HLX cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HLX
Entrez Gene ID	3142
Full Name	H2.0 like homeobox
Synonyms	HB24,HLX1
General protein information	Preferred Names H2.0 like homeobox Names H2.0-like homeobox protein H2.0-like homeo box-1 H2.0-like homeobox 1 homeobox protein HB24 homeobox protein HLX1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q41
Disorder MIM:	142995

mRNA and Protein(s)

mRNA	Protein	Name
NM_021958.3	NP_068777.1	H2.0-like homeobox protein
NM_021958.4	NP_068777.1	H2.0-like homeobox protein

Pathways from BioSystems

Homologies

	HLX	XP_001101930.1
Canis lupus familiaris (dog)	HLX	XP_005640993.1
Mus musculus (house mouse)	Hlx	NP_032276.1
Homo sapiens (human)	HLX	NP_068777.1
Pan troglodytes (chimpanzee)	HLX	XP_525068.2
Rattus norvegicus (Norway rat)	Hlx	NP_001071142.1
Danio rerio (zebrafish)	hlx1	NP_997866.1
Bos taurus (cattle)	HLX	NP_001094567.1
Xenopus tropicalis (tropical clawed frog)	hlx	XP_002936060.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of Homeobox Gene HLX and its Downstream Target Genes are Altered in Placentae From Discordant Twin Pregnancies.
Yuen N, Brennecke SP, Umstad MP, Yong HEJ, Borg AJ, Rajaraman G, Kalionis B, Murthi P
Twin research and human genetics : the official journal of the International Society for Twin Studies1-9(2017 Dec)

HLX is a candidate gene for a pattern of anomalies associated with congenital diaphragmatic hernia, short bowel, and asplenia.
Farrell SA, Sodhi S, Marshall CR, Guerin A, Slavotinek A, Paton T, Chong K, Sirkin WL, Scherer SW, B?rub?-Simard FA, Pilon N
American journal of medical genetics. Part A173(11)3070-3074(2017 Nov)

Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation.
Huang L, Pan D, Chen Q, Zhu LJ, Ou J, Wabitsch M, Wang YX
Nature communications8(1)68(2017 07)

Screening of Human cDNA Library Reveals Two differentiation-Related Genes, HHEX and HLX, as Promoters of Early Phase Reprogramming toward Pluripotency.
Yamakawa T, Sato Y, Matsumura Y, Kobayashi Y, Kawamura Y, Goshima N, Yamanaka S, Okita K
Stem cells (Dayton, Ohio)34(11)2661-2669(2016 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Prdm16 interacts with the transcription factor Hlx, which is stabilized in response to beta3-adrenergic signaling, to increase thermogenic gene expression and mitochondrial biogenesis in subcutaneous WAT.
Title: Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation.

HLX1 is significantly downregulated in HCC and suggests that HLX1 has suppressive effects on HCC growth and metastasis. Accordingly, HLX1 may act as a tumor suppressor in HCC.
Title: H2.0-like homeobox 1 acts as a tumor suppressor in hepatocellular carcinoma.

Studies have identified HLX as a novel key transcription factor involved in the regulation of early hematopoiesis and AML pathogenesis.
Title: HLX in AML: novel prognostic and therapeutic target.

Data suggest that HLX1 is downstream mediator of hepatocyte growth factor- (HGF-) induced cell survival, cell proliferation, and invasive properties of trophoblast cells; thus, both HGF and HLX1 appear to be involved in normal placental development.
Title: Hepatocyte growth factor regulates HLX1 gene expression to modulate HTR-8/SVneo trophoblast cells.

The expression levels of Hlx, T-bet, and IFN-gamma were significantly decreased.
Title: Downregulation of Hlx closely related to the decreased expressions of T-bet and Runx3 in patients with gastric cancer may be associated with a pathological event leading to the imbalance of Th1/Th2.

The following HLX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HLX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55963	NM_021958.4 Latest version!	Homo sapiens H2.0 like homeobox (HLX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu55963	NM_021958.3	Homo sapiens H2.0 like homeobox (HLX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HLX ( NM_021958.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_068777.1 Homo sapiens H2.0 like homeobox (HLX), mRNA.

Price & Availability↑

CloneID	OHu55963
Clone ID Related Accession (Same CDS sequence)	NM_021958.3 , NM_021958.4
Accession Version	NM_021958.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1467bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	H2.0-like homeobox protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA951303.1 and BC033808.1. On May 9, 2008 this sequence version replaced NM_021958.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK127923.1, BC007294.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCGCAG CCGGGCTGGC TCCCTTCTAC GCCTCCAACT TCAGCCTCTG GTCGGCCGCT 
TACTGCTCCT CGGCCGGCCC AGGCGGCTGC TCCTTCCCCT TGGACCCCGC CGCCGTCAAA 
AAGCCCTCCT TCTGCATCGC AGACATTCTG CACGCCGGCG TGGGGGATCT GGGGGCGGCC 
CCGGAGGGCC TGGCAGGGGC CTCGGCCGCC GCCCTCACCG CGCACTTGGG CTCGGTTCAC 
CCGCACGCCT CTTTCCAAGC GGCGGCCAGA TCCCCGCTTC GACCCACCCC AGTGGTGGCG 
CCCTCCGAAG TCCCGGCTGG CTTCCCGCAG CGGCTGTCTC CGCTCTCAGC CGCCTACCAC 
CACCATCACC CGCAACAACA ACAGCAGCAG CAACAGCCGC AGCAGCAACA GCCTCCGCCT 
CCGCCCCGGG CTGGCGCCCT GCAGCCCCCG GCCTCGGGGA CGCGAGTGGT TCCGAACCCC 
CACCACAGTG GCTCTGCCCC GGCCCCCTCC AGCAAAGACC TCAAATTTGG AATTGACCGC 
ATTTTATCTG CAGAATTTGA CCCAAAAGTC AAAGAAGGCA ACACGCTGAG AGATCTCACT 
TCCCTGCTAA CCGGTGGGCG GCCCGCCGGG GTGCACCTCT CAGGCCTGCA GCCCTCGGCC 
GGCCAGTTCT TCGCATCTCT AGATCCCATT AACGAGGCTT CTGCAATCCT GAGTCCCTTA 
AACTCGAACC CAAGAAATTC AGTTCAGCAT CAGTTCCAAG ACACGTTTCC AGGTCCCTAT 
GCTGTGCTCA CGAAGGACAC CATGCCGCAG ACGTACAAAA GGAAGCGTTC ATGGTCGCGC 
GCTGTGTTCT CCAACCTGCA GAGGAAAGGC CTGGAGAAAA GGTTTGAGAT TCAGAAGTAC 
GTGACCAAGC CGGACCGAAA GCAGCTGGCG GCGATGCTGG GCCTCACGGA CGCACAGGTG 
AAGGTGTGGT TCCAGAACCG GCGGATGAAG TGGCGGCACT CCAAGGAGGC CCAGGCCCAA 
AAGGACAAGG ACAAGGAGGC TGGCGAGAAG CCATCAGGTG GAGCCCCGGC TGCGGATGGC 
GAGCAGGACG AGAGGAGCCC CAGCCGTTCT GAAGGCGAGG CTGAGAGCGA GAGCAGCGAC 
TCCGAGTCCC TGGACATGGC CCCCAGCGAC ACGGAGCGGA CTGAGGGGAG TGAGCGTTCT 
CTGCACCAAA CAACAGTTAT TAAGGCCCCG GTCACTGGCG CCCTCATTAC CGCCAGCAGT 
GCTGGGAGTG GTGGGAGCAG CGGCGGCGGC GGCAATAGTT TCAGCTTCAG CAGCGCCAGC 
AGTCTTAGTA GCAGCAGCAC CAGTGCGGGT TGCGCCAGCA GCCTTGGCGG CGGCGGCGCC 
TCGGAGCTTC TCCCTGCAAC ACAGCCCACA GCCAGCAGCG CTCCCAAAAG CCCCGAGCCA 
GCCCAAGGCG CGCTTGGCTG CTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068777.1
CDS	458..1924
Translation	MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGDLGAAPEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEPAQGALGCL

Target ORF information:

RefSeq Version	NM_021958.3
Organism	Homo sapiens(human)
Definition	Homo sapiens H2.0 like homeobox (HLX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021958.3

ORF Insert Sequence:

ATGTTCGCAG CCGGGCTGGC TCCCTTCTAC GCCTCCAACT TCAGCCTCTG GTCGGCCGCT 
TACTGCTCCT CGGCCGGCCC AGGCGGCTGC TCCTTCCCCT TGGACCCCGC CGCCGTCAAA 
AAGCCCTCCT TCTGCATCGC AGACATTCTG CACGCCGGCG TGGGGGATCT GGGGGCGGCC 
CCGGAGGGCC TGGCAGGGGC CTCGGCCGCC GCCCTCACCG CGCACTTGGG CTCGGTTCAC 
CCGCACGCCT CTTTCCAAGC GGCGGCCAGA TCCCCGCTTC GACCCACCCC AGTGGTGGCG 
CCCTCCGAAG TCCCGGCTGG CTTCCCGCAG CGGCTGTCTC CGCTCTCAGC CGCCTACCAC 
CACCATCACC CGCAACAACA ACAGCAGCAG CAACAGCCGC AGCAGCAACA GCCTCCGCCT 
CCGCCCCGGG CTGGCGCCCT GCAGCCCCCG GCCTCGGGGA CGCGAGTGGT TCCGAACCCC 
CACCACAGTG GCTCTGCCCC GGCCCCCTCC AGCAAAGACC TCAAATTTGG AATTGACCGC 
ATTTTATCTG CAGAATTTGA CCCAAAAGTC AAAGAAGGCA ACACGCTGAG AGATCTCACT 
TCCCTGCTAA CCGGTGGGCG GCCCGCCGGG GTGCACCTCT CAGGCCTGCA GCCCTCGGCC 
GGCCAGTTCT TCGCATCTCT AGATCCCATT AACGAGGCTT CTGCAATCCT GAGTCCCTTA 
AACTCGAACC CAAGAAATTC AGTTCAGCAT CAGTTCCAAG ACACGTTTCC AGGTCCCTAT 
GCTGTGCTCA CGAAGGACAC CATGCCGCAG ACGTACAAAA GGAAGCGTTC ATGGTCGCGC 
GCTGTGTTCT CCAACCTGCA GAGGAAAGGC CTGGAGAAAA GGTTTGAGAT TCAGAAGTAC 
GTGACCAAGC CGGACCGAAA GCAGCTGGCG GCGATGCTGG GCCTCACGGA CGCACAGGTG 
AAGGTGTGGT TCCAGAACCG GCGGATGAAG TGGCGGCACT CCAAGGAGGC CCAGGCCCAA 
AAGGACAAGG ACAAGGAGGC TGGCGAGAAG CCATCAGGTG GAGCCCCGGC TGCGGATGGC 
GAGCAGGACG AGAGGAGCCC CAGCCGTTCT GAAGGCGAGG CTGAGAGCGA GAGCAGCGAC 
TCCGAGTCCC TGGACATGGC CCCCAGCGAC ACGGAGCGGA CTGAGGGGAG TGAGCGTTCT 
CTGCACCAAA CAACAGTTAT TAAGGCCCCG GTCACTGGCG CCCTCATTAC CGCCAGCAGT 
GCTGGGAGTG GTGGGAGCAG CGGCGGCGGC GGCAATAGTT TCAGCTTCAG CAGCGCCAGC 
AGTCTTAGTA GCAGCAGCAC CAGTGCGGGT TGCGCCAGCA GCCTTGGCGG CGGCGGCGCC 
TCGGAGCTTC TCCCTGCAAC ACAGCCCACA GCCAGCAGCG CTCCCAAAAG CCCCGAGCCA 
GCCCAAGGCG CGCTTGGCTG CTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLX ( NM_021958.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_068777.1 Homo sapiens H2.0 like homeobox (HLX), mRNA.

Price & Availability↑

CloneID	OHu55963
Clone ID Related Accession (Same CDS sequence)	NM_021958.3 , NM_021958.4
Accession Version	NM_021958.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1467bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	H2.0-like homeobox protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA951303.1 and BC033808.1. On Nov 23, 2018 this sequence version replaced NM_021958.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK127923.1, BC007294.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000366903.8/ ENSP00000355870.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTCGCAG CCGGGCTGGC TCCCTTCTAC GCCTCCAACT TCAGCCTCTG GTCGGCCGCT 
TACTGCTCCT CGGCCGGCCC AGGCGGCTGC TCCTTCCCCT TGGACCCCGC CGCCGTCAAA 
AAGCCCTCCT TCTGCATCGC AGACATTCTG CACGCCGGCG TGGGGGATCT GGGGGCGGCC 
CCGGAGGGCC TGGCAGGGGC CTCGGCCGCC GCCCTCACCG CGCACTTGGG CTCGGTTCAC 
CCGCACGCCT CTTTCCAAGC GGCGGCCAGA TCCCCGCTTC GACCCACCCC AGTGGTGGCG 
CCCTCCGAAG TCCCGGCTGG CTTCCCGCAG CGGCTGTCTC CGCTCTCAGC CGCCTACCAC 
CACCATCACC CGCAACAACA ACAGCAGCAG CAACAGCCGC AGCAGCAACA GCCTCCGCCT 
CCGCCCCGGG CTGGCGCCCT GCAGCCCCCG GCCTCGGGGA CGCGAGTGGT TCCGAACCCC 
CACCACAGTG GCTCTGCCCC GGCCCCCTCC AGCAAAGACC TCAAATTTGG AATTGACCGC 
ATTTTATCTG CAGAATTTGA CCCAAAAGTC AAAGAAGGCA ACACGCTGAG AGATCTCACT 
TCCCTGCTAA CCGGTGGGCG GCCCGCCGGG GTGCACCTCT CAGGCCTGCA GCCCTCGGCC 
GGCCAGTTCT TCGCATCTCT AGATCCCATT AACGAGGCTT CTGCAATCCT GAGTCCCTTA 
AACTCGAACC CAAGAAATTC AGTTCAGCAT CAGTTCCAAG ACACGTTTCC AGGTCCCTAT 
GCTGTGCTCA CGAAGGACAC CATGCCGCAG ACGTACAAAA GGAAGCGTTC ATGGTCGCGC 
GCTGTGTTCT CCAACCTGCA GAGGAAAGGC CTGGAGAAAA GGTTTGAGAT TCAGAAGTAC 
GTGACCAAGC CGGACCGAAA GCAGCTGGCG GCGATGCTGG GCCTCACGGA CGCACAGGTG 
AAGGTGTGGT TCCAGAACCG GCGGATGAAG TGGCGGCACT CCAAGGAGGC CCAGGCCCAA 
AAGGACAAGG ACAAGGAGGC TGGCGAGAAG CCATCAGGTG GAGCCCCGGC TGCGGATGGC 
GAGCAGGACG AGAGGAGCCC CAGCCGTTCT GAAGGCGAGG CTGAGAGCGA GAGCAGCGAC 
TCCGAGTCCC TGGACATGGC CCCCAGCGAC ACGGAGCGGA CTGAGGGGAG TGAGCGTTCT 
CTGCACCAAA CAACAGTTAT TAAGGCCCCG GTCACTGGCG CCCTCATTAC CGCCAGCAGT 
GCTGGGAGTG GTGGGAGCAG CGGCGGCGGC GGCAATAGTT TCAGCTTCAG CAGCGCCAGC 
AGTCTTAGTA GCAGCAGCAC CAGTGCGGGT TGCGCCAGCA GCCTTGGCGG CGGCGGCGCC 
TCGGAGCTTC TCCCTGCAAC ACAGCCCACA GCCAGCAGCG CTCCCAAAAG CCCCGAGCCA 
GCCCAAGGCG CGCTTGGCTG CTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068777.1
CDS	416..1882
Translation	MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGDLGAAPEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEPAQGALGCL

Target ORF information:

RefSeq Version	NM_021958.4
Organism	Homo sapiens(human)
Definition	Homo sapiens H2.0 like homeobox (HLX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021958.4

ORF Insert Sequence:

ATGTTCGCAG CCGGGCTGGC TCCCTTCTAC GCCTCCAACT TCAGCCTCTG GTCGGCCGCT 
TACTGCTCCT CGGCCGGCCC AGGCGGCTGC TCCTTCCCCT TGGACCCCGC CGCCGTCAAA 
AAGCCCTCCT TCTGCATCGC AGACATTCTG CACGCCGGCG TGGGGGATCT GGGGGCGGCC 
CCGGAGGGCC TGGCAGGGGC CTCGGCCGCC GCCCTCACCG CGCACTTGGG CTCGGTTCAC 
CCGCACGCCT CTTTCCAAGC GGCGGCCAGA TCCCCGCTTC GACCCACCCC AGTGGTGGCG 
CCCTCCGAAG TCCCGGCTGG CTTCCCGCAG CGGCTGTCTC CGCTCTCAGC CGCCTACCAC 
CACCATCACC CGCAACAACA ACAGCAGCAG CAACAGCCGC AGCAGCAACA GCCTCCGCCT 
CCGCCCCGGG CTGGCGCCCT GCAGCCCCCG GCCTCGGGGA CGCGAGTGGT TCCGAACCCC 
CACCACAGTG GCTCTGCCCC GGCCCCCTCC AGCAAAGACC TCAAATTTGG AATTGACCGC 
ATTTTATCTG CAGAATTTGA CCCAAAAGTC AAAGAAGGCA ACACGCTGAG AGATCTCACT 
TCCCTGCTAA CCGGTGGGCG GCCCGCCGGG GTGCACCTCT CAGGCCTGCA GCCCTCGGCC 
GGCCAGTTCT TCGCATCTCT AGATCCCATT AACGAGGCTT CTGCAATCCT GAGTCCCTTA 
AACTCGAACC CAAGAAATTC AGTTCAGCAT CAGTTCCAAG ACACGTTTCC AGGTCCCTAT 
GCTGTGCTCA CGAAGGACAC CATGCCGCAG ACGTACAAAA GGAAGCGTTC ATGGTCGCGC 
GCTGTGTTCT CCAACCTGCA GAGGAAAGGC CTGGAGAAAA GGTTTGAGAT TCAGAAGTAC 
GTGACCAAGC CGGACCGAAA GCAGCTGGCG GCGATGCTGG GCCTCACGGA CGCACAGGTG 
AAGGTGTGGT TCCAGAACCG GCGGATGAAG TGGCGGCACT CCAAGGAGGC CCAGGCCCAA 
AAGGACAAGG ACAAGGAGGC TGGCGAGAAG CCATCAGGTG GAGCCCCGGC TGCGGATGGC 
GAGCAGGACG AGAGGAGCCC CAGCCGTTCT GAAGGCGAGG CTGAGAGCGA GAGCAGCGAC 
TCCGAGTCCC TGGACATGGC CCCCAGCGAC ACGGAGCGGA CTGAGGGGAG TGAGCGTTCT 
CTGCACCAAA CAACAGTTAT TAAGGCCCCG GTCACTGGCG CCCTCATTAC CGCCAGCAGT 
GCTGGGAGTG GTGGGAGCAG CGGCGGCGGC GGCAATAGTT TCAGCTTCAG CAGCGCCAGC 
AGTCTTAGTA GCAGCAGCAC CAGTGCGGGT TGCGCCAGCA GCCTTGGCGG CGGCGGCGCC 
TCGGAGCTTC TCCCTGCAAC ACAGCCCACA GCCAGCAGCG CTCCCAAAAG CCCCGAGCCA 
GCCCAAGGCG CGCTTGGCTG CTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of Homeobox Gene HLX and its Downstream Target Genes are Altered in Placentae From Discordant Twin Pregnancies.
Twin research and human genetics : the official journal of the International Society for Twin Studies1-9(2017 Dec)
Yuen N,Brennecke SP,Umstad MP,Yong HEJ,Borg AJ,Rajaraman G,Kalionis B,Murthi P

HLX is a candidate gene for a pattern of anomalies associated with congenital diaphragmatic hernia, short bowel, and asplenia.
American journal of medical genetics. Part A173(11)3070-3074(2017 Nov)
Farrell SA,Sodhi S,Marshall CR,Guerin A,Slavotinek A,Paton T,Chong K,Sirkin WL,Scherer SW,B?rub?-Simard FA,Pilon N

Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation.
Nature communications8(1)68(2017 07)
Huang L,Pan D,Chen Q,Zhu LJ,Ou J,Wabitsch M,Wang YX

Screening of Human cDNA Library Reveals Two differentiation-Related Genes, HHEX and HLX, as Promoters of Early Phase Reprogramming toward Pluripotency.
Stem cells (Dayton, Ohio)34(11)2661-2669(2016 Nov)
Yamakawa T,Sato Y,Matsumura Y,Kobayashi Y,Kawamura Y,Goshima N,Yamanaka S,Okita K

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HLX cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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