Variant: This variant (4) uses a donor splice site for exon 1 downstream of that used by variant 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.189097.1, SRR5189658.144409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231178.1
CDS	233..1189
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	NM_001244249.2
Organism	Homo sapiens(human)
Definition	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244249.2

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APEX1 ( NM_080648.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_542379.1 Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	NM_080648.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	DNA-(apurinic or apyrimidinic site) lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL355075.6, BC004979.1 and AI554786.1. On Sep 14, 2011 this sequence version replaced NM_080648.1. Transcript Variant: This variant (2) uses a different donor splice site for exon 1 when compared to variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.221413.1, ERR279860.167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542379.1
CDS	267..1223
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	NM_080648.2
Organism	Homo sapiens(human)
Definition	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080648.2

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APEX1 ( NM_080648.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_542379.1 Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	NM_080648.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	DNA-(apurinic or apyrimidinic site) lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL355075.6 and BC004979.1. On May 31, 2019 this sequence version replaced NM_080648.2. Transcript Variant: This variant (2) uses a different donor splice site for exon 1 when compared to variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.126332.1, BC004979.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542379.1
CDS	172..1128
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	NM_080648.3
Organism	Homo sapiens(human)
Definition	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080648.3

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APEX1 ( NM_080649.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_542380.1 Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	NM_080649.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	DNA-(apurinic or apyrimidinic site) lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL355075.6, BC095428.1 and AI554786.1. On Sep 14, 2011 this sequence version replaced NM_080649.1. Transcript Variant: This variant (3) uses a donor splice site for exon 1 downstream of that used by variant 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK098588.1, BC095428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542380.1
CDS	277..1233
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	NM_080649.2
Organism	Homo sapiens(human)
Definition	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080649.2

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APEX1 ( NM_001244249.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231178.1 Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	NM_001244249.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	DNA-(apurinic or apyrimidinic site) lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL355075.6, CB139337.1, AK291100.1 and AI554786.1. Transcript Variant: This variant (4) uses a donor splice site for exon 1 downstream of that used by variant 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.515815.1, SRR1163658.10549.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231178.1
CDS	328..1284
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	NM_001244249.1
Organism	Homo sapiens(human)
Definition	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244249.1

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APEX1 ( NM_001641.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001632.2 Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	NM_001641.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	DNA-(apurinic or apyrimidinic site) lyase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK291100.1 and AI554786.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001641.3. Transcript Variant: This variant (1) contains the full-length first exon and is the longest transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.441507.1, SRR3476690.1071603.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology MANE Ensembl match :: ENST00000216714.8/ ENSP00000216714.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001632.2
CDS	238..1194
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	NM_001641.4
Organism	Homo sapiens(human)
Definition	Homo sapiens apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001641.4

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APEX1 ( XM_005267581.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005267638.1 Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant X1, mRNA.

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CloneID	OHu22005
Clone ID Related Accession (Same CDS sequence)	XM_005267581.3 , NM_001641.3 , NM_080649.3 , NM_001244249.2 , NM_080648.2 , NM_080648.3 , NM_080649.2 , NM_001244249.1 , NM_001641.4
Accession Version	XM_005267581.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	DNA-(apurinic or apyrimidinic site) lyase isoform X1
Comment

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005267638.1
Translation	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

Target ORF information:

RefSeq Version	XM_005267581.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267581.3

ORF Insert Sequence:

ATGCCGAAGC GTGGGAAAAA GGGAGCGGTG GCGGAAGACG GGGATGAGCT CAGGACAGAG 
CCAGAGGCCA AGAAGAGTAA GACGGCCGCA AAGAAAAATG ACAAAGAGGC AGCAGGAGAG 
GGCCCAGCCC TGTATGAGGA CCCCCCAGAT CAGAAAACCT CACCCAGTGG CAAACCTGCC 
ACACTCAAGA TCTGCTCTTG GAATGTGGAT GGGCTTCGAG CCTGGATTAA GAAGAAAGGA 
TTAGATTGGG TAAAGGAAGA AGCCCCAGAT ATACTGTGCC TTCAAGAGAC CAAATGTTCA 
GAGAACAAAC TACCAGCTGA ACTTCAGGAG CTGCCTGGAC TCTCTCATCA ATACTGGTCA 
GCTCCTTCGG ACAAGGAAGG GTACAGTGGC GTGGGCCTGC TTTCCCGCCA GTGCCCACTC 
AAAGTTTCTT ACGGCATAGG CGATGAGGAG CATGATCAGG AAGGCCGGGT GATTGTGGCT 
GAATTTGACT CGTTTGTGCT GGTAACAGCA TATGTACCTA ATGCAGGCCG AGGTCTGGTA 
CGACTGGAGT ACCGGCAGCG CTGGGATGAA GCCTTTCGCA AGTTCCTGAA GGGCCTGGCT 
TCCCGAAAGC CCCTTGTGCT GTGTGGAGAC CTCAATGTGG CACATGAAGA AATTGACCTT 
CGCAACCCCA AGGGGAACAA AAAGAATGCT GGCTTCACGC CACAAGAGCG CCAAGGCTTC 
GGGGAATTAC TGCAGGCTGT GCCACTGGCT GACAGCTTTA GGCACCTCTA CCCCAACACA 
CCCTATGCCT ACACCTTTTG GACTTATATG ATGAATGCTC GATCCAAGAA TGTTGGTTGG 
CGCCTTGATT ACTTTTTGTT GTCCCACTCT CTGTTACCTG CATTGTGTGA CAGCAAGATC 
CGTTCCAAGG CCCTCGGCAG TGATCACTGT CCTATCACCC TATACCTAGC ACTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	APEX1
Entrez Gene ID	328
Full Name	apurinic/apyrimidinic endodeoxyribonuclease 1
Synonyms	APE,APE1,APEN,APEX,APX,HAP1,REF1
General protein information	Preferred Names apurinic/apyrimidinic endodeoxyribonuclease 1 Names DNA-(apurinic or apyrimidinic site) lyase AP endonuclease class I AP lyase APEX nuclease (multifunctional DNA repair enzyme) 1 apurinic-apyrimidinic endonuclease 1 apurinic/apyrimidinic (abasic) endonuclease deoxyribonuclease (apurinic or apyrimidinic) protein REF-1 redox factor-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q11.2
Summary	Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008].
Disorder MIM:	107748

Canis lupus familiaris (dog)	APEX1	NP_001138591.1
Mus musculus (house mouse)	Apex1	NP_033817.1
Gallus gallus (chicken)	APEX1	NP_001171688.1
Arabidopsis thaliana (thale cress)	ARP	NP_181677.1
Pan troglodytes (chimpanzee)	APEX1	NP_001074954.1
	APEX1	XP_001090240.1
Rattus norvegicus (Norway rat)	Apex1	NP_077062.1
Oryza sativa (rice)	Os01g0801000	NP_001044537.1
Bos taurus (cattle)	APEX1	NP_788782.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009587	XP_318609.4
Xenopus tropicalis (tropical clawed frog)	apex1	NP_989307.1
Homo sapiens (human)	APEX1	NP_001231178.1
Danio rerio (zebrafish)	apex1	NP_998586.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

APEX1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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