Gene Symbol | HMGA1 |
Entrez Gene ID | 3159 |
Full Name | high mobility group AT-hook 1 |
Synonyms | HMG-R,HMGA1A,HMGIY |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016]. |
Disorder MIM: | |
Disorder Html: | {Diabetes mellitus, noninsulin-dependent, susceptibility to}, 125853 (3) |