HNRNPAB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HNRNPAB
Entrez Gene ID	3182
Full Name	heterogeneous nuclear ribonucleoprotein A/B
Synonyms	ABBP1,HNRPAB
General protein information	Preferred Names heterogeneous nuclear ribonucleoprotein A/B Names heterogeneous nuclear ribonucleoprotein A/B ABBP-1 APOBEC1-binding protein 1 apobec-1 binding protein 1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1-binding protein 1 hnRNP A/B hnRNP type A/B protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q35.3
Summary	This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	602688

mRNA and Protein(s)

mRNA	Protein	Name
NM_031266.2	NP_112556.2	heterogeneous nuclear ribonucleoprotein A/B isoform a
NM_031266.3	NP_112556.2	heterogeneous nuclear ribonucleoprotein A/B isoform a
NM_004499.3	NP_004490.2	heterogeneous nuclear ribonucleoprotein A/B isoform b
NM_004499.4	NP_004490.2	heterogeneous nuclear ribonucleoprotein A/B isoform b

Pathways from BioSystems

Homologies

Bos taurus (cattle)	HNRNPAB	NP_001035612.1
Danio rerio (zebrafish)	hnrnpaba	NP_997752.2
	HNRNPAB	XP_001096907.1
Rattus norvegicus (Norway rat)	LOC100910156	XP_003750865.1
Mus musculus (house mouse)	Hnrnpab	NP_001041526.1
Gallus gallus (chicken)	HNRNPAB	NP_990659.1
Xenopus tropicalis (tropical clawed frog)	hnrnpab	NP_001039236.1
Homo sapiens (human)	HNRNPAB	NP_112556.2
Danio rerio (zebrafish)	hnrnpabb	NP_998467.1

Gene Ontology
Bibliography

Related articles in PubMed

[High expression of hnRNPAB/Kap1 together promote poor prognosis in HCC].
Zhou ZJ, Wang XY, Xu XY, Hu ZQ, Chen EB, Zhou SL, Wu WZ, Zhou J, Fan J, Dai Z
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology25(6)452-457(2017 Jun)

Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.
Crisci A, Raleff F, Bagdiul I, Raabe M, Urlaub H, Rain JC, Kr?mer A
Nucleic acids research43(21)10456-73(2015 Dec)

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Jefferson M, Donaszi-Ivanov A, Pollen S, Dalmay T, Saalbach G, Powell PP
Journal of virology88(18)10340-53(2014 Sep)

HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL.
Zhou ZJ, Dai Z, Zhou SL, Hu ZQ, Chen Q, Zhao YM, Shi YH, Gao Q, Wu WZ, Qiu SJ, Zhou J, Fan J
Cancer research74(10)2750-62(2014 May)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Findings define HNRNPAB as an activator of EMT and metastasis in HCC that predicts poor clinical outcomes.
Title: HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL.

physical association of p63alpha and ABBP1 led to a specific shift of FGFR-2 alternative splicing toward the K-SAM isoform essential for epithelial differentiation
Title: P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome.

The following HNRNPAB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HNRNPAB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30310	NM_004499.4 Latest version!	Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu30260	NM_031266.3 Latest version!	Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$216.30 $309.00
View Old Accession Versions >>
OHu30260	NM_031266.2	Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$216.30 $309.00
OHu30310	NM_004499.3	Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HNRNPAB ( NM_004499.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004490.2 Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30310
Clone ID Related Accession (Same CDS sequence)	NM_004499.3 , NM_004499.4
Accession Version	NM_004499.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	heterogeneous nuclear ribonucleoprotein A/B isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK097657.1, BC001616.1, BC004561.2, BC036708.2 and AI199152.1. On Nov 22, 2004 this sequence version replaced NM_004499.2. Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region compared to variant 1. The resulting protein (isoform b) is shorter, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.93112.1, SRR1163658.169741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGAAG CGGGCGAGGA GCAGCCCATG GAGACGACGG GCGCCACCGA GAACGGACAT 
GAGGCCGTCC CCGAAGGCGA GTCGCCGGCC GGGGCTGGCA CGGGCGCCGC GGCGGGGGCT 
GGAGGCGCGA CCGCGGCGCC CCCGAGCGGG AATCAGAACG GCGCCGAGGG CGACCAGATC 
AACGCCAGCA AGAACGAGGA GGACGCGGGA AAAATGTTCG TTGGTGGCCT GAGCTGGGAT 
ACTAGCAAAA AAGATTTAAA AGACTATTTT ACTAAATTTG GAGAGGTCGT TGACTGTACA 
ATAAAAATGG ATCCCAACAC TGGACGGTCA AGAGGGTTTG GGTTTATCCT GTTCAAAGAT 
GCAGCCAGTG TGGAGAAGGT CCTAGACCAG AAGGAGCACA GGCTGGATGG CCGTGTCATT 
GACCCTAAAA AGGCCATGGC TATGAAGAAG GACCCGGTGA AGAAAATCTT CGTTGGGGGT 
CTGAATCCTG AAGCCACTGA GGAAAAGATC AGGGAGTACT TTGGCGAGTT TGGGGAGATT 
GAGGCCATTG AATTGCCAAT GGATCCAAAG TTGAACAAAA GACGAGGTTT TGTGTTTATC 
ACCTTTAAAG AAGAAGAACC CGTGAAGAAG GTTCTGGAGA AAAAGTTCCA TACTGTCAGT 
GGAAGCAAGT GTGAGATCAA GGTGGCCCAG CCCAAAGAAG TCTATCAGCA GCAGCAGTAT 
GGCTCTGGGG GCCGTGGAAA CCGCAACCGA GGGAACCGAG GCAGCGGAGG TGGTGGTGGA 
GGTGGAGGTC AGGGTAGTAC AAACTACGGC AAGAGCCAGC GACGTGGTGG CCATCAGAAT 
AACTACAAGC CATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004490.2
CDS	258..1115
Translation	MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQGSTNYGKSQRRGGHQNNYKPY

Target ORF information:

RefSeq Version	NM_004499.3
Organism	Homo sapiens(human)
Definition	Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004499.3

ORF Insert Sequence:

ATGTCGGAAG CGGGCGAGGA GCAGCCCATG GAGACGACGG GCGCCACCGA GAACGGACAT 
GAGGCCGTCC CCGAAGGCGA GTCGCCGGCC GGGGCTGGCA CGGGCGCCGC GGCGGGGGCT 
GGAGGCGCGA CCGCGGCGCC CCCGAGCGGG AATCAGAACG GCGCCGAGGG CGACCAGATC 
AACGCCAGCA AGAACGAGGA GGACGCGGGA AAAATGTTCG TTGGTGGCCT GAGCTGGGAT 
ACTAGCAAAA AAGATTTAAA AGACTATTTT ACTAAATTTG GAGAGGTCGT TGACTGTACA 
ATAAAAATGG ATCCCAACAC TGGACGGTCA AGAGGGTTTG GGTTTATCCT GTTCAAAGAT 
GCAGCCAGTG TGGAGAAGGT CCTAGACCAG AAGGAGCACA GGCTGGATGG CCGTGTCATT 
GACCCTAAAA AGGCCATGGC TATGAAGAAG GACCCGGTGA AGAAAATCTT CGTTGGGGGT 
CTGAATCCTG AAGCCACTGA GGAAAAGATC AGGGAGTACT TTGGCGAGTT TGGGGAGATT 
GAGGCCATTG AATTGCCAAT GGATCCAAAG TTGAACAAAA GACGAGGTTT TGTGTTTATC 
ACCTTTAAAG AAGAAGAACC CGTGAAGAAG GTTCTGGAGA AAAAGTTCCA TACTGTCAGT 
GGAAGCAAGT GTGAGATCAA GGTGGCCCAG CCCAAAGAAG TCTATCAGCA GCAGCAGTAT 
GGCTCTGGGG GCCGTGGAAA CCGCAACCGA GGGAACCGAG GCAGCGGAGG TGGTGGTGGA 
GGTGGAGGTC AGGGTAGTAC AAACTACGGC AAGAGCCAGC GACGTGGTGG CCATCAGAAT 
AACTACAAGC CATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNRNPAB ( NM_004499.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004490.2 Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30310
Clone ID Related Accession (Same CDS sequence)	NM_004499.3 , NM_004499.4
Accession Version	NM_004499.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	heterogeneous nuclear ribonucleoprotein A/B isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK097657.1, BC001616.1 and BC004561.2. On May 31, 2019 this sequence version replaced NM_004499.3. Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region compared to variant 1. The resulting protein (isoform b) is shorter, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004561.2, SRR1163658.169741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGAAG CGGGCGAGGA GCAGCCCATG GAGACGACGG GCGCCACCGA GAACGGACAT 
GAGGCCGTCC CCGAAGGCGA GTCGCCGGCC GGGGCTGGCA CGGGCGCCGC GGCGGGGGCT 
GGAGGCGCGA CCGCGGCGCC CCCGAGCGGG AATCAGAACG GCGCCGAGGG CGACCAGATC 
AACGCCAGCA AGAACGAGGA GGACGCGGGA AAAATGTTCG TTGGTGGCCT GAGCTGGGAT 
ACTAGCAAAA AAGATTTAAA AGACTATTTT ACTAAATTTG GAGAGGTCGT TGACTGTACA 
ATAAAAATGG ATCCCAACAC TGGACGGTCA AGAGGGTTTG GGTTTATCCT GTTCAAAGAT 
GCAGCCAGTG TGGAGAAGGT CCTAGACCAG AAGGAGCACA GGCTGGATGG CCGTGTCATT 
GACCCTAAAA AGGCCATGGC TATGAAGAAG GACCCGGTGA AGAAAATCTT CGTTGGGGGT 
CTGAATCCTG AAGCCACTGA GGAAAAGATC AGGGAGTACT TTGGCGAGTT TGGGGAGATT 
GAGGCCATTG AATTGCCAAT GGATCCAAAG TTGAACAAAA GACGAGGTTT TGTGTTTATC 
ACCTTTAAAG AAGAAGAACC CGTGAAGAAG GTTCTGGAGA AAAAGTTCCA TACTGTCAGT 
GGAAGCAAGT GTGAGATCAA GGTGGCCCAG CCCAAAGAAG TCTATCAGCA GCAGCAGTAT 
GGCTCTGGGG GCCGTGGAAA CCGCAACCGA GGGAACCGAG GCAGCGGAGG TGGTGGTGGA 
GGTGGAGGTC AGGGTAGTAC AAACTACGGC AAGAGCCAGC GACGTGGTGG CCATCAGAAT 
AACTACAAGC CATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004490.2
CDS	232..1089
Translation	MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQGSTNYGKSQRRGGHQNNYKPY

Target ORF information:

RefSeq Version	NM_004499.4
Organism	Homo sapiens(human)
Definition	Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004499.4

ORF Insert Sequence:

ATGTCGGAAG CGGGCGAGGA GCAGCCCATG GAGACGACGG GCGCCACCGA GAACGGACAT 
GAGGCCGTCC CCGAAGGCGA GTCGCCGGCC GGGGCTGGCA CGGGCGCCGC GGCGGGGGCT 
GGAGGCGCGA CCGCGGCGCC CCCGAGCGGG AATCAGAACG GCGCCGAGGG CGACCAGATC 
AACGCCAGCA AGAACGAGGA GGACGCGGGA AAAATGTTCG TTGGTGGCCT GAGCTGGGAT 
ACTAGCAAAA AAGATTTAAA AGACTATTTT ACTAAATTTG GAGAGGTCGT TGACTGTACA 
ATAAAAATGG ATCCCAACAC TGGACGGTCA AGAGGGTTTG GGTTTATCCT GTTCAAAGAT 
GCAGCCAGTG TGGAGAAGGT CCTAGACCAG AAGGAGCACA GGCTGGATGG CCGTGTCATT 
GACCCTAAAA AGGCCATGGC TATGAAGAAG GACCCGGTGA AGAAAATCTT CGTTGGGGGT 
CTGAATCCTG AAGCCACTGA GGAAAAGATC AGGGAGTACT TTGGCGAGTT TGGGGAGATT 
GAGGCCATTG AATTGCCAAT GGATCCAAAG TTGAACAAAA GACGAGGTTT TGTGTTTATC 
ACCTTTAAAG AAGAAGAACC CGTGAAGAAG GTTCTGGAGA AAAAGTTCCA TACTGTCAGT 
GGAAGCAAGT GTGAGATCAA GGTGGCCCAG CCCAAAGAAG TCTATCAGCA GCAGCAGTAT 
GGCTCTGGGG GCCGTGGAAA CCGCAACCGA GGGAACCGAG GCAGCGGAGG TGGTGGTGGA 
GGTGGAGGTC AGGGTAGTAC AAACTACGGC AAGAGCCAGC GACGTGGTGG CCATCAGAAT 
AACTACAAGC CATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNRNPAB ( NM_031266.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_112556.2 Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30260
Clone ID Related Accession (Same CDS sequence)	NM_031266.2 , NM_031266.3
Accession Version	NM_031266.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	heterogeneous nuclear ribonucleoprotein A/B isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK097657.1, BC001616.1, BC036708.2 and AI199152.1. On Nov 22, 2004 this sequence version replaced NM_031266.1. Transcript Variant: This variant (1) encodes the full length isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK097657.1, SRR1163655.50005.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGAAG CGGGCGAGGA GCAGCCCATG GAGACGACGG GCGCCACCGA GAACGGACAT 
GAGGCCGTCC CCGAAGGCGA GTCGCCGGCC GGGGCTGGCA CGGGCGCCGC GGCGGGGGCT 
GGAGGCGCGA CCGCGGCGCC CCCGAGCGGG AATCAGAACG GCGCCGAGGG CGACCAGATC 
AACGCCAGCA AGAACGAGGA GGACGCGGGA AAAATGTTCG TTGGTGGCCT GAGCTGGGAT 
ACTAGCAAAA AAGATTTAAA AGACTATTTT ACTAAATTTG GAGAGGTCGT TGACTGTACA 
ATAAAAATGG ATCCCAACAC TGGACGGTCA AGAGGGTTTG GGTTTATCCT GTTCAAAGAT 
GCAGCCAGTG TGGAGAAGGT CCTAGACCAG AAGGAGCACA GGCTGGATGG CCGTGTCATT 
GACCCTAAAA AGGCCATGGC TATGAAGAAG GACCCGGTGA AGAAAATCTT CGTTGGGGGT 
CTGAATCCTG AAGCCACTGA GGAAAAGATC AGGGAGTACT TTGGCGAGTT TGGGGAGATT 
GAGGCCATTG AATTGCCAAT GGATCCAAAG TTGAACAAAA GACGAGGTTT TGTGTTTATC 
ACCTTTAAAG AAGAAGAACC CGTGAAGAAG GTTCTGGAGA AAAAGTTCCA TACTGTCAGT 
GGAAGCAAGT GTGAGATCAA GGTGGCCCAG CCCAAAGAAG TCTATCAGCA GCAGCAGTAT 
GGCTCTGGGG GCCGTGGAAA CCGCAACCGA GGGAACCGAG GCAGCGGAGG TGGTGGTGGA 
GGTGGAGGTC AGAGTCAGAG TTGGAATCAG GGCTACGGCA ACTACTGGAA CCAGGGCTAC 
GGCTACCAGC AGGGCTACGG GCCTGGCTAT GGCGGCTACG ACTACTCGCC CTATGGCTAT 
TACGGCTACG GCCCCGGCTA CGACTACAGT CAGGGTAGTA CAAACTACGG CAAGAGCCAG 
CGACGTGGTG GCCATCAGAA TAACTACAAG CCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112556.2
CDS	258..1256
Translation	MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY

Target ORF information:

RefSeq Version	NM_031266.2
Organism	Homo sapiens(human)
Definition	Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031266.2

ORF Insert Sequence:

ATGTCGGAAG CGGGCGAGGA GCAGCCCATG GAGACGACGG GCGCCACCGA GAACGGACAT 
GAGGCCGTCC CCGAAGGCGA GTCGCCGGCC GGGGCTGGCA CGGGCGCCGC GGCGGGGGCT 
GGAGGCGCGA CCGCGGCGCC CCCGAGCGGG AATCAGAACG GCGCCGAGGG CGACCAGATC 
AACGCCAGCA AGAACGAGGA GGACGCGGGA AAAATGTTCG TTGGTGGCCT GAGCTGGGAT 
ACTAGCAAAA AAGATTTAAA AGACTATTTT ACTAAATTTG GAGAGGTCGT TGACTGTACA 
ATAAAAATGG ATCCCAACAC TGGACGGTCA AGAGGGTTTG GGTTTATCCT GTTCAAAGAT 
GCAGCCAGTG TGGAGAAGGT CCTAGACCAG AAGGAGCACA GGCTGGATGG CCGTGTCATT 
GACCCTAAAA AGGCCATGGC TATGAAGAAG GACCCGGTGA AGAAAATCTT CGTTGGGGGT 
CTGAATCCTG AAGCCACTGA GGAAAAGATC AGGGAGTACT TTGGCGAGTT TGGGGAGATT 
GAGGCCATTG AATTGCCAAT GGATCCAAAG TTGAACAAAA GACGAGGTTT TGTGTTTATC 
ACCTTTAAAG AAGAAGAACC CGTGAAGAAG GTTCTGGAGA AAAAGTTCCA TACTGTCAGT 
GGAAGCAAGT GTGAGATCAA GGTGGCCCAG CCCAAAGAAG TCTATCAGCA GCAGCAGTAT 
GGCTCTGGGG GCCGTGGAAA CCGCAACCGA GGGAACCGAG GCAGCGGAGG TGGTGGTGGA 
GGTGGAGGTC AGAGTCAGAG TTGGAATCAG GGCTACGGCA ACTACTGGAA CCAGGGCTAC 
GGCTACCAGC AGGGCTACGG GCCTGGCTAT GGCGGCTACG ACTACTCGCC CTATGGCTAT 
TACGGCTACG GCCCCGGCTA CGACTACAGT CAGGGTAGTA CAAACTACGG CAAGAGCCAG 
CGACGTGGTG GCCATCAGAA TAACTACAAG CCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HNRNPAB ( NM_031266.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_112556.2 Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30260
Clone ID Related Accession (Same CDS sequence)	NM_031266.2 , NM_031266.3
Accession Version	NM_031266.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	heterogeneous nuclear ribonucleoprotein A/B isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK097657.1 and BC001616.1. On Nov 22, 2018 this sequence version replaced NM_031266.2. Transcript Variant: This variant (1) encodes the full length isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223425.1, AK097657.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000358344.8/ ENSP00000351108.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGGAAG CGGGCGAGGA GCAGCCCATG GAGACGACGG GCGCCACCGA GAACGGACAT 
GAGGCCGTCC CCGAAGGCGA GTCGCCGGCC GGGGCTGGCA CGGGCGCCGC GGCGGGGGCT 
GGAGGCGCGA CCGCGGCGCC CCCGAGCGGG AATCAGAACG GCGCCGAGGG CGACCAGATC 
AACGCCAGCA AGAACGAGGA GGACGCGGGA AAAATGTTCG TTGGTGGCCT GAGCTGGGAT 
ACTAGCAAAA AAGATTTAAA AGACTATTTT ACTAAATTTG GAGAGGTCGT TGACTGTACA 
ATAAAAATGG ATCCCAACAC TGGACGGTCA AGAGGGTTTG GGTTTATCCT GTTCAAAGAT 
GCAGCCAGTG TGGAGAAGGT CCTAGACCAG AAGGAGCACA GGCTGGATGG CCGTGTCATT 
GACCCTAAAA AGGCCATGGC TATGAAGAAG GACCCGGTGA AGAAAATCTT CGTTGGGGGT 
CTGAATCCTG AAGCCACTGA GGAAAAGATC AGGGAGTACT TTGGCGAGTT TGGGGAGATT 
GAGGCCATTG AATTGCCAAT GGATCCAAAG TTGAACAAAA GACGAGGTTT TGTGTTTATC 
ACCTTTAAAG AAGAAGAACC CGTGAAGAAG GTTCTGGAGA AAAAGTTCCA TACTGTCAGT 
GGAAGCAAGT GTGAGATCAA GGTGGCCCAG CCCAAAGAAG TCTATCAGCA GCAGCAGTAT 
GGCTCTGGGG GCCGTGGAAA CCGCAACCGA GGGAACCGAG GCAGCGGAGG TGGTGGTGGA 
GGTGGAGGTC AGAGTCAGAG TTGGAATCAG GGCTACGGCA ACTACTGGAA CCAGGGCTAC 
GGCTACCAGC AGGGCTACGG GCCTGGCTAT GGCGGCTACG ACTACTCGCC CTATGGCTAT 
TACGGCTACG GCCCCGGCTA CGACTACAGT CAGGGTAGTA CAAACTACGG CAAGAGCCAG 
CGACGTGGTG GCCATCAGAA TAACTACAAG CCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112556.2
CDS	232..1230
Translation	MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY

Target ORF information:

RefSeq Version	NM_031266.3
Organism	Homo sapiens(human)
Definition	Homo sapiens heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031266.3

ORF Insert Sequence:

ATGTCGGAAG CGGGCGAGGA GCAGCCCATG GAGACGACGG GCGCCACCGA GAACGGACAT 
GAGGCCGTCC CCGAAGGCGA GTCGCCGGCC GGGGCTGGCA CGGGCGCCGC GGCGGGGGCT 
GGAGGCGCGA CCGCGGCGCC CCCGAGCGGG AATCAGAACG GCGCCGAGGG CGACCAGATC 
AACGCCAGCA AGAACGAGGA GGACGCGGGA AAAATGTTCG TTGGTGGCCT GAGCTGGGAT 
ACTAGCAAAA AAGATTTAAA AGACTATTTT ACTAAATTTG GAGAGGTCGT TGACTGTACA 
ATAAAAATGG ATCCCAACAC TGGACGGTCA AGAGGGTTTG GGTTTATCCT GTTCAAAGAT 
GCAGCCAGTG TGGAGAAGGT CCTAGACCAG AAGGAGCACA GGCTGGATGG CCGTGTCATT 
GACCCTAAAA AGGCCATGGC TATGAAGAAG GACCCGGTGA AGAAAATCTT CGTTGGGGGT 
CTGAATCCTG AAGCCACTGA GGAAAAGATC AGGGAGTACT TTGGCGAGTT TGGGGAGATT 
GAGGCCATTG AATTGCCAAT GGATCCAAAG TTGAACAAAA GACGAGGTTT TGTGTTTATC 
ACCTTTAAAG AAGAAGAACC CGTGAAGAAG GTTCTGGAGA AAAAGTTCCA TACTGTCAGT 
GGAAGCAAGT GTGAGATCAA GGTGGCCCAG CCCAAAGAAG TCTATCAGCA GCAGCAGTAT 
GGCTCTGGGG GCCGTGGAAA CCGCAACCGA GGGAACCGAG GCAGCGGAGG TGGTGGTGGA 
GGTGGAGGTC AGAGTCAGAG TTGGAATCAG GGCTACGGCA ACTACTGGAA CCAGGGCTAC 
GGCTACCAGC AGGGCTACGG GCCTGGCTAT GGCGGCTACG ACTACTCGCC CTATGGCTAT 
TACGGCTACG GCCCCGGCTA CGACTACAGT CAGGGTAGTA CAAACTACGG CAAGAGCCAG 
CGACGTGGTG GCCATCAGAA TAACTACAAG CCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

[High expression of hnRNPAB/Kap1 together promote poor prognosis in HCC].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology25(6)452-457(2017 Jun)
Zhou ZJ,Wang XY,Xu XY,Hu ZQ,Chen EB,Zhou SL,Wu WZ,Zhou J,Fan J,Dai Z

Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.
Nucleic acids research43(21)10456-73(2015 Dec)
Crisci A,Raleff F,Bagdiul I,Raabe M,Urlaub H,Rain JC,Kr?mer A

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Journal of virology88(18)10340-53(2014 Sep)
Jefferson M,Donaszi-Ivanov A,Pollen S,Dalmay T,Saalbach G,Powell PP

HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL.
Cancer research74(10)2750-62(2014 May)
Zhou ZJ,Dai Z,Zhou SL,Hu ZQ,Chen Q,Zhao YM,Shi YH,Gao Q,Wu WZ,Qiu SJ,Zhou J,Fan J

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

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HNRNPAB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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