NUDT2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NUDT2
Entrez Gene ID	318
Full Name	nudix hydrolase 2
Synonyms	APAH1
General protein information	Preferred Names nudix hydrolase 2 Names bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Ap4A hydrolase 1 Ap4Aase bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase diadenosine tetraphosphatase nucleoside diphosphate-linked moiety X motif 2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 nudix motif 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p13.3
Summary	This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011].
Disorder MIM:	602852

mRNA and Protein(s)

mRNA	Protein	Name
NM_147172.2	NP_671701.1	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
NM_147173.3	NP_671702.1	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
NM_001244390.1	NP_001231319.1	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
XM_024447528.1	XP_024303296.1	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X1
NM_147173.2	NP_671702.1	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
NM_001161.4	NP_001152.1	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
NM_001161.5	NP_001152.1	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
NM_147172.3	NP_671701.1	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	NUDT2	XP_520541.1
Drosophila melanogaster (fruit fly)	Apf	NP_723505.2
	NUDT2	XP_001098004.1
Canis lupus familiaris (dog)	NUDT2	XP_005626774.1
Gallus gallus (chicken)	NUDT2	XP_424973.1
Danio rerio (zebrafish)	nudt2	NP_001002323.1
Xenopus tropicalis (tropical clawed frog)	nudt2	NP_001006918.1
Rattus norvegicus (Norway rat)	Nudt2	NP_997479.1
Bos taurus (cattle)	NUDT2	NP_001070570.1
Homo sapiens (human)	NUDT2	NP_001152.1
Mus musculus (house mouse)	Nudt2	NP_079815.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008495	XP_316948.4
Caenorhabditis elegans (roundworm)	ndx-4	NP_493413.1
Xenopus tropicalis (tropical clawed frog)	LOC101734499	XP_004911386.1

Gene Ontology
Bibliography

Related articles in PubMed

Nudix-type motif 2 contributes to cancer proliferation through the regulation of Rag GTPase-mediated mammalian target of rapamycin complex 1 localization.
Kwon O, Kwak D, Ha SH, Jeon H, Park M, Chang Y, Suh PG, Ryu SH
Cellular signalling3224-35(2017 Apr)

NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes.
Marriott AS, Vasieva O, Fang Y, Copeland NA, McLennan AG, Jones NJ
PloS one11(5)e0154674(2016)

Crystal structure of wild-type and mutant human Ap4A hydrolase.
Ge H, Chen X, Yang W, Niu L, Teng M
Biochemical and biophysical research communications432(1)16-21(2013 Mar)

Nudix-type motif 2 in human breast carcinoma: a potent prognostic factor associated with cell proliferation.
Oka K, Suzuki T, Onodera Y, Miki Y, Takagi K, Nagasaki S, Akahira J, Ishida T, Watanabe M, Hirakawa H, Ohuchi N, Sasano H
International journal of cancer128(8)1770-82(2011 Apr)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NUDT2 is a novel complex formation enhancing factor regulating mTORC1-Rag GTPase signaling that is crucial for cell growth control.
Title: Nudix-type motif 2 contributes to cancer proliferation through the regulation of Rag GTPase-mediated mammalian target of rapamycin complex 1 localization.

Regulation of gene expression is one of several roles proposed for the stress-induced nucleotide diadenosine tetraphosphate (Ap4A). We have examined this directly by a comparative RNA-Seq analysis of KBM-7 chronic myelogenous leukemia cells and KBM-7 cells in which the NUDT2 Ap4A hydrolase gene had been disrupted (NuKO cells), causing a 175-fold increase in intracellular Ap4A.
Title: NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes.

This paper presents the crystal structure of wild-type and E58A mutant human Ap4A hydrolase.
Title: Crystal structure of wild-type and mutant human Ap4A hydrolase.

High NUDT2 is associated with breast carcinoma.
Title: Nudix-type motif 2 in human breast carcinoma: a potent prognostic factor associated with cell proliferation.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following NUDT2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NUDT2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02361	NM_147173.3 Latest version!	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02361	NM_001161.5 Latest version!	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02361	NM_147172.3 Latest version!	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02361	NM_001244390.1 Latest version!	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02361	XM_024447528.1 Latest version!	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu02361	NM_147173.2	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02361	NM_001161.4	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02361	NM_147172.2	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NUDT2 ( NM_147172.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_671701.1 Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02361
Clone ID Related Accession (Same CDS sequence)	NM_147172.2 , NM_147173.3 , NM_001244390.1 , XM_024447528.1 , NM_147173.2 , NM_001161.4 , NM_001161.5 , NM_147172.3
Accession Version	NM_147172.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA398857.1, BG622439.1 and BQ007098.1. On Sep 16, 2011 this sequence version replaced NM_147172.1. Transcript Variant: This variant (2) uses an alternate splice site on a 5' non-coding exon, compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG622439.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_671701.1
CDS	288..731
Translation	MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA

Target ORF information:

RefSeq Version	NM_147172.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_147172.2

ORF Insert Sequence:

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT2 ( NM_147173.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_671702.1 Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu02361
Clone ID Related Accession (Same CDS sequence)	NM_147172.2 , NM_147173.3 , NM_001244390.1 , XM_024447528.1 , NM_147173.2 , NM_001161.4 , NM_001161.5 , NM_147172.3
Accession Version	NM_147173.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA398857.1, DN992111.1 and BQ007098.1. On May 31, 2019 this sequence version replaced NM_147173.2. Transcript Variant: This variant (3) lacks a 5' non-coding exon, compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138528.65039.1, DRR138524.1023219.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_671702.1
CDS	183..626
Translation	MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA

Target ORF information:

RefSeq Version	NM_147173.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_147173.3

ORF Insert Sequence:

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT2 ( NM_001244390.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231319.1 Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu02361
Clone ID Related Accession (Same CDS sequence)	NM_147172.2 , NM_147173.3 , NM_001244390.1 , XM_024447528.1 , NM_147173.2 , NM_001161.4 , NM_001161.5 , NM_147172.3
Accession Version	NM_001244390.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA398857.1, AA310093.1 and BQ007098.1. Transcript Variant: This variant (4) lacks two alternate 5' UTR exons compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.74112.1, SRR1163658.294699.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231319.1
CDS	111..554
Translation	MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA

Target ORF information:

RefSeq Version	NM_001244390.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244390.1

ORF Insert Sequence:

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT2 ( NM_147173.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_671702.1 Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu02361
Clone ID Related Accession (Same CDS sequence)	NM_147172.2 , NM_147173.3 , NM_001244390.1 , XM_024447528.1 , NM_147173.2 , NM_001161.4 , NM_001161.5 , NM_147172.3
Accession Version	NM_147173.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA398857.1, DN992111.1 and BQ007098.1. On Sep 16, 2011 this sequence version replaced NM_147173.1. Transcript Variant: This variant (3) lacks a 5' non-coding exon, compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.190295.1, SRR1163658.523779.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_671702.1
CDS	246..689
Translation	MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA

Target ORF information:

RefSeq Version	NM_147173.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_147173.2

ORF Insert Sequence:

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT2 ( NM_001161.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001152.1 Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02361
Clone ID Related Accession (Same CDS sequence)	NM_147172.2 , NM_147173.3 , NM_001244390.1 , XM_024447528.1 , NM_147173.2 , NM_001161.4 , NM_001161.5 , NM_147172.3
Accession Version	NM_001161.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA398857.1, BG825757.1, AL356494.13 and BQ007098.1. On Sep 16, 2011 this sequence version replaced NM_001161.3. Transcript Variant: This variant (1) is the full-length transcript. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.532760.1, BM802700.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001152.1
CDS	359..802
Translation	MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA

Target ORF information:

RefSeq Version	NM_001161.4
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161.4

ORF Insert Sequence:

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT2 ( NM_001161.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001152.1 Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 1, mRNA.

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CloneID	OHu02361
Clone ID Related Accession (Same CDS sequence)	NM_147172.2 , NM_147173.3 , NM_001244390.1 , XM_024447528.1 , NM_147173.2 , NM_001161.4 , NM_001161.5 , NM_147172.3
Accession Version	NM_001161.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA398857.1, BG825757.1, AL356494.13 and BQ007098.1. On Nov 23, 2018 this sequence version replaced NM_001161.4. Transcript Variant: This variant (1) is the full-length transcript. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189664.93506.1, SRR1163655.532760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000379158.7/ ENSP00000368455.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001152.1
CDS	296..739
Translation	MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA

Target ORF information:

RefSeq Version	NM_001161.5
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161.5

ORF Insert Sequence:

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT2 ( NM_147172.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_671701.1 Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02361
Clone ID Related Accession (Same CDS sequence)	NM_147172.2 , NM_147173.3 , NM_001244390.1 , XM_024447528.1 , NM_147173.2 , NM_001161.4 , NM_001161.5 , NM_147172.3
Accession Version	NM_147172.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG622439.1 and BQ007098.1. On May 31, 2019 this sequence version replaced NM_147172.2. Transcript Variant: This variant (2) uses an alternate splice site on a 5' non-coding exon, compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG622439.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_671701.1
CDS	225..668
Translation	MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA

Target ORF information:

RefSeq Version	NM_147172.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_147172.3

ORF Insert Sequence:

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUDT2 ( XM_024447528.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024303296.1 Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu02361
Clone ID Related Accession (Same CDS sequence)	NM_147172.2 , NM_147173.3 , NM_001244390.1 , XM_024447528.1 , NM_147173.2 , NM_001161.4 , NM_001161.5 , NM_147172.3
Accession Version	XM_024447528.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024303296.1
CDS	312..755
Translation	MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA

Target ORF information:

RefSeq Version	XM_024447528.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nudix hydrolase 2 (NUDT2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024447528.1

ORF Insert Sequence:

ATGGCCTTGA GAGCATGTGG CTTGATCATC TTCCGAAGAT GCCTCATTCC CAAAGTGGAC 
AACAATGCAA TTGAGTTTTT ACTGCTGCAG GCATCAGATG GCATTCATCA CTGGACTCCT 
CCCAAAGGCC ATGTGGAACC AGGAGAGGAT GACTTGGAAA CAGCCCTGAG GGAGACCCAA 
GAGGAAGCAG GCATAGAAGC AGGCCAGCTG ACCATTATTG AGGGGTTCAA AAGGGAACTC 
AATTATGTGG CCAGGAACAA GCCTAAAACA GTCATTTACT GGCTGGCGGA GGTGAAGGAC 
TATGACGTGG AGATCCGCCT CTCCCATGAG CACCAAGCCT ACCGCTGGCT GGGGCTGGAG 
GAGGCCTGCC AGTTGGCTCA GTTCAAGGAG ATGAAGGCAG CGCTCCAAGA AGGACACCAG 
TTTCTTTGCT CCATAGAGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nudix-type motif 2 contributes to cancer proliferation through the regulation of Rag GTPase-mediated mammalian target of rapamycin complex 1 localization.
Cellular signalling3224-35(2017 Apr)
Kwon O,Kwak D,Ha SH,Jeon H,Park M,Chang Y,Suh PG,Ryu SH

NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes.
PloS one11(5)e0154674(2016)
Marriott AS,Vasieva O,Fang Y,Copeland NA,McLennan AG,Jones NJ

Crystal structure of wild-type and mutant human Ap4A hydrolase.
Biochemical and biophysical research communications432(1)16-21(2013 Mar)
Ge H,Chen X,Yang W,Niu L,Teng M

Nudix-type motif 2 in human breast carcinoma: a potent prognostic factor associated with cell proliferation.
International journal of cancer128(8)1770-82(2011 Apr)
Oka K,Suzuki T,Onodera Y,Miki Y,Takagi K,Nagasaki S,Akahira J,Ishida T,Watanabe M,Hirakawa H,Ohuchi N,Sasano H

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

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NUDT2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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