gRNAs
The following PIK3R4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PIK3R4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu06559 | |
| Clone ID Related Accession (Same CDS sequence) | NM_014602.2 , NM_014602.3 | |
| Accession Version | NM_014602.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4077bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-11-01 | |
| Organism | Homo sapiens(human) | |
| Product | phosphoinositide 3-kinase regulatory subunit 4 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP359657.1 and Y08991.1. On Oct 28, 2006 this sequence version replaced NM_014602.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y08991.1, SRR1803616.271117.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGGAAATC AGCTTGCTGG CATTGCTCCC TCCCAGATCC TTTCTGTAGA GAGTTATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_055417.1 |
| CDS | 582..4658 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_014602.2 |
1 | ATGGGAAATC AGCTTGCTGG CATTGCTCCC TCCCAGATCC TTTCTGTAGA GAGTTATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu06559 | |
| Clone ID Related Accession (Same CDS sequence) | NM_014602.2 , NM_014602.3 | |
| Accession Version | NM_014602.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4077bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-30 | |
| Organism | Homo sapiens(human) | |
| Product | phosphoinositide 3-kinase regulatory subunit 4 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP359657.1 and Y08991.1. On Nov 22, 2018 this sequence version replaced NM_014602.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y08991.1, SRR1803614.188243.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000356763.8/ ENSP00000349205.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGGGAAATC AGCTTGCTGG CATTGCTCCC TCCCAGATCC TTTCTGTAGA GAGTTATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_055417.1 |
| CDS | 559..4635 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_014602.3 |
1 | ATGGGAAATC AGCTTGCTGG CATTGCTCCC TCCCAGATCC TTTCTGTAGA GAGTTATTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. |
Architecture of the human interactome defines protein communities and disease networks. |
Autophagy dysregulation in Danon disease. |
A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi. |
High expression of PI3K core complex genes is associated with poor prognosis in chronic lymphocytic leukemia. |
