HLA-DQB2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HLA-DQB2
Entrez Gene ID	3120
Full Name	major histocompatibility complex, class II, DQ beta 2
Synonyms	HLA-DQB1,HLA-DXB
General protein information	Preferred Names major histocompatibility complex, class II, DQ beta 2 Names HLA class II histocompatibility antigen, DQ beta 2 chain DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)) HLA class II histocompatibility antigen, DX beta chain MHC class II antigen DQB2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.32
Summary	HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010].
Disorder MIM:	615161

mRNA and Protein(s)

mRNA	Protein	Name
NM_001300790.2	NP_001287719.1	HLA class II histocompatibility antigen, DQ beta 2 chain isoform 1 precursor
NM_001198858.1	NP_001185787.1	HLA class II histocompatibility antigen, DQ beta 2 chain isoform 2 precursor
XM_011514560.2	XP_011512862.1	HLA class II histocompatibility antigen, DQ beta 2 chain isoform X2
XM_011514561.3	XP_011512863.1	HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3
NM_001300790.1	NP_001287719.1	HLA class II histocompatibility antigen, DQ beta 2 chain isoform 1 precursor
XM_011514561.2	XP_011512863.1	HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3
XM_005249051.4	XP_005249108.1	HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1
NM_001198858.2	NP_001185787.1	HLA class II histocompatibility antigen, DQ beta 2 chain isoform 2 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population.
Pereira VRZB, Wolf JM, Stumm GZ, Boeira TR, Galvan J, Simon D, Lunge VR
Genetics and molecular research : GMR16(2)(2017 May)

Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.
Liu X, Yang B, Li L, Cai B, Liao Y, Li L, Wu Z, Wang L
International immunopharmacology3910-15(2016 Oct)

A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese.
Chang SW, Fann CS, Su WH, Wang YC, Weng CC, Yu CJ, Hsu CL, Hsieh AR, Chien RN, Chu CM, Tai DI
PloS one9(6)e99724(2014)

New loci associated with chronic hepatitis B virus infection in Han Chinese.
Hu Z, Liu Y, Zhai X, Dai J, Jin G, Wang L, Zhu L, Yang Y, Liu J, Chu M, Wen J, Xie K, Du G, Wang Q, Zhou Y, Cao M, Liu L, He Y, Wang Y, Zhou G, Jia W, Lu J, Li S, Liu J, Yang H, Shi Y, Zhou W, Shen H
Nature genetics45(12)1499-503(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

No statistically significant association was found between rs7453920 SNP and chronic hepatitis B.
Title: Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population.

this study shows that HLA-DQ gene polymorphisms are associated with ankylosing spondylitis in Southwest China
Title: Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.

HLA-DQA2 and HLA-DQB2 genes are expressed in human Langerhans cells and encode a new HLA class II molecule.
Title: HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule.

Data show that two peptides with naturally processed DQ8 (DQA1 *0301/DQB1 *0302) epitopes bound protective DR0403 with longer half-life and lower dissociation rate than susceptible DR0401, confirming DR0403 as a better peptide competitor than DR0401.
Title: Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes.

Observational study of gene-disease association. (HuGE Navigator)
Title: Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.

The following HLA-DQB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HLA-DQB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu58245	NM_001300790.2 Latest version!	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu20438	NM_001198858.2 Latest version!	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu40289	XM_005249051.4 Latest version!	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu58238	XM_011514560.2 Latest version!	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu58239	XM_011514561.3 Latest version!	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu58245	NM_001300790.1	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu58239	XM_011514561.2	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu20438	NM_001198858.1	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HLA-DQB2 ( NM_001300790.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001287719.1 Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu58245
Clone ID Related Accession (Same CDS sequence)	NM_001300790.2 , NM_001300790.1
Accession Version	NM_001300790.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	HLA class II histocompatibility antigen, DQ beta 2 chain isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL672104.4. On Nov 22, 2018 this sequence version replaced NM_001300790.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000437316.7/ ENSP00000396330.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA 
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC 
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA 
GGACTCCTGC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287719.1
CDS	63..857
Translation	MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIRHRGQKGPRGPPPAGLLH

Target ORF information:

RefSeq Version	NM_001300790.2
Organism	Homo sapiens(human)
Definition	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300790.2

ORF Insert Sequence:

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA 
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC 
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA 
GGACTCCTGC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLA-DQB2 ( NM_001300790.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001287719.1 Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu58245
Clone ID Related Accession (Same CDS sequence)	NM_001300790.2 , NM_001300790.1
Accession Version	NM_001300790.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-08
Organism	Homo sapiens(human)
Product	HLA class II histocompatibility antigen, DQ beta 2 chain isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672104.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA 
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC 
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA 
GGACTCCTGC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287719.1
CDS	84..878
Translation	MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIRHRGQKGPRGPPPAGLLH

Target ORF information:

RefSeq Version	NM_001300790.1
Organism	Homo sapiens(human)
Definition	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300790.1

ORF Insert Sequence:

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA 
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC 
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA 
GGACTCCTGC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLA-DQB2 ( NM_001198858.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185787.1 Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20438
Clone ID Related Accession (Same CDS sequence)	NM_001198858.1 , NM_001198858.2
Accession Version	NM_001198858.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	HLA class II histocompatibility antigen, DQ beta 2 chain isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL672104.4. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. It encodes a shorter isoform (2), compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031995.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACC TCGAGGGCCT 
CCACCAGCAG GACTCCTGCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185787.1
CDS	84..767
Translation	MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRPRGPPPAGLLH

Target ORF information:

RefSeq Version	NM_001198858.1
Organism	Homo sapiens(human)
Definition	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198858.1

ORF Insert Sequence:

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACC TCGAGGGCCT 
CCACCAGCAG GACTCCTGCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLA-DQB2 ( NM_001198858.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185787.1 Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20438
Clone ID Related Accession (Same CDS sequence)	NM_001198858.1 , NM_001198858.2
Accession Version	NM_001198858.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	HLA class II histocompatibility antigen, DQ beta 2 chain isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL672104.4. On May 31, 2019 this sequence version replaced NM_001198858.1. Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. It encodes a shorter isoform (2), compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031995.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACC TCGAGGGCCT 
CCACCAGCAG GACTCCTGCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185787.1
CDS	63..746
Translation	MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRPRGPPPAGLLH

Target ORF information:

RefSeq Version	NM_001198858.2
Organism	Homo sapiens(human)
Definition	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198858.2

ORF Insert Sequence:

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACC TCGAGGGCCT 
CCACCAGCAG GACTCCTGCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLA-DQB2 ( XM_005249051.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005249108.1 Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu40289
Clone ID Related Accession (Same CDS sequence)	XM_005249051.4
Accession Version	XM_005249051.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 828bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005249051.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA 
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC 
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA 
GGTAATATTT CAGCCATGAT CCAGTCAGGG GAGAGGGCAC AGGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005249108.1
CDS	84..911
Translation	MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIRHRGQKGPRGPPPAGNISAMIQSGERAQA

Target ORF information:

RefSeq Version	XM_005249051.4
Organism	Homo sapiens(human)
Definition	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005249051.4

ORF Insert Sequence:

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA 
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC 
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC CTCGAGGGCC TCCACCAGCA 
GGTAATATTT CAGCCATGAT CCAGTCAGGG GAGAGGGCAC AGGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLA-DQB2 ( XM_011514560.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512862.1 Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu58238
Clone ID Related Accession (Same CDS sequence)	XM_011514560.2
Accession Version	XM_011514560.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	HLA class II histocompatibility antigen, DQ beta 2 chain isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514560.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA 
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC 
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC TCCTGCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512862.1
CDS	84..854
Translation	MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIRHRGQKGLLH

Target ORF information:

RefSeq Version	XM_011514560.2
Organism	Homo sapiens(human)
Definition	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514560.2

ORF Insert Sequence:

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGGGC TCAGTCTGAA 
TCTGCCCAGA GCAAGATGCT GAGTGGCATT GGAGGCTTCG TGCTGGGGCT GATCTTCCTC 
GGGCTGGGCC TTATCATCCG TCACAGGGGT CAGAAAGGAC TCCTGCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLA-DQB2 ( XM_011514561.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512863.1 Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu58239
Clone ID Related Accession (Same CDS sequence)	XM_011514561.3 , XM_011514561.2
Accession Version	XM_011514561.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011514561.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACT CCTGCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512863.1
CDS	83..742
Translation	MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRLLH

Target ORF information:

RefSeq Version	XM_011514561.3
Organism	Homo sapiens(human)
Definition	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514561.3

ORF Insert Sequence:

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACT CCTGCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HLA-DQB2 ( XM_011514561.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512863.1 Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu58239
Clone ID Related Accession (Same CDS sequence)	XM_011514561.3 , XM_011514561.2
Accession Version	XM_011514561.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514561.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACT CCTGCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512863.1
CDS	84..743
Translation	MALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELGRSIEDWNNYKDFLEQERAAVDKVCRHNYEAELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWRLLH

Target ORF information:

RefSeq Version	XM_011514561.2
Organism	Homo sapiens(human)
Definition	Homo sapiens major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514561.2

ORF Insert Sequence:

ATGGCTCTGC AGATCCCTGG AGGCTTTTGG GCAGCAGCTG TGACCGTGAT GCTGGTGATG 
CTGAGCACCC CAGTGGCTGA GGCCAGAGAC TTTCCCAAGG ATTTCTTGGT CCAGTTTAAG 
GGCATGTGCT ACTTCACCAA CGGGACAGAG CGCGTGCGCG GTGTGGCCAG ATACATCTAT 
AACCGCGAGG AGTACGGGCG CTTCGACAGC GACGTTGGGG AGTTCCAGGC GGTGACCGAG 
CTGGGGCGGA GCATCGAGGA CTGGAACAAC TATAAGGACT TCTTGGAGCA GGAGCGGGCC 
GCGGTGGACA AGGTGTGCAG ACACAACTAC GAGGCGGAGC TGCGCACGAC CTTGCAGCGG 
CAAGTGGAGC CCACAGTGAC CATCTCCCCA TCCAGGACAG AGGCCCTCAA CCACCACAAC 
CTGCTGGTCT GCTCGGTGAC AGATTTCTAT CCAGCCCAGA TCAAAGTCCG GTGGTTTCGG 
AATGACCAGG AGGAGACAGC CGGTGTTGTG TCCACCTCCC TCATTAGGAA TGGTGACTGG 
ACCTTCCAGA TTCTGGTGAT GCTGGAAATA ACTCCCCAGC GTGGAGACAT CTACACCTGC 
CAAGTGGAGC ACCCCAGCCT CCAGAGCCCC ATCACCGTGG AGTGGCGACT CCTGCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population.
Genetics and molecular research : GMR16(2)(2017 May)
Pereira VRZB,Wolf JM,Stumm GZ,Boeira TR,Galvan J,Simon D,Lunge VR

Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.
International immunopharmacology3910-15(2016 Oct)
Liu X,Yang B,Li L,Cai B,Liao Y,Li L,Wu Z,Wang L

A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese.
PloS one9(6)e99724(2014)
Chang SW,Fann CS,Su WH,Wang YC,Weng CC,Yu CJ,Hsu CL,Hsieh AR,Chien RN,Chu CM,Tai DI

New loci associated with chronic hepatitis B virus infection in Han Chinese.
Nature genetics45(12)1499-503(2013 Dec)
Hu Z,Liu Y,Zhai X,Dai J,Jin G,Wang L,Zhu L,Yang Y,Liu J,Chu M,Wen J,Xie K,Du G,Wang Q,Zhou Y,Cao M,Liu L,He Y,Wang Y,Zhou G,Jia W,Lu J,Li S,Liu J,Yang H,Shi Y,Zhou W,Shen H

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HLA-DQB2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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