SOCS7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SOCS7
Entrez Gene ID	30837
Full Name	suppressor of cytokine signaling 7
Synonyms	NAP4,NCKAP4
General protein information	Preferred Names suppressor of cytokine signaling 7 Names suppressor of cytokine signaling 7 NAP-4 NCK-associated protein 4 Nck, Ash and phospholipase C binding protein SOCS-7 nck, Ash and phospholipase C gamma-binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q12
Disorder MIM:	608788

mRNA and Protein(s)

mRNA	Protein	Name
NM_014598.3	NP_055413.1	suppressor of cytokine signaling 7
NM_014598.4	NP_055413.2	suppressor of cytokine signaling 7
XM_017024552.1	XP_016880041.1	suppressor of cytokine signaling 7 isoform X2
XM_017024551.1	XP_016880040.1	suppressor of cytokine signaling 7 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SOCS7	NP_055413.1
Bos taurus (cattle)	SOCS7	NP_001192942.1
Gallus gallus (chicken)	SOCS7	XP_423895.4
Danio rerio (zebrafish)	LOC100538186	XP_005155820.1
Pan troglodytes (chimpanzee)	SOCS7	XP_003954482.1
Xenopus tropicalis (tropical clawed frog)	socs7	NP_001121531.1
	SOCS6	XP_001082440.2
Mus musculus (house mouse)	Socs7	NP_619598.1
Rattus norvegicus (Norway rat)	Socs7	XP_006247546.1
Danio rerio (zebrafish)	LOC100535711	XP_005174464.1
Canis lupus familiaris (dog)	SOCS7	XP_005625038.1
Danio rerio (zebrafish)	socs7	XP_005155819.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia.
Walker DG, Whetzel AM, Lue LF
Neuroscience302121-37(2015 Aug)

Observations on the effects of Suppressor of Cytokine Signaling 7 (SOCS7) knockdown in breast cancer cells: their in vitro response to Insulin Like Growth Factor I (IGF-I).
Sasi W, Ye L, Jiang WG, Mokbel K, Sharma A
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico16(5)476-87(2014 May)

In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.
Sasi W, Ye L, Jiang WG, Sharma AK, Mokbel K
BioMed research international2014648040(2014)

Polymorphisms in the SOCS7 gene and glucose homeostasis traits.
Capuano MM, Sorkin JD, Chang YP, Ling H, O'Connell JR, Rothman PB, Mitchell BD, Silver KD
BMC research notes6235(2013 Jun)

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Pharoah PD, Tsai YY, Ramus SJ, Phelan CM, Goode EL, Lawrenson K, Buckley M, Fridley BL, Tyrer JP, Shen H, Weber R, Karevan R, Larson MC, Song H, Tessier DC, Bacot F, Vincent D, Cunningham JM, Dennis J, Dicks E, , , Aben KK, Anton-Culver H, Antonenkova N, Armasu SM, Baglietto L, Bandera EV, Beckmann MW, Birrer MJ, Bloom G, Bogdanova N, Brenton JD, Brinton LA, Brooks-Wilson A, Brown R, Butzow R, Campbell I, Carney ME, Carvalho RS, Chang-Claude J, Chen YA, Chen Z, Chow WH, Cicek MS, Coetzee G, Cook LS, Cramer DW, Cybulski C, Dansonka-Mieszkowska A, Despierre E, Doherty JA, D?rk T, du Bois A, D?rst M, Eccles D, Edwards R, Ekici AB, Fasching PA, Fenstermacher D, Flanagan J, Gao YT, Garcia-Closas M, Gentry-Maharaj A, Giles G, Gjyshi A, Gore M, Gronwald J, Guo Q, Halle MK, Harter P, Hein A, Heitz F, Hillemanns P, Hoatlin M, H?gdall E, H?gdall CK, Hosono S, Jakubowska A, Jensen A, Kalli KR, Karlan BY, Kelemen LE, Kiemeney LA, Kjaer SK, Konecny GE, Krakstad C, Kupryjanczyk J, Lambrechts D, Lambrechts S, Le ND, Lee N, Lee J, Leminen A, Lim BK, Lissowska J, Lubi?ski J, Lundvall L, Lurie G, Massuger LF, Matsuo K, McGuire V, McLaughlin JR, Menon U, Modugno F, Moysich KB, Nakanishi T, Narod SA, Ness RB, Nevanlinna H, Nickels S, Noushmehr H, Odunsi K, Olson S, Orlow I, Paul J, Pejovic T, Pelttari LM, Permuth-Wey J, Pike MC, Poole EM, Qu X, Risch HA, Rodriguez-Rodriguez L, Rossing MA, Rudolph A, Runnebaum I, Rzepecka IK, Salvesen HB, Schwaab I, Severi G, Shen H, Shridhar V, Shu XO, Sieh W, Southey MC, Spellman P, Tajima K, Teo SH, Terry KL, Thompson PJ, Timorek A, Tworoger SS, van Altena AM, van den Berg D, Vergote I, Vierkant RA, Vitonis AF, Wang-Gohrke S, Wentzensen N, Whittemore AS, Wik E, Winterhoff B, Woo YL, Wu AH, Yang HP, Zheng W, Ziogas A, Zulkifli F, Goodman MT, Hall P, Easton DF, Pearce CL, Berchuck A, Chenevix-Trench G, Iversen E, Monteiro AN, Gayther SA, Schildkraut JM, Sellers TA
Nature genetics45(4)362-70, 370e1-2(2013 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study showed that increased protein levels of SOCS-4 and SOCS-7 in Alzheimer's disease brains.
Title: Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia.

Insulin Like Growth Factor I treatment and SOCS7 loss have synergistically resulted in increased growth and migration of MCF7 and in increased migration of MDA-MB-231 cells.
Title: Observations on the effects of Suppressor of Cytokine Signaling 7 (SOCS7) knockdown in breast cancer cells: their in vitro response to Insulin Like Growth Factor I (IGF-I).

This SOCS7 knockdown-attributed effect could be due to a precise anti-PLCg-1 role.
Title: In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.

genetic variants in the SOCS7 gene do not impact variation in glucose homeostasis traits and only minimally impact risk of T2DM in the Old Order Amish
Title: Polymorphisms in the SOCS7 gene and glucose homeostasis traits.

SOCS7 functioned as an oncogene, the finding that revealed a novel mechanism of carcinogenesis in bladder cancer cells.
Title: socs7, a target gene of microRNA-145, regulates interferon-? induction through STAT3 nuclear translocation in bladder cancer cells.

The following SOCS7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SOCS7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09302	NM_014598.3 Latest version!	Homo sapiens suppressor of cytokine signaling 7 (SOCS7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu107803	NM_014598.4 Latest version!	Homo sapiens suppressor of cytokine signaling 7 (SOCS7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu86813	XM_017024551.1 Latest version!	Homo sapiens suppressor of cytokine signaling 7 (SOCS7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu86814	XM_017024552.1 Latest version!	Homo sapiens suppressor of cytokine signaling 7 (SOCS7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SOCS7 ( NM_014598.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055413.1 Homo sapiens suppressor of cytokine signaling 7 (SOCS7), mRNA.

Price & Availability↑

CloneID	OHu09302
Clone ID Related Accession (Same CDS sequence)	NM_014598.3
Accession Version	NM_014598.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1746bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	suppressor of cytokine signaling 7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC244092.2, BC128607.1, AB005216.1 and AC244153.3. On Mar 12, 2014 this sequence version replaced NM_014598.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279871.4407.1, AB005216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTTCC GCAACGTGGG TCGGCCGCCG GAGGAGGAGG ACGTGGAGGC GGCCCCGGAG 
CCGGGACCCT CGGAACTGCT GTGTCCCCGG CACCGCTGTG CCCTGGACCC CAAGGCCCTG 
CCGCCGGGCT TGGCGCTCGA GCGGACCTGG GGCCCGGCGG CTGGACTAGA GGCGCAGTTG 
GCGGCTCTGG GGCTCGGGCA GCCGGCGGGG CCGGGGGTCA AGACAGTCGG TGGGGGTTGC 
TGCCCGTGTC CGTGTCCTCC TCAGCCGCCC CCTCCGCAGC CCCAGCCGCC TGCTGCCGCC 
CCGCAGGCCG GGGAGGACCC CACGGAAACG AGCGACGCGC TGCTGGTCCT GGAGGGCTTG 
GAATCGGAGG CCGAGAGCCT GGAGACTAAC AGCTGCTCGG AAGAGGAGCT CAGCAGCCCG 
GGTCGCGGAG GAGGAGGGGG CGGCCGGCTT CTGCTGCAGC CCCCAGGCCC TGAATTACCT 
CCGGTGCCCT TCCCGCTGCA GGACTTGGTC CCTCTGGGGC GCCTGAGTAG AGGGGAGCAG 
CAGCAGCAGC AGCAGCAGCA ACCTCCCCCG CCCCCGCCTC CTCCCGGGCC CCTCCGGCCA 
CTCGCGGGTC CTTCTCGGAA GGGCTCCTTC AAAATCCGCC TCAGTCGCCT CTTTCGCACC 
AAGAGCTGCA ACGGTGGCTC CGGCGGTGGG GATGGGACCG GCAAGAGGCC TTCTGGAGAG 
CTGGCTGCTT CAGCTGCGAG CCTGACAGAC ATGGGAGGCT CTGCGGGCCG GGAGCTGGAC 
GCGGGGAGGA AACCCAAGTT GACAAGAACT CAAAGTGCCT TTTCTCCGGT CTCCTTCAGC 
CCCCTGTTCA CAGGTGAAAC TGTGTCGCTT GTGGATGTGG ACATTTCTCA GCGGGGCCTG 
ACCTCTCCAC ACCCTCCAAC TCCCCCTCCT CCTCCGAGAA GAAGCCTCAG CCTCCTAGAT 
GATATCAGTG GGACGCTGCC TACATCTGTC CTTGTGGCTC CGATGGGGTC TTCCTTGCAG 
TCTTTCCCCC TACCTCCGCC TCCTCCACCC CATGCCCCAG ATGCATTTCC CCGGATTGCT 
CCCATCCGAG CAGCTGAATC CCTGCACAGC CAACCCCCAC AGCACCTCCA GTGTCCCCTC 
TACCGGCCTG ACTCGAGCAG CTTTGCAGCC AGCCTTCGAG AGTTGGAGAA GTGTGGTTGG 
TATTGGGGGC CAATGAATTG GGAAGATGCA GAGATGAAGC TGAAAGGGAA ACCAGATGGT 
TCTTTCCTGG TACGAGACAG TTCTGATCCT CGTTACATCC TGAGCCTCAG TTTCCGATCA 
CAGGGTATCA CCCACCACAC TAGAATGGAG CACTACAGAG GAACCTTCAG CCTGTGGTGT 
CATCCCAAGT TTGAGGACCG CTGTCAATCT GTTGTAGAGT TTATTAAGAG AGCCATTATG 
CACTCCAAGA ATGGAAAGTT TCTCTATTTC TTAAGATCCA GGGTTCCAGG ACTGCCACCA 
ACTCCTGTCC AGCTGCTCTA TCCAGTGTCC CGATTCAGCA ATGTCAAATC CCTCCAGCAC 
CTTTGCAGAT TCCGGATACG ACAGCTCGTC AGGATAGATC ACATCCCAGA TCTCCCACTG 
CCTAAACCTC TGATCTCTTA TATCCGAAAG TTCTACTACT ATGATCCTCA GGAAGAGGTA 
TACCTGTCTC TAAAGGAAGC GCAGCTCATT TCCAAACAGA AGCAAGAGGT GGAACCCTCC 
ACGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055413.1
CDS	122..1867
Translation	MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST

Target ORF information:

RefSeq Version	NM_014598.3
Organism	Homo sapiens(human)
Definition	Homo sapiens suppressor of cytokine signaling 7 (SOCS7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014598.3

ORF Insert Sequence:

ATGGTGTTCC GCAACGTGGG TCGGCCGCCG GAGGAGGAGG ACGTGGAGGC GGCCCCGGAG 
CCGGGACCCT CGGAACTGCT GTGTCCCCGG CACCGCTGTG CCCTGGACCC CAAGGCCCTG 
CCGCCGGGCT TGGCGCTCGA GCGGACCTGG GGCCCGGCGG CTGGACTAGA GGCGCAGTTG 
GCGGCTCTGG GGCTCGGGCA GCCGGCGGGG CCGGGGGTCA AGACAGTCGG TGGGGGTTGC 
TGCCCGTGTC CGTGTCCTCC TCAGCCGCCC CCTCCGCAGC CCCAGCCGCC TGCTGCCGCC 
CCGCAGGCCG GGGAGGACCC CACGGAAACG AGCGACGCGC TGCTGGTCCT GGAGGGCTTG 
GAATCGGAGG CCGAGAGCCT GGAGACTAAC AGCTGCTCGG AAGAGGAGCT CAGCAGCCCG 
GGTCGCGGAG GAGGAGGGGG CGGCCGGCTT CTGCTGCAGC CCCCAGGCCC TGAATTACCT 
CCGGTGCCCT TCCCGCTGCA GGACTTGGTC CCTCTGGGGC GCCTGAGTAG AGGGGAGCAG 
CAGCAGCAGC AGCAGCAGCA ACCTCCCCCG CCCCCGCCTC CTCCCGGGCC CCTCCGGCCA 
CTCGCGGGTC CTTCTCGGAA GGGCTCCTTC AAAATCCGCC TCAGTCGCCT CTTTCGCACC 
AAGAGCTGCA ACGGTGGCTC CGGCGGTGGG GATGGGACCG GCAAGAGGCC TTCTGGAGAG 
CTGGCTGCTT CAGCTGCGAG CCTGACAGAC ATGGGAGGCT CTGCGGGCCG GGAGCTGGAC 
GCGGGGAGGA AACCCAAGTT GACAAGAACT CAAAGTGCCT TTTCTCCGGT CTCCTTCAGC 
CCCCTGTTCA CAGGTGAAAC TGTGTCGCTT GTGGATGTGG ACATTTCTCA GCGGGGCCTG 
ACCTCTCCAC ACCCTCCAAC TCCCCCTCCT CCTCCGAGAA GAAGCCTCAG CCTCCTAGAT 
GATATCAGTG GGACGCTGCC TACATCTGTC CTTGTGGCTC CGATGGGGTC TTCCTTGCAG 
TCTTTCCCCC TACCTCCGCC TCCTCCACCC CATGCCCCAG ATGCATTTCC CCGGATTGCT 
CCCATCCGAG CAGCTGAATC CCTGCACAGC CAACCCCCAC AGCACCTCCA GTGTCCCCTC 
TACCGGCCTG ACTCGAGCAG CTTTGCAGCC AGCCTTCGAG AGTTGGAGAA GTGTGGTTGG 
TATTGGGGGC CAATGAATTG GGAAGATGCA GAGATGAAGC TGAAAGGGAA ACCAGATGGT 
TCTTTCCTGG TACGAGACAG TTCTGATCCT CGTTACATCC TGAGCCTCAG TTTCCGATCA 
CAGGGTATCA CCCACCACAC TAGAATGGAG CACTACAGAG GAACCTTCAG CCTGTGGTGT 
CATCCCAAGT TTGAGGACCG CTGTCAATCT GTTGTAGAGT TTATTAAGAG AGCCATTATG 
CACTCCAAGA ATGGAAAGTT TCTCTATTTC TTAAGATCCA GGGTTCCAGG ACTGCCACCA 
ACTCCTGTCC AGCTGCTCTA TCCAGTGTCC CGATTCAGCA ATGTCAAATC CCTCCAGCAC 
CTTTGCAGAT TCCGGATACG ACAGCTCGTC AGGATAGATC ACATCCCAGA TCTCCCACTG 
CCTAAACCTC TGATCTCTTA TATCCGAAAG TTCTACTACT ATGATCCTCA GGAAGAGGTA 
TACCTGTCTC TAAAGGAAGC GCAGCTCATT TCCAAACAGA AGCAAGAGGT GGAACCCTCC 
ACGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SOCS7 ( NM_014598.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055413.2 Homo sapiens suppressor of cytokine signaling 7 (SOCS7), mRNA.

Price & Availability↑

CloneID	OHu107803
Clone ID Related Accession (Same CDS sequence)	NM_014598.4
Accession Version	NM_014598.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1938bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	suppressor of cytokine signaling 7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC244092.2, BC128607.1, AB005216.1 and AC244153.3. On Nov 29, 2018 this sequence version replaced NM_014598.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: The coding region has been updated to extend the N-terminus and this extension is supported by conservation data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279871.4407.1, SRR3476690.868198.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000612932.6/ ENSP00000482229.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAGGAGG CCGAGCTCCG GGATGGCGAG GCGGCGGCGG CGGCCGCTTC GTACCGCGTC 
CTGAGCCGCC TCCTTGGCTA TGGAGAGGCG GCCCCCGAGC CAGGCCCTCC GCCACCGCCC 
CCGGGCCATG GCCCCCCGCC GCCACCCTTC CTCGCGCGGC CCGGCCCGCG GGGCTCCCGG 
CCGCCGCAGC TGATGGTGTT CCGCAACGTG GGTCGGCCGC CGGAGGAGGA GGACGTGGAG 
GCGGCCCCGG AGCCGGGACC CTCGGAACTG CTGTGTCCCC GGCACCGCTG TGCCCTGGAC 
CCCAAGGCCC TGCCGCCGGG CTTGGCGCTC GAGCGGACCT GGGGCCCGGC GGCTGGACTA 
GAGGCGCAGT TGGCGGCTCT GGGGCTCGGG CAGCCGGCGG GGCCGGGGGT CAAGACAGTC 
GGTGGGGGTT GCTGCCCGTG TCCGTGTCCT CCTCAGCCGC CCCCTCCGCA GCCCCAGCCG 
CCTGCTGCCG CCCCGCAGGC CGGGGAGGAC CCCACGGAAA CGAGCGACGC GCTGCTGGTC 
CTGGAGGGCT TGGAATCGGA GGCCGAGAGC CTGGAGACTA ACAGCTGCTC GGAAGAGGAG 
CTCAGCAGCC CGGGTCGCGG AGGAGGAGGG GGCGGCCGGC TTCTGCTGCA GCCCCCAGGC 
CCTGAATTAC CTCCGGTGCC CTTCCCGCTG CAGGACTTGG TCCCTCTGGG GCGCCTGAGT 
AGAGGGGAGC AGCAGCAGCA GCAGCAGCAG CAACCTCCCC CGCCCCCGCC TCCTCCCGGG 
CCCCTCCGGC CACTCGCGGG TCCTTCTCGG AAGGGCTCCT TCAAAATCCG CCTCAGTCGC 
CTCTTTCGCA CCAAGAGCTG CAACGGTGGC TCCGGCGGTG GGGATGGGAC CGGCAAGAGG 
CCTTCTGGAG AGCTGGCTGC TTCAGCTGCG AGCCTGACAG ACATGGGAGG CTCTGCGGGC 
CGGGAGCTGG ACGCGGGGAG GAAACCCAAG TTGACAAGAA CTCAAAGTGC CTTTTCTCCG 
GTCTCCTTCA GCCCCCTGTT CACAGGTGAA ACTGTGTCGC TTGTGGATGT GGACATTTCT 
CAGCGGGGCC TGACCTCTCC ACACCCTCCA ACTCCCCCTC CTCCTCCGAG AAGAAGCCTC 
AGCCTCCTAG ATGATATCAG TGGGACGCTG CCTACATCTG TCCTTGTGGC TCCGATGGGG 
TCTTCCTTGC AGTCTTTCCC CCTACCTCCG CCTCCTCCAC CCCATGCCCC AGATGCATTT 
CCCCGGATTG CTCCCATCCG AGCAGCTGAA TCCCTGCACA GCCAACCCCC ACAGCACCTC 
CAGTGTCCCC TCTACCGGCC TGACTCGAGC AGCTTTGCAG CCAGCCTTCG AGAGTTGGAG 
AAGTGTGGTT GGTATTGGGG GCCAATGAAT TGGGAAGATG CAGAGATGAA GCTGAAAGGG 
AAACCAGATG GTTCTTTCCT GGTACGAGAC AGTTCTGATC CTCGTTACAT CCTGAGCCTC 
AGTTTCCGAT CACAGGGTAT CACCCACCAC ACTAGAATGG AGCACTACAG AGGAACCTTC 
AGCCTGTGGT GTCATCCCAA GTTTGAGGAC CGCTGTCAAT CTGTTGTAGA GTTTATTAAG 
AGAGCCATTA TGCACTCCAA GAATGGAAAG TTTCTCTATT TCTTAAGATC CAGGGTTCCA 
GGACTGCCAC CAACTCCTGT CCAGCTGCTC TATCCAGTGT CCCGATTCAG CAATGTCAAA 
TCCCTCCAGC ACCTTTGCAG ATTCCGGATA CGACAGCTCG TCAGGATAGA TCACATCCCA 
GATCTCCCAC TGCCTAAACC TCTGATCTCT TATATCCGAA AGTTCTACTA CTATGATCCT 
CAGGAAGAGG TATACCTGTC TCTAAAGGAA GCGCAGCTCA TTTCCAAACA GAAGCAAGAG 
GTGGAACCCT CCACGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055413.2
CDS	210..2147
Translation	MQEAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPPPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST

Target ORF information:

RefSeq Version	NM_014598.4
Organism	Homo sapiens(human)
Definition	Homo sapiens suppressor of cytokine signaling 7 (SOCS7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014598.4

ORF Insert Sequence:

ATGCAGGAGG CCGAGCTCCG GGATGGCGAG GCGGCGGCGG CGGCCGCTTC GTACCGCGTC 
CTGAGCCGCC TCCTTGGCTA TGGAGAGGCG GCCCCCGAGC CAGGCCCTCC GCCACCGCCC 
CCGGGCCATG GCCCCCCGCC GCCACCCTTC CTCGCGCGGC CCGGCCCGCG GGGCTCCCGG 
CCGCCGCAGC TGATGGTGTT CCGCAACGTG GGTCGGCCGC CGGAGGAGGA GGACGTGGAG 
GCGGCCCCGG AGCCGGGACC CTCGGAACTG CTGTGTCCCC GGCACCGCTG TGCCCTGGAC 
CCCAAGGCCC TGCCGCCGGG CTTGGCGCTC GAGCGGACCT GGGGCCCGGC GGCTGGACTA 
GAGGCGCAGT TGGCGGCTCT GGGGCTCGGG CAGCCGGCGG GGCCGGGGGT CAAGACAGTC 
GGTGGGGGTT GCTGCCCGTG TCCGTGTCCT CCTCAGCCGC CCCCTCCGCA GCCCCAGCCG 
CCTGCTGCCG CCCCGCAGGC CGGGGAGGAC CCCACGGAAA CGAGCGACGC GCTGCTGGTC 
CTGGAGGGCT TGGAATCGGA GGCCGAGAGC CTGGAGACTA ACAGCTGCTC GGAAGAGGAG 
CTCAGCAGCC CGGGTCGCGG AGGAGGAGGG GGCGGCCGGC TTCTGCTGCA GCCCCCAGGC 
CCTGAATTAC CTCCGGTGCC CTTCCCGCTG CAGGACTTGG TCCCTCTGGG GCGCCTGAGT 
AGAGGGGAGC AGCAGCAGCA GCAGCAGCAG CAACCTCCCC CGCCCCCGCC TCCTCCCGGG 
CCCCTCCGGC CACTCGCGGG TCCTTCTCGG AAGGGCTCCT TCAAAATCCG CCTCAGTCGC 
CTCTTTCGCA CCAAGAGCTG CAACGGTGGC TCCGGCGGTG GGGATGGGAC CGGCAAGAGG 
CCTTCTGGAG AGCTGGCTGC TTCAGCTGCG AGCCTGACAG ACATGGGAGG CTCTGCGGGC 
CGGGAGCTGG ACGCGGGGAG GAAACCCAAG TTGACAAGAA CTCAAAGTGC CTTTTCTCCG 
GTCTCCTTCA GCCCCCTGTT CACAGGTGAA ACTGTGTCGC TTGTGGATGT GGACATTTCT 
CAGCGGGGCC TGACCTCTCC ACACCCTCCA ACTCCCCCTC CTCCTCCGAG AAGAAGCCTC 
AGCCTCCTAG ATGATATCAG TGGGACGCTG CCTACATCTG TCCTTGTGGC TCCGATGGGG 
TCTTCCTTGC AGTCTTTCCC CCTACCTCCG CCTCCTCCAC CCCATGCCCC AGATGCATTT 
CCCCGGATTG CTCCCATCCG AGCAGCTGAA TCCCTGCACA GCCAACCCCC ACAGCACCTC 
CAGTGTCCCC TCTACCGGCC TGACTCGAGC AGCTTTGCAG CCAGCCTTCG AGAGTTGGAG 
AAGTGTGGTT GGTATTGGGG GCCAATGAAT TGGGAAGATG CAGAGATGAA GCTGAAAGGG 
AAACCAGATG GTTCTTTCCT GGTACGAGAC AGTTCTGATC CTCGTTACAT CCTGAGCCTC 
AGTTTCCGAT CACAGGGTAT CACCCACCAC ACTAGAATGG AGCACTACAG AGGAACCTTC 
AGCCTGTGGT GTCATCCCAA GTTTGAGGAC CGCTGTCAAT CTGTTGTAGA GTTTATTAAG 
AGAGCCATTA TGCACTCCAA GAATGGAAAG TTTCTCTATT TCTTAAGATC CAGGGTTCCA 
GGACTGCCAC CAACTCCTGT CCAGCTGCTC TATCCAGTGT CCCGATTCAG CAATGTCAAA 
TCCCTCCAGC ACCTTTGCAG ATTCCGGATA CGACAGCTCG TCAGGATAGA TCACATCCCA 
GATCTCCCAC TGCCTAAACC TCTGATCTCT TATATCCGAA AGTTCTACTA CTATGATCCT 
CAGGAAGAGG TATACCTGTC TCTAAAGGAA GCGCAGCTCA TTTCCAAACA GAAGCAAGAG 
GTGGAACCCT CCACGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SOCS7 ( XM_017024551.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016880040.1 Homo sapiens suppressor of cytokine signaling 7 (SOCS7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu86813
Clone ID Related Accession (Same CDS sequence)	XM_017024551.1
Accession Version	XM_017024551.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	suppressor of cytokine signaling 7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGAGG CCGAGCTCCG GGATGGCGAG GCGGCGGCGG CGGCCGCTTC GTACCGCGTC 
CTGAGCCGCC TCCTTGGCTA TGGAGAGGCG GCCCCCGAGC CAGGCCCTCC GCCACCGCCC 
CCGGGCCATG GCCCCCCGCC GCCACCCTTC CTCGCGCGGC CCGGCCCGCG GGGCTCCCGG 
CCGCCGCAGC TGATGGTGTT CCGCAACGTG GGTCGGCCGC CGGAGGAGGA GGACGTGGAG 
GCGGCCCCGG AGCCGGGACC CTCGGAACTG CTGTGTCCCC GGCACCGCTG TGCCCTGGAC 
CCCAAGGCCC TGCCGCCGGG CTTGGCGCTC GAGCGGACCT GGGGCCCGGC GGCTGGACTA 
GAGGCGCAGT TGGCGGCTCT GGGGCTCGGG CAGCCGGCGG GGCCGGGGGT CAAGACAGTC 
GGTGGGGGTT GCTGCCCGTG TCCGTGTCCT CCTCAGCCGC CCCCTCCGCA GCCCCAGCCG 
CCTGCTGCCG CCCCGCAGGC CGGGGAGGAC CCCACGGAAA CGAGCGACGC GCTGCTGGTC 
CTGGAGGGCT TGGAATCGGA GGCCGAGAGC CTGGAGACTA ACAGCTGCTC GGAAGAGGAG 
CTCAGCAGCC CGGGTCGCGG AGGAGGAGGG GGCGGCCGGC TTCTGCTGCA GCCCCCAGGC 
CCTGAATTAC CTCCGGTGCC CTTCCCGCTG CAGGACTTGG TCCCTCTGGG GCGCCTGAGT 
AGAGGGGAGC AGCAGCAGCA GCAGCAGCAG CAACCTCCCC CGCCCCCGCC TCCTCCCGGG 
CCCCTCCGGC CACTCGCGGG TCCTTCTCGG AAGGGCTCCT TCAAAATCCG CCTCAGTCGC 
CTCTTTCGCA CCAAGAGCTG CAACGGTGGC TCCGGCGGTG GGGATGGGAC CGGCAAGAGG 
CCTTCTGGAG AGCTGGCTGC TTCAGCTGCG AGCCTGACAG ACATGGGAGG CTCTGCGGGC 
CGGGAGCTGG ACGCGGGGAG GAAACCCAAG TTGACAAGAA CTCAAAGTGC CTTTTCTCCG 
GTCTCCTTCA GCCCCCTGTT CACAGGTGAA ACTGTGTCGC TTGTGGATGT GGACATTTCT 
CAGCGGGGCC TGACCTCTCC ACACCCTCCA ACTCCCCCTC CTCCTCCGAG AAGAAGCCTC 
AGCCTCCTAG ATGCATTTCC CCGGATTGCT CCCATCCGAG CAGCTGAATC CCTGCACAGC 
CAACCCCCAC AGCACCTCCA GTGTCCCCTC TACCGGCCTG ACTCGAGCAG CTTTGCAGCC 
AGCCTTCGAG AGTTGGAGAA GTGTGGTTGG TATTGGGGGC CAATGAATTG GGAAGATGCA 
GAGATGAAGC TGAAAGGGAA ACCAGATGGT TCTTTCCTGG TACGAGACAG TTCTGATCCT 
CGTTACATCC TGAGCCTCAG TTTCCGATCA CAGGGTATCA CCCACCACAC TAGAATGGAG 
CACTACAGAG GAACCTTCAG CCTGTGGTGT CATCCCAAGT TTGAGGACCG CTGTCAATCT 
GTTGTAGAGT TTATTAAGAG AGCCATTATG CACTCCAAGA ATGGAAAGTT TCTCTATTTC 
TTAAGATCCA GGGTTCCAGG ACTGCCACCA ACTCCTGTCC AGCTGCTCTA TCCAGTGTCC 
CGATTCAGCA ATGTCAAATC CCTCCAGCAC CTTTGCAGAT TCCGGATACG ACAGCTCGTC 
AGGATAGATC ACATCCCAGA TCTCCCACTG CCTAAACCTC TGATCTCTTA TATCCGAAAG 
TTCTACTACT ATGATCCTCA GGAAGAGGTA TACCTGTCTC TAAAGGAAGC GCAGCTCATT 
TCCAAACAGA AGCAAGAGGT GGAACCCTCC ACGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016880040.1
CDS	178..2013
Translation	MQEAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPPPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST

Target ORF information:

RefSeq Version	XM_017024551.1
Organism	Homo sapiens(human)
Definition	Homo sapiens suppressor of cytokine signaling 7 (SOCS7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017024551.1

ORF Insert Sequence:

ATGCAGGAGG CCGAGCTCCG GGATGGCGAG GCGGCGGCGG CGGCCGCTTC GTACCGCGTC 
CTGAGCCGCC TCCTTGGCTA TGGAGAGGCG GCCCCCGAGC CAGGCCCTCC GCCACCGCCC 
CCGGGCCATG GCCCCCCGCC GCCACCCTTC CTCGCGCGGC CCGGCCCGCG GGGCTCCCGG 
CCGCCGCAGC TGATGGTGTT CCGCAACGTG GGTCGGCCGC CGGAGGAGGA GGACGTGGAG 
GCGGCCCCGG AGCCGGGACC CTCGGAACTG CTGTGTCCCC GGCACCGCTG TGCCCTGGAC 
CCCAAGGCCC TGCCGCCGGG CTTGGCGCTC GAGCGGACCT GGGGCCCGGC GGCTGGACTA 
GAGGCGCAGT TGGCGGCTCT GGGGCTCGGG CAGCCGGCGG GGCCGGGGGT CAAGACAGTC 
GGTGGGGGTT GCTGCCCGTG TCCGTGTCCT CCTCAGCCGC CCCCTCCGCA GCCCCAGCCG 
CCTGCTGCCG CCCCGCAGGC CGGGGAGGAC CCCACGGAAA CGAGCGACGC GCTGCTGGTC 
CTGGAGGGCT TGGAATCGGA GGCCGAGAGC CTGGAGACTA ACAGCTGCTC GGAAGAGGAG 
CTCAGCAGCC CGGGTCGCGG AGGAGGAGGG GGCGGCCGGC TTCTGCTGCA GCCCCCAGGC 
CCTGAATTAC CTCCGGTGCC CTTCCCGCTG CAGGACTTGG TCCCTCTGGG GCGCCTGAGT 
AGAGGGGAGC AGCAGCAGCA GCAGCAGCAG CAACCTCCCC CGCCCCCGCC TCCTCCCGGG 
CCCCTCCGGC CACTCGCGGG TCCTTCTCGG AAGGGCTCCT TCAAAATCCG CCTCAGTCGC 
CTCTTTCGCA CCAAGAGCTG CAACGGTGGC TCCGGCGGTG GGGATGGGAC CGGCAAGAGG 
CCTTCTGGAG AGCTGGCTGC TTCAGCTGCG AGCCTGACAG ACATGGGAGG CTCTGCGGGC 
CGGGAGCTGG ACGCGGGGAG GAAACCCAAG TTGACAAGAA CTCAAAGTGC CTTTTCTCCG 
GTCTCCTTCA GCCCCCTGTT CACAGGTGAA ACTGTGTCGC TTGTGGATGT GGACATTTCT 
CAGCGGGGCC TGACCTCTCC ACACCCTCCA ACTCCCCCTC CTCCTCCGAG AAGAAGCCTC 
AGCCTCCTAG ATGCATTTCC CCGGATTGCT CCCATCCGAG CAGCTGAATC CCTGCACAGC 
CAACCCCCAC AGCACCTCCA GTGTCCCCTC TACCGGCCTG ACTCGAGCAG CTTTGCAGCC 
AGCCTTCGAG AGTTGGAGAA GTGTGGTTGG TATTGGGGGC CAATGAATTG GGAAGATGCA 
GAGATGAAGC TGAAAGGGAA ACCAGATGGT TCTTTCCTGG TACGAGACAG TTCTGATCCT 
CGTTACATCC TGAGCCTCAG TTTCCGATCA CAGGGTATCA CCCACCACAC TAGAATGGAG 
CACTACAGAG GAACCTTCAG CCTGTGGTGT CATCCCAAGT TTGAGGACCG CTGTCAATCT 
GTTGTAGAGT TTATTAAGAG AGCCATTATG CACTCCAAGA ATGGAAAGTT TCTCTATTTC 
TTAAGATCCA GGGTTCCAGG ACTGCCACCA ACTCCTGTCC AGCTGCTCTA TCCAGTGTCC 
CGATTCAGCA ATGTCAAATC CCTCCAGCAC CTTTGCAGAT TCCGGATACG ACAGCTCGTC 
AGGATAGATC ACATCCCAGA TCTCCCACTG CCTAAACCTC TGATCTCTTA TATCCGAAAG 
TTCTACTACT ATGATCCTCA GGAAGAGGTA TACCTGTCTC TAAAGGAAGC GCAGCTCATT 
TCCAAACAGA AGCAAGAGGT GGAACCCTCC ACGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SOCS7 ( XM_017024552.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016880041.1 Homo sapiens suppressor of cytokine signaling 7 (SOCS7), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu86814
Clone ID Related Accession (Same CDS sequence)	XM_017024552.1
Accession Version	XM_017024552.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1731bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	suppressor of cytokine signaling 7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGAGG CCGAGCTCCG GGATGGCGAG GCGGCGGCGG CGGCCGCTTC GTACCGCGTC 
CTGAGCCGCC TCCTTGGCTA TGGAGAGGCG GCCCCCGAGC CAGGCCCTCC GCCACCGCCC 
CCGGGCCATG GCCCCCCGCC GCCACCCTTC CTCGCGCGGC CCGGCCCGCG GGGCTCCCGG 
CCGCCGCAGC TGATGGTGTT CCGCAACGTG GGTCGGCCGC CGGAGGAGGA GGACGTGGAG 
GCGGCCCCGG AGCCGGGACC CTCGGAACTG CTGTGTCCCC GGCACCGCTG TGCCCTGGAC 
CCCAAGGCCC TGCCGCCGGG CTTGGCGCTC GAGCGGACCT GGGGCCCGGC GGCTGGACTA 
GAGGCGCAGT TGGCGGCTCT GGGGCTCGGG CAGCCGGCGG GGCCGGGGGT CAAGACAGTC 
GGTGGGGGTT GCTGCCCGTG TCCGTGTCCT CCTCAGCCGC CCCCTCCGCA GCCCCAGCCG 
CCTGCTGCCG CCCCGCAGGC CGGGGAGGAC CCCACGGAAA CGAGCGACGC GCTGCTGGTC 
CTGGAGGGCT TGGAATCGGA GGCCGAGAGC CTGGAGACTA ACAGCTGCTC GGAAGAGGAG 
CTCAGCAGCC CGGGTCGCGG AGGAGGAGGG GGCGGCCGGC TTCTGCTGCA GCCCCCAGGC 
CCTGAATTAC CTCCGGTGCC CTTCCCGCTG CAGGACTTGG TCCCTCTGGG GCGCCTGAGT 
AGAGGGGAGC AGCAGCAGCA GCAGCAGCAG CAACCTCCCC CGCCCCCGCC TCCTCCCGGG 
CCCCTCCGGC CACTCGCGGG TCCTTCTCGG AAGGGCTCCT TCAAAATCCG CCTCAGTCGC 
CTCTTTCGCA CCAAGAGCTG CAACGGTGGC TCCGGCGGTG GGGATGGGAC CGGCAAGAGG 
CCTTCTGGAG AGCTGGCTGC TTCAGCTGCG AGCCTGACAG ACATGGGAGG CTCTGCGGGC 
CGGGAGCTGG ACGCGGGGAG GAAACCCAAG TTGACAAGAA CTCAAAGTGC CTTTTCTCCG 
GTCTCCTTCA GCCCCCTGTT CACAGATGCA TTTCCCCGGA TTGCTCCCAT CCGAGCAGCT 
GAATCCCTGC ACAGCCAACC CCCACAGCAC CTCCAGTGTC CCCTCTACCG GCCTGACTCG 
AGCAGCTTTG CAGCCAGCCT TCGAGAGTTG GAGAAGTGTG GTTGGTATTG GGGGCCAATG 
AATTGGGAAG ATGCAGAGAT GAAGCTGAAA GGGAAACCAG ATGGTTCTTT CCTGGTACGA 
GACAGTTCTG ATCCTCGTTA CATCCTGAGC CTCAGTTTCC GATCACAGGG TATCACCCAC 
CACACTAGAA TGGAGCACTA CAGAGGAACC TTCAGCCTGT GGTGTCATCC CAAGTTTGAG 
GACCGCTGTC AATCTGTTGT AGAGTTTATT AAGAGAGCCA TTATGCACTC CAAGAATGGA 
AAGTTTCTCT ATTTCTTAAG ATCCAGGGTT CCAGGACTGC CACCAACTCC TGTCCAGCTG 
CTCTATCCAG TGTCCCGATT CAGCAATGTC AAATCCCTCC AGCACCTTTG CAGATTCCGG 
ATACGACAGC TCGTCAGGAT AGATCACATC CCAGATCTCC CACTGCCTAA ACCTCTGATC 
TCTTATATCC GAAAGTTCTA CTACTATGAT CCTCAGGAAG AGGTATACCT GTCTCTAAAG 
GAAGCGCAGC TCATTTCCAA ACAGAAGCAA GAGGTGGAAC CCTCCACGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016880041.1
CDS	178..1908
Translation	MQEAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPPPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST

Target ORF information:

RefSeq Version	XM_017024552.1
Organism	Homo sapiens(human)
Definition	Homo sapiens suppressor of cytokine signaling 7 (SOCS7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017024552.1

ORF Insert Sequence:

ATGCAGGAGG CCGAGCTCCG GGATGGCGAG GCGGCGGCGG CGGCCGCTTC GTACCGCGTC 
CTGAGCCGCC TCCTTGGCTA TGGAGAGGCG GCCCCCGAGC CAGGCCCTCC GCCACCGCCC 
CCGGGCCATG GCCCCCCGCC GCCACCCTTC CTCGCGCGGC CCGGCCCGCG GGGCTCCCGG 
CCGCCGCAGC TGATGGTGTT CCGCAACGTG GGTCGGCCGC CGGAGGAGGA GGACGTGGAG 
GCGGCCCCGG AGCCGGGACC CTCGGAACTG CTGTGTCCCC GGCACCGCTG TGCCCTGGAC 
CCCAAGGCCC TGCCGCCGGG CTTGGCGCTC GAGCGGACCT GGGGCCCGGC GGCTGGACTA 
GAGGCGCAGT TGGCGGCTCT GGGGCTCGGG CAGCCGGCGG GGCCGGGGGT CAAGACAGTC 
GGTGGGGGTT GCTGCCCGTG TCCGTGTCCT CCTCAGCCGC CCCCTCCGCA GCCCCAGCCG 
CCTGCTGCCG CCCCGCAGGC CGGGGAGGAC CCCACGGAAA CGAGCGACGC GCTGCTGGTC 
CTGGAGGGCT TGGAATCGGA GGCCGAGAGC CTGGAGACTA ACAGCTGCTC GGAAGAGGAG 
CTCAGCAGCC CGGGTCGCGG AGGAGGAGGG GGCGGCCGGC TTCTGCTGCA GCCCCCAGGC 
CCTGAATTAC CTCCGGTGCC CTTCCCGCTG CAGGACTTGG TCCCTCTGGG GCGCCTGAGT 
AGAGGGGAGC AGCAGCAGCA GCAGCAGCAG CAACCTCCCC CGCCCCCGCC TCCTCCCGGG 
CCCCTCCGGC CACTCGCGGG TCCTTCTCGG AAGGGCTCCT TCAAAATCCG CCTCAGTCGC 
CTCTTTCGCA CCAAGAGCTG CAACGGTGGC TCCGGCGGTG GGGATGGGAC CGGCAAGAGG 
CCTTCTGGAG AGCTGGCTGC TTCAGCTGCG AGCCTGACAG ACATGGGAGG CTCTGCGGGC 
CGGGAGCTGG ACGCGGGGAG GAAACCCAAG TTGACAAGAA CTCAAAGTGC CTTTTCTCCG 
GTCTCCTTCA GCCCCCTGTT CACAGATGCA TTTCCCCGGA TTGCTCCCAT CCGAGCAGCT 
GAATCCCTGC ACAGCCAACC CCCACAGCAC CTCCAGTGTC CCCTCTACCG GCCTGACTCG 
AGCAGCTTTG CAGCCAGCCT TCGAGAGTTG GAGAAGTGTG GTTGGTATTG GGGGCCAATG 
AATTGGGAAG ATGCAGAGAT GAAGCTGAAA GGGAAACCAG ATGGTTCTTT CCTGGTACGA 
GACAGTTCTG ATCCTCGTTA CATCCTGAGC CTCAGTTTCC GATCACAGGG TATCACCCAC 
CACACTAGAA TGGAGCACTA CAGAGGAACC TTCAGCCTGT GGTGTCATCC CAAGTTTGAG 
GACCGCTGTC AATCTGTTGT AGAGTTTATT AAGAGAGCCA TTATGCACTC CAAGAATGGA 
AAGTTTCTCT ATTTCTTAAG ATCCAGGGTT CCAGGACTGC CACCAACTCC TGTCCAGCTG 
CTCTATCCAG TGTCCCGATT CAGCAATGTC AAATCCCTCC AGCACCTTTG CAGATTCCGG 
ATACGACAGC TCGTCAGGAT AGATCACATC CCAGATCTCC CACTGCCTAA ACCTCTGATC 
TCTTATATCC GAAAGTTCTA CTACTATGAT CCTCAGGAAG AGGTATACCT GTCTCTAAAG 
GAAGCGCAGC TCATTTCCAA ACAGAAGCAA GAGGTGGAAC CCTCCACGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia.
Neuroscience302121-37(2015 Aug)
Walker DG,Whetzel AM,Lue LF

Observations on the effects of Suppressor of Cytokine Signaling 7 (SOCS7) knockdown in breast cancer cells: their in vitro response to Insulin Like Growth Factor I (IGF-I).
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico16(5)476-87(2014 May)
Sasi W,Ye L,Jiang WG,Mokbel K,Sharma A

In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.
BioMed research international2014648040(2014)
Sasi W,Ye L,Jiang WG,Sharma AK,Mokbel K

Polymorphisms in the SOCS7 gene and glucose homeostasis traits.
BMC research notes6235(2013 Jun)
Capuano MM,Sorkin JD,Chang YP,Ling H,O'Connell JR,Rothman PB,Mitchell BD,Silver KD

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Nature genetics45(4)362-70, 370e1-2(2013 Apr)
Pharoah PD,Tsai YY,Ramus SJ,Phelan CM,Goode EL,Lawrenson K,Buckley M,Fridley BL,Tyrer JP,Shen H,Weber R,Karevan R,Larson MC,Song H,Tessier DC,Bacot F,Vincent D,Cunningham JM,Dennis J,Dicks E,,,Aben KK,Anton-Culver H,Antonenkova N,Armasu SM,Baglietto L,Bandera EV,Beckmann MW,Birrer MJ,Bloom G,Bogdanova N,Brenton JD,Brinton LA,Brooks-Wilson A,Brown R,Butzow R,Campbell I,Carney ME,Carvalho RS,Chang-Claude J,Chen YA,Chen Z,Chow WH,Cicek MS,Coetzee G,Cook LS,Cramer DW,Cybulski C,Dansonka-Mieszkowska A,Despierre E,Doherty JA,D?rk T,du Bois A,D?rst M,Eccles D,Edwards R,Ekici AB,Fasching PA,Fenstermacher D,Flanagan J,Gao YT,Garcia-Closas M,Gentry-Maharaj A,Giles G,Gjyshi A,Gore M,Gronwald J,Guo Q,Halle MK,Harter P,Hein A,Heitz F,Hillemanns P,Hoatlin M,H?gdall E,H?gdall CK,Hosono S,Jakubowska A,Jensen A,Kalli KR,Karlan BY,Kelemen LE,Kiemeney LA,Kjaer SK,Konecny GE,Krakstad C,Kupryjanczyk J,Lambrechts D,Lambrechts S,Le ND,Lee N,Lee J,Leminen A,Lim BK,Lissowska J,Lubi?ski J,Lundvall L,Lurie G,Massuger LF,Matsuo K,McGuire V,McLaughlin JR,Menon U,Modugno F,Moysich KB,Nakanishi T,Narod SA,Ness RB,Nevanlinna H,Nickels S,Noushmehr H,Odunsi K,Olson S,Orlow I,Paul J,Pejovic T,Pelttari LM,Permuth-Wey J,Pike MC,Poole EM,Qu X,Risch HA,Rodriguez-Rodriguez L,Rossing MA,Rudolph A,Runnebaum I,Rzepecka IK,Salvesen HB,Schwaab I,Severi G,Shen H,Shridhar V,Shu XO,Sieh W,Southey MC,Spellman P,Tajima K,Teo SH,Terry KL,Thompson PJ,Timorek A,Tworoger SS,van Altena AM,van den Berg D,Vergote I,Vierkant RA,Vitonis AF,Wang-Gohrke S,Wentzensen N,Whittemore AS,Wik E,Winterhoff B,Woo YL,Wu AH,Yang HP,Zheng W,Ziogas A,Zulkifli F,Goodman MT,Hall P,Easton DF,Pearce CL,Berchuck A,Chenevix-Trench G,Iversen E,Monteiro AN,Gayther SA,Schildkraut JM,Sellers TA

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SOCS7 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム